Canonical Allele Identifier: CA505371450

Gene: TYK2

Linked Data

• gnomAD v4: 19-10352536-G-A
• MyVariant Identifiers: chr19:g.10463212G>A (hg19)

Genomic Alleles

HGVS	Genome Assembly
NC_000019.10:g.10352536G>A , CM000681.2:g.10352536G>A	GRCh38
NC_000019.9:g.10463212G>A , CM000681.1:g.10463212G>A	GRCh37
NC_000019.8:g.10324212G>A	NCBI36
NG_007872.1:g.33037C>T , LRG_121:g.33037C>T

Transcript Alleles

HGVS	Amino-acid Change
ENST00000524470.2:c.*1565C>T	ENSP00000514307.1:n.*1565C>T
ENST00000525976.6:c.3216C>T	ENSP00000434831.2:p.Cys1072=
ENST00000527481.3:c.3097C>T	ENSP00000466340.2:p.Pro1033Ser
ENST00000529370.6:n.4592C>T
ENST00000529739.2:n.4025C>T
ENST00000530829.2:c.*2767C>T	ENSP00000436826.2:n.*2767C>T
ENST00000531836.6:c.3216C>T	ENSP00000436175.2:p.Cys1072=
ENST00000533334.2:c.*1242+390C>T	ENSP00000432320.2:n.*1242+390C>T
ENST00000534228.2:n.5054+390C>T
ENST00000699354.1:n.1318C>T
ENST00000699355.1:c.*2716C>T	ENSP00000514328.1:n.*2716C>T
ENST00000699356.1:n.4025C>T
ENST00000699357.1:n.5070C>T
ENST00000699358.1:c.3200+390C>T	ENSP00000514329.1:n.3200+390C>T
ENST00000699359.1:c.390C>T
ENST00000699360.1:c.3174C>T	ENSP00000514331.1:p.Cys1058=
ENST00000699361.1:n.250C>T
ENST00000699362.1:c.112C>T	ENSP00000514332.1:p.Pro38Ser
ENST00000699363.1:c.112C>T	ENSP00000514333.1:p.Pro38Ser
ENST00000699364.1:n.216C>T
ENST00000699365.1:c.285C>T	ENSP00000514334.1:p.Cys95=
ENST00000699366.1:n.111+1278C>T
ENST00000699367.1:n.111+1278C>T
ENST00000699368.1:c.703C>T	ENSP00000514335.1:n.703C>T
ENST00000525621.6:c.3216C>T MANE Select	ENSP00000431885.1:p.Cys1072=
ENST00000264818.10:c.3216C>T	ENSP00000264818.6:p.Cys1072=
ENST00000524462.5:c.2661C>T	ENSP00000433203.1:p.Cys887=
ENST00000525621.5:c.3216C>T	ENSP00000431885.1:p.Cys1072=
ENST00000527481.2:c.393C>T
ENST00000529422.1:n.116+486C>T
ENST00000529739.1:c.285C>T	ENSP00000436155.1:p.Cys95=
ENST00000530220.1:n.331+390C>T
ENST00000530560.5:c.337+1506C>T	ENSP00000465291.1:n.337+1506C>T
ENST00000592137.1:n.370C>T
NM_003331.4:c.3216C>T , LRG_121t1:c.3216C>T	NP_003322.3:p.Cys1072=
XM_011528245.1:c.3216C>T	XP_011526547.1:p.Cys1072=
XM_011528246.1:c.2919C>T	XP_011526548.1:p.Cys973=
XM_011528247.1:c.2919C>T	XP_011526549.1:p.Cys973=
XM_011528248.1:c.3200+390C>T	XP_011526550.1:n.3200+390C>T
XM_011528249.1:c.1890C>T	XP_011526551.1:p.Cys630=
XM_011528251.1:c.1473C>T	XP_011526553.1:p.Cys491=
XM_011528246.3:c.2919C>T	XP_011526548.1:p.Cys973=
XM_011528249.2:c.1890C>T	XP_011526551.1:p.Cys630=
XR_001753750.1:n.3357+390C>T
XR_001753751.1:n.3768C>T
XR_002958353.1:n.4694C>T
NM_003331.5:c.3216C>T MANE Select	NP_003322.3:p.Cys1072=
NM_001385197.1:c.3216C>T	NP_001372126.1:p.Cys1072=
NM_001385198.1:c.3168+422C>T	NP_001372127.1:n.3168+422C>T
NM_001385199.1:c.3030C>T	NP_001372128.1:p.Cys1010=
NM_001385200.1:c.3213C>T	NP_001372129.1:p.Cys1071=
NM_001385201.1:c.3018C>T	NP_001372130.1:p.Cys1006=
NM_001385202.1:c.3132C>T	NP_001372131.1:p.Cys1044=
NM_001385203.1:c.3297C>T	NP_001372132.1:p.Cys1099=
NM_001385204.1:c.3426C>T	NP_001372133.1:p.Cys1142=
NM_001385205.1:c.3126C>T	NP_001372134.1:p.Cys1042=
NM_001385206.1:c.3090C>T	NP_001372135.1:p.Cys1030=
NM_001385207.1:c.3198C>T	NP_001372136.1:p.Cys1066=