Canonical Allele Identifier: CA4718131
Gene: FGFR1 HGNC NCBI

Linked Data

ClinVar Variation Id: 391205
dbSNP Id: rs201490643
gnomAD v2: 8-38271450-A-G
gnomAD v3: 8-38413932-A-G
gnomAD v4: 8-38413932-A-G

Genomic Alleles

HGVS Genome Assembly
NC_000008.11:g.38413932A>G , CM000670.2:g.38413932A>G GRCh38
NC_000008.10:g.38271450A>G , CM000670.1:g.38271450A>G GRCh37
NC_000008.9:g.38390607A>G NCBI36
NG_007729.1:g.59903T>C

Transcript Alleles

HGVS Amino-acid Change
ENST00000703405.1:c.2278T>C ENSP00000515291.1:p.Leu760=
ENST00000341462.9:c.2266T>C ENSP00000340636.7:p.Leu756=
ENST00000425967.8:c.2266T>C ENSP00000393312.4:p.Leu756=
ENST00000524528.2:n.3171T>C
ENST00000682398.1:n.1518T>C
ENST00000683132.1:n.968T>C
ENST00000683765.1:c.2458T>C ENSP00000507039.1:p.Leu820=
ENST00000683815.1:c.2266T>C ENSP00000507997.1:p.Leu756=
ENST00000683948.1:n.2966T>C
ENST00000684654.1:c.1999T>C ENSP00000507205.1:p.Leu667=
ENST00000447712.7:c.2278T>C MANE Select ENSP00000400162.2:p.Leu760=
ENST00000649678.1:c.2266T>C ENSP00000497266.1:p.Leu756=
ENST00000674189.1:c.*1924T>C ENSP00000501345.1:n.*1924T>C
ENST00000674380.1:c.*2245T>C ENSP00000501514.1:n.*2245T>C
ENST00000674474.1:n.3772T>C
ENST00000326324.10:c.2005T>C ENSP00000327229.6:p.Leu669=
ENST00000335922.9:c.2248T>C ENSP00000337247.5:p.Leu750=
ENST00000341462.8:c.*1328T>C ENSP00000340636.6:n.*1328T>C
ENST00000356207.9:c.2011T>C ENSP00000348537.5:p.Leu671=
ENST00000397091.9:c.2272T>C ENSP00000380280.5:p.Leu758=
ENST00000397103.5:c.2011T>C ENSP00000380292.1:p.Leu671=
ENST00000397108.8:c.2272T>C ENSP00000380297.4:p.Leu758=
ENST00000397113.6:c.2272T>C ENSP00000380302.2:p.Leu758=
ENST00000425967.7:c.2371T>C ENSP00000393312.3:p.Leu791=
ENST00000447712.6:c.2278T>C ENSP00000400162.2:p.Leu760=
ENST00000526570.5:n.4557T>C
ENST00000526688.1:n.45T>C
ENST00000531196.5:c.489T>C ENSP00000434800.1:n.489T>C
ENST00000532791.5:c.2272T>C ENSP00000432972.1:p.Leu758=
ENST00000619564.3:c.*1173T>C ENSP00000484553.1:n.*1173T>C
NM_001174063.1:c.2272T>C NP_001167534.1:p.Leu758=
NM_001174064.1:c.2248T>C NP_001167535.1:p.Leu750=
NM_001174065.1:c.2272T>C NP_001167536.1:p.Leu758=
NM_001174066.1:c.2011T>C NP_001167537.1:p.Leu671=
NM_001174067.1:c.2371T>C NP_001167538.1:p.Leu791=
NM_015850.3:c.2272T>C NP_056934.2:p.Leu758=
NM_023105.2:c.2011T>C NP_075593.1:p.Leu671=
NM_023106.2:c.2005T>C NP_075594.1:p.Leu669=
NM_023110.2:c.2278T>C NP_075598.2:p.Leu760=
XM_006716303.2:c.2278T>C XP_006716366.1:p.Leu760=
XM_006716304.1:c.2278T>C XP_006716367.1:p.Leu760=
XM_006716305.2:c.2278T>C XP_006716368.1:p.Leu760=
XM_006716306.2:c.2272T>C XP_006716369.1:p.Leu758=
XM_006716307.1:c.2272T>C XP_006716370.1:p.Leu758=
XM_006716309.2:c.2254T>C XP_006716372.1:p.Leu752=
XM_006716310.2:c.2011T>C XP_006716373.1:p.Leu671=
XM_006716311.1:c.2011T>C XP_006716374.1:p.Leu671=
XM_006716312.1:c.2011T>C XP_006716375.1:p.Leu671=
XM_006716313.2:c.2005T>C XP_006716376.1:p.Leu669=
XM_006716314.1:c.2005T>C XP_006716377.1:p.Leu669=
XM_011544443.1:c.2377T>C XP_011542745.1:p.Leu793=
XM_011544444.1:c.2371T>C XP_011542746.1:p.Leu791=
XM_011544445.1:c.2371T>C XP_011542747.1:p.Leu791=
XM_011544446.1:c.2377T>C XP_011542748.1:p.Leu793=
XM_011544447.1:c.2371T>C XP_011542749.1:p.Leu791=
XM_011544448.1:c.2110T>C XP_011542750.1:p.Leu704=
XM_011544449.1:c.2104T>C XP_011542751.1:p.Leu702=
XM_011544450.1:c.2104T>C XP_011542752.1:p.Leu702=
XM_011544451.1:c.1987T>C XP_011542753.1:p.Leu663=
NM_001354367.1:c.2272T>C NP_001341296.1:p.Leu758=
NM_001354368.1:c.1999T>C NP_001341297.1:p.Leu667=
NM_001354369.1:c.2266T>C NP_001341298.1:p.Leu756=
NM_001354370.1:c.2005T>C NP_001341299.1:p.Leu669=
XM_006716303.3:c.2278T>C XP_006716366.1:p.Leu760=
XM_006716310.3:c.2011T>C XP_006716373.1:p.Leu671=
XM_006716312.2:c.2011T>C XP_006716375.1:p.Leu671=
XM_006716314.2:c.2005T>C XP_006716377.1:p.Leu669=
XM_011544443.2:c.2377T>C XP_011542745.1:p.Leu793=
XM_011544445.2:c.2371T>C XP_011542747.1:p.Leu791=
XM_011544446.2:c.2377T>C XP_011542748.1:p.Leu793=
XM_011544447.2:c.2371T>C XP_011542749.1:p.Leu791=
XM_011544450.2:c.2104T>C XP_011542752.1:p.Leu702=
XM_017013219.1:c.2365T>C XP_016868708.1:p.Leu789=
XM_017013220.1:c.2365T>C XP_016868709.1:p.Leu789=
XM_017013221.1:c.2278T>C XP_016868710.1:p.Leu760=
XM_017013222.2:c.2272T>C XP_016868711.1:p.Leu758=
XM_017013224.2:c.2266T>C XP_016868713.1:p.Leu756=
XM_017013225.2:c.2266T>C XP_016868714.1:p.Leu756=
XM_017013226.1:c.2104T>C XP_016868715.1:p.Leu702=
XM_017013227.1:c.2098T>C XP_016868716.1:p.Leu700=
XM_017013229.2:c.1306T>C XP_016868718.1:p.Leu436=
XM_017013230.1:c.1306T>C XP_016868719.1:p.Leu436=
XM_024447097.1:c.2254T>C XP_024302865.1:p.Leu752=
XR_001745495.1:n.2551T>C
XR_001745496.1:n.2551T>C
NM_001174063.2:c.2272T>C NP_001167534.1:p.Leu758=
NM_001174064.2:c.2248T>C NP_001167535.1:p.Leu750=
NM_001174065.2:c.2272T>C NP_001167536.1:p.Leu758=
NM_001174066.2:c.2011T>C NP_001167537.1:p.Leu671=
NM_001354368.2:c.1999T>C NP_001341297.1:p.Leu667=
NM_015850.4:c.2272T>C NP_056934.2:p.Leu758=
NM_023105.3:c.2011T>C NP_075593.1:p.Leu671=
NM_023106.3:c.2005T>C NP_075594.1:p.Leu669=
NM_023110.3:c.2278T>C MANE Select NP_075598.2:p.Leu760=
NM_001174067.2:c.2371T>C NP_001167538.1:p.Leu791=
NM_001354367.2:c.2272T>C NP_001341296.1:p.Leu758=
NM_001354369.2:c.2266T>C NP_001341298.1:p.Leu756=
NM_001354370.2:c.2005T>C NP_001341299.1:p.Leu669=