Canonical Allele Identifier: CA403995102

Gene: TYK2

Linked Data

• gnomAD v4: 19-10357774-C-G
• MyVariant Identifiers: chr19:g.10468450C>G (hg19) ; chr19:g.10357774C>G (hg38)

Genomic Alleles

HGVS	Genome Assembly
NC_000019.10:g.10357774C>G , CM000681.2:g.10357774C>G	GRCh38
NC_000019.9:g.10468450C>G , CM000681.1:g.10468450C>G	GRCh37
NC_000019.8:g.10329450C>G	NCBI36
NG_007872.1:g.27799G>C , LRG_121:g.27799G>C

Transcript Alleles

HGVS	Amino-acid Change
ENST00000524470.2:c.*805G>C	ENSP00000514307.1:n.*805G>C
ENST00000525976.6:c.2456G>C	ENSP00000434831.2:p.Ser819Thr
ENST00000527481.3:c.2456G>C	ENSP00000466340.2:p.Ser819Thr
ENST00000529370.6:n.2787G>C
ENST00000529739.2:n.2870G>C
ENST00000530829.2:c.*2007G>C	ENSP00000436826.2:n.*2007G>C
ENST00000531836.6:c.2456G>C	ENSP00000436175.2:p.Ser819Thr
ENST00000533334.2:c.*498G>C	ENSP00000432320.2:n.*498G>C
ENST00000534228.2:n.2870G>C
ENST00000699354.1:n.558G>C
ENST00000699355.1:c.*516G>C	ENSP00000514328.1:n.*516G>C
ENST00000699356.1:n.2870G>C
ENST00000699357.1:n.2870G>C
ENST00000699358.1:c.2456G>C	ENSP00000514329.1:p.Ser819Thr
ENST00000699360.1:c.2456G>C	ENSP00000514331.1:p.Ser819Thr
ENST00000525621.6:c.2456G>C MANE Select	ENSP00000431885.1:p.Ser819Thr
ENST00000264818.10:c.2456G>C	ENSP00000264818.6:p.Ser819Thr
ENST00000524462.5:c.1901G>C	ENSP00000433203.1:p.Ser634Thr
ENST00000525621.5:c.2456G>C	ENSP00000431885.1:p.Ser819Thr
ENST00000529370.5:c.2456G>C	ENSP00000432728.1:p.Ser819Thr
ENST00000529412.1:n.128G>C
NM_003331.4:c.2456G>C , LRG_121t1:c.2456G>C	NP_003322.3:p.Ser819Thr
XM_011528245.1:c.2456G>C	XP_011526547.1:p.Ser819Thr
XM_011528246.1:c.2159G>C	XP_011526548.1:p.Ser720Thr
XM_011528247.1:c.2159G>C	XP_011526549.1:p.Ser720Thr
XM_011528248.1:c.2456G>C	XP_011526550.1:p.Ser819Thr
XM_011528249.1:c.1130G>C	XP_011526551.1:p.Ser377Thr
XM_011528251.1:c.713G>C	XP_011526553.1:p.Ser238Thr
XM_011528246.3:c.2159G>C	XP_011526548.1:p.Ser720Thr
XM_011528249.2:c.1130G>C	XP_011526551.1:p.Ser377Thr
XR_001753750.1:n.2613G>C
XR_001753751.1:n.2613G>C
XR_002958353.1:n.2494G>C
NM_003331.5:c.2456G>C MANE Select	NP_003322.3:p.Ser819Thr
NM_001385197.1:c.2456G>C	NP_001372126.1:p.Ser819Thr
NM_001385198.1:c.2456G>C	NP_001372127.1:p.Ser819Thr
NM_001385199.1:c.2270G>C	NP_001372128.1:p.Ser757Thr
NM_001385200.1:c.2456G>C	NP_001372129.1:p.Ser819Thr
NM_001385201.1:c.2258G>C	NP_001372130.1:p.Ser753Thr
NM_001385202.1:c.2372G>C	NP_001372131.1:p.Ser791Thr
NM_001385203.1:c.2456G>C	NP_001372132.1:p.Ser819Thr
NM_001385204.1:c.2456G>C	NP_001372133.1:p.Ser819Thr
NM_001385205.1:c.2366G>C	NP_001372134.1:p.Ser789Thr
NM_001385206.1:c.2330G>C	NP_001372135.1:p.Ser777Thr
NM_001385207.1:c.2438G>C	NP_001372136.1:p.Ser813Thr