Canonical Allele Identifier: CA403987782

Gene: TYK2

Linked Data

• gnomAD v4: 19-10354073-G-C
• MyVariant Identifiers: chr19:g.10464749G>C (hg19) ; chr19:g.10354073G>C (hg38)

Genomic Alleles

HGVS	Genome Assembly
NC_000019.10:g.10354073G>C , CM000681.2:g.10354073G>C	GRCh38
NC_000019.9:g.10464749G>C , CM000681.1:g.10464749G>C	GRCh37
NC_000019.8:g.10325749G>C	NCBI36
NG_007872.1:g.31500C>G , LRG_121:g.31500C>G

Transcript Alleles

HGVS	Amino-acid Change
ENST00000524470.2:c.*1226C>G	ENSP00000514307.1:n.*1226C>G
ENST00000525976.6:c.2877C>G	ENSP00000434831.2:p.Ile959Met
ENST00000527481.3:c.2877C>G	ENSP00000466340.2:p.Ile959Met
ENST00000529370.6:n.4253C>G
ENST00000529739.2:n.3291C>G
ENST00000530829.2:c.*2428C>G	ENSP00000436826.2:n.*2428C>G
ENST00000531836.6:c.2877C>G	ENSP00000436175.2:p.Ile959Met
ENST00000533334.2:c.*919C>G	ENSP00000432320.2:n.*919C>G
ENST00000534228.2:n.4336C>G
ENST00000699354.1:n.979C>G
ENST00000699355.1:c.*1982C>G	ENSP00000514328.1:n.*1982C>G
ENST00000699356.1:n.3291C>G
ENST00000699357.1:n.4336C>G
ENST00000699358.1:c.2877C>G	ENSP00000514329.1:p.Ile959Met
ENST00000699359.1:c.83C>G
ENST00000699360.1:c.2877C>G	ENSP00000514331.1:p.Ile959Met
ENST00000699368.1:c.81C>G	ENSP00000514335.1:p.Ile27Met
ENST00000525621.6:c.2877C>G MANE Select	ENSP00000431885.1:p.Ile959Met
ENST00000264818.10:c.2877C>G	ENSP00000264818.6:p.Ile959Met
ENST00000524462.5:c.2322C>G	ENSP00000433203.1:p.Ile774Met
ENST00000525621.5:c.2877C>G	ENSP00000431885.1:p.Ile959Met
ENST00000527481.2:c.173C>G
ENST00000529412.1:n.549C>G
ENST00000529739.1:c.-450C>G	ENSP00000436155.1:n.-450C>G
ENST00000530560.5:c.306C>G	ENSP00000465291.1:p.Ile102Met
ENST00000592137.1:n.31C>G
NM_003331.4:c.2877C>G , LRG_121t1:c.2877C>G	NP_003322.3:p.Ile959Met
XM_011528245.1:c.2877C>G	XP_011526547.1:p.Ile959Met
XM_011528246.1:c.2580C>G	XP_011526548.1:p.Ile860Met
XM_011528247.1:c.2580C>G	XP_011526549.1:p.Ile860Met
XM_011528248.1:c.2877C>G	XP_011526550.1:p.Ile959Met
XM_011528249.1:c.1551C>G	XP_011526551.1:p.Ile517Met
XM_011528251.1:c.1134C>G	XP_011526553.1:p.Ile378Met
XM_011528246.3:c.2580C>G	XP_011526548.1:p.Ile860Met
XM_011528249.2:c.1551C>G	XP_011526551.1:p.Ile517Met
XR_001753750.1:n.3034C>G
XR_001753751.1:n.3034C>G
XR_002958353.1:n.3960C>G
NM_003331.5:c.2877C>G MANE Select	NP_003322.3:p.Ile959Met
NM_001385197.1:c.2877C>G	NP_001372126.1:p.Ile959Met
NM_001385198.1:c.2877C>G	NP_001372127.1:p.Ile959Met
NM_001385199.1:c.2691C>G	NP_001372128.1:p.Ile897Met
NM_001385200.1:c.2874C>G	NP_001372129.1:p.Ile958Met
NM_001385201.1:c.2679C>G	NP_001372130.1:p.Ile893Met
NM_001385202.1:c.2793C>G	NP_001372131.1:p.Ile931Met
NM_001385203.1:c.2958C>G	NP_001372132.1:p.Ile986Met
NM_001385204.1:c.3087C>G	NP_001372133.1:p.Ile1029Met
NM_001385205.1:c.2787C>G	NP_001372134.1:p.Ile929Met
NM_001385206.1:c.2751C>G	NP_001372135.1:p.Ile917Met
NM_001385207.1:c.2859C>G	NP_001372136.1:p.Ile953Met