Canonical Allele Identifier: CA403987646

Gene: TYK2

Linked Data

• COSMIC: COSM1680639
• MyVariant Identifiers: chr19:g.10464731G>T (hg19) ; chr19:g.10354055G>T (hg38)

Genomic Alleles

HGVS	Genome Assembly
NC_000019.10:g.10354055G>T , CM000681.2:g.10354055G>T	GRCh38
NC_000019.9:g.10464731G>T , CM000681.1:g.10464731G>T	GRCh37
NC_000019.8:g.10325731G>T	NCBI36
NG_007872.1:g.31518C>A , LRG_121:g.31518C>A

Transcript Alleles

HGVS	Amino-acid Change
ENST00000524470.2:c.*1244C>A	ENSP00000514307.1:n.*1244C>A
ENST00000525976.6:c.2895C>A	ENSP00000434831.2:p.Cys965Ter
ENST00000527481.3:c.2895C>A	ENSP00000466340.2:p.Cys965Ter
ENST00000529370.6:n.4271C>A
ENST00000529739.2:n.3309C>A
ENST00000530829.2:c.*2446C>A	ENSP00000436826.2:n.*2446C>A
ENST00000531836.6:c.2895C>A	ENSP00000436175.2:p.Cys965Ter
ENST00000533334.2:c.*937C>A	ENSP00000432320.2:n.*937C>A
ENST00000534228.2:n.4354C>A
ENST00000699354.1:n.997C>A
ENST00000699355.1:c.*2000C>A	ENSP00000514328.1:n.*2000C>A
ENST00000699356.1:n.3309C>A
ENST00000699357.1:n.4354C>A
ENST00000699358.1:c.2895C>A	ENSP00000514329.1:p.Cys965Ter
ENST00000699359.1:c.101C>A
ENST00000699360.1:c.2895C>A	ENSP00000514331.1:p.Cys965Ter
ENST00000699368.1:c.99C>A	ENSP00000514335.1:p.Cys33Ter
ENST00000525621.6:c.2895C>A MANE Select	ENSP00000431885.1:p.Cys965Ter
ENST00000264818.10:c.2895C>A	ENSP00000264818.6:p.Cys965Ter
ENST00000524462.5:c.2340C>A	ENSP00000433203.1:p.Cys780Ter
ENST00000525621.5:c.2895C>A	ENSP00000431885.1:p.Cys965Ter
ENST00000527481.2:c.191C>A
ENST00000529412.1:n.567C>A
ENST00000529739.1:c.-432C>A	ENSP00000436155.1:n.-432C>A
ENST00000530560.5:c.324C>A	ENSP00000465291.1:p.Cys108Ter
ENST00000592137.1:n.49C>A
NM_003331.4:c.2895C>A , LRG_121t1:c.2895C>A	NP_003322.3:p.Cys965Ter
XM_011528245.1:c.2895C>A	XP_011526547.1:p.Cys965Ter
XM_011528246.1:c.2598C>A	XP_011526548.1:p.Cys866Ter
XM_011528247.1:c.2598C>A	XP_011526549.1:p.Cys866Ter
XM_011528248.1:c.2895C>A	XP_011526550.1:p.Cys965Ter
XM_011528249.1:c.1569C>A	XP_011526551.1:p.Cys523Ter
XM_011528251.1:c.1152C>A	XP_011526553.1:p.Cys384Ter
XM_011528246.3:c.2598C>A	XP_011526548.1:p.Cys866Ter
XM_011528249.2:c.1569C>A	XP_011526551.1:p.Cys523Ter
XR_001753750.1:n.3052C>A
XR_001753751.1:n.3052C>A
XR_002958353.1:n.3978C>A
NM_003331.5:c.2895C>A MANE Select	NP_003322.3:p.Cys965Ter
NM_001385197.1:c.2895C>A	NP_001372126.1:p.Cys965Ter
NM_001385198.1:c.2895C>A	NP_001372127.1:p.Cys965Ter
NM_001385199.1:c.2709C>A	NP_001372128.1:p.Cys903Ter
NM_001385200.1:c.2892C>A	NP_001372129.1:p.Cys964Ter
NM_001385201.1:c.2697C>A	NP_001372130.1:p.Cys899Ter
NM_001385202.1:c.2811C>A	NP_001372131.1:p.Cys937Ter
NM_001385203.1:c.2976C>A	NP_001372132.1:p.Cys992Ter
NM_001385204.1:c.3105C>A	NP_001372133.1:p.Cys1035Ter
NM_001385205.1:c.2805C>A	NP_001372134.1:p.Cys935Ter
NM_001385206.1:c.2769C>A	NP_001372135.1:p.Cys923Ter
NM_001385207.1:c.2877C>A	NP_001372136.1:p.Cys959Ter