Canonical Allele Identifier: CA369541122

Gene: BRAF

Linked Data

• gnomAD v4: 7-140749379-T-C
• MyVariant Identifiers: chr7:g.140449179T>C (hg19) ; chr7:g.140749379T>C (hg38)

Genomic Alleles

HGVS	Genome Assembly
NC_000007.14:g.140749379T>C , CM000669.2:g.140749379T>C	GRCh38
NC_000007.13:g.140449179T>C , CM000669.1:g.140449179T>C	GRCh37
NC_000007.12:g.140095648T>C	NCBI36
NG_007873.3:g.180386A>G , LRG_299:g.180386A>G

Transcript Alleles

HGVS	Amino-acid Change
ENST00000646891.2:c.1900A>G MANE Select	ENSP00000493543.1:p.Ser634Gly
ENST00000288602.11:c.2020A>G	ENSP00000288602.7:p.Ser674Gly
ENST00000479537.6:c.570A>G
ENST00000496384.7:c.1900A>G	ENSP00000419060.2:p.Ser634Gly
ENST00000497784.2:c.*1350A>G	ENSP00000420119.2:n.*1350A>G
ENST00000642228.1:c.*978A>G	ENSP00000493678.1:n.*978A>G
ENST00000642875.1:n.1298A>G
ENST00000644120.1:n.2290A>G
ENST00000644650.1:c.996A>G
ENST00000644905.1:n.2782A>G
ENST00000644969.2:c.2020A>G MANE Plus Clinical	ENSP00000496776.1:p.Ser674Gly
ENST00000646730.1:c.*476A>G	ENSP00000494784.1:n.*476A>G
ENST00000646891.1:c.1900A>G	ENSP00000493543.1:p.Ser634Gly
ENST00000647434.1:c.777A>G	ENSP00000495132.1:p.Thr259=
ENST00000288602.10:c.1900A>G	ENSP00000288602.6:p.Ser634Gly
ENST00000479537.5:c.184A>G	ENSP00000418033.1:p.Ser62Gly
ENST00000496384.6:c.723A>G
ENST00000497784.1:c.1935A>G	ENSP00000420119.1:n.1935A>G
NM_004333.4:c.1900A>G , LRG_299t1:c.1900A>G	NP_004324.2:p.Ser634Gly
XM_005250045.1:c.1900A>G	XP_005250102.1:p.Ser634Gly
XM_005250046.1:c.1900A>G	XP_005250103.1:p.Ser634Gly
XM_011516529.1:c.1900A>G	XP_011514831.1:p.Ser634Gly
XM_011516530.1:c.1734A>G	XP_011514832.1:p.Thr578=
XR_242190.1:n.1908A>G
XR_927520.1:n.1908A>G
XR_927521.1:n.1908A>G
XR_927522.1:n.1742A>G
XR_927523.1:n.1742A>G
NM_001354609.1:c.1900A>G	NP_001341538.1:p.Ser634Gly
NM_004333.5:c.1900A>G	NP_004324.2:p.Ser634Gly
NR_148928.1:n.2998A>G
XM_017012558.1:c.2020A>G	XP_016868047.1:p.Ser674Gly
XM_017012559.1:c.2020A>G	XP_016868048.1:p.Ser674Gly
XR_001744857.1:n.2028A>G
XR_001744858.1:n.1862A>G
NM_001354609.2:c.1900A>G	NP_001341538.1:p.Ser634Gly
NM_001374244.1:c.2020A>G	NP_001361173.1:p.Ser674Gly
NM_001374258.1:c.2020A>G MANE Plus Clinical	NP_001361187.1:p.Ser674Gly
NM_004333.6:c.1900A>G MANE Select	NP_004324.2:p.Ser634Gly
NM_001378467.1:c.1909A>G	NP_001365396.1:p.Ser637Gly
NM_001378468.1:c.1900A>G	NP_001365397.1:p.Ser634Gly
NM_001378469.1:c.1834A>G	NP_001365398.1:p.Ser612Gly
NM_001378470.1:c.1798A>G	NP_001365399.1:p.Ser600Gly
NM_001378471.1:c.1789A>G	NP_001365400.1:p.Ser597Gly
NM_001378472.1:c.1744A>G	NP_001365401.1:p.Ser582Gly
NM_001378473.1:c.1744A>G	NP_001365402.1:p.Ser582Gly
NM_001378474.1:c.1900A>G	NP_001365403.1:p.Ser634Gly
NM_001378475.1:c.1636A>G	NP_001365404.1:p.Ser546Gly