Canonical Allele Identifier: CA280058
Gene: BRAF HGNC NCBI

Linked Data

ClinVar Variation Id: 177672
dbSNP Id: rs121913341
COSMIC: COSM468
CIViC: CA280058

Genomic Alleles

HGVS Genome Assembly
NC_000007.14:g.140753350A>C , CM000669.2:g.140753350A>C GRCh38
NC_000007.13:g.140453150A>C , CM000669.1:g.140453150A>C GRCh37
NC_000007.12:g.140099619A>C NCBI36
NG_007873.3:g.176415T>G , LRG_299:g.176415T>G

Transcript Alleles

HGVS Amino-acid change
ENST00000288602.11:c.1905T>G ENSP00000288602.7:p.Phe635Leu
ENST00000479537.6:n.455T>G
ENST00000496384.7:c.1785T>G ENSP00000419060.2:p.Phe595Leu
ENST00000497784.2:c.*1235T>G ENSP00000420119.2:p.=
ENST00000642228.1:c.*863T>G ENSP00000493678.1:p.=
ENST00000642875.1:n.1259-3932T>G
ENST00000644120.1:n.2175T>G
ENST00000644650.1:n.881T>G
ENST00000644905.1:n.2667T>G
ENST00000644969.2:c.1905T>G MANE Plus Clinical ENSP00000496776.1:p.Phe635Leu
ENST00000646730.1:c.*361T>G ENSP00000494784.1:p.=
ENST00000646891.1:c.1785T>G ENSP00000493543.1:p.Phe595Leu
ENST00000647434.1:n.738-3932T>G ENSP00000495132.1:p.=
ENST00000288602.10:c.1785T>G ENSP00000288602.6:p.Phe595Leu
ENST00000479537.5:n.69T>G ENSP00000418033.1:p.Phe23Leu
ENST00000496384.6:n.608T>G
ENST00000497784.1:n.1820T>G ENSP00000420119.1:p.=
NM_004333.4:c.1785T>G , LRG_299t1:c.1785T>G NP_004324.2:p.Phe595Leu
XM_005250045.1:c.1785T>G XP_005250102.1:p.Phe595Leu
XM_005250046.1:c.1785T>G XP_005250103.1:p.Phe595Leu
XM_011516529.1:c.1785T>G XP_011514831.1:p.Phe595Leu
XM_011516530.1:c.1695-3932T>G XP_011514832.1:p.=
XR_242190.1:n.1793T>G
XR_927520.1:n.1793T>G
XR_927521.1:n.1793T>G
XR_927522.1:n.1703-3932T>G
XR_927523.1:n.1703-3932T>G
NM_001354609.1:c.1785T>G NP_001341538.1:p.Phe595Leu
NM_004333.5:c.1785T>G NP_004324.2:p.Phe595Leu
NR_148928.1:n.2883T>G
XM_017012558.1:c.1905T>G XP_016868047.1:p.Phe635Leu
XM_017012559.1:c.1905T>G XP_016868048.1:p.Phe635Leu
XR_001744857.1:n.1913T>G
XR_001744858.1:n.1823-3932T>G
NM_001354609.2:c.1785T>G NP_001341538.1:p.Phe595Leu
NM_001374244.1:c.1905T>G NP_001361173.1:p.Phe635Leu
NM_001374258.1:c.1905T>G MANE Plus Clinical NP_001361187.1:p.Phe635Leu
NM_004333.6:c.1785T>G MANE Select NP_004324.2:p.Phe595Leu
NM_001378467.1:c.1794T>G NP_001365396.1:p.Phe598Leu
NM_001378468.1:c.1785T>G NP_001365397.1:p.Phe595Leu
NM_001378469.1:c.1719T>G NP_001365398.1:p.Phe573Leu
NM_001378470.1:c.1683T>G NP_001365399.1:p.Phe561Leu
NM_001378471.1:c.1674T>G NP_001365400.1:p.Phe558Leu
NM_001378472.1:c.1629T>G NP_001365401.1:p.Phe543Leu
NM_001378473.1:c.1629T>G NP_001365402.1:p.Phe543Leu
NM_001378474.1:c.1785T>G NP_001365403.1:p.Phe595Leu
NM_001378475.1:c.1521T>G NP_001365404.1:p.Phe507Leu