Chr Mutation (hg38) CAid Gene Transcript Linkouts
7g.99760869G>ACA456686468CYP3A4c.1459C>T (p.Leu487=)
n.801C>T
c.1366C>T (p.Leu456=)
c.907C>T (p.Leu303=)
c.1219C>T (p.Leu407=)
c.916C>T (p.Leu306=)
c.1363C>T (p.Leu455=)
c.1456C>T (p.Leu486=)
 gnomAD v4
7g.99760869G>CCA368367710CYP3A4c.1459C>G (p.Leu487Val)
n.801C>G
c.1366C>G (p.Leu456Val)
c.907C>G (p.Leu303Val)
c.1219C>G (p.Leu407Val)
c.916C>G (p.Leu306Val)
c.1363C>G (p.Leu455Val)
c.1456C>G (p.Leu486Val)
 gnomAD v4
7g.99760869G>TCA368367712CYP3A4c.1459C>A (p.Leu487Ile)
n.801C>A
c.1366C>A (p.Leu456Ile)
c.907C>A (p.Leu303Ile)
c.1219C>A (p.Leu407Ile)
c.916C>A (p.Leu306Ile)
c.1363C>A (p.Leu455Ile)
c.1456C>A (p.Leu486Ile)
7g.99760870A>CCA456686472CYP3A4c.1458T>G (p.Ala486=)
n.800T>G
c.1365T>G (p.Ala455=)
c.906T>G (p.Ala302=)
c.1218T>G (p.Ala406=)
c.915T>G (p.Ala305=)
c.1362T>G (p.Ala454=)
c.1455T>G (p.Ala485=)
7g.99760870A>GCA456686473CYP3A4c.1458T>C (p.Ala486=)
n.800T>C
c.1365T>C (p.Ala455=)
c.906T>C (p.Ala302=)
c.1218T>C (p.Ala406=)
c.915T>C (p.Ala305=)
c.1362T>C (p.Ala454=)
c.1455T>C (p.Ala485=)
7g.99760870A>TCA456686474CYP3A4c.1458T>A (p.Ala486=)
n.800T>A
c.1365T>A (p.Ala455=)
c.906T>A (p.Ala302=)
c.1218T>A (p.Ala406=)
c.915T>A (p.Ala305=)
c.1362T>A (p.Ala454=)
c.1455T>A (p.Ala485=)
7g.99760871G>ACA368367718CYP3A4c.1457C>T (p.Ala486Val)
n.799C>T
c.1364C>T (p.Ala455Val)
c.905C>T (p.Ala302Val)
c.1217C>T (p.Ala406Val)
c.914C>T (p.Ala305Val)
c.1361C>T (p.Ala454Val)
c.1454C>T (p.Ala485Val)
7g.99760871G>CCA368367716CYP3A4c.1457C>G (p.Ala486Gly)
n.799C>G
c.1364C>G (p.Ala455Gly)
c.905C>G (p.Ala302Gly)
c.1217C>G (p.Ala406Gly)
c.914C>G (p.Ala305Gly)
c.1361C>G (p.Ala454Gly)
c.1454C>G (p.Ala485Gly)
7g.99760871G>TCA368367714CYP3A4c.1457C>A (p.Ala486Asp)
n.799C>A
c.1364C>A (p.Ala455Asp)
c.905C>A (p.Ala302Asp)
c.1217C>A (p.Ala406Asp)
c.914C>A (p.Ala305Asp)
c.1361C>A (p.Ala454Asp)
c.1454C>A (p.Ala485Asp)
7g.99760872C>ACA368367719CYP3A4c.1456G>T (p.Ala486Ser)
n.798G>T
c.1363G>T (p.Ala455Ser)
c.904G>T (p.Ala302Ser)
c.1216G>T (p.Ala406Ser)
c.913G>T (p.Ala305Ser)
c.1360G>T (p.Ala454Ser)
c.1453G>T (p.Ala485Ser)
 dbSNP
7g.99760872C=CA1729176752CYP3A4c.1456G= (p.Ala486=)
n.798G=
c.1363G= (p.Ala455=)
c.904G= (p.Ala302=)
c.1216G= (p.Ala406=)
c.913G= (p.Ala305=)
c.1360G= (p.Ala454=)
c.1453G= (p.Ala485=)
7g.99760872C>GCA368367721CYP3A4c.1456G>C (p.Ala486Pro)
n.798G>C
c.1363G>C (p.Ala455Pro)
c.904G>C (p.Ala302Pro)
c.1216G>C (p.Ala406Pro)
c.913G>C (p.Ala305Pro)
c.1360G>C (p.Ala454Pro)
c.1453G>C (p.Ala485Pro)
7g.99760872C>TCA368367723CYP3A4c.1456G>A (p.Ala486Thr)
n.798G>A
c.1363G>A (p.Ala455Thr)
c.904G>A (p.Ala302Thr)
c.1216G>A (p.Ala406Thr)
c.913G>A (p.Ala305Thr)
c.1360G>A (p.Ala454Thr)
c.1453G>A (p.Ala485Thr)
7g.99760873A>CCA456686476CYP3A4c.1455T>G (p.Leu485=)
n.797T>G
c.1362T>G (p.Leu454=)
c.903T>G (p.Leu301=)
c.1215T>G (p.Leu405=)
c.912T>G (p.Leu304=)
c.1359T>G (p.Leu453=)
c.1452T>G (p.Leu484=)
7g.99760873A>GCA456686478CYP3A4c.1455T>C (p.Leu485=)
n.797T>C
c.1362T>C (p.Leu454=)
c.903T>C (p.Leu301=)
c.1215T>C (p.Leu405=)
c.912T>C (p.Leu304=)
c.1359T>C (p.Leu453=)
c.1452T>C (p.Leu484=)
7g.99760873A>TCA456686477CYP3A4c.1455T>A (p.Leu485=)
n.797T>A
c.1362T>A (p.Leu454=)
c.903T>A (p.Leu301=)
c.1215T>A (p.Leu405=)
c.912T>A (p.Leu304=)
c.1359T>A (p.Leu453=)
c.1452T>A (p.Leu484=)
7g.99760874A=CA1729176753CYP3A4c.1454T= (p.Leu485=)
n.796T=
c.1361T= (p.Leu454=)
c.902T= (p.Leu301=)
c.1214T= (p.Leu405=)
c.911T= (p.Leu304=)
c.1358T= (p.Leu453=)
c.1451T= (p.Leu484=)
7g.99760874A>CCA368367725CYP3A4c.1454T>G (p.Leu485Arg)
n.796T>G
c.1361T>G (p.Leu454Arg)
c.902T>G (p.Leu301Arg)
c.1214T>G (p.Leu405Arg)
c.911T>G (p.Leu304Arg)
c.1358T>G (p.Leu453Arg)
c.1451T>G (p.Leu484Arg)
7g.99760874A>GCA4369489CYP3A4c.1454T>C (p.Leu485Pro)
n.796T>C
c.1361T>C (p.Leu454Pro)
c.902T>C (p.Leu301Pro)
c.1214T>C (p.Leu405Pro)
c.911T>C (p.Leu304Pro)
c.1358T>C (p.Leu453Pro)
c.1451T>C (p.Leu484Pro)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760874A>TCA368367727CYP3A4c.1454T>A (p.Leu485His)
n.796T>A
c.1361T>A (p.Leu454His)
c.902T>A (p.Leu301His)
c.1214T>A (p.Leu405His)
c.911T>A (p.Leu304His)
c.1358T>A (p.Leu453His)
c.1451T>A (p.Leu484His)
7g.99760874_99760875delinsAGCA1729176754CYP3A4c.1453_1454delinsCT (p.Leu485=)
n.795_796delinsCT
c.1360_1361delinsCT (p.Leu454=)
c.901_902delinsCT (p.Leu301=)
c.1213_1214delinsCT (p.Leu405=)
c.910_911delinsCT (p.Leu304=)
c.1357_1358delinsCT (p.Leu453=)
c.1450_1451delinsCT (p.Leu484=)
7g.99760875delCA918084481CYP3A4c.1453del (p.Ala486LeufsTer2)
n.795del
c.1360del (p.Ala455LeufsTer2)
c.901del (p.Ala302LeufsTer2)
c.1213del (p.Ala406LeufsTer2)
c.910del (p.Ala305LeufsTer2)
c.1357del (p.Ala454LeufsTer2)
c.1450del (p.Ala485LeufsTer2)
 dbSNP
7g.99760875G>ACA163151123CYP3A4c.1453C>T (p.Leu485Phe)
n.795C>T
c.1360C>T (p.Leu454Phe)
c.901C>T (p.Leu301Phe)
c.1213C>T (p.Leu405Phe)
c.910C>T (p.Leu304Phe)
c.1357C>T (p.Leu453Phe)
c.1450C>T (p.Leu484Phe)
 dbSNP
7g.99760875G>CCA368367730CYP3A4c.1453C>G (p.Leu485Val)
n.795C>G
c.1360C>G (p.Leu454Val)
c.901C>G (p.Leu301Val)
c.1213C>G (p.Leu405Val)
c.910C>G (p.Leu304Val)
c.1357C>G (p.Leu453Val)
c.1450C>G (p.Leu484Val)
7g.99760875G=CA1729176755CYP3A4c.1453C= (p.Leu485=)
n.795C=
c.1360C= (p.Leu454=)
c.901C= (p.Leu301=)
c.1213C= (p.Leu405=)
c.910C= (p.Leu304=)
c.1357C= (p.Leu453=)
c.1450C= (p.Leu484=)
7g.99760875G>TCA368367732CYP3A4c.1453C>A (p.Leu485Ile)
n.795C>A
c.1360C>A (p.Leu454Ile)
c.901C>A (p.Leu301Ile)
c.1213C>A (p.Leu405Ile)
c.910C>A (p.Leu304Ile)
c.1357C>A (p.Leu453Ile)
c.1450C>A (p.Leu484Ile)
 dbSNP
7g.99760876T>ACA368367733CYP3A4c.1452A>T (p.Lys484Asn)
n.794A>T
c.1359A>T (p.Lys453Asn)
c.900A>T (p.Lys300Asn)
c.1212A>T (p.Lys404Asn)
c.909A>T (p.Lys303Asn)
c.1356A>T (p.Lys452Asn)
c.1449A>T (p.Lys483Asn)
7g.99760876T>CCA456686481CYP3A4c.1452A>G (p.Lys484=)
n.794A>G
c.1359A>G (p.Lys453=)
c.900A>G (p.Lys300=)
c.1212A>G (p.Lys404=)
c.909A>G (p.Lys303=)
c.1356A>G (p.Lys452=)
c.1449A>G (p.Lys483=)
7g.99760876T>GCA4369491CYP3A4c.1452A>C (p.Lys484Asn)
n.794A>C
c.1359A>C (p.Lys453Asn)
c.900A>C (p.Lys300Asn)
c.1212A>C (p.Lys404Asn)
c.909A>C (p.Lys303Asn)
c.1356A>C (p.Lys452Asn)
c.1449A>C (p.Lys483Asn)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760876T=CA1729176756CYP3A4c.1452A= (p.Lys484=)
n.794A=
c.1359A= (p.Lys453=)
c.900A= (p.Lys300=)
c.1212A= (p.Lys404=)
c.909A= (p.Lys303=)
c.1356A= (p.Lys452=)
c.1449A= (p.Lys483=)
7g.99760878dupCA4369490CYP3A4c.1452dup (p.Leu485ThrfsTer16)
n.794dup
c.1359dup (p.Leu454ThrfsTer16)
c.900dup (p.Leu301ThrfsTer16)
c.1212dup (p.Leu405ThrfsTer16)
c.909dup (p.Leu304ThrfsTer16)
c.1356dup (p.Leu453ThrfsTer16)
c.1449dup (p.Leu484ThrfsTer16)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760877T>ACA368367735CYP3A4c.1451A>T (p.Lys484Ile)
n.793A>T
c.1358A>T (p.Lys453Ile)
c.899A>T (p.Lys300Ile)
c.1211A>T (p.Lys404Ile)
c.908A>T (p.Lys303Ile)
c.1355A>T (p.Lys452Ile)
c.1448A>T (p.Lys483Ile)
7g.99760877T>CCA368367737CYP3A4c.1451A>G (p.Lys484Arg)
n.793A>G
c.1358A>G (p.Lys453Arg)
c.899A>G (p.Lys300Arg)
c.1211A>G (p.Lys404Arg)
c.908A>G (p.Lys303Arg)
c.1355A>G (p.Lys452Arg)
c.1448A>G (p.Lys483Arg)
7g.99760877T>GCA368367736CYP3A4c.1451A>C (p.Lys484Thr)
n.793A>C
c.1358A>C (p.Lys453Thr)
c.899A>C (p.Lys300Thr)
c.1211A>C (p.Lys404Thr)
c.908A>C (p.Lys303Thr)
c.1355A>C (p.Lys452Thr)
c.1448A>C (p.Lys483Thr)
7g.99760878T>ACA368367740CYP3A4c.1450A>T (p.Lys484Ter)
n.792A>T
c.1357A>T (p.Lys453Ter)
c.898A>T (p.Lys300Ter)
c.1210A>T (p.Lys404Ter)
c.907A>T (p.Lys303Ter)
c.1354A>T (p.Lys452Ter)
c.1447A>T (p.Lys483Ter)
7g.99760878T>CCA368367742CYP3A4c.1450A>G (p.Lys484Glu)
n.792A>G
c.1357A>G (p.Lys453Glu)
c.898A>G (p.Lys300Glu)
c.1210A>G (p.Lys404Glu)
c.907A>G (p.Lys303Glu)
c.1354A>G (p.Lys452Glu)
c.1447A>G (p.Lys483Glu)
7g.99760878T>GCA368367743CYP3A4c.1450A>C (p.Lys484Gln)
n.792A>C
c.1357A>C (p.Lys453Gln)
c.898A>C (p.Lys300Gln)
c.1210A>C (p.Lys404Gln)
c.907A>C (p.Lys303Gln)
c.1354A>C (p.Lys452Gln)
c.1447A>C (p.Lys483Gln)
7g.99760879C>ACA368367746CYP3A4c.1449G>T (p.Met483Ile)
n.791G>T
c.1356G>T (p.Met452Ile)
c.897G>T (p.Met299Ile)
c.1209G>T (p.Met403Ile)
c.906G>T (p.Met302Ile)
c.1353G>T (p.Met451Ile)
c.1446G>T (p.Met482Ile)
 COSMIC
7g.99760879C>GCA368367748CYP3A4c.1449G>C (p.Met483Ile)
n.791G>C
c.1356G>C (p.Met452Ile)
c.897G>C (p.Met299Ile)
c.1209G>C (p.Met403Ile)
c.906G>C (p.Met302Ile)
c.1353G>C (p.Met451Ile)
c.1446G>C (p.Met482Ile)
7g.99760879C>TCA368367749CYP3A4c.1449G>A (p.Met483Ile)
n.791G>A
c.1356G>A (p.Met452Ile)
c.897G>A (p.Met299Ile)
c.1209G>A (p.Met403Ile)
c.906G>A (p.Met302Ile)
c.1353G>A (p.Met451Ile)
c.1446G>A (p.Met482Ile)
 COSMIC
7g.99760880A=CA1729176757CYP3A4c.1448T= (p.Met483=)
n.790T=
c.1355T= (p.Met452=)
c.896T= (p.Met299=)
c.1208T= (p.Met403=)
c.905T= (p.Met302=)
c.1352T= (p.Met451=)
c.1445T= (p.Met482=)
7g.99760880A>CCA368367753CYP3A4c.1448T>G (p.Met483Arg)
n.790T>G
c.1355T>G (p.Met452Arg)
c.896T>G (p.Met299Arg)
c.1208T>G (p.Met403Arg)
c.905T>G (p.Met302Arg)
c.1352T>G (p.Met451Arg)
c.1445T>G (p.Met482Arg)
7g.99760880A>GCA4369492CYP3A4c.1448T>C (p.Met483Thr)
n.790T>C
c.1355T>C (p.Met452Thr)
c.896T>C (p.Met299Thr)
c.1208T>C (p.Met403Thr)
c.905T>C (p.Met302Thr)
c.1352T>C (p.Met451Thr)
c.1445T>C (p.Met482Thr)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760880A>TCA368367751CYP3A4c.1448T>A (p.Met483Lys)
n.790T>A
c.1355T>A (p.Met452Lys)
c.896T>A (p.Met299Lys)
c.1208T>A (p.Met403Lys)
c.905T>A (p.Met302Lys)
c.1352T>A (p.Met451Lys)
c.1445T>A (p.Met482Lys)
7g.99760881T>ACA4369493CYP3A4c.1447A>T (p.Met483Leu)
n.789A>T
c.1354A>T (p.Met452Leu)
c.895A>T (p.Met299Leu)
c.1207A>T (p.Met403Leu)
c.904A>T (p.Met302Leu)
c.1351A>T (p.Met451Leu)
c.1444A>T (p.Met482Leu)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760881T>CCA368368551CYP3A4c.1447A>G (p.Met483Val)
n.789A>G
c.1354A>G (p.Met452Val)
c.895A>G (p.Met299Val)
c.1207A>G (p.Met403Val)
c.904A>G (p.Met302Val)
c.1351A>G (p.Met451Val)
c.1444A>G (p.Met482Val)
 dbSNP gnomAD v2 gnomAD v4 COSMIC
7g.99760881T>GCA368368552CYP3A4c.1447A>C (p.Met483Leu)
n.789A>C
c.1354A>C (p.Met452Leu)
c.895A>C (p.Met299Leu)
c.1207A>C (p.Met403Leu)
c.904A>C (p.Met302Leu)
c.1351A>C (p.Met451Leu)
c.1444A>C (p.Met482Leu)
7g.99760881T=CA1729176758CYP3A4c.1447A= (p.Met483=)
n.789A=
c.1354A= (p.Met452=)
c.895A= (p.Met299=)
c.1207A= (p.Met403=)
c.904A= (p.Met302=)
c.1351A= (p.Met451=)
c.1444A= (p.Met482=)
7g.99760882G>ACA4369494CYP3A4c.1446C>T (p.Asn482=)
n.788C>T
c.1353C>T (p.Asn451=)
c.894C>T (p.Asn298=)
c.1206C>T (p.Asn402=)
c.903C>T (p.Asn301=)
c.1350C>T (p.Asn450=)
c.1443C>T (p.Asn481=)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760882G>CCA368368553CYP3A4c.1446C>G (p.Asn482Lys)
n.788C>G
c.1353C>G (p.Asn451Lys)
c.894C>G (p.Asn298Lys)
c.1206C>G (p.Asn402Lys)
c.903C>G (p.Asn301Lys)
c.1350C>G (p.Asn450Lys)
c.1443C>G (p.Asn481Lys)
7g.99760882G=CA1729176759CYP3A4c.1446C= (p.Asn482=)
n.788C=
c.1353C= (p.Asn451=)
c.894C= (p.Asn298=)
c.1206C= (p.Asn402=)
c.903C= (p.Asn301=)
c.1350C= (p.Asn450=)
c.1443C= (p.Asn481=)
7g.99760882G>TCA368368554CYP3A4c.1446C>A (p.Asn482Lys)
n.788C>A
c.1353C>A (p.Asn451Lys)
c.894C>A (p.Asn298Lys)
c.1206C>A (p.Asn402Lys)
c.903C>A (p.Asn301Lys)
c.1350C>A (p.Asn450Lys)
c.1443C>A (p.Asn481Lys)
7g.99760883T>ACA368368555CYP3A4c.1445A>T (p.Asn482Ile)
n.787A>T
c.1352A>T (p.Asn451Ile)
c.893A>T (p.Asn298Ile)
c.1205A>T (p.Asn402Ile)
c.902A>T (p.Asn301Ile)
c.1349A>T (p.Asn450Ile)
c.1442A>T (p.Asn481Ile)
7g.99760883T>CCA368368557CYP3A4c.1445A>G (p.Asn482Ser)
n.787A>G
c.1352A>G (p.Asn451Ser)
c.893A>G (p.Asn298Ser)
c.1205A>G (p.Asn402Ser)
c.902A>G (p.Asn301Ser)
c.1349A>G (p.Asn450Ser)
c.1442A>G (p.Asn481Ser)
 dbSNP gnomAD v4
7g.99760883T>GCA368368556CYP3A4c.1445A>C (p.Asn482Thr)
n.787A>C
c.1352A>C (p.Asn451Thr)
c.893A>C (p.Asn298Thr)
c.1205A>C (p.Asn402Thr)
c.902A>C (p.Asn301Thr)
c.1349A>C (p.Asn450Thr)
c.1442A>C (p.Asn481Thr)
 gnomAD v4
7g.99760883T=CA1729176760CYP3A4c.1445A= (p.Asn482=)
n.787A=
c.1352A= (p.Asn451=)
c.893A= (p.Asn298=)
c.1205A= (p.Asn402=)
c.902A= (p.Asn301=)
c.1349A= (p.Asn450=)
c.1442A= (p.Asn481=)
7g.99760884T>ACA368368558CYP3A4c.1444A>T (p.Asn482Tyr)
n.786A>T
c.1351A>T (p.Asn451Tyr)
c.892A>T (p.Asn298Tyr)
c.1204A>T (p.Asn402Tyr)
c.901A>T (p.Asn301Tyr)
c.1348A>T (p.Asn450Tyr)
c.1441A>T (p.Asn481Tyr)
7g.99760884T>CCA368368559CYP3A4c.1444A>G (p.Asn482Asp)
n.786A>G
c.1351A>G (p.Asn451Asp)
c.892A>G (p.Asn298Asp)
c.1204A>G (p.Asn402Asp)
c.901A>G (p.Asn301Asp)
c.1348A>G (p.Asn450Asp)
c.1441A>G (p.Asn481Asp)
7g.99760884T>GCA368368560CYP3A4c.1444A>C (p.Asn482His)
n.786A>C
c.1351A>C (p.Asn451His)
c.892A>C (p.Asn298His)
c.1204A>C (p.Asn402His)
c.901A>C (p.Asn301His)
c.1348A>C (p.Asn450His)
c.1441A>C (p.Asn481His)
7g.99760885C>ACA368368561CYP3A4c.1443G>T (p.Met481Ile)
n.785G>T
c.1350G>T (p.Met450Ile)
c.891G>T (p.Met297Ile)
c.1203G>T (p.Met401Ile)
c.900G>T (p.Met300Ile)
c.1347G>T (p.Met449Ile)
c.1440G>T (p.Met480Ile)
7g.99760885C>GCA368368562CYP3A4c.1443G>C (p.Met481Ile)
n.785G>C
c.1350G>C (p.Met450Ile)
c.891G>C (p.Met297Ile)
c.1203G>C (p.Met401Ile)
c.900G>C (p.Met300Ile)
c.1347G>C (p.Met449Ile)
c.1440G>C (p.Met480Ile)
7g.99760885C>TCA368368563CYP3A4c.1443G>A (p.Met481Ile)
n.785G>A
c.1350G>A (p.Met450Ile)
c.891G>A (p.Met297Ile)
c.1203G>A (p.Met401Ile)
c.900G>A (p.Met300Ile)
c.1347G>A (p.Met449Ile)
c.1440G>A (p.Met480Ile)
 dbSNP
7g.99760886A=CA1729176761CYP3A4c.1442T= (p.Met481=)
n.784T=
c.1349T= (p.Met450=)
c.890T= (p.Met297=)
c.1202T= (p.Met401=)
c.899T= (p.Met300=)
c.1346T= (p.Met449=)
c.1439T= (p.Met480=)
7g.99760886A>CCA368368564CYP3A4c.1442T>G (p.Met481Arg)
n.784T>G
c.1349T>G (p.Met450Arg)
c.890T>G (p.Met297Arg)
c.1202T>G (p.Met401Arg)
c.899T>G (p.Met300Arg)
c.1346T>G (p.Met449Arg)
c.1439T>G (p.Met480Arg)
7g.99760886A>GCA4369495CYP3A4c.1442T>C (p.Met481Thr)
n.784T>C
c.1349T>C (p.Met450Thr)
c.890T>C (p.Met297Thr)
c.1202T>C (p.Met401Thr)
c.899T>C (p.Met300Thr)
c.1346T>C (p.Met449Thr)
c.1439T>C (p.Met480Thr)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760886A>TCA368368565CYP3A4c.1442T>A (p.Met481Lys)
n.784T>A
c.1349T>A (p.Met450Lys)
c.890T>A (p.Met297Lys)
c.1202T>A (p.Met401Lys)
c.899T>A (p.Met300Lys)
c.1346T>A (p.Met449Lys)
c.1439T>A (p.Met480Lys)
7g.99760887T>ACA368368566CYP3A4c.1441A>T (p.Met481Leu)
n.783A>T
c.1348A>T (p.Met450Leu)
c.889A>T (p.Met297Leu)
c.1201A>T (p.Met401Leu)
c.898A>T (p.Met300Leu)
c.1345A>T (p.Met449Leu)
c.1438A>T (p.Met480Leu)
7g.99760887T>CCA4369496CYP3A4c.1441A>G (p.Met481Val)
n.783A>G
c.1348A>G (p.Met450Val)
c.889A>G (p.Met297Val)
c.1201A>G (p.Met401Val)
c.898A>G (p.Met300Val)
c.1345A>G (p.Met449Val)
c.1438A>G (p.Met480Val)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760887T>GCA368368567CYP3A4c.1441A>C (p.Met481Leu)
n.783A>C
c.1348A>C (p.Met450Leu)
c.889A>C (p.Met297Leu)
c.1201A>C (p.Met401Leu)
c.898A>C (p.Met300Leu)
c.1345A>C (p.Met449Leu)
c.1438A>C (p.Met480Leu)
 gnomAD v3 gnomAD v4
7g.99760887T=CA1729176762CYP3A4c.1441A= (p.Met481=)
n.783A=
c.1348A= (p.Met450=)
c.889A= (p.Met297=)
c.1201A= (p.Met401=)
c.898A= (p.Met300=)
c.1345A= (p.Met449=)
c.1438A= (p.Met480=)
7g.99760888G>ACA456686586CYP3A4c.1440C>T (p.Leu480=)
n.782C>T
c.1347C>T (p.Leu449=)
c.888C>T (p.Leu296=)
c.1200C>T (p.Leu400=)
c.897C>T (p.Leu299=)
c.1344C>T (p.Leu448=)
c.1437C>T (p.Leu479=)
7g.99760888G>CCA456686587CYP3A4c.1440C>G (p.Leu480=)
n.782C>G
c.1347C>G (p.Leu449=)
c.888C>G (p.Leu296=)
c.1200C>G (p.Leu400=)
c.897C>G (p.Leu299=)
c.1344C>G (p.Leu448=)
c.1437C>G (p.Leu479=)
7g.99760888G>TCA456686588CYP3A4c.1440C>A (p.Leu480=)
n.782C>A
c.1347C>A (p.Leu449=)
c.888C>A (p.Leu296=)
c.1200C>A (p.Leu400=)
c.897C>A (p.Leu299=)
c.1344C>A (p.Leu448=)
c.1437C>A (p.Leu479=)
7g.99760889A>CCA368368568CYP3A4c.1439T>G (p.Leu480Arg)
n.781T>G
c.1346T>G (p.Leu449Arg)
c.887T>G (p.Leu296Arg)
c.1199T>G (p.Leu400Arg)
c.896T>G (p.Leu299Arg)
c.1343T>G (p.Leu448Arg)
c.1436T>G (p.Leu479Arg)
7g.99760889A>GCA368368570CYP3A4c.1439T>C (p.Leu480Pro)
n.781T>C
c.1346T>C (p.Leu449Pro)
c.887T>C (p.Leu296Pro)
c.1199T>C (p.Leu400Pro)
c.896T>C (p.Leu299Pro)
c.1343T>C (p.Leu448Pro)
c.1436T>C (p.Leu479Pro)
 gnomAD v4
7g.99760889A>TCA368368569CYP3A4c.1439T>A (p.Leu480His)
n.781T>A
c.1346T>A (p.Leu449His)
c.887T>A (p.Leu296His)
c.1199T>A (p.Leu400His)
c.896T>A (p.Leu299His)
c.1343T>A (p.Leu448His)
c.1436T>A (p.Leu479His)
7g.99760890G>ACA4369497CYP3A4c.1438C>T (p.Leu480Phe)
n.780C>T
c.1345C>T (p.Leu449Phe)
c.886C>T (p.Leu296Phe)
c.1198C>T (p.Leu400Phe)
c.895C>T (p.Leu299Phe)
c.1342C>T (p.Leu448Phe)
c.1435C>T (p.Leu479Phe)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760890G>CCA368368571CYP3A4c.1438C>G (p.Leu480Val)
n.780C>G
c.1345C>G (p.Leu449Val)
c.886C>G (p.Leu296Val)
c.1198C>G (p.Leu400Val)
c.895C>G (p.Leu299Val)
c.1342C>G (p.Leu448Val)
c.1435C>G (p.Leu479Val)
7g.99760890G=CA1729176763CYP3A4c.1438C= (p.Leu480=)
n.780C=
c.1345C= (p.Leu449=)
c.886C= (p.Leu296=)
c.1198C= (p.Leu400=)
c.895C= (p.Leu299=)
c.1342C= (p.Leu448=)
c.1435C= (p.Leu479=)
7g.99760890G>TCA368368572CYP3A4c.1438C>A (p.Leu480Ile)
n.780C>A
c.1345C>A (p.Leu449Ile)
c.886C>A (p.Leu296Ile)
c.1198C>A (p.Leu400Ile)
c.895C>A (p.Leu299Ile)
c.1342C>A (p.Leu448Ile)
c.1435C>A (p.Leu479Ile)
7g.99760891A=CA1729176764CYP3A4c.1437T= (p.Ala479=)
n.779T=
c.1344T= (p.Ala448=)
c.885T= (p.Ala295=)
c.1197T= (p.Ala399=)
c.894T= (p.Ala298=)
c.1341T= (p.Ala447=)
c.1434T= (p.Ala478=)
7g.99760891A>CCA456686592CYP3A4c.1437T>G (p.Ala479=)
n.779T>G
c.1344T>G (p.Ala448=)
c.885T>G (p.Ala295=)
c.1197T>G (p.Ala399=)
c.894T>G (p.Ala298=)
c.1341T>G (p.Ala447=)
c.1434T>G (p.Ala478=)
7g.99760891A>GCA456686593CYP3A4c.1437T>C (p.Ala479=)
n.779T>C
c.1344T>C (p.Ala448=)
c.885T>C (p.Ala295=)
c.1197T>C (p.Ala399=)
c.894T>C (p.Ala298=)
c.1341T>C (p.Ala447=)
c.1434T>C (p.Ala478=)
 dbSNP gnomAD v3 gnomAD v4
7g.99760891A>TCA456686594CYP3A4c.1437T>A (p.Ala479=)
n.779T>A
c.1344T>A (p.Ala448=)
c.885T>A (p.Ala295=)
c.1197T>A (p.Ala399=)
c.894T>A (p.Ala298=)
c.1341T>A (p.Ala447=)
c.1434T>A (p.Ala478=)
7g.99760892G>ACA368368573CYP3A4c.1436C>T (p.Ala479Val)
n.778C>T
c.1343C>T (p.Ala448Val)
c.884C>T (p.Ala295Val)
c.1196C>T (p.Ala399Val)
c.893C>T (p.Ala298Val)
c.1340C>T (p.Ala447Val)
c.1433C>T (p.Ala478Val)
 dbSNP
7g.99760892G>CCA368368574CYP3A4c.1436C>G (p.Ala479Gly)
n.778C>G
c.1343C>G (p.Ala448Gly)
c.884C>G (p.Ala295Gly)
c.1196C>G (p.Ala399Gly)
c.893C>G (p.Ala298Gly)
c.1340C>G (p.Ala447Gly)
c.1433C>G (p.Ala478Gly)
7g.99760892G>TCA368368575CYP3A4c.1436C>A (p.Ala479Asp)
n.778C>A
c.1343C>A (p.Ala448Asp)
c.884C>A (p.Ala295Asp)
c.1196C>A (p.Ala399Asp)
c.893C>A (p.Ala298Asp)
c.1340C>A (p.Ala447Asp)
c.1433C>A (p.Ala478Asp)
7g.99760893C>ACA368368578CYP3A4c.1435G>T (p.Ala479Ser)
n.777G>T
c.1342G>T (p.Ala448Ser)
c.883G>T (p.Ala295Ser)
c.1195G>T (p.Ala399Ser)
c.892G>T (p.Ala298Ser)
c.1339G>T (p.Ala447Ser)
c.1432G>T (p.Ala478Ser)
 dbSNP
7g.99760893C=CA1729176765CYP3A4c.1435G= (p.Ala479=)
n.777G=
c.1342G= (p.Ala448=)
c.883G= (p.Ala295=)
c.1195G= (p.Ala399=)
c.892G= (p.Ala298=)
c.1339G= (p.Ala447=)
c.1432G= (p.Ala478=)
7g.99760893C>GCA368368576CYP3A4c.1435G>C (p.Ala479Pro)
n.777G>C
c.1342G>C (p.Ala448Pro)
c.883G>C (p.Ala295Pro)
c.1195G>C (p.Ala399Pro)
c.892G>C (p.Ala298Pro)
c.1339G>C (p.Ala447Pro)
c.1432G>C (p.Ala478Pro)
7g.99760893C>TCA368368577CYP3A4c.1435G>A (p.Ala479Thr)
n.777G>A
c.1342G>A (p.Ala448Thr)
c.883G>A (p.Ala295Thr)
c.1195G>A (p.Ala399Thr)
c.892G>A (p.Ala298Thr)
c.1339G>A (p.Ala447Thr)
c.1432G>A (p.Ala478Thr)
7g.99760894A=CA1729176766CYP3A4c.1434T= (p.Phe478=)
n.776T=
c.1341T= (p.Phe447=)
c.882T= (p.Phe294=)
c.1194T= (p.Phe398=)
c.891T= (p.Phe297=)
c.1338T= (p.Phe446=)
c.1431T= (p.Phe477=)
7g.99760894A>CCA368368579CYP3A4c.1434T>G (p.Phe478Leu)
n.776T>G
c.1341T>G (p.Phe447Leu)
c.882T>G (p.Phe294Leu)
c.1194T>G (p.Phe398Leu)
c.891T>G (p.Phe297Leu)
c.1338T>G (p.Phe446Leu)
c.1431T>G (p.Phe477Leu)
7g.99760894A>GCA456686596CYP3A4c.1434T>C (p.Phe478=)
n.776T>C
c.1341T>C (p.Phe447=)
c.882T>C (p.Phe294=)
c.1194T>C (p.Phe398=)
c.891T>C (p.Phe297=)
c.1338T>C (p.Phe446=)
c.1431T>C (p.Phe477=)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
7g.99760894A>TCA368368580CYP3A4c.1434T>A (p.Phe478Leu)
n.776T>A
c.1341T>A (p.Phe447Leu)
c.882T>A (p.Phe294Leu)
c.1194T>A (p.Phe398Leu)
c.891T>A (p.Phe297Leu)
c.1338T>A (p.Phe446Leu)
c.1431T>A (p.Phe477Leu)
7g.99760895A>CCA368368581CYP3A4c.1433T>G (p.Phe478Cys)
n.775T>G
c.1340T>G (p.Phe447Cys)
c.881T>G (p.Phe294Cys)
c.1193T>G (p.Phe398Cys)
c.890T>G (p.Phe297Cys)
c.1337T>G (p.Phe446Cys)
c.1430T>G (p.Phe477Cys)
7g.99760895A>GCA368368582CYP3A4c.1433T>C (p.Phe478Ser)
n.775T>C
c.1340T>C (p.Phe447Ser)
c.881T>C (p.Phe294Ser)
c.1193T>C (p.Phe398Ser)
c.890T>C (p.Phe297Ser)
c.1337T>C (p.Phe446Ser)
c.1430T>C (p.Phe477Ser)
7g.99760895A>TCA368368583CYP3A4c.1433T>A (p.Phe478Tyr)
n.775T>A
c.1340T>A (p.Phe447Tyr)
c.881T>A (p.Phe294Tyr)
c.1193T>A (p.Phe398Tyr)
c.890T>A (p.Phe297Tyr)
c.1337T>A (p.Phe446Tyr)
c.1430T>A (p.Phe477Tyr)
7g.99760896A>CCA368368584CYP3A4c.1432T>G (p.Phe478Val)
n.774T>G
c.1339T>G (p.Phe447Val)
c.880T>G (p.Phe294Val)
c.1192T>G (p.Phe398Val)
c.889T>G (p.Phe297Val)
c.1336T>G (p.Phe446Val)
c.1429T>G (p.Phe477Val)
 gnomAD v4
7g.99760896A>GCA368368586CYP3A4c.1432T>C (p.Phe478Leu)
n.774T>C
c.1339T>C (p.Phe447Leu)
c.880T>C (p.Phe294Leu)
c.1192T>C (p.Phe398Leu)
c.889T>C (p.Phe297Leu)
c.1336T>C (p.Phe446Leu)
c.1429T>C (p.Phe477Leu)
7g.99760896A>TCA368368585CYP3A4c.1432T>A (p.Phe478Ile)
n.774T>A
c.1339T>A (p.Phe447Ile)
c.880T>A (p.Phe294Ile)
c.1192T>A (p.Phe398Ile)
c.889T>A (p.Phe297Ile)
c.1336T>A (p.Phe446Ile)
c.1429T>A (p.Phe477Ile)
7g.99760897C>ACA368368587CYP3A4c.1431G>T (p.Arg477Ser)
n.773G>T
c.1338G>T (p.Arg446Ser)
c.879G>T (p.Arg293Ser)
c.1191G>T (p.Arg397Ser)
c.888G>T (p.Arg296Ser)
c.1335G>T (p.Arg445Ser)
c.1428G>T (p.Arg476Ser)
 gnomAD v4
7g.99760897C>GCA368368588CYP3A4c.1431G>C (p.Arg477Ser)
n.773G>C
c.1338G>C (p.Arg446Ser)
c.879G>C (p.Arg293Ser)
c.1191G>C (p.Arg397Ser)
c.888G>C (p.Arg296Ser)
c.1335G>C (p.Arg445Ser)
c.1428G>C (p.Arg476Ser)
7g.99760897C>TCA456686598CYP3A4c.1431G>A (p.Arg477=)
n.773G>A
c.1338G>A (p.Arg446=)
c.879G>A (p.Arg293=)
c.1191G>A (p.Arg397=)
c.888G>A (p.Arg296=)
c.1335G>A (p.Arg445=)
c.1428G>A (p.Arg476=)
 gnomAD v4
7g.99760898C>ACA368368589CYP3A4c.1430G>T (p.Arg477Met)
n.772G>T
c.1337G>T (p.Arg446Met)
c.878G>T (p.Arg293Met)
c.1190G>T (p.Arg397Met)
c.887G>T (p.Arg296Met)
c.1334G>T (p.Arg445Met)
c.1427G>T (p.Arg476Met)
7g.99760898C=CA1729176767CYP3A4c.1430G= (p.Arg477=)
n.772G=
c.1337G= (p.Arg446=)
c.878G= (p.Arg293=)
c.1190G= (p.Arg397=)
c.887G= (p.Arg296=)
c.1334G= (p.Arg445=)
c.1427G= (p.Arg476=)
7g.99760898C>GCA368368590CYP3A4c.1430G>C (p.Arg477Thr)
n.772G>C
c.1337G>C (p.Arg446Thr)
c.878G>C (p.Arg293Thr)
c.1190G>C (p.Arg397Thr)
c.887G>C (p.Arg296Thr)
c.1334G>C (p.Arg445Thr)
c.1427G>C (p.Arg476Thr)
7g.99760898C>TCA163151140CYP3A4c.1430G>A (p.Arg477Lys)
n.772G>A
c.1337G>A (p.Arg446Lys)
c.878G>A (p.Arg293Lys)
c.1190G>A (p.Arg397Lys)
c.887G>A (p.Arg296Lys)
c.1334G>A (p.Arg445Lys)
c.1427G>A (p.Arg476Lys)
 dbSNP COSMIC
7g.99760899T>ACA368368591CYP3A4c.1429A>T (p.Arg477Trp)
n.771A>T
c.1336A>T (p.Arg446Trp)
c.877A>T (p.Arg293Trp)
c.1189A>T (p.Arg397Trp)
c.886A>T (p.Arg296Trp)
c.1333A>T (p.Arg445Trp)
c.1426A>T (p.Arg476Trp)
7g.99760899T>CCA368368592CYP3A4c.1429A>G (p.Arg477Gly)
n.771A>G
c.1336A>G (p.Arg446Gly)
c.877A>G (p.Arg293Gly)
c.1189A>G (p.Arg397Gly)
c.886A>G (p.Arg296Gly)
c.1333A>G (p.Arg445Gly)
c.1426A>G (p.Arg476Gly)
7g.99760899T>GCA456686602CYP3A4c.1429A>C (p.Arg477=)
n.771A>C
c.1336A>C (p.Arg446=)
c.877A>C (p.Arg293=)
c.1189A>C (p.Arg397=)
c.886A>C (p.Arg296=)
c.1333A>C (p.Arg445=)
c.1426A>C (p.Arg476=)
7g.99760900C>ACA368368593CYP3A4c.1428G>T (p.Met476Ile)
n.770G>T
c.1335G>T (p.Met445Ile)
c.876G>T (p.Met292Ile)
c.1188G>T (p.Met396Ile)
c.885G>T (p.Met295Ile)
c.1332G>T (p.Met444Ile)
c.1425G>T (p.Met475Ile)
7g.99760900C=CA1729176768CYP3A4c.1428G= (p.Met476=)
n.770G=
c.1335G= (p.Met445=)
c.876G= (p.Met292=)
c.1188G= (p.Met396=)
c.885G= (p.Met295=)
c.1332G= (p.Met444=)
c.1425G= (p.Met475=)
7g.99760900C>GCA368368594CYP3A4c.1428G>C (p.Met476Ile)
n.770G>C
c.1335G>C (p.Met445Ile)
c.876G>C (p.Met292Ile)
c.1188G>C (p.Met396Ile)
c.885G>C (p.Met295Ile)
c.1332G>C (p.Met444Ile)
c.1425G>C (p.Met475Ile)
 dbSNP gnomAD v2 gnomAD v4
7g.99760900C>TCA368368595CYP3A4c.1428G>A (p.Met476Ile)
n.770G>A
c.1335G>A (p.Met445Ile)
c.876G>A (p.Met292Ile)
c.1188G>A (p.Met396Ile)
c.885G>A (p.Met295Ile)
c.1332G>A (p.Met444Ile)
c.1425G>A (p.Met475Ile)
7g.99760901A=CA1729176769CYP3A4c.1427T= (p.Met476=)
n.769T=
c.1334T= (p.Met445=)
c.875T= (p.Met292=)
c.1187T= (p.Met396=)
c.884T= (p.Met295=)
c.1331T= (p.Met444=)
c.1424T= (p.Met475=)
7g.99760901A>CCA368368596CYP3A4c.1427T>G (p.Met476Arg)
n.769T>G
c.1334T>G (p.Met445Arg)
c.875T>G (p.Met292Arg)
c.1187T>G (p.Met396Arg)
c.884T>G (p.Met295Arg)
c.1331T>G (p.Met444Arg)
c.1424T>G (p.Met475Arg)
 gnomAD v3 gnomAD v4
7g.99760901A>GCA4369498CYP3A4c.1427T>C (p.Met476Thr)
n.769T>C
c.1334T>C (p.Met445Thr)
c.875T>C (p.Met292Thr)
c.1187T>C (p.Met396Thr)
c.884T>C (p.Met295Thr)
c.1331T>C (p.Met444Thr)
c.1424T>C (p.Met475Thr)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760901A>TCA368368597CYP3A4c.1427T>A (p.Met476Lys)
n.769T>A
c.1334T>A (p.Met445Lys)
c.875T>A (p.Met292Lys)
c.1187T>A (p.Met396Lys)
c.884T>A (p.Met295Lys)
c.1331T>A (p.Met444Lys)
c.1424T>A (p.Met475Lys)
7g.99760902T>ACA368368598CYP3A4c.1426A>T (p.Met476Leu)
n.768A>T
c.1333A>T (p.Met445Leu)
c.874A>T (p.Met292Leu)
c.1186A>T (p.Met396Leu)
c.883A>T (p.Met295Leu)
c.1330A>T (p.Met444Leu)
c.1423A>T (p.Met475Leu)
7g.99760902T>CCA368368600CYP3A4c.1426A>G (p.Met476Val)
n.768A>G
c.1333A>G (p.Met445Val)
c.874A>G (p.Met292Val)
c.1186A>G (p.Met396Val)
c.883A>G (p.Met295Val)
c.1330A>G (p.Met444Val)
c.1423A>G (p.Met475Val)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
7g.99760902T>GCA368368599CYP3A4c.1426A>C (p.Met476Leu)
n.768A>C
c.1333A>C (p.Met445Leu)
c.874A>C (p.Met292Leu)
c.1186A>C (p.Met396Leu)
c.883A>C (p.Met295Leu)
c.1330A>C (p.Met444Leu)
c.1423A>C (p.Met475Leu)
7g.99760902T=CA1729176770CYP3A4c.1426A= (p.Met476=)
n.768A=
c.1333A= (p.Met445=)
c.874A= (p.Met292=)
c.1186A= (p.Met396=)
c.883A= (p.Met295=)
c.1330A= (p.Met444=)
c.1423A= (p.Met475=)
7g.99760903G>ACA456686603CYP3A4c.1425C>T (p.Gly475=)
n.767C>T
c.1332C>T (p.Gly444=)
c.873C>T (p.Gly291=)
c.1185C>T (p.Gly395=)
c.882C>T (p.Gly294=)
c.1329C>T (p.Gly443=)
c.1422C>T (p.Gly474=)
7g.99760903G>CCA456686604CYP3A4c.1425C>G (p.Gly475=)
n.767C>G
c.1332C>G (p.Gly444=)
c.873C>G (p.Gly291=)
c.1185C>G (p.Gly395=)
c.882C>G (p.Gly294=)
c.1329C>G (p.Gly443=)
c.1422C>G (p.Gly474=)
7g.99760903G>TCA456686605CYP3A4c.1425C>A (p.Gly475=)
n.767C>A
c.1332C>A (p.Gly444=)
c.873C>A (p.Gly291=)
c.1185C>A (p.Gly395=)
c.882C>A (p.Gly294=)
c.1329C>A (p.Gly443=)
c.1422C>A (p.Gly474=)
7g.99760904C>ACA368368601CYP3A4c.1424G>T (p.Gly475Val)
n.766G>T
c.1331G>T (p.Gly444Val)
c.872G>T (p.Gly291Val)
c.1184G>T (p.Gly395Val)
c.881G>T (p.Gly294Val)
c.1328G>T (p.Gly443Val)
c.1421G>T (p.Gly474Val)
7g.99760904C=CA1729176771CYP3A4c.1424G= (p.Gly475=)
n.766G=
c.1331G= (p.Gly444=)
c.872G= (p.Gly291=)
c.1184G= (p.Gly395=)
c.881G= (p.Gly294=)
c.1328G= (p.Gly443=)
c.1421G= (p.Gly474=)
7g.99760904C>GCA368368603CYP3A4c.1424G>C (p.Gly475Ala)
n.766G>C
c.1331G>C (p.Gly444Ala)
c.872G>C (p.Gly291Ala)
c.1184G>C (p.Gly395Ala)
c.881G>C (p.Gly294Ala)
c.1328G>C (p.Gly443Ala)
c.1421G>C (p.Gly474Ala)
 dbSNP gnomAD v2 gnomAD v4
7g.99760904C>TCA368368602CYP3A4c.1424G>A (p.Gly475Asp)
n.766G>A
c.1331G>A (p.Gly444Asp)
c.872G>A (p.Gly291Asp)
c.1184G>A (p.Gly395Asp)
c.881G>A (p.Gly294Asp)
c.1328G>A (p.Gly443Asp)
c.1421G>A (p.Gly474Asp)
 dbSNP gnomAD v3 gnomAD v4
7g.99760905C>ACA368368604CYP3A4c.1423G>T (p.Gly475Cys)
n.765G>T
c.1330G>T (p.Gly444Cys)
c.871G>T (p.Gly291Cys)
c.1183G>T (p.Gly395Cys)
c.880G>T (p.Gly294Cys)
c.1327G>T (p.Gly443Cys)
c.1420G>T (p.Gly474Cys)
7g.99760905C>GCA368368605CYP3A4c.1423G>C (p.Gly475Arg)
n.765G>C
c.1330G>C (p.Gly444Arg)
c.871G>C (p.Gly291Arg)
c.1183G>C (p.Gly395Arg)
c.880G>C (p.Gly294Arg)
c.1327G>C (p.Gly443Arg)
c.1420G>C (p.Gly474Arg)
7g.99760905C>TCA368368606CYP3A4c.1423G>A (p.Gly475Ser)
n.765G>A
c.1330G>A (p.Gly444Ser)
c.871G>A (p.Gly291Ser)
c.1183G>A (p.Gly395Ser)
c.880G>A (p.Gly294Ser)
c.1327G>A (p.Gly443Ser)
c.1420G>A (p.Gly474Ser)
7g.99760906A>CCA368368607CYP3A4c.1422T>G (p.Ile474Met)
n.764T>G
c.1329T>G (p.Ile443Met)
c.870T>G (p.Ile290Met)
c.1182T>G (p.Ile394Met)
c.879T>G (p.Ile293Met)
c.1326T>G (p.Ile442Met)
c.1419T>G (p.Ile473Met)
7g.99760906A>GCA456686606CYP3A4c.1422T>C (p.Ile474=)
n.764T>C
c.1329T>C (p.Ile443=)
c.870T>C (p.Ile290=)
c.1182T>C (p.Ile394=)
c.879T>C (p.Ile293=)
c.1326T>C (p.Ile442=)
c.1419T>C (p.Ile473=)
7g.99760906A>TCA456686607CYP3A4c.1422T>A (p.Ile474=)
n.764T>A
c.1329T>A (p.Ile443=)
c.870T>A (p.Ile290=)
c.1182T>A (p.Ile394=)
c.879T>A (p.Ile293=)
c.1326T>A (p.Ile442=)
c.1419T>A (p.Ile473=)
7g.99760907A>CCA368368608CYP3A4c.1421T>G (p.Ile474Ser)
n.763T>G
c.1328T>G (p.Ile443Ser)
c.869T>G (p.Ile290Ser)
c.1181T>G (p.Ile394Ser)
c.878T>G (p.Ile293Ser)
c.1325T>G (p.Ile442Ser)
c.1418T>G (p.Ile473Ser)
7g.99760907A>GCA368368609CYP3A4c.1421T>C (p.Ile474Thr)
n.763T>C
c.1328T>C (p.Ile443Thr)
c.869T>C (p.Ile290Thr)
c.1181T>C (p.Ile394Thr)
c.878T>C (p.Ile293Thr)
c.1325T>C (p.Ile442Thr)
c.1418T>C (p.Ile473Thr)
 gnomAD v3 gnomAD v4
7g.99760907A>TCA368368610CYP3A4c.1421T>A (p.Ile474Asn)
n.763T>A
c.1328T>A (p.Ile443Asn)
c.869T>A (p.Ile290Asn)
c.1181T>A (p.Ile394Asn)
c.878T>A (p.Ile293Asn)
c.1325T>A (p.Ile442Asn)
c.1418T>A (p.Ile473Asn)
 gnomAD v4
7g.99760908T>ACA368368611CYP3A4c.1420A>T (p.Ile474Phe)
n.762A>T
c.1327A>T (p.Ile443Phe)
c.868A>T (p.Ile290Phe)
c.1180A>T (p.Ile394Phe)
c.877A>T (p.Ile293Phe)
c.1324A>T (p.Ile442Phe)
c.1417A>T (p.Ile473Phe)
7g.99760908T>CCA368368612CYP3A4c.1420A>G (p.Ile474Val)
n.762A>G
c.1327A>G (p.Ile443Val)
c.868A>G (p.Ile290Val)
c.1180A>G (p.Ile394Val)
c.877A>G (p.Ile293Val)
c.1324A>G (p.Ile442Val)
c.1417A>G (p.Ile473Val)
 ClinVar gnomAD v4
7g.99760908T>GCA368368613CYP3A4c.1420A>C (p.Ile474Leu)
n.762A>C
c.1327A>C (p.Ile443Leu)
c.868A>C (p.Ile290Leu)
c.1180A>C (p.Ile394Leu)
c.877A>C (p.Ile293Leu)
c.1324A>C (p.Ile442Leu)
c.1417A>C (p.Ile473Leu)
7g.99760909G>ACA456686609CYP3A4c.1419C>T (p.Cys473=)
n.761C>T
c.1326C>T (p.Cys442=)
c.867C>T (p.Cys289=)
c.1179C>T (p.Cys393=)
c.876C>T (p.Cys292=)
c.1323C>T (p.Cys441=)
c.1416C>T (p.Cys472=)
 dbSNP
7g.99760909G>CCA368368614CYP3A4c.1419C>G (p.Cys473Trp)
n.761C>G
c.1326C>G (p.Cys442Trp)
c.867C>G (p.Cys289Trp)
c.1179C>G (p.Cys393Trp)
c.876C>G (p.Cys292Trp)
c.1323C>G (p.Cys441Trp)
c.1416C>G (p.Cys472Trp)
7g.99760909G>TCA368368615CYP3A4c.1419C>A (p.Cys473Ter)
n.761C>A
c.1326C>A (p.Cys442Ter)
c.867C>A (p.Cys289Ter)
c.1179C>A (p.Cys393Ter)
c.876C>A (p.Cys292Ter)
c.1323C>A (p.Cys441Ter)
c.1416C>A (p.Cys472Ter)
7g.99760910C>ACA368368618CYP3A4c.1418G>T (p.Cys473Phe)
n.760G>T
c.1325G>T (p.Cys442Phe)
c.866G>T (p.Cys289Phe)
c.1178G>T (p.Cys393Phe)
c.875G>T (p.Cys292Phe)
c.1322G>T (p.Cys441Phe)
c.1415G>T (p.Cys472Phe)
7g.99760910C>GCA368368616CYP3A4c.1418G>C (p.Cys473Ser)
n.760G>C
c.1325G>C (p.Cys442Ser)
c.866G>C (p.Cys289Ser)
c.1178G>C (p.Cys393Ser)
c.875G>C (p.Cys292Ser)
c.1322G>C (p.Cys441Ser)
c.1415G>C (p.Cys472Ser)
7g.99760910C>TCA368368617CYP3A4c.1418G>A (p.Cys473Tyr)
n.760G>A
c.1325G>A (p.Cys442Tyr)
c.866G>A (p.Cys289Tyr)
c.1178G>A (p.Cys393Tyr)
c.875G>A (p.Cys292Tyr)
c.1322G>A (p.Cys441Tyr)
c.1415G>A (p.Cys472Tyr)
7g.99760911A>CCA368368619CYP3A4c.1417T>G (p.Cys473Gly)
n.759T>G
c.1324T>G (p.Cys442Gly)
c.865T>G (p.Cys289Gly)
c.1177T>G (p.Cys393Gly)
c.874T>G (p.Cys292Gly)
c.1321T>G (p.Cys441Gly)
c.1414T>G (p.Cys472Gly)
7g.99760911A>GCA368368620CYP3A4c.1417T>C (p.Cys473Arg)
n.759T>C
c.1324T>C (p.Cys442Arg)
c.865T>C (p.Cys289Arg)
c.1177T>C (p.Cys393Arg)
c.874T>C (p.Cys292Arg)
c.1321T>C (p.Cys441Arg)
c.1414T>C (p.Cys472Arg)
7g.99760911A>TCA368368621CYP3A4c.1417T>A (p.Cys473Ser)
n.759T>A
c.1324T>A (p.Cys442Ser)
c.865T>A (p.Cys289Ser)
c.1177T>A (p.Cys393Ser)
c.874T>A (p.Cys292Ser)
c.1321T>A (p.Cys441Ser)
c.1414T>A (p.Cys472Ser)
7g.99760912G>ACA456686610CYP3A4c.1416C>T (p.Asn472=)
n.758C>T
c.1323C>T (p.Asn441=)
c.864C>T (p.Asn288=)
c.1176C>T (p.Asn392=)
c.873C>T (p.Asn291=)
c.1320C>T (p.Asn440=)
c.1413C>T (p.Asn471=)
 dbSNP
7g.99760912G>CCA368368622CYP3A4c.1416C>G (p.Asn472Lys)
n.758C>G
c.1323C>G (p.Asn441Lys)
c.864C>G (p.Asn288Lys)
c.1176C>G (p.Asn392Lys)
c.873C>G (p.Asn291Lys)
c.1320C>G (p.Asn440Lys)
c.1413C>G (p.Asn471Lys)
7g.99760912G>TCA368368623CYP3A4c.1416C>A (p.Asn472Lys)
n.758C>A
c.1323C>A (p.Asn441Lys)
c.864C>A (p.Asn288Lys)
c.1176C>A (p.Asn392Lys)
c.873C>A (p.Asn291Lys)
c.1320C>A (p.Asn440Lys)
c.1413C>A (p.Asn471Lys)
7g.99760913T>ACA368368624CYP3A4c.1415A>T (p.Asn472Ile)
n.757A>T
c.1322A>T (p.Asn441Ile)
c.863A>T (p.Asn288Ile)
c.1175A>T (p.Asn392Ile)
c.872A>T (p.Asn291Ile)
c.1319A>T (p.Asn440Ile)
c.1412A>T (p.Asn471Ile)
7g.99760913T>CCA368368625CYP3A4c.1415A>G (p.Asn472Ser)
n.757A>G
c.1322A>G (p.Asn441Ser)
c.863A>G (p.Asn288Ser)
c.1175A>G (p.Asn392Ser)
c.872A>G (p.Asn291Ser)
c.1319A>G (p.Asn440Ser)
c.1412A>G (p.Asn471Ser)
7g.99760913T>GCA368368626CYP3A4c.1415A>C (p.Asn472Thr)
n.757A>C
c.1322A>C (p.Asn441Thr)
c.863A>C (p.Asn288Thr)
c.1175A>C (p.Asn392Thr)
c.872A>C (p.Asn291Thr)
c.1319A>C (p.Asn440Thr)
c.1412A>C (p.Asn471Thr)
7g.99760914T>ACA368368627CYP3A4c.1414A>T (p.Asn472Tyr)
n.756A>T
c.1321A>T (p.Asn441Tyr)
c.862A>T (p.Asn288Tyr)
c.1174A>T (p.Asn392Tyr)
c.871A>T (p.Asn291Tyr)
c.1318A>T (p.Asn440Tyr)
c.1411A>T (p.Asn471Tyr)
7g.99760914T>CCA163151141CYP3A4c.1414A>G (p.Asn472Asp)
n.756A>G
c.1321A>G (p.Asn441Asp)
c.862A>G (p.Asn288Asp)
c.1174A>G (p.Asn392Asp)
c.871A>G (p.Asn291Asp)
c.1318A>G (p.Asn440Asp)
c.1411A>G (p.Asn471Asp)
 dbSNP gnomAD v3 gnomAD v4
7g.99760914T>GCA368368628CYP3A4c.1414A>C (p.Asn472His)
n.756A>C
c.1321A>C (p.Asn441His)
c.862A>C (p.Asn288His)
c.1174A>C (p.Asn392His)
c.871A>C (p.Asn291His)
c.1318A>C (p.Asn440His)
c.1411A>C (p.Asn471His)
7g.99760914T=CA1729176772CYP3A4c.1414A= (p.Asn472=)
n.756A=
c.1321A= (p.Asn441=)
c.862A= (p.Asn288=)
c.1174A= (p.Asn392=)
c.871A= (p.Asn291=)
c.1318A= (p.Asn440=)
c.1411A= (p.Asn471=)
7g.99760915T>ACA368368629CYP3A4c.1413A>T (p.Arg471Ser)
n.755A>T
c.1320A>T (p.Arg440Ser)
c.861A>T (p.Arg287Ser)
c.1173A>T (p.Arg391Ser)
c.870A>T (p.Arg290Ser)
c.1317A>T (p.Arg439Ser)
c.1410A>T (p.Arg470Ser)
7g.99760915T>CCA456686613CYP3A4c.1413A>G (p.Arg471=)
n.755A>G
c.1320A>G (p.Arg440=)
c.861A>G (p.Arg287=)
c.1173A>G (p.Arg391=)
c.870A>G (p.Arg290=)
c.1317A>G (p.Arg439=)
c.1410A>G (p.Arg470=)
7g.99760915T>GCA368368630CYP3A4c.1413A>C (p.Arg471Ser)
n.755A>C
c.1320A>C (p.Arg440Ser)
c.861A>C (p.Arg287Ser)
c.1173A>C (p.Arg391Ser)
c.870A>C (p.Arg290Ser)
c.1317A>C (p.Arg439Ser)
c.1410A>C (p.Arg470Ser)
7g.99760916C>ACA368368631CYP3A4c.1412G>T (p.Arg471Ile)
n.754G>T
c.1319G>T (p.Arg440Ile)
c.860G>T (p.Arg287Ile)
c.1172G>T (p.Arg391Ile)
c.869G>T (p.Arg290Ile)
c.1316G>T (p.Arg439Ile)
c.1409G>T (p.Arg470Ile)
7g.99760916C>GCA368368632CYP3A4c.1412G>C (p.Arg471Thr)
n.754G>C
c.1319G>C (p.Arg440Thr)
c.860G>C (p.Arg287Thr)
c.1172G>C (p.Arg391Thr)
c.869G>C (p.Arg290Thr)
c.1316G>C (p.Arg439Thr)
c.1409G>C (p.Arg470Thr)
7g.99760916C>TCA368368633CYP3A4c.1412G>A (p.Arg471Lys)
n.754G>A
c.1319G>A (p.Arg440Lys)
c.860G>A (p.Arg287Lys)
c.1172G>A (p.Arg391Lys)
c.869G>A (p.Arg290Lys)
c.1316G>A (p.Arg439Lys)
c.1409G>A (p.Arg470Lys)
 COSMIC
7g.99760917T>ACA368368634CYP3A4c.1411A>T (p.Arg471Ter)
n.753A>T
c.1318A>T (p.Arg440Ter)
c.859A>T (p.Arg287Ter)
c.1171A>T (p.Arg391Ter)
c.868A>T (p.Arg290Ter)
c.1315A>T (p.Arg439Ter)
c.1408A>T (p.Arg470Ter)
7g.99760917T>CCA368368635CYP3A4c.1411A>G (p.Arg471Gly)
n.753A>G
c.1318A>G (p.Arg440Gly)
c.859A>G (p.Arg287Gly)
c.1171A>G (p.Arg391Gly)
c.868A>G (p.Arg290Gly)
c.1315A>G (p.Arg439Gly)
c.1408A>G (p.Arg470Gly)
7g.99760917T>GCA456686615CYP3A4c.1411A>C (p.Arg471=)
n.753A>C
c.1318A>C (p.Arg440=)
c.859A>C (p.Arg287=)
c.1171A>C (p.Arg391=)
c.868A>C (p.Arg290=)
c.1315A>C (p.Arg439=)
c.1408A>C (p.Arg470=)
7g.99760918G>ACA4369499CYP3A4c.1410C>T (p.Pro470=)
n.752C>T
c.1317C>T (p.Pro439=)
c.858C>T (p.Pro286=)
c.1170C>T (p.Pro390=)
c.867C>T (p.Pro289=)
c.1314C>T (p.Pro438=)
c.1407C>T (p.Pro469=)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4 COSMIC
7g.99760918G>CCA456686616CYP3A4c.1410C>G (p.Pro470=)
n.752C>G
c.1317C>G (p.Pro439=)
c.858C>G (p.Pro286=)
c.1170C>G (p.Pro390=)
c.867C>G (p.Pro289=)
c.1314C>G (p.Pro438=)
c.1407C>G (p.Pro469=)
7g.99760918G=CA1729176773CYP3A4c.1410C= (p.Pro470=)
n.752C=
c.1317C= (p.Pro439=)
c.858C= (p.Pro286=)
c.1170C= (p.Pro390=)
c.867C= (p.Pro289=)
c.1314C= (p.Pro438=)
c.1407C= (p.Pro469=)
7g.99760918G>TCA4369500CYP3A4c.1410C>A (p.Pro470=)
n.752C>A
c.1317C>A (p.Pro439=)
c.858C>A (p.Pro286=)
c.1170C>A (p.Pro390=)
c.867C>A (p.Pro289=)
c.1314C>A (p.Pro438=)
c.1407C>A (p.Pro469=)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760919G>ACA368368636CYP3A4c.1409C>T (p.Pro470Leu)
n.751C>T
c.1316C>T (p.Pro439Leu)
c.857C>T (p.Pro286Leu)
c.1169C>T (p.Pro390Leu)
c.866C>T (p.Pro289Leu)
c.1313C>T (p.Pro438Leu)
c.1406C>T (p.Pro469Leu)
7g.99760919G>CCA368368637CYP3A4c.1409C>G (p.Pro470Arg)
n.751C>G
c.1316C>G (p.Pro439Arg)
c.857C>G (p.Pro286Arg)
c.1169C>G (p.Pro390Arg)
c.866C>G (p.Pro289Arg)
c.1313C>G (p.Pro438Arg)
c.1406C>G (p.Pro469Arg)
7g.99760919G>TCA368368638CYP3A4c.1409C>A (p.Pro470His)
n.751C>A
c.1316C>A (p.Pro439His)
c.857C>A (p.Pro286His)
c.1169C>A (p.Pro390His)
c.866C>A (p.Pro289His)
c.1313C>A (p.Pro438His)
c.1406C>A (p.Pro469His)
7g.99760920G>ACA368368639CYP3A4c.1408C>T (p.Pro470Ser)
n.750C>T
c.1315C>T (p.Pro439Ser)
c.856C>T (p.Pro286Ser)
c.1168C>T (p.Pro390Ser)
c.865C>T (p.Pro289Ser)
c.1312C>T (p.Pro438Ser)
c.1405C>T (p.Pro469Ser)
 dbSNP gnomAD v2
7g.99760920G>CCA368368640CYP3A4c.1408C>G (p.Pro470Ala)
n.750C>G
c.1315C>G (p.Pro439Ala)
c.856C>G (p.Pro286Ala)
c.1168C>G (p.Pro390Ala)
c.865C>G (p.Pro289Ala)
c.1312C>G (p.Pro438Ala)
c.1405C>G (p.Pro469Ala)
7g.99760920G=CA1729176774CYP3A4c.1408C= (p.Pro470=)
n.750C=
c.1315C= (p.Pro439=)
c.856C= (p.Pro286=)
c.1168C= (p.Pro390=)
c.865C= (p.Pro289=)
c.1312C= (p.Pro438=)
c.1405C= (p.Pro469=)
7g.99760920G>TCA368368641CYP3A4c.1408C>A (p.Pro470Thr)
n.750C>A
c.1315C>A (p.Pro439Thr)
c.856C>A (p.Pro286Thr)
c.1168C>A (p.Pro390Thr)
c.865C>A (p.Pro289Thr)
c.1312C>A (p.Pro438Thr)
c.1405C>A (p.Pro469Thr)
7g.99760921T>ACA456686620CYP3A4c.1407A>T (p.Gly469=)
n.749A>T
c.1314A>T (p.Gly438=)
c.855A>T (p.Gly285=)
c.1167A>T (p.Gly389=)
c.864A>T (p.Gly288=)
c.1311A>T (p.Gly437=)
c.1404A>T (p.Gly468=)
7g.99760921T>CCA456686621CYP3A4c.1407A>G (p.Gly469=)
n.749A>G
c.1314A>G (p.Gly438=)
c.855A>G (p.Gly285=)
c.1167A>G (p.Gly389=)
c.864A>G (p.Gly288=)
c.1311A>G (p.Gly437=)
c.1404A>G (p.Gly468=)
7g.99760921T>GCA456686622CYP3A4c.1407A>C (p.Gly469=)
n.749A>C
c.1314A>C (p.Gly438=)
c.855A>C (p.Gly285=)
c.1167A>C (p.Gly389=)
c.864A>C (p.Gly288=)
c.1311A>C (p.Gly437=)
c.1404A>C (p.Gly468=)
7g.99760922C>ACA368368644CYP3A4c.1406G>T (p.Gly469Val)
n.748G>T
c.1313G>T (p.Gly438Val)
c.854G>T (p.Gly285Val)
c.1166G>T (p.Gly389Val)
c.863G>T (p.Gly288Val)
c.1310G>T (p.Gly437Val)
c.1403G>T (p.Gly468Val)
 dbSNP gnomAD v2 gnomAD v4
7g.99760922C=CA1729176775CYP3A4c.1406G= (p.Gly469=)
n.748G=
c.1313G= (p.Gly438=)
c.854G= (p.Gly285=)
c.1166G= (p.Gly389=)
c.863G= (p.Gly288=)
c.1310G= (p.Gly437=)
c.1403G= (p.Gly468=)
7g.99760922C>GCA368368642CYP3A4c.1406G>C (p.Gly469Ala)
n.748G>C
c.1313G>C (p.Gly438Ala)
c.854G>C (p.Gly285Ala)
c.1166G>C (p.Gly389Ala)
c.863G>C (p.Gly288Ala)
c.1310G>C (p.Gly437Ala)
c.1403G>C (p.Gly468Ala)
7g.99760922C>TCA368368643CYP3A4c.1406G>A (p.Gly469Glu)
n.748G>A
c.1313G>A (p.Gly438Glu)
c.854G>A (p.Gly285Glu)
c.1166G>A (p.Gly389Glu)
c.863G>A (p.Gly288Glu)
c.1310G>A (p.Gly437Glu)
c.1403G>A (p.Gly468Glu)
7g.99760923C>ACA368368645CYP3A4c.1405G>T (p.Gly469Ter)
n.747G>T
c.1312G>T (p.Gly438Ter)
c.853G>T (p.Gly285Ter)
c.1165G>T (p.Gly389Ter)
c.862G>T (p.Gly288Ter)
c.1309G>T (p.Gly437Ter)
c.1402G>T (p.Gly468Ter)
7g.99760923C>GCA368368646CYP3A4c.1405G>C (p.Gly469Arg)
n.747G>C
c.1312G>C (p.Gly438Arg)
c.853G>C (p.Gly285Arg)
c.1165G>C (p.Gly389Arg)
c.862G>C (p.Gly288Arg)
c.1309G>C (p.Gly437Arg)
c.1402G>C (p.Gly468Arg)
7g.99760923C>TCA368368647CYP3A4c.1405G>A (p.Gly469Arg)
n.747G>A
c.1312G>A (p.Gly438Arg)
c.853G>A (p.Gly285Arg)
c.1165G>A (p.Gly389Arg)
c.862G>A (p.Gly288Arg)
c.1309G>A (p.Gly437Arg)
c.1402G>A (p.Gly468Arg)
7g.99760924A=CA1729176776CYP3A4c.1404T= (p.Ser468=)
n.746T=
c.1311T= (p.Ser437=)
c.852T= (p.Ser284=)
c.1164T= (p.Ser388=)
c.861T= (p.Ser287=)
c.1308T= (p.Ser436=)
c.1401T= (p.Ser467=)
7g.99760924A>CCA368368648CYP3A4c.1404T>G (p.Ser468Arg)
n.746T>G
c.1311T>G (p.Ser437Arg)
c.852T>G (p.Ser284Arg)
c.1164T>G (p.Ser388Arg)
c.861T>G (p.Ser287Arg)
c.1308T>G (p.Ser436Arg)
c.1401T>G (p.Ser467Arg)
7g.99760924A>GCA456686626CYP3A4c.1404T>C (p.Ser468=)
n.746T>C
c.1311T>C (p.Ser437=)
c.852T>C (p.Ser284=)
c.1164T>C (p.Ser388=)
c.861T>C (p.Ser287=)
c.1308T>C (p.Ser436=)
c.1401T>C (p.Ser467=)
 dbSNP gnomAD v2 gnomAD v4
7g.99760924A>TCA368368649CYP3A4c.1404T>A (p.Ser468Arg)
n.746T>A
c.1311T>A (p.Ser437Arg)
c.852T>A (p.Ser284Arg)
c.1164T>A (p.Ser388Arg)
c.861T>A (p.Ser287Arg)
c.1308T>A (p.Ser436Arg)
c.1401T>A (p.Ser467Arg)
7g.99760925C>ACA368368650CYP3A4c.1403G>T (p.Ser468Ile)
n.745G>T
c.1310G>T (p.Ser437Ile)
c.851G>T (p.Ser284Ile)
c.1163G>T (p.Ser388Ile)
c.860G>T (p.Ser287Ile)
c.1307G>T (p.Ser436Ile)
c.1400G>T (p.Ser467Ile)
7g.99760925C=CA1729176777CYP3A4c.1403G= (p.Ser468=)
n.745G=
c.1310G= (p.Ser437=)
c.851G= (p.Ser284=)
c.1163G= (p.Ser388=)
c.860G= (p.Ser287=)
c.1307G= (p.Ser436=)
c.1400G= (p.Ser467=)
7g.99760925C>GCA368368651CYP3A4c.1403G>C (p.Ser468Thr)
n.745G>C
c.1310G>C (p.Ser437Thr)
c.851G>C (p.Ser284Thr)
c.1163G>C (p.Ser388Thr)
c.860G>C (p.Ser287Thr)
c.1307G>C (p.Ser436Thr)
c.1400G>C (p.Ser467Thr)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
7g.99760925C>TCA368368652CYP3A4c.1403G>A (p.Ser468Asn)
n.745G>A
c.1310G>A (p.Ser437Asn)
c.851G>A (p.Ser284Asn)
c.1163G>A (p.Ser388Asn)
c.860G>A (p.Ser287Asn)
c.1307G>A (p.Ser436Asn)
c.1400G>A (p.Ser467Asn)
7g.99760926T>ACA368368653CYP3A4c.1402A>T (p.Ser468Cys)
n.744A>T
c.1309A>T (p.Ser437Cys)
c.850A>T (p.Ser284Cys)
c.1162A>T (p.Ser388Cys)
c.859A>T (p.Ser287Cys)
c.1306A>T (p.Ser436Cys)
c.1399A>T (p.Ser467Cys)
7g.99760926T>CCA368368654CYP3A4c.1402A>G (p.Ser468Gly)
n.744A>G
c.1309A>G (p.Ser437Gly)
c.850A>G (p.Ser284Gly)
c.1162A>G (p.Ser388Gly)
c.859A>G (p.Ser287Gly)
c.1306A>G (p.Ser436Gly)
c.1399A>G (p.Ser467Gly)
7g.99760926T>GCA368368655CYP3A4c.1402A>C (p.Ser468Arg)
n.744A>C
c.1309A>C (p.Ser437Arg)
c.850A>C (p.Ser284Arg)
c.1162A>C (p.Ser388Arg)
c.859A>C (p.Ser287Arg)
c.1306A>C (p.Ser436Arg)
c.1399A>C (p.Ser467Arg)
7g.99760927T>ACA456686627CYP3A4c.1401A>T (p.Gly467=)
n.743A>T
c.1308A>T (p.Gly436=)
c.849A>T (p.Gly283=)
c.1161A>T (p.Gly387=)
c.858A>T (p.Gly286=)
c.1305A>T (p.Gly435=)
c.1398A>T (p.Gly466=)
7g.99760927T>CCA456686628CYP3A4c.1401A>G (p.Gly467=)
n.743A>G
c.1308A>G (p.Gly436=)
c.849A>G (p.Gly283=)
c.1161A>G (p.Gly387=)
c.858A>G (p.Gly286=)
c.1305A>G (p.Gly435=)
c.1398A>G (p.Gly466=)
 gnomAD v4
7g.99760927T>GCA456686630CYP3A4c.1401A>C (p.Gly467=)
n.743A>C
c.1308A>C (p.Gly436=)
c.849A>C (p.Gly283=)
c.1161A>C (p.Gly387=)
c.858A>C (p.Gly286=)
c.1305A>C (p.Gly435=)
c.1398A>C (p.Gly466=)
7g.99760928C>ACA368368658CYP3A4c.1400G>T (p.Gly467Val)
n.742G>T
c.1307G>T (p.Gly436Val)
c.848G>T (p.Gly283Val)
c.1160G>T (p.Gly387Val)
c.857G>T (p.Gly286Val)
c.1304G>T (p.Gly435Val)
c.1397G>T (p.Gly466Val)
7g.99760928C>GCA368368657CYP3A4c.1400G>C (p.Gly467Ala)
n.742G>C
c.1307G>C (p.Gly436Ala)
c.848G>C (p.Gly283Ala)
c.1160G>C (p.Gly387Ala)
c.857G>C (p.Gly286Ala)
c.1304G>C (p.Gly435Ala)
c.1397G>C (p.Gly466Ala)
7g.99760928C>TCA368368656CYP3A4c.1400G>A (p.Gly467Glu)
n.742G>A
c.1307G>A (p.Gly436Glu)
c.848G>A (p.Gly283Glu)
c.1160G>A (p.Gly387Glu)
c.857G>A (p.Gly286Glu)
c.1304G>A (p.Gly435Glu)
c.1397G>A (p.Gly466Glu)
 dbSNP
7g.99760929C>ACA368368659CYP3A4c.1399G>T (p.Gly467Ter)
n.741G>T
c.1306G>T (p.Gly436Ter)
c.847G>T (p.Gly283Ter)
c.1159G>T (p.Gly387Ter)
c.856G>T (p.Gly286Ter)
c.1303G>T (p.Gly435Ter)
c.1396G>T (p.Gly466Ter)
7g.99760929C=CA1729176778CYP3A4c.1399G= (p.Gly467=)
n.741G=
c.1306G= (p.Gly436=)
c.847G= (p.Gly283=)
c.1159G= (p.Gly387=)
c.856G= (p.Gly286=)
c.1303G= (p.Gly435=)
c.1396G= (p.Gly466=)
7g.99760929C>GCA368368660CYP3A4c.1399G>C (p.Gly467Arg)
n.741G>C
c.1306G>C (p.Gly436Arg)
c.847G>C (p.Gly283Arg)
c.1159G>C (p.Gly387Arg)
c.856G>C (p.Gly286Arg)
c.1303G>C (p.Gly435Arg)
c.1396G>C (p.Gly466Arg)
7g.99760929C>TCA4369501CYP3A4c.1399G>A (p.Gly467Arg)
n.741G>A
c.1306G>A (p.Gly436Arg)
c.847G>A (p.Gly283Arg)
c.1159G>A (p.Gly387Arg)
c.856G>A (p.Gly286Arg)
c.1303G>A (p.Gly435Arg)
c.1396G>A (p.Gly466Arg)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760930A=CA1729176779CYP3A4c.1398T= (p.Phe466=)
n.740T=
c.1305T= (p.Phe435=)
c.846T= (p.Phe282=)
c.1158T= (p.Phe386=)
c.855T= (p.Phe285=)
c.1302T= (p.Phe434=)
c.1395T= (p.Phe465=)
7g.99760930A>CCA368368661CYP3A4c.1398T>G (p.Phe466Leu)
n.740T>G
c.1305T>G (p.Phe435Leu)
c.846T>G (p.Phe282Leu)
c.1158T>G (p.Phe386Leu)
c.855T>G (p.Phe285Leu)
c.1302T>G (p.Phe434Leu)
c.1395T>G (p.Phe465Leu)
7g.99760930A>GCA4369502CYP3A4c.1398T>C (p.Phe466=)
n.740T>C
c.1305T>C (p.Phe435=)
c.846T>C (p.Phe282=)
c.1158T>C (p.Phe386=)
c.855T>C (p.Phe285=)
c.1302T>C (p.Phe434=)
c.1395T>C (p.Phe465=)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760930A>TCA368368662CYP3A4c.1398T>A (p.Phe466Leu)
n.740T>A
c.1305T>A (p.Phe435Leu)
c.846T>A (p.Phe282Leu)
c.1158T>A (p.Phe386Leu)
c.855T>A (p.Phe285Leu)
c.1302T>A (p.Phe434Leu)
c.1395T>A (p.Phe465Leu)
7g.99760931A>CCA368368665CYP3A4c.1397T>G (p.Phe466Cys)
n.739T>G
c.1304T>G (p.Phe435Cys)
c.845T>G (p.Phe282Cys)
c.1157T>G (p.Phe386Cys)
c.854T>G (p.Phe285Cys)
c.1301T>G (p.Phe434Cys)
c.1394T>G (p.Phe465Cys)
7g.99760931A>GCA368368664CYP3A4c.1397T>C (p.Phe466Ser)
n.739T>C
c.1304T>C (p.Phe435Ser)
c.845T>C (p.Phe282Ser)
c.1157T>C (p.Phe386Ser)
c.854T>C (p.Phe285Ser)
c.1301T>C (p.Phe434Ser)
c.1394T>C (p.Phe465Ser)
7g.99760931A>TCA368368663CYP3A4c.1397T>A (p.Phe466Tyr)
n.739T>A
c.1304T>A (p.Phe435Tyr)
c.845T>A (p.Phe282Tyr)
c.1157T>A (p.Phe386Tyr)
c.854T>A (p.Phe285Tyr)
c.1301T>A (p.Phe434Tyr)
c.1394T>A (p.Phe465Tyr)
7g.99760932A>CCA368368666CYP3A4c.1396T>G (p.Phe466Val)
n.738T>G
c.1303T>G (p.Phe435Val)
c.844T>G (p.Phe282Val)
c.1156T>G (p.Phe386Val)
c.853T>G (p.Phe285Val)
c.1300T>G (p.Phe434Val)
c.1393T>G (p.Phe465Val)
7g.99760932A>GCA368368667CYP3A4c.1396T>C (p.Phe466Leu)
n.738T>C
c.1303T>C (p.Phe435Leu)
c.844T>C (p.Phe282Leu)
c.1156T>C (p.Phe386Leu)
c.853T>C (p.Phe285Leu)
c.1300T>C (p.Phe434Leu)
c.1393T>C (p.Phe465Leu)
7g.99760932A>TCA368368668CYP3A4c.1396T>A (p.Phe466Ile)
n.738T>A
c.1303T>A (p.Phe435Ile)
c.844T>A (p.Phe282Ile)
c.1156T>A (p.Phe386Ile)
c.853T>A (p.Phe285Ile)
c.1300T>A (p.Phe434Ile)
c.1393T>A (p.Phe465Ile)
7g.99760933G>ACA456686636CYP3A4c.1395C>T (p.Pro465=)
n.737C>T
c.1302C>T (p.Pro434=)
c.843C>T (p.Pro281=)
c.1155C>T (p.Pro385=)
c.852C>T (p.Pro284=)
c.1299C>T (p.Pro433=)
c.1392C>T (p.Pro464=)
 gnomAD v4
7g.99760933G>CCA456686637CYP3A4c.1395C>G (p.Pro465=)
n.737C>G
c.1302C>G (p.Pro434=)
c.843C>G (p.Pro281=)
c.1155C>G (p.Pro385=)
c.852C>G (p.Pro284=)
c.1299C>G (p.Pro433=)
c.1392C>G (p.Pro464=)
7g.99760933G>TCA456686638CYP3A4c.1395C>A (p.Pro465=)
n.737C>A
c.1302C>A (p.Pro434=)
c.843C>A (p.Pro281=)
c.1155C>A (p.Pro385=)
c.852C>A (p.Pro284=)
c.1299C>A (p.Pro433=)
c.1392C>A (p.Pro464=)
7g.99760934G>ACA368368669CYP3A4c.1394C>T (p.Pro465Leu)
n.736C>T
c.1301C>T (p.Pro434Leu)
c.842C>T (p.Pro281Leu)
c.1154C>T (p.Pro385Leu)
c.851C>T (p.Pro284Leu)
c.1298C>T (p.Pro433Leu)
c.1391C>T (p.Pro464Leu)
7g.99760934G>CCA368368670CYP3A4c.1394C>G (p.Pro465Arg)
n.736C>G
c.1301C>G (p.Pro434Arg)
c.842C>G (p.Pro281Arg)
c.1154C>G (p.Pro385Arg)
c.851C>G (p.Pro284Arg)
c.1298C>G (p.Pro433Arg)
c.1391C>G (p.Pro464Arg)
7g.99760934G>TCA368368671CYP3A4c.1394C>A (p.Pro465His)
n.736C>A
c.1301C>A (p.Pro434His)
c.842C>A (p.Pro281His)
c.1154C>A (p.Pro385His)
c.851C>A (p.Pro284His)
c.1298C>A (p.Pro433His)
c.1391C>A (p.Pro464His)
7g.99760935G>ACA368368672CYP3A4c.1393C>T (p.Pro465Ser)
n.735C>T
c.1300C>T (p.Pro434Ser)
c.841C>T (p.Pro281Ser)
c.1153C>T (p.Pro385Ser)
c.850C>T (p.Pro284Ser)
c.1297C>T (p.Pro433Ser)
c.1390C>T (p.Pro464Ser)
 gnomAD v4
7g.99760935G>CCA368368674CYP3A4c.1393C>G (p.Pro465Ala)
n.735C>G
c.1300C>G (p.Pro434Ala)
c.841C>G (p.Pro281Ala)
c.1153C>G (p.Pro385Ala)
c.850C>G (p.Pro284Ala)
c.1297C>G (p.Pro433Ala)
c.1390C>G (p.Pro464Ala)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
7g.99760935G=CA1729176780CYP3A4c.1393C= (p.Pro465=)
n.735C=
c.1300C= (p.Pro434=)
c.841C= (p.Pro281=)
c.1153C= (p.Pro385=)
c.850C= (p.Pro284=)
c.1297C= (p.Pro433=)
c.1390C= (p.Pro464=)
7g.99760935G>TCA368368673CYP3A4c.1393C>A (p.Pro465Thr)
n.735C>A
c.1300C>A (p.Pro434Thr)
c.841C>A (p.Pro281Thr)
c.1153C>A (p.Pro385Thr)
c.850C>A (p.Pro284Thr)
c.1297C>A (p.Pro433Thr)
c.1390C>A (p.Pro464Thr)
7g.99760936T>ACA456686641CYP3A4c.1392A>T (p.Thr464=)
n.734A>T
c.1299A>T (p.Thr433=)
c.840A>T (p.Thr280=)
c.1152A>T (p.Thr384=)
c.849A>T (p.Thr283=)
c.1296A>T (p.Thr432=)
c.1389A>T (p.Thr463=)
7g.99760936T>CCA163151148CYP3A4c.1392A>G (p.Thr464=)
n.734A>G
c.1299A>G (p.Thr433=)
c.840A>G (p.Thr280=)
c.1152A>G (p.Thr384=)
c.849A>G (p.Thr283=)
c.1296A>G (p.Thr432=)
c.1389A>G (p.Thr463=)
 dbSNP
7g.99760936T>GCA456686640CYP3A4c.1392A>C (p.Thr464=)
n.734A>C
c.1299A>C (p.Thr433=)
c.840A>C (p.Thr280=)
c.1152A>C (p.Thr384=)
c.849A>C (p.Thr283=)
c.1296A>C (p.Thr432=)
c.1389A>C (p.Thr463=)
7g.99760936T=CA1729176781CYP3A4c.1392A= (p.Thr464=)
n.734A=
c.1299A= (p.Thr433=)
c.840A= (p.Thr280=)
c.1152A= (p.Thr384=)
c.849A= (p.Thr283=)
c.1296A= (p.Thr432=)
c.1389A= (p.Thr463=)
7g.99760937G>ACA4369503CYP3A4c.1391C>T (p.Thr464Ile)
n.733C>T
c.1298C>T (p.Thr433Ile)
c.839C>T (p.Thr280Ile)
c.1151C>T (p.Thr384Ile)
c.848C>T (p.Thr283Ile)
c.1295C>T (p.Thr432Ile)
c.1388C>T (p.Thr463Ile)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760937G>CCA368368675CYP3A4c.1391C>G (p.Thr464Arg)
n.733C>G
c.1298C>G (p.Thr433Arg)
c.839C>G (p.Thr280Arg)
c.1151C>G (p.Thr384Arg)
c.848C>G (p.Thr283Arg)
c.1295C>G (p.Thr432Arg)
c.1388C>G (p.Thr463Arg)
7g.99760937G=CA1729176782CYP3A4c.1391C= (p.Thr464=)
n.733C=
c.1298C= (p.Thr433=)
c.839C= (p.Thr280=)
c.1151C= (p.Thr384=)
c.848C= (p.Thr283=)
c.1295C= (p.Thr432=)
c.1388C= (p.Thr463=)
7g.99760937G>TCA368368676CYP3A4c.1391C>A (p.Thr464Lys)
n.733C>A
c.1298C>A (p.Thr433Lys)
c.839C>A (p.Thr280Lys)
c.1151C>A (p.Thr384Lys)
c.848C>A (p.Thr283Lys)
c.1295C>A (p.Thr432Lys)
c.1388C>A (p.Thr463Lys)
7g.99760938T>ACA368368677CYP3A4c.1390A>T (p.Thr464Ser)
n.732A>T
c.1297A>T (p.Thr433Ser)
c.838A>T (p.Thr280Ser)
c.1150A>T (p.Thr384Ser)
c.847A>T (p.Thr283Ser)
c.1294A>T (p.Thr432Ser)
c.1387A>T (p.Thr463Ser)
7g.99760938T>CCA368368678CYP3A4c.1390A>G (p.Thr464Ala)
n.732A>G
c.1297A>G (p.Thr433Ala)
c.838A>G (p.Thr280Ala)
c.1150A>G (p.Thr384Ala)
c.847A>G (p.Thr283Ala)
c.1294A>G (p.Thr432Ala)
c.1387A>G (p.Thr463Ala)
 dbSNP gnomAD v2 gnomAD v4
7g.99760938T>GCA368368679CYP3A4c.1390A>C (p.Thr464Pro)
n.732A>C
c.1297A>C (p.Thr433Pro)
c.838A>C (p.Thr280Pro)
c.1150A>C (p.Thr384Pro)
c.847A>C (p.Thr283Pro)
c.1294A>C (p.Thr432Pro)
c.1387A>C (p.Thr463Pro)
7g.99760938T=CA1729176783CYP3A4c.1390A= (p.Thr464=)
n.732A=
c.1297A= (p.Thr433=)
c.838A= (p.Thr280=)
c.1150A= (p.Thr384=)
c.847A= (p.Thr283=)
c.1294A= (p.Thr432=)
c.1387A= (p.Thr463=)
7g.99760939G>ACA456686643CYP3A4c.1389C>T (p.Tyr463=)
n.731C>T
c.1296C>T (p.Tyr432=)
c.837C>T (p.Tyr279=)
c.1149C>T (p.Tyr383=)
c.846C>T (p.Tyr282=)
c.1293C>T (p.Tyr431=)
c.1386C>T (p.Tyr462=)
 gnomAD v4
7g.99760939G>CCA368368680CYP3A4c.1389C>G (p.Tyr463Ter)
n.731C>G
c.1296C>G (p.Tyr432Ter)
c.837C>G (p.Tyr279Ter)
c.1149C>G (p.Tyr383Ter)
c.846C>G (p.Tyr282Ter)
c.1293C>G (p.Tyr431Ter)
c.1386C>G (p.Tyr462Ter)
7g.99760939G>TCA368368681CYP3A4c.1389C>A (p.Tyr463Ter)
n.731C>A
c.1296C>A (p.Tyr432Ter)
c.837C>A (p.Tyr279Ter)
c.1149C>A (p.Tyr383Ter)
c.846C>A (p.Tyr282Ter)
c.1293C>A (p.Tyr431Ter)
c.1386C>A (p.Tyr462Ter)
7g.99760939dupCA2683985399CYP3A4c.1389dup (p.Thr464HisfsTer?)
n.731dup
c.1296dup (p.Thr433HisfsTer?)
c.837dup (p.Thr280HisfsTer?)
c.1149dup (p.Thr384HisfsTer?)
c.846dup (p.Thr283HisfsTer?)
c.1293dup (p.Thr432HisfsTer?)
c.1386dup (p.Thr463HisfsTer?)
 gnomAD v4
7g.99760940T>ACA368368682CYP3A4c.1388A>T (p.Tyr463Phe)
n.730A>T
c.1295A>T (p.Tyr432Phe)
c.836A>T (p.Tyr279Phe)
c.1148A>T (p.Tyr383Phe)
c.845A>T (p.Tyr282Phe)
c.1292A>T (p.Tyr431Phe)
c.1385A>T (p.Tyr462Phe)
 dbSNP gnomAD v2
7g.99760940T>CCA368368683CYP3A4c.1388A>G (p.Tyr463Cys)
n.730A>G
c.1295A>G (p.Tyr432Cys)
c.836A>G (p.Tyr279Cys)
c.1148A>G (p.Tyr383Cys)
c.845A>G (p.Tyr282Cys)
c.1292A>G (p.Tyr431Cys)
c.1385A>G (p.Tyr462Cys)
7g.99760940T>GCA368368684CYP3A4c.1388A>C (p.Tyr463Ser)
n.730A>C
c.1295A>C (p.Tyr432Ser)
c.836A>C (p.Tyr279Ser)
c.1148A>C (p.Tyr383Ser)
c.845A>C (p.Tyr282Ser)
c.1292A>C (p.Tyr431Ser)
c.1385A>C (p.Tyr462Ser)
7g.99760940T=CA1729176784CYP3A4c.1388A= (p.Tyr463=)
n.730A=
c.1295A= (p.Tyr432=)
c.836A= (p.Tyr279=)
c.1148A= (p.Tyr383=)
c.845A= (p.Tyr282=)
c.1292A= (p.Tyr431=)
c.1385A= (p.Tyr462=)
7g.99760941A>CCA368368685CYP3A4c.1387T>G (p.Tyr463Asp)
n.729T>G
c.1294T>G (p.Tyr432Asp)
c.835T>G (p.Tyr279Asp)
c.1147T>G (p.Tyr383Asp)
c.844T>G (p.Tyr282Asp)
c.1291T>G (p.Tyr431Asp)
c.1384T>G (p.Tyr462Asp)
7g.99760941A>GCA368368687CYP3A4c.1387T>C (p.Tyr463His)
n.729T>C
c.1294T>C (p.Tyr432His)
c.835T>C (p.Tyr279His)
c.1147T>C (p.Tyr383His)
c.844T>C (p.Tyr282His)
c.1291T>C (p.Tyr431His)
c.1384T>C (p.Tyr462His)
 gnomAD v4
7g.99760941A>TCA368368686CYP3A4c.1387T>A (p.Tyr463Asn)
n.729T>A
c.1294T>A (p.Tyr432Asn)
c.835T>A (p.Tyr279Asn)
c.1147T>A (p.Tyr383Asn)
c.844T>A (p.Tyr282Asn)
c.1291T>A (p.Tyr431Asn)
c.1384T>A (p.Tyr462Asn)
7g.99760942T>ACA456686647CYP3A4c.1386A>T (p.Ile462=)
n.728A>T
c.1293A>T (p.Ile431=)
c.834A>T (p.Ile278=)
c.1146A>T (p.Ile382=)
c.843A>T (p.Ile281=)
c.1290A>T (p.Ile430=)
c.1383A>T (p.Ile461=)
7g.99760942T>CCA368368688CYP3A4c.1386A>G (p.Ile462Met)
n.728A>G
c.1293A>G (p.Ile431Met)
c.834A>G (p.Ile278Met)
c.1146A>G (p.Ile382Met)
c.843A>G (p.Ile281Met)
c.1290A>G (p.Ile430Met)
c.1383A>G (p.Ile461Met)
7g.99760942T>GCA456686648CYP3A4c.1386A>C (p.Ile462=)
n.728A>C
c.1293A>C (p.Ile431=)
c.834A>C (p.Ile278=)
c.1146A>C (p.Ile382=)
c.843A>C (p.Ile281=)
c.1290A>C (p.Ile430=)
c.1383A>C (p.Ile461=)
7g.99760943A=CA1729176785CYP3A4c.1385T= (p.Ile462=)
n.727T=
c.1292T= (p.Ile431=)
c.833T= (p.Ile278=)
c.1145T= (p.Ile382=)
c.842T= (p.Ile281=)
c.1289T= (p.Ile430=)
c.1382T= (p.Ile461=)
7g.99760943A>CCA368368689CYP3A4c.1385T>G (p.Ile462Arg)
n.727T>G
c.1292T>G (p.Ile431Arg)
c.833T>G (p.Ile278Arg)
c.1145T>G (p.Ile382Arg)
c.842T>G (p.Ile281Arg)
c.1289T>G (p.Ile430Arg)
c.1382T>G (p.Ile461Arg)
 gnomAD v4
7g.99760943A>GCA163151158CYP3A4c.1385T>C (p.Ile462Thr)
n.727T>C
c.1292T>C (p.Ile431Thr)
c.833T>C (p.Ile278Thr)
c.1145T>C (p.Ile382Thr)
c.842T>C (p.Ile281Thr)
c.1289T>C (p.Ile430Thr)
c.1382T>C (p.Ile461Thr)
 dbSNP
7g.99760943A>TCA368368690CYP3A4c.1385T>A (p.Ile462Lys)
n.727T>A
c.1292T>A (p.Ile431Lys)
c.833T>A (p.Ile278Lys)
c.1145T>A (p.Ile382Lys)
c.842T>A (p.Ile281Lys)
c.1289T>A (p.Ile430Lys)
c.1382T>A (p.Ile461Lys)
7g.99760944T>ACA368368691CYP3A4c.1384A>T (p.Ile462Leu)
n.726A>T
c.1291A>T (p.Ile431Leu)
c.832A>T (p.Ile278Leu)
c.1144A>T (p.Ile382Leu)
c.841A>T (p.Ile281Leu)
c.1288A>T (p.Ile430Leu)
c.1381A>T (p.Ile461Leu)
7g.99760944T>CCA368368692CYP3A4c.1384A>G (p.Ile462Val)
n.726A>G
c.1291A>G (p.Ile431Val)
c.832A>G (p.Ile278Val)
c.1144A>G (p.Ile382Val)
c.841A>G (p.Ile281Val)
c.1288A>G (p.Ile430Val)
c.1381A>G (p.Ile461Val)
 gnomAD v4
7g.99760944T>GCA368368693CYP3A4c.1384A>C (p.Ile462Leu)
n.726A>C
c.1291A>C (p.Ile431Leu)
c.832A>C (p.Ile278Leu)
c.1144A>C (p.Ile382Leu)
c.841A>C (p.Ile281Leu)
c.1288A>C (p.Ile430Leu)
c.1381A>C (p.Ile461Leu)
7g.99760945G>ACA456686650CYP3A4c.1383C>T (p.Tyr461=)
n.725C>T
c.1290C>T (p.Tyr430=)
c.831C>T (p.Tyr277=)
c.1143C>T (p.Tyr381=)
c.840C>T (p.Tyr280=)
c.1287C>T (p.Tyr429=)
c.1380C>T (p.Tyr460=)
7g.99760945G>CCA368368694CYP3A4c.1383C>G (p.Tyr461Ter)
n.725C>G
c.1290C>G (p.Tyr430Ter)
c.831C>G (p.Tyr277Ter)
c.1143C>G (p.Tyr381Ter)
c.840C>G (p.Tyr280Ter)
c.1287C>G (p.Tyr429Ter)
c.1380C>G (p.Tyr460Ter)
7g.99760945G>TCA368368695CYP3A4c.1383C>A (p.Tyr461Ter)
n.725C>A
c.1290C>A (p.Tyr430Ter)
c.831C>A (p.Tyr277Ter)
c.1143C>A (p.Tyr381Ter)
c.840C>A (p.Tyr280Ter)
c.1287C>A (p.Tyr429Ter)
c.1380C>A (p.Tyr460Ter)
 COSMIC
7g.99760946T>ACA368368696CYP3A4c.1382A>T (p.Tyr461Phe)
n.724A>T
c.1289A>T (p.Tyr430Phe)
c.830A>T (p.Tyr277Phe)
c.1142A>T (p.Tyr381Phe)
c.839A>T (p.Tyr280Phe)
c.1286A>T (p.Tyr429Phe)
c.1379A>T (p.Tyr460Phe)
7g.99760946T>CCA368368697CYP3A4c.1382A>G (p.Tyr461Cys)
n.724A>G
c.1289A>G (p.Tyr430Cys)
c.830A>G (p.Tyr277Cys)
c.1142A>G (p.Tyr381Cys)
c.839A>G (p.Tyr280Cys)
c.1286A>G (p.Tyr429Cys)
c.1379A>G (p.Tyr460Cys)
7g.99760946T>GCA368368698CYP3A4c.1382A>C (p.Tyr461Ser)
n.724A>C
c.1289A>C (p.Tyr430Ser)
c.830A>C (p.Tyr277Ser)
c.1142A>C (p.Tyr381Ser)
c.839A>C (p.Tyr280Ser)
c.1286A>C (p.Tyr429Ser)
c.1379A>C (p.Tyr460Ser)
7g.99760947A>CCA368368701CYP3A4c.1381T>G (p.Tyr461Asp)
n.723T>G
c.1288T>G (p.Tyr430Asp)
c.829T>G (p.Tyr277Asp)
c.1141T>G (p.Tyr381Asp)
c.838T>G (p.Tyr280Asp)
c.1285T>G (p.Tyr429Asp)
c.1378T>G (p.Tyr460Asp)
7g.99760947A>GCA368368699CYP3A4c.1381T>C (p.Tyr461His)
n.723T>C
c.1288T>C (p.Tyr430His)
c.829T>C (p.Tyr277His)
c.1141T>C (p.Tyr381His)
c.838T>C (p.Tyr280His)
c.1285T>C (p.Tyr429His)
c.1378T>C (p.Tyr460His)
 gnomAD v4
7g.99760947A>TCA368368700CYP3A4c.1381T>A (p.Tyr461Asn)
n.723T>A
c.1288T>A (p.Tyr430Asn)
c.829T>A (p.Tyr277Asn)
c.1141T>A (p.Tyr381Asn)
c.838T>A (p.Tyr280Asn)
c.1285T>A (p.Tyr429Asn)
c.1378T>A (p.Tyr460Asn)
7g.99760948A=CA1729176786CYP3A4c.1380T= (p.Pro460=)
n.722T=
c.1287T= (p.Pro429=)
c.828T= (p.Pro276=)
c.1140T= (p.Pro380=)
c.837T= (p.Pro279=)
c.1284T= (p.Pro428=)
c.1377T= (p.Pro459=)
7g.99760948A>CCA456686651CYP3A4c.1380T>G (p.Pro460=)
n.722T>G
c.1287T>G (p.Pro429=)
c.828T>G (p.Pro276=)
c.1140T>G (p.Pro380=)
c.837T>G (p.Pro279=)
c.1284T>G (p.Pro428=)
c.1377T>G (p.Pro459=)
7g.99760948A>GCA4369504CYP3A4c.1380T>C (p.Pro460=)
n.722T>C
c.1287T>C (p.Pro429=)
c.828T>C (p.Pro276=)
c.1140T>C (p.Pro380=)
c.837T>C (p.Pro279=)
c.1284T>C (p.Pro428=)
c.1377T>C (p.Pro459=)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760948A>TCA456686652CYP3A4c.1380T>A (p.Pro460=)
n.722T>A
c.1287T>A (p.Pro429=)
c.828T>A (p.Pro276=)
c.1140T>A (p.Pro380=)
c.837T>A (p.Pro279=)
c.1284T>A (p.Pro428=)
c.1377T>A (p.Pro459=)
7g.99760949G>ACA163151166CYP3A4c.1379C>T (p.Pro460Leu)
n.721C>T
c.1286C>T (p.Pro429Leu)
c.827C>T (p.Pro276Leu)
c.1139C>T (p.Pro380Leu)
c.836C>T (p.Pro279Leu)
c.1283C>T (p.Pro428Leu)
c.1376C>T (p.Pro459Leu)
 dbSNP gnomAD v2 gnomAD v4
7g.99760949G>CCA4369505CYP3A4c.1379C>G (p.Pro460Arg)
n.721C>G
c.1286C>G (p.Pro429Arg)
c.827C>G (p.Pro276Arg)
c.1139C>G (p.Pro380Arg)
c.836C>G (p.Pro279Arg)
c.1283C>G (p.Pro428Arg)
c.1376C>G (p.Pro459Arg)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760949G=CA1729176787CYP3A4c.1379C= (p.Pro460=)
n.721C=
c.1286C= (p.Pro429=)
c.827C= (p.Pro276=)
c.1139C= (p.Pro380=)
c.836C= (p.Pro279=)
c.1283C= (p.Pro428=)
c.1376C= (p.Pro459=)
7g.99760949G>TCA368368702CYP3A4c.1379C>A (p.Pro460His)
n.721C>A
c.1286C>A (p.Pro429His)
c.827C>A (p.Pro276His)
c.1139C>A (p.Pro380His)
c.836C>A (p.Pro279His)
c.1283C>A (p.Pro428His)
c.1376C>A (p.Pro459His)
7g.99760950G>ACA368368703CYP3A4c.1378C>T (p.Pro460Ser)
n.720C>T
c.1285C>T (p.Pro429Ser)
c.826C>T (p.Pro276Ser)
c.1138C>T (p.Pro380Ser)
c.835C>T (p.Pro279Ser)
c.1282C>T (p.Pro428Ser)
c.1375C>T (p.Pro459Ser)
 dbSNP gnomAD v2 gnomAD v4 COSMIC
7g.99760950G>CCA368368704CYP3A4c.1378C>G (p.Pro460Ala)
n.720C>G
c.1285C>G (p.Pro429Ala)
c.826C>G (p.Pro276Ala)
c.1138C>G (p.Pro380Ala)
c.835C>G (p.Pro279Ala)
c.1282C>G (p.Pro428Ala)
c.1375C>G (p.Pro459Ala)
7g.99760950G=CA1729176788CYP3A4c.1378C= (p.Pro460=)
n.720C=
c.1285C= (p.Pro429=)
c.826C= (p.Pro276=)
c.1138C= (p.Pro380=)
c.835C= (p.Pro279=)
c.1282C= (p.Pro428=)
c.1375C= (p.Pro459=)
7g.99760950G>TCA368368705CYP3A4c.1378C>A (p.Pro460Thr)
n.720C>A
c.1285C>A (p.Pro429Thr)
c.826C>A (p.Pro276Thr)
c.1138C>A (p.Pro380Thr)
c.835C>A (p.Pro279Thr)
c.1282C>A (p.Pro428Thr)
c.1375C>A (p.Pro459Thr)
7g.99760951A=CA1729176789CYP3A4c.1377T= (p.Asp459=)
n.719T=
c.1284T= (p.Asp428=)
c.825T= (p.Asp275=)
c.1137T= (p.Asp379=)
c.834T= (p.Asp278=)
c.1281T= (p.Asp427=)
c.1374T= (p.Asp458=)
7g.99760951A>CCA368368706CYP3A4c.1377T>G (p.Asp459Glu)
n.719T>G
c.1284T>G (p.Asp428Glu)
c.825T>G (p.Asp275Glu)
c.1137T>G (p.Asp379Glu)
c.834T>G (p.Asp278Glu)
c.1281T>G (p.Asp427Glu)
c.1374T>G (p.Asp458Glu)
7g.99760951A>GCA456686655CYP3A4c.1377T>C (p.Asp459=)
n.719T>C
c.1284T>C (p.Asp428=)
c.825T>C (p.Asp275=)
c.1137T>C (p.Asp379=)
c.834T>C (p.Asp278=)
c.1281T>C (p.Asp427=)
c.1374T>C (p.Asp458=)
7g.99760951A>TCA4369506CYP3A4c.1377T>A (p.Asp459Glu)
n.719T>A
c.1284T>A (p.Asp428Glu)
c.825T>A (p.Asp275Glu)
c.1137T>A (p.Asp379Glu)
c.834T>A (p.Asp278Glu)
c.1281T>A (p.Asp427Glu)
c.1374T>A (p.Asp458Glu)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760951_99760953dupCA2683985400CYP3A4c.1375_1377dup (p.Asp459_Pro460insAsp)
n.717_719dup
c.1282_1284dup (p.Asp428_Pro429insAsp)
c.823_825dup (p.Asp275_Pro276insAsp)
c.1135_1137dup (p.Asp379_Pro380insAsp)
c.832_834dup (p.Asp278_Pro279insAsp)
c.1279_1281dup (p.Asp427_Pro428insAsp)
c.1372_1374dup (p.Asp458_Pro459insAsp)
 gnomAD v4
7g.99760952T>ACA368368707CYP3A4c.1376A>T (p.Asp459Val)
n.718A>T
c.1283A>T (p.Asp428Val)
c.824A>T (p.Asp275Val)
c.1136A>T (p.Asp379Val)
c.833A>T (p.Asp278Val)
c.1280A>T (p.Asp427Val)
c.1373A>T (p.Asp458Val)
 COSMIC
7g.99760952T>CCA368368708CYP3A4c.1376A>G (p.Asp459Gly)
n.718A>G
c.1283A>G (p.Asp428Gly)
c.824A>G (p.Asp275Gly)
c.1136A>G (p.Asp379Gly)
c.833A>G (p.Asp278Gly)
c.1280A>G (p.Asp427Gly)
c.1373A>G (p.Asp458Gly)
7g.99760952T>GCA368368709CYP3A4c.1376A>C (p.Asp459Ala)
n.718A>C
c.1283A>C (p.Asp428Ala)
c.824A>C (p.Asp275Ala)
c.1136A>C (p.Asp379Ala)
c.833A>C (p.Asp278Ala)
c.1280A>C (p.Asp427Ala)
c.1373A>C (p.Asp458Ala)
7g.99760953C>ACA368368711CYP3A4c.1375G>T (p.Asp459Tyr)
n.717G>T
c.1282G>T (p.Asp428Tyr)
c.823G>T (p.Asp275Tyr)
c.1135G>T (p.Asp379Tyr)
c.832G>T (p.Asp278Tyr)
c.1279G>T (p.Asp427Tyr)
c.1372G>T (p.Asp458Tyr)
7g.99760953C=CA1729176790CYP3A4c.1375G= (p.Asp459=)
n.717G=
c.1282G= (p.Asp428=)
c.823G= (p.Asp275=)
c.1135G= (p.Asp379=)
c.832G= (p.Asp278=)
c.1279G= (p.Asp427=)
c.1372G= (p.Asp458=)
7g.99760953C>GCA4369507CYP3A4c.1375G>C (p.Asp459His)
n.717G>C
c.1282G>C (p.Asp428His)
c.823G>C (p.Asp275His)
c.1135G>C (p.Asp379His)
c.832G>C (p.Asp278His)
c.1279G>C (p.Asp427His)
c.1372G>C (p.Asp458His)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760953C>TCA368368710CYP3A4c.1375G>A (p.Asp459Asn)
n.717G>A
c.1282G>A (p.Asp428Asn)
c.823G>A (p.Asp275Asn)
c.1135G>A (p.Asp379Asn)
c.832G>A (p.Asp278Asn)
c.1279G>A (p.Asp427Asn)
c.1372G>A (p.Asp458Asn)
 dbSNP gnomAD v2 gnomAD v4
7g.99760954T>ACA456686657CYP3A4c.1374A>T (p.Ile458=)
n.716A>T
c.1281A>T (p.Ile427=)
c.822A>T (p.Ile274=)
c.1134A>T (p.Ile378=)
c.831A>T (p.Ile277=)
c.1278A>T (p.Ile426=)
c.1371A>T (p.Ile457=)
7g.99760954T>CCA368368712CYP3A4c.1374A>G (p.Ile458Met)
n.716A>G
c.1281A>G (p.Ile427Met)
c.822A>G (p.Ile274Met)
c.1134A>G (p.Ile378Met)
c.831A>G (p.Ile277Met)
c.1278A>G (p.Ile426Met)
c.1371A>G (p.Ile457Met)
7g.99760954T>GCA456686658CYP3A4c.1374A>C (p.Ile458=)
n.716A>C
c.1281A>C (p.Ile427=)
c.822A>C (p.Ile274=)
c.1134A>C (p.Ile378=)
c.831A>C (p.Ile277=)
c.1278A>C (p.Ile426=)
c.1371A>C (p.Ile457=)
7g.99760955A>CCA368368714CYP3A4c.1373T>G (p.Ile458Arg)
n.715T>G
c.1280T>G (p.Ile427Arg)
c.821T>G (p.Ile274Arg)
c.1133T>G (p.Ile378Arg)
c.830T>G (p.Ile277Arg)
c.1277T>G (p.Ile426Arg)
c.1370T>G (p.Ile457Arg)
7g.99760955A>GCA368368713CYP3A4c.1373T>C (p.Ile458Thr)
n.715T>C
c.1280T>C (p.Ile427Thr)
c.821T>C (p.Ile274Thr)
c.1133T>C (p.Ile378Thr)
c.830T>C (p.Ile277Thr)
c.1277T>C (p.Ile426Thr)
c.1370T>C (p.Ile457Thr)
 gnomAD v4
7g.99760955A>TCA368368715CYP3A4c.1373T>A (p.Ile458Lys)
n.715T>A
c.1280T>A (p.Ile427Lys)
c.821T>A (p.Ile274Lys)
c.1133T>A (p.Ile378Lys)
c.830T>A (p.Ile277Lys)
c.1277T>A (p.Ile426Lys)
c.1370T>A (p.Ile457Lys)
7g.99760956T>ACA368368716CYP3A4c.1372A>T (p.Ile458Leu)
n.714A>T
c.1279A>T (p.Ile427Leu)
c.820A>T (p.Ile274Leu)
c.1132A>T (p.Ile378Leu)
c.829A>T (p.Ile277Leu)
c.1276A>T (p.Ile426Leu)
c.1369A>T (p.Ile457Leu)
7g.99760956T>CCA4369508CYP3A4c.1372A>G (p.Ile458Val)
n.714A>G
c.1279A>G (p.Ile427Val)
c.820A>G (p.Ile274Val)
c.1132A>G (p.Ile378Val)
c.829A>G (p.Ile277Val)
c.1276A>G (p.Ile426Val)
c.1369A>G (p.Ile457Val)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760956T>GCA368368717CYP3A4c.1372A>C (p.Ile458Leu)
n.714A>C
c.1279A>C (p.Ile427Leu)
c.820A>C (p.Ile274Leu)
c.1132A>C (p.Ile378Leu)
c.829A>C (p.Ile277Leu)
c.1276A>C (p.Ile426Leu)
c.1369A>C (p.Ile457Leu)
7g.99760956T=CA1729176791CYP3A4c.1372A= (p.Ile458=)
n.714A=
c.1279A= (p.Ile427=)
c.820A= (p.Ile274=)
c.1132A= (p.Ile378=)
c.829A= (p.Ile277=)
c.1276A= (p.Ile426=)
c.1369A= (p.Ile457=)
7g.99760957G>ACA456686660CYP3A4c.1371C>T (p.Asn457=)
n.713C>T
c.1278C>T (p.Asn426=)
c.819C>T (p.Asn273=)
c.1131C>T (p.Asn377=)
c.828C>T (p.Asn276=)
c.1275C>T (p.Asn425=)
c.1368C>T (p.Asn456=)
7g.99760957G>CCA368368718CYP3A4c.1371C>G (p.Asn457Lys)
n.713C>G
c.1278C>G (p.Asn426Lys)
c.819C>G (p.Asn273Lys)
c.1131C>G (p.Asn377Lys)
c.828C>G (p.Asn276Lys)
c.1275C>G (p.Asn425Lys)
c.1368C>G (p.Asn456Lys)
7g.99760957G=CA1729176792CYP3A4c.1371C= (p.Asn457=)
n.713C=
c.1278C= (p.Asn426=)
c.819C= (p.Asn273=)
c.1131C= (p.Asn377=)
c.828C= (p.Asn276=)
c.1275C= (p.Asn425=)
c.1368C= (p.Asn456=)
7g.99760957G>TCA368368719CYP3A4c.1371C>A (p.Asn457Lys)
n.713C>A
c.1278C>A (p.Asn426Lys)
c.819C>A (p.Asn273Lys)
c.1131C>A (p.Asn377Lys)
c.828C>A (p.Asn276Lys)
c.1275C>A (p.Asn425Lys)
c.1368C>A (p.Asn456Lys)
 dbSNP
7g.99760958T>ACA368368720CYP3A4c.1370A>T (p.Asn457Ile)
n.712A>T
c.1277A>T (p.Asn426Ile)
c.818A>T (p.Asn273Ile)
c.1130A>T (p.Asn377Ile)
c.827A>T (p.Asn276Ile)
c.1274A>T (p.Asn425Ile)
c.1367A>T (p.Asn456Ile)
7g.99760958T>CCA4369509CYP3A4c.1370A>G (p.Asn457Ser)
n.712A>G
c.1277A>G (p.Asn426Ser)
c.818A>G (p.Asn273Ser)
c.1130A>G (p.Asn377Ser)
c.827A>G (p.Asn276Ser)
c.1274A>G (p.Asn425Ser)
c.1367A>G (p.Asn456Ser)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
7g.99760958T>GCA368368721CYP3A4c.1370A>C (p.Asn457Thr)
n.712A>C
c.1277A>C (p.Asn426Thr)
c.818A>C (p.Asn273Thr)
c.1130A>C (p.Asn377Thr)
c.827A>C (p.Asn276Thr)
c.1274A>C (p.Asn425Thr)
c.1367A>C (p.Asn456Thr)
7g.99760958T=CA1729176793CYP3A4c.1370A= (p.Asn457=)
n.712A=
c.1277A= (p.Asn426=)
c.818A= (p.Asn273=)
c.1130A= (p.Asn377=)
c.827A= (p.Asn276=)
c.1274A= (p.Asn425=)
c.1367A= (p.Asn456=)
7g.99760959T>ACA368368722CYP3A4c.1369A>T (p.Asn457Tyr)
n.711A>T
c.1276A>T (p.Asn426Tyr)
c.817A>T (p.Asn273Tyr)
c.1129A>T (p.Asn377Tyr)
c.826A>T (p.Asn276Tyr)
c.1273A>T (p.Asn425Tyr)
c.1366A>T (p.Asn456Tyr)
7g.99760959T>CCA368368723CYP3A4c.1369A>G (p.Asn457Asp)
n.711A>G
c.1276A>G (p.Asn426Asp)
c.817A>G (p.Asn273Asp)
c.1129A>G (p.Asn377Asp)
c.826A>G (p.Asn276Asp)
c.1273A>G (p.Asn425Asp)
c.1366A>G (p.Asn456Asp)
7g.99760959T>GCA368368724CYP3A4c.1369A>C (p.Asn457His)
n.711A>C
c.1276A>C (p.Asn426His)
c.817A>C (p.Asn273His)
c.1129A>C (p.Asn377His)
c.826A>C (p.Asn276His)
c.1273A>C (p.Asn425His)
c.1366A>C (p.Asn456His)
7g.99760960G>ACA4369510CYP3A4c.1368C>T (p.Asp456=)
n.710C>T
c.1275C>T (p.Asp425=)
c.816C>T (p.Asp272=)
c.1128C>T (p.Asp376=)
c.825C>T (p.Asp275=)
c.1272C>T (p.Asp424=)
c.1365C>T (p.Asp455=)
 dbSNP ExAC gnomAD v2 gnomAD v4
7g.99760960G>CCA368368725CYP3A4c.1368C>G (p.Asp456Glu)
n.710C>G
c.1275C>G (p.Asp425Glu)
c.816C>G (p.Asp272Glu)
c.1128C>G (p.Asp376Glu)
c.825C>G (p.Asp275Glu)
c.1272C>G (p.Asp424Glu)
c.1365C>G (p.Asp455Glu)
 dbSNP
7g.99760960G=CA1729176794CYP3A4c.1368C= (p.Asp456=)
n.710C=
c.1275C= (p.Asp425=)
c.816C= (p.Asp272=)
c.1128C= (p.Asp376=)
c.825C= (p.Asp275=)
c.1272C= (p.Asp424=)
c.1365C= (p.Asp455=)
7g.99760960G>TCA368368726CYP3A4c.1368C>A (p.Asp456Glu)
n.710C>A
c.1275C>A (p.Asp425Glu)
c.816C>A (p.Asp272Glu)
c.1128C>A (p.Asp376Glu)
c.825C>A (p.Asp275Glu)
c.1272C>A (p.Asp424Glu)
c.1365C>A (p.Asp455Glu)
 COSMIC
7g.99760961T>ACA368368727CYP3A4c.1367A>T (p.Asp456Val)
n.709A>T
c.1274A>T (p.Asp425Val)
c.815A>T (p.Asp272Val)
c.1127A>T (p.Asp376Val)
c.824A>T (p.Asp275Val)
c.1271A>T (p.Asp424Val)
c.1364A>T (p.Asp455Val)
7g.99760961T>CCA368368728CYP3A4c.1367A>G (p.Asp456Gly)
n.709A>G
c.1274A>G (p.Asp425Gly)
c.815A>G (p.Asp272Gly)
c.1127A>G (p.Asp376Gly)
c.824A>G (p.Asp275Gly)
c.1271A>G (p.Asp424Gly)
c.1364A>G (p.Asp455Gly)
7g.99760961T>GCA368368729CYP3A4c.1367A>C (p.Asp456Ala)
n.709A>C
c.1274A>C (p.Asp425Ala)
c.815A>C (p.Asp272Ala)
c.1127A>C (p.Asp376Ala)
c.824A>C (p.Asp275Ala)
c.1271A>C (p.Asp424Ala)
c.1364A>C (p.Asp455Ala)
7g.99760962C>ACA368368732CYP3A4c.1366G>T (p.Asp456Tyr)
n.708G>T
c.1273G>T (p.Asp425Tyr)
c.814G>T (p.Asp272Tyr)
c.1126G>T (p.Asp376Tyr)
c.823G>T (p.Asp275Tyr)
c.1270G>T (p.Asp424Tyr)
c.1363G>T (p.Asp455Tyr)
7g.99760962C=CA1729176795CYP3A4c.1366G= (p.Asp456=)
n.708G=
c.1273G= (p.Asp425=)
c.814G= (p.Asp272=)
c.1126G= (p.Asp376=)
c.823G= (p.Asp275=)
c.1270G= (p.Asp424=)
c.1363G= (p.Asp455=)
7g.99760962C>GCA368368730CYP3A4c.1366G>C (p.Asp456His)
n.708G>C
c.1273G>C (p.Asp425His)
c.814G>C (p.Asp272His)
c.1126G>C (p.Asp376His)
c.823G>C (p.Asp275His)
c.1270G>C (p.Asp424His)
c.1363G>C (p.Asp455His)
7g.99760962C>TCA368368731CYP3A4c.1366G>A (p.Asp456Asn)
n.708G>A
c.1273G>A (p.Asp425Asn)
c.814G>A (p.Asp272Asn)
c.1126G>A (p.Asp376Asn)
c.823G>A (p.Asp275Asn)
c.1270G>A (p.Asp424Asn)
c.1363G>A (p.Asp455Asn)
 dbSNP gnomAD v2 gnomAD v4 COSMIC
7g.99760963C>ACA368368733CYP3A4c.1365G>T (p.Lys455Asn)
n.707G>T
c.1272G>T (p.Lys424Asn)
c.813G>T (p.Lys271Asn)
c.1125G>T (p.Lys375Asn)
c.822G>T (p.Lys274Asn)
c.1269G>T (p.Lys423Asn)
c.1362G>T (p.Lys454Asn)
7g.99760963C=CA1729176796CYP3A4c.1365G= (p.Lys455=)
n.707G=
c.1272G= (p.Lys424=)
c.813G= (p.Lys271=)
c.1125G= (p.Lys375=)
c.822G= (p.Lys274=)
c.1269G= (p.Lys423=)
c.1362G= (p.Lys454=)
7g.99760963C>GCA368368734CYP3A4c.1365G>C (p.Lys455Asn)
n.707G>C
c.1272G>C (p.Lys424Asn)
c.813G>C (p.Lys271Asn)
c.1125G>C (p.Lys375Asn)
c.822G>C (p.Lys274Asn)
c.1269G>C (p.Lys423Asn)
c.1362G>C (p.Lys454Asn)
7g.99760963C>TCA456686662CYP3A4c.1365G>A (p.Lys455=)
n.707G>A
c.1272G>A (p.Lys424=)
c.813G>A (p.Lys271=)
c.1125G>A (p.Lys375=)
c.822G>A (p.Lys274=)
c.1269G>A (p.Lys423=)
c.1362G>A (p.Lys454=)
 dbSNP
7g.99760964T>ACA368368735CYP3A4c.1364A>T (p.Lys455Met)
n.706A>T
c.1271A>T (p.Lys424Met)
c.812A>T (p.Lys271Met)
c.1124A>T (p.Lys375Met)
c.821A>T (p.Lys274Met)
c.1268A>T (p.Lys423Met)
c.1361A>T (p.Lys454Met)
7g.99760964T>CCA368368736CYP3A4c.1364A>G (p.Lys455Arg)
n.706A>G
c.1271A>G (p.Lys424Arg)
c.812A>G (p.Lys271Arg)
c.1124A>G (p.Lys375Arg)
c.821A>G (p.Lys274Arg)
c.1268A>G (p.Lys423Arg)
c.1361A>G (p.Lys454Arg)
 dbSNP gnomAD v3 gnomAD v4
7g.99760964T>GCA368368737CYP3A4c.1364A>C (p.Lys455Thr)
n.706A>C
c.1271A>C (p.Lys424Thr)
c.812A>C (p.Lys271Thr)
c.1124A>C (p.Lys375Thr)
c.821A>C (p.Lys274Thr)
c.1268A>C (p.Lys423Thr)
c.1361A>C (p.Lys454Thr)
7g.99760964T=CA1729176797CYP3A4c.1364A= (p.Lys455=)
n.706A=
c.1271A= (p.Lys424=)
c.812A= (p.Lys271=)
c.1124A= (p.Lys375=)
c.821A= (p.Lys274=)
c.1268A= (p.Lys423=)
c.1361A= (p.Lys454=)
7g.99760965T>ACA368368738CYP3A4c.1363A>T (p.Lys455Ter)
n.705A>T
c.1270A>T (p.Lys424Ter)
c.811A>T (p.Lys271Ter)
c.1123A>T (p.Lys375Ter)
c.820A>T (p.Lys274Ter)
c.1267A>T (p.Lys423Ter)
c.1360A>T (p.Lys454Ter)
7g.99760965T>CCA368368739CYP3A4c.1363A>G (p.Lys455Glu)
n.705A>G
c.1270A>G (p.Lys424Glu)
c.811A>G (p.Lys271Glu)
c.1123A>G (p.Lys375Glu)
c.820A>G (p.Lys274Glu)
c.1267A>G (p.Lys423Glu)
c.1360A>G (p.Lys454Glu)
7g.99760965T>GCA368368740CYP3A4c.1363A>C (p.Lys455Gln)
n.705A>C
c.1270A>C (p.Lys424Gln)
c.811A>C (p.Lys271Gln)
c.1123A>C (p.Lys375Gln)
c.820A>C (p.Lys274Gln)
c.1267A>C (p.Lys423Gln)
c.1360A>C (p.Lys454Gln)
7g.99760966G>ACA456686665CYP3A4c.1362C>T (p.Asn454=)
n.704C>T
c.1269C>T (p.Asn423=)
c.810C>T (p.Asn270=)
c.1122C>T (p.Asn374=)
c.819C>T (p.Asn273=)
c.1266C>T (p.Asn422=)
c.1359C>T (p.Asn453=)
 gnomAD v4
7g.99760966G>CCA368368741CYP3A4c.1362C>G (p.Asn454Lys)
n.704C>G
c.1269C>G (p.Asn423Lys)
c.810C>G (p.Asn270Lys)
c.1122C>G (p.Asn374Lys)
c.819C>G (p.Asn273Lys)
c.1266C>G (p.Asn422Lys)
c.1359C>G (p.Asn453Lys)
7g.99760966G>TCA368368742CYP3A4c.1362C>A (p.Asn454Lys)
n.704C>A
c.1269C>A (p.Asn423Lys)
c.810C>A (p.Asn270Lys)
c.1122C>A (p.Asn374Lys)
c.819C>A (p.Asn273Lys)
c.1266C>A (p.Asn422Lys)
c.1359C>A (p.Asn453Lys)
7g.99760966_99760969delinsGTTCCA1729176798CYP3A4c.1359_1362delinsGAAC (p.Lys453=)
n.701_704delinsGAAC
c.1266_1269delinsGAAC (p.Lys422=)
c.807_810delinsGAAC (p.Lys269=)
c.1119_1122delinsGAAC (p.Lys373=)
c.816_819delinsGAAC (p.Lys272=)
c.1263_1266delinsGAAC (p.Lys421=)
c.1356_1359delinsGAAC (p.Lys452=)
7g.99760967T>ACA368368745CYP3A4c.1361A>T (p.Asn454Ile)
n.703A>T
c.1268A>T (p.Asn423Ile)
c.809A>T (p.Asn270Ile)
c.1121A>T (p.Asn374Ile)
c.818A>T (p.Asn273Ile)
c.1265A>T (p.Asn422Ile)
c.1358A>T (p.Asn453Ile)
7g.99760967T>CCA368368744CYP3A4c.1361A>G (p.Asn454Ser)
n.703A>G
c.1268A>G (p.Asn423Ser)
c.809A>G (p.Asn270Ser)
c.1121A>G (p.Asn374Ser)
c.818A>G (p.Asn273Ser)
c.1265A>G (p.Asn422Ser)
c.1358A>G (p.Asn453Ser)
7g.99760967T>GCA368368743CYP3A4c.1361A>C (p.Asn454Thr)
n.703A>C
c.1268A>C (p.Asn423Thr)
c.809A>C (p.Asn270Thr)
c.1121A>C (p.Asn374Thr)
c.818A>C (p.Asn273Thr)
c.1265A>C (p.Asn422Thr)
c.1358A>C (p.Asn453Thr)
7g.99760972_99760974delCA576400468CYP3A4c.1359_1361del (p.Lys453del)
n.701_703del
c.1266_1268del (p.Lys422del)
c.807_809del (p.Lys269del)
c.1119_1121del (p.Lys373del)
c.816_818del (p.Lys272del)
c.1263_1265del (p.Lys421del)
c.1356_1358del (p.Lys452del)
 dbSNP gnomAD v2 gnomAD v4 COSMIC
7g.99760968T>ACA368368746CYP3A4c.1360A>T (p.Asn454Tyr)
n.702A>T
c.1267A>T (p.Asn423Tyr)
c.808A>T (p.Asn270Tyr)
c.1120A>T (p.Asn374Tyr)
c.817A>T (p.Asn273Tyr)
c.1264A>T (p.Asn422Tyr)
c.1357A>T (p.Asn453Tyr)
7g.99760968T>CCA368368747CYP3A4c.1360A>G (p.Asn454Asp)
n.702A>G
c.1267A>G (p.Asn423Asp)
c.808A>G (p.Asn270Asp)
c.1120A>G (p.Asn374Asp)
c.817A>G (p.Asn273Asp)
c.1264A>G (p.Asn422Asp)
c.1357A>G (p.Asn453Asp)
7g.99760968T>GCA368368748CYP3A4c.1360A>C (p.Asn454His)
n.702A>C
c.1267A>C (p.Asn423His)
c.808A>C (p.Asn270His)
c.1120A>C (p.Asn374His)
c.817A>C (p.Asn273His)
c.1264A>C (p.Asn422His)
c.1357A>C (p.Asn453His)
7g.99760969C>ACA368368749CYP3A4c.1359G>T (p.Lys453Asn)
n.701G>T
c.1266G>T (p.Lys422Asn)
c.807G>T (p.Lys269Asn)
c.1119G>T (p.Lys373Asn)
c.816G>T (p.Lys272Asn)
c.1263G>T (p.Lys421Asn)
c.1356G>T (p.Lys452Asn)
7g.99760969C>GCA368368750CYP3A4c.1359G>C (p.Lys453Asn)
n.701G>C
c.1266G>C (p.Lys422Asn)
c.807G>C (p.Lys269Asn)
c.1119G>C (p.Lys373Asn)
c.816G>C (p.Lys272Asn)
c.1263G>C (p.Lys421Asn)
c.1356G>C (p.Lys452Asn)
7g.99760969C>TCA456686667CYP3A4c.1359G>A (p.Lys453=)
n.701G>A
c.1266G>A (p.Lys422=)
c.807G>A (p.Lys269=)
c.1119G>A (p.Lys373=)
c.816G>A (p.Lys272=)
c.1263G>A (p.Lys421=)
c.1356G>A (p.Lys452=)

Number of alleles fetched