Chr Mutation (hg38) CAid Gene Transcript Linkouts
15g.66481781A>CCA392936150MAP2K1c.529A>C (p.Asn177His)
c.595A>C (p.Asn199His)
c.448A>C (p.Asn150His)
c.569-5447A>C (n.569-5447A>C)
n.953A>C
c.646A>C (p.Asn216His)
c.569-3213A>C (n.569-3213A>C)
c.451A>C (p.Asn151His)
c.67A>C (p.Asn23His)
c.517A>C (p.Asn173His)
15g.66481781A>GCA392936151MAP2K1c.529A>G (p.Asn177Asp)
c.595A>G (p.Asn199Asp)
c.448A>G (p.Asn150Asp)
c.569-5447A>G (n.569-5447A>G)
n.953A>G
c.646A>G (p.Asn216Asp)
c.569-3213A>G (n.569-3213A>G)
c.451A>G (p.Asn151Asp)
c.67A>G (p.Asn23Asp)
c.517A>G (p.Asn173Asp)
15g.66481781A>TCA392936153MAP2K1c.529A>T (p.Asn177Tyr)
c.595A>T (p.Asn199Tyr)
c.448A>T (p.Asn150Tyr)
c.569-5447A>T (n.569-5447A>T)
n.953A>T
c.646A>T (p.Asn216Tyr)
c.569-3213A>T (n.569-3213A>T)
c.451A>T (p.Asn151Tyr)
c.67A>T (p.Asn23Tyr)
c.517A>T (p.Asn173Tyr)
15g.66481782A=CA2184097400MAP2K1c.530A= (p.Asn177=)
c.596A= (p.Asn199=)
c.449A= (p.Asn150=)
c.569-5446A= (n.569-5446A=)
n.954A=
c.647A= (p.Asn216=)
c.569-3212A= (n.569-3212A=)
c.452A= (p.Asn151=)
c.68A= (p.Asn23=)
c.518A= (p.Asn173=)
15g.66481782A>CCA392936156MAP2K1c.530A>C (p.Asn177Thr)
c.596A>C (p.Asn199Thr)
c.449A>C (p.Asn150Thr)
c.569-5446A>C (n.569-5446A>C)
n.954A>C
c.647A>C (p.Asn216Thr)
c.569-3212A>C (n.569-3212A>C)
c.452A>C (p.Asn151Thr)
c.68A>C (p.Asn23Thr)
c.518A>C (p.Asn173Thr)
 dbSNP
15g.66481782A>GCA392936157MAP2K1c.530A>G (p.Asn177Ser)
c.596A>G (p.Asn199Ser)
c.449A>G (p.Asn150Ser)
c.569-5446A>G (n.569-5446A>G)
n.954A>G
c.647A>G (p.Asn216Ser)
c.569-3212A>G (n.569-3212A>G)
c.452A>G (p.Asn151Ser)
c.68A>G (p.Asn23Ser)
c.518A>G (p.Asn173Ser)
 ClinVar dbSNP gnomAD v2 gnomAD v3 gnomAD v4
15g.66481782A>TCA392936160MAP2K1c.530A>T (p.Asn177Ile)
c.596A>T (p.Asn199Ile)
c.449A>T (p.Asn150Ile)
c.569-5446A>T (n.569-5446A>T)
n.954A>T
c.647A>T (p.Asn216Ile)
c.569-3212A>T (n.569-3212A>T)
c.452A>T (p.Asn151Ile)
c.68A>T (p.Asn23Ile)
c.518A>T (p.Asn173Ile)
 dbSNP
15g.66481783C>ACA392936162MAP2K1c.531C>A (p.Asn177Lys)
c.597C>A (p.Asn199Lys)
c.450C>A (p.Asn150Lys)
c.569-5445C>A (n.569-5445C>A)
n.955C>A
c.648C>A (p.Asn216Lys)
c.569-3211C>A (n.569-3211C>A)
c.453C>A (p.Asn151Lys)
c.69C>A (p.Asn23Lys)
c.519C>A (p.Asn173Lys)
15g.66481783C>GCA392936163MAP2K1c.531C>G (p.Asn177Lys)
c.597C>G (p.Asn199Lys)
c.450C>G (p.Asn150Lys)
c.569-5445C>G (n.569-5445C>G)
n.955C>G
c.648C>G (p.Asn216Lys)
c.569-3211C>G (n.569-3211C>G)
c.453C>G (p.Asn151Lys)
c.69C>G (p.Asn23Lys)
c.519C>G (p.Asn173Lys)
 dbSNP
15g.66481783C>TCA490858395MAP2K1c.531C>T (p.Asn177=)
c.597C>T (p.Asn199=)
c.450C>T (p.Asn150=)
c.569-5445C>T (n.569-5445C>T)
n.955C>T
c.648C>T (p.Asn216=)
c.569-3211C>T (n.569-3211C>T)
c.453C>T (p.Asn151=)
c.69C>T (p.Asn23=)
c.519C>T (p.Asn173=)
 dbSNP
15g.66481784T>ACA392936169MAP2K1c.532T>A (p.Ser178Thr)
c.598T>A (p.Ser200Thr)
c.451T>A (p.Ser151Thr)
c.569-5444T>A (n.569-5444T>A)
n.956T>A
c.649T>A (p.Ser217Thr)
c.569-3210T>A (n.569-3210T>A)
c.454T>A (p.Ser152Thr)
c.70T>A (p.Ser24Thr)
c.520T>A (p.Ser174Thr)
15g.66481784T>CCA392936167MAP2K1c.532T>C (p.Ser178Pro)
c.598T>C (p.Ser200Pro)
c.451T>C (p.Ser151Pro)
c.569-5444T>C (n.569-5444T>C)
n.956T>C
c.649T>C (p.Ser217Pro)
c.569-3210T>C (n.569-3210T>C)
c.454T>C (p.Ser152Pro)
c.70T>C (p.Ser24Pro)
c.520T>C (p.Ser174Pro)
 gnomAD v4
15g.66481784T>GCA392936165MAP2K1c.532T>G (p.Ser178Ala)
c.598T>G (p.Ser200Ala)
c.451T>G (p.Ser151Ala)
c.569-5444T>G (n.569-5444T>G)
n.956T>G
c.649T>G (p.Ser217Ala)
c.569-3210T>G (n.569-3210T>G)
c.454T>G (p.Ser152Ala)
c.70T>G (p.Ser24Ala)
c.520T>G (p.Ser174Ala)
15g.66481785C>ACA392936171MAP2K1c.533C>A (p.Ser178Tyr)
c.599C>A (p.Ser200Tyr)
c.452C>A (p.Ser151Tyr)
c.569-5443C>A (n.569-5443C>A)
n.957C>A
c.650C>A (p.Ser217Tyr)
c.569-3209C>A (n.569-3209C>A)
c.455C>A (p.Ser152Tyr)
c.71C>A (p.Ser24Tyr)
c.521C>A (p.Ser174Tyr)
 dbSNP COSMIC
15g.66481785C>GCA392936172MAP2K1c.533C>G (p.Ser178Cys)
c.599C>G (p.Ser200Cys)
c.452C>G (p.Ser151Cys)
c.569-5443C>G (n.569-5443C>G)
n.957C>G
c.650C>G (p.Ser217Cys)
c.569-3209C>G (n.569-3209C>G)
c.455C>G (p.Ser152Cys)
c.71C>G (p.Ser24Cys)
c.521C>G (p.Ser174Cys)
 dbSNP
15g.66481785C>TCA392936174MAP2K1c.533C>T (p.Ser178Phe)
c.599C>T (p.Ser200Phe)
c.452C>T (p.Ser151Phe)
c.569-5443C>T (n.569-5443C>T)
n.957C>T
c.650C>T (p.Ser217Phe)
c.569-3209C>T (n.569-3209C>T)
c.455C>T (p.Ser152Phe)
c.71C>T (p.Ser24Phe)
c.521C>T (p.Ser174Phe)
 dbSNP gnomAD v4
15g.66481786C>ACA490858396MAP2K1c.534C>A (p.Ser178=)
c.600C>A (p.Ser200=)
c.453C>A (p.Ser151=)
c.569-5442C>A (n.569-5442C>A)
n.958C>A
c.651C>A (p.Ser217=)
c.569-3208C>A (n.569-3208C>A)
c.456C>A (p.Ser152=)
c.72C>A (p.Ser24=)
c.522C>A (p.Ser174=)
 dbSNP
15g.66481786C>GCA490858397MAP2K1c.534C>G (p.Ser178=)
c.600C>G (p.Ser200=)
c.453C>G (p.Ser151=)
c.569-5442C>G (n.569-5442C>G)
n.958C>G
c.651C>G (p.Ser217=)
c.569-3208C>G (n.569-3208C>G)
c.456C>G (p.Ser152=)
c.72C>G (p.Ser24=)
c.522C>G (p.Ser174=)
 dbSNP
15g.66481786C>TCA490858398MAP2K1c.534C>T (p.Ser178=)
c.600C>T (p.Ser200=)
c.453C>T (p.Ser151=)
c.569-5442C>T (n.569-5442C>T)
n.958C>T
c.651C>T (p.Ser217=)
c.569-3208C>T (n.569-3208C>T)
c.456C>T (p.Ser152=)
c.72C>T (p.Ser24=)
c.522C>T (p.Ser174=)
 ClinVar dbSNP
15g.66481787C>ACA392936176MAP2K1c.535C>A (p.Arg179Ser)
c.601C>A (p.Arg201Ser)
c.454C>A (p.Arg152Ser)
c.569-5441C>A (n.569-5441C>A)
n.959C>A
c.652C>A (p.Arg218Ser)
c.569-3207C>A (n.569-3207C>A)
c.457C>A (p.Arg153Ser)
c.73C>A (p.Arg25Ser)
c.523C>A (p.Arg175Ser)
 dbSNP gnomAD v4 COSMIC
15g.66481787C=CA2184097402MAP2K1c.535C= (p.Arg179=)
c.601C= (p.Arg201=)
c.454C= (p.Arg152=)
c.569-5441C= (n.569-5441C=)
n.959C=
c.652C= (p.Arg218=)
c.569-3207C= (n.569-3207C=)
c.457C= (p.Arg153=)
c.73C= (p.Arg25=)
c.523C= (p.Arg175=)
15g.66481787C>GCA392936178MAP2K1c.535C>G (p.Arg179Gly)
c.601C>G (p.Arg201Gly)
c.454C>G (p.Arg152Gly)
c.569-5441C>G (n.569-5441C>G)
n.959C>G
c.652C>G (p.Arg218Gly)
c.569-3207C>G (n.569-3207C>G)
c.457C>G (p.Arg153Gly)
c.73C>G (p.Arg25Gly)
c.523C>G (p.Arg175Gly)
 dbSNP
15g.66481787C>TCA7623992MAP2K1c.535C>T (p.Arg179Cys)
c.601C>T (p.Arg201Cys)
c.454C>T (p.Arg152Cys)
c.569-5441C>T (n.569-5441C>T)
n.959C>T
c.652C>T (p.Arg218Cys)
c.569-3207C>T (n.569-3207C>T)
c.457C>T (p.Arg153Cys)
c.73C>T (p.Arg25Cys)
c.523C>T (p.Arg175Cys)
 dbSNP ExAC gnomAD v2 gnomAD v4 COSMIC
15g.66481788G>ACA392936181MAP2K1c.536G>A (p.Arg179His)
c.602G>A (p.Arg201His)
c.455G>A (p.Arg152His)
c.569-5440G>A (n.569-5440G>A)
n.960G>A
c.653G>A (p.Arg218His)
c.569-3206G>A (n.569-3206G>A)
c.458G>A (p.Arg153His)
c.74G>A (p.Arg25His)
c.524G>A (p.Arg175His)
 ClinVar dbSNP gnomAD v4 COSMIC
15g.66481788G>CCA392936183MAP2K1c.536G>C (p.Arg179Pro)
c.602G>C (p.Arg201Pro)
c.455G>C (p.Arg152Pro)
c.569-5440G>C (n.569-5440G>C)
n.960G>C
c.653G>C (p.Arg218Pro)
c.569-3206G>C (n.569-3206G>C)
c.458G>C (p.Arg153Pro)
c.74G>C (p.Arg25Pro)
c.524G>C (p.Arg175Pro)
 dbSNP
15g.66481788G>TCA392936184MAP2K1c.536G>T (p.Arg179Leu)
c.602G>T (p.Arg201Leu)
c.455G>T (p.Arg152Leu)
c.569-5440G>T (n.569-5440G>T)
n.960G>T
c.653G>T (p.Arg218Leu)
c.569-3206G>T (n.569-3206G>T)
c.458G>T (p.Arg153Leu)
c.74G>T (p.Arg25Leu)
c.524G>T (p.Arg175Leu)
 dbSNP
15g.66481789T>ACA490858400MAP2K1c.537T>A (p.Arg179=)
c.603T>A (p.Arg201=)
c.456T>A (p.Arg152=)
c.569-5439T>A (n.569-5439T>A)
n.961T>A
c.654T>A (p.Arg218=)
c.569-3205T>A (n.569-3205T>A)
c.459T>A (p.Arg153=)
c.75T>A (p.Arg25=)
c.525T>A (p.Arg175=)
 dbSNP
15g.66481789T>CCA490858401MAP2K1c.537T>C (p.Arg179=)
c.603T>C (p.Arg201=)
c.456T>C (p.Arg152=)
c.569-5439T>C (n.569-5439T>C)
n.961T>C
c.654T>C (p.Arg218=)
c.569-3205T>C (n.569-3205T>C)
c.459T>C (p.Arg153=)
c.75T>C (p.Arg25=)
c.525T>C (p.Arg175=)
 ClinVar dbSNP gnomAD v2 gnomAD v3 gnomAD v4
15g.66481789T>GCA490858399MAP2K1c.537T>G (p.Arg179=)
c.603T>G (p.Arg201=)
c.456T>G (p.Arg152=)
c.569-5439T>G (n.569-5439T>G)
n.961T>G
c.654T>G (p.Arg218=)
c.569-3205T>G (n.569-3205T>G)
c.459T>G (p.Arg153=)
c.75T>G (p.Arg25=)
c.525T>G (p.Arg175=)
15g.66481789T=CA2184097405MAP2K1c.537T= (p.Arg179=)
c.603T= (p.Arg201=)
c.456T= (p.Arg152=)
c.569-5439T= (n.569-5439T=)
n.961T=
c.654T= (p.Arg218=)
c.569-3205T= (n.569-3205T=)
c.459T= (p.Arg153=)
c.75T= (p.Arg25=)
c.525T= (p.Arg175=)
15g.66481790G>ACA392936185MAP2K1c.538G>A (p.Gly180Arg)
c.604G>A (p.Gly202Arg)
c.457G>A (p.Gly153Arg)
c.569-5438G>A (n.569-5438G>A)
n.962G>A
c.655G>A (p.Gly219Arg)
c.569-3204G>A (n.569-3204G>A)
c.460G>A (p.Gly154Arg)
c.76G>A (p.Gly26Arg)
c.526G>A (p.Gly176Arg)
 dbSNP
15g.66481790G>CCA392936187MAP2K1c.538G>C (p.Gly180Arg)
c.604G>C (p.Gly202Arg)
c.457G>C (p.Gly153Arg)
c.569-5438G>C (n.569-5438G>C)
n.962G>C
c.655G>C (p.Gly219Arg)
c.569-3204G>C (n.569-3204G>C)
c.460G>C (p.Gly154Arg)
c.76G>C (p.Gly26Arg)
c.526G>C (p.Gly176Arg)
 dbSNP
15g.66481790G>TCA392936189MAP2K1c.538G>T (p.Gly180Trp)
c.604G>T (p.Gly202Trp)
c.457G>T (p.Gly153Trp)
c.569-5438G>T (n.569-5438G>T)
n.962G>T
c.655G>T (p.Gly219Trp)
c.569-3204G>T (n.569-3204G>T)
c.460G>T (p.Gly154Trp)
c.76G>T (p.Gly26Trp)
c.526G>T (p.Gly176Trp)
 dbSNP
15g.66481791G>ACA392936194MAP2K1c.539G>A (p.Gly180Glu)
c.605G>A (p.Gly202Glu)
c.458G>A (p.Gly153Glu)
c.569-5437G>A (n.569-5437G>A)
n.963G>A
c.656G>A (p.Gly219Glu)
c.569-3203G>A (n.569-3203G>A)
c.461G>A (p.Gly154Glu)
c.77G>A (p.Gly26Glu)
c.527G>A (p.Gly176Glu)
 dbSNP
15g.66481791G>CCA392936192MAP2K1c.539G>C (p.Gly180Ala)
c.605G>C (p.Gly202Ala)
c.458G>C (p.Gly153Ala)
c.569-5437G>C (n.569-5437G>C)
n.963G>C
c.656G>C (p.Gly219Ala)
c.569-3203G>C (n.569-3203G>C)
c.461G>C (p.Gly154Ala)
c.77G>C (p.Gly26Ala)
c.527G>C (p.Gly176Ala)
 dbSNP
15g.66481791G>TCA392936191MAP2K1c.539G>T (p.Gly180Val)
c.605G>T (p.Gly202Val)
c.458G>T (p.Gly153Val)
c.569-5437G>T (n.569-5437G>T)
n.963G>T
c.656G>T (p.Gly219Val)
c.569-3203G>T (n.569-3203G>T)
c.461G>T (p.Gly154Val)
c.77G>T (p.Gly26Val)
c.527G>T (p.Gly176Val)
 dbSNP
15g.66481792G>ACA7623993MAP2K1c.540G>A (p.Gly180=)
c.606G>A (p.Gly202=)
c.459G>A (p.Gly153=)
c.569-5436G>A (n.569-5436G>A)
n.964G>A
c.657G>A (p.Gly219=)
c.569-3202G>A (n.569-3202G>A)
c.462G>A (p.Gly154=)
c.78G>A (p.Gly26=)
c.528G>A (p.Gly176=)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
15g.66481792G>CCA490858402MAP2K1c.540G>C (p.Gly180=)
c.606G>C (p.Gly202=)
c.459G>C (p.Gly153=)
c.569-5436G>C (n.569-5436G>C)
n.964G>C
c.657G>C (p.Gly219=)
c.569-3202G>C (n.569-3202G>C)
c.462G>C (p.Gly154=)
c.78G>C (p.Gly26=)
c.528G>C (p.Gly176=)
 dbSNP
15g.66481792G=CA2184097407MAP2K1c.540G= (p.Gly180=)
c.606G= (p.Gly202=)
c.459G= (p.Gly153=)
c.569-5436G= (n.569-5436G=)
n.964G=
c.657G= (p.Gly219=)
c.569-3202G= (n.569-3202G=)
c.462G= (p.Gly154=)
c.78G= (p.Gly26=)
c.528G= (p.Gly176=)
15g.66481792G>TCA490858403MAP2K1c.540G>T (p.Gly180=)
c.606G>T (p.Gly202=)
c.459G>T (p.Gly153=)
c.569-5436G>T (n.569-5436G>T)
n.964G>T
c.657G>T (p.Gly219=)
c.569-3202G>T (n.569-3202G>T)
c.462G>T (p.Gly154=)
c.78G>T (p.Gly26=)
c.528G>T (p.Gly176=)
 dbSNP
15g.66481793G>ACA16602457MAP2K1c.541G>A (p.Glu181Lys)
c.607G>A (p.Glu203Lys)
c.460G>A (p.Glu154Lys)
c.569-5435G>A (n.569-5435G>A)
n.965G>A
c.658G>A (p.Glu220Lys)
c.569-3201G>A (n.569-3201G>A)
c.463G>A (p.Glu155Lys)
c.79G>A (p.Glu27Lys)
c.529G>A (p.Glu177Lys)
 ClinVar dbSNP COSMIC
15g.66481793G>CCA392936198MAP2K1c.541G>C (p.Glu181Gln)
c.607G>C (p.Glu203Gln)
c.460G>C (p.Glu154Gln)
c.569-5435G>C (n.569-5435G>C)
n.965G>C
c.658G>C (p.Glu220Gln)
c.569-3201G>C (n.569-3201G>C)
c.463G>C (p.Glu155Gln)
c.79G>C (p.Glu27Gln)
c.529G>C (p.Glu177Gln)
 ClinVar dbSNP
15g.66481793G=CA2184097409MAP2K1c.541G= (p.Glu181=)
c.607G= (p.Glu203=)
c.460G= (p.Glu154=)
c.569-5435G= (n.569-5435G=)
n.965G=
c.658G= (p.Glu220=)
c.569-3201G= (n.569-3201G=)
c.463G= (p.Glu155=)
c.79G= (p.Glu27=)
c.529G= (p.Glu177=)
15g.66481793G>TCA392936200MAP2K1c.541G>T (p.Glu181Ter)
c.607G>T (p.Glu203Ter)
c.460G>T (p.Glu154Ter)
c.569-5435G>T (n.569-5435G>T)
n.965G>T
c.658G>T (p.Glu220Ter)
c.569-3201G>T (n.569-3201G>T)
c.463G>T (p.Glu155Ter)
c.79G>T (p.Glu27Ter)
c.529G>T (p.Glu177Ter)
 dbSNP
15g.66481794A=CA2184097414MAP2K1c.542A= (p.Glu181=)
c.608A= (p.Glu203=)
c.461A= (p.Glu154=)
c.569-5434A= (n.569-5434A=)
n.966A=
c.659A= (p.Glu220=)
c.569-3200A= (n.569-3200A=)
c.464A= (p.Glu155=)
c.80A= (p.Glu27=)
c.530A= (p.Glu177=)
15g.66481794A>CCA392936203MAP2K1c.542A>C (p.Glu181Ala)
c.608A>C (p.Glu203Ala)
c.461A>C (p.Glu154Ala)
c.569-5434A>C (n.569-5434A>C)
n.966A>C
c.659A>C (p.Glu220Ala)
c.569-3200A>C (n.569-3200A>C)
c.464A>C (p.Glu155Ala)
c.80A>C (p.Glu27Ala)
c.530A>C (p.Glu177Ala)
 ClinVar
15g.66481794A>GCA234222MAP2K1c.542A>G (p.Glu181Gly)
c.608A>G (p.Glu203Gly)
c.461A>G (p.Glu154Gly)
c.569-5434A>G (n.569-5434A>G)
n.966A>G
c.659A>G (p.Glu220Gly)
c.569-3200A>G (n.569-3200A>G)
c.464A>G (p.Glu155Gly)
c.80A>G (p.Glu27Gly)
c.530A>G (p.Glu177Gly)
 ClinVar dbSNP
15g.66481794A>TCA392936205MAP2K1c.542A>T (p.Glu181Val)
c.608A>T (p.Glu203Val)
c.461A>T (p.Glu154Val)
c.569-5434A>T (n.569-5434A>T)
n.966A>T
c.659A>T (p.Glu220Val)
c.569-3200A>T (n.569-3200A>T)
c.464A>T (p.Glu155Val)
c.80A>T (p.Glu27Val)
c.530A>T (p.Glu177Val)
 dbSNP COSMIC
15g.66481795G>ACA490858404MAP2K1c.543G>A (p.Glu181=)
c.609G>A (p.Glu203=)
c.462G>A (p.Glu154=)
c.569-5433G>A (n.569-5433G>A)
n.967G>A
c.660G>A (p.Glu220=)
c.569-3199G>A (n.569-3199G>A)
c.465G>A (p.Glu155=)
c.81G>A (p.Glu27=)
c.531G>A (p.Glu177=)
 dbSNP
15g.66481795G>CCA392936207MAP2K1c.543G>C (p.Glu181Asp)
c.609G>C (p.Glu203Asp)
c.462G>C (p.Glu154Asp)
c.569-5433G>C (n.569-5433G>C)
n.967G>C
c.660G>C (p.Glu220Asp)
c.569-3199G>C (n.569-3199G>C)
c.465G>C (p.Glu155Asp)
c.81G>C (p.Glu27Asp)
c.531G>C (p.Glu177Asp)
 dbSNP
15g.66481795G>TCA392936208MAP2K1c.543G>T (p.Glu181Asp)
c.609G>T (p.Glu203Asp)
c.462G>T (p.Glu154Asp)
c.569-5433G>T (n.569-5433G>T)
n.967G>T
c.660G>T (p.Glu220Asp)
c.569-3199G>T (n.569-3199G>T)
c.465G>T (p.Glu155Asp)
c.81G>T (p.Glu27Asp)
c.531G>T (p.Glu177Asp)
 dbSNP
15g.66481796A>CCA392936210MAP2K1c.544A>C (p.Ile182Leu)
c.610A>C (p.Ile204Leu)
c.463A>C (p.Ile155Leu)
c.569-5432A>C (n.569-5432A>C)
n.968A>C
c.661A>C (p.Ile221Leu)
c.569-3198A>C (n.569-3198A>C)
c.466A>C (p.Ile156Leu)
c.82A>C (p.Ile28Leu)
c.532A>C (p.Ile178Leu)
 dbSNP
15g.66481796A>GCA392936212MAP2K1c.544A>G (p.Ile182Val)
c.610A>G (p.Ile204Val)
c.463A>G (p.Ile155Val)
c.569-5432A>G (n.569-5432A>G)
n.968A>G
c.661A>G (p.Ile221Val)
c.569-3198A>G (n.569-3198A>G)
c.466A>G (p.Ile156Val)
c.82A>G (p.Ile28Val)
c.532A>G (p.Ile178Val)
 dbSNP
15g.66481796A>TCA392936214MAP2K1c.544A>T (p.Ile182Phe)
c.610A>T (p.Ile204Phe)
c.463A>T (p.Ile155Phe)
c.569-5432A>T (n.569-5432A>T)
n.968A>T
c.661A>T (p.Ile221Phe)
c.569-3198A>T (n.569-3198A>T)
c.466A>T (p.Ile156Phe)
c.82A>T (p.Ile28Phe)
c.532A>T (p.Ile178Phe)
 dbSNP
15g.66481797T>ACA392936218MAP2K1c.545T>A (p.Ile182Asn)
c.611T>A (p.Ile204Asn)
c.464T>A (p.Ile155Asn)
c.569-5431T>A (n.569-5431T>A)
n.969T>A
c.662T>A (p.Ile221Asn)
c.569-3197T>A (n.569-3197T>A)
c.467T>A (p.Ile156Asn)
c.83T>A (p.Ile28Asn)
c.533T>A (p.Ile178Asn)
 dbSNP
15g.66481797T>CCA392936220MAP2K1c.545T>C (p.Ile182Thr)
c.611T>C (p.Ile204Thr)
c.464T>C (p.Ile155Thr)
c.569-5431T>C (n.569-5431T>C)
n.969T>C
c.662T>C (p.Ile221Thr)
c.569-3197T>C (n.569-3197T>C)
c.467T>C (p.Ile156Thr)
c.83T>C (p.Ile28Thr)
c.533T>C (p.Ile178Thr)
 dbSNP COSMIC
15g.66481797T>GCA392936216MAP2K1c.545T>G (p.Ile182Ser)
c.611T>G (p.Ile204Ser)
c.464T>G (p.Ile155Ser)
c.569-5431T>G (n.569-5431T>G)
n.969T>G
c.662T>G (p.Ile221Ser)
c.569-3197T>G (n.569-3197T>G)
c.467T>G (p.Ile156Ser)
c.83T>G (p.Ile28Ser)
c.533T>G (p.Ile178Ser)
 dbSNP
15g.66481798C>ACA490858406MAP2K1c.546C>A (p.Ile182=)
c.612C>A (p.Ile204=)
c.465C>A (p.Ile155=)
c.569-5430C>A (n.569-5430C>A)
n.970C>A
c.663C>A (p.Ile221=)
c.569-3196C>A (n.569-3196C>A)
c.468C>A (p.Ile156=)
c.84C>A (p.Ile28=)
c.534C>A (p.Ile178=)
 ClinVar dbSNP
15g.66481798C>GCA392936222MAP2K1c.546C>G (p.Ile182Met)
c.612C>G (p.Ile204Met)
c.465C>G (p.Ile155Met)
c.569-5430C>G (n.569-5430C>G)
n.970C>G
c.663C>G (p.Ile221Met)
c.569-3196C>G (n.569-3196C>G)
c.468C>G (p.Ile156Met)
c.84C>G (p.Ile28Met)
c.534C>G (p.Ile178Met)
 ClinVar dbSNP
15g.66481798C>TCA490858405MAP2K1c.546C>T (p.Ile182=)
c.612C>T (p.Ile204=)
c.465C>T (p.Ile155=)
c.569-5430C>T (n.569-5430C>T)
n.970C>T
c.663C>T (p.Ile221=)
c.569-3196C>T (n.569-3196C>T)
c.468C>T (p.Ile156=)
c.84C>T (p.Ile28=)
c.534C>T (p.Ile178=)
 dbSNP
15g.66481799A>CCA392936224MAP2K1c.547A>C (p.Lys183Gln)
c.613A>C (p.Lys205Gln)
c.466A>C (p.Lys156Gln)
c.569-5429A>C (n.569-5429A>C)
n.971A>C
c.664A>C (p.Lys222Gln)
c.569-3195A>C (n.569-3195A>C)
c.469A>C (p.Lys157Gln)
c.85A>C (p.Lys29Gln)
c.535A>C (p.Lys179Gln)
15g.66481799A>GCA392936226MAP2K1c.547A>G (p.Lys183Glu)
c.613A>G (p.Lys205Glu)
c.466A>G (p.Lys156Glu)
c.569-5429A>G (n.569-5429A>G)
n.971A>G
c.664A>G (p.Lys222Glu)
c.569-3195A>G (n.569-3195A>G)
c.469A>G (p.Lys157Glu)
c.85A>G (p.Lys29Glu)
c.535A>G (p.Lys179Glu)
 dbSNP
15g.66481799A>TCA392936228MAP2K1c.547A>T (p.Lys183Ter)
c.613A>T (p.Lys205Ter)
c.466A>T (p.Lys156Ter)
c.569-5429A>T (n.569-5429A>T)
n.971A>T
c.664A>T (p.Lys222Ter)
c.569-3195A>T (n.569-3195A>T)
c.469A>T (p.Lys157Ter)
c.85A>T (p.Lys29Ter)
c.535A>T (p.Lys179Ter)
 dbSNP
15g.66481800A>CCA392936234MAP2K1c.548A>C (p.Lys183Thr)
c.614A>C (p.Lys205Thr)
c.467A>C (p.Lys156Thr)
c.569-5428A>C (n.569-5428A>C)
n.972A>C
c.665A>C (p.Lys222Thr)
c.569-3194A>C (n.569-3194A>C)
c.470A>C (p.Lys157Thr)
c.86A>C (p.Lys29Thr)
c.536A>C (p.Lys179Thr)
15g.66481800A>GCA392936232MAP2K1c.548A>G (p.Lys183Arg)
c.614A>G (p.Lys205Arg)
c.467A>G (p.Lys156Arg)
c.569-5428A>G (n.569-5428A>G)
n.972A>G
c.665A>G (p.Lys222Arg)
c.569-3194A>G (n.569-3194A>G)
c.470A>G (p.Lys157Arg)
c.86A>G (p.Lys29Arg)
c.536A>G (p.Lys179Arg)
 dbSNP
15g.66481800A>TCA392936230MAP2K1c.548A>T (p.Lys183Met)
c.614A>T (p.Lys205Met)
c.467A>T (p.Lys156Met)
c.569-5428A>T (n.569-5428A>T)
n.972A>T
c.665A>T (p.Lys222Met)
c.569-3194A>T (n.569-3194A>T)
c.470A>T (p.Lys157Met)
c.86A>T (p.Lys29Met)
c.536A>T (p.Lys179Met)
 dbSNP
15g.66481801G>ACA7623994MAP2K1c.549G>A (p.Lys183=)
c.615G>A (p.Lys205=)
c.468G>A (p.Lys156=)
c.569-5427G>A (n.569-5427G>A)
n.973G>A
c.666G>A (p.Lys222=)
c.569-3193G>A (n.569-3193G>A)
c.471G>A (p.Lys157=)
c.87G>A (p.Lys29=)
c.537G>A (p.Lys179=)
 dbSNP ExAC gnomAD v2 gnomAD v4
15g.66481801G>CCA392936236MAP2K1c.549G>C (p.Lys183Asn)
c.615G>C (p.Lys205Asn)
c.468G>C (p.Lys156Asn)
c.569-5427G>C (n.569-5427G>C)
n.973G>C
c.666G>C (p.Lys222Asn)
c.569-3193G>C (n.569-3193G>C)
c.471G>C (p.Lys157Asn)
c.87G>C (p.Lys29Asn)
c.537G>C (p.Lys179Asn)
 dbSNP
15g.66481801G=CA2184097415MAP2K1c.549G= (p.Lys183=)
c.615G= (p.Lys205=)
c.468G= (p.Lys156=)
c.569-5427G= (n.569-5427G=)
n.973G=
c.666G= (p.Lys222=)
c.569-3193G= (n.569-3193G=)
c.471G= (p.Lys157=)
c.87G= (p.Lys29=)
c.537G= (p.Lys179=)
15g.66481801G>TCA392936237MAP2K1c.549G>T (p.Lys183Asn)
c.615G>T (p.Lys205Asn)
c.468G>T (p.Lys156Asn)
c.569-5427G>T (n.569-5427G>T)
n.973G>T
c.666G>T (p.Lys222Asn)
c.569-3193G>T (n.569-3193G>T)
c.471G>T (p.Lys157Asn)
c.87G>T (p.Lys29Asn)
c.537G>T (p.Lys179Asn)
15g.66481802C>ACA392936240MAP2K1c.550C>A (p.Leu184Ile)
c.616C>A (p.Leu206Ile)
c.469C>A (p.Leu157Ile)
c.569-5426C>A (n.569-5426C>A)
n.974C>A
c.667C>A (p.Leu223Ile)
c.569-3192C>A (n.569-3192C>A)
c.472C>A (p.Leu158Ile)
c.88C>A (p.Leu30Ile)
c.538C>A (p.Leu180Ile)
 dbSNP
15g.66481802C>GCA392936241MAP2K1c.550C>G (p.Leu184Val)
c.616C>G (p.Leu206Val)
c.469C>G (p.Leu157Val)
c.569-5426C>G (n.569-5426C>G)
n.974C>G
c.667C>G (p.Leu223Val)
c.569-3192C>G (n.569-3192C>G)
c.472C>G (p.Leu158Val)
c.88C>G (p.Leu30Val)
c.538C>G (p.Leu180Val)
 dbSNP
15g.66481802C>TCA392936242MAP2K1c.550C>T (p.Leu184Phe)
c.616C>T (p.Leu206Phe)
c.469C>T (p.Leu157Phe)
c.569-5426C>T (n.569-5426C>T)
n.974C>T
c.667C>T (p.Leu223Phe)
c.569-3192C>T (n.569-3192C>T)
c.472C>T (p.Leu158Phe)
c.88C>T (p.Leu30Phe)
c.538C>T (p.Leu180Phe)
15g.66481803T>ACA392936245MAP2K1c.551T>A (p.Leu184His)
c.617T>A (p.Leu206His)
c.470T>A (p.Leu157His)
c.569-5425T>A (n.569-5425T>A)
n.975T>A
c.668T>A (p.Leu223His)
c.569-3191T>A (n.569-3191T>A)
c.473T>A (p.Leu158His)
c.89T>A (p.Leu30His)
c.539T>A (p.Leu180His)
 dbSNP
15g.66481803T>CCA392936249MAP2K1c.551T>C (p.Leu184Pro)
c.617T>C (p.Leu206Pro)
c.470T>C (p.Leu157Pro)
c.569-5425T>C (n.569-5425T>C)
n.975T>C
c.668T>C (p.Leu223Pro)
c.569-3191T>C (n.569-3191T>C)
c.473T>C (p.Leu158Pro)
c.89T>C (p.Leu30Pro)
c.539T>C (p.Leu180Pro)
15g.66481803T>GCA392936247MAP2K1c.551T>G (p.Leu184Arg)
c.617T>G (p.Leu206Arg)
c.470T>G (p.Leu157Arg)
c.569-5425T>G (n.569-5425T>G)
n.975T>G
c.668T>G (p.Leu223Arg)
c.569-3191T>G (n.569-3191T>G)
c.473T>G (p.Leu158Arg)
c.89T>G (p.Leu30Arg)
c.539T>G (p.Leu180Arg)
15g.66481804C>ACA490858407MAP2K1c.552C>A (p.Leu184=)
c.618C>A (p.Leu206=)
c.471C>A (p.Leu157=)
c.569-5424C>A (n.569-5424C>A)
n.976C>A
c.669C>A (p.Leu223=)
c.569-3190C>A (n.569-3190C>A)
c.474C>A (p.Leu158=)
c.90C>A (p.Leu30=)
c.540C>A (p.Leu180=)
 gnomAD v4
15g.66481804C>GCA490858408MAP2K1c.552C>G (p.Leu184=)
c.618C>G (p.Leu206=)
c.471C>G (p.Leu157=)
c.569-5424C>G (n.569-5424C>G)
n.976C>G
c.669C>G (p.Leu223=)
c.569-3190C>G (n.569-3190C>G)
c.474C>G (p.Leu158=)
c.90C>G (p.Leu30=)
c.540C>G (p.Leu180=)
 dbSNP
15g.66481804C>TCA490858409MAP2K1c.552C>T (p.Leu184=)
c.618C>T (p.Leu206=)
c.471C>T (p.Leu157=)
c.569-5424C>T (n.569-5424C>T)
n.976C>T
c.669C>T (p.Leu223=)
c.569-3190C>T (n.569-3190C>T)
c.474C>T (p.Leu158=)
c.90C>T (p.Leu30=)
c.540C>T (p.Leu180=)
 ClinVar dbSNP
15g.66481805T>ACA392936251MAP2K1c.553T>A (p.Cys185Ser)
c.619T>A (p.Cys207Ser)
c.472T>A (p.Cys158Ser)
c.569-5423T>A (n.569-5423T>A)
n.977T>A
c.670T>A (p.Cys224Ser)
c.569-3189T>A (n.569-3189T>A)
c.475T>A (p.Cys159Ser)
c.91T>A (p.Cys31Ser)
c.541T>A (p.Cys181Ser)
 dbSNP
15g.66481805T>CCA392936255MAP2K1c.553T>C (p.Cys185Arg)
c.619T>C (p.Cys207Arg)
c.472T>C (p.Cys158Arg)
c.569-5423T>C (n.569-5423T>C)
n.977T>C
c.670T>C (p.Cys224Arg)
c.569-3189T>C (n.569-3189T>C)
c.475T>C (p.Cys159Arg)
c.91T>C (p.Cys31Arg)
c.541T>C (p.Cys181Arg)
 dbSNP
15g.66481805T>GCA392936253MAP2K1c.553T>G (p.Cys185Gly)
c.619T>G (p.Cys207Gly)
c.472T>G (p.Cys158Gly)
c.569-5423T>G (n.569-5423T>G)
n.977T>G
c.670T>G (p.Cys224Gly)
c.569-3189T>G (n.569-3189T>G)
c.475T>G (p.Cys159Gly)
c.91T>G (p.Cys31Gly)
c.541T>G (p.Cys181Gly)
15g.66481806delCA2629083409MAP2K1c.554del (p.Cys185LeufsTer?)
c.620del (p.Cys207LeufsTer?)
c.473del (p.Cys158LeufsTer?)
c.569-5422del (n.569-5422del)
n.978del
c.671del (p.Cys224LeufsTer?)
c.569-3188del (n.569-3188del)
c.476del (p.Cys159LeufsTer?)
c.92del (p.Cys31LeufsTer?)
c.542del (p.Cys181LeufsTer?)
 gnomAD v4
15g.66481806G>ACA392936257MAP2K1c.554G>A (p.Cys185Tyr)
c.620G>A (p.Cys207Tyr)
c.473G>A (p.Cys158Tyr)
c.569-5422G>A (n.569-5422G>A)
n.978G>A
c.671G>A (p.Cys224Tyr)
c.569-3188G>A (n.569-3188G>A)
c.476G>A (p.Cys159Tyr)
c.92G>A (p.Cys31Tyr)
c.542G>A (p.Cys181Tyr)
 dbSNP
15g.66481806G>CCA392936258MAP2K1c.554G>C (p.Cys185Ser)
c.620G>C (p.Cys207Ser)
c.473G>C (p.Cys158Ser)
c.569-5422G>C (n.569-5422G>C)
n.978G>C
c.671G>C (p.Cys224Ser)
c.569-3188G>C (n.569-3188G>C)
c.476G>C (p.Cys159Ser)
c.92G>C (p.Cys31Ser)
c.542G>C (p.Cys181Ser)
 dbSNP
15g.66481806G>TCA392936261MAP2K1c.554G>T (p.Cys185Phe)
c.620G>T (p.Cys207Phe)
c.473G>T (p.Cys158Phe)
c.569-5422G>T (n.569-5422G>T)
n.978G>T
c.671G>T (p.Cys224Phe)
c.569-3188G>T (n.569-3188G>T)
c.476G>T (p.Cys159Phe)
c.92G>T (p.Cys31Phe)
c.542G>T (p.Cys181Phe)
15g.66481807T>ACA392936263MAP2K1c.555T>A (p.Cys185Ter)
c.621T>A (p.Cys207Ter)
c.474T>A (p.Cys158Ter)
c.569-5421T>A (n.569-5421T>A)
n.979T>A
c.672T>A (p.Cys224Ter)
c.569-3187T>A (n.569-3187T>A)
c.477T>A (p.Cys159Ter)
c.93T>A (p.Cys31Ter)
c.543T>A (p.Cys181Ter)
 dbSNP
15g.66481807T>CCA490858410MAP2K1c.555T>C (p.Cys185=)
c.621T>C (p.Cys207=)
c.474T>C (p.Cys158=)
c.569-5421T>C (n.569-5421T>C)
n.979T>C
c.672T>C (p.Cys224=)
c.569-3187T>C (n.569-3187T>C)
c.477T>C (p.Cys159=)
c.93T>C (p.Cys31=)
c.543T>C (p.Cys181=)
 dbSNP
15g.66481807T>GCA392936264MAP2K1c.555T>G (p.Cys185Trp)
c.621T>G (p.Cys207Trp)
c.474T>G (p.Cys158Trp)
c.569-5421T>G (n.569-5421T>G)
n.979T>G
c.672T>G (p.Cys224Trp)
c.569-3187T>G (n.569-3187T>G)
c.477T>G (p.Cys159Trp)
c.93T>G (p.Cys31Trp)
c.543T>G (p.Cys181Trp)
 dbSNP
15g.66481808G>ACA392936271MAP2K1c.556G>A (p.Asp186Asn)
c.622G>A (p.Asp208Asn)
c.475G>A (p.Asp159Asn)
c.569-5420G>A (n.569-5420G>A)
n.980G>A
c.673G>A (p.Asp225Asn)
c.569-3186G>A (n.569-3186G>A)
c.478G>A (p.Asp160Asn)
c.94G>A (p.Asp32Asn)
c.544G>A (p.Asp182Asn)
 dbSNP
15g.66481808G>CCA392936269MAP2K1c.556G>C (p.Asp186His)
c.622G>C (p.Asp208His)
c.475G>C (p.Asp159His)
c.569-5420G>C (n.569-5420G>C)
n.980G>C
c.673G>C (p.Asp225His)
c.569-3186G>C (n.569-3186G>C)
c.478G>C (p.Asp160His)
c.94G>C (p.Asp32His)
c.544G>C (p.Asp182His)
 dbSNP
15g.66481808G>TCA392936267MAP2K1c.556G>T (p.Asp186Tyr)
c.622G>T (p.Asp208Tyr)
c.475G>T (p.Asp159Tyr)
c.569-5420G>T (n.569-5420G>T)
n.980G>T
c.673G>T (p.Asp225Tyr)
c.569-3186G>T (n.569-3186G>T)
c.478G>T (p.Asp160Tyr)
c.94G>T (p.Asp32Tyr)
c.544G>T (p.Asp182Tyr)
15g.66481809A>CCA392936273MAP2K1c.557A>C (p.Asp186Ala)
c.623A>C (p.Asp208Ala)
c.476A>C (p.Asp159Ala)
c.569-5419A>C (n.569-5419A>C)
n.981A>C
c.674A>C (p.Asp225Ala)
c.569-3185A>C (n.569-3185A>C)
c.479A>C (p.Asp160Ala)
c.95A>C (p.Asp32Ala)
c.545A>C (p.Asp182Ala)
 dbSNP
15g.66481809A>GCA392936275MAP2K1c.557A>G (p.Asp186Gly)
c.623A>G (p.Asp208Gly)
c.476A>G (p.Asp159Gly)
c.569-5419A>G (n.569-5419A>G)
n.981A>G
c.674A>G (p.Asp225Gly)
c.569-3185A>G (n.569-3185A>G)
c.479A>G (p.Asp160Gly)
c.95A>G (p.Asp32Gly)
c.545A>G (p.Asp182Gly)
 dbSNP
15g.66481809A>TCA392936277MAP2K1c.557A>T (p.Asp186Val)
c.623A>T (p.Asp208Val)
c.476A>T (p.Asp159Val)
c.569-5419A>T (n.569-5419A>T)
n.981A>T
c.674A>T (p.Asp225Val)
c.569-3185A>T (n.569-3185A>T)
c.479A>T (p.Asp160Val)
c.95A>T (p.Asp32Val)
c.545A>T (p.Asp182Val)
 dbSNP
15g.66481810C>ACA392936279MAP2K1c.558C>A (p.Asp186Glu)
c.624C>A (p.Asp208Glu)
c.477C>A (p.Asp159Glu)
c.569-5418C>A (n.569-5418C>A)
n.982C>A
c.675C>A (p.Asp225Glu)
c.569-3184C>A (n.569-3184C>A)
c.480C>A (p.Asp160Glu)
c.96C>A (p.Asp32Glu)
c.546C>A (p.Asp182Glu)
 dbSNP
15g.66481810C=CA2184097417MAP2K1c.558C= (p.Asp186=)
c.624C= (p.Asp208=)
c.477C= (p.Asp159=)
c.569-5418C= (n.569-5418C=)
n.982C=
c.675C= (p.Asp225=)
c.569-3184C= (n.569-3184C=)
c.480C= (p.Asp160=)
c.96C= (p.Asp32=)
c.546C= (p.Asp182=)
15g.66481810C>GCA392936281MAP2K1c.558C>G (p.Asp186Glu)
c.624C>G (p.Asp208Glu)
c.477C>G (p.Asp159Glu)
c.569-5418C>G (n.569-5418C>G)
n.982C>G
c.675C>G (p.Asp225Glu)
c.569-3184C>G (n.569-3184C>G)
c.480C>G (p.Asp160Glu)
c.96C>G (p.Asp32Glu)
c.546C>G (p.Asp182Glu)
15g.66481810C>TCA7623995MAP2K1c.558C>T (p.Asp186=)
c.624C>T (p.Asp208=)
c.477C>T (p.Asp159=)
c.569-5418C>T (n.569-5418C>T)
n.982C>T
c.675C>T (p.Asp225=)
c.569-3184C>T (n.569-3184C>T)
c.480C>T (p.Asp160=)
c.96C>T (p.Asp32=)
c.546C>T (p.Asp182=)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
15g.66481811T>ACA392936288MAP2K1c.559T>A (p.Phe187Ile)
c.625T>A (p.Phe209Ile)
c.478T>A (p.Phe160Ile)
c.569-5417T>A (n.569-5417T>A)
n.983T>A
c.676T>A (p.Phe226Ile)
c.569-3183T>A (n.569-3183T>A)
c.481T>A (p.Phe161Ile)
c.97T>A (p.Phe33Ile)
c.547T>A (p.Phe183Ile)
 dbSNP
15g.66481811T>CCA392936285MAP2K1c.559T>C (p.Phe187Leu)
c.625T>C (p.Phe209Leu)
c.478T>C (p.Phe160Leu)
c.569-5417T>C (n.569-5417T>C)
n.983T>C
c.676T>C (p.Phe226Leu)
c.569-3183T>C (n.569-3183T>C)
c.481T>C (p.Phe161Leu)
c.97T>C (p.Phe33Leu)
c.547T>C (p.Phe183Leu)
15g.66481811T>GCA392936286MAP2K1c.559T>G (p.Phe187Val)
c.625T>G (p.Phe209Val)
c.478T>G (p.Phe160Val)
c.569-5417T>G (n.569-5417T>G)
n.983T>G
c.676T>G (p.Phe226Val)
c.569-3183T>G (n.569-3183T>G)
c.481T>G (p.Phe161Val)
c.97T>G (p.Phe33Val)
c.547T>G (p.Phe183Val)
15g.66481812T>ACA392936289MAP2K1c.560T>A (p.Phe187Tyr)
c.626T>A (p.Phe209Tyr)
c.479T>A (p.Phe160Tyr)
c.569-5416T>A (n.569-5416T>A)
n.984T>A
c.677T>A (p.Phe226Tyr)
c.569-3182T>A (n.569-3182T>A)
c.482T>A (p.Phe161Tyr)
c.98T>A (p.Phe33Tyr)
c.548T>A (p.Phe183Tyr)
 dbSNP
15g.66481812T>CCA392936291MAP2K1c.560T>C (p.Phe187Ser)
c.626T>C (p.Phe209Ser)
c.479T>C (p.Phe160Ser)
c.569-5416T>C (n.569-5416T>C)
n.984T>C
c.677T>C (p.Phe226Ser)
c.569-3182T>C (n.569-3182T>C)
c.482T>C (p.Phe161Ser)
c.98T>C (p.Phe33Ser)
c.548T>C (p.Phe183Ser)
15g.66481812T>GCA392936292MAP2K1c.560T>G (p.Phe187Cys)
c.626T>G (p.Phe209Cys)
c.479T>G (p.Phe160Cys)
c.569-5416T>G (n.569-5416T>G)
n.984T>G
c.677T>G (p.Phe226Cys)
c.569-3182T>G (n.569-3182T>G)
c.482T>G (p.Phe161Cys)
c.98T>G (p.Phe33Cys)
c.548T>G (p.Phe183Cys)
15g.66481813T>ACA392936294MAP2K1c.561T>A (p.Phe187Leu)
c.627T>A (p.Phe209Leu)
c.480T>A (p.Phe160Leu)
c.569-5415T>A (n.569-5415T>A)
n.985T>A
c.678T>A (p.Phe226Leu)
c.569-3181T>A (n.569-3181T>A)
c.483T>A (p.Phe161Leu)
c.99T>A (p.Phe33Leu)
c.549T>A (p.Phe183Leu)
15g.66481813T>CCA271671668MAP2K1c.561T>C (p.Phe187=)
c.627T>C (p.Phe209=)
c.480T>C (p.Phe160=)
c.569-5415T>C (n.569-5415T>C)
n.985T>C
c.678T>C (p.Phe226=)
c.569-3181T>C (n.569-3181T>C)
c.483T>C (p.Phe161=)
c.99T>C (p.Phe33=)
c.549T>C (p.Phe183=)
 dbSNP
15g.66481813T>GCA392936297MAP2K1c.561T>G (p.Phe187Leu)
c.627T>G (p.Phe209Leu)
c.480T>G (p.Phe160Leu)
c.569-5415T>G (n.569-5415T>G)
n.985T>G
c.678T>G (p.Phe226Leu)
c.569-3181T>G (n.569-3181T>G)
c.483T>G (p.Phe161Leu)
c.99T>G (p.Phe33Leu)
c.549T>G (p.Phe183Leu)
 gnomAD v4
15g.66481813T=CA2184097420MAP2K1c.561T= (p.Phe187=)
c.627T= (p.Phe209=)
c.480T= (p.Phe160=)
c.569-5415T= (n.569-5415T=)
n.985T=
c.678T= (p.Phe226=)
c.569-3181T= (n.569-3181T=)
c.483T= (p.Phe161=)
c.99T= (p.Phe33=)
c.549T= (p.Phe183=)
15g.66481814G>ACA392936300MAP2K1c.562G>A (p.Gly188Arg)
c.628G>A (p.Gly210Arg)
c.481G>A (p.Gly161Arg)
c.569-5414G>A (n.569-5414G>A)
n.986G>A
c.679G>A (p.Gly227Arg)
c.569-3180G>A (n.569-3180G>A)
c.484G>A (p.Gly162Arg)
c.100G>A (p.Gly34Arg)
c.550G>A (p.Gly184Arg)
 dbSNP
15g.66481814G>CCA392936302MAP2K1c.562G>C (p.Gly188Arg)
c.628G>C (p.Gly210Arg)
c.481G>C (p.Gly161Arg)
c.569-5414G>C (n.569-5414G>C)
n.986G>C
c.679G>C (p.Gly227Arg)
c.569-3180G>C (n.569-3180G>C)
c.484G>C (p.Gly162Arg)
c.100G>C (p.Gly34Arg)
c.550G>C (p.Gly184Arg)
 ClinVar dbSNP
15g.66481814G>TCA392936304MAP2K1c.562G>T (p.Gly188Trp)
c.628G>T (p.Gly210Trp)
c.481G>T (p.Gly161Trp)
c.569-5414G>T (n.569-5414G>T)
n.986G>T
c.679G>T (p.Gly227Trp)
c.569-3180G>T (n.569-3180G>T)
c.484G>T (p.Gly162Trp)
c.100G>T (p.Gly34Trp)
c.550G>T (p.Gly184Trp)
 dbSNP
15g.66481815G>ACA392936306MAP2K1c.563G>A (p.Gly188Glu)
c.629G>A (p.Gly210Glu)
c.482G>A (p.Gly161Glu)
c.569-5413G>A (n.569-5413G>A)
n.987G>A
c.680G>A (p.Gly227Glu)
c.569-3179G>A (n.569-3179G>A)
c.485G>A (p.Gly162Glu)
c.101G>A (p.Gly34Glu)
c.551G>A (p.Gly184Glu)
 dbSNP
15g.66481815G>CCA392936307MAP2K1c.563G>C (p.Gly188Ala)
c.629G>C (p.Gly210Ala)
c.482G>C (p.Gly161Ala)
c.569-5413G>C (n.569-5413G>C)
n.987G>C
c.680G>C (p.Gly227Ala)
c.569-3179G>C (n.569-3179G>C)
c.485G>C (p.Gly162Ala)
c.101G>C (p.Gly34Ala)
c.551G>C (p.Gly184Ala)
 dbSNP
15g.66481815G>TCA392936309MAP2K1c.563G>T (p.Gly188Val)
c.629G>T (p.Gly210Val)
c.482G>T (p.Gly161Val)
c.569-5413G>T (n.569-5413G>T)
n.987G>T
c.680G>T (p.Gly227Val)
c.569-3179G>T (n.569-3179G>T)
c.485G>T (p.Gly162Val)
c.101G>T (p.Gly34Val)
c.551G>T (p.Gly184Val)
 dbSNP
15g.66481816G>ACA490858412MAP2K1c.564G>A (p.Gly188=)
c.630G>A (p.Gly210=)
c.483G>A (p.Gly161=)
c.569-5412G>A (n.569-5412G>A)
n.988G>A
c.681G>A (p.Gly227=)
c.569-3178G>A (n.569-3178G>A)
c.486G>A (p.Gly162=)
c.102G>A (p.Gly34=)
c.552G>A (p.Gly184=)
 ClinVar dbSNP gnomAD v4
15g.66481816G>CCA490858411MAP2K1c.564G>C (p.Gly188=)
c.630G>C (p.Gly210=)
c.483G>C (p.Gly161=)
c.569-5412G>C (n.569-5412G>C)
n.988G>C
c.681G>C (p.Gly227=)
c.569-3178G>C (n.569-3178G>C)
c.486G>C (p.Gly162=)
c.102G>C (p.Gly34=)
c.552G>C (p.Gly184=)
 dbSNP
15g.66481816G=CA2184097422MAP2K1c.564G= (p.Gly188=)
c.630G= (p.Gly210=)
c.483G= (p.Gly161=)
c.569-5412G= (n.569-5412G=)
n.988G=
c.681G= (p.Gly227=)
c.569-3178G= (n.569-3178G=)
c.486G= (p.Gly162=)
c.102G= (p.Gly34=)
c.552G= (p.Gly184=)
15g.66481816G>TCA490858413MAP2K1c.564G>T (p.Gly188=)
c.630G>T (p.Gly210=)
c.483G>T (p.Gly161=)
c.569-5412G>T (n.569-5412G>T)
n.988G>T
c.681G>T (p.Gly227=)
c.569-3178G>T (n.569-3178G>T)
c.486G>T (p.Gly162=)
c.102G>T (p.Gly34=)
c.552G>T (p.Gly184=)
 dbSNP gnomAD v4
15g.66481817G>ACA185378MAP2K1c.565G>A (p.Val189Ile)
c.631G>A (p.Val211Ile)
c.484G>A (p.Val162Ile)
c.569-5411G>A (n.569-5411G>A)
n.989G>A
c.682G>A (p.Val228Ile)
c.569-3177G>A (n.569-3177G>A)
c.487G>A (p.Val163Ile)
c.103G>A (p.Val35Ile)
c.553G>A (p.Val185Ile)
 ClinVar dbSNP gnomAD v3 gnomAD v4
15g.66481817G>CCA392936313MAP2K1c.565G>C (p.Val189Leu)
c.631G>C (p.Val211Leu)
c.484G>C (p.Val162Leu)
c.569-5411G>C (n.569-5411G>C)
n.989G>C
c.682G>C (p.Val228Leu)
c.569-3177G>C (n.569-3177G>C)
c.487G>C (p.Val163Leu)
c.103G>C (p.Val35Leu)
c.553G>C (p.Val185Leu)
 dbSNP
15g.66481817G=CA2184097424MAP2K1c.565G= (p.Val189=)
c.631G= (p.Val211=)
c.484G= (p.Val162=)
c.569-5411G= (n.569-5411G=)
n.989G=
c.682G= (p.Val228=)
c.569-3177G= (n.569-3177G=)
c.487G= (p.Val163=)
c.103G= (p.Val35=)
c.553G= (p.Val185=)
15g.66481817G>TCA392936312MAP2K1c.565G>T (p.Val189Phe)
c.631G>T (p.Val211Phe)
c.484G>T (p.Val162Phe)
c.569-5411G>T (n.569-5411G>T)
n.989G>T
c.682G>T (p.Val228Phe)
c.569-3177G>T (n.569-3177G>T)
c.487G>T (p.Val163Phe)
c.103G>T (p.Val35Phe)
c.553G>T (p.Val185Phe)
 dbSNP
15g.66481818T>ACA16602653MAP2K1c.566T>A (p.Val189Asp)
c.632T>A (p.Val211Asp)
c.485T>A (p.Val162Asp)
c.569-5410T>A (n.569-5410T>A)
n.990T>A
c.683T>A (p.Val228Asp)
c.569-3176T>A (n.569-3176T>A)
c.488T>A (p.Val163Asp)
c.104T>A (p.Val35Asp)
c.554T>A (p.Val185Asp)
 ClinVar dbSNP
15g.66481818T>CCA392936316MAP2K1c.566T>C (p.Val189Ala)
c.632T>C (p.Val211Ala)
c.485T>C (p.Val162Ala)
c.569-5410T>C (n.569-5410T>C)
n.990T>C
c.683T>C (p.Val228Ala)
c.569-3176T>C (n.569-3176T>C)
c.488T>C (p.Val163Ala)
c.104T>C (p.Val35Ala)
c.554T>C (p.Val185Ala)
 dbSNP
15g.66481818T>GCA392936317MAP2K1c.566T>G (p.Val189Gly)
c.632T>G (p.Val211Gly)
c.485T>G (p.Val162Gly)
c.569-5410T>G (n.569-5410T>G)
n.990T>G
c.683T>G (p.Val228Gly)
c.569-3176T>G (n.569-3176T>G)
c.488T>G (p.Val163Gly)
c.104T>G (p.Val35Gly)
c.554T>G (p.Val185Gly)
 dbSNP
15g.66481818T=CA2184097428MAP2K1c.566T= (p.Val189=)
c.632T= (p.Val211=)
c.485T= (p.Val162=)
c.569-5410T= (n.569-5410T=)
n.990T=
c.683T= (p.Val228=)
c.569-3176T= (n.569-3176T=)
c.488T= (p.Val163=)
c.104T= (p.Val35=)
c.554T= (p.Val185=)
15g.66481819C>ACA490858414MAP2K1c.567C>A (p.Val189=)
c.633C>A (p.Val211=)
c.486C>A (p.Val162=)
c.569-5409C>A (n.569-5409C>A)
n.991C>A
c.684C>A (p.Val228=)
c.569-3175C>A (n.569-3175C>A)
c.489C>A (p.Val163=)
c.105C>A (p.Val35=)
c.555C>A (p.Val185=)
 dbSNP
15g.66481819C=CA2184097430MAP2K1c.567C= (p.Val189=)
c.633C= (p.Val211=)
c.486C= (p.Val162=)
c.569-5409C= (n.569-5409C=)
n.991C=
c.684C= (p.Val228=)
c.569-3175C= (n.569-3175C=)
c.489C= (p.Val163=)
c.105C= (p.Val35=)
c.555C= (p.Val185=)
15g.66481819C>GCA490858416MAP2K1c.567C>G (p.Val189=)
c.633C>G (p.Val211=)
c.486C>G (p.Val162=)
c.569-5409C>G (n.569-5409C>G)
n.991C>G
c.684C>G (p.Val228=)
c.569-3175C>G (n.569-3175C>G)
c.489C>G (p.Val163=)
c.105C>G (p.Val35=)
c.555C>G (p.Val185=)
 ClinVar dbSNP
15g.66481819C>TCA490858415MAP2K1c.567C>T (p.Val189=)
c.633C>T (p.Val211=)
c.486C>T (p.Val162=)
c.569-5409C>T (n.569-5409C>T)
n.991C>T
c.684C>T (p.Val228=)
c.569-3175C>T (n.569-3175C>T)
c.489C>T (p.Val163=)
c.105C>T (p.Val35=)
c.555C>T (p.Val185=)
 dbSNP COSMIC
15g.66481820A>CCA392936319MAP2K1c.568A>C (p.Ser190Arg)
c.634A>C (p.Ser212Arg)
c.487A>C (p.Ser163Arg)
c.569-5408A>C (n.569-5408A>C)
n.992A>C
c.685A>C (p.Ser229Arg)
c.569-3174A>C (n.569-3174A>C)
c.490A>C (p.Ser164Arg)
c.106A>C (p.Ser36Arg)
c.556A>C (p.Ser186Arg)
15g.66481820A>GCA392936321MAP2K1c.568A>G (p.Ser190Gly)
c.634A>G (p.Ser212Gly)
c.487A>G (p.Ser163Gly)
c.569-5408A>G (n.569-5408A>G)
n.992A>G
c.685A>G (p.Ser229Gly)
c.569-3174A>G (n.569-3174A>G)
c.490A>G (p.Ser164Gly)
c.106A>G (p.Ser36Gly)
c.556A>G (p.Ser186Gly)
 dbSNP
15g.66481820A>TCA392936322MAP2K1c.568A>T (p.Ser190Cys)
c.634A>T (p.Ser212Cys)
c.487A>T (p.Ser163Cys)
c.569-5408A>T (n.569-5408A>T)
n.992A>T
c.685A>T (p.Ser229Cys)
c.569-3174A>T (n.569-3174A>T)
c.490A>T (p.Ser164Cys)
c.106A>T (p.Ser36Cys)
c.556A>T (p.Ser186Cys)
 dbSNP
15g.66481821G>ACA392936324MAP2K1c.569G>A (p.Ser190Asn)
c.635G>A (p.Ser212Asn)
c.488G>A (p.Ser163Asn)
c.569-5407G>A (n.569-5407G>A)
n.993G>A
c.686G>A (p.Ser229Asn)
c.569-3173G>A (n.569-3173G>A)
c.491G>A (p.Ser164Asn)
c.107G>A (p.Ser36Asn)
c.557G>A (p.Ser186Asn)
 dbSNP COSMIC
15g.66481821G>CCA271671674MAP2K1c.569G>C (p.Ser190Thr)
c.635G>C (p.Ser212Thr)
c.488G>C (p.Ser163Thr)
c.569-5407G>C (n.569-5407G>C)
n.993G>C
c.686G>C (p.Ser229Thr)
c.569-3173G>C (n.569-3173G>C)
c.491G>C (p.Ser164Thr)
c.107G>C (p.Ser36Thr)
c.557G>C (p.Ser186Thr)
 ClinVar dbSNP
15g.66481821G=CA2184097432MAP2K1c.569G= (p.Ser190=)
c.635G= (p.Ser212=)
c.488G= (p.Ser163=)
c.569-5407G= (n.569-5407G=)
n.993G=
c.686G= (p.Ser229=)
c.569-3173G= (n.569-3173G=)
c.491G= (p.Ser164=)
c.107G= (p.Ser36=)
c.557G= (p.Ser186=)
15g.66481821G>TCA392936327MAP2K1c.569G>T (p.Ser190Ile)
c.635G>T (p.Ser212Ile)
c.488G>T (p.Ser163Ile)
c.569-5407G>T (n.569-5407G>T)
n.993G>T
c.686G>T (p.Ser229Ile)
c.569-3173G>T (n.569-3173G>T)
c.491G>T (p.Ser164Ile)
c.107G>T (p.Ser36Ile)
c.557G>T (p.Ser186Ile)
15g.66481822C>ACA392936329MAP2K1c.570C>A (p.Ser190Arg)
c.636C>A (p.Ser212Arg)
c.489C>A (p.Ser163Arg)
c.569-5406C>A (n.569-5406C>A)
n.994C>A
c.687C>A (p.Ser229Arg)
c.569-3172C>A (n.569-3172C>A)
c.492C>A (p.Ser164Arg)
c.108C>A (p.Ser36Arg)
c.558C>A (p.Ser186Arg)
 dbSNP
15g.66481822C=CA2184097434MAP2K1c.570C= (p.Ser190=)
c.636C= (p.Ser212=)
c.489C= (p.Ser163=)
c.569-5406C= (n.569-5406C=)
n.994C=
c.687C= (p.Ser229=)
c.569-3172C= (n.569-3172C=)
c.492C= (p.Ser164=)
c.108C= (p.Ser36=)
c.558C= (p.Ser186=)
15g.66481822C>GCA392936331MAP2K1c.570C>G (p.Ser190Arg)
c.636C>G (p.Ser212Arg)
c.489C>G (p.Ser163Arg)
c.569-5406C>G (n.569-5406C>G)
n.994C>G
c.687C>G (p.Ser229Arg)
c.569-3172C>G (n.569-3172C>G)
c.492C>G (p.Ser164Arg)
c.108C>G (p.Ser36Arg)
c.558C>G (p.Ser186Arg)
 dbSNP
15g.66481822C>TCA291989MAP2K1c.570C>T (p.Ser190=)
c.636C>T (p.Ser212=)
c.489C>T (p.Ser163=)
c.569-5406C>T (n.569-5406C>T)
n.994C>T
c.687C>T (p.Ser229=)
c.569-3172C>T (n.569-3172C>T)
c.492C>T (p.Ser164=)
c.108C>T (p.Ser36=)
c.558C>T (p.Ser186=)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
15g.66481823G>ACA392936338MAP2K1c.571G>A (p.Gly191Arg)
c.637G>A (p.Gly213Arg)
c.490G>A (p.Gly164Arg)
c.569-5405G>A (n.569-5405G>A)
n.995G>A
c.688G>A (p.Gly230Arg)
c.569-3171G>A (n.569-3171G>A)
c.493G>A (p.Gly165Arg)
c.109G>A (p.Gly37Arg)
c.559G>A (p.Gly187Arg)
 ClinVar dbSNP gnomAD v3 gnomAD v4
15g.66481823G>CCA392936335MAP2K1c.571G>C (p.Gly191Arg)
c.637G>C (p.Gly213Arg)
c.490G>C (p.Gly164Arg)
c.569-5405G>C (n.569-5405G>C)
n.995G>C
c.688G>C (p.Gly230Arg)
c.569-3171G>C (n.569-3171G>C)
c.493G>C (p.Gly165Arg)
c.109G>C (p.Gly37Arg)
c.559G>C (p.Gly187Arg)
 dbSNP
15g.66481823G=CA2184097436MAP2K1c.571G= (p.Gly191=)
c.637G= (p.Gly213=)
c.490G= (p.Gly164=)
c.569-5405G= (n.569-5405G=)
n.995G=
c.688G= (p.Gly230=)
c.569-3171G= (n.569-3171G=)
c.493G= (p.Gly165=)
c.109G= (p.Gly37=)
c.559G= (p.Gly187=)
15g.66481823G>TCA392936337MAP2K1c.571G>T (p.Gly191Trp)
c.637G>T (p.Gly213Trp)
c.490G>T (p.Gly164Trp)
c.569-5405G>T (n.569-5405G>T)
n.995G>T
c.688G>T (p.Gly230Trp)
c.569-3171G>T (n.569-3171G>T)
c.493G>T (p.Gly165Trp)
c.109G>T (p.Gly37Trp)
c.559G>T (p.Gly187Trp)
 dbSNP
15g.66481824G>ACA392936341MAP2K1c.572G>A (p.Gly191Glu)
c.638G>A (p.Gly213Glu)
c.491G>A (p.Gly164Glu)
c.569-5404G>A (n.569-5404G>A)
n.996G>A
c.689G>A (p.Gly230Glu)
c.569-3170G>A (n.569-3170G>A)
c.494G>A (p.Gly165Glu)
c.110G>A (p.Gly37Glu)
c.560G>A (p.Gly187Glu)
 dbSNP
15g.66481824G>CCA392936343MAP2K1c.572G>C (p.Gly191Ala)
c.638G>C (p.Gly213Ala)
c.491G>C (p.Gly164Ala)
c.569-5404G>C (n.569-5404G>C)
n.996G>C
c.689G>C (p.Gly230Ala)
c.569-3170G>C (n.569-3170G>C)
c.494G>C (p.Gly165Ala)
c.110G>C (p.Gly37Ala)
c.560G>C (p.Gly187Ala)
 dbSNP
15g.66481824G>TCA392936345MAP2K1c.572G>T (p.Gly191Val)
c.638G>T (p.Gly213Val)
c.491G>T (p.Gly164Val)
c.569-5404G>T (n.569-5404G>T)
n.996G>T
c.689G>T (p.Gly230Val)
c.569-3170G>T (n.569-3170G>T)
c.494G>T (p.Gly165Val)
c.110G>T (p.Gly37Val)
c.560G>T (p.Gly187Val)
 dbSNP
15g.66481825G>ACA271671679MAP2K1c.573G>A (p.Gly191=)
c.639G>A (p.Gly213=)
c.492G>A (p.Gly164=)
c.569-5403G>A (n.569-5403G>A)
n.997G>A
c.690G>A (p.Gly230=)
c.569-3169G>A (n.569-3169G>A)
c.495G>A (p.Gly165=)
c.111G>A (p.Gly37=)
c.561G>A (p.Gly187=)
 dbSNP
15g.66481825G>CCA490858417MAP2K1c.573G>C (p.Gly191=)
c.639G>C (p.Gly213=)
c.492G>C (p.Gly164=)
c.569-5403G>C (n.569-5403G>C)
n.997G>C
c.690G>C (p.Gly230=)
c.569-3169G>C (n.569-3169G>C)
c.495G>C (p.Gly165=)
c.111G>C (p.Gly37=)
c.561G>C (p.Gly187=)
 dbSNP
15g.66481825G=CA2184097439MAP2K1c.573G= (p.Gly191=)
c.639G= (p.Gly213=)
c.492G= (p.Gly164=)
c.569-5403G= (n.569-5403G=)
n.997G=
c.690G= (p.Gly230=)
c.569-3169G= (n.569-3169G=)
c.495G= (p.Gly165=)
c.111G= (p.Gly37=)
c.561G= (p.Gly187=)
15g.66481825G>TCA490858418MAP2K1c.573G>T (p.Gly191=)
c.639G>T (p.Gly213=)
c.492G>T (p.Gly164=)
c.569-5403G>T (n.569-5403G>T)
n.997G>T
c.690G>T (p.Gly230=)
c.569-3169G>T (n.569-3169G>T)
c.495G>T (p.Gly165=)
c.111G>T (p.Gly37=)
c.561G>T (p.Gly187=)
 dbSNP
15g.66481826C>ACA392936347MAP2K1c.574C>A (p.Gln192Lys)
c.640C>A (p.Gln214Lys)
c.493C>A (p.Gln165Lys)
c.569-5402C>A (n.569-5402C>A)
n.998C>A
c.691C>A (p.Gln231Lys)
c.569-3168C>A (n.569-3168C>A)
c.496C>A (p.Gln166Lys)
c.112C>A (p.Gln38Lys)
c.562C>A (p.Gln188Lys)
15g.66481826C>GCA392936349MAP2K1c.574C>G (p.Gln192Glu)
c.640C>G (p.Gln214Glu)
c.493C>G (p.Gln165Glu)
c.569-5402C>G (n.569-5402C>G)
n.998C>G
c.691C>G (p.Gln231Glu)
c.569-3168C>G (n.569-3168C>G)
c.496C>G (p.Gln166Glu)
c.112C>G (p.Gln38Glu)
c.562C>G (p.Gln188Glu)
 dbSNP
15g.66481826C>TCA392936351MAP2K1c.574C>T (p.Gln192Ter)
c.640C>T (p.Gln214Ter)
c.493C>T (p.Gln165Ter)
c.569-5402C>T (n.569-5402C>T)
n.998C>T
c.691C>T (p.Gln231Ter)
c.569-3168C>T (n.569-3168C>T)
c.496C>T (p.Gln166Ter)
c.112C>T (p.Gln38Ter)
c.562C>T (p.Gln188Ter)
 dbSNP gnomAD v4
15g.66481827A>CCA392936353MAP2K1c.575A>C (p.Gln192Pro)
c.641A>C (p.Gln214Pro)
c.494A>C (p.Gln165Pro)
c.569-5401A>C (n.569-5401A>C)
n.999A>C
c.692A>C (p.Gln231Pro)
c.569-3167A>C (n.569-3167A>C)
c.497A>C (p.Gln166Pro)
c.113A>C (p.Gln38Pro)
c.563A>C (p.Gln188Pro)
15g.66481827A>GCA392936355MAP2K1c.575A>G (p.Gln192Arg)
c.641A>G (p.Gln214Arg)
c.494A>G (p.Gln165Arg)
c.569-5401A>G (n.569-5401A>G)
n.999A>G
c.692A>G (p.Gln231Arg)
c.569-3167A>G (n.569-3167A>G)
c.497A>G (p.Gln166Arg)
c.113A>G (p.Gln38Arg)
c.563A>G (p.Gln188Arg)
 dbSNP
15g.66481827A>TCA392936357MAP2K1c.575A>T (p.Gln192Leu)
c.641A>T (p.Gln214Leu)
c.494A>T (p.Gln165Leu)
c.569-5401A>T (n.569-5401A>T)
n.999A>T
c.692A>T (p.Gln231Leu)
c.569-3167A>T (n.569-3167A>T)
c.497A>T (p.Gln166Leu)
c.113A>T (p.Gln38Leu)
c.563A>T (p.Gln188Leu)
 dbSNP
15g.66481828G>ACA271671685MAP2K1c.576G>A (p.Gln192=)
c.642G>A (p.Gln214=)
c.495G>A (p.Gln165=)
c.569-5400G>A (n.569-5400G>A)
n.1000G>A
c.693G>A (p.Gln231=)
c.569-3166G>A (n.569-3166G>A)
c.498G>A (p.Gln166=)
c.114G>A (p.Gln38=)
c.564G>A (p.Gln188=)
 dbSNP gnomAD v3 gnomAD v4
15g.66481828G>CCA392936358MAP2K1c.576G>C (p.Gln192His)
c.642G>C (p.Gln214His)
c.495G>C (p.Gln165His)
c.569-5400G>C (n.569-5400G>C)
n.1000G>C
c.693G>C (p.Gln231His)
c.569-3166G>C (n.569-3166G>C)
c.498G>C (p.Gln166His)
c.114G>C (p.Gln38His)
c.564G>C (p.Gln188His)
 dbSNP
15g.66481828G=CA2184097440MAP2K1c.576G= (p.Gln192=)
c.642G= (p.Gln214=)
c.495G= (p.Gln165=)
c.569-5400G= (n.569-5400G=)
n.1000G=
c.693G= (p.Gln231=)
c.569-3166G= (n.569-3166G=)
c.498G= (p.Gln166=)
c.114G= (p.Gln38=)
c.564G= (p.Gln188=)
15g.66481828G>TCA392936360MAP2K1c.576G>T (p.Gln192His)
c.642G>T (p.Gln214His)
c.495G>T (p.Gln165His)
c.569-5400G>T (n.569-5400G>T)
n.1000G>T
c.693G>T (p.Gln231His)
c.569-3166G>T (n.569-3166G>T)
c.498G>T (p.Gln166His)
c.114G>T (p.Gln38His)
c.564G>T (p.Gln188His)
15g.66481829C>ACA392936366MAP2K1c.577C>A (p.Leu193Ile)
c.643C>A (p.Leu215Ile)
c.496C>A (p.Leu166Ile)
c.569-5399C>A (n.569-5399C>A)
n.1001C>A
c.694C>A (p.Leu232Ile)
c.569-3165C>A (n.569-3165C>A)
c.499C>A (p.Leu167Ile)
c.115C>A (p.Leu39Ile)
c.565C>A (p.Leu189Ile)
 COSMIC
15g.66481829C>GCA392936364MAP2K1c.577C>G (p.Leu193Val)
c.643C>G (p.Leu215Val)
c.496C>G (p.Leu166Val)
c.569-5399C>G (n.569-5399C>G)
n.1001C>G
c.694C>G (p.Leu232Val)
c.569-3165C>G (n.569-3165C>G)
c.499C>G (p.Leu167Val)
c.115C>G (p.Leu39Val)
c.565C>G (p.Leu189Val)
 dbSNP
15g.66481829C>TCA392936362MAP2K1c.577C>T (p.Leu193Phe)
c.643C>T (p.Leu215Phe)
c.496C>T (p.Leu166Phe)
c.569-5399C>T (n.569-5399C>T)
n.1001C>T
c.694C>T (p.Leu232Phe)
c.569-3165C>T (n.569-3165C>T)
c.499C>T (p.Leu167Phe)
c.115C>T (p.Leu39Phe)
c.565C>T (p.Leu189Phe)
 COSMIC
15g.66481830T>ACA392936369MAP2K1c.578T>A (p.Leu193His)
c.644T>A (p.Leu215His)
c.497T>A (p.Leu166His)
c.569-5398T>A (n.569-5398T>A)
n.1002T>A
c.695T>A (p.Leu232His)
c.569-3164T>A (n.569-3164T>A)
c.500T>A (p.Leu167His)
c.116T>A (p.Leu39His)
c.566T>A (p.Leu189His)
 dbSNP
15g.66481830T>CCA16602654MAP2K1c.578T>C (p.Leu193Pro)
c.644T>C (p.Leu215Pro)
c.497T>C (p.Leu166Pro)
c.569-5398T>C (n.569-5398T>C)
n.1002T>C
c.695T>C (p.Leu232Pro)
c.569-3164T>C (n.569-3164T>C)
c.500T>C (p.Leu167Pro)
c.116T>C (p.Leu39Pro)
c.566T>C (p.Leu189Pro)
 ClinVar dbSNP
15g.66481830T>GCA392936370MAP2K1c.578T>G (p.Leu193Arg)
c.644T>G (p.Leu215Arg)
c.497T>G (p.Leu166Arg)
c.569-5398T>G (n.569-5398T>G)
n.1002T>G
c.695T>G (p.Leu232Arg)
c.569-3164T>G (n.569-3164T>G)
c.500T>G (p.Leu167Arg)
c.116T>G (p.Leu39Arg)
c.566T>G (p.Leu189Arg)
15g.66481830T=CA2184097442MAP2K1c.578T= (p.Leu193=)
c.644T= (p.Leu215=)
c.497T= (p.Leu166=)
c.569-5398T= (n.569-5398T=)
n.1002T=
c.695T= (p.Leu232=)
c.569-3164T= (n.569-3164T=)
c.500T= (p.Leu167=)
c.116T= (p.Leu39=)
c.566T= (p.Leu189=)
15g.66481831C>ACA490858419MAP2K1c.579C>A (p.Leu193=)
c.645C>A (p.Leu215=)
c.498C>A (p.Leu166=)
c.569-5397C>A (n.569-5397C>A)
n.1003C>A
c.696C>A (p.Leu232=)
c.569-3163C>A (n.569-3163C>A)
c.501C>A (p.Leu167=)
c.117C>A (p.Leu39=)
c.567C>A (p.Leu189=)
15g.66481831C>GCA490858421MAP2K1c.579C>G (p.Leu193=)
c.645C>G (p.Leu215=)
c.498C>G (p.Leu166=)
c.569-5397C>G (n.569-5397C>G)
n.1003C>G
c.696C>G (p.Leu232=)
c.569-3163C>G (n.569-3163C>G)
c.501C>G (p.Leu167=)
c.117C>G (p.Leu39=)
c.567C>G (p.Leu189=)
 ClinVar dbSNP gnomAD v3 gnomAD v4
15g.66481831C>TCA490858420MAP2K1c.579C>T (p.Leu193=)
c.645C>T (p.Leu215=)
c.498C>T (p.Leu166=)
c.569-5397C>T (n.569-5397C>T)
n.1003C>T
c.696C>T (p.Leu232=)
c.569-3163C>T (n.569-3163C>T)
c.501C>T (p.Leu167=)
c.117C>T (p.Leu39=)
c.567C>T (p.Leu189=)
 dbSNP
15g.66481832A>CCA392936372MAP2K1c.580A>C (p.Ile194Leu)
c.646A>C (p.Ile216Leu)
c.499A>C (p.Ile167Leu)
c.569-5396A>C (n.569-5396A>C)
n.1004A>C
c.697A>C (p.Ile233Leu)
c.569-3162A>C (n.569-3162A>C)
c.502A>C (p.Ile168Leu)
c.118A>C (p.Ile40Leu)
c.568A>C (p.Ile190Leu)
 dbSNP
15g.66481832A>GCA392936374MAP2K1c.580A>G (p.Ile194Val)
c.646A>G (p.Ile216Val)
c.499A>G (p.Ile167Val)
c.569-5396A>G (n.569-5396A>G)
n.1004A>G
c.697A>G (p.Ile233Val)
c.569-3162A>G (n.569-3162A>G)
c.502A>G (p.Ile168Val)
c.118A>G (p.Ile40Val)
c.568A>G (p.Ile190Val)
 dbSNP
15g.66481832A>TCA392936376MAP2K1c.580A>T (p.Ile194Phe)
c.646A>T (p.Ile216Phe)
c.499A>T (p.Ile167Phe)
c.569-5396A>T (n.569-5396A>T)
n.1004A>T
c.697A>T (p.Ile233Phe)
c.569-3162A>T (n.569-3162A>T)
c.502A>T (p.Ile168Phe)
c.118A>T (p.Ile40Phe)
c.568A>T (p.Ile190Phe)
 dbSNP
15g.66481833T>ACA392936378MAP2K1c.581T>A (p.Ile194Asn)
c.647T>A (p.Ile216Asn)
c.500T>A (p.Ile167Asn)
c.569-5395T>A (n.569-5395T>A)
n.1005T>A
c.698T>A (p.Ile233Asn)
c.569-3161T>A (n.569-3161T>A)
c.503T>A (p.Ile168Asn)
c.119T>A (p.Ile40Asn)
c.569T>A (p.Ile190Asn)
 dbSNP
15g.66481833T>CCA392936380MAP2K1c.581T>C (p.Ile194Thr)
c.647T>C (p.Ile216Thr)
c.500T>C (p.Ile167Thr)
c.569-5395T>C (n.569-5395T>C)
n.1005T>C
c.698T>C (p.Ile233Thr)
c.569-3161T>C (n.569-3161T>C)
c.503T>C (p.Ile168Thr)
c.119T>C (p.Ile40Thr)
c.569T>C (p.Ile190Thr)
 ClinVar dbSNP
15g.66481833T>GCA392936382MAP2K1c.581T>G (p.Ile194Ser)
c.647T>G (p.Ile216Ser)
c.500T>G (p.Ile167Ser)
c.569-5395T>G (n.569-5395T>G)
n.1005T>G
c.698T>G (p.Ile233Ser)
c.569-3161T>G (n.569-3161T>G)
c.503T>G (p.Ile168Ser)
c.119T>G (p.Ile40Ser)
c.569T>G (p.Ile190Ser)
 dbSNP
15g.66481834C>ACA490858422MAP2K1c.582C>A (p.Ile194=)
c.648C>A (p.Ile216=)
c.501C>A (p.Ile167=)
c.569-5394C>A (n.569-5394C>A)
n.1006C>A
c.699C>A (p.Ile233=)
c.569-3160C>A (n.569-3160C>A)
c.504C>A (p.Ile168=)
c.120C>A (p.Ile40=)
c.570C>A (p.Ile190=)
15g.66481834C=CA2184097445MAP2K1c.582C= (p.Ile194=)
c.648C= (p.Ile216=)
c.501C= (p.Ile167=)
c.569-5394C= (n.569-5394C=)
n.1006C=
c.699C= (p.Ile233=)
c.569-3160C= (n.569-3160C=)
c.504C= (p.Ile168=)
c.120C= (p.Ile40=)
c.570C= (p.Ile190=)
15g.66481834C>GCA392936383MAP2K1c.582C>G (p.Ile194Met)
c.648C>G (p.Ile216Met)
c.501C>G (p.Ile167Met)
c.569-5394C>G (n.569-5394C>G)
n.1006C>G
c.699C>G (p.Ile233Met)
c.569-3160C>G (n.569-3160C>G)
c.504C>G (p.Ile168Met)
c.120C>G (p.Ile40Met)
c.570C>G (p.Ile190Met)
 dbSNP
15g.66481834C>TCA134607MAP2K1c.582C>T (p.Ile194=)
c.648C>T (p.Ile216=)
c.501C>T (p.Ile167=)
c.569-5394C>T (n.569-5394C>T)
n.1006C>T
c.699C>T (p.Ile233=)
c.569-3160C>T (n.569-3160C>T)
c.504C>T (p.Ile168=)
c.120C>T (p.Ile40=)
c.570C>T (p.Ile190=)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
15g.66481835G>ACA7623996MAP2K1c.583G>A (p.Asp195Asn)
c.649G>A (p.Asp217Asn)
c.502G>A (p.Asp168Asn)
c.569-5393G>A (n.569-5393G>A)
n.1007G>A
c.700G>A (p.Asp234Asn)
c.569-3159G>A (n.569-3159G>A)
c.505G>A (p.Asp169Asn)
c.121G>A (p.Asp41Asn)
c.571G>A (p.Asp191Asn)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v4
15g.66481835G>CCA392936386MAP2K1c.583G>C (p.Asp195His)
c.649G>C (p.Asp217His)
c.502G>C (p.Asp168His)
c.569-5393G>C (n.569-5393G>C)
n.1007G>C
c.700G>C (p.Asp234His)
c.569-3159G>C (n.569-3159G>C)
c.505G>C (p.Asp169His)
c.121G>C (p.Asp41His)
c.571G>C (p.Asp191His)
 dbSNP
15g.66481835G=CA2184097448MAP2K1c.583G= (p.Asp195=)
c.649G= (p.Asp217=)
c.502G= (p.Asp168=)
c.569-5393G= (n.569-5393G=)
n.1007G=
c.700G= (p.Asp234=)
c.569-3159G= (n.569-3159G=)
c.505G= (p.Asp169=)
c.121G= (p.Asp41=)
c.571G= (p.Asp191=)
15g.66481835G>TCA392936387MAP2K1c.583G>T (p.Asp195Tyr)
c.649G>T (p.Asp217Tyr)
c.502G>T (p.Asp168Tyr)
c.569-5393G>T (n.569-5393G>T)
n.1007G>T
c.700G>T (p.Asp234Tyr)
c.569-3159G>T (n.569-3159G>T)
c.505G>T (p.Asp169Tyr)
c.121G>T (p.Asp41Tyr)
c.571G>T (p.Asp191Tyr)
15g.66481836A>CCA392936393MAP2K1c.584A>C (p.Asp195Ala)
c.650A>C (p.Asp217Ala)
c.503A>C (p.Asp168Ala)
c.569-5392A>C (n.569-5392A>C)
n.1008A>C
c.701A>C (p.Asp234Ala)
c.569-3158A>C (n.569-3158A>C)
c.506A>C (p.Asp169Ala)
c.122A>C (p.Asp41Ala)
c.572A>C (p.Asp191Ala)
 dbSNP
15g.66481836A>GCA392936390MAP2K1c.584A>G (p.Asp195Gly)
c.650A>G (p.Asp217Gly)
c.503A>G (p.Asp168Gly)
c.569-5392A>G (n.569-5392A>G)
n.1008A>G
c.701A>G (p.Asp234Gly)
c.569-3158A>G (n.569-3158A>G)
c.506A>G (p.Asp169Gly)
c.122A>G (p.Asp41Gly)
c.572A>G (p.Asp191Gly)
 dbSNP
15g.66481836A>TCA392936391MAP2K1c.584A>T (p.Asp195Val)
c.650A>T (p.Asp217Val)
c.503A>T (p.Asp168Val)
c.569-5392A>T (n.569-5392A>T)
n.1008A>T
c.701A>T (p.Asp234Val)
c.569-3158A>T (n.569-3158A>T)
c.506A>T (p.Asp169Val)
c.122A>T (p.Asp41Val)
c.572A>T (p.Asp191Val)
 dbSNP
15g.66481837C>ACA392936395MAP2K1c.585C>A (p.Asp195Glu)
c.651C>A (p.Asp217Glu)
c.504C>A (p.Asp168Glu)
c.569-5391C>A (n.569-5391C>A)
n.1009C>A
c.702C>A (p.Asp234Glu)
c.569-3157C>A (n.569-3157C>A)
c.507C>A (p.Asp169Glu)
c.123C>A (p.Asp41Glu)
c.573C>A (p.Asp191Glu)
15g.66481837C>GCA392936397MAP2K1c.585C>G (p.Asp195Glu)
c.651C>G (p.Asp217Glu)
c.504C>G (p.Asp168Glu)
c.569-5391C>G (n.569-5391C>G)
n.1009C>G
c.702C>G (p.Asp234Glu)
c.569-3157C>G (n.569-3157C>G)
c.507C>G (p.Asp169Glu)
c.123C>G (p.Asp41Glu)
c.573C>G (p.Asp191Glu)
 dbSNP
15g.66481837C>TCA490858423MAP2K1c.585C>T (p.Asp195=)
c.651C>T (p.Asp217=)
c.504C>T (p.Asp168=)
c.569-5391C>T (n.569-5391C>T)
n.1009C>T
c.702C>T (p.Asp234=)
c.569-3157C>T (n.569-3157C>T)
c.507C>T (p.Asp169=)
c.123C>T (p.Asp41=)
c.573C>T (p.Asp191=)
15g.66481838T>ACA392936400MAP2K1c.586T>A (p.Ser196Thr)
c.652T>A (p.Ser218Thr)
c.505T>A (p.Ser169Thr)
c.569-5390T>A (n.569-5390T>A)
n.1010T>A
c.703T>A (p.Ser235Thr)
c.569-3156T>A (n.569-3156T>A)
c.508T>A (p.Ser170Thr)
c.124T>A (p.Ser42Thr)
c.574T>A (p.Ser192Thr)
 dbSNP
15g.66481838T>CCA392936402MAP2K1c.586T>C (p.Ser196Pro)
c.652T>C (p.Ser218Pro)
c.505T>C (p.Ser169Pro)
c.569-5390T>C (n.569-5390T>C)
n.1010T>C
c.703T>C (p.Ser235Pro)
c.569-3156T>C (n.569-3156T>C)
c.508T>C (p.Ser170Pro)
c.124T>C (p.Ser42Pro)
c.574T>C (p.Ser192Pro)
 ClinVar dbSNP
15g.66481838T>GCA392936403MAP2K1c.586T>G (p.Ser196Ala)
c.652T>G (p.Ser218Ala)
c.505T>G (p.Ser169Ala)
c.569-5390T>G (n.569-5390T>G)
n.1010T>G
c.703T>G (p.Ser235Ala)
c.569-3156T>G (n.569-3156T>G)
c.508T>G (p.Ser170Ala)
c.124T>G (p.Ser42Ala)
c.574T>G (p.Ser192Ala)
15g.66481839C>ACA392936405MAP2K1c.587C>A (p.Ser196Tyr)
c.653C>A (p.Ser218Tyr)
c.506C>A (p.Ser169Tyr)
c.569-5389C>A (n.569-5389C>A)
n.1011C>A
c.704C>A (p.Ser235Tyr)
c.569-3155C>A (n.569-3155C>A)
c.509C>A (p.Ser170Tyr)
c.125C>A (p.Ser42Tyr)
c.575C>A (p.Ser192Tyr)
 dbSNP
15g.66481839C>GCA392936406MAP2K1c.587C>G (p.Ser196Cys)
c.653C>G (p.Ser218Cys)
c.506C>G (p.Ser169Cys)
c.569-5389C>G (n.569-5389C>G)
n.1011C>G
c.704C>G (p.Ser235Cys)
c.569-3155C>G (n.569-3155C>G)
c.509C>G (p.Ser170Cys)
c.125C>G (p.Ser42Cys)
c.575C>G (p.Ser192Cys)
 dbSNP
15g.66481839C>TCA392936408MAP2K1c.587C>T (p.Ser196Phe)
c.653C>T (p.Ser218Phe)
c.506C>T (p.Ser169Phe)
c.569-5389C>T (n.569-5389C>T)
n.1011C>T
c.704C>T (p.Ser235Phe)
c.569-3155C>T (n.569-3155C>T)
c.509C>T (p.Ser170Phe)
c.125C>T (p.Ser42Phe)
c.575C>T (p.Ser192Phe)
 dbSNP
15g.66481840C>ACA490858425MAP2K1c.588C>A (p.Ser196=)
c.654C>A (p.Ser218=)
c.507C>A (p.Ser169=)
c.569-5388C>A (n.569-5388C>A)
n.1012C>A
c.705C>A (p.Ser235=)
c.569-3154C>A (n.569-3154C>A)
c.510C>A (p.Ser170=)
c.126C>A (p.Ser42=)
c.576C>A (p.Ser192=)
 dbSNP gnomAD v4
15g.66481840C>GCA490858424MAP2K1c.588C>G (p.Ser196=)
c.654C>G (p.Ser218=)
c.507C>G (p.Ser169=)
c.569-5388C>G (n.569-5388C>G)
n.1012C>G
c.705C>G (p.Ser235=)
c.569-3154C>G (n.569-3154C>G)
c.510C>G (p.Ser170=)
c.126C>G (p.Ser42=)
c.576C>G (p.Ser192=)
 dbSNP
15g.66481840C>TCA490858426MAP2K1c.588C>T (p.Ser196=)
c.654C>T (p.Ser218=)
c.507C>T (p.Ser169=)
c.569-5388C>T (n.569-5388C>T)
n.1012C>T
c.705C>T (p.Ser235=)
c.569-3154C>T (n.569-3154C>T)
c.510C>T (p.Ser170=)
c.126C>T (p.Ser42=)
c.576C>T (p.Ser192=)
 dbSNP
15g.66481841A=CA2184097451MAP2K1c.589A= (p.Met197=)
c.655A= (p.Met219=)
c.508A= (p.Met170=)
c.569-5387A= (n.569-5387A=)
n.1013A=
c.706A= (p.Met236=)
c.569-3153A= (n.569-3153A=)
c.511A= (p.Met171=)
c.127A= (p.Met43=)
c.577A= (p.Met193=)
15g.66481841A>CCA392936410MAP2K1c.589A>C (p.Met197Leu)
c.655A>C (p.Met219Leu)
c.508A>C (p.Met170Leu)
c.569-5387A>C (n.569-5387A>C)
n.1013A>C
c.706A>C (p.Met236Leu)
c.569-3153A>C (n.569-3153A>C)
c.511A>C (p.Met171Leu)
c.127A>C (p.Met43Leu)
c.577A>C (p.Met193Leu)
 dbSNP
15g.66481841A>GCA392936412MAP2K1c.589A>G (p.Met197Val)
c.655A>G (p.Met219Val)
c.508A>G (p.Met170Val)
c.569-5387A>G (n.569-5387A>G)
n.1013A>G
c.706A>G (p.Met236Val)
c.569-3153A>G (n.569-3153A>G)
c.511A>G (p.Met171Val)
c.127A>G (p.Met43Val)
c.577A>G (p.Met193Val)
 dbSNP
15g.66481841A>TCA392936414MAP2K1c.589A>T (p.Met197Leu)
c.655A>T (p.Met219Leu)
c.508A>T (p.Met170Leu)
c.569-5387A>T (n.569-5387A>T)
n.1013A>T
c.706A>T (p.Met236Leu)
c.569-3153A>T (n.569-3153A>T)
c.511A>T (p.Met171Leu)
c.127A>T (p.Met43Leu)
c.577A>T (p.Met193Leu)
 dbSNP
15g.66481842T>ACA392936418MAP2K1c.590T>A (p.Met197Lys)
c.656T>A (p.Met219Lys)
c.509T>A (p.Met170Lys)
c.569-5386T>A (n.569-5386T>A)
n.1014T>A
c.707T>A (p.Met236Lys)
c.569-3152T>A (n.569-3152T>A)
c.512T>A (p.Met171Lys)
c.128T>A (p.Met43Lys)
c.578T>A (p.Met193Lys)
 dbSNP
15g.66481842T>CCA392936419MAP2K1c.590T>C (p.Met197Thr)
c.656T>C (p.Met219Thr)
c.509T>C (p.Met170Thr)
c.569-5386T>C (n.569-5386T>C)
n.1014T>C
c.707T>C (p.Met236Thr)
c.569-3152T>C (n.569-3152T>C)
c.512T>C (p.Met171Thr)
c.128T>C (p.Met43Thr)
c.578T>C (p.Met193Thr)
 dbSNP
15g.66481842T>GCA392936416MAP2K1c.590T>G (p.Met197Arg)
c.656T>G (p.Met219Arg)
c.509T>G (p.Met170Arg)
c.569-5386T>G (n.569-5386T>G)
n.1014T>G
c.707T>G (p.Met236Arg)
c.569-3152T>G (n.569-3152T>G)
c.512T>G (p.Met171Arg)
c.128T>G (p.Met43Arg)
c.578T>G (p.Met193Arg)
 dbSNP
15g.66481843G>ACA392936422MAP2K1c.591G>A (p.Met197Ile)
c.657G>A (p.Met219Ile)
c.510G>A (p.Met170Ile)
c.569-5385G>A (n.569-5385G>A)
n.1015G>A
c.708G>A (p.Met236Ile)
c.569-3151G>A (n.569-3151G>A)
c.513G>A (p.Met171Ile)
c.129G>A (p.Met43Ile)
c.579G>A (p.Met193Ile)
 dbSNP
15g.66481843G>CCA296119MAP2K1c.591G>C (p.Met197Ile)
c.657G>C (p.Met219Ile)
c.510G>C (p.Met170Ile)
c.569-5385G>C (n.569-5385G>C)
n.1015G>C
c.708G>C (p.Met236Ile)
c.569-3151G>C (n.569-3151G>C)
c.513G>C (p.Met171Ile)
c.129G>C (p.Met43Ile)
c.579G>C (p.Met193Ile)
 ClinVar dbSNP
15g.66481843G=CA2184097454MAP2K1c.591G= (p.Met197=)
c.657G= (p.Met219=)
c.510G= (p.Met170=)
c.569-5385G= (n.569-5385G=)
n.1015G=
c.708G= (p.Met236=)
c.569-3151G= (n.569-3151G=)
c.513G= (p.Met171=)
c.129G= (p.Met43=)
c.579G= (p.Met193=)
15g.66481843G>TCA392936424MAP2K1c.591G>T (p.Met197Ile)
c.657G>T (p.Met219Ile)
c.510G>T (p.Met170Ile)
c.569-5385G>T (n.569-5385G>T)
n.1015G>T
c.708G>T (p.Met236Ile)
c.569-3151G>T (n.569-3151G>T)
c.513G>T (p.Met171Ile)
c.129G>T (p.Met43Ile)
c.579G>T (p.Met193Ile)
15g.66481843_66481844delinsAACA2766290578MAP2K1c.591_592delinsAA (p.Met197_Ala198delinsIleThr)
c.657_658delinsAA (p.Met219_Ala220delinsIleThr)
c.510_511delinsAA (p.Met170_Ala171delinsIleThr)
c.569-5385_569-5384delinsAA (n.569-5385_569-5384delinsAA)
n.1015_1016delinsAA
c.708_709delinsAA (p.Met236_Ala237delinsIleThr)
c.569-3151_569-3150delinsAA (n.569-3151_569-3150delinsAA)
c.513_514delinsAA (p.Met171_Ala172delinsIleThr)
c.129_130delinsAA (p.Met43_Ala44delinsIleThr)
c.579_580delinsAA (p.Met193_Ala194delinsIleThr)
15g.66481844G>ACA392936425MAP2K1c.592G>A (p.Ala198Thr)
c.658G>A (p.Ala220Thr)
c.511G>A (p.Ala171Thr)
c.569-5384G>A (n.569-5384G>A)
n.1016G>A
c.709G>A (p.Ala237Thr)
c.569-3150G>A (n.569-3150G>A)
c.514G>A (p.Ala172Thr)
c.130G>A (p.Ala44Thr)
c.580G>A (p.Ala194Thr)
 dbSNP
15g.66481844G>CCA392936427MAP2K1c.592G>C (p.Ala198Pro)
c.658G>C (p.Ala220Pro)
c.511G>C (p.Ala171Pro)
c.569-5384G>C (n.569-5384G>C)
n.1016G>C
c.709G>C (p.Ala237Pro)
c.569-3150G>C (n.569-3150G>C)
c.514G>C (p.Ala172Pro)
c.130G>C (p.Ala44Pro)
c.580G>C (p.Ala194Pro)
 dbSNP
15g.66481844G>TCA392936429MAP2K1c.592G>T (p.Ala198Ser)
c.658G>T (p.Ala220Ser)
c.511G>T (p.Ala171Ser)
c.569-5384G>T (n.569-5384G>T)
n.1016G>T
c.709G>T (p.Ala237Ser)
c.569-3150G>T (n.569-3150G>T)
c.514G>T (p.Ala172Ser)
c.130G>T (p.Ala44Ser)
c.580G>T (p.Ala194Ser)
 dbSNP
15g.66481845C>ACA392936430MAP2K1c.593C>A (p.Ala198Asp)
c.659C>A (p.Ala220Asp)
c.512C>A (p.Ala171Asp)
c.569-5383C>A (n.569-5383C>A)
n.1017C>A
c.710C>A (p.Ala237Asp)
c.569-3149C>A (n.569-3149C>A)
c.515C>A (p.Ala172Asp)
c.131C>A (p.Ala44Asp)
c.581C>A (p.Ala194Asp)
 dbSNP
15g.66481845C>GCA392936431MAP2K1c.593C>G (p.Ala198Gly)
c.659C>G (p.Ala220Gly)
c.512C>G (p.Ala171Gly)
c.569-5383C>G (n.569-5383C>G)
n.1017C>G
c.710C>G (p.Ala237Gly)
c.569-3149C>G (n.569-3149C>G)
c.515C>G (p.Ala172Gly)
c.131C>G (p.Ala44Gly)
c.581C>G (p.Ala194Gly)
 dbSNP
15g.66481845C>TCA392936433MAP2K1c.593C>T (p.Ala198Val)
c.659C>T (p.Ala220Val)
c.512C>T (p.Ala171Val)
c.569-5383C>T (n.569-5383C>T)
n.1017C>T
c.710C>T (p.Ala237Val)
c.569-3149C>T (n.569-3149C>T)
c.515C>T (p.Ala172Val)
c.131C>T (p.Ala44Val)
c.581C>T (p.Ala194Val)
 dbSNP
15g.66481846C>ACA490858429MAP2K1c.594C>A (p.Ala198=)
c.660C>A (p.Ala220=)
c.513C>A (p.Ala171=)
c.569-5382C>A (n.569-5382C>A)
n.1018C>A
c.711C>A (p.Ala237=)
c.569-3148C>A (n.569-3148C>A)
c.516C>A (p.Ala172=)
c.132C>A (p.Ala44=)
c.582C>A (p.Ala194=)
 dbSNP
15g.66481846C>GCA490858427MAP2K1c.594C>G (p.Ala198=)
c.660C>G (p.Ala220=)
c.513C>G (p.Ala171=)
c.569-5382C>G (n.569-5382C>G)
n.1018C>G
c.711C>G (p.Ala237=)
c.569-3148C>G (n.569-3148C>G)
c.516C>G (p.Ala172=)
c.132C>G (p.Ala44=)
c.582C>G (p.Ala194=)
 dbSNP
15g.66481846C>TCA490858428MAP2K1c.594C>T (p.Ala198=)
c.660C>T (p.Ala220=)
c.513C>T (p.Ala171=)
c.569-5382C>T (n.569-5382C>T)
n.1018C>T
c.711C>T (p.Ala237=)
c.569-3148C>T (n.569-3148C>T)
c.516C>T (p.Ala172=)
c.132C>T (p.Ala44=)
c.582C>T (p.Ala194=)
 dbSNP
15g.66481847A>CCA392936435MAP2K1c.595A>C (p.Asn199His)
c.661A>C (p.Asn221His)
c.514A>C (p.Asn172His)
c.569-5381A>C (n.569-5381A>C)
n.1019A>C
c.712A>C (p.Asn238His)
c.569-3147A>C (n.569-3147A>C)
c.517A>C (p.Asn173His)
c.133A>C (p.Asn45His)
c.583A>C (p.Asn195His)
 dbSNP
15g.66481847A>GCA392936436MAP2K1c.595A>G (p.Asn199Asp)
c.661A>G (p.Asn221Asp)
c.514A>G (p.Asn172Asp)
c.569-5381A>G (n.569-5381A>G)
n.1019A>G
c.712A>G (p.Asn238Asp)
c.569-3147A>G (n.569-3147A>G)
c.517A>G (p.Asn173Asp)
c.133A>G (p.Asn45Asp)
c.583A>G (p.Asn195Asp)
15g.66481847A>TCA392936439MAP2K1c.595A>T (p.Asn199Tyr)
c.661A>T (p.Asn221Tyr)
c.514A>T (p.Asn172Tyr)
c.569-5381A>T (n.569-5381A>T)
n.1019A>T
c.712A>T (p.Asn238Tyr)
c.569-3147A>T (n.569-3147A>T)
c.517A>T (p.Asn173Tyr)
c.133A>T (p.Asn45Tyr)
c.583A>T (p.Asn195Tyr)
 dbSNP
15g.66481848A>CCA392936443MAP2K1c.596A>C (p.Asn199Thr)
c.662A>C (p.Asn221Thr)
c.515A>C (p.Asn172Thr)
c.569-5380A>C (n.569-5380A>C)
n.1020A>C
c.713A>C (p.Asn238Thr)
c.569-3146A>C (n.569-3146A>C)
c.518A>C (p.Asn173Thr)
c.134A>C (p.Asn45Thr)
c.584A>C (p.Asn195Thr)
 dbSNP gnomAD v4
15g.66481848A>GCA392936445MAP2K1c.596A>G (p.Asn199Ser)
c.662A>G (p.Asn221Ser)
c.515A>G (p.Asn172Ser)
c.569-5380A>G (n.569-5380A>G)
n.1020A>G
c.713A>G (p.Asn238Ser)
c.569-3146A>G (n.569-3146A>G)
c.518A>G (p.Asn173Ser)
c.134A>G (p.Asn45Ser)
c.584A>G (p.Asn195Ser)
 dbSNP
15g.66481848A>TCA392936441MAP2K1c.596A>T (p.Asn199Ile)
c.662A>T (p.Asn221Ile)
c.515A>T (p.Asn172Ile)
c.569-5380A>T (n.569-5380A>T)
n.1020A>T
c.713A>T (p.Asn238Ile)
c.569-3146A>T (n.569-3146A>T)
c.518A>T (p.Asn173Ile)
c.134A>T (p.Asn45Ile)
c.584A>T (p.Asn195Ile)
 dbSNP
15g.66481848_66481851delinsACTCCA2184097457MAP2K1c.596_599delinsACTC (p.Asn199=)
c.662_665delinsACTC (p.Asn221=)
c.515_518delinsACTC (p.Asn172=)
c.569-5380_569-5377delinsACTC (n.569-5380_569-5377delinsACTC)
n.1020_1023delinsACTC
c.713_716delinsACTC (p.Asn238=)
c.569-3146_569-3143delinsACTC (n.569-3146_569-3143delinsACTC)
c.518_521delinsACTC (p.Asn173=)
c.134_137delinsACTC (p.Asn45=)
c.584_587delinsACTC (p.Asn195=)
15g.66481849C>ACA392936447MAP2K1c.597C>A (p.Asn199Lys)
c.663C>A (p.Asn221Lys)
c.516C>A (p.Asn172Lys)
c.569-5379C>A (n.569-5379C>A)
n.1021C>A
c.714C>A (p.Asn238Lys)
c.569-3145C>A (n.569-3145C>A)
c.519C>A (p.Asn173Lys)
c.135C>A (p.Asn45Lys)
c.585C>A (p.Asn195Lys)
15g.66481849C=CA2184097458MAP2K1c.597C= (p.Asn199=)
c.663C= (p.Asn221=)
c.516C= (p.Asn172=)
c.569-5379C= (n.569-5379C=)
n.1021C=
c.714C= (p.Asn238=)
c.569-3145C= (n.569-3145C=)
c.519C= (p.Asn173=)
c.135C= (p.Asn45=)
c.585C= (p.Asn195=)
15g.66481849C>GCA392936449MAP2K1c.597C>G (p.Asn199Lys)
c.663C>G (p.Asn221Lys)
c.516C>G (p.Asn172Lys)
c.569-5379C>G (n.569-5379C>G)
n.1021C>G
c.714C>G (p.Asn238Lys)
c.569-3145C>G (n.569-3145C>G)
c.519C>G (p.Asn173Lys)
c.135C>G (p.Asn45Lys)
c.585C>G (p.Asn195Lys)
 dbSNP
15g.66481849C>TCA490858430MAP2K1c.597C>T (p.Asn199=)
c.663C>T (p.Asn221=)
c.516C>T (p.Asn172=)
c.569-5379C>T (n.569-5379C>T)
n.1021C>T
c.714C>T (p.Asn238=)
c.569-3145C>T (n.569-3145C>T)
c.519C>T (p.Asn173=)
c.135C>T (p.Asn45=)
c.585C>T (p.Asn195=)
 dbSNP gnomAD v2 gnomAD v4
15g.66481851_66481853delCA715033621MAP2K1c.599_601del (p.Ser200del)
c.665_667del (p.Ser222del)
c.518_520del (p.Ser173del)
c.569-5377_569-5375del (n.569-5377_569-5375del)
n.1023_1025del
c.716_718del (p.Ser239del)
c.569-3143_569-3141del (n.569-3143_569-3141del)
c.521_523del (p.Ser174del)
c.137_139del (p.Ser46del)
c.587_589del (p.Ser196del)
 dbSNP
15g.66481850T>ACA392936451MAP2K1c.598T>A (p.Ser200Thr)
c.664T>A (p.Ser222Thr)
c.517T>A (p.Ser173Thr)
c.569-5378T>A (n.569-5378T>A)
n.1022T>A
c.715T>A (p.Ser239Thr)
c.569-3144T>A (n.569-3144T>A)
c.520T>A (p.Ser174Thr)
c.136T>A (p.Ser46Thr)
c.586T>A (p.Ser196Thr)
 dbSNP
15g.66481850T>CCA392936452MAP2K1c.598T>C (p.Ser200Pro)
c.664T>C (p.Ser222Pro)
c.517T>C (p.Ser173Pro)
c.569-5378T>C (n.569-5378T>C)
n.1022T>C
c.715T>C (p.Ser239Pro)
c.569-3144T>C (n.569-3144T>C)
c.520T>C (p.Ser174Pro)
c.136T>C (p.Ser46Pro)
c.586T>C (p.Ser196Pro)
 dbSNP
15g.66481850T>GCA392936455MAP2K1c.598T>G (p.Ser200Ala)
c.664T>G (p.Ser222Ala)
c.517T>G (p.Ser173Ala)
c.569-5378T>G (n.569-5378T>G)
n.1022T>G
c.715T>G (p.Ser239Ala)
c.569-3144T>G (n.569-3144T>G)
c.520T>G (p.Ser174Ala)
c.136T>G (p.Ser46Ala)
c.586T>G (p.Ser196Ala)
15g.66481851C>ACA392936460MAP2K1c.599C>A (p.Ser200Tyr)
c.665C>A (p.Ser222Tyr)
c.518C>A (p.Ser173Tyr)
c.569-5377C>A (n.569-5377C>A)
n.1023C>A
c.716C>A (p.Ser239Tyr)
c.569-3143C>A (n.569-3143C>A)
c.521C>A (p.Ser174Tyr)
c.137C>A (p.Ser46Tyr)
c.587C>A (p.Ser196Tyr)
 ClinVar dbSNP
15g.66481851C>GCA392936457MAP2K1c.599C>G (p.Ser200Cys)
c.665C>G (p.Ser222Cys)
c.518C>G (p.Ser173Cys)
c.569-5377C>G (n.569-5377C>G)
n.1023C>G
c.716C>G (p.Ser239Cys)
c.569-3143C>G (n.569-3143C>G)
c.521C>G (p.Ser174Cys)
c.137C>G (p.Ser46Cys)
c.587C>G (p.Ser196Cys)
 dbSNP
15g.66481851C>TCA392936459MAP2K1c.599C>T (p.Ser200Phe)
c.665C>T (p.Ser222Phe)
c.518C>T (p.Ser173Phe)
c.569-5377C>T (n.569-5377C>T)
n.1023C>T
c.716C>T (p.Ser239Phe)
c.569-3143C>T (n.569-3143C>T)
c.521C>T (p.Ser174Phe)
c.137C>T (p.Ser46Phe)
c.587C>T (p.Ser196Phe)
 dbSNP
15g.66481852C>ACA490858431MAP2K1c.600C>A (p.Ser200=)
c.666C>A (p.Ser222=)
c.519C>A (p.Ser173=)
c.569-5376C>A (n.569-5376C>A)
n.1024C>A
c.717C>A (p.Ser239=)
c.569-3142C>A (n.569-3142C>A)
c.522C>A (p.Ser174=)
c.138C>A (p.Ser46=)
c.588C>A (p.Ser196=)
15g.66481852C>GCA490858432MAP2K1c.600C>G (p.Ser200=)
c.666C>G (p.Ser222=)
c.519C>G (p.Ser173=)
c.569-5376C>G (n.569-5376C>G)
n.1024C>G
c.717C>G (p.Ser239=)
c.569-3142C>G (n.569-3142C>G)
c.522C>G (p.Ser174=)
c.138C>G (p.Ser46=)
c.588C>G (p.Ser196=)
 dbSNP
15g.66481852C>TCA490858433MAP2K1c.600C>T (p.Ser200=)
c.666C>T (p.Ser222=)
c.519C>T (p.Ser173=)
c.569-5376C>T (n.569-5376C>T)
n.1024C>T
c.717C>T (p.Ser239=)
c.569-3142C>T (n.569-3142C>T)
c.522C>T (p.Ser174=)
c.138C>T (p.Ser46=)
c.588C>T (p.Ser196=)
 ClinVar dbSNP
15g.66481853T>ACA392936462MAP2K1c.601T>A (p.Phe201Ile)
c.667T>A (p.Phe223Ile)
c.520T>A (p.Phe174Ile)
c.569-5375T>A (n.569-5375T>A)
n.1025T>A
c.718T>A (p.Phe240Ile)
c.569-3141T>A (n.569-3141T>A)
c.523T>A (p.Phe175Ile)
c.139T>A (p.Phe47Ile)
c.589T>A (p.Phe197Ile)
 dbSNP
15g.66481853T>CCA392936463MAP2K1c.601T>C (p.Phe201Leu)
c.667T>C (p.Phe223Leu)
c.520T>C (p.Phe174Leu)
c.569-5375T>C (n.569-5375T>C)
n.1025T>C
c.718T>C (p.Phe240Leu)
c.569-3141T>C (n.569-3141T>C)
c.523T>C (p.Phe175Leu)
c.139T>C (p.Phe47Leu)
c.589T>C (p.Phe197Leu)
 dbSNP
15g.66481853T>GCA392936465MAP2K1c.601T>G (p.Phe201Val)
c.667T>G (p.Phe223Val)
c.520T>G (p.Phe174Val)
c.569-5375T>G (n.569-5375T>G)
n.1025T>G
c.718T>G (p.Phe240Val)
c.569-3141T>G (n.569-3141T>G)
c.523T>G (p.Phe175Val)
c.139T>G (p.Phe47Val)
c.589T>G (p.Phe197Val)
15g.66481854T>ACA392936467MAP2K1c.602T>A (p.Phe201Tyr)
c.668T>A (p.Phe223Tyr)
c.521T>A (p.Phe174Tyr)
c.569-5374T>A (n.569-5374T>A)
n.1026T>A
c.719T>A (p.Phe240Tyr)
c.569-3140T>A (n.569-3140T>A)
c.524T>A (p.Phe175Tyr)
c.140T>A (p.Phe47Tyr)
c.590T>A (p.Phe197Tyr)
 dbSNP
15g.66481854T>CCA392936469MAP2K1c.602T>C (p.Phe201Ser)
c.668T>C (p.Phe223Ser)
c.521T>C (p.Phe174Ser)
c.569-5374T>C (n.569-5374T>C)
n.1026T>C
c.719T>C (p.Phe240Ser)
c.569-3140T>C (n.569-3140T>C)
c.524T>C (p.Phe175Ser)
c.140T>C (p.Phe47Ser)
c.590T>C (p.Phe197Ser)
 dbSNP
15g.66481854T>GCA392936471MAP2K1c.602T>G (p.Phe201Cys)
c.668T>G (p.Phe223Cys)
c.521T>G (p.Phe174Cys)
c.569-5374T>G (n.569-5374T>G)
n.1026T>G
c.719T>G (p.Phe240Cys)
c.569-3140T>G (n.569-3140T>G)
c.524T>G (p.Phe175Cys)
c.140T>G (p.Phe47Cys)
c.590T>G (p.Phe197Cys)
15g.66481855C>ACA392936473MAP2K1c.603C>A (p.Phe201Leu)
c.669C>A (p.Phe223Leu)
c.522C>A (p.Phe174Leu)
c.569-5373C>A (n.569-5373C>A)
n.1027C>A
c.720C>A (p.Phe240Leu)
c.569-3139C>A (n.569-3139C>A)
c.525C>A (p.Phe175Leu)
c.141C>A (p.Phe47Leu)
c.591C>A (p.Phe197Leu)
15g.66481855C=CA2184097461MAP2K1c.603C= (p.Phe201=)
c.669C= (p.Phe223=)
c.522C= (p.Phe174=)
c.569-5373C= (n.569-5373C=)
n.1027C=
c.720C= (p.Phe240=)
c.569-3139C= (n.569-3139C=)
c.525C= (p.Phe175=)
c.141C= (p.Phe47=)
c.591C= (p.Phe197=)
15g.66481855C>GCA392936475MAP2K1c.603C>G (p.Phe201Leu)
c.669C>G (p.Phe223Leu)
c.522C>G (p.Phe174Leu)
c.569-5373C>G (n.569-5373C>G)
n.1027C>G
c.720C>G (p.Phe240Leu)
c.569-3139C>G (n.569-3139C>G)
c.525C>G (p.Phe175Leu)
c.141C>G (p.Phe47Leu)
c.591C>G (p.Phe197Leu)
 dbSNP
15g.66481855C>TCA490858434MAP2K1c.603C>T (p.Phe201=)
c.669C>T (p.Phe223=)
c.522C>T (p.Phe174=)
c.569-5373C>T (n.569-5373C>T)
n.1027C>T
c.720C>T (p.Phe240=)
c.569-3139C>T (n.569-3139C>T)
c.525C>T (p.Phe175=)
c.141C>T (p.Phe47=)
c.591C>T (p.Phe197=)
 ClinVar dbSNP gnomAD v3 gnomAD v4 COSMIC
15g.66481856G>ACA392936477MAP2K1c.604G>A (p.Val202Met)
c.670G>A (p.Val224Met)
c.523G>A (p.Val175Met)
c.569-5372G>A (n.569-5372G>A)
n.1028G>A
c.721G>A (p.Val241Met)
c.569-3138G>A (n.569-3138G>A)
c.526G>A (p.Val176Met)
c.142G>A (p.Val48Met)
c.592G>A (p.Val198Met)
 dbSNP COSMIC
15g.66481856G>CCA392936481MAP2K1c.604G>C (p.Val202Leu)
c.670G>C (p.Val224Leu)
c.523G>C (p.Val175Leu)
c.569-5372G>C (n.569-5372G>C)
n.1028G>C
c.721G>C (p.Val241Leu)
c.569-3138G>C (n.569-3138G>C)
c.526G>C (p.Val176Leu)
c.142G>C (p.Val48Leu)
c.592G>C (p.Val198Leu)
 dbSNP
15g.66481856G>TCA392936479MAP2K1c.604G>T (p.Val202Leu)
c.670G>T (p.Val224Leu)
c.523G>T (p.Val175Leu)
c.569-5372G>T (n.569-5372G>T)
n.1028G>T
c.721G>T (p.Val241Leu)
c.569-3138G>T (n.569-3138G>T)
c.526G>T (p.Val176Leu)
c.142G>T (p.Val48Leu)
c.592G>T (p.Val198Leu)
 dbSNP
15g.66481857T>ACA392936483MAP2K1c.605T>A (p.Val202Glu)
c.671T>A (p.Val224Glu)
c.524T>A (p.Val175Glu)
c.569-5371T>A (n.569-5371T>A)
n.1029T>A
c.722T>A (p.Val241Glu)
c.569-3137T>A (n.569-3137T>A)
c.527T>A (p.Val176Glu)
c.143T>A (p.Val48Glu)
c.593T>A (p.Val198Glu)
 dbSNP
15g.66481857T>CCA392936486MAP2K1c.605T>C (p.Val202Ala)
c.671T>C (p.Val224Ala)
c.524T>C (p.Val175Ala)
c.569-5371T>C (n.569-5371T>C)
n.1029T>C
c.722T>C (p.Val241Ala)
c.569-3137T>C (n.569-3137T>C)
c.527T>C (p.Val176Ala)
c.143T>C (p.Val48Ala)
c.593T>C (p.Val198Ala)
 dbSNP
15g.66481857T>GCA392936485MAP2K1c.605T>G (p.Val202Gly)
c.671T>G (p.Val224Gly)
c.524T>G (p.Val175Gly)
c.569-5371T>G (n.569-5371T>G)
n.1029T>G
c.722T>G (p.Val241Gly)
c.569-3137T>G (n.569-3137T>G)
c.527T>G (p.Val176Gly)
c.143T>G (p.Val48Gly)
c.593T>G (p.Val198Gly)
 dbSNP
15g.66481858G>ACA490858437MAP2K1c.606G>A (p.Val202=)
c.672G>A (p.Val224=)
c.525G>A (p.Val175=)
c.569-5370G>A (n.569-5370G>A)
n.1030G>A
c.723G>A (p.Val241=)
c.569-3136G>A (n.569-3136G>A)
c.528G>A (p.Val176=)
c.144G>A (p.Val48=)
c.594G>A (p.Val198=)
 ClinVar dbSNP
15g.66481858G>CCA490858435MAP2K1c.606G>C (p.Val202=)
c.672G>C (p.Val224=)
c.525G>C (p.Val175=)
c.569-5370G>C (n.569-5370G>C)
n.1030G>C
c.723G>C (p.Val241=)
c.569-3136G>C (n.569-3136G>C)
c.528G>C (p.Val176=)
c.144G>C (p.Val48=)
c.594G>C (p.Val198=)
 dbSNP
15g.66481858G>TCA490858436MAP2K1c.606G>T (p.Val202=)
c.672G>T (p.Val224=)
c.525G>T (p.Val175=)
c.569-5370G>T (n.569-5370G>T)
n.1030G>T
c.723G>T (p.Val241=)
c.569-3136G>T (n.569-3136G>T)
c.528G>T (p.Val176=)
c.144G>T (p.Val48=)
c.594G>T (p.Val198=)
15g.66481859G>ACA392936489MAP2K1c.607G>A (p.Gly203Ser)
c.673G>A (p.Gly225Ser)
c.526G>A (p.Gly176Ser)
c.569-5369G>A (n.569-5369G>A)
n.1031G>A
c.724G>A (p.Gly242Ser)
c.569-3135G>A (n.569-3135G>A)
c.529G>A (p.Gly177Ser)
c.145G>A (p.Gly49Ser)
c.595G>A (p.Gly199Ser)
 dbSNP
15g.66481859G>CCA392936492MAP2K1c.607G>C (p.Gly203Arg)
c.673G>C (p.Gly225Arg)
c.526G>C (p.Gly176Arg)
c.569-5369G>C (n.569-5369G>C)
n.1031G>C
c.724G>C (p.Gly242Arg)
c.569-3135G>C (n.569-3135G>C)
c.529G>C (p.Gly177Arg)
c.145G>C (p.Gly49Arg)
c.595G>C (p.Gly199Arg)
 dbSNP
15g.66481859G>TCA392936491MAP2K1c.607G>T (p.Gly203Cys)
c.673G>T (p.Gly225Cys)
c.526G>T (p.Gly176Cys)
c.569-5369G>T (n.569-5369G>T)
n.1031G>T
c.724G>T (p.Gly242Cys)
c.569-3135G>T (n.569-3135G>T)
c.529G>T (p.Gly177Cys)
c.145G>T (p.Gly49Cys)
c.595G>T (p.Gly199Cys)
 dbSNP
15g.66481860G>ACA392936494MAP2K1c.608G>A (p.Gly203Asp)
c.674G>A (p.Gly225Asp)
c.527G>A (p.Gly176Asp)
c.569-5368G>A (n.569-5368G>A)
n.1032G>A
c.725G>A (p.Gly242Asp)
c.569-3134G>A (n.569-3134G>A)
c.530G>A (p.Gly177Asp)
c.146G>A (p.Gly49Asp)
c.596G>A (p.Gly199Asp)
 dbSNP
15g.66481860G>CCA392936497MAP2K1c.608G>C (p.Gly203Ala)
c.674G>C (p.Gly225Ala)
c.527G>C (p.Gly176Ala)
c.569-5368G>C (n.569-5368G>C)
n.1032G>C
c.725G>C (p.Gly242Ala)
c.569-3134G>C (n.569-3134G>C)
c.530G>C (p.Gly177Ala)
c.146G>C (p.Gly49Ala)
c.596G>C (p.Gly199Ala)
 dbSNP
15g.66481860G>TCA392936496MAP2K1c.608G>T (p.Gly203Val)
c.674G>T (p.Gly225Val)
c.527G>T (p.Gly176Val)
c.569-5368G>T (n.569-5368G>T)
n.1032G>T
c.725G>T (p.Gly242Val)
c.569-3134G>T (n.569-3134G>T)
c.530G>T (p.Gly177Val)
c.146G>T (p.Gly49Val)
c.596G>T (p.Gly199Val)
 dbSNP
15g.66481861C>ACA490858439MAP2K1c.609C>A (p.Gly203=)
c.675C>A (p.Gly225=)
c.528C>A (p.Gly176=)
c.569-5367C>A (n.569-5367C>A)
n.1033C>A
c.726C>A (p.Gly242=)
c.569-3133C>A (n.569-3133C>A)
c.531C>A (p.Gly177=)
c.147C>A (p.Gly49=)
c.597C>A (p.Gly199=)
15g.66481861C>GCA490858440MAP2K1c.609C>G (p.Gly203=)
c.675C>G (p.Gly225=)
c.528C>G (p.Gly176=)
c.569-5367C>G (n.569-5367C>G)
n.1033C>G
c.726C>G (p.Gly242=)
c.569-3133C>G (n.569-3133C>G)
c.531C>G (p.Gly177=)
c.147C>G (p.Gly49=)
c.597C>G (p.Gly199=)
 dbSNP
15g.66481861C>TCA490858438MAP2K1c.609C>T (p.Gly203=)
c.675C>T (p.Gly225=)
c.528C>T (p.Gly176=)
c.569-5367C>T (n.569-5367C>T)
n.1033C>T
c.726C>T (p.Gly242=)
c.569-3133C>T (n.569-3133C>T)
c.531C>T (p.Gly177=)
c.147C>T (p.Gly49=)
c.597C>T (p.Gly199=)
 dbSNP
15g.66481862A>CCA392936500MAP2K1c.610A>C (p.Thr204Pro)
c.676A>C (p.Thr226Pro)
c.529A>C (p.Thr177Pro)
c.569-5366A>C (n.569-5366A>C)
n.1034A>C
c.727A>C (p.Thr243Pro)
c.569-3132A>C (n.569-3132A>C)
c.532A>C (p.Thr178Pro)
c.148A>C (p.Thr50Pro)
c.598A>C (p.Thr200Pro)
 dbSNP
15g.66481862A>GCA392936502MAP2K1c.610A>G (p.Thr204Ala)
c.676A>G (p.Thr226Ala)
c.529A>G (p.Thr177Ala)
c.569-5366A>G (n.569-5366A>G)
n.1034A>G
c.727A>G (p.Thr243Ala)
c.569-3132A>G (n.569-3132A>G)
c.532A>G (p.Thr178Ala)
c.148A>G (p.Thr50Ala)
c.598A>G (p.Thr200Ala)
15g.66481862A>TCA392936504MAP2K1c.610A>T (p.Thr204Ser)
c.676A>T (p.Thr226Ser)
c.529A>T (p.Thr177Ser)
c.569-5366A>T (n.569-5366A>T)
n.1034A>T
c.727A>T (p.Thr243Ser)
c.569-3132A>T (n.569-3132A>T)
c.532A>T (p.Thr178Ser)
c.148A>T (p.Thr50Ser)
c.598A>T (p.Thr200Ser)
 dbSNP
15g.66481863C>ACA392936506MAP2K1c.611C>A (p.Thr204Lys)
c.677C>A (p.Thr226Lys)
c.530C>A (p.Thr177Lys)
c.569-5365C>A (n.569-5365C>A)
n.1035C>A
c.728C>A (p.Thr243Lys)
c.569-3131C>A (n.569-3131C>A)
c.533C>A (p.Thr178Lys)
c.149C>A (p.Thr50Lys)
c.599C>A (p.Thr200Lys)
 dbSNP
15g.66481863C>GCA392936508MAP2K1c.611C>G (p.Thr204Arg)
c.677C>G (p.Thr226Arg)
c.530C>G (p.Thr177Arg)
c.569-5365C>G (n.569-5365C>G)
n.1035C>G
c.728C>G (p.Thr243Arg)
c.569-3131C>G (n.569-3131C>G)
c.533C>G (p.Thr178Arg)
c.149C>G (p.Thr50Arg)
c.599C>G (p.Thr200Arg)
 dbSNP
15g.66481863C>TCA392936510MAP2K1c.611C>T (p.Thr204Ile)
c.677C>T (p.Thr226Ile)
c.530C>T (p.Thr177Ile)
c.569-5365C>T (n.569-5365C>T)
n.1035C>T
c.728C>T (p.Thr243Ile)
c.569-3131C>T (n.569-3131C>T)
c.533C>T (p.Thr178Ile)
c.149C>T (p.Thr50Ile)
c.599C>T (p.Thr200Ile)
 dbSNP gnomAD v4
15g.66481864A>CCA490858442MAP2K1c.612A>C (p.Thr204=)
c.678A>C (p.Thr226=)
c.531A>C (p.Thr177=)
c.569-5364A>C (n.569-5364A>C)
n.1036A>C
c.729A>C (p.Thr243=)
c.569-3130A>C (n.569-3130A>C)
c.534A>C (p.Thr178=)
c.150A>C (p.Thr50=)
c.600A>C (p.Thr200=)
15g.66481864A>GCA490858441MAP2K1c.612A>G (p.Thr204=)
c.678A>G (p.Thr226=)
c.531A>G (p.Thr177=)
c.569-5364A>G (n.569-5364A>G)
n.1036A>G
c.729A>G (p.Thr243=)
c.569-3130A>G (n.569-3130A>G)
c.534A>G (p.Thr178=)
c.150A>G (p.Thr50=)
c.600A>G (p.Thr200=)
 dbSNP
15g.66481864A>TCA490858443MAP2K1c.612A>T (p.Thr204=)
c.678A>T (p.Thr226=)
c.531A>T (p.Thr177=)
c.569-5364A>T (n.569-5364A>T)
n.1036A>T
c.729A>T (p.Thr243=)
c.569-3130A>T (n.569-3130A>T)
c.534A>T (p.Thr178=)
c.150A>T (p.Thr50=)
c.600A>T (p.Thr200=)
15g.66481865A>CCA490858444MAP2K1c.613A>C (p.Arg205=)
c.679A>C (p.Arg227=)
c.532A>C (p.Arg178=)
c.569-5363A>C (n.569-5363A>C)
n.1037A>C
c.730A>C (p.Arg244=)
c.569-3129A>C (n.569-3129A>C)
c.535A>C (p.Arg179=)
c.151A>C (p.Arg51=)
c.601A>C (p.Arg201=)
15g.66481865A>GCA392936512MAP2K1c.613A>G (p.Arg205Gly)
c.679A>G (p.Arg227Gly)
c.532A>G (p.Arg178Gly)
c.569-5363A>G (n.569-5363A>G)
n.1037A>G
c.730A>G (p.Arg244Gly)
c.569-3129A>G (n.569-3129A>G)
c.535A>G (p.Arg179Gly)
c.151A>G (p.Arg51Gly)
c.601A>G (p.Arg201Gly)
 dbSNP gnomAD v4
15g.66481865A>TCA392936514MAP2K1c.613A>T (p.Arg205Trp)
c.679A>T (p.Arg227Trp)
c.532A>T (p.Arg178Trp)
c.569-5363A>T (n.569-5363A>T)
n.1037A>T
c.730A>T (p.Arg244Trp)
c.569-3129A>T (n.569-3129A>T)
c.535A>T (p.Arg179Trp)
c.151A>T (p.Arg51Trp)
c.601A>T (p.Arg201Trp)
 dbSNP
15g.66481866G>ACA392936517MAP2K1c.614G>A (p.Arg205Lys)
c.680G>A (p.Arg227Lys)
c.533G>A (p.Arg178Lys)
c.569-5362G>A (n.569-5362G>A)
n.1038G>A
c.731G>A (p.Arg244Lys)
c.569-3128G>A (n.569-3128G>A)
c.536G>A (p.Arg179Lys)
c.152G>A (p.Arg51Lys)
c.602G>A (p.Arg201Lys)
 dbSNP
15g.66481866G>CCA392936518MAP2K1c.614G>C (p.Arg205Thr)
c.680G>C (p.Arg227Thr)
c.533G>C (p.Arg178Thr)
c.569-5362G>C (n.569-5362G>C)
n.1038G>C
c.731G>C (p.Arg244Thr)
c.569-3128G>C (n.569-3128G>C)
c.536G>C (p.Arg179Thr)
c.152G>C (p.Arg51Thr)
c.602G>C (p.Arg201Thr)
 dbSNP
15g.66481866G>TCA392936521MAP2K1c.614G>T (p.Arg205Met)
c.680G>T (p.Arg227Met)
c.533G>T (p.Arg178Met)
c.569-5362G>T (n.569-5362G>T)
n.1038G>T
c.731G>T (p.Arg244Met)
c.569-3128G>T (n.569-3128G>T)
c.536G>T (p.Arg179Met)
c.152G>T (p.Arg51Met)
c.602G>T (p.Arg201Met)
 dbSNP
15g.66481867G>ACA490858445MAP2K1c.615G>A (p.Arg205=)
c.681G>A (p.Arg227=)
c.534G>A (p.Arg178=)
c.569-5361G>A (n.569-5361G>A)
n.1039G>A
c.732G>A (p.Arg244=)
c.569-3127G>A (n.569-3127G>A)
c.537G>A (p.Arg179=)
c.153G>A (p.Arg51=)
c.603G>A (p.Arg201=)
 dbSNP
15g.66481867G>CCA392936525MAP2K1c.615G>C (p.Arg205Ser)
c.681G>C (p.Arg227Ser)
c.534G>C (p.Arg178Ser)
c.569-5361G>C (n.569-5361G>C)
n.1039G>C
c.732G>C (p.Arg244Ser)
c.569-3127G>C (n.569-3127G>C)
c.537G>C (p.Arg179Ser)
c.153G>C (p.Arg51Ser)
c.603G>C (p.Arg201Ser)
 dbSNP
15g.66481867G>TCA392936523MAP2K1c.615G>T (p.Arg205Ser)
c.681G>T (p.Arg227Ser)
c.534G>T (p.Arg178Ser)
c.569-5361G>T (n.569-5361G>T)
n.1039G>T
c.732G>T (p.Arg244Ser)
c.569-3127G>T (n.569-3127G>T)
c.537G>T (p.Arg179Ser)
c.153G>T (p.Arg51Ser)
c.603G>T (p.Arg201Ser)
 ClinVar dbSNP
15g.66481868T>ACA392936527MAP2K1c.616T>A (p.Ser206Thr)
c.682T>A (p.Ser228Thr)
c.535T>A (p.Ser179Thr)
c.569-5360T>A (n.569-5360T>A)
n.1040T>A
c.733T>A (p.Ser245Thr)
c.569-3126T>A (n.569-3126T>A)
c.538T>A (p.Ser180Thr)
c.154T>A (p.Ser52Thr)
c.604T>A (p.Ser202Thr)
 dbSNP
15g.66481868T>CCA392936529MAP2K1c.616T>C (p.Ser206Pro)
c.682T>C (p.Ser228Pro)
c.535T>C (p.Ser179Pro)
c.569-5360T>C (n.569-5360T>C)
n.1040T>C
c.733T>C (p.Ser245Pro)
c.569-3126T>C (n.569-3126T>C)
c.538T>C (p.Ser180Pro)
c.154T>C (p.Ser52Pro)
c.604T>C (p.Ser202Pro)
 dbSNP
15g.66481868T>GCA392936531MAP2K1c.616T>G (p.Ser206Ala)
c.682T>G (p.Ser228Ala)
c.535T>G (p.Ser179Ala)
c.569-5360T>G (n.569-5360T>G)
n.1040T>G
c.733T>G (p.Ser245Ala)
c.569-3126T>G (n.569-3126T>G)
c.538T>G (p.Ser180Ala)
c.154T>G (p.Ser52Ala)
c.604T>G (p.Ser202Ala)
 dbSNP
15g.66481869C>ACA392936533MAP2K1c.617C>A (p.Ser206Tyr)
c.683C>A (p.Ser228Tyr)
c.536C>A (p.Ser179Tyr)
c.569-5359C>A (n.569-5359C>A)
n.1041C>A
c.734C>A (p.Ser245Tyr)
c.569-3125C>A (n.569-3125C>A)
c.539C>A (p.Ser180Tyr)
c.155C>A (p.Ser52Tyr)
c.605C>A (p.Ser202Tyr)
 dbSNP
15g.66481869C>GCA392936535MAP2K1c.617C>G (p.Ser206Cys)
c.683C>G (p.Ser228Cys)
c.536C>G (p.Ser179Cys)
c.569-5359C>G (n.569-5359C>G)
n.1041C>G
c.734C>G (p.Ser245Cys)
c.569-3125C>G (n.569-3125C>G)
c.539C>G (p.Ser180Cys)
c.155C>G (p.Ser52Cys)
c.605C>G (p.Ser202Cys)
 dbSNP
15g.66481869C>TCA392936537MAP2K1c.617C>T (p.Ser206Phe)
c.683C>T (p.Ser228Phe)
c.536C>T (p.Ser179Phe)
c.569-5359C>T (n.569-5359C>T)
n.1041C>T
c.734C>T (p.Ser245Phe)
c.569-3125C>T (n.569-3125C>T)
c.539C>T (p.Ser180Phe)
c.155C>T (p.Ser52Phe)
c.605C>T (p.Ser202Phe)
 dbSNP
15g.66481870C>ACA490858448MAP2K1c.618C>A (p.Ser206=)
c.684C>A (p.Ser228=)
c.537C>A (p.Ser179=)
c.569-5358C>A (n.569-5358C>A)
n.1042C>A
c.735C>A (p.Ser245=)
c.569-3124C>A (n.569-3124C>A)
c.540C>A (p.Ser180=)
c.156C>A (p.Ser52=)
c.606C>A (p.Ser202=)
 dbSNP
15g.66481870C>GCA490858446MAP2K1c.618C>G (p.Ser206=)
c.684C>G (p.Ser228=)
c.537C>G (p.Ser179=)
c.569-5358C>G (n.569-5358C>G)
n.1042C>G
c.735C>G (p.Ser245=)
c.569-3124C>G (n.569-3124C>G)
c.540C>G (p.Ser180=)
c.156C>G (p.Ser52=)
c.606C>G (p.Ser202=)
 dbSNP
15g.66481870C>TCA490858447MAP2K1c.618C>T (p.Ser206=)
c.684C>T (p.Ser228=)
c.537C>T (p.Ser179=)
c.569-5358C>T (n.569-5358C>T)
n.1042C>T
c.735C>T (p.Ser245=)
c.569-3124C>T (n.569-3124C>T)
c.540C>T (p.Ser180=)
c.156C>T (p.Ser52=)
c.606C>T (p.Ser202=)
15g.66481871T>ACA392936539MAP2K1c.619T>A (p.Tyr207Asn)
c.685T>A (p.Tyr229Asn)
c.538T>A (p.Tyr180Asn)
c.569-5357T>A (n.569-5357T>A)
n.1043T>A
c.736T>A (p.Tyr246Asn)
c.569-3123T>A (n.569-3123T>A)
c.541T>A (p.Tyr181Asn)
c.157T>A (p.Tyr53Asn)
c.607T>A (p.Tyr203Asn)
 dbSNP
15g.66481871T>CCA392936541MAP2K1c.619T>C (p.Tyr207His)
c.685T>C (p.Tyr229His)
c.538T>C (p.Tyr180His)
c.569-5357T>C (n.569-5357T>C)
n.1043T>C
c.736T>C (p.Tyr246His)
c.569-3123T>C (n.569-3123T>C)
c.541T>C (p.Tyr181His)
c.157T>C (p.Tyr53His)
c.607T>C (p.Tyr203His)
 dbSNP COSMIC
15g.66481871T>GCA392936543MAP2K1c.619T>G (p.Tyr207Asp)
c.685T>G (p.Tyr229Asp)
c.538T>G (p.Tyr180Asp)
c.569-5357T>G (n.569-5357T>G)
n.1043T>G
c.736T>G (p.Tyr246Asp)
c.569-3123T>G (n.569-3123T>G)
c.541T>G (p.Tyr181Asp)
c.157T>G (p.Tyr53Asp)
c.607T>G (p.Tyr203Asp)
15g.66481872A>CCA392936544MAP2K1c.620A>C (p.Tyr207Ser)
c.686A>C (p.Tyr229Ser)
c.539A>C (p.Tyr180Ser)
c.569-5356A>C (n.569-5356A>C)
n.1044A>C
c.737A>C (p.Tyr246Ser)
c.569-3122A>C (n.569-3122A>C)
c.542A>C (p.Tyr181Ser)
c.158A>C (p.Tyr53Ser)
c.608A>C (p.Tyr203Ser)
 dbSNP
15g.66481872A>GCA392936546MAP2K1c.620A>G (p.Tyr207Cys)
c.686A>G (p.Tyr229Cys)
c.539A>G (p.Tyr180Cys)
c.569-5356A>G (n.569-5356A>G)
n.1044A>G
c.737A>G (p.Tyr246Cys)
c.569-3122A>G (n.569-3122A>G)
c.542A>G (p.Tyr181Cys)
c.158A>G (p.Tyr53Cys)
c.608A>G (p.Tyr203Cys)
15g.66481872A>TCA392936547MAP2K1c.620A>T (p.Tyr207Phe)
c.686A>T (p.Tyr229Phe)
c.539A>T (p.Tyr180Phe)
c.569-5356A>T (n.569-5356A>T)
n.1044A>T
c.737A>T (p.Tyr246Phe)
c.569-3122A>T (n.569-3122A>T)
c.542A>T (p.Tyr181Phe)
c.158A>T (p.Tyr53Phe)
c.608A>T (p.Tyr203Phe)
 dbSNP
15g.66481873C>ACA392936551MAP2K1c.621C>A (p.Tyr207Ter)
c.687C>A (p.Tyr229Ter)
c.540C>A (p.Tyr180Ter)
c.569-5355C>A (n.569-5355C>A)
n.1045C>A
c.738C>A (p.Tyr246Ter)
c.569-3121C>A (n.569-3121C>A)
c.543C>A (p.Tyr181Ter)
c.159C>A (p.Tyr53Ter)
c.609C>A (p.Tyr203Ter)
 dbSNP
15g.66481873C=CA2184097463MAP2K1c.621C= (p.Tyr207=)
c.687C= (p.Tyr229=)
c.540C= (p.Tyr180=)
c.569-5355C= (n.569-5355C=)
n.1045C=
c.738C= (p.Tyr246=)
c.569-3121C= (n.569-3121C=)
c.543C= (p.Tyr181=)
c.159C= (p.Tyr53=)
c.609C= (p.Tyr203=)
15g.66481873C>GCA392936549MAP2K1c.621C>G (p.Tyr207Ter)
c.687C>G (p.Tyr229Ter)
c.540C>G (p.Tyr180Ter)
c.569-5355C>G (n.569-5355C>G)
n.1045C>G
c.738C>G (p.Tyr246Ter)
c.569-3121C>G (n.569-3121C>G)
c.543C>G (p.Tyr181Ter)
c.159C>G (p.Tyr53Ter)
c.609C>G (p.Tyr203Ter)
 dbSNP
15g.66481873C>TCA490858449MAP2K1c.621C>T (p.Tyr207=)
c.687C>T (p.Tyr229=)
c.540C>T (p.Tyr180=)
c.569-5355C>T (n.569-5355C>T)
n.1045C>T
c.738C>T (p.Tyr246=)
c.569-3121C>T (n.569-3121C>T)
c.543C>T (p.Tyr181=)
c.159C>T (p.Tyr53=)
c.609C>T (p.Tyr203=)
 dbSNP
15g.66481874A>CCA392936553MAP2K1c.622A>C (p.Met208Leu)
c.688A>C (p.Met230Leu)
c.541A>C (p.Met181Leu)
c.569-5354A>C (n.569-5354A>C)
n.1046A>C
c.739A>C (p.Met247Leu)
c.569-3120A>C (n.569-3120A>C)
c.544A>C (p.Met182Leu)
c.160A>C (p.Met54Leu)
c.610A>C (p.Met204Leu)
 gnomAD v4
15g.66481874A>GCA392936555MAP2K1c.622A>G (p.Met208Val)
c.688A>G (p.Met230Val)
c.541A>G (p.Met181Val)
c.569-5354A>G (n.569-5354A>G)
n.1046A>G
c.739A>G (p.Met247Val)
c.569-3120A>G (n.569-3120A>G)
c.544A>G (p.Met182Val)
c.160A>G (p.Met54Val)
c.610A>G (p.Met204Val)
15g.66481874A>TCA392936557MAP2K1c.622A>T (p.Met208Leu)
c.688A>T (p.Met230Leu)
c.541A>T (p.Met181Leu)
c.569-5354A>T (n.569-5354A>T)
n.1046A>T
c.739A>T (p.Met247Leu)
c.569-3120A>T (n.569-3120A>T)
c.544A>T (p.Met182Leu)
c.160A>T (p.Met54Leu)
c.610A>T (p.Met204Leu)
15g.66481875T>ACA392936559MAP2K1c.623T>A (p.Met208Lys)
c.689T>A (p.Met230Lys)
c.542T>A (p.Met181Lys)
c.569-5353T>A (n.569-5353T>A)
n.1047T>A
c.740T>A (p.Met247Lys)
c.569-3119T>A (n.569-3119T>A)
c.545T>A (p.Met182Lys)
c.161T>A (p.Met54Lys)
c.611T>A (p.Met204Lys)
 dbSNP
15g.66481875T>CCA392936560MAP2K1c.623T>C (p.Met208Thr)
c.689T>C (p.Met230Thr)
c.542T>C (p.Met181Thr)
c.569-5353T>C (n.569-5353T>C)
n.1047T>C
c.740T>C (p.Met247Thr)
c.569-3119T>C (n.569-3119T>C)
c.545T>C (p.Met182Thr)
c.161T>C (p.Met54Thr)
c.611T>C (p.Met204Thr)
15g.66481875T>GCA392936561MAP2K1c.623T>G (p.Met208Arg)
c.689T>G (p.Met230Arg)
c.542T>G (p.Met181Arg)
c.569-5353T>G (n.569-5353T>G)
n.1047T>G
c.740T>G (p.Met247Arg)
c.569-3119T>G (n.569-3119T>G)
c.545T>G (p.Met182Arg)
c.161T>G (p.Met54Arg)
c.611T>G (p.Met204Arg)
15g.66481876G>ACA392936562MAP2K1c.624G>A (p.Met208Ile)
c.690G>A (p.Met230Ile)
c.543G>A (p.Met181Ile)
c.569-5352G>A (n.569-5352G>A)
n.1048G>A
c.741G>A (p.Met247Ile)
c.569-3118G>A (n.569-3118G>A)
c.546G>A (p.Met182Ile)
c.162G>A (p.Met54Ile)
c.612G>A (p.Met204Ile)
 dbSNP
15g.66481876G>CCA392936563MAP2K1c.624G>C (p.Met208Ile)
c.690G>C (p.Met230Ile)
c.543G>C (p.Met181Ile)
c.569-5352G>C (n.569-5352G>C)
n.1048G>C
c.741G>C (p.Met247Ile)
c.569-3118G>C (n.569-3118G>C)
c.546G>C (p.Met182Ile)
c.162G>C (p.Met54Ile)
c.612G>C (p.Met204Ile)
 dbSNP
15g.66481876G>TCA392936564MAP2K1c.624G>T (p.Met208Ile)
c.690G>T (p.Met230Ile)
c.543G>T (p.Met181Ile)
c.569-5352G>T (n.569-5352G>T)
n.1048G>T
c.741G>T (p.Met247Ile)
c.569-3118G>T (n.569-3118G>T)
c.546G>T (p.Met182Ile)
c.162G>T (p.Met54Ile)
c.612G>T (p.Met204Ile)
15g.66481877T>ACA392936565MAP2K1c.625T>A (p.Ser209Thr)
c.691T>A (p.Ser231Thr)
c.544T>A (p.Ser182Thr)
c.569-5351T>A (n.569-5351T>A)
n.1049T>A
c.742T>A (p.Ser248Thr)
c.569-3117T>A (n.569-3117T>A)
c.547T>A (p.Ser183Thr)
c.163T>A (p.Ser55Thr)
c.613T>A (p.Ser205Thr)
 dbSNP
15g.66481877T>CCA392936566MAP2K1c.625T>C (p.Ser209Pro)
c.691T>C (p.Ser231Pro)
c.544T>C (p.Ser182Pro)
c.569-5351T>C (n.569-5351T>C)
n.1049T>C
c.742T>C (p.Ser248Pro)
c.569-3117T>C (n.569-3117T>C)
c.547T>C (p.Ser183Pro)
c.163T>C (p.Ser55Pro)
c.613T>C (p.Ser205Pro)
 dbSNP
15g.66481877T>GCA392936567MAP2K1c.625T>G (p.Ser209Ala)
c.691T>G (p.Ser231Ala)
c.544T>G (p.Ser182Ala)
c.569-5351T>G (n.569-5351T>G)
n.1049T>G
c.742T>G (p.Ser248Ala)
c.569-3117T>G (n.569-3117T>G)
c.547T>G (p.Ser183Ala)
c.163T>G (p.Ser55Ala)
c.613T>G (p.Ser205Ala)
 dbSNP
15g.66481878C>ACA392936570MAP2K1c.626C>A (p.Ser209Ter)
c.692C>A (p.Ser231Ter)
c.545C>A (p.Ser182Ter)
c.569-5350C>A (n.569-5350C>A)
n.1050C>A
c.743C>A (p.Ser248Ter)
c.569-3116C>A (n.569-3116C>A)
c.548C>A (p.Ser183Ter)
c.164C>A (p.Ser55Ter)
c.614C>A (p.Ser205Ter)
 dbSNP gnomAD v4
15g.66481878C=CA2184097465MAP2K1c.626C= (p.Ser209=)
c.692C= (p.Ser231=)
c.545C= (p.Ser182=)
c.569-5350C= (n.569-5350C=)
n.1050C=
c.743C= (p.Ser248=)
c.569-3116C= (n.569-3116C=)
c.548C= (p.Ser183=)
c.164C= (p.Ser55=)
c.614C= (p.Ser205=)
15g.66481878C>GCA392936569MAP2K1c.626C>G (p.Ser209Trp)
c.692C>G (p.Ser231Trp)
c.545C>G (p.Ser182Trp)
c.569-5350C>G (n.569-5350C>G)
n.1050C>G
c.743C>G (p.Ser248Trp)
c.569-3116C>G (n.569-3116C>G)
c.548C>G (p.Ser183Trp)
c.164C>G (p.Ser55Trp)
c.614C>G (p.Ser205Trp)
 ClinVar dbSNP
15g.66481878C>TCA392936568MAP2K1c.626C>T (p.Ser209Leu)
c.692C>T (p.Ser231Leu)
c.545C>T (p.Ser182Leu)
c.569-5350C>T (n.569-5350C>T)
n.1050C>T
c.743C>T (p.Ser248Leu)
c.569-3116C>T (n.569-3116C>T)
c.548C>T (p.Ser183Leu)
c.164C>T (p.Ser55Leu)
c.614C>T (p.Ser205Leu)
 ClinVar dbSNP gnomAD v2 gnomAD v4 COSMIC
15g.66481879G>ACA490858450MAP2K1c.627G>A (p.Ser209=)
c.693G>A (p.Ser231=)
c.546G>A (p.Ser182=)
c.569-5349G>A (n.569-5349G>A)
n.1051G>A
c.744G>A (p.Ser248=)
c.569-3115G>A (n.569-3115G>A)
c.549G>A (p.Ser183=)
c.165G>A (p.Ser55=)
c.615G>A (p.Ser205=)
 dbSNP gnomAD v2 gnomAD v4
15g.66481879G>CCA490858451MAP2K1c.627G>C (p.Ser209=)
c.693G>C (p.Ser231=)
c.546G>C (p.Ser182=)
c.569-5349G>C (n.569-5349G>C)
n.1051G>C
c.744G>C (p.Ser248=)
c.569-3115G>C (n.569-3115G>C)
c.549G>C (p.Ser183=)
c.165G>C (p.Ser55=)
c.615G>C (p.Ser205=)
15g.66481879G=CA2184097466MAP2K1c.627G= (p.Ser209=)
c.693G= (p.Ser231=)
c.546G= (p.Ser182=)
c.569-5349G= (n.569-5349G=)
n.1051G=
c.744G= (p.Ser248=)
c.569-3115G= (n.569-3115G=)
c.549G= (p.Ser183=)
c.165G= (p.Ser55=)
c.615G= (p.Ser205=)
15g.66481879G>TCA490858452MAP2K1c.627G>T (p.Ser209=)
c.693G>T (p.Ser231=)
c.546G>T (p.Ser182=)
c.569-5349G>T (n.569-5349G>T)
n.1051G>T
c.744G>T (p.Ser248=)
c.569-3115G>T (n.569-3115G>T)
c.549G>T (p.Ser183=)
c.165G>T (p.Ser55=)
c.615G>T (p.Ser205=)
15g.66481880G>ACA392936571MAP2K1c.627+1G>A (n.627+1G>A)
c.693+1G>A (n.693+1G>A)
c.546+1G>A (n.546+1G>A)
c.569-5348G>A (n.569-5348G>A)
n.1051+1G>A
c.744+1G>A (n.744+1G>A)
c.569-3114G>A (n.569-3114G>A)
c.549+1G>A (n.549+1G>A)
c.165+1G>A (n.165+1G>A)
c.615+1G>A (n.615+1G>A)
 dbSNP
15g.66481880G>CCA392936572MAP2K1c.627+1G>C (n.627+1G>C)
c.693+1G>C (n.693+1G>C)
c.546+1G>C (n.546+1G>C)
c.569-5348G>C (n.569-5348G>C)
n.1051+1G>C
c.744+1G>C (n.744+1G>C)
c.569-3114G>C (n.569-3114G>C)
c.549+1G>C (n.549+1G>C)
c.165+1G>C (n.165+1G>C)
c.615+1G>C (n.615+1G>C)
 dbSNP
15g.66481880G>TCA392936573MAP2K1c.627+1G>T (n.627+1G>T)
c.693+1G>T (n.693+1G>T)
c.546+1G>T (n.546+1G>T)
c.569-5348G>T (n.569-5348G>T)
n.1051+1G>T
c.744+1G>T (n.744+1G>T)
c.569-3114G>T (n.569-3114G>T)
c.549+1G>T (n.549+1G>T)
c.165+1G>T (n.165+1G>T)
c.615+1G>T (n.615+1G>T)
15g.66481881T>ACA392936574MAP2K1c.627+2T>A (n.627+2T>A)
c.693+2T>A (n.693+2T>A)
c.546+2T>A (n.546+2T>A)
c.569-5347T>A (n.569-5347T>A)
n.1051+2T>A
c.744+2T>A (n.744+2T>A)
c.569-3113T>A (n.569-3113T>A)
c.549+2T>A (n.549+2T>A)
c.165+2T>A (n.165+2T>A)
c.615+2T>A (n.615+2T>A)
 dbSNP
15g.66481881T>CCA392936575MAP2K1c.627+2T>C (n.627+2T>C)
c.693+2T>C (n.693+2T>C)
c.546+2T>C (n.546+2T>C)
c.569-5347T>C (n.569-5347T>C)
n.1051+2T>C
c.744+2T>C (n.744+2T>C)
c.569-3113T>C (n.569-3113T>C)
c.549+2T>C (n.549+2T>C)
c.165+2T>C (n.165+2T>C)
c.615+2T>C (n.615+2T>C)
15g.66481881T>GCA392936576MAP2K1c.627+2T>G (n.627+2T>G)
c.693+2T>G (n.693+2T>G)
c.546+2T>G (n.546+2T>G)
c.569-5347T>G (n.569-5347T>G)
n.1051+2T>G
c.744+2T>G (n.744+2T>G)
c.569-3113T>G (n.569-3113T>G)
c.549+2T>G (n.549+2T>G)
c.165+2T>G (n.165+2T>G)
c.615+2T>G (n.615+2T>G)
 dbSNP

Number of alleles fetched