Chr Mutation (hg38) CAid Gene Transcript Linkouts
5g.56881966C>ACA444399297MAP3K1c.2766C>A (p.Ala922=)
c.2388C>A (p.Ala796=)
c.2511C>A (p.Ala837=)
c.2487C>A (p.Ala829=)
c.2355C>A (p.Ala785=)
c.2277C>A (p.Ala759=)
n.2797C>A
5g.56881966C>GCA444399298MAP3K1c.2766C>G (p.Ala922=)
c.2388C>G (p.Ala796=)
c.2511C>G (p.Ala837=)
c.2487C>G (p.Ala829=)
c.2355C>G (p.Ala785=)
c.2277C>G (p.Ala759=)
n.2797C>G
5g.56881966C>TCA444399299MAP3K1c.2766C>T (p.Ala922=)
c.2388C>T (p.Ala796=)
c.2511C>T (p.Ala837=)
c.2487C>T (p.Ala829=)
c.2355C>T (p.Ala785=)
c.2277C>T (p.Ala759=)
n.2797C>T
5g.56881967A>CCA359786586MAP3K1c.2767A>C (p.Ser923Arg)
c.2389A>C (p.Ser797Arg)
c.2512A>C (p.Ser838Arg)
c.2488A>C (p.Ser830Arg)
c.2356A>C (p.Ser786Arg)
c.2278A>C (p.Ser760Arg)
n.2798A>C
5g.56881967A>GCA359786588MAP3K1c.2767A>G (p.Ser923Gly)
c.2389A>G (p.Ser797Gly)
c.2512A>G (p.Ser838Gly)
c.2488A>G (p.Ser830Gly)
c.2356A>G (p.Ser786Gly)
c.2278A>G (p.Ser760Gly)
n.2798A>G
5g.56881967A>TCA359786587MAP3K1c.2767A>T (p.Ser923Cys)
c.2389A>T (p.Ser797Cys)
c.2512A>T (p.Ser838Cys)
c.2488A>T (p.Ser830Cys)
c.2356A>T (p.Ser786Cys)
c.2278A>T (p.Ser760Cys)
n.2798A>T
 gnomAD v4
5g.56881968G>ACA359786589MAP3K1c.2768G>A (p.Ser923Asn)
c.2390G>A (p.Ser797Asn)
c.2513G>A (p.Ser838Asn)
c.2489G>A (p.Ser830Asn)
c.2357G>A (p.Ser786Asn)
c.2279G>A (p.Ser760Asn)
n.2799G>A
 dbSNP
5g.56881968G>CCA3273055MAP3K1c.2768G>C (p.Ser923Thr)
c.2390G>C (p.Ser797Thr)
c.2513G>C (p.Ser838Thr)
c.2489G>C (p.Ser830Thr)
c.2357G>C (p.Ser786Thr)
c.2279G>C (p.Ser760Thr)
n.2799G>C
 dbSNP ExAC gnomAD v2 gnomAD v4
5g.56881968G=CA1548139374MAP3K1c.2768G= (p.Ser923=)
c.2390G= (p.Ser797=)
c.2513G= (p.Ser838=)
c.2489G= (p.Ser830=)
c.2357G= (p.Ser786=)
c.2279G= (p.Ser760=)
n.2799G=
5g.56881968G>TCA359786590MAP3K1c.2768G>T (p.Ser923Ile)
c.2390G>T (p.Ser797Ile)
c.2513G>T (p.Ser838Ile)
c.2489G>T (p.Ser830Ile)
c.2357G>T (p.Ser786Ile)
c.2279G>T (p.Ser760Ile)
n.2799G>T
5g.56881969T>ACA359786591MAP3K1c.2769T>A (p.Ser923Arg)
c.2391T>A (p.Ser797Arg)
c.2514T>A (p.Ser838Arg)
c.2490T>A (p.Ser830Arg)
c.2358T>A (p.Ser786Arg)
c.2280T>A (p.Ser760Arg)
n.2800T>A
5g.56881969T>CCA444399300MAP3K1c.2769T>C (p.Ser923=)
c.2391T>C (p.Ser797=)
c.2514T>C (p.Ser838=)
c.2490T>C (p.Ser830=)
c.2358T>C (p.Ser786=)
c.2280T>C (p.Ser760=)
n.2800T>C
5g.56881969T>GCA359786592MAP3K1c.2769T>G (p.Ser923Arg)
c.2391T>G (p.Ser797Arg)
c.2514T>G (p.Ser838Arg)
c.2490T>G (p.Ser830Arg)
c.2358T>G (p.Ser786Arg)
c.2280T>G (p.Ser760Arg)
n.2800T>G
 dbSNP gnomAD v3 gnomAD v4
5g.56881969T=CA1548139375MAP3K1c.2769T= (p.Ser923=)
c.2391T= (p.Ser797=)
c.2514T= (p.Ser838=)
c.2490T= (p.Ser830=)
c.2358T= (p.Ser786=)
c.2280T= (p.Ser760=)
n.2800T=
5g.56881970T>ACA359786593MAP3K1c.2770T>A (p.Ser924Thr)
c.2392T>A (p.Ser798Thr)
c.2515T>A (p.Ser839Thr)
c.2491T>A (p.Ser831Thr)
c.2359T>A (p.Ser787Thr)
c.2281T>A (p.Ser761Thr)
n.2801T>A
 dbSNP
5g.56881970T>CCA359786594MAP3K1c.2770T>C (p.Ser924Pro)
c.2392T>C (p.Ser798Pro)
c.2515T>C (p.Ser839Pro)
c.2491T>C (p.Ser831Pro)
c.2359T>C (p.Ser787Pro)
c.2281T>C (p.Ser761Pro)
n.2801T>C
 gnomAD v4
5g.56881970T>GCA359786595MAP3K1c.2770T>G (p.Ser924Ala)
c.2392T>G (p.Ser798Ala)
c.2515T>G (p.Ser839Ala)
c.2491T>G (p.Ser831Ala)
c.2359T>G (p.Ser787Ala)
c.2281T>G (p.Ser761Ala)
n.2801T>G
5g.56881971C>ACA359786596MAP3K1c.2771C>A (p.Ser924Ter)
c.2393C>A (p.Ser798Ter)
c.2516C>A (p.Ser839Ter)
c.2492C>A (p.Ser831Ter)
c.2360C>A (p.Ser787Ter)
c.2282C>A (p.Ser761Ter)
n.2802C>A
5g.56881971C>GCA359786597MAP3K1c.2771C>G (p.Ser924Ter)
c.2393C>G (p.Ser798Ter)
c.2516C>G (p.Ser839Ter)
c.2492C>G (p.Ser831Ter)
c.2360C>G (p.Ser787Ter)
c.2282C>G (p.Ser761Ter)
n.2802C>G
5g.56881971C>TCA359786598MAP3K1c.2771C>T (p.Ser924Leu)
c.2393C>T (p.Ser798Leu)
c.2516C>T (p.Ser839Leu)
c.2492C>T (p.Ser831Leu)
c.2360C>T (p.Ser787Leu)
c.2282C>T (p.Ser761Leu)
n.2802C>T
5g.56881972A=CA1548139376MAP3K1c.2772A= (p.Ser924=)
c.2394A= (p.Ser798=)
c.2517A= (p.Ser839=)
c.2493A= (p.Ser831=)
c.2361A= (p.Ser787=)
c.2283A= (p.Ser761=)
n.2803A=
5g.56881972A>CCA444399304MAP3K1c.2772A>C (p.Ser924=)
c.2394A>C (p.Ser798=)
c.2517A>C (p.Ser839=)
c.2493A>C (p.Ser831=)
c.2361A>C (p.Ser787=)
c.2283A>C (p.Ser761=)
n.2803A>C
5g.56881972A>GCA3273056MAP3K1c.2772A>G (p.Ser924=)
c.2394A>G (p.Ser798=)
c.2517A>G (p.Ser839=)
c.2493A>G (p.Ser831=)
c.2361A>G (p.Ser787=)
c.2283A>G (p.Ser761=)
n.2803A>G
 dbSNP ExAC gnomAD v2 gnomAD v4
5g.56881972A>TCA444399305MAP3K1c.2772A>T (p.Ser924=)
c.2394A>T (p.Ser798=)
c.2517A>T (p.Ser839=)
c.2493A>T (p.Ser831=)
c.2361A>T (p.Ser787=)
c.2283A>T (p.Ser761=)
n.2803A>T
5g.56881973G>ACA359786599MAP3K1c.2773G>A (p.Glu925Lys)
c.2395G>A (p.Glu799Lys)
c.2518G>A (p.Glu840Lys)
c.2494G>A (p.Glu832Lys)
c.2362G>A (p.Glu788Lys)
c.2284G>A (p.Glu762Lys)
n.2804G>A
 dbSNP gnomAD v2 gnomAD v4
5g.56881973G>CCA359786601MAP3K1c.2773G>C (p.Glu925Gln)
c.2395G>C (p.Glu799Gln)
c.2518G>C (p.Glu840Gln)
c.2494G>C (p.Glu832Gln)
c.2362G>C (p.Glu788Gln)
c.2284G>C (p.Glu762Gln)
n.2804G>C
5g.56881973G=CA1548139377MAP3K1c.2773G= (p.Glu925=)
c.2395G= (p.Glu799=)
c.2518G= (p.Glu840=)
c.2494G= (p.Glu832=)
c.2362G= (p.Glu788=)
c.2284G= (p.Glu762=)
n.2804G=
5g.56881973G>TCA359786600MAP3K1c.2773G>T (p.Glu925Ter)
c.2395G>T (p.Glu799Ter)
c.2518G>T (p.Glu840Ter)
c.2494G>T (p.Glu832Ter)
c.2362G>T (p.Glu788Ter)
c.2284G>T (p.Glu762Ter)
n.2804G>T
5g.56881974A=CA1548139378MAP3K1c.2774A= (p.Glu925=)
c.2396A= (p.Glu799=)
c.2519A= (p.Glu840=)
c.2495A= (p.Glu832=)
c.2363A= (p.Glu788=)
c.2285A= (p.Glu762=)
n.2805A=
5g.56881974A>CCA359786602MAP3K1c.2774A>C (p.Glu925Ala)
c.2396A>C (p.Glu799Ala)
c.2519A>C (p.Glu840Ala)
c.2495A>C (p.Glu832Ala)
c.2363A>C (p.Glu788Ala)
c.2285A>C (p.Glu762Ala)
n.2805A>C
5g.56881974A>GCA359786603MAP3K1c.2774A>G (p.Glu925Gly)
c.2396A>G (p.Glu799Gly)
c.2519A>G (p.Glu840Gly)
c.2495A>G (p.Glu832Gly)
c.2363A>G (p.Glu788Gly)
c.2285A>G (p.Glu762Gly)
n.2805A>G
 dbSNP gnomAD v3 gnomAD v4
5g.56881974A>TCA359786604MAP3K1c.2774A>T (p.Glu925Val)
c.2396A>T (p.Glu799Val)
c.2519A>T (p.Glu840Val)
c.2495A>T (p.Glu832Val)
c.2363A>T (p.Glu788Val)
c.2285A>T (p.Glu762Val)
n.2805A>T
5g.56881975G>ACA119079474MAP3K1c.2775G>A (p.Glu925=)
c.2397G>A (p.Glu799=)
c.2520G>A (p.Glu840=)
c.2496G>A (p.Glu832=)
c.2364G>A (p.Glu788=)
c.2286G>A (p.Glu762=)
n.2806G>A
 dbSNP
5g.56881975G>CCA359786605MAP3K1c.2775G>C (p.Glu925Asp)
c.2397G>C (p.Glu799Asp)
c.2520G>C (p.Glu840Asp)
c.2496G>C (p.Glu832Asp)
c.2364G>C (p.Glu788Asp)
c.2286G>C (p.Glu762Asp)
n.2806G>C
5g.56881975G=CA1548139379MAP3K1c.2775G= (p.Glu925=)
c.2397G= (p.Glu799=)
c.2520G= (p.Glu840=)
c.2496G= (p.Glu832=)
c.2364G= (p.Glu788=)
c.2286G= (p.Glu762=)
n.2806G=
5g.56881975G>TCA359786606MAP3K1c.2775G>T (p.Glu925Asp)
c.2397G>T (p.Glu799Asp)
c.2520G>T (p.Glu840Asp)
c.2496G>T (p.Glu832Asp)
c.2364G>T (p.Glu788Asp)
c.2286G>T (p.Glu762Asp)
n.2806G>T
5g.56881976delCA645557014MAP3K1c.2776del (p.Asp926ThrfsTer11)
c.2398del (p.Asp800ThrfsTer11)
c.2521del (p.Asp841ThrfsTer11)
c.2497del (p.Asp833ThrfsTer11)
c.2365del (p.Asp789ThrfsTer11)
c.2287del (p.Asp763ThrfsTer11)
n.2807del
 COSMIC
5g.56881976G>ACA119079499MAP3K1c.2776G>A (p.Asp926Asn)
c.2398G>A (p.Asp800Asn)
c.2521G>A (p.Asp841Asn)
c.2497G>A (p.Asp833Asn)
c.2365G>A (p.Asp789Asn)
c.2287G>A (p.Asp763Asn)
n.2807G>A
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56881976G>CCA359786607MAP3K1c.2776G>C (p.Asp926His)
c.2398G>C (p.Asp800His)
c.2521G>C (p.Asp841His)
c.2497G>C (p.Asp833His)
c.2365G>C (p.Asp789His)
c.2287G>C (p.Asp763His)
n.2807G>C
5g.56881976G=CA1548139380MAP3K1c.2776G= (p.Asp926=)
c.2398G= (p.Asp800=)
c.2521G= (p.Asp841=)
c.2497G= (p.Asp833=)
c.2365G= (p.Asp789=)
c.2287G= (p.Asp763=)
n.2807G=
5g.56881976G>TCA359786608MAP3K1c.2776G>T (p.Asp926Tyr)
c.2398G>T (p.Asp800Tyr)
c.2521G>T (p.Asp841Tyr)
c.2497G>T (p.Asp833Tyr)
c.2365G>T (p.Asp789Tyr)
c.2287G>T (p.Asp763Tyr)
n.2807G>T
5g.56881977A=CA1548139381MAP3K1c.2777A= (p.Asp926=)
c.2399A= (p.Asp800=)
c.2522A= (p.Asp841=)
c.2498A= (p.Asp833=)
c.2366A= (p.Asp789=)
c.2288A= (p.Asp763=)
n.2808A=
5g.56881977A>CCA359786609MAP3K1c.2777A>C (p.Asp926Ala)
c.2399A>C (p.Asp800Ala)
c.2522A>C (p.Asp841Ala)
c.2498A>C (p.Asp833Ala)
c.2366A>C (p.Asp789Ala)
c.2288A>C (p.Asp763Ala)
n.2808A>C
5g.56881977A>GCA359786610MAP3K1c.2777A>G (p.Asp926Gly)
c.2399A>G (p.Asp800Gly)
c.2522A>G (p.Asp841Gly)
c.2498A>G (p.Asp833Gly)
c.2366A>G (p.Asp789Gly)
c.2288A>G (p.Asp763Gly)
n.2808A>G
5g.56881977A>TCA359786611MAP3K1c.2777A>T (p.Asp926Val)
c.2399A>T (p.Asp800Val)
c.2522A>T (p.Asp841Val)
c.2498A>T (p.Asp833Val)
c.2366A>T (p.Asp789Val)
c.2288A>T (p.Asp763Val)
n.2808A>T
 dbSNP gnomAD v2 gnomAD v4
5g.56881978C>ACA359786612MAP3K1c.2778C>A (p.Asp926Glu)
c.2400C>A (p.Asp800Glu)
c.2523C>A (p.Asp841Glu)
c.2499C>A (p.Asp833Glu)
c.2367C>A (p.Asp789Glu)
c.2289C>A (p.Asp763Glu)
n.2809C>A
5g.56881978C=CA1548139382MAP3K1c.2778C= (p.Asp926=)
c.2400C= (p.Asp800=)
c.2523C= (p.Asp841=)
c.2499C= (p.Asp833=)
c.2367C= (p.Asp789=)
c.2289C= (p.Asp763=)
n.2809C=
5g.56881978C>GCA359786613MAP3K1c.2778C>G (p.Asp926Glu)
c.2400C>G (p.Asp800Glu)
c.2523C>G (p.Asp841Glu)
c.2499C>G (p.Asp833Glu)
c.2367C>G (p.Asp789Glu)
c.2289C>G (p.Asp763Glu)
n.2809C>G
5g.56881978C>TCA444399307MAP3K1c.2778C>T (p.Asp926=)
c.2400C>T (p.Asp800=)
c.2523C>T (p.Asp841=)
c.2499C>T (p.Asp833=)
c.2367C>T (p.Asp789=)
c.2289C>T (p.Asp763=)
n.2809C>T
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56881979A=CA1548139383MAP3K1c.2779A= (p.Ile927=)
c.2401A= (p.Ile801=)
c.2524A= (p.Ile842=)
c.2500A= (p.Ile834=)
c.2368A= (p.Ile790=)
c.2290A= (p.Ile764=)
n.2810A=
5g.56881979A>CCA359786614MAP3K1c.2779A>C (p.Ile927Leu)
c.2401A>C (p.Ile801Leu)
c.2524A>C (p.Ile842Leu)
c.2500A>C (p.Ile834Leu)
c.2368A>C (p.Ile790Leu)
c.2290A>C (p.Ile764Leu)
n.2810A>C
5g.56881979A>GCA3273057MAP3K1c.2779A>G (p.Ile927Val)
c.2401A>G (p.Ile801Val)
c.2524A>G (p.Ile842Val)
c.2500A>G (p.Ile834Val)
c.2368A>G (p.Ile790Val)
c.2290A>G (p.Ile764Val)
n.2810A>G
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56881979A>TCA359786615MAP3K1c.2779A>T (p.Ile927Phe)
c.2401A>T (p.Ile801Phe)
c.2524A>T (p.Ile842Phe)
c.2500A>T (p.Ile834Phe)
c.2368A>T (p.Ile790Phe)
c.2290A>T (p.Ile764Phe)
n.2810A>T
5g.56881980T>ACA359786616MAP3K1c.2780T>A (p.Ile927Asn)
c.2402T>A (p.Ile801Asn)
c.2525T>A (p.Ile842Asn)
c.2501T>A (p.Ile834Asn)
c.2369T>A (p.Ile790Asn)
c.2291T>A (p.Ile764Asn)
n.2811T>A
5g.56881980T>CCA359786617MAP3K1c.2780T>C (p.Ile927Thr)
c.2402T>C (p.Ile801Thr)
c.2525T>C (p.Ile842Thr)
c.2501T>C (p.Ile834Thr)
c.2369T>C (p.Ile790Thr)
c.2291T>C (p.Ile764Thr)
n.2811T>C
5g.56881980T>GCA359786618MAP3K1c.2780T>G (p.Ile927Ser)
c.2402T>G (p.Ile801Ser)
c.2525T>G (p.Ile842Ser)
c.2501T>G (p.Ile834Ser)
c.2369T>G (p.Ile790Ser)
c.2291T>G (p.Ile764Ser)
n.2811T>G
5g.56881982delCA2673909976MAP3K1c.2782del (p.Ser928LeufsTer9)
c.2404del (p.Ser802LeufsTer9)
c.2527del (p.Ser843LeufsTer9)
c.2503del (p.Ser835LeufsTer9)
c.2371del (p.Ser791LeufsTer9)
c.2293del (p.Ser765LeufsTer9)
n.2813del
 gnomAD v4
5g.56881980_56881983delinsTTTCCA1548139384MAP3K1c.2780_2783delinsTTTC (p.Ile927=)
c.2402_2405delinsTTTC (p.Ile801=)
c.2525_2528delinsTTTC (p.Ile842=)
c.2501_2504delinsTTTC (p.Ile834=)
c.2369_2372delinsTTTC (p.Ile790=)
c.2291_2294delinsTTTC (p.Ile764=)
n.2811_2814delinsTTTC
5g.56881981T>ACA444399310MAP3K1c.2781T>A (p.Ile927=)
c.2403T>A (p.Ile801=)
c.2526T>A (p.Ile842=)
c.2502T>A (p.Ile834=)
c.2370T>A (p.Ile790=)
c.2292T>A (p.Ile764=)
n.2812T>A
5g.56881981T>CCA444399309MAP3K1c.2781T>C (p.Ile927=)
c.2403T>C (p.Ile801=)
c.2526T>C (p.Ile842=)
c.2502T>C (p.Ile834=)
c.2370T>C (p.Ile790=)
c.2292T>C (p.Ile764=)
n.2812T>C
5g.56881981T>GCA359786619MAP3K1c.2781T>G (p.Ile927Met)
c.2403T>G (p.Ile801Met)
c.2526T>G (p.Ile842Met)
c.2502T>G (p.Ile834Met)
c.2370T>G (p.Ile790Met)
c.2292T>G (p.Ile764Met)
n.2812T>G
5g.56881982_56881984delCA916082712MAP3K1c.2782_2784del (p.Ser928del)
c.2404_2406del (p.Ser802del)
c.2527_2529del (p.Ser843del)
c.2503_2505del (p.Ser835del)
c.2371_2373del (p.Ser791del)
c.2293_2295del (p.Ser765del)
n.2813_2815del
 ClinVar dbSNP
5g.56881982T>ACA359786620MAP3K1c.2782T>A (p.Ser928Thr)
c.2404T>A (p.Ser802Thr)
c.2527T>A (p.Ser843Thr)
c.2503T>A (p.Ser835Thr)
c.2371T>A (p.Ser791Thr)
c.2293T>A (p.Ser765Thr)
n.2813T>A
5g.56881982T>CCA359786621MAP3K1c.2782T>C (p.Ser928Pro)
c.2404T>C (p.Ser802Pro)
c.2527T>C (p.Ser843Pro)
c.2503T>C (p.Ser835Pro)
c.2371T>C (p.Ser791Pro)
c.2293T>C (p.Ser765Pro)
n.2813T>C
5g.56881982T>GCA359786622MAP3K1c.2782T>G (p.Ser928Ala)
c.2404T>G (p.Ser802Ala)
c.2527T>G (p.Ser843Ala)
c.2503T>G (p.Ser835Ala)
c.2371T>G (p.Ser791Ala)
c.2293T>G (p.Ser765Ala)
n.2813T>G
5g.56881983C>ACA359786623MAP3K1c.2783C>A (p.Ser928Tyr)
c.2405C>A (p.Ser802Tyr)
c.2528C>A (p.Ser843Tyr)
c.2504C>A (p.Ser835Tyr)
c.2372C>A (p.Ser791Tyr)
c.2294C>A (p.Ser765Tyr)
n.2814C>A
 dbSNP
5g.56881983C>GCA359786624MAP3K1c.2783C>G (p.Ser928Cys)
c.2405C>G (p.Ser802Cys)
c.2528C>G (p.Ser843Cys)
c.2504C>G (p.Ser835Cys)
c.2372C>G (p.Ser791Cys)
c.2294C>G (p.Ser765Cys)
n.2814C>G
5g.56881983C>TCA359786625MAP3K1c.2783C>T (p.Ser928Phe)
c.2405C>T (p.Ser802Phe)
c.2528C>T (p.Ser843Phe)
c.2504C>T (p.Ser835Phe)
c.2372C>T (p.Ser791Phe)
c.2294C>T (p.Ser765Phe)
n.2814C>T
 dbSNP
5g.56881984T>ACA444399312MAP3K1c.2784T>A (p.Ser928=)
c.2406T>A (p.Ser802=)
c.2529T>A (p.Ser843=)
c.2505T>A (p.Ser835=)
c.2373T>A (p.Ser791=)
c.2295T>A (p.Ser765=)
n.2815T>A
5g.56881984T>CCA444399316MAP3K1c.2784T>C (p.Ser928=)
c.2406T>C (p.Ser802=)
c.2529T>C (p.Ser843=)
c.2505T>C (p.Ser835=)
c.2373T>C (p.Ser791=)
c.2295T>C (p.Ser765=)
n.2815T>C
5g.56881984T>GCA444399314MAP3K1c.2784T>G (p.Ser928=)
c.2406T>G (p.Ser802=)
c.2529T>G (p.Ser843=)
c.2505T>G (p.Ser835=)
c.2373T>G (p.Ser791=)
c.2295T>G (p.Ser765=)
n.2815T>G
 dbSNP
5g.56881984_56881985insTACA645557015MAP3K1c.2784_2785insTA (p.Glu929Ter)
c.2406_2407insTA (p.Glu803Ter)
c.2529_2530insTA (p.Glu844Ter)
c.2505_2506insTA (p.Glu836Ter)
c.2373_2374insTA (p.Glu792Ter)
c.2295_2296insTA (p.Glu766Ter)
n.2815_2816insTA
 COSMIC
5g.56881985G>ACA359786628MAP3K1c.2785G>A (p.Glu929Lys)
c.2407G>A (p.Glu803Lys)
c.2530G>A (p.Glu844Lys)
c.2506G>A (p.Glu836Lys)
c.2374G>A (p.Glu792Lys)
c.2296G>A (p.Glu766Lys)
n.2816G>A
 dbSNP
5g.56881985G>CCA359786626MAP3K1c.2785G>C (p.Glu929Gln)
c.2407G>C (p.Glu803Gln)
c.2530G>C (p.Glu844Gln)
c.2506G>C (p.Glu836Gln)
c.2374G>C (p.Glu792Gln)
c.2296G>C (p.Glu766Gln)
n.2816G>C
5g.56881985G>TCA359786627MAP3K1c.2785G>T (p.Glu929Ter)
c.2407G>T (p.Glu803Ter)
c.2530G>T (p.Glu844Ter)
c.2506G>T (p.Glu836Ter)
c.2374G>T (p.Glu792Ter)
c.2296G>T (p.Glu766Ter)
n.2816G>T
5g.56881986A>CCA359786629MAP3K1c.2786A>C (p.Glu929Ala)
c.2408A>C (p.Glu803Ala)
c.2531A>C (p.Glu844Ala)
c.2507A>C (p.Glu836Ala)
c.2375A>C (p.Glu792Ala)
c.2297A>C (p.Glu766Ala)
n.2817A>C
5g.56881986A>GCA359786631MAP3K1c.2786A>G (p.Glu929Gly)
c.2408A>G (p.Glu803Gly)
c.2531A>G (p.Glu844Gly)
c.2507A>G (p.Glu836Gly)
c.2375A>G (p.Glu792Gly)
c.2297A>G (p.Glu766Gly)
n.2817A>G
5g.56881986A>TCA359786630MAP3K1c.2786A>T (p.Glu929Val)
c.2408A>T (p.Glu803Val)
c.2531A>T (p.Glu844Val)
c.2507A>T (p.Glu836Val)
c.2375A>T (p.Glu792Val)
c.2297A>T (p.Glu766Val)
n.2817A>T
5g.56881987G>ACA444399317MAP3K1c.2787G>A (p.Glu929=)
c.2409G>A (p.Glu803=)
c.2532G>A (p.Glu844=)
c.2508G>A (p.Glu836=)
c.2376G>A (p.Glu792=)
c.2298G>A (p.Glu766=)
n.2818G>A
 COSMIC
5g.56881987G>CCA359786632MAP3K1c.2787G>C (p.Glu929Asp)
c.2409G>C (p.Glu803Asp)
c.2532G>C (p.Glu844Asp)
c.2508G>C (p.Glu836Asp)
c.2376G>C (p.Glu792Asp)
c.2298G>C (p.Glu766Asp)
n.2818G>C
 gnomAD v3 gnomAD v4
5g.56881987G>TCA359786633MAP3K1c.2787G>T (p.Glu929Asp)
c.2409G>T (p.Glu803Asp)
c.2532G>T (p.Glu844Asp)
c.2508G>T (p.Glu836Asp)
c.2376G>T (p.Glu792Asp)
c.2298G>T (p.Glu766Asp)
n.2818G>T
5g.56881988A>CCA444399318MAP3K1c.2788A>C (p.Arg930=)
c.2410A>C (p.Arg804=)
c.2533A>C (p.Arg845=)
c.2509A>C (p.Arg837=)
c.2377A>C (p.Arg793=)
c.2299A>C (p.Arg767=)
n.2819A>C
5g.56881988A>GCA359786634MAP3K1c.2788A>G (p.Arg930Gly)
c.2410A>G (p.Arg804Gly)
c.2533A>G (p.Arg845Gly)
c.2509A>G (p.Arg837Gly)
c.2377A>G (p.Arg793Gly)
c.2299A>G (p.Arg767Gly)
n.2819A>G
5g.56881988A>TCA359786635MAP3K1c.2788A>T (p.Arg930Ter)
c.2410A>T (p.Arg804Ter)
c.2533A>T (p.Arg845Ter)
c.2509A>T (p.Arg837Ter)
c.2377A>T (p.Arg793Ter)
c.2299A>T (p.Arg767Ter)
n.2819A>T
5g.56881989G>ACA359786636MAP3K1c.2789G>A (p.Arg930Lys)
c.2411G>A (p.Arg804Lys)
c.2534G>A (p.Arg845Lys)
c.2510G>A (p.Arg837Lys)
c.2378G>A (p.Arg793Lys)
c.2300G>A (p.Arg767Lys)
n.2820G>A
5g.56881989G>CCA359786637MAP3K1c.2789G>C (p.Arg930Thr)
c.2411G>C (p.Arg804Thr)
c.2534G>C (p.Arg845Thr)
c.2510G>C (p.Arg837Thr)
c.2378G>C (p.Arg793Thr)
c.2300G>C (p.Arg767Thr)
n.2820G>C
 gnomAD v4
5g.56881989G>TCA359786638MAP3K1c.2789G>T (p.Arg930Ile)
c.2411G>T (p.Arg804Ile)
c.2534G>T (p.Arg845Ile)
c.2510G>T (p.Arg837Ile)
c.2378G>T (p.Arg793Ile)
c.2300G>T (p.Arg767Ile)
n.2820G>T
 gnomAD v4
5g.56881990A>CCA359786639MAP3K1c.2790A>C (p.Arg930Ser)
c.2412A>C (p.Arg804Ser)
c.2535A>C (p.Arg845Ser)
c.2511A>C (p.Arg837Ser)
c.2379A>C (p.Arg793Ser)
c.2301A>C (p.Arg767Ser)
n.2821A>C
5g.56881990A>GCA444399321MAP3K1c.2790A>G (p.Arg930=)
c.2412A>G (p.Arg804=)
c.2535A>G (p.Arg845=)
c.2511A>G (p.Arg837=)
c.2379A>G (p.Arg793=)
c.2301A>G (p.Arg767=)
n.2821A>G
5g.56881990A>TCA359786640MAP3K1c.2790A>T (p.Arg930Ser)
c.2412A>T (p.Arg804Ser)
c.2535A>T (p.Arg845Ser)
c.2511A>T (p.Arg837Ser)
c.2379A>T (p.Arg793Ser)
c.2301A>T (p.Arg767Ser)
n.2821A>T
5g.56881991C>ACA359786641MAP3K1c.2791C>A (p.Leu931Met)
c.2413C>A (p.Leu805Met)
c.2536C>A (p.Leu846Met)
c.2512C>A (p.Leu838Met)
c.2380C>A (p.Leu794Met)
c.2302C>A (p.Leu768Met)
n.2822C>A
5g.56881991C=CA1548139385MAP3K1c.2791C= (p.Leu931=)
c.2413C= (p.Leu805=)
c.2536C= (p.Leu846=)
c.2512C= (p.Leu838=)
c.2380C= (p.Leu794=)
c.2302C= (p.Leu768=)
n.2822C=
5g.56881991C>GCA359786642MAP3K1c.2791C>G (p.Leu931Val)
c.2413C>G (p.Leu805Val)
c.2536C>G (p.Leu846Val)
c.2512C>G (p.Leu838Val)
c.2380C>G (p.Leu794Val)
c.2302C>G (p.Leu768Val)
n.2822C>G
 dbSNP
5g.56881991C>TCA119079532MAP3K1c.2791C>T (p.Leu931=)
c.2413C>T (p.Leu805=)
c.2536C>T (p.Leu846=)
c.2512C>T (p.Leu838=)
c.2380C>T (p.Leu794=)
c.2302C>T (p.Leu768=)
n.2822C>T
 dbSNP gnomAD v2 gnomAD v4
5g.56881992T>ACA359786643MAP3K1c.2792T>A (p.Leu931Gln)
c.2414T>A (p.Leu805Gln)
c.2537T>A (p.Leu846Gln)
c.2513T>A (p.Leu838Gln)
c.2381T>A (p.Leu794Gln)
c.2303T>A (p.Leu768Gln)
n.2823T>A
5g.56881992T>CCA3273058MAP3K1c.2792T>C (p.Leu931Pro)
c.2414T>C (p.Leu805Pro)
c.2537T>C (p.Leu846Pro)
c.2513T>C (p.Leu838Pro)
c.2381T>C (p.Leu794Pro)
c.2303T>C (p.Leu768Pro)
n.2823T>C
 dbSNP ExAC gnomAD v2
5g.56881992T>GCA359786644MAP3K1c.2792T>G (p.Leu931Arg)
c.2414T>G (p.Leu805Arg)
c.2537T>G (p.Leu846Arg)
c.2513T>G (p.Leu838Arg)
c.2381T>G (p.Leu794Arg)
c.2303T>G (p.Leu768Arg)
n.2823T>G
5g.56881992T=CA1548139386MAP3K1c.2792T= (p.Leu931=)
c.2414T= (p.Leu805=)
c.2537T= (p.Leu846=)
c.2513T= (p.Leu838=)
c.2381T= (p.Leu794=)
c.2303T= (p.Leu768=)
n.2823T=
5g.56881993G>ACA444399323MAP3K1c.2793G>A (p.Leu931=)
c.2415G>A (p.Leu805=)
c.2538G>A (p.Leu846=)
c.2514G>A (p.Leu838=)
c.2382G>A (p.Leu794=)
c.2304G>A (p.Leu768=)
n.2824G>A
5g.56881993G>CCA444399324MAP3K1c.2793G>C (p.Leu931=)
c.2415G>C (p.Leu805=)
c.2538G>C (p.Leu846=)
c.2514G>C (p.Leu838=)
c.2382G>C (p.Leu794=)
c.2304G>C (p.Leu768=)
n.2824G>C
5g.56881993G>TCA444399325MAP3K1c.2793G>T (p.Leu931=)
c.2415G>T (p.Leu805=)
c.2538G>T (p.Leu846=)
c.2514G>T (p.Leu838=)
c.2382G>T (p.Leu794=)
c.2304G>T (p.Leu768=)
n.2824G>T
5g.56881994G>ACA359786645MAP3K1c.2794G>A (p.Ala932Thr)
c.2416G>A (p.Ala806Thr)
c.2539G>A (p.Ala847Thr)
c.2515G>A (p.Ala839Thr)
c.2383G>A (p.Ala795Thr)
c.2305G>A (p.Ala769Thr)
n.2825G>A
 dbSNP
5g.56881994G>CCA359786647MAP3K1c.2794G>C (p.Ala932Pro)
c.2416G>C (p.Ala806Pro)
c.2539G>C (p.Ala847Pro)
c.2515G>C (p.Ala839Pro)
c.2383G>C (p.Ala795Pro)
c.2305G>C (p.Ala769Pro)
n.2825G>C
 dbSNP
5g.56881994G=CA1548139387MAP3K1c.2794G= (p.Ala932=)
c.2416G= (p.Ala806=)
c.2539G= (p.Ala847=)
c.2515G= (p.Ala839=)
c.2383G= (p.Ala795=)
c.2305G= (p.Ala769=)
n.2825G=
5g.56881994G>TCA359786646MAP3K1c.2794G>T (p.Ala932Ser)
c.2416G>T (p.Ala806Ser)
c.2539G>T (p.Ala847Ser)
c.2515G>T (p.Ala839Ser)
c.2383G>T (p.Ala795Ser)
c.2305G>T (p.Ala769Ser)
n.2825G>T
 dbSNP
5g.56881995C>ACA359786648MAP3K1c.2795C>A (p.Ala932Asp)
c.2417C>A (p.Ala806Asp)
c.2540C>A (p.Ala847Asp)
c.2516C>A (p.Ala839Asp)
c.2384C>A (p.Ala795Asp)
c.2306C>A (p.Ala769Asp)
n.2826C>A
 dbSNP
5g.56881995C=CA1548139388MAP3K1c.2795C= (p.Ala932=)
c.2417C= (p.Ala806=)
c.2540C= (p.Ala847=)
c.2516C= (p.Ala839=)
c.2384C= (p.Ala795=)
c.2306C= (p.Ala769=)
n.2826C=
5g.56881995C>GCA359786649MAP3K1c.2795C>G (p.Ala932Gly)
c.2417C>G (p.Ala806Gly)
c.2540C>G (p.Ala847Gly)
c.2516C>G (p.Ala839Gly)
c.2384C>G (p.Ala795Gly)
c.2306C>G (p.Ala769Gly)
n.2826C>G
 gnomAD v3 gnomAD v4
5g.56881995C>TCA359786650MAP3K1c.2795C>T (p.Ala932Val)
c.2417C>T (p.Ala806Val)
c.2540C>T (p.Ala847Val)
c.2516C>T (p.Ala839Val)
c.2384C>T (p.Ala795Val)
c.2306C>T (p.Ala769Val)
n.2826C>T
 dbSNP
5g.56881996C>ACA444399326MAP3K1c.2796C>A (p.Ala932=)
c.2418C>A (p.Ala806=)
c.2541C>A (p.Ala847=)
c.2517C>A (p.Ala839=)
c.2385C>A (p.Ala795=)
c.2307C>A (p.Ala769=)
n.2827C>A
5g.56881996C=CA1548139389MAP3K1c.2796C= (p.Ala932=)
c.2418C= (p.Ala806=)
c.2541C= (p.Ala847=)
c.2517C= (p.Ala839=)
c.2385C= (p.Ala795=)
c.2307C= (p.Ala769=)
n.2827C=
5g.56881996C>GCA444399327MAP3K1c.2796C>G (p.Ala932=)
c.2418C>G (p.Ala806=)
c.2541C>G (p.Ala847=)
c.2517C>G (p.Ala839=)
c.2385C>G (p.Ala795=)
c.2307C>G (p.Ala769=)
n.2827C>G
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56881996C>TCA444399328MAP3K1c.2796C>T (p.Ala932=)
c.2418C>T (p.Ala806=)
c.2541C>T (p.Ala847=)
c.2517C>T (p.Ala839=)
c.2385C>T (p.Ala795=)
c.2307C>T (p.Ala769=)
n.2827C>T
5g.56881997A=CA1548139390MAP3K1c.2797A= (p.Ser933=)
c.2419A= (p.Ser807=)
c.2542A= (p.Ser848=)
c.2518A= (p.Ser840=)
c.2386A= (p.Ser796=)
c.2308A= (p.Ser770=)
n.2828A=
5g.56881997A>CCA359786651MAP3K1c.2797A>C (p.Ser933Arg)
c.2419A>C (p.Ser807Arg)
c.2542A>C (p.Ser848Arg)
c.2518A>C (p.Ser840Arg)
c.2386A>C (p.Ser796Arg)
c.2308A>C (p.Ser770Arg)
n.2828A>C
 dbSNP
5g.56881997A>GCA359786652MAP3K1c.2797A>G (p.Ser933Gly)
c.2419A>G (p.Ser807Gly)
c.2542A>G (p.Ser848Gly)
c.2518A>G (p.Ser840Gly)
c.2386A>G (p.Ser796Gly)
c.2308A>G (p.Ser770Gly)
n.2828A>G
5g.56881997A>TCA359786653MAP3K1c.2797A>T (p.Ser933Cys)
c.2419A>T (p.Ser807Cys)
c.2542A>T (p.Ser848Cys)
c.2518A>T (p.Ser840Cys)
c.2386A>T (p.Ser796Cys)
c.2308A>T (p.Ser770Cys)
n.2828A>T
5g.56881998G>ACA359786654MAP3K1c.2798G>A (p.Ser933Asn)
c.2420G>A (p.Ser807Asn)
c.2543G>A (p.Ser848Asn)
c.2519G>A (p.Ser840Asn)
c.2387G>A (p.Ser796Asn)
c.2309G>A (p.Ser770Asn)
n.2829G>A
 dbSNP
5g.56881998G>CCA359786655MAP3K1c.2798G>C (p.Ser933Thr)
c.2420G>C (p.Ser807Thr)
c.2543G>C (p.Ser848Thr)
c.2519G>C (p.Ser840Thr)
c.2387G>C (p.Ser796Thr)
c.2309G>C (p.Ser770Thr)
n.2829G>C
5g.56881998G>TCA359786656MAP3K1c.2798G>T (p.Ser933Ile)
c.2420G>T (p.Ser807Ile)
c.2543G>T (p.Ser848Ile)
c.2519G>T (p.Ser840Ile)
c.2387G>T (p.Ser796Ile)
c.2309G>T (p.Ser770Ile)
n.2829G>T
5g.56881999C>ACA3273059MAP3K1c.2799C>A (p.Ser933Arg)
c.2421C>A (p.Ser807Arg)
c.2544C>A (p.Ser848Arg)
c.2520C>A (p.Ser840Arg)
c.2388C>A (p.Ser796Arg)
c.2310C>A (p.Ser770Arg)
n.2830C>A
 dbSNP ExAC gnomAD v2
5g.56881999C=CA1548139391MAP3K1c.2799C= (p.Ser933=)
c.2421C= (p.Ser807=)
c.2544C= (p.Ser848=)
c.2520C= (p.Ser840=)
c.2388C= (p.Ser796=)
c.2310C= (p.Ser770=)
n.2830C=
5g.56881999C>GCA359786657MAP3K1c.2799C>G (p.Ser933Arg)
c.2421C>G (p.Ser807Arg)
c.2544C>G (p.Ser848Arg)
c.2520C>G (p.Ser840Arg)
c.2388C>G (p.Ser796Arg)
c.2310C>G (p.Ser770Arg)
n.2830C>G
 dbSNP
5g.56881999C>TCA444399329MAP3K1c.2799C>T (p.Ser933=)
c.2421C>T (p.Ser807=)
c.2544C>T (p.Ser848=)
c.2520C>T (p.Ser840=)
c.2388C>T (p.Ser796=)
c.2310C>T (p.Ser770=)
n.2830C>T
 dbSNP gnomAD v4
5g.56882000A=CA1548139392MAP3K1c.2800A= (p.Ile934=)
c.2422A= (p.Ile808=)
c.2545A= (p.Ile849=)
c.2521A= (p.Ile841=)
c.2389A= (p.Ile797=)
c.2311A= (p.Ile771=)
n.2831A=
5g.56882000A>CCA359786658MAP3K1c.2800A>C (p.Ile934Leu)
c.2422A>C (p.Ile808Leu)
c.2545A>C (p.Ile849Leu)
c.2521A>C (p.Ile841Leu)
c.2389A>C (p.Ile797Leu)
c.2311A>C (p.Ile771Leu)
n.2831A>C
5g.56882000A>GCA359786660MAP3K1c.2800A>G (p.Ile934Val)
c.2422A>G (p.Ile808Val)
c.2545A>G (p.Ile849Val)
c.2521A>G (p.Ile841Val)
c.2389A>G (p.Ile797Val)
c.2311A>G (p.Ile771Val)
n.2831A>G
 dbSNP gnomAD v2
5g.56882000A>TCA359786659MAP3K1c.2800A>T (p.Ile934Phe)
c.2422A>T (p.Ile808Phe)
c.2545A>T (p.Ile849Phe)
c.2521A>T (p.Ile841Phe)
c.2389A>T (p.Ile797Phe)
c.2311A>T (p.Ile771Phe)
n.2831A>T
5g.56882001T>ACA359786661MAP3K1c.2801T>A (p.Ile934Asn)
c.2423T>A (p.Ile808Asn)
c.2546T>A (p.Ile849Asn)
c.2522T>A (p.Ile841Asn)
c.2390T>A (p.Ile797Asn)
c.2312T>A (p.Ile771Asn)
n.2832T>A
5g.56882001T>CCA359786662MAP3K1c.2801T>C (p.Ile934Thr)
c.2423T>C (p.Ile808Thr)
c.2546T>C (p.Ile849Thr)
c.2522T>C (p.Ile841Thr)
c.2390T>C (p.Ile797Thr)
c.2312T>C (p.Ile771Thr)
n.2832T>C
5g.56882001T>GCA359786663MAP3K1c.2801T>G (p.Ile934Ser)
c.2423T>G (p.Ile808Ser)
c.2546T>G (p.Ile849Ser)
c.2522T>G (p.Ile841Ser)
c.2390T>G (p.Ile797Ser)
c.2312T>G (p.Ile771Ser)
n.2832T>G
5g.56882002T>ACA444399330MAP3K1c.2802T>A (p.Ile934=)
c.2424T>A (p.Ile808=)
c.2547T>A (p.Ile849=)
c.2523T>A (p.Ile841=)
c.2391T>A (p.Ile797=)
c.2313T>A (p.Ile771=)
n.2833T>A
5g.56882002T>CCA444399332MAP3K1c.2802T>C (p.Ile934=)
c.2424T>C (p.Ile808=)
c.2547T>C (p.Ile849=)
c.2523T>C (p.Ile841=)
c.2391T>C (p.Ile797=)
c.2313T>C (p.Ile771=)
n.2833T>C
5g.56882002T>GCA359786664MAP3K1c.2802T>G (p.Ile934Met)
c.2424T>G (p.Ile808Met)
c.2547T>G (p.Ile849Met)
c.2523T>G (p.Ile841Met)
c.2391T>G (p.Ile797Met)
c.2313T>G (p.Ile771Met)
n.2833T>G
5g.56882003T>ACA359786665MAP3K1c.2803T>A (p.Ser935Thr)
c.2425T>A (p.Ser809Thr)
c.2548T>A (p.Ser850Thr)
c.2524T>A (p.Ser842Thr)
c.2392T>A (p.Ser798Thr)
c.2314T>A (p.Ser772Thr)
n.2834T>A
5g.56882003T>CCA359786666MAP3K1c.2803T>C (p.Ser935Pro)
c.2425T>C (p.Ser809Pro)
c.2548T>C (p.Ser850Pro)
c.2524T>C (p.Ser842Pro)
c.2392T>C (p.Ser798Pro)
c.2314T>C (p.Ser772Pro)
n.2834T>C
5g.56882003T>GCA359786667MAP3K1c.2803T>G (p.Ser935Ala)
c.2425T>G (p.Ser809Ala)
c.2548T>G (p.Ser850Ala)
c.2524T>G (p.Ser842Ala)
c.2392T>G (p.Ser798Ala)
c.2314T>G (p.Ser772Ala)
n.2834T>G
 gnomAD v4
5g.56882004C>ACA359786668MAP3K1c.2804C>A (p.Ser935Ter)
c.2426C>A (p.Ser809Ter)
c.2549C>A (p.Ser850Ter)
c.2525C>A (p.Ser842Ter)
c.2393C>A (p.Ser798Ter)
c.2315C>A (p.Ser772Ter)
n.2835C>A
5g.56882004C>GCA359786669MAP3K1c.2804C>G (p.Ser935Ter)
c.2426C>G (p.Ser809Ter)
c.2549C>G (p.Ser850Ter)
c.2525C>G (p.Ser842Ter)
c.2393C>G (p.Ser798Ter)
c.2315C>G (p.Ser772Ter)
n.2835C>G
5g.56882004C>TCA359786670MAP3K1c.2804C>T (p.Ser935Leu)
c.2426C>T (p.Ser809Leu)
c.2549C>T (p.Ser850Leu)
c.2525C>T (p.Ser842Leu)
c.2393C>T (p.Ser798Leu)
c.2315C>T (p.Ser772Leu)
n.2835C>T
5g.56882005A>CCA444399333MAP3K1c.2805A>C (p.Ser935=)
c.2427A>C (p.Ser809=)
c.2550A>C (p.Ser850=)
c.2526A>C (p.Ser842=)
c.2394A>C (p.Ser798=)
c.2316A>C (p.Ser772=)
n.2836A>C
5g.56882005A>GCA444399334MAP3K1c.2805A>G (p.Ser935=)
c.2427A>G (p.Ser809=)
c.2550A>G (p.Ser850=)
c.2526A>G (p.Ser842=)
c.2394A>G (p.Ser798=)
c.2316A>G (p.Ser772=)
n.2836A>G
5g.56882005A>TCA444399335MAP3K1c.2805A>T (p.Ser935=)
c.2427A>T (p.Ser809=)
c.2550A>T (p.Ser850=)
c.2526A>T (p.Ser842=)
c.2394A>T (p.Ser798=)
c.2316A>T (p.Ser772=)
n.2836A>T
5g.56882006G>ACA359786671MAP3K1c.2806G>A (p.Val936Ile)
c.2428G>A (p.Val810Ile)
c.2551G>A (p.Val851Ile)
c.2527G>A (p.Val843Ile)
c.2395G>A (p.Val799Ile)
c.2317G>A (p.Val773Ile)
n.2837G>A
 dbSNP gnomAD v3 gnomAD v4
5g.56882006G>CCA359786672MAP3K1c.2806G>C (p.Val936Leu)
c.2428G>C (p.Val810Leu)
c.2551G>C (p.Val851Leu)
c.2527G>C (p.Val843Leu)
c.2395G>C (p.Val799Leu)
c.2317G>C (p.Val773Leu)
n.2837G>C
5g.56882006G=CA1548139393MAP3K1c.2806G= (p.Val936=)
c.2428G= (p.Val810=)
c.2551G= (p.Val851=)
c.2527G= (p.Val843=)
c.2395G= (p.Val799=)
c.2317G= (p.Val773=)
n.2837G=
5g.56882006G>TCA359786673MAP3K1c.2806G>T (p.Val936Leu)
c.2428G>T (p.Val810Leu)
c.2551G>T (p.Val851Leu)
c.2527G>T (p.Val843Leu)
c.2395G>T (p.Val799Leu)
c.2317G>T (p.Val773Leu)
n.2837G>T
 dbSNP gnomAD v3 gnomAD v4
5g.56882007T>ACA359786674MAP3K1c.2807T>A (p.Val936Glu)
c.2429T>A (p.Val810Glu)
c.2552T>A (p.Val851Glu)
c.2528T>A (p.Val843Glu)
c.2396T>A (p.Val799Glu)
c.2318T>A (p.Val773Glu)
n.2838T>A
5g.56882007T>CCA359786676MAP3K1c.2807T>C (p.Val936Ala)
c.2429T>C (p.Val810Ala)
c.2552T>C (p.Val851Ala)
c.2528T>C (p.Val843Ala)
c.2396T>C (p.Val799Ala)
c.2318T>C (p.Val773Ala)
n.2838T>C
5g.56882007T>GCA359786675MAP3K1c.2807T>G (p.Val936Gly)
c.2429T>G (p.Val810Gly)
c.2552T>G (p.Val851Gly)
c.2528T>G (p.Val843Gly)
c.2396T>G (p.Val799Gly)
c.2318T>G (p.Val773Gly)
n.2838T>G
5g.56882008A=CA1548139394MAP3K1c.2808A= (p.Val936=)
c.2430A= (p.Val810=)
c.2553A= (p.Val851=)
c.2529A= (p.Val843=)
c.2397A= (p.Val799=)
c.2319A= (p.Val773=)
n.2839A=
5g.56882008A>CCA444399339MAP3K1c.2808A>C (p.Val936=)
c.2430A>C (p.Val810=)
c.2553A>C (p.Val851=)
c.2529A>C (p.Val843=)
c.2397A>C (p.Val799=)
c.2319A>C (p.Val773=)
n.2839A>C
5g.56882008A>GCA444399340MAP3K1c.2808A>G (p.Val936=)
c.2430A>G (p.Val810=)
c.2553A>G (p.Val851=)
c.2529A>G (p.Val843=)
c.2397A>G (p.Val799=)
c.2319A>G (p.Val773=)
n.2839A>G
 dbSNP gnomAD v2 gnomAD v4
5g.56882008A>TCA444399341MAP3K1c.2808A>T (p.Val936=)
c.2430A>T (p.Val810=)
c.2553A>T (p.Val851=)
c.2529A>T (p.Val843=)
c.2397A>T (p.Val799=)
c.2319A>T (p.Val773=)
n.2839A>T
5g.56882009G>ACA359786677MAP3K1c.2809G>A (p.Gly937Arg)
c.2431G>A (p.Gly811Arg)
c.2554G>A (p.Gly852Arg)
c.2530G>A (p.Gly844Arg)
c.2398G>A (p.Gly800Arg)
c.2320G>A (p.Gly774Arg)
n.2840G>A
5g.56882009G>CCA359786678MAP3K1c.2809G>C (p.Gly937Arg)
c.2431G>C (p.Gly811Arg)
c.2554G>C (p.Gly852Arg)
c.2530G>C (p.Gly844Arg)
c.2398G>C (p.Gly800Arg)
c.2320G>C (p.Gly774Arg)
n.2840G>C
5g.56882009G>TCA359786679MAP3K1c.2809G>T (p.Gly937Ter)
c.2431G>T (p.Gly811Ter)
c.2554G>T (p.Gly852Ter)
c.2530G>T (p.Gly844Ter)
c.2398G>T (p.Gly800Ter)
c.2320G>T (p.Gly774Ter)
n.2840G>T
5g.56882010G>ACA359786680MAP3K1c.2810G>A (p.Gly937Glu)
c.2432G>A (p.Gly811Glu)
c.2555G>A (p.Gly852Glu)
c.2531G>A (p.Gly844Glu)
c.2399G>A (p.Gly800Glu)
c.2321G>A (p.Gly774Glu)
n.2841G>A
 dbSNP
5g.56882010G>CCA359786681MAP3K1c.2810G>C (p.Gly937Ala)
c.2432G>C (p.Gly811Ala)
c.2555G>C (p.Gly852Ala)
c.2531G>C (p.Gly844Ala)
c.2399G>C (p.Gly800Ala)
c.2321G>C (p.Gly774Ala)
n.2841G>C
5g.56882010G>TCA359786682MAP3K1c.2810G>T (p.Gly937Val)
c.2432G>T (p.Gly811Val)
c.2555G>T (p.Gly852Val)
c.2531G>T (p.Gly844Val)
c.2399G>T (p.Gly800Val)
c.2321G>T (p.Gly774Val)
n.2841G>T
 dbSNP
5g.56882011A=CA1548139395MAP3K1c.2811A= (p.Gly937=)
c.2433A= (p.Gly811=)
c.2556A= (p.Gly852=)
c.2532A= (p.Gly844=)
c.2400A= (p.Gly800=)
c.2322A= (p.Gly774=)
n.2842A=
5g.56882011A>CCA444399343MAP3K1c.2811A>C (p.Gly937=)
c.2433A>C (p.Gly811=)
c.2556A>C (p.Gly852=)
c.2532A>C (p.Gly844=)
c.2400A>C (p.Gly800=)
c.2322A>C (p.Gly774=)
n.2842A>C
5g.56882011A>GCA444399345MAP3K1c.2811A>G (p.Gly937=)
c.2433A>G (p.Gly811=)
c.2556A>G (p.Gly852=)
c.2532A>G (p.Gly844=)
c.2400A>G (p.Gly800=)
c.2322A>G (p.Gly774=)
n.2842A>G
5g.56882011A>TCA444399347MAP3K1c.2811A>T (p.Gly937=)
c.2433A>T (p.Gly811=)
c.2556A>T (p.Gly852=)
c.2532A>T (p.Gly844=)
c.2400A>T (p.Gly800=)
c.2322A>T (p.Gly774=)
n.2842A>T
5g.56882011_56882012insAATCAAACAATTGGCAAGAACTTCTTGGCCGCA3273060MAP3K1c.2811_2812insAATCAAACAATTGGCAAGAACTTCTTGGCCG (p.Pro938AsnfsTer13)
c.2433_2434insAATCAAACAATTGGCAAGAACTTCTTGGCCG (p.Pro812AsnfsTer13)
c.2556_2557insAATCAAACAATTGGCAAGAACTTCTTGGCCG (p.Pro853AsnfsTer13)
c.2532_2533insAATCAAACAATTGGCAAGAACTTCTTGGCCG (p.Pro845AsnfsTer13)
c.2400_2401insAATCAAACAATTGGCAAGAACTTCTTGGCCG (p.Pro801AsnfsTer13)
c.2322_2323insAATCAAACAATTGGCAAGAACTTCTTGGCCG (p.Pro775AsnfsTer13)
n.2842_2843insAATCAAACAATTGGCAAGAACTTCTTGGCCG
 dbSNP ExAC
5g.56882012C>ACA3273061MAP3K1c.2812C>A (p.Pro938Thr)
c.2434C>A (p.Pro812Thr)
c.2557C>A (p.Pro853Thr)
c.2533C>A (p.Pro845Thr)
c.2401C>A (p.Pro801Thr)
c.2323C>A (p.Pro775Thr)
n.2843C>A
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882012C=CA1548139396MAP3K1c.2812C= (p.Pro938=)
c.2434C= (p.Pro812=)
c.2557C= (p.Pro853=)
c.2533C= (p.Pro845=)
c.2401C= (p.Pro801=)
c.2323C= (p.Pro775=)
n.2843C=
5g.56882012C>GCA359786683MAP3K1c.2812C>G (p.Pro938Ala)
c.2434C>G (p.Pro812Ala)
c.2557C>G (p.Pro853Ala)
c.2533C>G (p.Pro845Ala)
c.2401C>G (p.Pro801Ala)
c.2323C>G (p.Pro775Ala)
n.2843C>G
5g.56882012C>TCA359786684MAP3K1c.2812C>T (p.Pro938Ser)
c.2434C>T (p.Pro812Ser)
c.2557C>T (p.Pro853Ser)
c.2533C>T (p.Pro845Ser)
c.2401C>T (p.Pro801Ser)
c.2323C>T (p.Pro775Ser)
n.2843C>T
 gnomAD v4
5g.56882018_56882161delCA2580611859MAP3K1c.2818_2961del (p.Ser940_Ser987del)
c.2440_2583del (p.Ser814_Ser861del)
c.2563_2706del (p.Ser855_Ser902del)
c.2539_2682del (p.Ser847_Ser894del)
c.2407_2550del (p.Ser803_Ser850del)
c.2329_2472del (p.Ser777_Ser824del)
n.2849_2992del
5g.56882013C>ACA359786687MAP3K1c.2813C>A (p.Pro938His)
c.2435C>A (p.Pro812His)
c.2558C>A (p.Pro853His)
c.2534C>A (p.Pro845His)
c.2402C>A (p.Pro801His)
c.2324C>A (p.Pro775His)
n.2844C>A
5g.56882013C>GCA359786686MAP3K1c.2813C>G (p.Pro938Arg)
c.2435C>G (p.Pro812Arg)
c.2558C>G (p.Pro853Arg)
c.2534C>G (p.Pro845Arg)
c.2402C>G (p.Pro801Arg)
c.2324C>G (p.Pro775Arg)
n.2844C>G
 gnomAD v4
5g.56882013C>TCA359786685MAP3K1c.2813C>T (p.Pro938Leu)
c.2435C>T (p.Pro812Leu)
c.2558C>T (p.Pro853Leu)
c.2534C>T (p.Pro845Leu)
c.2402C>T (p.Pro801Leu)
c.2324C>T (p.Pro775Leu)
n.2844C>T
 gnomAD v3 gnomAD v4
5g.56882014T>ACA444399349MAP3K1c.2814T>A (p.Pro938=)
c.2436T>A (p.Pro812=)
c.2559T>A (p.Pro853=)
c.2535T>A (p.Pro845=)
c.2403T>A (p.Pro801=)
c.2325T>A (p.Pro775=)
n.2845T>A
5g.56882014T>CCA444399350MAP3K1c.2814T>C (p.Pro938=)
c.2436T>C (p.Pro812=)
c.2559T>C (p.Pro853=)
c.2535T>C (p.Pro845=)
c.2403T>C (p.Pro801=)
c.2325T>C (p.Pro775=)
n.2845T>C
 gnomAD v4
5g.56882014T>GCA444399351MAP3K1c.2814T>G (p.Pro938=)
c.2436T>G (p.Pro812=)
c.2559T>G (p.Pro853=)
c.2535T>G (p.Pro845=)
c.2403T>G (p.Pro801=)
c.2325T>G (p.Pro775=)
n.2845T>G
5g.56882015T>ACA359786688MAP3K1c.2815T>A (p.Ser939Thr)
c.2437T>A (p.Ser813Thr)
c.2560T>A (p.Ser854Thr)
c.2536T>A (p.Ser846Thr)
c.2404T>A (p.Ser802Thr)
c.2326T>A (p.Ser776Thr)
n.2846T>A
5g.56882015T>CCA3273062MAP3K1c.2815T>C (p.Ser939Pro)
c.2437T>C (p.Ser813Pro)
c.2560T>C (p.Ser854Pro)
c.2536T>C (p.Ser846Pro)
c.2404T>C (p.Ser802Pro)
c.2326T>C (p.Ser776Pro)
n.2846T>C
 dbSNP ExAC gnomAD v3 gnomAD v4
5g.56882015T>GCA3273063MAP3K1c.2815T>G (p.Ser939Ala)
c.2437T>G (p.Ser813Ala)
c.2560T>G (p.Ser854Ala)
c.2536T>G (p.Ser846Ala)
c.2404T>G (p.Ser802Ala)
c.2326T>G (p.Ser776Ala)
n.2846T>G
 dbSNP ExAC gnomAD v2 gnomAD v4
5g.56882015T=CA1548139398MAP3K1c.2815T= (p.Ser939=)
c.2437T= (p.Ser813=)
c.2560T= (p.Ser854=)
c.2536T= (p.Ser846=)
c.2404T= (p.Ser802=)
c.2326T= (p.Ser776=)
n.2846T=
5g.56882015_56882024delinsTCTAGTTCAACA1548139397MAP3K1c.2815_2824delinsTCTAGTTCAA (p.Ser939=)
c.2437_2446delinsTCTAGTTCAA (p.Ser813=)
c.2560_2569delinsTCTAGTTCAA (p.Ser854=)
c.2536_2545delinsTCTAGTTCAA (p.Ser846=)
c.2404_2413delinsTCTAGTTCAA (p.Ser802=)
c.2326_2335delinsTCTAGTTCAA (p.Ser776=)
n.2846_2855delinsTCTAGTTCAA
5g.56882016C>ACA359786689MAP3K1c.2816C>A (p.Ser939Tyr)
c.2438C>A (p.Ser813Tyr)
c.2561C>A (p.Ser854Tyr)
c.2537C>A (p.Ser846Tyr)
c.2405C>A (p.Ser802Tyr)
c.2327C>A (p.Ser776Tyr)
n.2847C>A
5g.56882016C=CA1548139399MAP3K1c.2816C= (p.Ser939=)
c.2438C= (p.Ser813=)
c.2561C= (p.Ser854=)
c.2537C= (p.Ser846=)
c.2405C= (p.Ser802=)
c.2327C= (p.Ser776=)
n.2847C=
5g.56882016C>GCA3273064MAP3K1c.2816C>G (p.Ser939Cys)
c.2438C>G (p.Ser813Cys)
c.2561C>G (p.Ser854Cys)
c.2537C>G (p.Ser846Cys)
c.2405C>G (p.Ser802Cys)
c.2327C>G (p.Ser776Cys)
n.2847C>G
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882016C>TCA359786690MAP3K1c.2816C>T (p.Ser939Phe)
c.2438C>T (p.Ser813Phe)
c.2561C>T (p.Ser854Phe)
c.2537C>T (p.Ser846Phe)
c.2405C>T (p.Ser802Phe)
c.2327C>T (p.Ser776Phe)
n.2847C>T
5g.56882017_56882025delCA559801260MAP3K1c.2817_2825del (p.Ser940_Thr942del)
c.2439_2447del (p.Ser814_Thr816del)
c.2562_2570del (p.Ser855_Thr857del)
c.2538_2546del (p.Ser847_Thr849del)
c.2406_2414del (p.Ser803_Thr805del)
c.2328_2336del (p.Ser777_Thr779del)
n.2848_2856del
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56882016_56882057delCA645557016MAP3K1c.2816_2857del (p.Ser939Ter)
c.2438_2479del (p.Ser813Ter)
c.2561_2602del (p.Ser854Ter)
c.2537_2578del (p.Ser846Ter)
c.2405_2446del (p.Ser802Ter)
c.2327_2368del (p.Ser776Ter)
n.2847_2888del
 COSMIC
5g.56882017T>ACA444399352MAP3K1c.2817T>A (p.Ser939=)
c.2439T>A (p.Ser813=)
c.2562T>A (p.Ser854=)
c.2538T>A (p.Ser846=)
c.2406T>A (p.Ser802=)
c.2328T>A (p.Ser776=)
n.2848T>A
5g.56882017T>CCA444399353MAP3K1c.2817T>C (p.Ser939=)
c.2439T>C (p.Ser813=)
c.2562T>C (p.Ser854=)
c.2538T>C (p.Ser846=)
c.2406T>C (p.Ser802=)
c.2328T>C (p.Ser776=)
n.2848T>C
5g.56882017T>GCA444399354MAP3K1c.2817T>G (p.Ser939=)
c.2439T>G (p.Ser813=)
c.2562T>G (p.Ser854=)
c.2538T>G (p.Ser846=)
c.2406T>G (p.Ser802=)
c.2328T>G (p.Ser776=)
n.2848T>G
 gnomAD v4
5g.56882018A>CCA359786691MAP3K1c.2818A>C (p.Ser940Arg)
c.2440A>C (p.Ser814Arg)
c.2563A>C (p.Ser855Arg)
c.2539A>C (p.Ser847Arg)
c.2407A>C (p.Ser803Arg)
c.2329A>C (p.Ser777Arg)
n.2849A>C
5g.56882018A>GCA359786692MAP3K1c.2818A>G (p.Ser940Gly)
c.2440A>G (p.Ser814Gly)
c.2563A>G (p.Ser855Gly)
c.2539A>G (p.Ser847Gly)
c.2407A>G (p.Ser803Gly)
c.2329A>G (p.Ser777Gly)
n.2849A>G
5g.56882018A>TCA359786693MAP3K1c.2818A>T (p.Ser940Cys)
c.2440A>T (p.Ser814Cys)
c.2563A>T (p.Ser855Cys)
c.2539A>T (p.Ser847Cys)
c.2407A>T (p.Ser803Cys)
c.2329A>T (p.Ser777Cys)
n.2849A>T
5g.56882019G>ACA359786694MAP3K1c.2819G>A (p.Ser940Asn)
c.2441G>A (p.Ser814Asn)
c.2564G>A (p.Ser855Asn)
c.2540G>A (p.Ser847Asn)
c.2408G>A (p.Ser803Asn)
c.2330G>A (p.Ser777Asn)
n.2850G>A
 gnomAD v4
5g.56882019G>CCA359786695MAP3K1c.2819G>C (p.Ser940Thr)
c.2441G>C (p.Ser814Thr)
c.2564G>C (p.Ser855Thr)
c.2540G>C (p.Ser847Thr)
c.2408G>C (p.Ser803Thr)
c.2330G>C (p.Ser777Thr)
n.2850G>C
5g.56882019G>TCA359786696MAP3K1c.2819G>T (p.Ser940Ile)
c.2441G>T (p.Ser814Ile)
c.2564G>T (p.Ser855Ile)
c.2540G>T (p.Ser847Ile)
c.2408G>T (p.Ser803Ile)
c.2330G>T (p.Ser777Ile)
n.2850G>T
5g.56882020T>ACA359786697MAP3K1c.2820T>A (p.Ser940Arg)
c.2442T>A (p.Ser814Arg)
c.2565T>A (p.Ser855Arg)
c.2541T>A (p.Ser847Arg)
c.2409T>A (p.Ser803Arg)
c.2331T>A (p.Ser777Arg)
n.2851T>A
5g.56882020T>CCA444399358MAP3K1c.2820T>C (p.Ser940=)
c.2442T>C (p.Ser814=)
c.2565T>C (p.Ser855=)
c.2541T>C (p.Ser847=)
c.2409T>C (p.Ser803=)
c.2331T>C (p.Ser777=)
n.2851T>C
5g.56882020T>GCA359786698MAP3K1c.2820T>G (p.Ser940Arg)
c.2442T>G (p.Ser814Arg)
c.2565T>G (p.Ser855Arg)
c.2541T>G (p.Ser847Arg)
c.2409T>G (p.Ser803Arg)
c.2331T>G (p.Ser777Arg)
n.2851T>G
5g.56882021T>ACA359786701MAP3K1c.2821T>A (p.Ser941Thr)
c.2443T>A (p.Ser815Thr)
c.2566T>A (p.Ser856Thr)
c.2542T>A (p.Ser848Thr)
c.2410T>A (p.Ser804Thr)
c.2332T>A (p.Ser778Thr)
n.2852T>A
5g.56882021T>CCA359786700MAP3K1c.2821T>C (p.Ser941Pro)
c.2443T>C (p.Ser815Pro)
c.2566T>C (p.Ser856Pro)
c.2542T>C (p.Ser848Pro)
c.2410T>C (p.Ser804Pro)
c.2332T>C (p.Ser778Pro)
n.2852T>C
5g.56882021T>GCA359786699MAP3K1c.2821T>G (p.Ser941Ala)
c.2443T>G (p.Ser815Ala)
c.2566T>G (p.Ser856Ala)
c.2542T>G (p.Ser848Ala)
c.2410T>G (p.Ser804Ala)
c.2332T>G (p.Ser778Ala)
n.2852T>G
5g.56882021T=CA2742039477MAP3K1c.2821T= (p.Ser941=)
c.2443T= (p.Ser815=)
c.2566T= (p.Ser856=)
c.2542T= (p.Ser848=)
c.2410T= (p.Ser804=)
c.2332T= (p.Ser778=)
n.2852T=
5g.56882021_56882023delCA2708985357MAP3K1c.2821_2823del (p.Ser941del)
c.2443_2445del (p.Ser815del)
c.2566_2568del (p.Ser856del)
c.2542_2544del (p.Ser848del)
c.2410_2412del (p.Ser804del)
c.2332_2334del (p.Ser778del)
n.2852_2854del
 dbSNP
5g.56882021_56882024delCA2673909977MAP3K1c.2821_2824del (p.Ser941GlnfsTer26)
c.2443_2446del (p.Ser815GlnfsTer26)
c.2566_2569del (p.Ser856GlnfsTer26)
c.2542_2545del (p.Ser848GlnfsTer26)
c.2410_2413del (p.Ser804GlnfsTer26)
c.2332_2335del (p.Ser778GlnfsTer26)
n.2852_2855del
 gnomAD v4
5g.56882021_56882024delinsTCAACA2497029635MAP3K1c.2821_2824delinsTCAA (p.Ser941=)
c.2443_2446delinsTCAA (p.Ser815=)
c.2566_2569delinsTCAA (p.Ser856=)
c.2542_2545delinsTCAA (p.Ser848=)
c.2410_2413delinsTCAA (p.Ser804=)
c.2332_2335delinsTCAA (p.Ser778=)
n.2852_2855delinsTCAA
5g.56882021_56882036delinsTCAACAACAACAACAACA1548139400MAP3K1c.2821_2836delinsTCAACAACAACAACAA (p.Ser941=)
c.2443_2458delinsTCAACAACAACAACAA (p.Ser815=)
c.2566_2581delinsTCAACAACAACAACAA (p.Ser856=)
c.2542_2557delinsTCAACAACAACAACAA (p.Ser848=)
c.2410_2425delinsTCAACAACAACAACAA (p.Ser804=)
c.2332_2347delinsTCAACAACAACAACAA (p.Ser778=)
n.2852_2867delinsTCAACAACAACAACAA
5g.56882022C>ACA359786702MAP3K1c.2822C>A (p.Ser941Ter)
c.2444C>A (p.Ser815Ter)
c.2567C>A (p.Ser856Ter)
c.2543C>A (p.Ser848Ter)
c.2411C>A (p.Ser804Ter)
c.2333C>A (p.Ser778Ter)
n.2853C>A
5g.56882022C=CA1548139401MAP3K1c.2822C= (p.Ser941=)
c.2444C= (p.Ser815=)
c.2567C= (p.Ser856=)
c.2543C= (p.Ser848=)
c.2411C= (p.Ser804=)
c.2333C= (p.Ser778=)
n.2853C=
5g.56882022C>GCA359786703MAP3K1c.2822C>G (p.Ser941Ter)
c.2444C>G (p.Ser815Ter)
c.2567C>G (p.Ser856Ter)
c.2543C>G (p.Ser848Ter)
c.2411C>G (p.Ser804Ter)
c.2333C>G (p.Ser778Ter)
n.2853C>G
5g.56882022C>TCA359786704MAP3K1c.2822C>T (p.Ser941Leu)
c.2444C>T (p.Ser815Leu)
c.2567C>T (p.Ser856Leu)
c.2543C>T (p.Ser848Leu)
c.2411C>T (p.Ser804Leu)
c.2333C>T (p.Ser778Leu)
n.2853C>T
 dbSNP gnomAD v2 gnomAD v4
5g.56882045_56882047dupCA3273067MAP3K1c.2845_2847dup (p.Thr949_Glu950insThr)
c.2467_2469dup (p.Thr823_Glu824insThr)
c.2590_2592dup (p.Thr864_Glu865insThr)
c.2566_2568dup (p.Thr856_Glu857insThr)
c.2434_2436dup (p.Thr812_Glu813insThr)
c.2356_2358dup (p.Thr786_Glu787insThr)
n.2876_2878dup
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882042_56882047dupCA3273070MAP3K1c.2842_2847dup (p.Thr949_Glu950insThrThr)
c.2464_2469dup (p.Thr823_Glu824insThrThr)
c.2587_2592dup (p.Thr864_Glu865insThrThr)
c.2563_2568dup (p.Thr856_Glu857insThrThr)
c.2431_2436dup (p.Thr812_Glu813insThrThr)
c.2353_2358dup (p.Thr786_Glu787insThrThr)
n.2873_2878dup
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882039_56882047dupCA2673909979MAP3K1c.2839_2847dup (p.Thr949_Glu950insThrThrThr)
c.2461_2469dup (p.Thr823_Glu824insThrThrThr)
c.2584_2592dup (p.Thr864_Glu865insThrThrThr)
c.2560_2568dup (p.Thr856_Glu857insThrThrThr)
c.2428_2436dup (p.Thr812_Glu813insThrThrThr)
c.2350_2358dup (p.Thr786_Glu787insThrThrThr)
n.2870_2878dup
 gnomAD v4
5g.56882036_56882047dupCA2673909978MAP3K1c.2836_2847dup (p.Thr949_Glu950insThrThrThrThr)
c.2458_2469dup (p.Thr823_Glu824insThrThrThrThr)
c.2581_2592dup (p.Thr864_Glu865insThrThrThrThr)
c.2557_2568dup (p.Thr856_Glu857insThrThrThrThr)
c.2425_2436dup (p.Thr812_Glu813insThrThrThrThr)
c.2347_2358dup (p.Thr786_Glu787insThrThrThrThr)
n.2867_2878dup
 gnomAD v4
5g.56882045_56882047delCA3273066MAP3K1c.2845_2847del (p.Thr949del)
c.2467_2469del (p.Thr823del)
c.2590_2592del (p.Thr864del)
c.2566_2568del (p.Thr856del)
c.2434_2436del (p.Thr812del)
c.2356_2358del (p.Thr786del)
n.2876_2878del
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4 COSMIC COSMIC COSMIC
5g.56882042_56882047delCA3273065MAP3K1c.2842_2847del (p.Thr948_Thr949del)
c.2464_2469del (p.Thr822_Thr823del)
c.2587_2592del (p.Thr863_Thr864del)
c.2563_2568del (p.Thr855_Thr856del)
c.2431_2436del (p.Thr811_Thr812del)
c.2353_2358del (p.Thr785_Thr786del)
n.2873_2878del
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4 COSMIC
5g.56882039_56882047delCA3273069MAP3K1c.2839_2847del (p.Thr947_Thr949del)
c.2461_2469del (p.Thr821_Thr823del)
c.2584_2592del (p.Thr862_Thr864del)
c.2560_2568del (p.Thr854_Thr856del)
c.2428_2436del (p.Thr810_Thr812del)
c.2350_2358del (p.Thr784_Thr786del)
n.2870_2878del
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882036_56882047delCA3273068MAP3K1c.2836_2847del (p.Thr946_Thr949del)
c.2458_2469del (p.Thr820_Thr823del)
c.2581_2592del (p.Thr861_Thr864del)
c.2557_2568del (p.Thr853_Thr856del)
c.2425_2436del (p.Thr809_Thr812del)
c.2347_2358del (p.Thr783_Thr786del)
n.2867_2878del
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882033_56882047delCA1076343331MAP3K1c.2833_2847del (p.Thr945_Thr949del)
c.2455_2469del (p.Thr819_Thr823del)
c.2578_2592del (p.Thr860_Thr864del)
c.2554_2568del (p.Thr852_Thr856del)
c.2422_2436del (p.Thr808_Thr812del)
c.2344_2358del (p.Thr782_Thr786del)
n.2864_2878del
 dbSNP gnomAD v3 gnomAD v4
5g.56882023A=CA1548139402MAP3K1c.2823A= (p.Ser941=)
c.2445A= (p.Ser815=)
c.2568A= (p.Ser856=)
c.2544A= (p.Ser848=)
c.2412A= (p.Ser804=)
c.2334A= (p.Ser778=)
n.2854A=
5g.56882023A>CCA444399365MAP3K1c.2823A>C (p.Ser941=)
c.2445A>C (p.Ser815=)
c.2568A>C (p.Ser856=)
c.2544A>C (p.Ser848=)
c.2412A>C (p.Ser804=)
c.2334A>C (p.Ser778=)
n.2854A>C
5g.56882023A>GCA444399366MAP3K1c.2823A>G (p.Ser941=)
c.2445A>G (p.Ser815=)
c.2568A>G (p.Ser856=)
c.2544A>G (p.Ser848=)
c.2412A>G (p.Ser804=)
c.2334A>G (p.Ser778=)
n.2854A>G
 dbSNP
5g.56882023A>TCA444399367MAP3K1c.2823A>T (p.Ser941=)
c.2445A>T (p.Ser815=)
c.2568A>T (p.Ser856=)
c.2544A>T (p.Ser848=)
c.2412A>T (p.Ser804=)
c.2334A>T (p.Ser778=)
n.2854A>T
 dbSNP
5g.56882024A=CA1548139403MAP3K1c.2824A= (p.Thr942=)
c.2446A= (p.Thr816=)
c.2569A= (p.Thr857=)
c.2545A= (p.Thr849=)
c.2413A= (p.Thr805=)
c.2335A= (p.Thr779=)
n.2855A=
5g.56882024A>CCA359786709MAP3K1c.2824A>C (p.Thr942Pro)
c.2446A>C (p.Thr816Pro)
c.2569A>C (p.Thr857Pro)
c.2545A>C (p.Thr849Pro)
c.2413A>C (p.Thr805Pro)
c.2335A>C (p.Thr779Pro)
n.2855A>C
5g.56882024A>GCA359786710MAP3K1c.2824A>G (p.Thr942Ala)
c.2446A>G (p.Thr816Ala)
c.2569A>G (p.Thr857Ala)
c.2545A>G (p.Thr849Ala)
c.2413A>G (p.Thr805Ala)
c.2335A>G (p.Thr779Ala)
n.2855A>G
 dbSNP
5g.56882024A>TCA359786712MAP3K1c.2824A>T (p.Thr942Ser)
c.2446A>T (p.Thr816Ser)
c.2569A>T (p.Thr857Ser)
c.2545A>T (p.Thr849Ser)
c.2413A>T (p.Thr805Ser)
c.2335A>T (p.Thr779Ser)
n.2855A>T
 dbSNP
5g.56882025_56882026delCA444399368MAP3K1c.2825_2826del (p.Thr942AsnfsTer?)
c.2447_2448del (p.Thr816AsnfsTer?)
c.2570_2571del (p.Thr857AsnfsTer?)
c.2546_2547del (p.Thr849AsnfsTer?)
c.2414_2415del (p.Thr805AsnfsTer?)
c.2336_2337del (p.Thr779AsnfsTer?)
n.2856_2857del
5g.56882025delCA444399369MAP3K1c.2825del (p.Thr942LysfsTer26)
c.2447del (p.Thr816LysfsTer26)
c.2570del (p.Thr857LysfsTer26)
c.2546del (p.Thr849LysfsTer26)
c.2414del (p.Thr805LysfsTer26)
c.2336del (p.Thr779LysfsTer26)
n.2856del
5g.56882025C>ACA119079646MAP3K1c.2825C>A (p.Thr942Lys)
c.2447C>A (p.Thr816Lys)
c.2570C>A (p.Thr857Lys)
c.2546C>A (p.Thr849Lys)
c.2414C>A (p.Thr805Lys)
c.2336C>A (p.Thr779Lys)
n.2856C>A
 dbSNP gnomAD v2
5g.56882025C=CA1548139404MAP3K1c.2825C= (p.Thr942=)
c.2447C= (p.Thr816=)
c.2570C= (p.Thr857=)
c.2546C= (p.Thr849=)
c.2414C= (p.Thr805=)
c.2336C= (p.Thr779=)
n.2856C=
5g.56882025C>GCA359786717MAP3K1c.2825C>G (p.Thr942Arg)
c.2447C>G (p.Thr816Arg)
c.2570C>G (p.Thr857Arg)
c.2546C>G (p.Thr849Arg)
c.2414C>G (p.Thr805Arg)
c.2336C>G (p.Thr779Arg)
n.2856C>G
5g.56882025C>TCA359786714MAP3K1c.2825C>T (p.Thr942Ile)
c.2447C>T (p.Thr816Ile)
c.2570C>T (p.Thr857Ile)
c.2546C>T (p.Thr849Ile)
c.2414C>T (p.Thr805Ile)
c.2336C>T (p.Thr779Ile)
n.2856C>T
 dbSNP gnomAD v4
5g.56882029_56882030insTCAACACA2708985393MAP3K1c.2829_2830insTCAACA (p.Thr943_Thr944insSerThr)
c.2451_2452insTCAACA (p.Thr817_Thr818insSerThr)
c.2574_2575insTCAACA (p.Thr858_Thr859insSerThr)
c.2550_2551insTCAACA (p.Thr850_Thr851insSerThr)
c.2418_2419insTCAACA (p.Thr806_Thr807insSerThr)
c.2340_2341insTCAACA (p.Thr780_Thr781insSerThr)
n.2860_2861insTCAACA
 dbSNP
5g.56882026A=CA1548139405MAP3K1c.2826A= (p.Thr942=)
c.2448A= (p.Thr816=)
c.2571A= (p.Thr857=)
c.2547A= (p.Thr849=)
c.2415A= (p.Thr805=)
c.2337A= (p.Thr779=)
n.2857A=
5g.56882026A>CCA444399375MAP3K1c.2826A>C (p.Thr942=)
c.2448A>C (p.Thr816=)
c.2571A>C (p.Thr857=)
c.2547A>C (p.Thr849=)
c.2415A>C (p.Thr805=)
c.2337A>C (p.Thr779=)
n.2857A>C
5g.56882026A>GCA444399373MAP3K1c.2826A>G (p.Thr942=)
c.2448A>G (p.Thr816=)
c.2571A>G (p.Thr857=)
c.2547A>G (p.Thr849=)
c.2415A>G (p.Thr805=)
c.2337A>G (p.Thr779=)
n.2857A>G
 dbSNP gnomAD v2 gnomAD v4
5g.56882026A>TCA444399374MAP3K1c.2826A>T (p.Thr942=)
c.2448A>T (p.Thr816=)
c.2571A>T (p.Thr857=)
c.2547A>T (p.Thr849=)
c.2415A>T (p.Thr805=)
c.2337A>T (p.Thr779=)
n.2857A>T
5g.56882027A=CA1548139406MAP3K1c.2827A= (p.Thr943=)
c.2449A= (p.Thr817=)
c.2572A= (p.Thr858=)
c.2548A= (p.Thr850=)
c.2416A= (p.Thr806=)
c.2338A= (p.Thr780=)
n.2858A=
5g.56882027A>CCA359786719MAP3K1c.2827A>C (p.Thr943Pro)
c.2449A>C (p.Thr817Pro)
c.2572A>C (p.Thr858Pro)
c.2548A>C (p.Thr850Pro)
c.2416A>C (p.Thr806Pro)
c.2338A>C (p.Thr780Pro)
n.2858A>C
5g.56882027A>GCA3273072MAP3K1c.2827A>G (p.Thr943Ala)
c.2449A>G (p.Thr817Ala)
c.2572A>G (p.Thr858Ala)
c.2548A>G (p.Thr850Ala)
c.2416A>G (p.Thr806Ala)
c.2338A>G (p.Thr780Ala)
n.2858A>G
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882027A>TCA359786720MAP3K1c.2827A>T (p.Thr943Ser)
c.2449A>T (p.Thr817Ser)
c.2572A>T (p.Thr858Ser)
c.2548A>T (p.Thr850Ser)
c.2416A>T (p.Thr806Ser)
c.2338A>T (p.Thr780Ser)
n.2858A>T
5g.56882027_56882028delinsACCA1548139407MAP3K1c.2827_2828delinsAC (p.Thr943=)
c.2449_2450delinsAC (p.Thr817=)
c.2572_2573delinsAC (p.Thr858=)
c.2548_2549delinsAC (p.Thr850=)
c.2416_2417delinsAC (p.Thr806=)
c.2338_2339delinsAC (p.Thr780=)
n.2858_2859delinsAC
5g.56882031_56882032insTACAACCA2708985397MAP3K1c.2831_2832insTACAAC (p.Thr944_Thr945insThrThr)
c.2453_2454insTACAAC (p.Thr818_Thr819insThrThr)
c.2576_2577insTACAAC (p.Thr859_Thr860insThrThr)
c.2552_2553insTACAAC (p.Thr851_Thr852insThrThr)
c.2420_2421insTACAAC (p.Thr807_Thr808insThrThr)
c.2342_2343insTACAAC (p.Thr781_Thr782insThrThr)
n.2862_2863insTACAAC
 dbSNP
5g.56882028delCA3273071MAP3K1c.2828del (p.Thr943LysfsTer25)
c.2450del (p.Thr817LysfsTer25)
c.2573del (p.Thr858LysfsTer25)
c.2549del (p.Thr850LysfsTer25)
c.2417del (p.Thr806LysfsTer25)
c.2339del (p.Thr780LysfsTer25)
n.2859del
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882028C>ACA359786721MAP3K1c.2828C>A (p.Thr943Lys)
c.2450C>A (p.Thr817Lys)
c.2573C>A (p.Thr858Lys)
c.2549C>A (p.Thr850Lys)
c.2417C>A (p.Thr806Lys)
c.2339C>A (p.Thr780Lys)
n.2859C>A
5g.56882028C>GCA359786722MAP3K1c.2828C>G (p.Thr943Arg)
c.2450C>G (p.Thr817Arg)
c.2573C>G (p.Thr858Arg)
c.2549C>G (p.Thr850Arg)
c.2417C>G (p.Thr806Arg)
c.2339C>G (p.Thr780Arg)
n.2859C>G
5g.56882028C>TCA359786724MAP3K1c.2828C>T (p.Thr943Ile)
c.2450C>T (p.Thr817Ile)
c.2573C>T (p.Thr858Ile)
c.2549C>T (p.Thr850Ile)
c.2417C>T (p.Thr806Ile)
c.2339C>T (p.Thr780Ile)
n.2859C>T
5g.56882032_56882033insTCAACACA2708985399MAP3K1c.2832_2833insTCAACA (p.Thr944_Thr945insSerThr)
c.2454_2455insTCAACA (p.Thr818_Thr819insSerThr)
c.2577_2578insTCAACA (p.Thr859_Thr860insSerThr)
c.2553_2554insTCAACA (p.Thr851_Thr852insSerThr)
c.2421_2422insTCAACA (p.Thr807_Thr808insSerThr)
c.2343_2344insTCAACA (p.Thr781_Thr782insSerThr)
n.2863_2864insTCAACA
 dbSNP
5g.56882029A>CCA444399381MAP3K1c.2829A>C (p.Thr943=)
c.2451A>C (p.Thr817=)
c.2574A>C (p.Thr858=)
c.2550A>C (p.Thr850=)
c.2418A>C (p.Thr806=)
c.2340A>C (p.Thr780=)
n.2860A>C
5g.56882029A>GCA444399378MAP3K1c.2829A>G (p.Thr943=)
c.2451A>G (p.Thr817=)
c.2574A>G (p.Thr858=)
c.2550A>G (p.Thr850=)
c.2418A>G (p.Thr806=)
c.2340A>G (p.Thr780=)
n.2860A>G
 gnomAD v4
5g.56882029A>TCA444399380MAP3K1c.2829A>T (p.Thr943=)
c.2451A>T (p.Thr817=)
c.2574A>T (p.Thr858=)
c.2550A>T (p.Thr850=)
c.2418A>T (p.Thr806=)
c.2340A>T (p.Thr780=)
n.2860A>T
5g.56882029_56882031delinsAACCA1548139408MAP3K1c.2829_2831delinsAAC (p.Thr943=)
c.2451_2453delinsAAC (p.Thr817=)
c.2574_2576delinsAAC (p.Thr858=)
c.2550_2552delinsAAC (p.Thr850=)
c.2418_2420delinsAAC (p.Thr806=)
c.2340_2342delinsAAC (p.Thr780=)
n.2860_2862delinsAAC
5g.56882030A=CA1548139409MAP3K1c.2830A= (p.Thr944=)
c.2452A= (p.Thr818=)
c.2575A= (p.Thr859=)
c.2551A= (p.Thr851=)
c.2419A= (p.Thr807=)
c.2341A= (p.Thr781=)
n.2861A=
5g.56882030A>CCA359786728MAP3K1c.2830A>C (p.Thr944Pro)
c.2452A>C (p.Thr818Pro)
c.2575A>C (p.Thr859Pro)
c.2551A>C (p.Thr851Pro)
c.2419A>C (p.Thr807Pro)
c.2341A>C (p.Thr781Pro)
n.2861A>C
5g.56882030A>GCA3273074MAP3K1c.2830A>G (p.Thr944Ala)
c.2452A>G (p.Thr818Ala)
c.2575A>G (p.Thr859Ala)
c.2551A>G (p.Thr851Ala)
c.2419A>G (p.Thr807Ala)
c.2341A>G (p.Thr781Ala)
n.2861A>G
 dbSNP ExAC gnomAD v2 gnomAD v4
5g.56882030A>TCA359786731MAP3K1c.2830A>T (p.Thr944Ser)
c.2452A>T (p.Thr818Ser)
c.2575A>T (p.Thr859Ser)
c.2551A>T (p.Thr851Ser)
c.2419A>T (p.Thr807Ser)
c.2341A>T (p.Thr781Ser)
n.2861A>T
5g.56882031_56882032dupCA917480356MAP3K1c.2831_2832dup (p.Thr945GlnfsTer24)
c.2453_2454dup (p.Thr819GlnfsTer24)
c.2576_2577dup (p.Thr860GlnfsTer24)
c.2552_2553dup (p.Thr852GlnfsTer24)
c.2420_2421dup (p.Thr808GlnfsTer24)
c.2342_2343dup (p.Thr782GlnfsTer24)
n.2862_2863dup
 dbSNP
5g.56882031_56882032delCA3273073MAP3K1c.2831_2832del (p.Thr944AsnfsTer?)
c.2453_2454del (p.Thr818AsnfsTer?)
c.2576_2577del (p.Thr859AsnfsTer?)
c.2552_2553del (p.Thr851AsnfsTer?)
c.2420_2421del (p.Thr807AsnfsTer?)
c.2342_2343del (p.Thr781AsnfsTer?)
n.2862_2863del
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882031_56882047delCA2766565561MAP3K1c.2831_2847del (p.Thr944ArgfsTer?)
c.2453_2469del (p.Thr818ArgfsTer?)
c.2576_2592del (p.Thr859ArgfsTer?)
c.2552_2568del (p.Thr851ArgfsTer?)
c.2420_2436del (p.Thr807ArgfsTer?)
c.2342_2358del (p.Thr781ArgfsTer?)
n.2862_2878del
5g.56882031C>ACA359786736MAP3K1c.2831C>A (p.Thr944Lys)
c.2453C>A (p.Thr818Lys)
c.2576C>A (p.Thr859Lys)
c.2552C>A (p.Thr851Lys)
c.2420C>A (p.Thr807Lys)
c.2342C>A (p.Thr781Lys)
n.2862C>A
 dbSNP
5g.56882031C=CA1548139410MAP3K1c.2831C= (p.Thr944=)
c.2453C= (p.Thr818=)
c.2576C= (p.Thr859=)
c.2552C= (p.Thr851=)
c.2420C= (p.Thr807=)
c.2342C= (p.Thr781=)
n.2862C=
5g.56882031C>GCA359786738MAP3K1c.2831C>G (p.Thr944Arg)
c.2453C>G (p.Thr818Arg)
c.2576C>G (p.Thr859Arg)
c.2552C>G (p.Thr851Arg)
c.2420C>G (p.Thr807Arg)
c.2342C>G (p.Thr781Arg)
n.2862C>G
5g.56882031C>TCA119079654MAP3K1c.2831C>T (p.Thr944Ile)
c.2453C>T (p.Thr818Ile)
c.2576C>T (p.Thr859Ile)
c.2552C>T (p.Thr851Ile)
c.2420C>T (p.Thr807Ile)
c.2342C>T (p.Thr781Ile)
n.2862C>T
 dbSNP gnomAD v2
5g.56882031_56882032delinsCACA1548139411MAP3K1c.2831_2832delinsCA (p.Thr944=)
c.2453_2454delinsCA (p.Thr818=)
c.2576_2577delinsCA (p.Thr859=)
c.2552_2553delinsCA (p.Thr851=)
c.2420_2421delinsCA (p.Thr807=)
c.2342_2343delinsCA (p.Thr781=)
n.2862_2863delinsCA
5g.56882035_56882036insCCAACACA2708985401MAP3K1c.2835_2836insCCAACA (p.Thr945_Thr946insProThr)
c.2457_2458insCCAACA (p.Thr819_Thr820insProThr)
c.2580_2581insCCAACA (p.Thr860_Thr861insProThr)
c.2556_2557insCCAACA (p.Thr852_Thr853insProThr)
c.2424_2425insCCAACA (p.Thr808_Thr809insProThr)
c.2346_2347insCCAACA (p.Thr782_Thr783insProThr)
n.2866_2867insCCAACA
 dbSNP
5g.56882032A>CCA444399384MAP3K1c.2832A>C (p.Thr944=)
c.2454A>C (p.Thr818=)
c.2577A>C (p.Thr859=)
c.2553A>C (p.Thr851=)
c.2421A>C (p.Thr807=)
c.2343A>C (p.Thr781=)
n.2863A>C
5g.56882032A>GCA444399387MAP3K1c.2832A>G (p.Thr944=)
c.2454A>G (p.Thr818=)
c.2577A>G (p.Thr859=)
c.2553A>G (p.Thr851=)
c.2421A>G (p.Thr807=)
c.2343A>G (p.Thr781=)
n.2863A>G
5g.56882032A>TCA444399385MAP3K1c.2832A>T (p.Thr944=)
c.2454A>T (p.Thr818=)
c.2577A>T (p.Thr859=)
c.2553A>T (p.Thr851=)
c.2421A>T (p.Thr807=)
c.2343A>T (p.Thr781=)
n.2863A>T
5g.56882033delCA917480357MAP3K1c.2833del (p.Thr945GlnfsTer23)
c.2455del (p.Thr819GlnfsTer23)
c.2578del (p.Thr860GlnfsTer23)
c.2554del (p.Thr852GlnfsTer23)
c.2422del (p.Thr808GlnfsTer23)
c.2344del (p.Thr782GlnfsTer23)
n.2864del
 dbSNP
5g.56882033A>CCA359786741MAP3K1c.2833A>C (p.Thr945Pro)
c.2455A>C (p.Thr819Pro)
c.2578A>C (p.Thr860Pro)
c.2554A>C (p.Thr852Pro)
c.2422A>C (p.Thr808Pro)
c.2344A>C (p.Thr782Pro)
n.2864A>C
5g.56882033A>GCA359786745MAP3K1c.2833A>G (p.Thr945Ala)
c.2455A>G (p.Thr819Ala)
c.2578A>G (p.Thr860Ala)
c.2554A>G (p.Thr852Ala)
c.2422A>G (p.Thr808Ala)
c.2344A>G (p.Thr782Ala)
n.2864A>G
5g.56882033A>TCA359786743MAP3K1c.2833A>T (p.Thr945Ser)
c.2455A>T (p.Thr819Ser)
c.2578A>T (p.Thr860Ser)
c.2554A>T (p.Thr852Ser)
c.2422A>T (p.Thr808Ser)
c.2344A>T (p.Thr782Ser)
n.2864A>T
5g.56882034C>ACA359786748MAP3K1c.2834C>A (p.Thr945Lys)
c.2456C>A (p.Thr819Lys)
c.2579C>A (p.Thr860Lys)
c.2555C>A (p.Thr852Lys)
c.2423C>A (p.Thr808Lys)
c.2345C>A (p.Thr782Lys)
n.2865C>A
 dbSNP
5g.56882034C=CA1548139412MAP3K1c.2834C= (p.Thr945=)
c.2456C= (p.Thr819=)
c.2579C= (p.Thr860=)
c.2555C= (p.Thr852=)
c.2423C= (p.Thr808=)
c.2345C= (p.Thr782=)
n.2865C=
5g.56882034C>GCA359786751MAP3K1c.2834C>G (p.Thr945Arg)
c.2456C>G (p.Thr819Arg)
c.2579C>G (p.Thr860Arg)
c.2555C>G (p.Thr852Arg)
c.2423C>G (p.Thr808Arg)
c.2345C>G (p.Thr782Arg)
n.2865C>G
5g.56882034C>TCA359786753MAP3K1c.2834C>T (p.Thr945Ile)
c.2456C>T (p.Thr819Ile)
c.2579C>T (p.Thr860Ile)
c.2555C>T (p.Thr852Ile)
c.2423C>T (p.Thr808Ile)
c.2345C>T (p.Thr782Ile)
n.2865C>T
5g.56882035A>CCA444399388MAP3K1c.2835A>C (p.Thr945=)
c.2457A>C (p.Thr819=)
c.2580A>C (p.Thr860=)
c.2556A>C (p.Thr852=)
c.2424A>C (p.Thr808=)
c.2346A>C (p.Thr782=)
n.2866A>C
5g.56882035A>GCA444399389MAP3K1c.2835A>G (p.Thr945=)
c.2457A>G (p.Thr819=)
c.2580A>G (p.Thr860=)
c.2556A>G (p.Thr852=)
c.2424A>G (p.Thr808=)
c.2346A>G (p.Thr782=)
n.2866A>G
 gnomAD v4
5g.56882035A>TCA444399390MAP3K1c.2835A>T (p.Thr945=)
c.2457A>T (p.Thr819=)
c.2580A>T (p.Thr860=)
c.2556A>T (p.Thr852=)
c.2424A>T (p.Thr808=)
c.2346A>T (p.Thr782=)
n.2866A>T
5g.56882036A=CA1548139413MAP3K1c.2836A= (p.Thr946=)
c.2458A= (p.Thr820=)
c.2581A= (p.Thr861=)
c.2557A= (p.Thr853=)
c.2425A= (p.Thr809=)
c.2347A= (p.Thr783=)
n.2867A=
5g.56882036A>CCA359786755MAP3K1c.2836A>C (p.Thr946Pro)
c.2458A>C (p.Thr820Pro)
c.2581A>C (p.Thr861Pro)
c.2557A>C (p.Thr853Pro)
c.2425A>C (p.Thr809Pro)
c.2347A>C (p.Thr783Pro)
n.2867A>C
5g.56882036A>GCA359786757MAP3K1c.2836A>G (p.Thr946Ala)
c.2458A>G (p.Thr820Ala)
c.2581A>G (p.Thr861Ala)
c.2557A>G (p.Thr853Ala)
c.2425A>G (p.Thr809Ala)
c.2347A>G (p.Thr783Ala)
n.2867A>G
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56882036A>TCA359786759MAP3K1c.2836A>T (p.Thr946Ser)
c.2458A>T (p.Thr820Ser)
c.2581A>T (p.Thr861Ser)
c.2557A>T (p.Thr853Ser)
c.2425A>T (p.Thr809Ser)
c.2347A>T (p.Thr783Ser)
n.2867A>T
5g.56882037C>ACA359786760MAP3K1c.2837C>A (p.Thr946Lys)
c.2459C>A (p.Thr820Lys)
c.2582C>A (p.Thr861Lys)
c.2558C>A (p.Thr853Lys)
c.2426C>A (p.Thr809Lys)
c.2348C>A (p.Thr783Lys)
n.2868C>A
5g.56882037C=CA1548139414MAP3K1c.2837C= (p.Thr946=)
c.2459C= (p.Thr820=)
c.2582C= (p.Thr861=)
c.2558C= (p.Thr853=)
c.2426C= (p.Thr809=)
c.2348C= (p.Thr783=)
n.2868C=
5g.56882037C>GCA359786762MAP3K1c.2837C>G (p.Thr946Arg)
c.2459C>G (p.Thr820Arg)
c.2582C>G (p.Thr861Arg)
c.2558C>G (p.Thr853Arg)
c.2426C>G (p.Thr809Arg)
c.2348C>G (p.Thr783Arg)
n.2868C>G
5g.56882037C>TCA3273075MAP3K1c.2837C>T (p.Thr946Ile)
c.2459C>T (p.Thr820Ile)
c.2582C>T (p.Thr861Ile)
c.2558C>T (p.Thr853Ile)
c.2426C>T (p.Thr809Ile)
c.2348C>T (p.Thr783Ile)
n.2868C>T
 dbSNP ExAC gnomAD v2
5g.56882038A>CCA444399394MAP3K1c.2838A>C (p.Thr946=)
c.2460A>C (p.Thr820=)
c.2583A>C (p.Thr861=)
c.2559A>C (p.Thr853=)
c.2427A>C (p.Thr809=)
c.2349A>C (p.Thr783=)
n.2869A>C
5g.56882038A>GCA444399396MAP3K1c.2838A>G (p.Thr946=)
c.2460A>G (p.Thr820=)
c.2583A>G (p.Thr861=)
c.2559A>G (p.Thr853=)
c.2427A>G (p.Thr809=)
c.2349A>G (p.Thr783=)
n.2869A>G
 gnomAD v4
5g.56882038A>TCA444399395MAP3K1c.2838A>T (p.Thr946=)
c.2460A>T (p.Thr820=)
c.2583A>T (p.Thr861=)
c.2559A>T (p.Thr853=)
c.2427A>T (p.Thr809=)
c.2349A>T (p.Thr783=)
n.2869A>T
5g.56882039A=CA1548139415MAP3K1c.2839A= (p.Thr947=)
c.2461A= (p.Thr821=)
c.2584A= (p.Thr862=)
c.2560A= (p.Thr854=)
c.2428A= (p.Thr810=)
c.2350A= (p.Thr784=)
n.2870A=
5g.56882039A>CCA359786764MAP3K1c.2839A>C (p.Thr947Pro)
c.2461A>C (p.Thr821Pro)
c.2584A>C (p.Thr862Pro)
c.2560A>C (p.Thr854Pro)
c.2428A>C (p.Thr810Pro)
c.2350A>C (p.Thr784Pro)
n.2870A>C
5g.56882039A>GCA119079667MAP3K1c.2839A>G (p.Thr947Ala)
c.2461A>G (p.Thr821Ala)
c.2584A>G (p.Thr862Ala)
c.2560A>G (p.Thr854Ala)
c.2428A>G (p.Thr810Ala)
c.2350A>G (p.Thr784Ala)
n.2870A>G
 dbSNP gnomAD v4
5g.56882039A>TCA359786766MAP3K1c.2839A>T (p.Thr947Ser)
c.2461A>T (p.Thr821Ser)
c.2584A>T (p.Thr862Ser)
c.2560A>T (p.Thr854Ser)
c.2428A>T (p.Thr810Ser)
c.2350A>T (p.Thr784Ser)
n.2870A>T
5g.56882039_56882040delinsACCA1548139416MAP3K1c.2839_2840delinsAC (p.Thr947=)
c.2461_2462delinsAC (p.Thr821=)
c.2584_2585delinsAC (p.Thr862=)
c.2560_2561delinsAC (p.Thr854=)
c.2428_2429delinsAC (p.Thr810=)
c.2350_2351delinsAC (p.Thr784=)
n.2870_2871delinsAC
5g.56882040delCA559801261MAP3K1c.2840del (p.Thr947LysfsTer21)
c.2462del (p.Thr821LysfsTer21)
c.2585del (p.Thr862LysfsTer21)
c.2561del (p.Thr854LysfsTer21)
c.2429del (p.Thr810LysfsTer21)
c.2351del (p.Thr784LysfsTer21)
n.2871del
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56882040C>ACA359786770MAP3K1c.2840C>A (p.Thr947Lys)
c.2462C>A (p.Thr821Lys)
c.2585C>A (p.Thr862Lys)
c.2561C>A (p.Thr854Lys)
c.2429C>A (p.Thr810Lys)
c.2351C>A (p.Thr784Lys)
n.2871C>A
5g.56882040C>GCA359786772MAP3K1c.2840C>G (p.Thr947Arg)
c.2462C>G (p.Thr821Arg)
c.2585C>G (p.Thr862Arg)
c.2561C>G (p.Thr854Arg)
c.2429C>G (p.Thr810Arg)
c.2351C>G (p.Thr784Arg)
n.2871C>G
5g.56882040C>TCA359786769MAP3K1c.2840C>T (p.Thr947Ile)
c.2462C>T (p.Thr821Ile)
c.2585C>T (p.Thr862Ile)
c.2561C>T (p.Thr854Ile)
c.2429C>T (p.Thr810Ile)
c.2351C>T (p.Thr784Ile)
n.2871C>T
5g.56882040_56882042delinsCAACA1548139417MAP3K1c.2840_2842delinsCAA (p.Thr947=)
c.2462_2464delinsCAA (p.Thr821=)
c.2585_2587delinsCAA (p.Thr862=)
c.2561_2563delinsCAA (p.Thr854=)
c.2429_2431delinsCAA (p.Thr810=)
c.2351_2353delinsCAA (p.Thr784=)
n.2871_2873delinsCAA
5g.56882044_56882045insTCAACACA2708985416MAP3K1c.2844_2845insTCAACA (p.Thr948_Thr949insSerThr)
c.2466_2467insTCAACA (p.Thr822_Thr823insSerThr)
c.2589_2590insTCAACA (p.Thr863_Thr864insSerThr)
c.2565_2566insTCAACA (p.Thr855_Thr856insSerThr)
c.2433_2434insTCAACA (p.Thr811_Thr812insSerThr)
c.2355_2356insTCAACA (p.Thr785_Thr786insSerThr)
n.2875_2876insTCAACA
 dbSNP
5g.56882041A=CA1548139418MAP3K1c.2841A= (p.Thr947=)
c.2463A= (p.Thr821=)
c.2586A= (p.Thr862=)
c.2562A= (p.Thr854=)
c.2430A= (p.Thr810=)
c.2352A= (p.Thr784=)
n.2872A=
5g.56882041A>CCA444399398MAP3K1c.2841A>C (p.Thr947=)
c.2463A>C (p.Thr821=)
c.2586A>C (p.Thr862=)
c.2562A>C (p.Thr854=)
c.2430A>C (p.Thr810=)
c.2352A>C (p.Thr784=)
n.2872A>C
5g.56882041A>GCA444399401MAP3K1c.2841A>G (p.Thr947=)
c.2463A>G (p.Thr821=)
c.2586A>G (p.Thr862=)
c.2562A>G (p.Thr854=)
c.2430A>G (p.Thr810=)
c.2352A>G (p.Thr784=)
n.2872A>G
 dbSNP gnomAD v4
5g.56882041A>TCA444399402MAP3K1c.2841A>T (p.Thr947=)
c.2463A>T (p.Thr821=)
c.2586A>T (p.Thr862=)
c.2562A>T (p.Thr854=)
c.2430A>T (p.Thr810=)
c.2352A>T (p.Thr784=)
n.2872A>T
5g.56882041_56882042delCA119079680MAP3K1c.2841_2842del (p.Thr948AsnfsTer?)
c.2463_2464del (p.Thr822AsnfsTer?)
c.2586_2587del (p.Thr863AsnfsTer?)
c.2562_2563del (p.Thr855AsnfsTer?)
c.2430_2431del (p.Thr811AsnfsTer?)
c.2352_2353del (p.Thr785AsnfsTer?)
n.2872_2873del
 dbSNP
5g.56882041_56882043delinsAACCA1548139419MAP3K1c.2841_2843delinsAAC (p.Thr947=)
c.2463_2465delinsAAC (p.Thr821=)
c.2586_2588delinsAAC (p.Thr862=)
c.2562_2564delinsAAC (p.Thr854=)
c.2430_2432delinsAAC (p.Thr810=)
c.2352_2354delinsAAC (p.Thr784=)
n.2872_2874delinsAAC
5g.56882042A=CA1548139420MAP3K1c.2842A= (p.Thr948=)
c.2464A= (p.Thr822=)
c.2587A= (p.Thr863=)
c.2563A= (p.Thr855=)
c.2431A= (p.Thr811=)
c.2353A= (p.Thr785=)
n.2873A=
5g.56882042A>CCA359786777MAP3K1c.2842A>C (p.Thr948Pro)
c.2464A>C (p.Thr822Pro)
c.2587A>C (p.Thr863Pro)
c.2563A>C (p.Thr855Pro)
c.2431A>C (p.Thr811Pro)
c.2353A>C (p.Thr785Pro)
n.2873A>C
5g.56882042A>GCA359786775MAP3K1c.2842A>G (p.Thr948Ala)
c.2464A>G (p.Thr822Ala)
c.2587A>G (p.Thr863Ala)
c.2563A>G (p.Thr855Ala)
c.2431A>G (p.Thr811Ala)
c.2353A>G (p.Thr785Ala)
n.2873A>G
 dbSNP gnomAD v4
5g.56882042A>TCA359786779MAP3K1c.2842A>T (p.Thr948Ser)
c.2464A>T (p.Thr822Ser)
c.2587A>T (p.Thr863Ser)
c.2563A>T (p.Thr855Ser)
c.2431A>T (p.Thr811Ser)
c.2353A>T (p.Thr785Ser)
n.2873A>T
5g.56882043_56882044delCA559801262MAP3K1c.2843_2844del (p.Thr948AsnfsTer?)
c.2465_2466del (p.Thr822AsnfsTer?)
c.2588_2589del (p.Thr863AsnfsTer?)
c.2564_2565del (p.Thr855AsnfsTer?)
c.2432_2433del (p.Thr811AsnfsTer?)
c.2354_2355del (p.Thr785AsnfsTer?)
n.2874_2875del
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56882043C>ACA119079685MAP3K1c.2843C>A (p.Thr948Lys)
c.2465C>A (p.Thr822Lys)
c.2588C>A (p.Thr863Lys)
c.2564C>A (p.Thr855Lys)
c.2432C>A (p.Thr811Lys)
c.2354C>A (p.Thr785Lys)
n.2874C>A
 dbSNP gnomAD v2
5g.56882043C=CA1548139422MAP3K1c.2843C= (p.Thr948=)
c.2465C= (p.Thr822=)
c.2588C= (p.Thr863=)
c.2564C= (p.Thr855=)
c.2432C= (p.Thr811=)
c.2354C= (p.Thr785=)
n.2874C=
5g.56882043C>GCA359786781MAP3K1c.2843C>G (p.Thr948Arg)
c.2465C>G (p.Thr822Arg)
c.2588C>G (p.Thr863Arg)
c.2564C>G (p.Thr855Arg)
c.2432C>G (p.Thr811Arg)
c.2354C>G (p.Thr785Arg)
n.2874C>G
 gnomAD v4
5g.56882043C>TCA359786783MAP3K1c.2843C>T (p.Thr948Ile)
c.2465C>T (p.Thr822Ile)
c.2588C>T (p.Thr863Ile)
c.2564C>T (p.Thr855Ile)
c.2432C>T (p.Thr811Ile)
c.2354C>T (p.Thr785Ile)
n.2874C>T
5g.56882043_56882044delinsCACA1548139421MAP3K1c.2843_2844delinsCA (p.Thr948=)
c.2465_2466delinsCA (p.Thr822=)
c.2588_2589delinsCA (p.Thr863=)
c.2564_2565delinsCA (p.Thr855=)
c.2432_2433delinsCA (p.Thr811=)
c.2354_2355delinsCA (p.Thr785=)
n.2874_2875delinsCA
5g.56882043_56882045delinsCAACA1548139423MAP3K1c.2843_2845delinsCAA (p.Thr948=)
c.2465_2467delinsCAA (p.Thr822=)
c.2588_2590delinsCAA (p.Thr863=)
c.2564_2566delinsCAA (p.Thr855=)
c.2432_2434delinsCAA (p.Thr811=)
c.2354_2356delinsCAA (p.Thr785=)
n.2874_2876delinsCAA
5g.56882043_56882048delCA2673909980MAP3K1c.2843_2848del (p.Thr948_Glu950delinsLys)
c.2465_2470del (p.Thr822_Glu824delinsLys)
c.2588_2593del (p.Thr863_Glu865delinsLys)
c.2564_2569del (p.Thr855_Glu857delinsLys)
c.2432_2437del (p.Thr811_Glu813delinsLys)
c.2354_2359del (p.Thr785_Glu787delinsLys)
n.2874_2879del
 gnomAD v4
5g.56882044A=CA1548139424MAP3K1c.2844A= (p.Thr948=)
c.2466A= (p.Thr822=)
c.2589A= (p.Thr863=)
c.2565A= (p.Thr855=)
c.2433A= (p.Thr811=)
c.2355A= (p.Thr785=)
n.2875A=
5g.56882044A>CCA444399404MAP3K1c.2844A>C (p.Thr948=)
c.2466A>C (p.Thr822=)
c.2589A>C (p.Thr863=)
c.2565A>C (p.Thr855=)
c.2433A>C (p.Thr811=)
c.2355A>C (p.Thr785=)
n.2875A>C
5g.56882044A>GCA444399406MAP3K1c.2844A>G (p.Thr948=)
c.2466A>G (p.Thr822=)
c.2589A>G (p.Thr863=)
c.2565A>G (p.Thr855=)
c.2433A>G (p.Thr811=)
c.2355A>G (p.Thr785=)
n.2875A>G
5g.56882044A>TCA444399407MAP3K1c.2844A>T (p.Thr948=)
c.2466A>T (p.Thr822=)
c.2589A>T (p.Thr863=)
c.2565A>T (p.Thr855=)
c.2433A>T (p.Thr811=)
c.2355A>T (p.Thr785=)
n.2875A>T
5g.56882044_56882045delCA559801263MAP3K1c.2844_2845del (p.Thr949ArgfsTer?)
c.2466_2467del (p.Thr823ArgfsTer?)
c.2589_2590del (p.Thr864ArgfsTer?)
c.2565_2566del (p.Thr856ArgfsTer?)
c.2433_2434del (p.Thr812ArgfsTer?)
c.2355_2356del (p.Thr786ArgfsTer?)
n.2875_2876del
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56882045delCA917480358MAP3K1c.2845del (p.Thr949GlnfsTer19)
c.2467del (p.Thr823GlnfsTer19)
c.2590del (p.Thr864GlnfsTer19)
c.2566del (p.Thr856GlnfsTer19)
c.2434del (p.Thr812GlnfsTer19)
c.2356del (p.Thr786GlnfsTer19)
n.2876del
 dbSNP
5g.56882045A>CCA359786785MAP3K1c.2845A>C (p.Thr949Pro)
c.2467A>C (p.Thr823Pro)
c.2590A>C (p.Thr864Pro)
c.2566A>C (p.Thr856Pro)
c.2434A>C (p.Thr812Pro)
c.2356A>C (p.Thr786Pro)
n.2876A>C
5g.56882045A>GCA359786786MAP3K1c.2845A>G (p.Thr949Ala)
c.2467A>G (p.Thr823Ala)
c.2590A>G (p.Thr864Ala)
c.2566A>G (p.Thr856Ala)
c.2434A>G (p.Thr812Ala)
c.2356A>G (p.Thr786Ala)
n.2876A>G
5g.56882045A>TCA359786788MAP3K1c.2845A>T (p.Thr949Ser)
c.2467A>T (p.Thr823Ser)
c.2590A>T (p.Thr864Ser)
c.2566A>T (p.Thr856Ser)
c.2434A>T (p.Thr812Ser)
c.2356A>T (p.Thr786Ser)
n.2876A>T
5g.56882046_56882047dupCA917480360MAP3K1c.2846_2847dup (p.Glu950GlnfsTer19)
c.2468_2469dup (p.Glu824GlnfsTer19)
c.2591_2592dup (p.Glu865GlnfsTer19)
c.2567_2568dup (p.Glu857GlnfsTer19)
c.2435_2436dup (p.Glu813GlnfsTer19)
c.2357_2358dup (p.Glu787GlnfsTer19)
n.2877_2878dup
 dbSNP
5g.56882046C>ACA359786791MAP3K1c.2846C>A (p.Thr949Lys)
c.2468C>A (p.Thr823Lys)
c.2591C>A (p.Thr864Lys)
c.2567C>A (p.Thr856Lys)
c.2435C>A (p.Thr812Lys)
c.2357C>A (p.Thr786Lys)
n.2877C>A
 dbSNP
5g.56882046C>GCA359786793MAP3K1c.2846C>G (p.Thr949Arg)
c.2468C>G (p.Thr823Arg)
c.2591C>G (p.Thr864Arg)
c.2567C>G (p.Thr856Arg)
c.2435C>G (p.Thr812Arg)
c.2357C>G (p.Thr786Arg)
n.2877C>G
5g.56882046C>TCA359786795MAP3K1c.2846C>T (p.Thr949Ile)
c.2468C>T (p.Thr823Ile)
c.2591C>T (p.Thr864Ile)
c.2567C>T (p.Thr856Ile)
c.2435C>T (p.Thr812Ile)
c.2357C>T (p.Thr786Ile)
n.2877C>T
 gnomAD v4
5g.56882046_56882047delinsCACA1548139425MAP3K1c.2846_2847delinsCA (p.Thr949=)
c.2468_2469delinsCA (p.Thr823=)
c.2591_2592delinsCA (p.Thr864=)
c.2567_2568delinsCA (p.Thr856=)
c.2435_2436delinsCA (p.Thr812=)
c.2357_2358delinsCA (p.Thr786=)
n.2877_2878delinsCA
5g.56882046_56882048delCA2708985477MAP3K1c.2846_2848del (p.Thr949_Glu950delinsLys)
c.2468_2470del (p.Thr823_Glu824delinsLys)
c.2591_2593del (p.Thr864_Glu865delinsLys)
c.2567_2569del (p.Thr856_Glu857delinsLys)
c.2435_2437del (p.Thr812_Glu813delinsLys)
c.2357_2359del (p.Thr786_Glu787delinsLys)
n.2877_2879del
 dbSNP
5g.56882047delCA559801264MAP3K1c.2847del (p.Glu950SerfsTer18)
c.2469del (p.Glu824SerfsTer18)
c.2592del (p.Glu865SerfsTer18)
c.2568del (p.Glu857SerfsTer18)
c.2436del (p.Glu813SerfsTer18)
c.2358del (p.Glu787SerfsTer18)
n.2878del
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
5g.56882047A=CA1548139426MAP3K1c.2847A= (p.Thr949=)
c.2469A= (p.Thr823=)
c.2592A= (p.Thr864=)
c.2568A= (p.Thr856=)
c.2436A= (p.Thr812=)
c.2358A= (p.Thr786=)
n.2878A=
5g.56882047A>CCA444399409MAP3K1c.2847A>C (p.Thr949=)
c.2469A>C (p.Thr823=)
c.2592A>C (p.Thr864=)
c.2568A>C (p.Thr856=)
c.2436A>C (p.Thr812=)
c.2358A>C (p.Thr786=)
n.2878A>C
 dbSNP
5g.56882047A>GCA444399410MAP3K1c.2847A>G (p.Thr949=)
c.2469A>G (p.Thr823=)
c.2592A>G (p.Thr864=)
c.2568A>G (p.Thr856=)
c.2436A>G (p.Thr812=)
c.2358A>G (p.Thr786=)
n.2878A>G
5g.56882047A>TCA444399411MAP3K1c.2847A>T (p.Thr949=)
c.2469A>T (p.Thr823=)
c.2592A>T (p.Thr864=)
c.2568A>T (p.Thr856=)
c.2436A>T (p.Thr812=)
c.2358A>T (p.Thr786=)
n.2878A>T
5g.56882047_56882048insACAACAAAACA2708985507MAP3K1c.2847_2848insACAACAAAA (p.Thr949_Glu950insThrThrLys)
c.2469_2470insACAACAAAA (p.Thr823_Glu824insThrThrLys)
c.2592_2593insACAACAAAA (p.Thr864_Glu865insThrThrLys)
c.2568_2569insACAACAAAA (p.Thr856_Glu857insThrThrLys)
c.2436_2437insACAACAAAA (p.Thr812_Glu813insThrThrLys)
c.2358_2359insACAACAAAA (p.Thr786_Glu787insThrThrLys)
n.2878_2879insACAACAAAA
 dbSNP
5g.56882049_56882050delCA645557017MAP3K1c.2849_2850del (p.Glu950AlafsTer?)
c.2471_2472del (p.Glu824AlafsTer?)
c.2594_2595del (p.Glu865AlafsTer?)
c.2570_2571del (p.Glu857AlafsTer?)
c.2438_2439del (p.Glu813AlafsTer?)
c.2360_2361del (p.Glu787AlafsTer?)
n.2880_2881del
 COSMIC
5g.56882048G>ACA359786797MAP3K1c.2848G>A (p.Glu950Lys)
c.2470G>A (p.Glu824Lys)
c.2593G>A (p.Glu865Lys)
c.2569G>A (p.Glu857Lys)
c.2437G>A (p.Glu813Lys)
c.2359G>A (p.Glu787Lys)
n.2879G>A
 dbSNP
5g.56882048G>CCA359786799MAP3K1c.2848G>C (p.Glu950Gln)
c.2470G>C (p.Glu824Gln)
c.2593G>C (p.Glu865Gln)
c.2569G>C (p.Glu857Gln)
c.2437G>C (p.Glu813Gln)
c.2359G>C (p.Glu787Gln)
n.2879G>C
 dbSNP gnomAD v4
5g.56882048G>TCA359786800MAP3K1c.2848G>T (p.Glu950Ter)
c.2470G>T (p.Glu824Ter)
c.2593G>T (p.Glu865Ter)
c.2569G>T (p.Glu857Ter)
c.2437G>T (p.Glu813Ter)
c.2359G>T (p.Glu787Ter)
n.2879G>T
5g.56882049A=CA1548139427MAP3K1c.2849A= (p.Glu950=)
c.2471A= (p.Glu824=)
c.2594A= (p.Glu865=)
c.2570A= (p.Glu857=)
c.2438A= (p.Glu813=)
c.2360A= (p.Glu787=)
n.2880A=
5g.56882049A>CCA359786807MAP3K1c.2849A>C (p.Glu950Ala)
c.2471A>C (p.Glu824Ala)
c.2594A>C (p.Glu865Ala)
c.2570A>C (p.Glu857Ala)
c.2438A>C (p.Glu813Ala)
c.2360A>C (p.Glu787Ala)
n.2880A>C
5g.56882049A>GCA359786803MAP3K1c.2849A>G (p.Glu950Gly)
c.2471A>G (p.Glu824Gly)
c.2594A>G (p.Glu865Gly)
c.2570A>G (p.Glu857Gly)
c.2438A>G (p.Glu813Gly)
c.2360A>G (p.Glu787Gly)
n.2880A>G
 dbSNP gnomAD v4
5g.56882049A>TCA359786805MAP3K1c.2849A>T (p.Glu950Val)
c.2471A>T (p.Glu824Val)
c.2594A>T (p.Glu865Val)
c.2570A>T (p.Glu857Val)
c.2438A>T (p.Glu813Val)
c.2360A>T (p.Glu787Val)
n.2880A>T
5g.56882050G>ACA3273076MAP3K1c.2850G>A (p.Glu950=)
c.2472G>A (p.Glu824=)
c.2595G>A (p.Glu865=)
c.2571G>A (p.Glu857=)
c.2439G>A (p.Glu813=)
c.2361G>A (p.Glu787=)
n.2881G>A
 dbSNP ExAC gnomAD v2 gnomAD v4
5g.56882050G>CCA359786810MAP3K1c.2850G>C (p.Glu950Asp)
c.2472G>C (p.Glu824Asp)
c.2595G>C (p.Glu865Asp)
c.2571G>C (p.Glu857Asp)
c.2439G>C (p.Glu813Asp)
c.2361G>C (p.Glu787Asp)
n.2881G>C
 dbSNP
5g.56882050G=CA1548139428MAP3K1c.2850G= (p.Glu950=)
c.2472G= (p.Glu824=)
c.2595G= (p.Glu865=)
c.2571G= (p.Glu857=)
c.2439G= (p.Glu813=)
c.2361G= (p.Glu787=)
n.2881G=
5g.56882050G>TCA359786812MAP3K1c.2850G>T (p.Glu950Asp)
c.2472G>T (p.Glu824Asp)
c.2595G>T (p.Glu865Asp)
c.2571G>T (p.Glu857Asp)
c.2439G>T (p.Glu813Asp)
c.2361G>T (p.Glu787Asp)
n.2881G>T
5g.56882051C>ACA359786815MAP3K1c.2851C>A (p.Gln951Lys)
c.2473C>A (p.Gln825Lys)
c.2596C>A (p.Gln866Lys)
c.2572C>A (p.Gln858Lys)
c.2440C>A (p.Gln814Lys)
c.2362C>A (p.Gln788Lys)
n.2882C>A
5g.56882051C>GCA359786817MAP3K1c.2851C>G (p.Gln951Glu)
c.2473C>G (p.Gln825Glu)
c.2596C>G (p.Gln866Glu)
c.2572C>G (p.Gln858Glu)
c.2440C>G (p.Gln814Glu)
c.2362C>G (p.Gln788Glu)
n.2882C>G
5g.56882051C>TCA359786819MAP3K1c.2851C>T (p.Gln951Ter)
c.2473C>T (p.Gln825Ter)
c.2596C>T (p.Gln866Ter)
c.2572C>T (p.Gln858Ter)
c.2440C>T (p.Gln814Ter)
c.2362C>T (p.Gln788Ter)
n.2882C>T
 dbSNP
5g.56882053_56882054insAAACAACA1548139429MAP3K1c.2853_2854insAAACAA (p.Gln951_Pro952insLysGln)
c.2475_2476insAAACAA (p.Gln825_Pro826insLysGln)
c.2598_2599insAAACAA (p.Gln866_Pro867insLysGln)
c.2574_2575insAAACAA (p.Gln858_Pro859insLysGln)
c.2442_2443insAAACAA (p.Gln814_Pro815insLysGln)
c.2364_2365insAAACAA (p.Gln788_Pro789insLysGln)
n.2884_2885insAAACAA
 dbSNP gnomAD v4
5g.56882052A>CCA359786821MAP3K1c.2852A>C (p.Gln951Pro)
c.2474A>C (p.Gln825Pro)
c.2597A>C (p.Gln866Pro)
c.2573A>C (p.Gln858Pro)
c.2441A>C (p.Gln814Pro)
c.2363A>C (p.Gln788Pro)
n.2883A>C
 dbSNP
5g.56882052A>GCA359786824MAP3K1c.2852A>G (p.Gln951Arg)
c.2474A>G (p.Gln825Arg)
c.2597A>G (p.Gln866Arg)
c.2573A>G (p.Gln858Arg)
c.2441A>G (p.Gln814Arg)
c.2363A>G (p.Gln788Arg)
n.2883A>G
5g.56882052A>TCA359786825MAP3K1c.2852A>T (p.Gln951Leu)
c.2474A>T (p.Gln825Leu)
c.2597A>T (p.Gln866Leu)
c.2573A>T (p.Gln858Leu)
c.2441A>T (p.Gln814Leu)
c.2363A>T (p.Gln788Leu)
n.2883A>T
5g.56882053A>CCA359786827MAP3K1c.2853A>C (p.Gln951His)
c.2475A>C (p.Gln825His)
c.2598A>C (p.Gln866His)
c.2574A>C (p.Gln858His)
c.2442A>C (p.Gln814His)
c.2364A>C (p.Gln788His)
n.2884A>C
5g.56882053A>GCA444399416MAP3K1c.2853A>G (p.Gln951=)
c.2475A>G (p.Gln825=)
c.2598A>G (p.Gln866=)
c.2574A>G (p.Gln858=)
c.2442A>G (p.Gln814=)
c.2364A>G (p.Gln788=)
n.2884A>G
 gnomAD v3 gnomAD v4
5g.56882053A>TCA359786829MAP3K1c.2853A>T (p.Gln951His)
c.2475A>T (p.Gln825His)
c.2598A>T (p.Gln866His)
c.2574A>T (p.Gln858His)
c.2442A>T (p.Gln814His)
c.2364A>T (p.Gln788His)
n.2884A>T
5g.56882054C>ACA359786836MAP3K1c.2854C>A (p.Pro952Thr)
c.2476C>A (p.Pro826Thr)
c.2599C>A (p.Pro867Thr)
c.2575C>A (p.Pro859Thr)
c.2443C>A (p.Pro815Thr)
c.2365C>A (p.Pro789Thr)
n.2885C>A
5g.56882054C>GCA359786833MAP3K1c.2854C>G (p.Pro952Ala)
c.2476C>G (p.Pro826Ala)
c.2599C>G (p.Pro867Ala)
c.2575C>G (p.Pro859Ala)
c.2443C>G (p.Pro815Ala)
c.2365C>G (p.Pro789Ala)
n.2885C>G
5g.56882054C>TCA359786831MAP3K1c.2854C>T (p.Pro952Ser)
c.2476C>T (p.Pro826Ser)
c.2599C>T (p.Pro867Ser)
c.2575C>T (p.Pro859Ser)
c.2443C>T (p.Pro815Ser)
c.2365C>T (p.Pro789Ser)
n.2885C>T
5g.56882055C>ACA359786840MAP3K1c.2855C>A (p.Pro952Gln)
c.2477C>A (p.Pro826Gln)
c.2600C>A (p.Pro867Gln)
c.2576C>A (p.Pro859Gln)
c.2444C>A (p.Pro815Gln)
c.2366C>A (p.Pro789Gln)
n.2886C>A
5g.56882055C=CA1548139430MAP3K1c.2855C= (p.Pro952=)
c.2477C= (p.Pro826=)
c.2600C= (p.Pro867=)
c.2576C= (p.Pro859=)
c.2444C= (p.Pro815=)
c.2366C= (p.Pro789=)
n.2886C=
5g.56882055C>GCA359786837MAP3K1c.2855C>G (p.Pro952Arg)
c.2477C>G (p.Pro826Arg)
c.2600C>G (p.Pro867Arg)
c.2576C>G (p.Pro859Arg)
c.2444C>G (p.Pro815Arg)
c.2366C>G (p.Pro789Arg)
n.2886C>G
 dbSNP gnomAD v2 gnomAD v4
5g.56882055C>TCA359786838MAP3K1c.2855C>T (p.Pro952Leu)
c.2477C>T (p.Pro826Leu)
c.2600C>T (p.Pro867Leu)
c.2576C>T (p.Pro859Leu)
c.2444C>T (p.Pro815Leu)
c.2366C>T (p.Pro789Leu)
n.2886C>T
5g.56882056A>CCA444399418MAP3K1c.2856A>C (p.Pro952=)
c.2478A>C (p.Pro826=)
c.2601A>C (p.Pro867=)
c.2577A>C (p.Pro859=)
c.2445A>C (p.Pro815=)
c.2367A>C (p.Pro789=)
n.2887A>C
5g.56882056A>GCA444399419MAP3K1c.2856A>G (p.Pro952=)
c.2478A>G (p.Pro826=)
c.2601A>G (p.Pro867=)
c.2577A>G (p.Pro859=)
c.2445A>G (p.Pro815=)
c.2367A>G (p.Pro789=)
n.2887A>G
5g.56882056A>TCA444399420MAP3K1c.2856A>T (p.Pro952=)
c.2478A>T (p.Pro826=)
c.2601A>T (p.Pro867=)
c.2577A>T (p.Pro859=)
c.2445A>T (p.Pro815=)
c.2367A>T (p.Pro789=)
n.2887A>T
5g.56882057A>CCA359786843MAP3K1c.2857A>C (p.Lys953Gln)
c.2479A>C (p.Lys827Gln)
c.2602A>C (p.Lys868Gln)
c.2578A>C (p.Lys860Gln)
c.2446A>C (p.Lys816Gln)
c.2368A>C (p.Lys790Gln)
n.2888A>C
5g.56882057A>GCA359786844MAP3K1c.2857A>G (p.Lys953Glu)
c.2479A>G (p.Lys827Glu)
c.2602A>G (p.Lys868Glu)
c.2578A>G (p.Lys860Glu)
c.2446A>G (p.Lys816Glu)
c.2368A>G (p.Lys790Glu)
n.2888A>G
5g.56882057A>TCA359786845MAP3K1c.2857A>T (p.Lys953Ter)
c.2479A>T (p.Lys827Ter)
c.2602A>T (p.Lys868Ter)
c.2578A>T (p.Lys860Ter)
c.2446A>T (p.Lys816Ter)
c.2368A>T (p.Lys790Ter)
n.2888A>T
5g.56882058A>CCA359786848MAP3K1c.2858A>C (p.Lys953Thr)
c.2480A>C (p.Lys827Thr)
c.2603A>C (p.Lys868Thr)
c.2579A>C (p.Lys860Thr)
c.2447A>C (p.Lys816Thr)
c.2369A>C (p.Lys790Thr)
n.2889A>C
5g.56882058A>GCA359786850MAP3K1c.2858A>G (p.Lys953Arg)
c.2480A>G (p.Lys827Arg)
c.2603A>G (p.Lys868Arg)
c.2579A>G (p.Lys860Arg)
c.2447A>G (p.Lys816Arg)
c.2369A>G (p.Lys790Arg)
n.2889A>G
5g.56882058A>TCA359786851MAP3K1c.2858A>T (p.Lys953Met)
c.2480A>T (p.Lys827Met)
c.2603A>T (p.Lys868Met)
c.2579A>T (p.Lys860Met)
c.2447A>T (p.Lys816Met)
c.2369A>T (p.Lys790Met)
n.2889A>T
5g.56882059G>ACA444399424MAP3K1c.2859G>A (p.Lys953=)
c.2481G>A (p.Lys827=)
c.2604G>A (p.Lys868=)
c.2580G>A (p.Lys860=)
c.2448G>A (p.Lys816=)
c.2370G>A (p.Lys790=)
n.2890G>A
 gnomAD v4
5g.56882059G>CCA359786852MAP3K1c.2859G>C (p.Lys953Asn)
c.2481G>C (p.Lys827Asn)
c.2604G>C (p.Lys868Asn)
c.2580G>C (p.Lys860Asn)
c.2448G>C (p.Lys816Asn)
c.2370G>C (p.Lys790Asn)
n.2890G>C
5g.56882059G>TCA359786854MAP3K1c.2859G>T (p.Lys953Asn)
c.2481G>T (p.Lys827Asn)
c.2604G>T (p.Lys868Asn)
c.2580G>T (p.Lys860Asn)
c.2448G>T (p.Lys816Asn)
c.2370G>T (p.Lys790Asn)
n.2890G>T
5g.56882060C>ACA359786856MAP3K1c.2860C>A (p.Pro954Thr)
c.2482C>A (p.Pro828Thr)
c.2605C>A (p.Pro869Thr)
c.2581C>A (p.Pro861Thr)
c.2449C>A (p.Pro817Thr)
c.2371C>A (p.Pro791Thr)
n.2891C>A
 dbSNP COSMIC
5g.56882060C>GCA359786858MAP3K1c.2860C>G (p.Pro954Ala)
c.2482C>G (p.Pro828Ala)
c.2605C>G (p.Pro869Ala)
c.2581C>G (p.Pro861Ala)
c.2449C>G (p.Pro817Ala)
c.2371C>G (p.Pro791Ala)
n.2891C>G
5g.56882060C>TCA359786860MAP3K1c.2860C>T (p.Pro954Ser)
c.2482C>T (p.Pro828Ser)
c.2605C>T (p.Pro869Ser)
c.2581C>T (p.Pro861Ser)
c.2449C>T (p.Pro817Ser)
c.2371C>T (p.Pro791Ser)
n.2891C>T
5g.56882061C>ACA359786866MAP3K1c.2861C>A (p.Pro954Gln)
c.2483C>A (p.Pro828Gln)
c.2606C>A (p.Pro869Gln)
c.2582C>A (p.Pro861Gln)
c.2450C>A (p.Pro817Gln)
c.2372C>A (p.Pro791Gln)
n.2892C>A
 dbSNP gnomAD v2 gnomAD v4
5g.56882061C=CA1548139431MAP3K1c.2861C= (p.Pro954=)
c.2483C= (p.Pro828=)
c.2606C= (p.Pro869=)
c.2582C= (p.Pro861=)
c.2450C= (p.Pro817=)
c.2372C= (p.Pro791=)
n.2892C=
5g.56882061C>GCA359786862MAP3K1c.2861C>G (p.Pro954Arg)
c.2483C>G (p.Pro828Arg)
c.2606C>G (p.Pro869Arg)
c.2582C>G (p.Pro861Arg)
c.2450C>G (p.Pro817Arg)
c.2372C>G (p.Pro791Arg)
n.2892C>G
 dbSNP
5g.56882061C>TCA359786864MAP3K1c.2861C>T (p.Pro954Leu)
c.2483C>T (p.Pro828Leu)
c.2606C>T (p.Pro869Leu)
c.2582C>T (p.Pro861Leu)
c.2450C>T (p.Pro817Leu)
c.2372C>T (p.Pro791Leu)
n.2892C>T
5g.56882061_56882062insCACA2578314343MAP3K1c.2861_2862insCA (p.Met955LysfsTer14)
c.2483_2484insCA (p.Met829LysfsTer14)
c.2606_2607insCA (p.Met870LysfsTer14)
c.2582_2583insCA (p.Met862LysfsTer14)
c.2450_2451insCA (p.Met818LysfsTer14)
c.2372_2373insCA (p.Met792LysfsTer14)
n.2892_2893insCA
5g.56882062A>CCA444399426MAP3K1c.2862A>C (p.Pro954=)
c.2484A>C (p.Pro828=)
c.2607A>C (p.Pro869=)
c.2583A>C (p.Pro861=)
c.2451A>C (p.Pro817=)
c.2373A>C (p.Pro791=)
n.2893A>C
5g.56882062A>GCA444399428MAP3K1c.2862A>G (p.Pro954=)
c.2484A>G (p.Pro828=)
c.2607A>G (p.Pro869=)
c.2583A>G (p.Pro861=)
c.2451A>G (p.Pro817=)
c.2373A>G (p.Pro791=)
n.2893A>G
5g.56882062A>TCA444399430MAP3K1c.2862A>T (p.Pro954=)
c.2484A>T (p.Pro828=)
c.2607A>T (p.Pro869=)
c.2583A>T (p.Pro861=)
c.2451A>T (p.Pro817=)
c.2373A>T (p.Pro791=)
n.2893A>T
5g.56882063A=CA1548139432MAP3K1c.2863A= (p.Met955=)
c.2485A= (p.Met829=)
c.2608A= (p.Met870=)
c.2584A= (p.Met862=)
c.2452A= (p.Met818=)
c.2374A= (p.Met792=)
n.2894A=
5g.56882063A>CCA359786867MAP3K1c.2863A>C (p.Met955Leu)
c.2485A>C (p.Met829Leu)
c.2608A>C (p.Met870Leu)
c.2584A>C (p.Met862Leu)
c.2452A>C (p.Met818Leu)
c.2374A>C (p.Met792Leu)
n.2894A>C
5g.56882063A>GCA3273077MAP3K1c.2863A>G (p.Met955Val)
c.2485A>G (p.Met829Val)
c.2608A>G (p.Met870Val)
c.2584A>G (p.Met862Val)
c.2452A>G (p.Met818Val)
c.2374A>G (p.Met792Val)
n.2894A>G
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882063A>TCA359786868MAP3K1c.2863A>T (p.Met955Leu)
c.2485A>T (p.Met829Leu)
c.2608A>T (p.Met870Leu)
c.2584A>T (p.Met862Leu)
c.2452A>T (p.Met818Leu)
c.2374A>T (p.Met792Leu)
n.2894A>T
5g.56882064T>ACA359786871MAP3K1c.2864T>A (p.Met955Lys)
c.2486T>A (p.Met829Lys)
c.2609T>A (p.Met870Lys)
c.2585T>A (p.Met862Lys)
c.2453T>A (p.Met818Lys)
c.2375T>A (p.Met792Lys)
n.2895T>A
5g.56882064T>CCA3273078MAP3K1c.2864T>C (p.Met955Thr)
c.2486T>C (p.Met829Thr)
c.2609T>C (p.Met870Thr)
c.2585T>C (p.Met862Thr)
c.2453T>C (p.Met818Thr)
c.2375T>C (p.Met792Thr)
n.2895T>C
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
5g.56882064T>GCA359786872MAP3K1c.2864T>G (p.Met955Arg)
c.2486T>G (p.Met829Arg)
c.2609T>G (p.Met870Arg)
c.2585T>G (p.Met862Arg)
c.2453T>G (p.Met818Arg)
c.2375T>G (p.Met792Arg)
n.2895T>G
5g.56882064T=CA1548139433MAP3K1c.2864T= (p.Met955=)
c.2486T= (p.Met829=)
c.2609T= (p.Met870=)
c.2585T= (p.Met862=)
c.2453T= (p.Met818=)
c.2375T= (p.Met792=)
n.2895T=
5g.56882065G>ACA359786876MAP3K1c.2865G>A (p.Met955Ile)
c.2487G>A (p.Met829Ile)
c.2610G>A (p.Met870Ile)
c.2586G>A (p.Met862Ile)
c.2454G>A (p.Met818Ile)
c.2376G>A (p.Met792Ile)
n.2896G>A
 gnomAD v4
5g.56882065G>CCA359786877MAP3K1c.2865G>C (p.Met955Ile)
c.2487G>C (p.Met829Ile)
c.2610G>C (p.Met870Ile)
c.2586G>C (p.Met862Ile)
c.2454G>C (p.Met818Ile)
c.2376G>C (p.Met792Ile)
n.2896G>C
5g.56882065G>TCA359786879MAP3K1c.2865G>T (p.Met955Ile)
c.2487G>T (p.Met829Ile)
c.2610G>T (p.Met870Ile)
c.2586G>T (p.Met862Ile)
c.2454G>T (p.Met818Ile)
c.2376G>T (p.Met792Ile)
n.2896G>T
5g.56882066G>ACA359786881MAP3K1c.2866G>A (p.Val956Ile)
c.2488G>A (p.Val830Ile)
c.2611G>A (p.Val871Ile)
c.2587G>A (p.Val863Ile)
c.2455G>A (p.Val819Ile)
c.2377G>A (p.Val793Ile)
n.2897G>A
5g.56882066G>CCA359786882MAP3K1c.2866G>C (p.Val956Leu)
c.2488G>C (p.Val830Leu)
c.2611G>C (p.Val871Leu)
c.2587G>C (p.Val863Leu)
c.2455G>C (p.Val819Leu)
c.2377G>C (p.Val793Leu)
n.2897G>C
5g.56882066G=CA1548139434MAP3K1c.2866G= (p.Val956=)
c.2488G= (p.Val830=)
c.2611G= (p.Val871=)
c.2587G= (p.Val863=)
c.2455G= (p.Val819=)
c.2377G= (p.Val793=)
n.2897G=
5g.56882066G>TCA119079723MAP3K1c.2866G>T (p.Val956Phe)
c.2488G>T (p.Val830Phe)
c.2611G>T (p.Val871Phe)
c.2587G>T (p.Val863Phe)
c.2455G>T (p.Val819Phe)
c.2377G>T (p.Val793Phe)
n.2897G>T
 dbSNP

Number of alleles fetched