Chr Mutation (hg38) CAid Gene Transcript Linkouts
16g.31091239A>CCA395729632VKORC1c.387T>G (p.Tyr129Ter)
c.448T>G (p.Ter150Gly)
c.469T>G (p.Ter157Gly)
c.277T>G (p.Ter93Gly)
c.481T>G (p.Ter161Gly)
c.349T>G
c.72T>G (p.Tyr24Ter)
c.484T>G (p.Ter162Gly)
c.283+2073T>G (n.283+2073T>G)
c.173+3318T>G (n.173+3318T>G)
c.260T>G
c.471T>G (p.Tyr157Ter)
n.1175T>G
16g.31091239A>GCA395729634VKORC1c.387T>C (p.Tyr129=)
c.448T>C (p.Ter150Arg)
c.469T>C (p.Ter157Arg)
c.277T>C (p.Ter93Arg)
c.481T>C (p.Ter161Arg)
c.349T>C
c.72T>C (p.Tyr24=)
c.484T>C (p.Ter162Arg)
c.283+2073T>C (n.283+2073T>C)
c.173+3318T>C (n.173+3318T>C)
c.260T>C
c.471T>C (p.Tyr157=)
n.1175T>C
 gnomAD v4
16g.31091239A>TCA395729636VKORC1c.387T>A (p.Tyr129Ter)
c.448T>A (p.Ter150Arg)
c.469T>A (p.Ter157Arg)
c.277T>A (p.Ter93Arg)
c.481T>A (p.Ter161Arg)
c.349T>A
c.72T>A (p.Tyr24Ter)
c.484T>A (p.Ter162Arg)
c.283+2073T>A (n.283+2073T>A)
c.173+3318T>A (n.173+3318T>A)
c.260T>A
c.471T>A (p.Tyr157Ter)
n.1175T>A
16g.31091240_31091241delCA2632821519VKORC1c.386_387del (p.Tyr129Ter)
c.447_448del (p.Ter150IleextTer14)
c.468_469del (p.Ter157IleextTer14)
c.276_277del (p.Ter93IleextTer14)
c.480_481del (p.Ter161IleextTer14)
c.348_349del
c.71_72del (p.Tyr24Ter)
c.483_484del (p.Ter162IleextTer14)
c.283+2072_283+2073del (n.283+2072_283+2073del)
c.173+3317_173+3318del (n.173+3317_173+3318del)
c.259_260del
c.470_471del (p.Tyr157Ter)
n.1174_1175del
 gnomAD v4
16g.31091240T>ACA395729641VKORC1c.386A>T (p.Tyr129Phe)
c.447A>T (p.Leu149=)
c.468A>T (p.Leu156=)
c.276A>T (p.Leu92=)
c.480A>T (p.Leu160=)
c.348A>T
c.71A>T (p.Tyr24Phe)
c.483A>T (p.Leu161=)
c.283+2072A>T (n.283+2072A>T)
c.173+3317A>T (n.173+3317A>T)
c.259A>T
c.470A>T (p.Tyr157Phe)
n.1174A>T
16g.31091240T>CCA395729638VKORC1c.386A>G (p.Tyr129Cys)
c.447A>G (p.Leu149=)
c.468A>G (p.Leu156=)
c.276A>G (p.Leu92=)
c.480A>G (p.Leu160=)
c.348A>G
c.71A>G (p.Tyr24Cys)
c.483A>G (p.Leu161=)
c.283+2072A>G (n.283+2072A>G)
c.173+3317A>G (n.173+3317A>G)
c.259A>G
c.470A>G (p.Tyr157Cys)
n.1174A>G
 dbSNP gnomAD v4
16g.31091240T>GCA395729640VKORC1c.386A>C (p.Tyr129Ser)
c.447A>C (p.Leu149=)
c.468A>C (p.Leu156=)
c.276A>C (p.Leu92=)
c.480A>C (p.Leu160=)
c.348A>C
c.71A>C (p.Tyr24Ser)
c.483A>C (p.Leu161=)
c.283+2072A>C (n.283+2072A>C)
c.173+3317A>C (n.173+3317A>C)
c.259A>C
c.470A>C (p.Tyr157Ser)
n.1174A>C
 gnomAD v4
16g.31091240T=CA2216889100VKORC1c.386A= (p.Tyr129=)
c.447A= (p.Leu149=)
c.468A= (p.Leu156=)
c.276A= (p.Leu92=)
c.480A= (p.Leu160=)
c.348A=
c.71A= (p.Tyr24=)
c.483A= (p.Leu161=)
c.283+2072A= (n.283+2072A=)
c.173+3317A= (n.173+3317A=)
c.259A=
c.470A= (p.Tyr157=)
n.1174A=
16g.31091241A>CCA395729642VKORC1c.385T>G (p.Tyr129Asp)
c.446T>G (p.Leu149Arg)
c.467T>G (p.Leu156Arg)
c.275T>G (p.Leu92Arg)
c.479T>G (p.Leu160Arg)
c.347T>G
c.70T>G (p.Tyr24Asp)
c.482T>G (p.Leu161Arg)
c.283+2071T>G (n.283+2071T>G)
c.173+3316T>G (n.173+3316T>G)
c.258T>G
c.469T>G (p.Tyr157Asp)
n.1173T>G
16g.31091241A>GCA395729643VKORC1c.385T>C (p.Tyr129His)
c.446T>C (p.Leu149Pro)
c.467T>C (p.Leu156Pro)
c.275T>C (p.Leu92Pro)
c.479T>C (p.Leu160Pro)
c.347T>C
c.70T>C (p.Tyr24His)
c.482T>C (p.Leu161Pro)
c.283+2071T>C (n.283+2071T>C)
c.173+3316T>C (n.173+3316T>C)
c.258T>C
c.469T>C (p.Tyr157His)
n.1173T>C
16g.31091241A>TCA395729645VKORC1c.385T>A (p.Tyr129Asn)
c.446T>A (p.Leu149Gln)
c.467T>A (p.Leu156Gln)
c.275T>A (p.Leu92Gln)
c.479T>A (p.Leu160Gln)
c.347T>A
c.70T>A (p.Tyr24Asn)
c.482T>A (p.Leu161Gln)
c.283+2071T>A (n.283+2071T>A)
c.173+3316T>A (n.173+3316T>A)
c.258T>A
c.469T>A (p.Tyr157Asn)
n.1173T>A
16g.31091242G>ACA494925951VKORC1c.384C>T (p.Leu128=)
c.445C>T (p.Leu149=)
c.466C>T (p.Leu156=)
c.274C>T (p.Leu92=)
c.478C>T (p.Leu160=)
c.346C>T
c.69C>T (p.Leu23=)
c.481C>T (p.Leu161=)
c.283+2070C>T (n.283+2070C>T)
c.173+3315C>T (n.173+3315C>T)
c.257C>T
c.468C>T (p.Leu156=)
n.1172C>T
 gnomAD v4
16g.31091242G>CCA395729647VKORC1c.384C>G (p.Leu128=)
c.445C>G (p.Leu149Val)
c.466C>G (p.Leu156Val)
c.274C>G (p.Leu92Val)
c.478C>G (p.Leu160Val)
c.346C>G
c.69C>G (p.Leu23=)
c.481C>G (p.Leu161Val)
c.283+2070C>G (n.283+2070C>G)
c.173+3315C>G (n.173+3315C>G)
c.257C>G
c.468C>G (p.Leu156=)
n.1172C>G
16g.31091242G>TCA395729649VKORC1c.384C>A (p.Leu128=)
c.445C>A (p.Leu149Ile)
c.466C>A (p.Leu156Ile)
c.274C>A (p.Leu92Ile)
c.478C>A (p.Leu160Ile)
c.346C>A
c.69C>A (p.Leu23=)
c.481C>A (p.Leu161Ile)
c.283+2070C>A (n.283+2070C>A)
c.173+3315C>A (n.173+3315C>A)
c.257C>A
c.468C>A (p.Leu156=)
n.1172C>A
16g.31091243A=CA2216889106VKORC1c.383T= (p.Leu128=)
c.444T= (p.Ala148=)
c.465T= (p.Ala155=)
c.273T= (p.Ala91=)
c.477T= (p.Ala159=)
c.345T=
c.68T= (p.Leu23=)
c.480T= (p.Ala160=)
c.283+2069T= (n.283+2069T=)
c.173+3314T= (n.173+3314T=)
c.256T=
c.467T= (p.Leu156=)
n.1171T=
16g.31091243A>CCA115415VKORC1c.383T>G (p.Leu128Arg)
c.444T>G (p.Ala148=)
c.465T>G (p.Ala155=)
c.273T>G (p.Ala91=)
c.477T>G (p.Ala159=)
c.345T>G
c.68T>G (p.Leu23Arg)
c.480T>G (p.Ala160=)
c.283+2069T>G (n.283+2069T>G)
c.173+3314T>G (n.173+3314T>G)
c.256T>G
c.467T>G (p.Leu156Arg)
n.1171T>G
 ClinVar dbSNP gnomAD v3 gnomAD v4
16g.31091243A>GCA395729653VKORC1c.383T>C (p.Leu128Pro)
c.444T>C (p.Ala148=)
c.465T>C (p.Ala155=)
c.273T>C (p.Ala91=)
c.477T>C (p.Ala159=)
c.345T>C
c.68T>C (p.Leu23Pro)
c.480T>C (p.Ala160=)
c.283+2069T>C (n.283+2069T>C)
c.173+3314T>C (n.173+3314T>C)
c.256T>C
c.467T>C (p.Leu156Pro)
n.1171T>C
16g.31091243A>TCA395729651VKORC1c.383T>A (p.Leu128His)
c.444T>A (p.Ala148=)
c.465T>A (p.Ala155=)
c.273T>A (p.Ala91=)
c.477T>A (p.Ala159=)
c.345T>A
c.68T>A (p.Leu23His)
c.480T>A (p.Ala160=)
c.283+2069T>A (n.283+2069T>A)
c.173+3314T>A (n.173+3314T>A)
c.256T>A
c.467T>A (p.Leu156His)
n.1171T>A
16g.31091244G>ACA395729655VKORC1c.382C>T (p.Leu128Phe)
c.443C>T (p.Ala148Val)
c.464C>T (p.Ala155Val)
c.272C>T (p.Ala91Val)
c.476C>T (p.Ala159Val)
c.344C>T
c.67C>T (p.Leu23Phe)
c.479C>T (p.Ala160Val)
c.283+2068C>T (n.283+2068C>T)
c.173+3313C>T (n.173+3313C>T)
c.255C>T
c.466C>T (p.Leu156Phe)
n.1170C>T
 gnomAD v4
16g.31091244G>CCA395729657VKORC1c.382C>G (p.Leu128Val)
c.443C>G (p.Ala148Gly)
c.464C>G (p.Ala155Gly)
c.272C>G (p.Ala91Gly)
c.476C>G (p.Ala159Gly)
c.344C>G
c.67C>G (p.Leu23Val)
c.479C>G (p.Ala160Gly)
c.283+2068C>G (n.283+2068C>G)
c.173+3313C>G (n.173+3313C>G)
c.255C>G
c.466C>G (p.Leu156Val)
n.1170C>G
16g.31091244G>TCA395729658VKORC1c.382C>A (p.Leu128Ile)
c.443C>A (p.Ala148Asp)
c.464C>A (p.Ala155Asp)
c.272C>A (p.Ala91Asp)
c.476C>A (p.Ala159Asp)
c.344C>A
c.67C>A (p.Leu23Ile)
c.479C>A (p.Ala160Asp)
c.283+2068C>A (n.283+2068C>A)
c.173+3313C>A (n.173+3313C>A)
c.255C>A
c.466C>A (p.Leu156Ile)
n.1170C>A
16g.31091245C>ACA395729660VKORC1c.381G>T (p.Val127=)
c.442G>T (p.Ala148Ser)
c.463G>T (p.Ala155Ser)
c.271G>T (p.Ala91Ser)
c.475G>T (p.Ala159Ser)
c.343G>T
c.66G>T (p.Val22=)
c.478G>T (p.Ala160Ser)
c.283+2067G>T (n.283+2067G>T)
c.173+3312G>T (n.173+3312G>T)
c.254G>T
c.465G>T (p.Val155=)
n.1169G>T
16g.31091245C>GCA395729661VKORC1c.381G>C (p.Val127=)
c.442G>C (p.Ala148Pro)
c.463G>C (p.Ala155Pro)
c.271G>C (p.Ala91Pro)
c.475G>C (p.Ala159Pro)
c.343G>C
c.66G>C (p.Val22=)
c.478G>C (p.Ala160Pro)
c.283+2067G>C (n.283+2067G>C)
c.173+3312G>C (n.173+3312G>C)
c.254G>C
c.465G>C (p.Val155=)
n.1169G>C
16g.31091245C>TCA395729662VKORC1c.381G>A (p.Val127=)
c.442G>A (p.Ala148Thr)
c.463G>A (p.Ala155Thr)
c.271G>A (p.Ala91Thr)
c.475G>A (p.Ala159Thr)
c.343G>A
c.66G>A (p.Val22=)
c.478G>A (p.Ala160Thr)
c.283+2067G>A (n.283+2067G>A)
c.173+3312G>A (n.173+3312G>A)
c.254G>A
c.465G>A (p.Val155=)
n.1169G>A
16g.31091246A>CCA395729663VKORC1c.380T>G (p.Val127Gly)
c.441T>G (p.Arg147=)
c.462T>G (p.Arg154=)
c.270T>G (p.Arg90=)
c.474T>G (p.Arg158=)
c.342T>G
c.65T>G (p.Val22Gly)
c.477T>G (p.Arg159=)
c.283+2066T>G (n.283+2066T>G)
c.173+3311T>G (n.173+3311T>G)
c.253T>G
c.464T>G (p.Val155Gly)
n.1168T>G
16g.31091246A>GCA395729665VKORC1c.380T>C (p.Val127Ala)
c.441T>C (p.Arg147=)
c.462T>C (p.Arg154=)
c.270T>C (p.Arg90=)
c.474T>C (p.Arg158=)
c.342T>C
c.65T>C (p.Val22Ala)
c.477T>C (p.Arg159=)
c.283+2066T>C (n.283+2066T>C)
c.173+3311T>C (n.173+3311T>C)
c.253T>C
c.464T>C (p.Val155Ala)
n.1168T>C
16g.31091246A>TCA395729666VKORC1c.380T>A (p.Val127Glu)
c.441T>A (p.Arg147=)
c.462T>A (p.Arg154=)
c.270T>A (p.Arg90=)
c.474T>A (p.Arg158=)
c.342T>A
c.65T>A (p.Val22Glu)
c.477T>A (p.Arg159=)
c.283+2066T>A (n.283+2066T>A)
c.173+3311T>A (n.173+3311T>A)
c.253T>A
c.464T>A (p.Val155Glu)
n.1168T>A
16g.31091247C>ACA395729667VKORC1c.379G>T (p.Val127Leu)
c.440G>T (p.Arg147Leu)
c.461G>T (p.Arg154Leu)
c.269G>T (p.Arg90Leu)
c.473G>T (p.Arg158Leu)
c.341G>T
c.64G>T (p.Val22Leu)
c.476G>T (p.Arg159Leu)
c.283+2065G>T (n.283+2065G>T)
c.173+3310G>T (n.173+3310G>T)
c.252G>T
c.463G>T (p.Val155Leu)
n.1167G>T
 gnomAD v4
16g.31091247C=CA2216889116VKORC1c.379G= (p.Val127=)
c.440G= (p.Arg147=)
c.461G= (p.Arg154=)
c.269G= (p.Arg90=)
c.473G= (p.Arg158=)
c.341G=
c.64G= (p.Val22=)
c.476G= (p.Arg159=)
c.283+2065G= (n.283+2065G=)
c.173+3310G= (n.173+3310G=)
c.252G=
c.463G= (p.Val155=)
n.1167G=
16g.31091247C>GCA395729668VKORC1c.379G>C (p.Val127Leu)
c.440G>C (p.Arg147Pro)
c.461G>C (p.Arg154Pro)
c.269G>C (p.Arg90Pro)
c.473G>C (p.Arg158Pro)
c.341G>C
c.64G>C (p.Val22Leu)
c.476G>C (p.Arg159Pro)
c.283+2065G>C (n.283+2065G>C)
c.173+3310G>C (n.173+3310G>C)
c.252G>C
c.463G>C (p.Val155Leu)
n.1167G>C
 dbSNP gnomAD v3 gnomAD v4
16g.31091247C>TCA8021124VKORC1c.379G>A (p.Val127Met)
c.440G>A (p.Arg147His)
c.461G>A (p.Arg154His)
c.269G>A (p.Arg90His)
c.473G>A (p.Arg158His)
c.341G>A
c.64G>A (p.Val22Met)
c.476G>A (p.Arg159His)
c.283+2065G>A (n.283+2065G>A)
c.173+3310G>A (n.173+3310G>A)
c.252G>A
c.463G>A (p.Val155Met)
n.1167G>A
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
16g.31091248G>ACA8021125VKORC1c.378C>T (p.Phe126=)
c.439C>T (p.Arg147Cys)
c.460C>T (p.Arg154Cys)
c.268C>T (p.Arg90Cys)
c.472C>T (p.Arg158Cys)
c.340C>T
c.63C>T (p.Phe21=)
c.475C>T (p.Arg159Cys)
c.283+2064C>T (n.283+2064C>T)
c.173+3309C>T (n.173+3309C>T)
c.251C>T
c.462C>T (p.Phe154=)
n.1166C>T
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
16g.31091248G>CCA395729672VKORC1c.378C>G (p.Phe126Leu)
c.439C>G (p.Arg147Gly)
c.460C>G (p.Arg154Gly)
c.268C>G (p.Arg90Gly)
c.472C>G (p.Arg158Gly)
c.340C>G
c.63C>G (p.Phe21Leu)
c.475C>G (p.Arg159Gly)
c.283+2064C>G (n.283+2064C>G)
c.173+3309C>G (n.173+3309C>G)
c.251C>G
c.462C>G (p.Phe154Leu)
n.1166C>G
16g.31091248G=CA2216889119VKORC1c.378C= (p.Phe126=)
c.439C= (p.Arg147=)
c.460C= (p.Arg154=)
c.268C= (p.Arg90=)
c.472C= (p.Arg158=)
c.340C=
c.63C= (p.Phe21=)
c.475C= (p.Arg159=)
c.283+2064C= (n.283+2064C=)
c.173+3309C= (n.173+3309C=)
c.251C=
c.462C= (p.Phe154=)
n.1166C=
16g.31091248G>TCA395729670VKORC1c.378C>A (p.Phe126Leu)
c.439C>A (p.Arg147Ser)
c.460C>A (p.Arg154Ser)
c.268C>A (p.Arg90Ser)
c.472C>A (p.Arg158Ser)
c.340C>A
c.63C>A (p.Phe21Leu)
c.475C>A (p.Arg159Ser)
c.283+2064C>A (n.283+2064C>A)
c.173+3309C>A (n.173+3309C>A)
c.251C>A
c.462C>A (p.Phe154Leu)
n.1166C>A
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
16g.31091251_31091253delCA2632821520VKORC1c.376_378del (p.Phe126del)
c.437_439del (p.Leu146del)
c.458_460del (p.Leu153del)
c.266_268del (p.Leu89del)
c.470_472del (p.Leu157del)
c.338_340del
c.61_63del (p.Phe21del)
c.473_475del (p.Leu158del)
c.283+2062_283+2064del (n.283+2062_283+2064del)
c.173+3307_173+3309del (n.173+3307_173+3309del)
c.249_251del
c.460_462del (p.Phe154del)
n.1164_1166del
 gnomAD v4
16g.31091249A=CA2216889126VKORC1c.377T= (p.Phe126=)
c.438T= (p.Leu146=)
c.459T= (p.Leu153=)
c.267T= (p.Leu89=)
c.471T= (p.Leu157=)
c.339T=
c.62T= (p.Phe21=)
c.474T= (p.Leu158=)
c.283+2063T= (n.283+2063T=)
c.173+3308T= (n.173+3308T=)
c.250T=
c.461T= (p.Phe154=)
n.1165T=
16g.31091249A>CCA395729675VKORC1c.377T>G (p.Phe126Cys)
c.438T>G (p.Leu146=)
c.459T>G (p.Leu153=)
c.267T>G (p.Leu89=)
c.471T>G (p.Leu157=)
c.339T>G
c.62T>G (p.Phe21Cys)
c.474T>G (p.Leu158=)
c.283+2063T>G (n.283+2063T>G)
c.173+3308T>G (n.173+3308T>G)
c.250T>G
c.461T>G (p.Phe154Cys)
n.1165T>G
16g.31091249A>GCA280619941VKORC1c.377T>C (p.Phe126Ser)
c.438T>C (p.Leu146=)
c.459T>C (p.Leu153=)
c.267T>C (p.Leu89=)
c.471T>C (p.Leu157=)
c.339T>C
c.62T>C (p.Phe21Ser)
c.474T>C (p.Leu158=)
c.283+2063T>C (n.283+2063T>C)
c.173+3308T>C (n.173+3308T>C)
c.250T>C
c.461T>C (p.Phe154Ser)
n.1165T>C
 dbSNP gnomAD v3 gnomAD v4
16g.31091249A>TCA395729677VKORC1c.377T>A (p.Phe126Tyr)
c.438T>A (p.Leu146=)
c.459T>A (p.Leu153=)
c.267T>A (p.Leu89=)
c.471T>A (p.Leu157=)
c.339T>A
c.62T>A (p.Phe21Tyr)
c.474T>A (p.Leu158=)
c.283+2063T>A (n.283+2063T>A)
c.173+3308T>A (n.173+3308T>A)
c.250T>A
c.461T>A (p.Phe154Tyr)
n.1165T>A
16g.31091250A>CCA395729679VKORC1c.376T>G (p.Phe126Val)
c.437T>G (p.Leu146Arg)
c.458T>G (p.Leu153Arg)
c.266T>G (p.Leu89Arg)
c.470T>G (p.Leu157Arg)
c.338T>G
c.61T>G (p.Phe21Val)
c.473T>G (p.Leu158Arg)
c.283+2062T>G (n.283+2062T>G)
c.173+3307T>G (n.173+3307T>G)
c.249T>G
c.460T>G (p.Phe154Val)
n.1164T>G
16g.31091250A>GCA395729680VKORC1c.376T>C (p.Phe126Leu)
c.437T>C (p.Leu146Pro)
c.458T>C (p.Leu153Pro)
c.266T>C (p.Leu89Pro)
c.470T>C (p.Leu157Pro)
c.338T>C
c.61T>C (p.Phe21Leu)
c.473T>C (p.Leu158Pro)
c.283+2062T>C (n.283+2062T>C)
c.173+3307T>C (n.173+3307T>C)
c.249T>C
c.460T>C (p.Phe154Leu)
n.1164T>C
16g.31091250A>TCA395729682VKORC1c.376T>A (p.Phe126Ile)
c.437T>A (p.Leu146His)
c.458T>A (p.Leu153His)
c.266T>A (p.Leu89His)
c.470T>A (p.Leu157His)
c.338T>A
c.61T>A (p.Phe21Ile)
c.473T>A (p.Leu158His)
c.283+2062T>A (n.283+2062T>A)
c.173+3307T>A (n.173+3307T>A)
c.249T>A
c.460T>A (p.Phe154Ile)
n.1164T>A
16g.31091251G>ACA395729683VKORC1c.375C>T (p.Phe125=)
c.436C>T (p.Leu146Phe)
c.457C>T (p.Leu153Phe)
c.265C>T (p.Leu89Phe)
c.469C>T (p.Leu157Phe)
c.337C>T
c.60C>T (p.Phe20=)
c.472C>T (p.Leu158Phe)
c.283+2061C>T (n.283+2061C>T)
c.173+3306C>T (n.173+3306C>T)
c.248C>T
c.459C>T (p.Phe153=)
n.1163C>T
16g.31091251G>CCA8021126VKORC1c.375C>G (p.Phe125Leu)
c.436C>G (p.Leu146Val)
c.457C>G (p.Leu153Val)
c.265C>G (p.Leu89Val)
c.469C>G (p.Leu157Val)
c.337C>G
c.60C>G (p.Phe20Leu)
c.472C>G (p.Leu158Val)
c.283+2061C>G (n.283+2061C>G)
c.173+3306C>G (n.173+3306C>G)
c.248C>G
c.459C>G (p.Phe153Leu)
n.1163C>G
 dbSNP ExAC gnomAD v2 gnomAD v4
16g.31091251G=CA2216889131VKORC1c.375C= (p.Phe125=)
c.436C= (p.Leu146=)
c.457C= (p.Leu153=)
c.265C= (p.Leu89=)
c.469C= (p.Leu157=)
c.337C=
c.60C= (p.Phe20=)
c.472C= (p.Leu158=)
c.283+2061C= (n.283+2061C=)
c.173+3306C= (n.173+3306C=)
c.248C=
c.459C= (p.Phe153=)
n.1163C=
16g.31091251G>TCA395729685VKORC1c.375C>A (p.Phe125Leu)
c.436C>A (p.Leu146Ile)
c.457C>A (p.Leu153Ile)
c.265C>A (p.Leu89Ile)
c.469C>A (p.Leu157Ile)
c.337C>A
c.60C>A (p.Phe20Leu)
c.472C>A (p.Leu158Ile)
c.283+2061C>A (n.283+2061C>A)
c.173+3306C>A (n.173+3306C>A)
c.248C>A
c.459C>A (p.Phe153Leu)
n.1163C>A
16g.31091252A>CCA395729690VKORC1c.374T>G (p.Phe125Cys)
c.435T>G (p.Val145=)
c.456T>G (p.Val152=)
c.264T>G (p.Val88=)
c.468T>G (p.Val156=)
c.336T>G
c.59T>G (p.Phe20Cys)
c.471T>G (p.Val157=)
c.283+2060T>G (n.283+2060T>G)
c.173+3305T>G (n.173+3305T>G)
c.247T>G
c.458T>G (p.Phe153Cys)
n.1162T>G
16g.31091252A>GCA395729692VKORC1c.374T>C (p.Phe125Ser)
c.435T>C (p.Val145=)
c.456T>C (p.Val152=)
c.264T>C (p.Val88=)
c.468T>C (p.Val156=)
c.336T>C
c.59T>C (p.Phe20Ser)
c.471T>C (p.Val157=)
c.283+2060T>C (n.283+2060T>C)
c.173+3305T>C (n.173+3305T>C)
c.247T>C
c.458T>C (p.Phe153Ser)
n.1162T>C
16g.31091252A>TCA395729694VKORC1c.374T>A (p.Phe125Tyr)
c.435T>A (p.Val145=)
c.456T>A (p.Val152=)
c.264T>A (p.Val88=)
c.468T>A (p.Val156=)
c.336T>A
c.59T>A (p.Phe20Tyr)
c.471T>A (p.Val157=)
c.283+2060T>A (n.283+2060T>A)
c.173+3305T>A (n.173+3305T>A)
c.247T>A
c.458T>A (p.Phe153Tyr)
n.1162T>A
16g.31091253A=CA2216889136VKORC1c.373T= (p.Phe125=)
c.434T= (p.Val145=)
c.455T= (p.Val152=)
c.263T= (p.Val88=)
c.467T= (p.Val156=)
c.335T=
c.58T= (p.Phe20=)
c.470T= (p.Val157=)
c.283+2059T= (n.283+2059T=)
c.173+3304T= (n.173+3304T=)
c.246T=
c.457T= (p.Phe153=)
n.1161T=
16g.31091253A>CCA395729700VKORC1c.373T>G (p.Phe125Val)
c.434T>G (p.Val145Gly)
c.455T>G (p.Val152Gly)
c.263T>G (p.Val88Gly)
c.467T>G (p.Val156Gly)
c.335T>G
c.58T>G (p.Phe20Val)
c.470T>G (p.Val157Gly)
c.283+2059T>G (n.283+2059T>G)
c.173+3304T>G (n.173+3304T>G)
c.246T>G
c.457T>G (p.Phe153Val)
n.1161T>G
16g.31091253A>GCA395729696VKORC1c.373T>C (p.Phe125Leu)
c.434T>C (p.Val145Ala)
c.455T>C (p.Val152Ala)
c.263T>C (p.Val88Ala)
c.467T>C (p.Val156Ala)
c.335T>C
c.58T>C (p.Phe20Leu)
c.470T>C (p.Val157Ala)
c.283+2059T>C (n.283+2059T>C)
c.173+3304T>C (n.173+3304T>C)
c.246T>C
c.457T>C (p.Phe153Leu)
n.1161T>C
16g.31091253A>TCA395729698VKORC1c.373T>A (p.Phe125Ile)
c.434T>A (p.Val145Asp)
c.455T>A (p.Val152Asp)
c.263T>A (p.Val88Asp)
c.467T>A (p.Val156Asp)
c.335T>A
c.58T>A (p.Phe20Ile)
c.470T>A (p.Val157Asp)
c.283+2059T>A (n.283+2059T>A)
c.173+3304T>A (n.173+3304T>A)
c.246T>A
c.457T>A (p.Phe153Ile)
n.1161T>A
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
16g.31091254C>ACA395729701VKORC1c.372G>T (p.Leu124=)
c.433G>T (p.Val145Phe)
c.454G>T (p.Val152Phe)
c.262G>T (p.Val88Phe)
c.466G>T (p.Val156Phe)
c.334G>T
c.57G>T (p.Leu19=)
c.469G>T (p.Val157Phe)
c.283+2058G>T (n.283+2058G>T)
c.173+3303G>T (n.173+3303G>T)
c.245G>T
c.456G>T (p.Leu152=)
n.1160G>T
16g.31091254C>GCA395729702VKORC1c.372G>C (p.Leu124=)
c.433G>C (p.Val145Leu)
c.454G>C (p.Val152Leu)
c.262G>C (p.Val88Leu)
c.466G>C (p.Val156Leu)
c.334G>C
c.57G>C (p.Leu19=)
c.469G>C (p.Val157Leu)
c.283+2058G>C (n.283+2058G>C)
c.173+3303G>C (n.173+3303G>C)
c.245G>C
c.456G>C (p.Leu152=)
n.1160G>C
16g.31091254C>TCA395729703VKORC1c.372G>A (p.Leu124=)
c.433G>A (p.Val145Ile)
c.454G>A (p.Val152Ile)
c.262G>A (p.Val88Ile)
c.466G>A (p.Val156Ile)
c.334G>A
c.57G>A (p.Leu19=)
c.469G>A (p.Val157Ile)
c.283+2058G>A (n.283+2058G>A)
c.173+3303G>A (n.173+3303G>A)
c.245G>A
c.456G>A (p.Leu152=)
n.1160G>A
16g.31091255A>CCA395729705VKORC1c.371T>G (p.Leu124Arg)
c.432T>G (p.Pro144=)
c.453T>G (p.Pro151=)
c.261T>G (p.Pro87=)
c.465T>G (p.Pro155=)
c.333T>G
c.56T>G (p.Leu19Arg)
c.468T>G (p.Pro156=)
c.283+2057T>G (n.283+2057T>G)
c.173+3302T>G (n.173+3302T>G)
c.244T>G
c.455T>G (p.Leu152Arg)
n.1159T>G
16g.31091255A>GCA395729707VKORC1c.371T>C (p.Leu124Pro)
c.432T>C (p.Pro144=)
c.453T>C (p.Pro151=)
c.261T>C (p.Pro87=)
c.465T>C (p.Pro155=)
c.333T>C
c.56T>C (p.Leu19Pro)
c.468T>C (p.Pro156=)
c.283+2057T>C (n.283+2057T>C)
c.173+3302T>C (n.173+3302T>C)
c.244T>C
c.455T>C (p.Leu152Pro)
n.1159T>C
16g.31091255A>TCA395729708VKORC1c.371T>A (p.Leu124Gln)
c.432T>A (p.Pro144=)
c.453T>A (p.Pro151=)
c.261T>A (p.Pro87=)
c.465T>A (p.Pro155=)
c.333T>A
c.56T>A (p.Leu19Gln)
c.468T>A (p.Pro156=)
c.283+2057T>A (n.283+2057T>A)
c.173+3302T>A (n.173+3302T>A)
c.244T>A
c.455T>A (p.Leu152Gln)
n.1159T>A
16g.31091256G>ACA395729709VKORC1c.370C>T (p.Leu124=)
c.431C>T (p.Pro144Leu)
c.452C>T (p.Pro151Leu)
c.260C>T (p.Pro87Leu)
c.464C>T (p.Pro155Leu)
c.332C>T
c.55C>T (p.Leu19=)
c.467C>T (p.Pro156Leu)
c.283+2056C>T (n.283+2056C>T)
c.173+3301C>T (n.173+3301C>T)
c.243C>T
c.454C>T (p.Leu152=)
n.1158C>T
16g.31091256G>CCA395729711VKORC1c.370C>G (p.Leu124Val)
c.431C>G (p.Pro144Arg)
c.452C>G (p.Pro151Arg)
c.260C>G (p.Pro87Arg)
c.464C>G (p.Pro155Arg)
c.332C>G
c.55C>G (p.Leu19Val)
c.467C>G (p.Pro156Arg)
c.283+2056C>G (n.283+2056C>G)
c.173+3301C>G (n.173+3301C>G)
c.243C>G
c.454C>G (p.Leu152Val)
n.1158C>G
 dbSNP gnomAD v2 gnomAD v4
16g.31091256G=CA2216889139VKORC1c.370C= (p.Leu124=)
c.431C= (p.Pro144=)
c.452C= (p.Pro151=)
c.260C= (p.Pro87=)
c.464C= (p.Pro155=)
c.332C=
c.55C= (p.Leu19=)
c.467C= (p.Pro156=)
c.283+2056C= (n.283+2056C=)
c.173+3301C= (n.173+3301C=)
c.243C=
c.454C= (p.Leu152=)
n.1158C=
16g.31091256G>TCA395729712VKORC1c.370C>A (p.Leu124Met)
c.431C>A (p.Pro144His)
c.452C>A (p.Pro151His)
c.260C>A (p.Pro87His)
c.464C>A (p.Pro155His)
c.332C>A
c.55C>A (p.Leu19Met)
c.467C>A (p.Pro156His)
c.283+2056C>A (n.283+2056C>A)
c.173+3301C>A (n.173+3301C>A)
c.243C>A
c.454C>A (p.Leu152Met)
n.1158C>A
16g.31091257G>ACA395729715VKORC1c.369C>T (p.Ile123=)
c.430C>T (p.Pro144Ser)
c.451C>T (p.Pro151Ser)
c.259C>T (p.Pro87Ser)
c.463C>T (p.Pro155Ser)
c.331C>T
c.54C>T (p.Ile18=)
c.466C>T (p.Pro156Ser)
c.283+2055C>T (n.283+2055C>T)
c.173+3300C>T (n.173+3300C>T)
c.242C>T
c.453C>T (p.Ile151=)
n.1157C>T
16g.31091257G>CCA395729716VKORC1c.369C>G (p.Ile123Met)
c.430C>G (p.Pro144Ala)
c.451C>G (p.Pro151Ala)
c.259C>G (p.Pro87Ala)
c.463C>G (p.Pro155Ala)
c.331C>G
c.54C>G (p.Ile18Met)
c.466C>G (p.Pro156Ala)
c.283+2055C>G (n.283+2055C>G)
c.173+3300C>G (n.173+3300C>G)
c.242C>G
c.453C>G (p.Ile151Met)
n.1157C>G
16g.31091257G=CA2216889145VKORC1c.369C= (p.Ile123=)
c.430C= (p.Pro144=)
c.451C= (p.Pro151=)
c.259C= (p.Pro87=)
c.463C= (p.Pro155=)
c.331C=
c.54C= (p.Ile18=)
c.466C= (p.Pro156=)
c.283+2055C= (n.283+2055C=)
c.173+3300C= (n.173+3300C=)
c.242C=
c.453C= (p.Ile151=)
n.1157C=
16g.31091257G>TCA395729717VKORC1c.369C>A (p.Ile123=)
c.430C>A (p.Pro144Thr)
c.451C>A (p.Pro151Thr)
c.259C>A (p.Pro87Thr)
c.463C>A (p.Pro155Thr)
c.331C>A
c.54C>A (p.Ile18=)
c.466C>A (p.Pro156Thr)
c.283+2055C>A (n.283+2055C>A)
c.173+3300C>A (n.173+3300C>A)
c.242C>A
c.453C>A (p.Ile151=)
n.1157C>A
 dbSNP
16g.31091258A>CCA395729719VKORC1c.368T>G (p.Ile123Ser)
c.429T>G (p.Asp143Glu)
c.450T>G (p.Asp150Glu)
c.258T>G (p.Asp86Glu)
c.462T>G (p.Asp154Glu)
c.330T>G
c.53T>G (p.Ile18Ser)
c.465T>G (p.Asp155Glu)
c.283+2054T>G (n.283+2054T>G)
c.173+3299T>G (n.173+3299T>G)
c.241T>G
c.452T>G (p.Ile151Ser)
n.1156T>G
16g.31091258A>GCA395729720VKORC1c.368T>C (p.Ile123Thr)
c.429T>C (p.Asp143=)
c.450T>C (p.Asp150=)
c.258T>C (p.Asp86=)
c.462T>C (p.Asp154=)
c.330T>C
c.53T>C (p.Ile18Thr)
c.465T>C (p.Asp155=)
c.283+2054T>C (n.283+2054T>C)
c.173+3299T>C (n.173+3299T>C)
c.241T>C
c.452T>C (p.Ile151Thr)
n.1156T>C
16g.31091258A>TCA395729718VKORC1c.368T>A (p.Ile123Asn)
c.429T>A (p.Asp143Glu)
c.450T>A (p.Asp150Glu)
c.258T>A (p.Asp86Glu)
c.462T>A (p.Asp154Glu)
c.330T>A
c.53T>A (p.Ile18Asn)
c.465T>A (p.Asp155Glu)
c.283+2054T>A (n.283+2054T>A)
c.173+3299T>A (n.173+3299T>A)
c.241T>A
c.452T>A (p.Ile151Asn)
n.1156T>A
16g.31091259T>ACA395729721VKORC1c.367A>T (p.Ile123Phe)
c.428A>T (p.Asp143Val)
c.449A>T (p.Asp150Val)
c.257A>T (p.Asp86Val)
c.461A>T (p.Asp154Val)
c.329A>T
c.52A>T (p.Ile18Phe)
c.464A>T (p.Asp155Val)
c.283+2053A>T (n.283+2053A>T)
c.173+3298A>T (n.173+3298A>T)
c.240A>T
c.451A>T (p.Ile151Phe)
n.1155A>T
16g.31091259T>CCA395729722VKORC1c.367A>G (p.Ile123Val)
c.428A>G (p.Asp143Gly)
c.449A>G (p.Asp150Gly)
c.257A>G (p.Asp86Gly)
c.461A>G (p.Asp154Gly)
c.329A>G
c.52A>G (p.Ile18Val)
c.464A>G (p.Asp155Gly)
c.283+2053A>G (n.283+2053A>G)
c.173+3298A>G (n.173+3298A>G)
c.240A>G
c.451A>G (p.Ile151Val)
n.1155A>G
 dbSNP
16g.31091259T>GCA395729723VKORC1c.367A>C (p.Ile123Leu)
c.428A>C (p.Asp143Ala)
c.449A>C (p.Asp150Ala)
c.257A>C (p.Asp86Ala)
c.461A>C (p.Asp154Ala)
c.329A>C
c.52A>C (p.Ile18Leu)
c.464A>C (p.Asp155Ala)
c.283+2053A>C (n.283+2053A>C)
c.173+3298A>C (n.173+3298A>C)
c.240A>C
c.451A>C (p.Ile151Leu)
n.1155A>C
16g.31091259T=CA2216889149VKORC1c.367A= (p.Ile123=)
c.428A= (p.Asp143=)
c.449A= (p.Asp150=)
c.257A= (p.Asp86=)
c.461A= (p.Asp154=)
c.329A=
c.52A= (p.Ile18=)
c.464A= (p.Asp155=)
c.283+2053A= (n.283+2053A=)
c.173+3298A= (n.173+3298A=)
c.240A=
c.451A= (p.Ile151=)
n.1155A=
16g.31091260C>ACA395729724VKORC1c.366G>T (p.Trp122Cys)
c.427G>T (p.Asp143Tyr)
c.448G>T (p.Asp150Tyr)
c.256G>T (p.Asp86Tyr)
c.460G>T (p.Asp154Tyr)
c.328G>T
c.51G>T (p.Trp17Cys)
c.463G>T (p.Asp155Tyr)
c.283+2052G>T (n.283+2052G>T)
c.173+3297G>T (n.173+3297G>T)
c.239G>T
c.450G>T (p.Trp150Cys)
n.1154G>T
16g.31091260C=CA2216889156VKORC1c.366G= (p.Trp122=)
c.427G= (p.Asp143=)
c.448G= (p.Asp150=)
c.256G= (p.Asp86=)
c.460G= (p.Asp154=)
c.328G=
c.51G= (p.Trp17=)
c.463G= (p.Asp155=)
c.283+2052G= (n.283+2052G=)
c.173+3297G= (n.173+3297G=)
c.239G=
c.450G= (p.Trp150=)
n.1154G=
16g.31091260C>GCA8021127VKORC1c.366G>C (p.Trp122Cys)
c.427G>C (p.Asp143His)
c.448G>C (p.Asp150His)
c.256G>C (p.Asp86His)
c.460G>C (p.Asp154His)
c.328G>C
c.51G>C (p.Trp17Cys)
c.463G>C (p.Asp155His)
c.283+2052G>C (n.283+2052G>C)
c.173+3297G>C (n.173+3297G>C)
c.239G>C
c.450G>C (p.Trp150Cys)
n.1154G>C
 dbSNP ExAC gnomAD v2 gnomAD v4
16g.31091260C>TCA395729727VKORC1c.366G>A (p.Trp122Ter)
c.427G>A (p.Asp143Asn)
c.448G>A (p.Asp150Asn)
c.256G>A (p.Asp86Asn)
c.460G>A (p.Asp154Asn)
c.328G>A
c.51G>A (p.Trp17Ter)
c.463G>A (p.Asp155Asn)
c.283+2052G>A (n.283+2052G>A)
c.173+3297G>A (n.173+3297G>A)
c.239G>A
c.450G>A (p.Trp150Ter)
n.1154G>A
16g.31091261C>ACA395729732VKORC1c.365G>T (p.Trp122Leu)
c.426G>T (p.Leu142=)
c.447G>T (p.Leu149=)
c.255G>T (p.Leu85=)
c.459G>T (p.Leu153=)
c.327G>T
c.50G>T (p.Trp17Leu)
c.462G>T (p.Leu154=)
c.283+2051G>T (n.283+2051G>T)
c.173+3296G>T (n.173+3296G>T)
c.238G>T
c.449G>T (p.Trp150Leu)
n.1153G>T
16g.31091261C>GCA395729729VKORC1c.365G>C (p.Trp122Ser)
c.426G>C (p.Leu142=)
c.447G>C (p.Leu149=)
c.255G>C (p.Leu85=)
c.459G>C (p.Leu153=)
c.327G>C
c.50G>C (p.Trp17Ser)
c.462G>C (p.Leu154=)
c.283+2051G>C (n.283+2051G>C)
c.173+3296G>C (n.173+3296G>C)
c.238G>C
c.449G>C (p.Trp150Ser)
n.1153G>C
16g.31091261C>TCA395729731VKORC1c.365G>A (p.Trp122Ter)
c.426G>A (p.Leu142=)
c.447G>A (p.Leu149=)
c.255G>A (p.Leu85=)
c.459G>A (p.Leu153=)
c.327G>A
c.50G>A (p.Trp17Ter)
c.462G>A (p.Leu154=)
c.283+2051G>A (n.283+2051G>A)
c.173+3296G>A (n.173+3296G>A)
c.238G>A
c.449G>A (p.Trp150Ter)
n.1153G>A
16g.31091262A>CCA395729733VKORC1c.364T>G (p.Trp122Gly)
c.425T>G (p.Leu142Arg)
c.446T>G (p.Leu149Arg)
c.254T>G (p.Leu85Arg)
c.458T>G (p.Leu153Arg)
c.326T>G
c.49T>G (p.Trp17Gly)
c.461T>G (p.Leu154Arg)
c.283+2050T>G (n.283+2050T>G)
c.173+3295T>G (n.173+3295T>G)
c.237T>G
c.448T>G (p.Trp150Gly)
n.1152T>G
16g.31091262A>GCA395729734VKORC1c.364T>C (p.Trp122Arg)
c.425T>C (p.Leu142Pro)
c.446T>C (p.Leu149Pro)
c.254T>C (p.Leu85Pro)
c.458T>C (p.Leu153Pro)
c.326T>C
c.49T>C (p.Trp17Arg)
c.461T>C (p.Leu154Pro)
c.283+2050T>C (n.283+2050T>C)
c.173+3295T>C (n.173+3295T>C)
c.237T>C
c.448T>C (p.Trp150Arg)
n.1152T>C
16g.31091262A>TCA395729735VKORC1c.364T>A (p.Trp122Arg)
c.425T>A (p.Leu142Gln)
c.446T>A (p.Leu149Gln)
c.254T>A (p.Leu85Gln)
c.458T>A (p.Leu153Gln)
c.326T>A
c.49T>A (p.Trp17Arg)
c.461T>A (p.Leu154Gln)
c.283+2050T>A (n.283+2050T>A)
c.173+3295T>A (n.173+3295T>A)
c.237T>A
c.448T>A (p.Trp150Arg)
n.1152T>A
16g.31091263G>ACA494925969VKORC1c.363C>T (p.Ala121=)
c.424C>T (p.Leu142=)
c.445C>T (p.Leu149=)
c.253C>T (p.Leu85=)
c.457C>T (p.Leu153=)
c.325C>T
c.48C>T (p.Ala16=)
c.460C>T (p.Leu154=)
c.283+2049C>T (n.283+2049C>T)
c.173+3294C>T (n.173+3294C>T)
c.236C>T
c.447C>T (p.Ala149=)
n.1151C>T
 gnomAD v4
16g.31091263G>CCA395729737VKORC1c.363C>G (p.Ala121=)
c.424C>G (p.Leu142Val)
c.445C>G (p.Leu149Val)
c.253C>G (p.Leu85Val)
c.457C>G (p.Leu153Val)
c.325C>G
c.48C>G (p.Ala16=)
c.460C>G (p.Leu154Val)
c.283+2049C>G (n.283+2049C>G)
c.173+3294C>G (n.173+3294C>G)
c.236C>G
c.447C>G (p.Ala149=)
n.1151C>G
16g.31091263G>TCA395729739VKORC1c.363C>A (p.Ala121=)
c.424C>A (p.Leu142Met)
c.445C>A (p.Leu149Met)
c.253C>A (p.Leu85Met)
c.457C>A (p.Leu153Met)
c.325C>A
c.48C>A (p.Ala16=)
c.460C>A (p.Leu154Met)
c.283+2049C>A (n.283+2049C>A)
c.173+3294C>A (n.173+3294C>A)
c.236C>A
c.447C>A (p.Ala149=)
n.1151C>A
16g.31091264G>ACA395729740VKORC1c.362C>T (p.Ala121Val)
c.423C>T (p.Gly141=)
c.444C>T (p.Gly148=)
c.252C>T (p.Gly84=)
c.456C>T (p.Gly152=)
c.324C>T
c.47C>T (p.Ala16Val)
c.459C>T (p.Gly153=)
c.283+2048C>T (n.283+2048C>T)
c.173+3293C>T (n.173+3293C>T)
c.235C>T
c.446C>T (p.Ala149Val)
n.1150C>T
16g.31091264G>CCA395729743VKORC1c.362C>G (p.Ala121Gly)
c.423C>G (p.Gly141=)
c.444C>G (p.Gly148=)
c.252C>G (p.Gly84=)
c.456C>G (p.Gly152=)
c.324C>G
c.47C>G (p.Ala16Gly)
c.459C>G (p.Gly153=)
c.283+2048C>G (n.283+2048C>G)
c.173+3293C>G (n.173+3293C>G)
c.235C>G
c.446C>G (p.Ala149Gly)
n.1150C>G
16g.31091264G>TCA395729742VKORC1c.362C>A (p.Ala121Asp)
c.423C>A (p.Gly141=)
c.444C>A (p.Gly148=)
c.252C>A (p.Gly84=)
c.456C>A (p.Gly152=)
c.324C>A
c.47C>A (p.Ala16Asp)
c.459C>A (p.Gly153=)
c.283+2048C>A (n.283+2048C>A)
c.173+3293C>A (n.173+3293C>A)
c.235C>A
c.446C>A (p.Ala149Asp)
n.1150C>A
16g.31091265C>ACA395729744VKORC1c.361G>T (p.Ala121Ser)
c.422G>T (p.Gly141Val)
c.443G>T (p.Gly148Val)
c.251G>T (p.Gly84Val)
c.455G>T (p.Gly152Val)
c.323G>T
c.46G>T (p.Ala16Ser)
c.458G>T (p.Gly153Val)
c.283+2047G>T (n.283+2047G>T)
c.173+3292G>T (n.173+3292G>T)
c.234G>T
c.445G>T (p.Ala149Ser)
n.1149G>T
16g.31091265C>GCA395729746VKORC1c.361G>C (p.Ala121Pro)
c.422G>C (p.Gly141Ala)
c.443G>C (p.Gly148Ala)
c.251G>C (p.Gly84Ala)
c.455G>C (p.Gly152Ala)
c.323G>C
c.46G>C (p.Ala16Pro)
c.458G>C (p.Gly153Ala)
c.283+2047G>C (n.283+2047G>C)
c.173+3292G>C (n.173+3292G>C)
c.234G>C
c.445G>C (p.Ala149Pro)
n.1149G>C
16g.31091265C>TCA395729747VKORC1c.361G>A (p.Ala121Thr)
c.422G>A (p.Gly141Asp)
c.443G>A (p.Gly148Asp)
c.251G>A (p.Gly84Asp)
c.455G>A (p.Gly152Asp)
c.323G>A
c.46G>A (p.Ala16Thr)
c.458G>A (p.Gly153Asp)
c.283+2047G>A (n.283+2047G>A)
c.173+3292G>A (n.173+3292G>A)
c.234G>A
c.445G>A (p.Ala149Thr)
n.1149G>A
16g.31091266C>ACA395729749VKORC1c.360G>T (p.Leu120=)
c.421G>T (p.Gly141Cys)
c.442G>T (p.Gly148Cys)
c.250G>T (p.Gly84Cys)
c.454G>T (p.Gly152Cys)
c.322G>T
c.45G>T (p.Leu15=)
c.457G>T (p.Gly153Cys)
c.283+2046G>T (n.283+2046G>T)
c.173+3291G>T (n.173+3291G>T)
c.233G>T
c.444G>T (p.Leu148=)
n.1148G>T
16g.31091266C>GCA395729751VKORC1c.360G>C (p.Leu120=)
c.421G>C (p.Gly141Arg)
c.442G>C (p.Gly148Arg)
c.250G>C (p.Gly84Arg)
c.454G>C (p.Gly152Arg)
c.322G>C
c.45G>C (p.Leu15=)
c.457G>C (p.Gly153Arg)
c.283+2046G>C (n.283+2046G>C)
c.173+3291G>C (n.173+3291G>C)
c.233G>C
c.444G>C (p.Leu148=)
n.1148G>C
16g.31091266C>TCA395729753VKORC1c.360G>A (p.Leu120=)
c.421G>A (p.Gly141Ser)
c.442G>A (p.Gly148Ser)
c.250G>A (p.Gly84Ser)
c.454G>A (p.Gly152Ser)
c.322G>A
c.45G>A (p.Leu15=)
c.457G>A (p.Gly153Ser)
c.283+2046G>A (n.283+2046G>A)
c.173+3291G>A (n.173+3291G>A)
c.233G>A
c.444G>A (p.Leu148=)
n.1148G>A
16g.31091267A>CCA395729755VKORC1c.359T>G (p.Leu120Arg)
c.420T>G (p.Pro140=)
c.441T>G (p.Pro147=)
c.249T>G (p.Pro83=)
c.453T>G (p.Pro151=)
c.321T>G
c.44T>G (p.Leu15Arg)
c.456T>G (p.Pro152=)
c.283+2045T>G (n.283+2045T>G)
c.173+3290T>G (n.173+3290T>G)
c.232T>G
c.443T>G (p.Leu148Arg)
n.1147T>G
16g.31091267A>GCA395729757VKORC1c.359T>C (p.Leu120Pro)
c.420T>C (p.Pro140=)
c.441T>C (p.Pro147=)
c.249T>C (p.Pro83=)
c.453T>C (p.Pro151=)
c.321T>C
c.44T>C (p.Leu15Pro)
c.456T>C (p.Pro152=)
c.283+2045T>C (n.283+2045T>C)
c.173+3290T>C (n.173+3290T>C)
c.232T>C
c.443T>C (p.Leu148Pro)
n.1147T>C
16g.31091267A>TCA395729759VKORC1c.359T>A (p.Leu120Gln)
c.420T>A (p.Pro140=)
c.441T>A (p.Pro147=)
c.249T>A (p.Pro83=)
c.453T>A (p.Pro151=)
c.321T>A
c.44T>A (p.Leu15Gln)
c.456T>A (p.Pro152=)
c.283+2045T>A (n.283+2045T>A)
c.173+3290T>A (n.173+3290T>A)
c.232T>A
c.443T>A (p.Leu148Gln)
n.1147T>A
16g.31091268G>ACA8021128VKORC1c.358C>T (p.Leu120=)
c.419C>T (p.Pro140Leu)
c.440C>T (p.Pro147Leu)
c.248C>T (p.Pro83Leu)
c.452C>T (p.Pro151Leu)
c.320C>T
c.43C>T (p.Leu15=)
c.455C>T (p.Pro152Leu)
c.283+2044C>T (n.283+2044C>T)
c.173+3289C>T (n.173+3289C>T)
c.231C>T
c.442C>T (p.Leu148=)
n.1146C>T
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
16g.31091268G>CCA395729761VKORC1c.358C>G (p.Leu120Val)
c.419C>G (p.Pro140Arg)
c.440C>G (p.Pro147Arg)
c.248C>G (p.Pro83Arg)
c.452C>G (p.Pro151Arg)
c.320C>G
c.43C>G (p.Leu15Val)
c.455C>G (p.Pro152Arg)
c.283+2044C>G (n.283+2044C>G)
c.173+3289C>G (n.173+3289C>G)
c.231C>G
c.442C>G (p.Leu148Val)
n.1146C>G
16g.31091268G=CA2216889164VKORC1c.358C= (p.Leu120=)
c.419C= (p.Pro140=)
c.440C= (p.Pro147=)
c.248C= (p.Pro83=)
c.452C= (p.Pro151=)
c.320C=
c.43C= (p.Leu15=)
c.455C= (p.Pro152=)
c.283+2044C= (n.283+2044C=)
c.173+3289C= (n.173+3289C=)
c.231C=
c.442C= (p.Leu148=)
n.1146C=
16g.31091268G>TCA395729762VKORC1c.358C>A (p.Leu120Met)
c.419C>A (p.Pro140His)
c.440C>A (p.Pro147His)
c.248C>A (p.Pro83His)
c.452C>A (p.Pro151His)
c.320C>A
c.43C>A (p.Leu15Met)
c.455C>A (p.Pro152His)
c.283+2044C>A (n.283+2044C>A)
c.173+3289C>A (n.173+3289C>A)
c.231C>A
c.442C>A (p.Leu148Met)
n.1146C>A
16g.31091269G>ACA395729766VKORC1c.357C>T (p.Tyr119=)
c.418C>T (p.Pro140Ser)
c.439C>T (p.Pro147Ser)
c.247C>T (p.Pro83Ser)
c.451C>T (p.Pro151Ser)
c.319C>T
c.42C>T (p.Tyr14=)
c.454C>T (p.Pro152Ser)
c.283+2043C>T (n.283+2043C>T)
c.173+3288C>T (n.173+3288C>T)
c.230C>T
c.441C>T (p.Tyr147=)
n.1145C>T
 dbSNP gnomAD v4
16g.31091269G>CCA395729764VKORC1c.357C>G (p.Tyr119Ter)
c.418C>G (p.Pro140Ala)
c.439C>G (p.Pro147Ala)
c.247C>G (p.Pro83Ala)
c.451C>G (p.Pro151Ala)
c.319C>G
c.42C>G (p.Tyr14Ter)
c.454C>G (p.Pro152Ala)
c.283+2043C>G (n.283+2043C>G)
c.173+3288C>G (n.173+3288C>G)
c.230C>G
c.441C>G (p.Tyr147Ter)
n.1145C>G
16g.31091269G=CA2216889168VKORC1c.357C= (p.Tyr119=)
c.418C= (p.Pro140=)
c.439C= (p.Pro147=)
c.247C= (p.Pro83=)
c.451C= (p.Pro151=)
c.319C=
c.42C= (p.Tyr14=)
c.454C= (p.Pro152=)
c.283+2043C= (n.283+2043C=)
c.173+3288C= (n.173+3288C=)
c.230C=
c.441C= (p.Tyr147=)
n.1145C=
16g.31091269G>TCA395729765VKORC1c.357C>A (p.Tyr119Ter)
c.418C>A (p.Pro140Thr)
c.439C>A (p.Pro147Thr)
c.247C>A (p.Pro83Thr)
c.451C>A (p.Pro151Thr)
c.319C>A
c.42C>A (p.Tyr14Ter)
c.454C>A (p.Pro152Thr)
c.283+2043C>A (n.283+2043C>A)
c.173+3288C>A (n.173+3288C>A)
c.230C>A
c.441C>A (p.Tyr147Ter)
n.1145C>A
16g.31091270T>ACA395729768VKORC1c.356A>T (p.Tyr119Phe)
c.417A>T (p.Leu139=)
c.438A>T (p.Leu146=)
c.246A>T (p.Leu82=)
c.450A>T (p.Leu150=)
c.318A>T
c.41A>T (p.Tyr14Phe)
c.453A>T (p.Leu151=)
c.283+2042A>T (n.283+2042A>T)
c.173+3287A>T (n.173+3287A>T)
c.229A>T
c.440A>T (p.Tyr147Phe)
n.1144A>T
16g.31091270T>CCA395729770VKORC1c.356A>G (p.Tyr119Cys)
c.417A>G (p.Leu139=)
c.438A>G (p.Leu146=)
c.246A>G (p.Leu82=)
c.450A>G (p.Leu150=)
c.318A>G
c.41A>G (p.Tyr14Cys)
c.453A>G (p.Leu151=)
c.283+2042A>G (n.283+2042A>G)
c.173+3287A>G (n.173+3287A>G)
c.229A>G
c.440A>G (p.Tyr147Cys)
n.1144A>G
16g.31091270T>GCA395729772VKORC1c.356A>C (p.Tyr119Ser)
c.417A>C (p.Leu139=)
c.438A>C (p.Leu146=)
c.246A>C (p.Leu82=)
c.450A>C (p.Leu150=)
c.318A>C
c.41A>C (p.Tyr14Ser)
c.453A>C (p.Leu151=)
c.283+2042A>C (n.283+2042A>C)
c.173+3287A>C (n.173+3287A>C)
c.229A>C
c.440A>C (p.Tyr147Ser)
n.1144A>C
16g.31091271A=CA2216889171VKORC1c.355T= (p.Tyr119=)
c.416T= (p.Leu139=)
c.437T= (p.Leu146=)
c.245T= (p.Leu82=)
c.449T= (p.Leu150=)
c.317T=
c.40T= (p.Tyr14=)
c.452T= (p.Leu151=)
c.283+2041T= (n.283+2041T=)
c.173+3286T= (n.173+3286T=)
c.228T=
c.439T= (p.Tyr147=)
n.1143T=
16g.31091271A>CCA395729774VKORC1c.355T>G (p.Tyr119Asp)
c.416T>G (p.Leu139Arg)
c.437T>G (p.Leu146Arg)
c.245T>G (p.Leu82Arg)
c.449T>G (p.Leu150Arg)
c.317T>G
c.40T>G (p.Tyr14Asp)
c.452T>G (p.Leu151Arg)
c.283+2041T>G (n.283+2041T>G)
c.173+3286T>G (n.173+3286T>G)
c.228T>G
c.439T>G (p.Tyr147Asp)
n.1143T>G
16g.31091271A>GCA395729775VKORC1c.355T>C (p.Tyr119His)
c.416T>C (p.Leu139Pro)
c.437T>C (p.Leu146Pro)
c.245T>C (p.Leu82Pro)
c.449T>C (p.Leu150Pro)
c.317T>C
c.40T>C (p.Tyr14His)
c.452T>C (p.Leu151Pro)
c.283+2041T>C (n.283+2041T>C)
c.173+3286T>C (n.173+3286T>C)
c.228T>C
c.439T>C (p.Tyr147His)
n.1143T>C
16g.31091271A>TCA8021129VKORC1c.355T>A (p.Tyr119Asn)
c.416T>A (p.Leu139Gln)
c.437T>A (p.Leu146Gln)
c.245T>A (p.Leu82Gln)
c.449T>A (p.Leu150Gln)
c.317T>A
c.40T>A (p.Tyr14Asn)
c.452T>A (p.Leu151Gln)
c.283+2041T>A (n.283+2041T>A)
c.173+3286T>A (n.173+3286T>A)
c.228T>A
c.439T>A (p.Tyr147Asn)
n.1143T>A
 dbSNP ExAC gnomAD v2 gnomAD v4
16g.31091272G>ACA494925976VKORC1c.354C>T (p.Val118=)
c.415C>T (p.Leu139=)
c.436C>T (p.Leu146=)
c.244C>T (p.Leu82=)
c.448C>T (p.Leu150=)
c.316C>T
c.39C>T (p.Val13=)
c.451C>T (p.Leu151=)
c.283+2040C>T (n.283+2040C>T)
c.173+3285C>T (n.173+3285C>T)
c.227C>T
c.438C>T (p.Val146=)
n.1142C>T
16g.31091272G>CCA395729779VKORC1c.354C>G (p.Val118=)
c.415C>G (p.Leu139Val)
c.436C>G (p.Leu146Val)
c.244C>G (p.Leu82Val)
c.448C>G (p.Leu150Val)
c.316C>G
c.39C>G (p.Val13=)
c.451C>G (p.Leu151Val)
c.283+2040C>G (n.283+2040C>G)
c.173+3285C>G (n.173+3285C>G)
c.227C>G
c.438C>G (p.Val146=)
n.1142C>G
 dbSNP
16g.31091272G=CA2216889176VKORC1c.354C= (p.Val118=)
c.415C= (p.Leu139=)
c.436C= (p.Leu146=)
c.244C= (p.Leu82=)
c.448C= (p.Leu150=)
c.316C=
c.39C= (p.Val13=)
c.451C= (p.Leu151=)
c.283+2040C= (n.283+2040C=)
c.173+3285C= (n.173+3285C=)
c.227C=
c.438C= (p.Val146=)
n.1142C=
16g.31091272G>TCA395729777VKORC1c.354C>A (p.Val118=)
c.415C>A (p.Leu139Ile)
c.436C>A (p.Leu146Ile)
c.244C>A (p.Leu82Ile)
c.448C>A (p.Leu150Ile)
c.316C>A
c.39C>A (p.Val13=)
c.451C>A (p.Leu151Ile)
c.283+2040C>A (n.283+2040C>A)
c.173+3285C>A (n.173+3285C>A)
c.227C>A
c.438C>A (p.Val146=)
n.1142C>A
16g.31091273A>CCA395729781VKORC1c.353T>G (p.Val118Gly)
c.414T>G (p.Cys138Trp)
c.435T>G (p.Cys145Trp)
c.243T>G (p.Cys81Trp)
c.447T>G (p.Cys149Trp)
c.315T>G
c.38T>G (p.Val13Gly)
c.450T>G (p.Cys150Trp)
c.283+2039T>G (n.283+2039T>G)
c.173+3284T>G (n.173+3284T>G)
c.226T>G
c.437T>G (p.Val146Gly)
n.1141T>G
16g.31091273A>GCA395729782VKORC1c.353T>C (p.Val118Ala)
c.414T>C (p.Cys138=)
c.435T>C (p.Cys145=)
c.243T>C (p.Cys81=)
c.447T>C (p.Cys149=)
c.315T>C
c.38T>C (p.Val13Ala)
c.450T>C (p.Cys150=)
c.283+2039T>C (n.283+2039T>C)
c.173+3284T>C (n.173+3284T>C)
c.226T>C
c.437T>C (p.Val146Ala)
n.1141T>C
 gnomAD v4
16g.31091273A>TCA395729784VKORC1c.353T>A (p.Val118Asp)
c.414T>A (p.Cys138Ter)
c.435T>A (p.Cys145Ter)
c.243T>A (p.Cys81Ter)
c.447T>A (p.Cys149Ter)
c.315T>A
c.38T>A (p.Val13Asp)
c.450T>A (p.Cys150Ter)
c.283+2039T>A (n.283+2039T>A)
c.173+3284T>A (n.173+3284T>A)
c.226T>A
c.437T>A (p.Val146Asp)
n.1141T>A
16g.31091274C>ACA395729786VKORC1c.352G>T (p.Val118Phe)
c.413G>T (p.Cys138Phe)
c.434G>T (p.Cys145Phe)
c.242G>T (p.Cys81Phe)
c.446G>T (p.Cys149Phe)
c.314G>T
c.37G>T (p.Val13Phe)
c.449G>T (p.Cys150Phe)
c.283+2038G>T (n.283+2038G>T)
c.173+3283G>T (n.173+3283G>T)
c.225G>T
c.436G>T (p.Val146Phe)
n.1140G>T
 dbSNP gnomAD v3 gnomAD v4
16g.31091274C=CA2216889180VKORC1c.352G= (p.Val118=)
c.413G= (p.Cys138=)
c.434G= (p.Cys145=)
c.242G= (p.Cys81=)
c.446G= (p.Cys149=)
c.314G=
c.37G= (p.Val13=)
c.449G= (p.Cys150=)
c.283+2038G= (n.283+2038G=)
c.173+3283G= (n.173+3283G=)
c.225G=
c.436G= (p.Val146=)
n.1140G=
16g.31091274C>GCA8021130VKORC1c.352G>C (p.Val118Leu)
c.413G>C (p.Cys138Ser)
c.434G>C (p.Cys145Ser)
c.242G>C (p.Cys81Ser)
c.446G>C (p.Cys149Ser)
c.314G>C
c.37G>C (p.Val13Leu)
c.449G>C (p.Cys150Ser)
c.283+2038G>C (n.283+2038G>C)
c.173+3283G>C (n.173+3283G>C)
c.225G>C
c.436G>C (p.Val146Leu)
n.1140G>C
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
16g.31091274C>TCA280619957VKORC1c.352G>A (p.Val118Ile)
c.413G>A (p.Cys138Tyr)
c.434G>A (p.Cys145Tyr)
c.242G>A (p.Cys81Tyr)
c.446G>A (p.Cys149Tyr)
c.314G>A
c.37G>A (p.Val13Ile)
c.449G>A (p.Cys150Tyr)
c.283+2038G>A (n.283+2038G>A)
c.173+3283G>A (n.173+3283G>A)
c.225G>A
c.436G>A (p.Val146Ile)
n.1140G>A
 dbSNP gnomAD v4
16g.31091275A>CCA395729794VKORC1c.351T>G (p.Ser117=)
c.412T>G (p.Cys138Gly)
c.433T>G (p.Cys145Gly)
c.241T>G (p.Cys81Gly)
c.445T>G (p.Cys149Gly)
c.313T>G
c.36T>G (p.Ser12=)
c.448T>G (p.Cys150Gly)
c.283+2037T>G (n.283+2037T>G)
c.173+3282T>G (n.173+3282T>G)
c.224T>G
c.435T>G (p.Ser145=)
n.1139T>G
16g.31091275A>GCA395729789VKORC1c.351T>C (p.Ser117=)
c.412T>C (p.Cys138Arg)
c.433T>C (p.Cys145Arg)
c.241T>C (p.Cys81Arg)
c.445T>C (p.Cys149Arg)
c.313T>C
c.36T>C (p.Ser12=)
c.448T>C (p.Cys150Arg)
c.283+2037T>C (n.283+2037T>C)
c.173+3282T>C (n.173+3282T>C)
c.224T>C
c.435T>C (p.Ser145=)
n.1139T>C
16g.31091275A>TCA395729791VKORC1c.351T>A (p.Ser117=)
c.412T>A (p.Cys138Ser)
c.433T>A (p.Cys145Ser)
c.241T>A (p.Cys81Ser)
c.445T>A (p.Cys149Ser)
c.313T>A
c.36T>A (p.Ser12=)
c.448T>A (p.Cys150Ser)
c.283+2037T>A (n.283+2037T>A)
c.173+3282T>A (n.173+3282T>A)
c.224T>A
c.435T>A (p.Ser145=)
n.1139T>A
16g.31091276G>ACA395729795VKORC1c.350C>T (p.Ser117Phe)
c.411C>T (p.Phe137=)
c.432C>T (p.Phe144=)
c.240C>T (p.Phe80=)
c.444C>T (p.Phe148=)
c.312C>T
c.35C>T (p.Ser12Phe)
c.447C>T (p.Phe149=)
c.283+2036C>T (n.283+2036C>T)
c.173+3281C>T (n.173+3281C>T)
c.223C>T
c.434C>T (p.Ser145Phe)
n.1138C>T
16g.31091276G>CCA395729796VKORC1c.350C>G (p.Ser117Cys)
c.411C>G (p.Phe137Leu)
c.432C>G (p.Phe144Leu)
c.240C>G (p.Phe80Leu)
c.444C>G (p.Phe148Leu)
c.312C>G
c.35C>G (p.Ser12Cys)
c.447C>G (p.Phe149Leu)
c.283+2036C>G (n.283+2036C>G)
c.173+3281C>G (n.173+3281C>G)
c.223C>G
c.434C>G (p.Ser145Cys)
n.1138C>G
16g.31091276G>TCA395729798VKORC1c.350C>A (p.Ser117Tyr)
c.411C>A (p.Phe137Leu)
c.432C>A (p.Phe144Leu)
c.240C>A (p.Phe80Leu)
c.444C>A (p.Phe148Leu)
c.312C>A
c.35C>A (p.Ser12Tyr)
c.447C>A (p.Phe149Leu)
c.283+2036C>A (n.283+2036C>A)
c.173+3281C>A (n.173+3281C>A)
c.223C>A
c.434C>A (p.Ser145Tyr)
n.1138C>A
16g.31091277A>CCA395729800VKORC1c.349T>G (p.Ser117Ala)
c.410T>G (p.Phe137Cys)
c.431T>G (p.Phe144Cys)
c.239T>G (p.Phe80Cys)
c.443T>G (p.Phe148Cys)
c.311T>G
c.34T>G (p.Ser12Ala)
c.446T>G (p.Phe149Cys)
c.283+2035T>G (n.283+2035T>G)
c.173+3280T>G (n.173+3280T>G)
c.222T>G
c.433T>G (p.Ser145Ala)
n.1137T>G
16g.31091277A>GCA395729802VKORC1c.349T>C (p.Ser117Pro)
c.410T>C (p.Phe137Ser)
c.431T>C (p.Phe144Ser)
c.239T>C (p.Phe80Ser)
c.443T>C (p.Phe148Ser)
c.311T>C
c.34T>C (p.Ser12Pro)
c.446T>C (p.Phe149Ser)
c.283+2035T>C (n.283+2035T>C)
c.173+3280T>C (n.173+3280T>C)
c.222T>C
c.433T>C (p.Ser145Pro)
n.1137T>C
16g.31091277A>TCA395729804VKORC1c.349T>A (p.Ser117Thr)
c.410T>A (p.Phe137Tyr)
c.431T>A (p.Phe144Tyr)
c.239T>A (p.Phe80Tyr)
c.443T>A (p.Phe148Tyr)
c.311T>A
c.34T>A (p.Ser12Thr)
c.446T>A (p.Phe149Tyr)
c.283+2035T>A (n.283+2035T>A)
c.173+3280T>A (n.173+3280T>A)
c.222T>A
c.433T>A (p.Ser145Thr)
n.1137T>A
16g.31091278A>CCA395729806VKORC1c.348T>G (p.Gly116=)
c.409T>G (p.Phe137Val)
c.430T>G (p.Phe144Val)
c.238T>G (p.Phe80Val)
c.442T>G (p.Phe148Val)
c.310T>G
c.33T>G (p.Gly11=)
c.445T>G (p.Phe149Val)
c.283+2034T>G (n.283+2034T>G)
c.173+3279T>G (n.173+3279T>G)
c.221T>G
c.432T>G (p.Gly144=)
n.1136T>G
 gnomAD v4
16g.31091278A>GCA395729807VKORC1c.348T>C (p.Gly116=)
c.409T>C (p.Phe137Leu)
c.430T>C (p.Phe144Leu)
c.238T>C (p.Phe80Leu)
c.442T>C (p.Phe148Leu)
c.310T>C
c.33T>C (p.Gly11=)
c.445T>C (p.Phe149Leu)
c.283+2034T>C (n.283+2034T>C)
c.173+3279T>C (n.173+3279T>C)
c.221T>C
c.432T>C (p.Gly144=)
n.1136T>C
16g.31091278A>TCA395729809VKORC1c.348T>A (p.Gly116=)
c.409T>A (p.Phe137Ile)
c.430T>A (p.Phe144Ile)
c.238T>A (p.Phe80Ile)
c.442T>A (p.Phe148Ile)
c.310T>A
c.33T>A (p.Gly11=)
c.445T>A (p.Phe149Ile)
c.283+2034T>A (n.283+2034T>A)
c.173+3279T>A (n.173+3279T>A)
c.221T>A
c.432T>A (p.Gly144=)
n.1136T>A
16g.31091279C>ACA395729812VKORC1c.347G>T (p.Gly116Val)
c.408G>T (p.Trp136Cys)
c.429G>T (p.Trp143Cys)
c.237G>T (p.Trp79Cys)
c.441G>T (p.Trp147Cys)
c.309G>T
c.32G>T (p.Gly11Val)
c.444G>T (p.Trp148Cys)
c.283+2033G>T (n.283+2033G>T)
c.173+3278G>T (n.173+3278G>T)
c.220G>T
c.431G>T (p.Gly144Val)
n.1135G>T
16g.31091279C>GCA395729813VKORC1c.347G>C (p.Gly116Ala)
c.408G>C (p.Trp136Cys)
c.429G>C (p.Trp143Cys)
c.237G>C (p.Trp79Cys)
c.441G>C (p.Trp147Cys)
c.309G>C
c.32G>C (p.Gly11Ala)
c.444G>C (p.Trp148Cys)
c.283+2033G>C (n.283+2033G>C)
c.173+3278G>C (n.173+3278G>C)
c.220G>C
c.431G>C (p.Gly144Ala)
n.1135G>C
16g.31091279C>TCA395729814VKORC1c.347G>A (p.Gly116Asp)
c.408G>A (p.Trp136Ter)
c.429G>A (p.Trp143Ter)
c.237G>A (p.Trp79Ter)
c.441G>A (p.Trp147Ter)
c.309G>A
c.32G>A (p.Gly11Asp)
c.444G>A (p.Trp148Ter)
c.283+2033G>A (n.283+2033G>A)
c.173+3278G>A (n.173+3278G>A)
c.220G>A
c.431G>A (p.Gly144Asp)
n.1135G>A
16g.31091280C>ACA395729816VKORC1c.346G>T (p.Gly116Cys)
c.407G>T (p.Trp136Leu)
c.428G>T (p.Trp143Leu)
c.236G>T (p.Trp79Leu)
c.440G>T (p.Trp147Leu)
c.308G>T
c.31G>T (p.Gly11Cys)
c.443G>T (p.Trp148Leu)
c.283+2032G>T (n.283+2032G>T)
c.173+3277G>T (n.173+3277G>T)
c.219G>T
c.430G>T (p.Gly144Cys)
n.1134G>T
16g.31091280C>GCA395729820VKORC1c.346G>C (p.Gly116Arg)
c.407G>C (p.Trp136Ser)
c.428G>C (p.Trp143Ser)
c.236G>C (p.Trp79Ser)
c.440G>C (p.Trp147Ser)
c.308G>C
c.31G>C (p.Gly11Arg)
c.443G>C (p.Trp148Ser)
c.283+2032G>C (n.283+2032G>C)
c.173+3277G>C (n.173+3277G>C)
c.219G>C
c.430G>C (p.Gly144Arg)
n.1134G>C
16g.31091280C>TCA395729818VKORC1c.346G>A (p.Gly116Ser)
c.407G>A (p.Trp136Ter)
c.428G>A (p.Trp143Ter)
c.236G>A (p.Trp79Ter)
c.440G>A (p.Trp147Ter)
c.308G>A
c.31G>A (p.Gly11Ser)
c.443G>A (p.Trp148Ter)
c.283+2032G>A (n.283+2032G>A)
c.173+3277G>A (n.173+3277G>A)
c.219G>A
c.430G>A (p.Gly144Ser)
n.1134G>A
 gnomAD v4
16g.31091281A=CA2216889191VKORC1c.345T= (p.Ala115=)
c.406T= (p.Trp136=)
c.427T= (p.Trp143=)
c.235T= (p.Trp79=)
c.439T= (p.Trp147=)
c.307T=
c.30T= (p.Ala10=)
c.442T= (p.Trp148=)
c.283+2031T= (n.283+2031T=)
c.173+3276T= (n.173+3276T=)
c.218T=
c.429T= (p.Ala143=)
n.1133T=
16g.31091281A>CCA395729821VKORC1c.345T>G (p.Ala115=)
c.406T>G (p.Trp136Gly)
c.427T>G (p.Trp143Gly)
c.235T>G (p.Trp79Gly)
c.439T>G (p.Trp147Gly)
c.307T>G
c.30T>G (p.Ala10=)
c.442T>G (p.Trp148Gly)
c.283+2031T>G (n.283+2031T>G)
c.173+3276T>G (n.173+3276T>G)
c.218T>G
c.429T>G (p.Ala143=)
n.1133T>G
16g.31091281A>GCA395729822VKORC1c.345T>C (p.Ala115=)
c.406T>C (p.Trp136Arg)
c.427T>C (p.Trp143Arg)
c.235T>C (p.Trp79Arg)
c.439T>C (p.Trp147Arg)
c.307T>C
c.30T>C (p.Ala10=)
c.442T>C (p.Trp148Arg)
c.283+2031T>C (n.283+2031T>C)
c.173+3276T>C (n.173+3276T>C)
c.218T>C
c.429T>C (p.Ala143=)
n.1133T>C
 dbSNP gnomAD v2
16g.31091281A>TCA395729824VKORC1c.345T>A (p.Ala115=)
c.406T>A (p.Trp136Arg)
c.427T>A (p.Trp143Arg)
c.235T>A (p.Trp79Arg)
c.439T>A (p.Trp147Arg)
c.307T>A
c.30T>A (p.Ala10=)
c.442T>A (p.Trp148Arg)
c.283+2031T>A (n.283+2031T>A)
c.173+3276T>A (n.173+3276T>A)
c.218T>A
c.429T>A (p.Ala143=)
n.1133T>A
16g.31091282G>ACA8021131VKORC1c.344C>T (p.Ala115Val)
c.405C>T (p.Arg135=)
c.426C>T (p.Arg142=)
c.234C>T (p.Arg78=)
c.438C>T (p.Arg146=)
c.306C>T
c.29C>T (p.Ala10Val)
c.441C>T (p.Arg147=)
c.283+2030C>T (n.283+2030C>T)
c.173+3275C>T (n.173+3275C>T)
c.217C>T
c.428C>T (p.Ala143Val)
n.1132C>T
 dbSNP ExAC gnomAD v2 gnomAD v4
16g.31091282G>CCA8021132VKORC1c.344C>G (p.Ala115Gly)
c.405C>G (p.Arg135=)
c.426C>G (p.Arg142=)
c.234C>G (p.Arg78=)
c.438C>G (p.Arg146=)
c.306C>G
c.29C>G (p.Ala10Gly)
c.441C>G (p.Arg147=)
c.283+2030C>G (n.283+2030C>G)
c.173+3275C>G (n.173+3275C>G)
c.217C>G
c.428C>G (p.Ala143Gly)
n.1132C>G
 dbSNP ExAC gnomAD v2 gnomAD v4
16g.31091282G=CA2216889196VKORC1c.344C= (p.Ala115=)
c.405C= (p.Arg135=)
c.426C= (p.Arg142=)
c.234C= (p.Arg78=)
c.438C= (p.Arg146=)
c.306C=
c.29C= (p.Ala10=)
c.441C= (p.Arg147=)
c.283+2030C= (n.283+2030C=)
c.173+3275C= (n.173+3275C=)
c.217C=
c.428C= (p.Ala143=)
n.1132C=
16g.31091282G>TCA395729827VKORC1c.344C>A (p.Ala115Asp)
c.405C>A (p.Arg135=)
c.426C>A (p.Arg142=)
c.234C>A (p.Arg78=)
c.438C>A (p.Arg146=)
c.306C>A
c.29C>A (p.Ala10Asp)
c.441C>A (p.Arg147=)
c.283+2030C>A (n.283+2030C>A)
c.173+3275C>A (n.173+3275C>A)
c.217C>A
c.428C>A (p.Ala143Asp)
n.1132C>A
16g.31091283C>ACA395729833VKORC1c.343G>T (p.Ala115Ser)
c.404G>T (p.Arg135Leu)
c.425G>T (p.Arg142Leu)
c.233G>T (p.Arg78Leu)
c.437G>T (p.Arg146Leu)
c.305G>T
c.28G>T (p.Ala10Ser)
c.440G>T (p.Arg147Leu)
c.283+2029G>T (n.283+2029G>T)
c.173+3274G>T (n.173+3274G>T)
c.216G>T
c.427G>T (p.Ala143Ser)
n.1131G>T
16g.31091283C=CA2216889203VKORC1c.343G= (p.Ala115=)
c.404G= (p.Arg135=)
c.425G= (p.Arg142=)
c.233G= (p.Arg78=)
c.437G= (p.Arg146=)
c.305G=
c.28G= (p.Ala10=)
c.440G= (p.Arg147=)
c.283+2029G= (n.283+2029G=)
c.173+3274G= (n.173+3274G=)
c.216G=
c.427G= (p.Ala143=)
n.1131G=
16g.31091283C>GCA395729832VKORC1c.343G>C (p.Ala115Pro)
c.404G>C (p.Arg135Pro)
c.425G>C (p.Arg142Pro)
c.233G>C (p.Arg78Pro)
c.437G>C (p.Arg146Pro)
c.305G>C
c.28G>C (p.Ala10Pro)
c.440G>C (p.Arg147Pro)
c.283+2029G>C (n.283+2029G>C)
c.173+3274G>C (n.173+3274G>C)
c.216G>C
c.427G>C (p.Ala143Pro)
n.1131G>C
16g.31091283C>TCA395729830VKORC1c.343G>A (p.Ala115Thr)
c.404G>A (p.Arg135His)
c.425G>A (p.Arg142His)
c.233G>A (p.Arg78His)
c.437G>A (p.Arg146His)
c.305G>A
c.28G>A (p.Ala10Thr)
c.440G>A (p.Arg147His)
c.283+2029G>A (n.283+2029G>A)
c.173+3274G>A (n.173+3274G>A)
c.216G>A
c.427G>A (p.Ala143Thr)
n.1131G>A
 dbSNP gnomAD v4
16g.31091284G>ACA395729835VKORC1c.342C>T (p.Leu114=)
c.403C>T (p.Arg135Cys)
c.424C>T (p.Arg142Cys)
c.232C>T (p.Arg78Cys)
c.436C>T (p.Arg146Cys)
c.304C>T
c.27C>T (p.Leu9=)
c.439C>T (p.Arg147Cys)
c.283+2028C>T (n.283+2028C>T)
c.173+3273C>T (n.173+3273C>T)
c.215C>T
c.426C>T (p.Leu142=)
n.1130C>T
 dbSNP gnomAD v4
16g.31091284G>CCA395729837VKORC1c.342C>G (p.Leu114=)
c.403C>G (p.Arg135Gly)
c.424C>G (p.Arg142Gly)
c.232C>G (p.Arg78Gly)
c.436C>G (p.Arg146Gly)
c.304C>G
c.27C>G (p.Leu9=)
c.439C>G (p.Arg147Gly)
c.283+2028C>G (n.283+2028C>G)
c.173+3273C>G (n.173+3273C>G)
c.215C>G
c.426C>G (p.Leu142=)
n.1130C>G
 ClinVar dbSNP
16g.31091284G=CA2216889204VKORC1c.342C= (p.Leu114=)
c.403C= (p.Arg135=)
c.424C= (p.Arg142=)
c.232C= (p.Arg78=)
c.436C= (p.Arg146=)
c.304C=
c.27C= (p.Leu9=)
c.439C= (p.Arg147=)
c.283+2028C= (n.283+2028C=)
c.173+3273C= (n.173+3273C=)
c.215C=
c.426C= (p.Leu142=)
n.1130C=
16g.31091284G>TCA395729839VKORC1c.342C>A (p.Leu114=)
c.403C>A (p.Arg135Ser)
c.424C>A (p.Arg142Ser)
c.232C>A (p.Arg78Ser)
c.436C>A (p.Arg146Ser)
c.304C>A
c.27C>A (p.Leu9=)
c.439C>A (p.Arg147Ser)
c.283+2028C>A (n.283+2028C>A)
c.173+3273C>A (n.173+3273C>A)
c.215C>A
c.426C>A (p.Leu142=)
n.1130C>A
16g.31091288_31091289delCA2575974951VKORC1c.341_342del (p.Leu114ArgfsTer16)
c.402_403del (p.Arg135LeufsTer29)
c.423_424del (p.Arg142LeufsTer29)
c.231_232del (p.Arg78LeufsTer29)
c.435_436del (p.Arg146LeufsTer29)
c.303_304del
c.26_27del (p.Leu9ArgfsTer16)
c.438_439del (p.Arg147LeufsTer29)
c.283+2027_283+2028del (n.283+2027_283+2028del)
c.173+3272_173+3273del (n.173+3272_173+3273del)
c.214_215del
c.425_426del (p.Leu142ArgfsTer16)
n.1129_1130del
16g.31091285A>CCA395729841VKORC1c.341T>G (p.Leu114Arg)
c.402T>G (p.Ser134=)
c.423T>G (p.Ser141=)
c.231T>G (p.Ser77=)
c.435T>G (p.Ser145=)
c.303T>G
c.26T>G (p.Leu9Arg)
c.438T>G (p.Ser146=)
c.283+2027T>G (n.283+2027T>G)
c.173+3272T>G (n.173+3272T>G)
c.214T>G
c.425T>G (p.Leu142Arg)
n.1129T>G
16g.31091285A>GCA395729843VKORC1c.341T>C (p.Leu114Pro)
c.402T>C (p.Ser134=)
c.423T>C (p.Ser141=)
c.231T>C (p.Ser77=)
c.435T>C (p.Ser145=)
c.303T>C
c.26T>C (p.Leu9Pro)
c.438T>C (p.Ser146=)
c.283+2027T>C (n.283+2027T>C)
c.173+3272T>C (n.173+3272T>C)
c.214T>C
c.425T>C (p.Leu142Pro)
n.1129T>C
16g.31091285A>TCA395729845VKORC1c.341T>A (p.Leu114His)
c.402T>A (p.Ser134=)
c.423T>A (p.Ser141=)
c.231T>A (p.Ser77=)
c.435T>A (p.Ser145=)
c.303T>A
c.26T>A (p.Leu9His)
c.438T>A (p.Ser146=)
c.283+2027T>A (n.283+2027T>A)
c.173+3272T>A (n.173+3272T>A)
c.214T>A
c.425T>A (p.Leu142His)
n.1129T>A
16g.31091286G>ACA395729846VKORC1c.340C>T (p.Leu114Phe)
c.401C>T (p.Ser134Phe)
c.422C>T (p.Ser141Phe)
c.230C>T (p.Ser77Phe)
c.434C>T (p.Ser145Phe)
c.302C>T
c.25C>T (p.Leu9Phe)
c.437C>T (p.Ser146Phe)
c.283+2026C>T (n.283+2026C>T)
c.173+3271C>T (n.173+3271C>T)
c.213C>T
c.424C>T (p.Leu142Phe)
n.1128C>T
16g.31091286G>CCA395729850VKORC1c.340C>G (p.Leu114Val)
c.401C>G (p.Ser134Cys)
c.422C>G (p.Ser141Cys)
c.230C>G (p.Ser77Cys)
c.434C>G (p.Ser145Cys)
c.302C>G
c.25C>G (p.Leu9Val)
c.437C>G (p.Ser146Cys)
c.283+2026C>G (n.283+2026C>G)
c.173+3271C>G (n.173+3271C>G)
c.213C>G
c.424C>G (p.Leu142Val)
n.1128C>G
16g.31091286G>TCA395729848VKORC1c.340C>A (p.Leu114Ile)
c.401C>A (p.Ser134Tyr)
c.422C>A (p.Ser141Tyr)
c.230C>A (p.Ser77Tyr)
c.434C>A (p.Ser145Tyr)
c.302C>A
c.25C>A (p.Leu9Ile)
c.437C>A (p.Ser146Tyr)
c.283+2026C>A (n.283+2026C>A)
c.173+3271C>A (n.173+3271C>A)
c.213C>A
c.424C>A (p.Leu142Ile)
n.1128C>A
16g.31091287A=CA2216889209VKORC1c.339T= (p.Ser113=)
c.400T= (p.Ser134=)
c.421T= (p.Ser141=)
c.229T= (p.Ser77=)
c.433T= (p.Ser145=)
c.301T=
c.24T= (p.Ser8=)
c.436T= (p.Ser146=)
c.283+2025T= (n.283+2025T=)
c.173+3270T= (n.173+3270T=)
c.212T=
c.423T= (p.Ser141=)
n.1127T=
16g.31091287A>CCA395729852VKORC1c.339T>G (p.Ser113=)
c.400T>G (p.Ser134Ala)
c.421T>G (p.Ser141Ala)
c.229T>G (p.Ser77Ala)
c.433T>G (p.Ser145Ala)
c.301T>G
c.24T>G (p.Ser8=)
c.436T>G (p.Ser146Ala)
c.283+2025T>G (n.283+2025T>G)
c.173+3270T>G (n.173+3270T>G)
c.212T>G
c.423T>G (p.Ser141=)
n.1127T>G
16g.31091287A>GCA395729854VKORC1c.339T>C (p.Ser113=)
c.400T>C (p.Ser134Pro)
c.421T>C (p.Ser141Pro)
c.229T>C (p.Ser77Pro)
c.433T>C (p.Ser145Pro)
c.301T>C
c.24T>C (p.Ser8=)
c.436T>C (p.Ser146Pro)
c.283+2025T>C (n.283+2025T>C)
c.173+3270T>C (n.173+3270T>C)
c.212T>C
c.423T>C (p.Ser141=)
n.1127T>C
 dbSNP gnomAD v4
16g.31091287A>TCA395729856VKORC1c.339T>A (p.Ser113=)
c.400T>A (p.Ser134Thr)
c.421T>A (p.Ser141Thr)
c.229T>A (p.Ser77Thr)
c.433T>A (p.Ser145Thr)
c.301T>A
c.24T>A (p.Ser8=)
c.436T>A (p.Ser146Thr)
c.283+2025T>A (n.283+2025T>A)
c.173+3270T>A (n.173+3270T>A)
c.212T>A
c.423T>A (p.Ser141=)
n.1127T>A
16g.31091288G>ACA395729859VKORC1c.338C>T (p.Ser113Phe)
c.399C>T (p.Val133=)
c.420C>T (p.Val140=)
c.228C>T (p.Val76=)
c.432C>T (p.Val144=)
c.300C>T
c.23C>T (p.Ser8Phe)
c.435C>T (p.Val145=)
c.283+2024C>T (n.283+2024C>T)
c.173+3269C>T (n.173+3269C>T)
c.211C>T
c.422C>T (p.Ser141Phe)
n.1126C>T
16g.31091288G>CCA395729860VKORC1c.338C>G (p.Ser113Cys)
c.399C>G (p.Val133=)
c.420C>G (p.Val140=)
c.228C>G (p.Val76=)
c.432C>G (p.Val144=)
c.300C>G
c.23C>G (p.Ser8Cys)
c.435C>G (p.Val145=)
c.283+2024C>G (n.283+2024C>G)
c.173+3269C>G (n.173+3269C>G)
c.211C>G
c.422C>G (p.Ser141Cys)
n.1126C>G
16g.31091288G>TCA395729862VKORC1c.338C>A (p.Ser113Tyr)
c.399C>A (p.Val133=)
c.420C>A (p.Val140=)
c.228C>A (p.Val76=)
c.432C>A (p.Val144=)
c.300C>A
c.23C>A (p.Ser8Tyr)
c.435C>A (p.Val145=)
c.283+2024C>A (n.283+2024C>A)
c.173+3269C>A (n.173+3269C>A)
c.211C>A
c.422C>A (p.Ser141Tyr)
n.1126C>A
16g.31091289A=CA2216889217VKORC1c.337T= (p.Ser113=)
c.398T= (p.Val133=)
c.419T= (p.Val140=)
c.227T= (p.Val76=)
c.431T= (p.Val144=)
c.299T=
c.22T= (p.Ser8=)
c.434T= (p.Val145=)
c.283+2023T= (n.283+2023T=)
c.173+3268T= (n.173+3268T=)
c.210T=
c.421T= (p.Ser141=)
n.1125T=
16g.31091289A>CCA395729864VKORC1c.337T>G (p.Ser113Ala)
c.398T>G (p.Val133Gly)
c.419T>G (p.Val140Gly)
c.227T>G (p.Val76Gly)
c.431T>G (p.Val144Gly)
c.299T>G
c.22T>G (p.Ser8Ala)
c.434T>G (p.Val145Gly)
c.283+2023T>G (n.283+2023T>G)
c.173+3268T>G (n.173+3268T>G)
c.210T>G
c.421T>G (p.Ser141Ala)
n.1125T>G
 dbSNP gnomAD v2 gnomAD v4
16g.31091289A>GCA395729866VKORC1c.337T>C (p.Ser113Pro)
c.398T>C (p.Val133Ala)
c.419T>C (p.Val140Ala)
c.227T>C (p.Val76Ala)
c.431T>C (p.Val144Ala)
c.299T>C
c.22T>C (p.Ser8Pro)
c.434T>C (p.Val145Ala)
c.283+2023T>C (n.283+2023T>C)
c.173+3268T>C (n.173+3268T>C)
c.210T>C
c.421T>C (p.Ser141Pro)
n.1125T>C
16g.31091289A>TCA395729867VKORC1c.337T>A (p.Ser113Thr)
c.398T>A (p.Val133Asp)
c.419T>A (p.Val140Asp)
c.227T>A (p.Val76Asp)
c.431T>A (p.Val144Asp)
c.299T>A
c.22T>A (p.Ser8Thr)
c.434T>A (p.Val145Asp)
c.283+2023T>A (n.283+2023T>A)
c.173+3268T>A (n.173+3268T>A)
c.210T>A
c.421T>A (p.Ser141Thr)
n.1125T>A
16g.31091290C>ACA395729870VKORC1c.336G>T (p.Val112=)
c.397G>T (p.Val133Phe)
c.418G>T (p.Val140Phe)
c.226G>T (p.Val76Phe)
c.430G>T (p.Val144Phe)
c.298G>T
c.21G>T (p.Val7=)
c.433G>T (p.Val145Phe)
c.283+2022G>T (n.283+2022G>T)
c.173+3267G>T (n.173+3267G>T)
c.209G>T
c.420G>T (p.Val140=)
n.1124G>T
16g.31091290C=CA2216889222VKORC1c.336G= (p.Val112=)
c.397G= (p.Val133=)
c.418G= (p.Val140=)
c.226G= (p.Val76=)
c.430G= (p.Val144=)
c.298G=
c.21G= (p.Val7=)
c.433G= (p.Val145=)
c.283+2022G= (n.283+2022G=)
c.173+3267G= (n.173+3267G=)
c.209G=
c.420G= (p.Val140=)
n.1124G=
16g.31091290C>GCA395729872VKORC1c.336G>C (p.Val112=)
c.397G>C (p.Val133Leu)
c.418G>C (p.Val140Leu)
c.226G>C (p.Val76Leu)
c.430G>C (p.Val144Leu)
c.298G>C
c.21G>C (p.Val7=)
c.433G>C (p.Val145Leu)
c.283+2022G>C (n.283+2022G>C)
c.173+3267G>C (n.173+3267G>C)
c.209G>C
c.420G>C (p.Val140=)
n.1124G>C
16g.31091290C>TCA395729873VKORC1c.336G>A (p.Val112=)
c.397G>A (p.Val133Ile)
c.418G>A (p.Val140Ile)
c.226G>A (p.Val76Ile)
c.430G>A (p.Val144Ile)
c.298G>A
c.21G>A (p.Val7=)
c.433G>A (p.Val145Ile)
c.283+2022G>A (n.283+2022G>A)
c.173+3267G>A (n.173+3267G>A)
c.209G>A
c.420G>A (p.Val140=)
n.1124G>A
 dbSNP gnomAD v2 gnomAD v4
16g.31091291A=CA2216889227VKORC1c.335T= (p.Val112=)
c.396T= (p.Gly132=)
c.417T= (p.Gly139=)
c.225T= (p.Gly75=)
c.429T= (p.Gly143=)
c.297T=
c.20T= (p.Val7=)
c.432T= (p.Gly144=)
c.283+2021T= (n.283+2021T=)
c.173+3266T= (n.173+3266T=)
c.208T=
c.419T= (p.Val140=)
n.1123T=
16g.31091291A>CCA395729876VKORC1c.335T>G (p.Val112Gly)
c.396T>G (p.Gly132=)
c.417T>G (p.Gly139=)
c.225T>G (p.Gly75=)
c.429T>G (p.Gly143=)
c.297T>G
c.20T>G (p.Val7Gly)
c.432T>G (p.Gly144=)
c.283+2021T>G (n.283+2021T>G)
c.173+3266T>G (n.173+3266T>G)
c.208T>G
c.419T>G (p.Val140Gly)
n.1123T>G
 dbSNP
16g.31091291A>GCA395729879VKORC1c.335T>C (p.Val112Ala)
c.396T>C (p.Gly132=)
c.417T>C (p.Gly139=)
c.225T>C (p.Gly75=)
c.429T>C (p.Gly143=)
c.297T>C
c.20T>C (p.Val7Ala)
c.432T>C (p.Gly144=)
c.283+2021T>C (n.283+2021T>C)
c.173+3266T>C (n.173+3266T>C)
c.208T>C
c.419T>C (p.Val140Ala)
n.1123T>C
16g.31091291A>TCA395729878VKORC1c.335T>A (p.Val112Glu)
c.396T>A (p.Gly132=)
c.417T>A (p.Gly139=)
c.225T>A (p.Gly75=)
c.429T>A (p.Gly143=)
c.297T>A
c.20T>A (p.Val7Glu)
c.432T>A (p.Gly144=)
c.283+2021T>A (n.283+2021T>A)
c.173+3266T>A (n.173+3266T>A)
c.208T>A
c.419T>A (p.Val140Glu)
n.1123T>A
16g.31091292C>ACA395729881VKORC1c.334G>T (p.Val112Leu)
c.395G>T (p.Gly132Val)
c.416G>T (p.Gly139Val)
c.224G>T (p.Gly75Val)
c.428G>T (p.Gly143Val)
c.296G>T
c.19G>T (p.Val7Leu)
c.431G>T (p.Gly144Val)
c.283+2020G>T (n.283+2020G>T)
c.173+3265G>T (n.173+3265G>T)
c.207G>T
c.418G>T (p.Val140Leu)
n.1122G>T
 gnomAD v4
16g.31091292C=CA2216889233VKORC1c.334G= (p.Val112=)
c.395G= (p.Gly132=)
c.416G= (p.Gly139=)
c.224G= (p.Gly75=)
c.428G= (p.Gly143=)
c.296G=
c.19G= (p.Val7=)
c.431G= (p.Gly144=)
c.283+2020G= (n.283+2020G=)
c.173+3265G= (n.173+3265G=)
c.207G=
c.418G= (p.Val140=)
n.1122G=
16g.31091292C>GCA395729882VKORC1c.334G>C (p.Val112Leu)
c.395G>C (p.Gly132Ala)
c.416G>C (p.Gly139Ala)
c.224G>C (p.Gly75Ala)
c.428G>C (p.Gly143Ala)
c.296G>C
c.19G>C (p.Val7Leu)
c.431G>C (p.Gly144Ala)
c.283+2020G>C (n.283+2020G>C)
c.173+3265G>C (n.173+3265G>C)
c.207G>C
c.418G>C (p.Val140Leu)
n.1122G>C
16g.31091292C>TCA280619974VKORC1c.334G>A (p.Val112Met)
c.395G>A (p.Gly132Asp)
c.416G>A (p.Gly139Asp)
c.224G>A (p.Gly75Asp)
c.428G>A (p.Gly143Asp)
c.296G>A
c.19G>A (p.Val7Met)
c.431G>A (p.Gly144Asp)
c.283+2020G>A (n.283+2020G>A)
c.173+3265G>A (n.173+3265G>A)
c.207G>A
c.418G>A (p.Val140Met)
n.1122G>A
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
16g.31091293C>ACA395729885VKORC1c.333G>T (p.Leu111=)
c.394G>T (p.Gly132Cys)
c.415G>T (p.Gly139Cys)
c.223G>T (p.Gly75Cys)
c.427G>T (p.Gly143Cys)
c.295G>T
c.18G>T (p.Leu6=)
c.430G>T (p.Gly144Cys)
c.283+2019G>T (n.283+2019G>T)
c.173+3264G>T (n.173+3264G>T)
c.206G>T
c.417G>T (p.Leu139=)
n.1121G>T
16g.31091293C=CA2216889237VKORC1c.333G= (p.Leu111=)
c.394G= (p.Gly132=)
c.415G= (p.Gly139=)
c.223G= (p.Gly75=)
c.427G= (p.Gly143=)
c.295G=
c.18G= (p.Leu6=)
c.430G= (p.Gly144=)
c.283+2019G= (n.283+2019G=)
c.173+3264G= (n.173+3264G=)
c.206G=
c.417G= (p.Leu139=)
n.1121G=
16g.31091293C>GCA395729887VKORC1c.333G>C (p.Leu111=)
c.394G>C (p.Gly132Arg)
c.415G>C (p.Gly139Arg)
c.223G>C (p.Gly75Arg)
c.427G>C (p.Gly143Arg)
c.295G>C
c.18G>C (p.Leu6=)
c.430G>C (p.Gly144Arg)
c.283+2019G>C (n.283+2019G>C)
c.173+3264G>C (n.173+3264G>C)
c.206G>C
c.417G>C (p.Leu139=)
n.1121G>C
16g.31091293C>TCA395729888VKORC1c.333G>A (p.Leu111=)
c.394G>A (p.Gly132Ser)
c.415G>A (p.Gly139Ser)
c.223G>A (p.Gly75Ser)
c.427G>A (p.Gly143Ser)
c.295G>A
c.18G>A (p.Leu6=)
c.430G>A (p.Gly144Ser)
c.283+2019G>A (n.283+2019G>A)
c.173+3264G>A (n.173+3264G>A)
c.206G>A
c.417G>A (p.Leu139=)
n.1121G>A
 dbSNP gnomAD v4
16g.31091294A=CA2216889244VKORC1c.332T= (p.Leu111=)
c.393T= (p.Pro131=)
c.414T= (p.Pro138=)
c.222T= (p.Pro74=)
c.426T= (p.Pro142=)
c.294T=
c.17T= (p.Leu6=)
c.429T= (p.Pro143=)
c.283+2018T= (n.283+2018T=)
c.173+3263T= (n.173+3263T=)
c.205T=
c.416T= (p.Leu139=)
n.1120T=
16g.31091294A>CCA395729890VKORC1c.332T>G (p.Leu111Arg)
c.393T>G (p.Pro131=)
c.414T>G (p.Pro138=)
c.222T>G (p.Pro74=)
c.426T>G (p.Pro142=)
c.294T>G
c.17T>G (p.Leu6Arg)
c.429T>G (p.Pro143=)
c.283+2018T>G (n.283+2018T>G)
c.173+3263T>G (n.173+3263T>G)
c.205T>G
c.416T>G (p.Leu139Arg)
n.1120T>G
 dbSNP gnomAD v3 gnomAD v4
16g.31091294A>GCA280619979VKORC1c.332T>C (p.Leu111Pro)
c.393T>C (p.Pro131=)
c.414T>C (p.Pro138=)
c.222T>C (p.Pro74=)
c.426T>C (p.Pro142=)
c.294T>C
c.17T>C (p.Leu6Pro)
c.429T>C (p.Pro143=)
c.283+2018T>C (n.283+2018T>C)
c.173+3263T>C (n.173+3263T>C)
c.205T>C
c.416T>C (p.Leu139Pro)
n.1120T>C
 dbSNP
16g.31091294A>TCA395729893VKORC1c.332T>A (p.Leu111Gln)
c.393T>A (p.Pro131=)
c.414T>A (p.Pro138=)
c.222T>A (p.Pro74=)
c.426T>A (p.Pro142=)
c.294T>A
c.17T>A (p.Leu6Gln)
c.429T>A (p.Pro143=)
c.283+2018T>A (n.283+2018T>A)
c.173+3263T>A (n.173+3263T>A)
c.205T>A
c.416T>A (p.Leu139Gln)
n.1120T>A
16g.31091295G>ACA395729895VKORC1c.331C>T (p.Leu111=)
c.392C>T (p.Pro131Leu)
c.413C>T (p.Pro138Leu)
c.221C>T (p.Pro74Leu)
c.425C>T (p.Pro142Leu)
c.293C>T
c.16C>T (p.Leu6=)
c.428C>T (p.Pro143Leu)
c.283+2017C>T (n.283+2017C>T)
c.173+3262C>T (n.173+3262C>T)
c.204C>T
c.415C>T (p.Leu139=)
n.1119C>T
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
16g.31091295G>CCA395729897VKORC1c.331C>G (p.Leu111Val)
c.392C>G (p.Pro131Arg)
c.413C>G (p.Pro138Arg)
c.221C>G (p.Pro74Arg)
c.425C>G (p.Pro142Arg)
c.293C>G
c.16C>G (p.Leu6Val)
c.428C>G (p.Pro143Arg)
c.283+2017C>G (n.283+2017C>G)
c.173+3262C>G (n.173+3262C>G)
c.204C>G
c.415C>G (p.Leu139Val)
n.1119C>G
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
16g.31091295G=CA2216889249VKORC1c.331C= (p.Leu111=)
c.392C= (p.Pro131=)
c.413C= (p.Pro138=)
c.221C= (p.Pro74=)
c.425C= (p.Pro142=)
c.293C=
c.16C= (p.Leu6=)
c.428C= (p.Pro143=)
c.283+2017C= (n.283+2017C=)
c.173+3262C= (n.173+3262C=)
c.204C=
c.415C= (p.Leu139=)
n.1119C=
16g.31091295G>TCA395729898VKORC1c.331C>A (p.Leu111Met)
c.392C>A (p.Pro131His)
c.413C>A (p.Pro138His)
c.221C>A (p.Pro74His)
c.425C>A (p.Pro142His)
c.293C>A
c.16C>A (p.Leu6Met)
c.428C>A (p.Pro143His)
c.283+2017C>A (n.283+2017C>A)
c.173+3262C>A (n.173+3262C>A)
c.204C>A
c.415C>A (p.Leu139Met)
n.1119C>A
16g.31091296G>ACA395729904VKORC1c.330C>T (p.Ser110=)
c.391C>T (p.Pro131Ser)
c.412C>T (p.Pro138Ser)
c.220C>T (p.Pro74Ser)
c.424C>T (p.Pro142Ser)
c.292C>T
c.15C>T (p.Ser5=)
c.427C>T (p.Pro143Ser)
c.283+2016C>T (n.283+2016C>T)
c.173+3261C>T (n.173+3261C>T)
c.203C>T
c.414C>T (p.Ser138=)
n.1118C>T
 gnomAD v4
16g.31091296G>CCA395729900VKORC1c.330C>G (p.Ser110=)
c.391C>G (p.Pro131Ala)
c.412C>G (p.Pro138Ala)
c.220C>G (p.Pro74Ala)
c.424C>G (p.Pro142Ala)
c.292C>G
c.15C>G (p.Ser5=)
c.427C>G (p.Pro143Ala)
c.283+2016C>G (n.283+2016C>G)
c.173+3261C>G (n.173+3261C>G)
c.203C>G
c.414C>G (p.Ser138=)
n.1118C>G
16g.31091296G>TCA395729902VKORC1c.330C>A (p.Ser110=)
c.391C>A (p.Pro131Thr)
c.412C>A (p.Pro138Thr)
c.220C>A (p.Pro74Thr)
c.424C>A (p.Pro142Thr)
c.292C>A
c.15C>A (p.Ser5=)
c.427C>A (p.Pro143Thr)
c.283+2016C>A (n.283+2016C>A)
c.173+3261C>A (n.173+3261C>A)
c.203C>A
c.414C>A (p.Ser138=)
n.1118C>A
16g.31091297G>ACA280619980VKORC1c.329C>T (p.Ser110Phe)
c.390C>T (p.Leu130=)
c.411C>T (p.Leu137=)
c.219C>T (p.Leu73=)
c.423C>T (p.Leu141=)
c.291C>T
c.14C>T (p.Ser5Phe)
c.426C>T (p.Leu142=)
c.283+2015C>T (n.283+2015C>T)
c.173+3260C>T (n.173+3260C>T)
c.202C>T
c.413C>T (p.Ser138Phe)
n.1117C>T
 dbSNP gnomAD v3 gnomAD v4
16g.31091297G>CCA395729906VKORC1c.329C>G (p.Ser110Cys)
c.390C>G (p.Leu130=)
c.411C>G (p.Leu137=)
c.219C>G (p.Leu73=)
c.423C>G (p.Leu141=)
c.291C>G
c.14C>G (p.Ser5Cys)
c.426C>G (p.Leu142=)
c.283+2015C>G (n.283+2015C>G)
c.173+3260C>G (n.173+3260C>G)
c.202C>G
c.413C>G (p.Ser138Cys)
n.1117C>G
16g.31091297G=CA2216889254VKORC1c.329C= (p.Ser110=)
c.390C= (p.Leu130=)
c.411C= (p.Leu137=)
c.219C= (p.Leu73=)
c.423C= (p.Leu141=)
c.291C=
c.14C= (p.Ser5=)
c.426C= (p.Leu142=)
c.283+2015C= (n.283+2015C=)
c.173+3260C= (n.173+3260C=)
c.202C=
c.413C= (p.Ser138=)
n.1117C=
16g.31091297G>TCA395729908VKORC1c.329C>A (p.Ser110Tyr)
c.390C>A (p.Leu130=)
c.411C>A (p.Leu137=)
c.219C>A (p.Leu73=)
c.423C>A (p.Leu141=)
c.291C>A
c.14C>A (p.Ser5Tyr)
c.426C>A (p.Leu142=)
c.283+2015C>A (n.283+2015C>A)
c.173+3260C>A (n.173+3260C>A)
c.202C>A
c.413C>A (p.Ser138Tyr)
n.1117C>A
 gnomAD v4
16g.31091298A=CA2216889260VKORC1c.328T= (p.Ser110=)
c.389T= (p.Leu130=)
c.410T= (p.Leu137=)
c.218T= (p.Leu73=)
c.422T= (p.Leu141=)
c.290T=
c.13T= (p.Ser5=)
c.425T= (p.Leu142=)
c.283+2014T= (n.283+2014T=)
c.173+3259T= (n.173+3259T=)
c.201T=
c.412T= (p.Ser138=)
n.1116T=
16g.31091298A>CCA395729910VKORC1c.328T>G (p.Ser110Ala)
c.389T>G (p.Leu130Arg)
c.410T>G (p.Leu137Arg)
c.218T>G (p.Leu73Arg)
c.422T>G (p.Leu141Arg)
c.290T>G
c.13T>G (p.Ser5Ala)
c.425T>G (p.Leu142Arg)
c.283+2014T>G (n.283+2014T>G)
c.173+3259T>G (n.173+3259T>G)
c.201T>G
c.412T>G (p.Ser138Ala)
n.1116T>G
16g.31091298A>GCA395729912VKORC1c.328T>C (p.Ser110Pro)
c.389T>C (p.Leu130Pro)
c.410T>C (p.Leu137Pro)
c.218T>C (p.Leu73Pro)
c.422T>C (p.Leu141Pro)
c.290T>C
c.13T>C (p.Ser5Pro)
c.425T>C (p.Leu142Pro)
c.283+2014T>C (n.283+2014T>C)
c.173+3259T>C (n.173+3259T>C)
c.201T>C
c.412T>C (p.Ser138Pro)
n.1116T>C
16g.31091298A>TCA280619983VKORC1c.328T>A (p.Ser110Thr)
c.389T>A (p.Leu130His)
c.410T>A (p.Leu137His)
c.218T>A (p.Leu73His)
c.422T>A (p.Leu141His)
c.290T>A
c.13T>A (p.Ser5Thr)
c.425T>A (p.Leu142His)
c.283+2014T>A (n.283+2014T>A)
c.173+3259T>A (n.173+3259T>A)
c.201T>A
c.412T>A (p.Ser138Thr)
n.1116T>A
 dbSNP gnomAD v3 gnomAD v4
16g.31091299G>ACA395729915VKORC1c.327C>T (p.Ser109=)
c.388C>T (p.Leu130Phe)
c.409C>T (p.Leu137Phe)
c.217C>T (p.Leu73Phe)
c.421C>T (p.Leu141Phe)
c.289C>T
c.12C>T (p.Ser4=)
c.424C>T (p.Leu142Phe)
c.283+2013C>T (n.283+2013C>T)
c.173+3258C>T (n.173+3258C>T)
c.200C>T
c.411C>T (p.Ser137=)
n.1115C>T
16g.31091299G>CCA395729916VKORC1c.327C>G (p.Ser109Arg)
c.388C>G (p.Leu130Val)
c.409C>G (p.Leu137Val)
c.217C>G (p.Leu73Val)
c.421C>G (p.Leu141Val)
c.289C>G
c.12C>G (p.Ser4Arg)
c.424C>G (p.Leu142Val)
c.283+2013C>G (n.283+2013C>G)
c.173+3258C>G (n.173+3258C>G)
c.200C>G
c.411C>G (p.Ser137Arg)
n.1115C>G
 dbSNP
16g.31091299G=CA2216889264VKORC1c.327C= (p.Ser109=)
c.388C= (p.Leu130=)
c.409C= (p.Leu137=)
c.217C= (p.Leu73=)
c.421C= (p.Leu141=)
c.289C=
c.12C= (p.Ser4=)
c.424C= (p.Leu142=)
c.283+2013C= (n.283+2013C=)
c.173+3258C= (n.173+3258C=)
c.200C=
c.411C= (p.Ser137=)
n.1115C=
16g.31091299G>TCA395729918VKORC1c.327C>A (p.Ser109Arg)
c.388C>A (p.Leu130Ile)
c.409C>A (p.Leu137Ile)
c.217C>A (p.Leu73Ile)
c.421C>A (p.Leu141Ile)
c.289C>A
c.12C>A (p.Ser4Arg)
c.424C>A (p.Leu142Ile)
c.283+2013C>A (n.283+2013C>A)
c.173+3258C>A (n.173+3258C>A)
c.200C>A
c.411C>A (p.Ser137Arg)
n.1115C>A
16g.31091300C>ACA395729920VKORC1c.326G>T (p.Ser109Ile)
c.387G>T (p.Glu129Asp)
c.408G>T (p.Glu136Asp)
c.216G>T (p.Glu72Asp)
c.420G>T (p.Glu140Asp)
c.288G>T
c.11G>T (p.Ser4Ile)
c.423G>T (p.Glu141Asp)
c.283+2012G>T (n.283+2012G>T)
c.173+3257G>T (n.173+3257G>T)
c.199G>T
c.410G>T (p.Ser137Ile)
n.1114G>T
16g.31091300C=CA2216889269VKORC1c.326G= (p.Ser109=)
c.387G= (p.Glu129=)
c.408G= (p.Glu136=)
c.216G= (p.Glu72=)
c.420G= (p.Glu140=)
c.288G=
c.11G= (p.Ser4=)
c.423G= (p.Glu141=)
c.283+2012G= (n.283+2012G=)
c.173+3257G= (n.173+3257G=)
c.199G=
c.410G= (p.Ser137=)
n.1114G=
16g.31091300C>GCA395729922VKORC1c.326G>C (p.Ser109Thr)
c.387G>C (p.Glu129Asp)
c.408G>C (p.Glu136Asp)
c.216G>C (p.Glu72Asp)
c.420G>C (p.Glu140Asp)
c.288G>C
c.11G>C (p.Ser4Thr)
c.423G>C (p.Glu141Asp)
c.283+2012G>C (n.283+2012G>C)
c.173+3257G>C (n.173+3257G>C)
c.199G>C
c.410G>C (p.Ser137Thr)
n.1114G>C
16g.31091300C>TCA395729923VKORC1c.326G>A (p.Ser109Asn)
c.387G>A (p.Glu129=)
c.408G>A (p.Glu136=)
c.216G>A (p.Glu72=)
c.420G>A (p.Glu140=)
c.288G>A
c.11G>A (p.Ser4Asn)
c.423G>A (p.Glu141=)
c.283+2012G>A (n.283+2012G>A)
c.173+3257G>A (n.173+3257G>A)
c.199G>A
c.410G>A (p.Ser137Asn)
n.1114G>A
 dbSNP gnomAD v2 gnomAD v4
16g.31091301T>ACA395729926VKORC1c.325A>T (p.Ser109Cys)
c.386A>T (p.Glu129Val)
c.407A>T (p.Glu136Val)
c.215A>T (p.Glu72Val)
c.419A>T (p.Glu140Val)
c.287A>T
c.10A>T (p.Ser4Cys)
c.422A>T (p.Glu141Val)
c.283+2011A>T (n.283+2011A>T)
c.173+3256A>T (n.173+3256A>T)
c.198A>T
c.409A>T (p.Ser137Cys)
n.1113A>T
16g.31091301T>CCA395729927VKORC1c.325A>G (p.Ser109Gly)
c.386A>G (p.Glu129Gly)
c.407A>G (p.Glu136Gly)
c.215A>G (p.Glu72Gly)
c.419A>G (p.Glu140Gly)
c.287A>G
c.10A>G (p.Ser4Gly)
c.422A>G (p.Glu141Gly)
c.283+2011A>G (n.283+2011A>G)
c.173+3256A>G (n.173+3256A>G)
c.198A>G
c.409A>G (p.Ser137Gly)
n.1113A>G
16g.31091301T>GCA395729925VKORC1c.325A>C (p.Ser109Arg)
c.386A>C (p.Glu129Ala)
c.407A>C (p.Glu136Ala)
c.215A>C (p.Glu72Ala)
c.419A>C (p.Glu140Ala)
c.287A>C
c.10A>C (p.Ser4Arg)
c.422A>C (p.Glu141Ala)
c.283+2011A>C (n.283+2011A>C)
c.173+3256A>C (n.173+3256A>C)
c.198A>C
c.409A>C (p.Ser137Arg)
n.1113A>C
16g.31091302C>ACA395729931VKORC1c.324G>T (p.Leu108=)
c.385G>T (p.Glu129Ter)
c.406G>T (p.Glu136Ter)
c.214G>T (p.Glu72Ter)
c.418G>T (p.Glu140Ter)
c.286G>T
c.9G>T (p.Leu3=)
c.421G>T (p.Glu141Ter)
c.283+2010G>T (n.283+2010G>T)
c.173+3255G>T (n.173+3255G>T)
c.197G>T
c.408G>T (p.Leu136=)
n.1112G>T
16g.31091302C=CA2216889273VKORC1c.324G= (p.Leu108=)
c.385G= (p.Glu129=)
c.406G= (p.Glu136=)
c.214G= (p.Glu72=)
c.418G= (p.Glu140=)
c.286G=
c.9G= (p.Leu3=)
c.421G= (p.Glu141=)
c.283+2010G= (n.283+2010G=)
c.173+3255G= (n.173+3255G=)
c.197G=
c.408G= (p.Leu136=)
n.1112G=
16g.31091302C>GCA395729930VKORC1c.324G>C (p.Leu108=)
c.385G>C (p.Glu129Gln)
c.406G>C (p.Glu136Gln)
c.214G>C (p.Glu72Gln)
c.418G>C (p.Glu140Gln)
c.286G>C
c.9G>C (p.Leu3=)
c.421G>C (p.Glu141Gln)
c.283+2010G>C (n.283+2010G>C)
c.173+3255G>C (n.173+3255G>C)
c.197G>C
c.408G>C (p.Leu136=)
n.1112G>C
16g.31091302C>TCA395729932VKORC1c.324G>A (p.Leu108=)
c.385G>A (p.Glu129Lys)
c.406G>A (p.Glu136Lys)
c.214G>A (p.Glu72Lys)
c.418G>A (p.Glu140Lys)
c.286G>A
c.9G>A (p.Leu3=)
c.421G>A (p.Glu141Lys)
c.283+2010G>A (n.283+2010G>A)
c.173+3255G>A (n.173+3255G>A)
c.197G>A
c.408G>A (p.Leu136=)
n.1112G>A
 dbSNP gnomAD v3 gnomAD v4
16g.31091303A>CCA395729934VKORC1c.323T>G (p.Leu108Arg)
c.384T>G (p.Ala128=)
c.405T>G (p.Ala135=)
c.213T>G (p.Ala71=)
c.417T>G (p.Ala139=)
c.285T>G
c.8T>G (p.Leu3Arg)
c.420T>G (p.Ala140=)
c.283+2009T>G (n.283+2009T>G)
c.173+3254T>G (n.173+3254T>G)
c.196T>G
c.407T>G (p.Leu136Arg)
n.1111T>G
 gnomAD v4
16g.31091303A>GCA395729935VKORC1c.323T>C (p.Leu108Pro)
c.384T>C (p.Ala128=)
c.405T>C (p.Ala135=)
c.213T>C (p.Ala71=)
c.417T>C (p.Ala139=)
c.285T>C
c.8T>C (p.Leu3Pro)
c.420T>C (p.Ala140=)
c.283+2009T>C (n.283+2009T>C)
c.173+3254T>C (n.173+3254T>C)
c.196T>C
c.407T>C (p.Leu136Pro)
n.1111T>C
16g.31091303A>TCA395729937VKORC1c.323T>A (p.Leu108Gln)
c.384T>A (p.Ala128=)
c.405T>A (p.Ala135=)
c.213T>A (p.Ala71=)
c.417T>A (p.Ala139=)
c.285T>A
c.8T>A (p.Leu3Gln)
c.420T>A (p.Ala140=)
c.283+2009T>A (n.283+2009T>A)
c.173+3254T>A (n.173+3254T>A)
c.196T>A
c.407T>A (p.Leu136Gln)
n.1111T>A
16g.31091304G>ACA395729938VKORC1c.322C>T (p.Leu108=)
c.383C>T (p.Ala128Val)
c.404C>T (p.Ala135Val)
c.212C>T (p.Ala71Val)
c.416C>T (p.Ala139Val)
c.284C>T
c.7C>T (p.Leu3=)
c.419C>T (p.Ala140Val)
c.283+2008C>T (n.283+2008C>T)
c.173+3253C>T (n.173+3253C>T)
c.195C>T
c.406C>T (p.Leu136=)
n.1110C>T
16g.31091304G>CCA395729939VKORC1c.322C>G (p.Leu108Val)
c.383C>G (p.Ala128Gly)
c.404C>G (p.Ala135Gly)
c.212C>G (p.Ala71Gly)
c.416C>G (p.Ala139Gly)
c.284C>G
c.7C>G (p.Leu3Val)
c.419C>G (p.Ala140Gly)
c.283+2008C>G (n.283+2008C>G)
c.173+3253C>G (n.173+3253C>G)
c.195C>G
c.406C>G (p.Leu136Val)
n.1110C>G
16g.31091304G>TCA395729941VKORC1c.322C>A (p.Leu108Met)
c.383C>A (p.Ala128Asp)
c.404C>A (p.Ala135Asp)
c.212C>A (p.Ala71Asp)
c.416C>A (p.Ala139Asp)
c.284C>A
c.7C>A (p.Leu3Met)
c.419C>A (p.Ala140Asp)
c.283+2008C>A (n.283+2008C>A)
c.173+3253C>A (n.173+3253C>A)
c.195C>A
c.406C>A (p.Leu136Met)
n.1110C>A
16g.31091305C>ACA395729946VKORC1c.321G>T (p.Leu107=)
c.382G>T (p.Ala128Ser)
c.403G>T (p.Ala135Ser)
c.211G>T (p.Ala71Ser)
c.415G>T (p.Ala139Ser)
c.283G>T
c.6G>T (p.Leu2=)
c.418G>T (p.Ala140Ser)
c.283+2007G>T (n.283+2007G>T)
c.173+3252G>T (n.173+3252G>T)
c.194G>T
c.405G>T (p.Leu135=)
n.1109G>T
16g.31091305C>GCA395729945VKORC1c.321G>C (p.Leu107=)
c.382G>C (p.Ala128Pro)
c.403G>C (p.Ala135Pro)
c.211G>C (p.Ala71Pro)
c.415G>C (p.Ala139Pro)
c.283G>C
c.6G>C (p.Leu2=)
c.418G>C (p.Ala140Pro)
c.283+2007G>C (n.283+2007G>C)
c.173+3252G>C (n.173+3252G>C)
c.194G>C
c.405G>C (p.Leu135=)
n.1109G>C
16g.31091305C>TCA395729943VKORC1c.321G>A (p.Leu107=)
c.382G>A (p.Ala128Thr)
c.403G>A (p.Ala135Thr)
c.211G>A (p.Ala71Thr)
c.415G>A (p.Ala139Thr)
c.283G>A
c.6G>A (p.Leu2=)
c.418G>A (p.Ala140Thr)
c.283+2007G>A (n.283+2007G>A)
c.173+3252G>A (n.173+3252G>A)
c.194G>A
c.405G>A (p.Leu135=)
n.1109G>A
 dbSNP gnomAD v3 gnomAD v4
16g.31091306A>CCA395729948VKORC1c.320T>G (p.Leu107Arg)
c.381T>G (p.Ala127=)
c.402T>G (p.Ala134=)
c.210T>G (p.Ala70=)
c.414T>G (p.Ala138=)
c.282T>G
c.5T>G (p.Leu2Arg)
c.417T>G (p.Ala139=)
c.283+2006T>G (n.283+2006T>G)
c.173+3251T>G (n.173+3251T>G)
c.193T>G
c.404T>G (p.Leu135Arg)
n.1108T>G
16g.31091306A>GCA395729950VKORC1c.320T>C (p.Leu107Pro)
c.381T>C (p.Ala127=)
c.402T>C (p.Ala134=)
c.210T>C (p.Ala70=)
c.414T>C (p.Ala138=)
c.282T>C
c.5T>C (p.Leu2Pro)
c.417T>C (p.Ala139=)
c.283+2006T>C (n.283+2006T>C)
c.173+3251T>C (n.173+3251T>C)
c.193T>C
c.404T>C (p.Leu135Pro)
n.1108T>C
16g.31091306A>TCA395729952VKORC1c.320T>A (p.Leu107Gln)
c.381T>A (p.Ala127=)
c.402T>A (p.Ala134=)
c.210T>A (p.Ala70=)
c.414T>A (p.Ala138=)
c.282T>A
c.5T>A (p.Leu2Gln)
c.417T>A (p.Ala139=)
c.283+2006T>A (n.283+2006T>A)
c.173+3251T>A (n.173+3251T>A)
c.193T>A
c.404T>A (p.Leu135Gln)
n.1108T>A
16g.31091307G>ACA395729954VKORC1c.319C>T (p.Leu107=)
c.380C>T (p.Ala127Val)
c.401C>T (p.Ala134Val)
c.209C>T (p.Ala70Val)
c.413C>T (p.Ala138Val)
c.281C>T
c.4C>T (p.Leu2=)
c.416C>T (p.Ala139Val)
c.283+2005C>T (n.283+2005C>T)
c.173+3250C>T (n.173+3250C>T)
c.192C>T
c.403C>T (p.Leu135=)
n.1107C>T
16g.31091307G>CCA395729955VKORC1c.319C>G (p.Leu107Val)
c.380C>G (p.Ala127Gly)
c.401C>G (p.Ala134Gly)
c.209C>G (p.Ala70Gly)
c.413C>G (p.Ala138Gly)
c.281C>G
c.4C>G (p.Leu2Val)
c.416C>G (p.Ala139Gly)
c.283+2005C>G (n.283+2005C>G)
c.173+3250C>G (n.173+3250C>G)
c.192C>G
c.403C>G (p.Leu135Val)
n.1107C>G
16g.31091307G>TCA395729956VKORC1c.319C>A (p.Leu107Met)
c.380C>A (p.Ala127Asp)
c.401C>A (p.Ala134Asp)
c.209C>A (p.Ala70Asp)
c.413C>A (p.Ala138Asp)
c.281C>A
c.4C>A (p.Leu2Met)
c.416C>A (p.Ala139Asp)
c.283+2005C>A (n.283+2005C>A)
c.173+3250C>A (n.173+3250C>A)
c.192C>A
c.403C>A (p.Leu135Met)
n.1107C>A
16g.31091308C>ACA395729958VKORC1c.318G>T (p.Met106Ile)
c.379G>T (p.Ala127Ser)
c.400G>T (p.Ala134Ser)
c.208G>T (p.Ala70Ser)
c.412G>T (p.Ala138Ser)
c.280G>T
c.3G>T (p.Met1Ile)
c.415G>T (p.Ala139Ser)
c.283+2004G>T (n.283+2004G>T)
c.173+3249G>T (n.173+3249G>T)
c.191G>T
c.402G>T (p.Met134Ile)
n.1106G>T
16g.31091308C>GCA395729962VKORC1c.318G>C (p.Met106Ile)
c.379G>C (p.Ala127Pro)
c.400G>C (p.Ala134Pro)
c.208G>C (p.Ala70Pro)
c.412G>C (p.Ala138Pro)
c.280G>C
c.3G>C (p.Met1Ile)
c.415G>C (p.Ala139Pro)
c.283+2004G>C (n.283+2004G>C)
c.173+3249G>C (n.173+3249G>C)
c.191G>C
c.402G>C (p.Met134Ile)
n.1106G>C
16g.31091308C>TCA395729960VKORC1c.318G>A (p.Met106Ile)
c.379G>A (p.Ala127Thr)
c.400G>A (p.Ala134Thr)
c.208G>A (p.Ala70Thr)
c.412G>A (p.Ala138Thr)
c.280G>A
c.3G>A (p.Met1Ile)
c.415G>A (p.Ala139Thr)
c.283+2004G>A (n.283+2004G>A)
c.173+3249G>A (n.173+3249G>A)
c.191G>A
c.402G>A (p.Met134Ile)
n.1106G>A
16g.31091309A>CCA395729964VKORC1c.317T>G (p.Met106Arg)
c.378T>G (p.Asp126Glu)
c.399T>G (p.Asp133Glu)
c.207T>G (p.Asp69Glu)
c.411T>G (p.Asp137Glu)
c.279T>G
c.2T>G (p.Met1Arg)
c.414T>G (p.Asp138Glu)
c.283+2003T>G (n.283+2003T>G)
c.173+3248T>G (n.173+3248T>G)
c.190T>G
c.401T>G (p.Met134Arg)
n.1105T>G
16g.31091309A>GCA395729966VKORC1c.317T>C (p.Met106Thr)
c.378T>C (p.Asp126=)
c.399T>C (p.Asp133=)
c.207T>C (p.Asp69=)
c.411T>C (p.Asp137=)
c.279T>C
c.2T>C (p.Met1Thr)
c.414T>C (p.Asp138=)
c.283+2003T>C (n.283+2003T>C)
c.173+3248T>C (n.173+3248T>C)
c.190T>C
c.401T>C (p.Met134Thr)
n.1105T>C
 gnomAD v4
16g.31091309A>TCA395729967VKORC1c.317T>A (p.Met106Lys)
c.378T>A (p.Asp126Glu)
c.399T>A (p.Asp133Glu)
c.207T>A (p.Asp69Glu)
c.411T>A (p.Asp137Glu)
c.279T>A
c.2T>A (p.Met1Lys)
c.414T>A (p.Asp138Glu)
c.283+2003T>A (n.283+2003T>A)
c.173+3248T>A (n.173+3248T>A)
c.190T>A
c.401T>A (p.Met134Lys)
n.1105T>A
16g.31091310T>ACA395729969VKORC1c.316A>T (p.Met106Leu)
c.377A>T (p.Asp126Val)
c.398A>T (p.Asp133Val)
c.206A>T (p.Asp69Val)
c.410A>T (p.Asp137Val)
c.278A>T
c.1A>T (p.Met1Leu)
c.413A>T (p.Asp138Val)
c.283+2002A>T (n.283+2002A>T)
c.173+3247A>T (n.173+3247A>T)
c.189A>T
c.400A>T (p.Met134Leu)
n.1104A>T
 dbSNP
16g.31091310T>CCA395729970VKORC1c.316A>G (p.Met106Val)
c.377A>G (p.Asp126Gly)
c.398A>G (p.Asp133Gly)
c.206A>G (p.Asp69Gly)
c.410A>G (p.Asp137Gly)
c.278A>G
c.1A>G (p.Met1Val)
c.413A>G (p.Asp138Gly)
c.283+2002A>G (n.283+2002A>G)
c.173+3247A>G (n.173+3247A>G)
c.189A>G
c.400A>G (p.Met134Val)
n.1104A>G
16g.31091310T>GCA395729972VKORC1c.316A>C (p.Met106Leu)
c.377A>C (p.Asp126Ala)
c.398A>C (p.Asp133Ala)
c.206A>C (p.Asp69Ala)
c.410A>C (p.Asp137Ala)
c.278A>C
c.1A>C (p.Met1Leu)
c.413A>C (p.Asp138Ala)
c.283+2002A>C (n.283+2002A>C)
c.173+3247A>C (n.173+3247A>C)
c.189A>C
c.400A>C (p.Met134Leu)
n.1104A>C
16g.31091310T=CA2216889276VKORC1c.316A= (p.Met106=)
c.377A= (p.Asp126=)
c.398A= (p.Asp133=)
c.206A= (p.Asp69=)
c.410A= (p.Asp137=)
c.278A=
c.1A= (p.Met1=)
c.413A= (p.Asp138=)
c.283+2002A= (n.283+2002A=)
c.173+3247A= (n.173+3247A=)
c.189A=
c.400A= (p.Met134=)
n.1104A=
16g.31091311C>ACA395729974VKORC1c.315G>T (p.Leu105=)
c.376G>T (p.Asp126Tyr)
c.397G>T (p.Asp133Tyr)
c.205G>T (p.Asp69Tyr)
c.409G>T (p.Asp137Tyr)
c.277G>T
c.-1G>T (n.-1G>T)
c.412G>T (p.Asp138Tyr)
c.283+2001G>T (n.283+2001G>T)
c.173+3246G>T (n.173+3246G>T)
c.188G>T
c.399G>T (p.Leu133=)
n.1103G>T
16g.31091311C>GCA395729976VKORC1c.315G>C (p.Leu105=)
c.376G>C (p.Asp126His)
c.397G>C (p.Asp133His)
c.205G>C (p.Asp69His)
c.409G>C (p.Asp137His)
c.277G>C
c.-1G>C (n.-1G>C)
c.412G>C (p.Asp138His)
c.283+2001G>C (n.283+2001G>C)
c.173+3246G>C (n.173+3246G>C)
c.188G>C
c.399G>C (p.Leu133=)
n.1103G>C
16g.31091311C>TCA395729977VKORC1c.315G>A (p.Leu105=)
c.376G>A (p.Asp126Asn)
c.397G>A (p.Asp133Asn)
c.205G>A (p.Asp69Asn)
c.409G>A (p.Asp137Asn)
c.277G>A
c.-1G>A (n.-1G>A)
c.412G>A (p.Asp138Asn)
c.283+2001G>A (n.283+2001G>A)
c.173+3246G>A (n.173+3246G>A)
c.188G>A
c.399G>A (p.Leu133=)
n.1103G>A
16g.31091312A=CA2216889279VKORC1c.314T= (p.Leu105=)
c.375T= (p.Pro125=)
c.396T= (p.Pro132=)
c.204T= (p.Pro68=)
c.408T= (p.Pro136=)
c.276T=
c.-2T= (n.-2T=)
c.411T= (p.Pro137=)
c.283+2000T= (n.283+2000T=)
c.173+3245T= (n.173+3245T=)
c.187T=
c.398T= (p.Leu133=)
n.1102T=
16g.31091312A>CCA395729979VKORC1c.314T>G (p.Leu105Arg)
c.375T>G (p.Pro125=)
c.396T>G (p.Pro132=)
c.204T>G (p.Pro68=)
c.408T>G (p.Pro136=)
c.276T>G
c.-2T>G (n.-2T>G)
c.411T>G (p.Pro137=)
c.283+2000T>G (n.283+2000T>G)
c.173+3245T>G (n.173+3245T>G)
c.187T>G
c.398T>G (p.Leu133Arg)
n.1102T>G
16g.31091312A>GCA395729981VKORC1c.314T>C (p.Leu105Pro)
c.375T>C (p.Pro125=)
c.396T>C (p.Pro132=)
c.204T>C (p.Pro68=)
c.408T>C (p.Pro136=)
c.276T>C
c.-2T>C (n.-2T>C)
c.411T>C (p.Pro137=)
c.283+2000T>C (n.283+2000T>C)
c.173+3245T>C (n.173+3245T>C)
c.187T>C
c.398T>C (p.Leu133Pro)
n.1102T>C
 dbSNP gnomAD v3 gnomAD v4
16g.31091312A>TCA395729983VKORC1c.314T>A (p.Leu105Gln)
c.375T>A (p.Pro125=)
c.396T>A (p.Pro132=)
c.204T>A (p.Pro68=)
c.408T>A (p.Pro136=)
c.276T>A
c.-2T>A (n.-2T>A)
c.411T>A (p.Pro137=)
c.283+2000T>A (n.283+2000T>A)
c.173+3245T>A (n.173+3245T>A)
c.187T>A
c.398T>A (p.Leu133Gln)
n.1102T>A
16g.31091313G>ACA395729985VKORC1c.313C>T (p.Leu105=)
c.374C>T (p.Pro125Leu)
c.395C>T (p.Pro132Leu)
c.203C>T (p.Pro68Leu)
c.407C>T (p.Pro136Leu)
c.275C>T
c.-3C>T (n.-3C>T)
c.410C>T (p.Pro137Leu)
c.283+1999C>T (n.283+1999C>T)
c.173+3244C>T (n.173+3244C>T)
c.186C>T
c.397C>T (p.Leu133=)
n.1101C>T
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
16g.31091313G>CCA395729988VKORC1c.313C>G (p.Leu105Val)
c.374C>G (p.Pro125Arg)
c.395C>G (p.Pro132Arg)
c.203C>G (p.Pro68Arg)
c.407C>G (p.Pro136Arg)
c.275C>G
c.-3C>G (n.-3C>G)
c.410C>G (p.Pro137Arg)
c.283+1999C>G (n.283+1999C>G)
c.173+3244C>G (n.173+3244C>G)
c.186C>G
c.397C>G (p.Leu133Val)
n.1101C>G
16g.31091313G=CA2216889283VKORC1c.313C= (p.Leu105=)
c.374C= (p.Pro125=)
c.395C= (p.Pro132=)
c.203C= (p.Pro68=)
c.407C= (p.Pro136=)
c.275C=
c.-3C= (n.-3C=)
c.410C= (p.Pro137=)
c.283+1999C= (n.283+1999C=)
c.173+3244C= (n.173+3244C=)
c.186C=
c.397C= (p.Leu133=)
n.1101C=
16g.31091313G>TCA395729987VKORC1c.313C>A (p.Leu105Met)
c.374C>A (p.Pro125His)
c.395C>A (p.Pro132His)
c.203C>A (p.Pro68His)
c.407C>A (p.Pro136His)
c.275C>A
c.-3C>A (n.-3C>A)
c.410C>A (p.Pro137His)
c.283+1999C>A (n.283+1999C>A)
c.173+3244C>A (n.173+3244C>A)
c.186C>A
c.397C>A (p.Leu133Met)
n.1101C>A
 dbSNP
16g.31091314G>ACA395729989VKORC1c.312C>T (p.Val104=)
c.373C>T (p.Pro125Ser)
c.394C>T (p.Pro132Ser)
c.202C>T (p.Pro68Ser)
c.406C>T (p.Pro136Ser)
c.274C>T
c.-4C>T (n.-4C>T)
c.409C>T (p.Pro137Ser)
c.283+1998C>T (n.283+1998C>T)
c.173+3243C>T (n.173+3243C>T)
c.185C>T
c.396C>T (p.Val132=)
n.1100C>T
 dbSNP
16g.31091314G>CCA395729991VKORC1c.312C>G (p.Val104=)
c.373C>G (p.Pro125Ala)
c.394C>G (p.Pro132Ala)
c.202C>G (p.Pro68Ala)
c.406C>G (p.Pro136Ala)
c.274C>G
c.-4C>G (n.-4C>G)
c.409C>G (p.Pro137Ala)
c.283+1998C>G (n.283+1998C>G)
c.173+3243C>G (n.173+3243C>G)
c.185C>G
c.396C>G (p.Val132=)
n.1100C>G
 dbSNP gnomAD v3 gnomAD v4
16g.31091314G=CA2216889286VKORC1c.312C= (p.Val104=)
c.373C= (p.Pro125=)
c.394C= (p.Pro132=)
c.202C= (p.Pro68=)
c.406C= (p.Pro136=)
c.274C=
c.-4C= (n.-4C=)
c.409C= (p.Pro137=)
c.283+1998C= (n.283+1998C=)
c.173+3243C= (n.173+3243C=)
c.185C=
c.396C= (p.Val132=)
n.1100C=
16g.31091314G>TCA395729993VKORC1c.312C>A (p.Val104=)
c.373C>A (p.Pro125Thr)
c.394C>A (p.Pro132Thr)
c.202C>A (p.Pro68Thr)
c.406C>A (p.Pro136Thr)
c.274C>A
c.-4C>A (n.-4C>A)
c.409C>A (p.Pro137Thr)
c.283+1998C>A (n.283+1998C>A)
c.173+3243C>A (n.173+3243C>A)
c.185C>A
c.396C>A (p.Val132=)
n.1100C>A
16g.31091315A=CA2216889289VKORC1c.311T= (p.Val104=)
c.372T= (p.Cys124=)
c.393T= (p.Cys131=)
c.201T= (p.Cys67=)
c.405T= (p.Cys135=)
c.273T=
c.-5T= (n.-5T=)
c.408T= (p.Cys136=)
c.283+1997T= (n.283+1997T=)
c.173+3242T= (n.173+3242T=)
c.184T=
c.395T= (p.Val132=)
n.1099T=
16g.31091315A>CCA395729995VKORC1c.311T>G (p.Val104Gly)
c.372T>G (p.Cys124Trp)
c.393T>G (p.Cys131Trp)
c.201T>G (p.Cys67Trp)
c.405T>G (p.Cys135Trp)
c.273T>G
c.-5T>G (n.-5T>G)
c.408T>G (p.Cys136Trp)
c.283+1997T>G (n.283+1997T>G)
c.173+3242T>G (n.173+3242T>G)
c.184T>G
c.395T>G (p.Val132Gly)
n.1099T>G
 dbSNP gnomAD v2 gnomAD v4
16g.31091315A>GCA395729996VKORC1c.311T>C (p.Val104Ala)
c.372T>C (p.Cys124=)
c.393T>C (p.Cys131=)
c.201T>C (p.Cys67=)
c.405T>C (p.Cys135=)
c.273T>C
c.-5T>C (n.-5T>C)
c.408T>C (p.Cys136=)
c.283+1997T>C (n.283+1997T>C)
c.173+3242T>C (n.173+3242T>C)
c.184T>C
c.395T>C (p.Val132Ala)
n.1099T>C
16g.31091315A>TCA395729997VKORC1c.311T>A (p.Val104Asp)
c.372T>A (p.Cys124Ter)
c.393T>A (p.Cys131Ter)
c.201T>A (p.Cys67Ter)
c.405T>A (p.Cys135Ter)
c.273T>A
c.-5T>A (n.-5T>A)
c.408T>A (p.Cys136Ter)
c.283+1997T>A (n.283+1997T>A)
c.173+3242T>A (n.173+3242T>A)
c.184T>A
c.395T>A (p.Val132Asp)
n.1099T>A
16g.31091316C>ACA395730000VKORC1c.310G>T (p.Val104Phe)
c.371G>T (p.Cys124Phe)
c.392G>T (p.Cys131Phe)
c.200G>T (p.Cys67Phe)
c.404G>T (p.Cys135Phe)
c.272G>T
c.-6G>T (n.-6G>T)
c.407G>T (p.Cys136Phe)
c.283+1996G>T (n.283+1996G>T)
c.173+3241G>T (n.173+3241G>T)
c.183G>T
c.394G>T (p.Val132Phe)
n.1098G>T
16g.31091316C>GCA395730001VKORC1c.310G>C (p.Val104Leu)
c.371G>C (p.Cys124Ser)
c.392G>C (p.Cys131Ser)
c.200G>C (p.Cys67Ser)
c.404G>C (p.Cys135Ser)
c.272G>C
c.-6G>C (n.-6G>C)
c.407G>C (p.Cys136Ser)
c.283+1996G>C (n.283+1996G>C)
c.173+3241G>C (n.173+3241G>C)
c.183G>C
c.394G>C (p.Val132Leu)
n.1098G>C
16g.31091316C>TCA395730003VKORC1c.310G>A (p.Val104Ile)
c.371G>A (p.Cys124Tyr)
c.392G>A (p.Cys131Tyr)
c.200G>A (p.Cys67Tyr)
c.404G>A (p.Cys135Tyr)
c.272G>A
c.-6G>A (n.-6G>A)
c.407G>A (p.Cys136Tyr)
c.283+1996G>A (n.283+1996G>A)
c.173+3241G>A (n.173+3241G>A)
c.183G>A
c.394G>A (p.Val132Ile)
n.1098G>A
16g.31091317A>CCA395730005VKORC1c.309T>G (p.Ser103=)
c.370T>G (p.Cys124Gly)
c.391T>G (p.Cys131Gly)
c.199T>G (p.Cys67Gly)
c.403T>G (p.Cys135Gly)
c.271T>G
c.-7T>G (n.-7T>G)
c.406T>G (p.Cys136Gly)
c.283+1995T>G (n.283+1995T>G)
c.173+3240T>G (n.173+3240T>G)
c.182T>G
c.393T>G (p.Ser131=)
n.1097T>G
16g.31091317A>GCA395730006VKORC1c.309T>C (p.Ser103=)
c.370T>C (p.Cys124Arg)
c.391T>C (p.Cys131Arg)
c.199T>C (p.Cys67Arg)
c.403T>C (p.Cys135Arg)
c.271T>C
c.-7T>C (n.-7T>C)
c.406T>C (p.Cys136Arg)
c.283+1995T>C (n.283+1995T>C)
c.173+3240T>C (n.173+3240T>C)
c.182T>C
c.393T>C (p.Ser131=)
n.1097T>C
16g.31091317A>TCA395730007VKORC1c.309T>A (p.Ser103=)
c.370T>A (p.Cys124Ser)
c.391T>A (p.Cys131Ser)
c.199T>A (p.Cys67Ser)
c.403T>A (p.Cys135Ser)
c.271T>A
c.-7T>A (n.-7T>A)
c.406T>A (p.Cys136Ser)
c.283+1995T>A (n.283+1995T>A)
c.173+3240T>A (n.173+3240T>A)
c.182T>A
c.393T>A (p.Ser131=)
n.1097T>A
16g.31091318G>ACA395730012VKORC1c.308C>T (p.Ser103Phe)
c.369C>T (p.Leu123=)
c.390C>T (p.Leu130=)
c.198C>T (p.Leu66=)
c.402C>T (p.Leu134=)
c.270C>T
c.-8C>T (n.-8C>T)
c.405C>T (p.Leu135=)
c.283+1994C>T (n.283+1994C>T)
c.173+3239C>T (n.173+3239C>T)
c.181C>T
c.392C>T (p.Ser131Phe)
n.1096C>T
16g.31091318G>CCA395730011VKORC1c.308C>G (p.Ser103Cys)
c.369C>G (p.Leu123=)
c.390C>G (p.Leu130=)
c.198C>G (p.Leu66=)
c.402C>G (p.Leu134=)
c.270C>G
c.-8C>G (n.-8C>G)
c.405C>G (p.Leu135=)
c.283+1994C>G (n.283+1994C>G)
c.173+3239C>G (n.173+3239C>G)
c.181C>G
c.392C>G (p.Ser131Cys)
n.1096C>G
16g.31091318G>TCA395730009VKORC1c.308C>A (p.Ser103Tyr)
c.369C>A (p.Leu123=)
c.390C>A (p.Leu130=)
c.198C>A (p.Leu66=)
c.402C>A (p.Leu134=)
c.270C>A
c.-8C>A (n.-8C>A)
c.405C>A (p.Leu135=)
c.283+1994C>A (n.283+1994C>A)
c.173+3239C>A (n.173+3239C>A)
c.181C>A
c.392C>A (p.Ser131Tyr)
n.1096C>A
 gnomAD v4
16g.31091319A>CCA395730014VKORC1c.307T>G (p.Ser103Ala)
c.368T>G (p.Leu123Arg)
c.389T>G (p.Leu130Arg)
c.197T>G (p.Leu66Arg)
c.401T>G (p.Leu134Arg)
c.269T>G
c.-9T>G (n.-9T>G)
c.404T>G (p.Leu135Arg)
c.283+1993T>G (n.283+1993T>G)
c.173+3238T>G (n.173+3238T>G)
c.180T>G
c.391T>G (p.Ser131Ala)
n.1095T>G
16g.31091319A>GCA395730016VKORC1c.307T>C (p.Ser103Pro)
c.368T>C (p.Leu123Pro)
c.389T>C (p.Leu130Pro)
c.197T>C (p.Leu66Pro)
c.401T>C (p.Leu134Pro)
c.269T>C
c.-9T>C (n.-9T>C)
c.404T>C (p.Leu135Pro)
c.283+1993T>C (n.283+1993T>C)
c.173+3238T>C (n.173+3238T>C)
c.180T>C
c.391T>C (p.Ser131Pro)
n.1095T>C
16g.31091319A>TCA395730017VKORC1c.307T>A (p.Ser103Thr)
c.368T>A (p.Leu123His)
c.389T>A (p.Leu130His)
c.197T>A (p.Leu66His)
c.401T>A (p.Leu134His)
c.269T>A
c.-9T>A (n.-9T>A)
c.404T>A (p.Leu135His)
c.283+1993T>A (n.283+1993T>A)
c.173+3238T>A (n.173+3238T>A)
c.180T>A
c.391T>A (p.Ser131Thr)
n.1095T>A
16g.31091320G>ACA395730018VKORC1c.306C>T (p.Ala102=)
c.367C>T (p.Leu123Phe)
c.388C>T (p.Leu130Phe)
c.196C>T (p.Leu66Phe)
c.400C>T (p.Leu134Phe)
c.268C>T
c.-10C>T (n.-10C>T)
c.403C>T (p.Leu135Phe)
c.283+1992C>T (n.283+1992C>T)
c.173+3237C>T (n.173+3237C>T)
c.179C>T
c.390C>T (p.Ala130=)
n.1094C>T
 dbSNP gnomAD v3 gnomAD v4
16g.31091320G>CCA395730019VKORC1c.306C>G (p.Ala102=)
c.367C>G (p.Leu123Val)
c.388C>G (p.Leu130Val)
c.196C>G (p.Leu66Val)
c.400C>G (p.Leu134Val)
c.268C>G
c.-10C>G (n.-10C>G)
c.403C>G (p.Leu135Val)
c.283+1992C>G (n.283+1992C>G)
c.173+3237C>G (n.173+3237C>G)
c.179C>G
c.390C>G (p.Ala130=)
n.1094C>G
16g.31091320G=CA2216889292VKORC1c.306C= (p.Ala102=)
c.367C= (p.Leu123=)
c.388C= (p.Leu130=)
c.196C= (p.Leu66=)
c.400C= (p.Leu134=)
c.268C=
c.-10C= (n.-10C=)
c.403C= (p.Leu135=)
c.283+1992C= (n.283+1992C=)
c.173+3237C= (n.173+3237C=)
c.179C=
c.390C= (p.Ala130=)
n.1094C=
16g.31091320G>TCA395730020VKORC1c.306C>A (p.Ala102=)
c.367C>A (p.Leu123Ile)
c.388C>A (p.Leu130Ile)
c.196C>A (p.Leu66Ile)
c.400C>A (p.Leu134Ile)
c.268C>A
c.-10C>A (n.-10C>A)
c.403C>A (p.Leu135Ile)
c.283+1992C>A (n.283+1992C>A)
c.173+3237C>A (n.173+3237C>A)
c.179C>A
c.390C>A (p.Ala130=)
n.1094C>A
16g.31091321G>ACA395730021VKORC1c.305C>T (p.Ala102Val)
c.366C>T (p.Gly122=)
c.387C>T (p.Gly129=)
c.195C>T (p.Gly65=)
c.399C>T (p.Gly133=)
c.267C>T
c.-11C>T (n.-11C>T)
c.402C>T (p.Gly134=)
c.283+1991C>T (n.283+1991C>T)
c.173+3236C>T (n.173+3236C>T)
c.178C>T
c.389C>T (p.Ala130Val)
n.1093C>T
16g.31091321G>CCA395730022VKORC1c.305C>G (p.Ala102Gly)
c.366C>G (p.Gly122=)
c.387C>G (p.Gly129=)
c.195C>G (p.Gly65=)
c.399C>G (p.Gly133=)
c.267C>G
c.-11C>G (n.-11C>G)
c.402C>G (p.Gly134=)
c.283+1991C>G (n.283+1991C>G)
c.173+3236C>G (n.173+3236C>G)
c.178C>G
c.389C>G (p.Ala130Gly)
n.1093C>G
16g.31091321G>TCA395730024VKORC1c.305C>A (p.Ala102Asp)
c.366C>A (p.Gly122=)
c.387C>A (p.Gly129=)
c.195C>A (p.Gly65=)
c.399C>A (p.Gly133=)
c.267C>A
c.-11C>A (n.-11C>A)
c.402C>A (p.Gly134=)
c.283+1991C>A (n.283+1991C>A)
c.173+3236C>A (n.173+3236C>A)
c.178C>A
c.389C>A (p.Ala130Asp)
n.1093C>A
16g.31091322C>ACA395730026VKORC1c.304G>T (p.Ala102Ser)
c.365G>T (p.Gly122Val)
c.386G>T (p.Gly129Val)
c.194G>T (p.Gly65Val)
c.398G>T (p.Gly133Val)
c.266G>T
c.-12G>T (n.-12G>T)
c.401G>T (p.Gly134Val)
c.283+1990G>T (n.283+1990G>T)
c.173+3235G>T (n.173+3235G>T)
c.177G>T
c.388G>T (p.Ala130Ser)
n.1092G>T
16g.31091322C>GCA395730028VKORC1c.304G>C (p.Ala102Pro)
c.365G>C (p.Gly122Ala)
c.386G>C (p.Gly129Ala)
c.194G>C (p.Gly65Ala)
c.398G>C (p.Gly133Ala)
c.266G>C
c.-12G>C (n.-12G>C)
c.401G>C (p.Gly134Ala)
c.283+1990G>C (n.283+1990G>C)
c.173+3235G>C (n.173+3235G>C)
c.177G>C
c.388G>C (p.Ala130Pro)
n.1092G>C
16g.31091322C>TCA395730029VKORC1c.304G>A (p.Ala102Thr)
c.365G>A (p.Gly122Asp)
c.386G>A (p.Gly129Asp)
c.194G>A (p.Gly65Asp)
c.398G>A (p.Gly133Asp)
c.266G>A
c.-12G>A (n.-12G>A)
c.401G>A (p.Gly134Asp)
c.283+1990G>A (n.283+1990G>A)
c.173+3235G>A (n.173+3235G>A)
c.177G>A
c.388G>A (p.Ala130Thr)
n.1092G>A
16g.31091324delCA2632821551VKORC1c.304del (p.Ala102ProfsTer4)
c.365del (p.Gly122AlafsTer?)
c.386del (p.Gly129AlafsTer?)
c.194del (p.Gly65AlafsTer?)
c.398del (p.Gly133AlafsTer?)
c.266del
c.-12del (n.-12del)
c.401del (p.Gly134AlafsTer?)
c.283+1990del (n.283+1990del)
c.173+3235del (n.173+3235del)
c.177del
c.388del (p.Ala130ProfsTer4)
n.1092del
 gnomAD v4
16g.31091323C>ACA395730032VKORC1c.303G>T (p.Trp101Cys)
c.364G>T (p.Gly122Cys)
c.385G>T (p.Gly129Cys)
c.193G>T (p.Gly65Cys)
c.397G>T (p.Gly133Cys)
c.265G>T
c.-13G>T (n.-13G>T)
c.400G>T (p.Gly134Cys)
c.283+1989G>T (n.283+1989G>T)
c.173+3234G>T (n.173+3234G>T)
c.176G>T
c.387G>T (p.Trp129Cys)
n.1091G>T
16g.31091323C=CA2216889298VKORC1c.303G= (p.Trp101=)
c.364G= (p.Gly122=)
c.385G= (p.Gly129=)
c.193G= (p.Gly65=)
c.397G= (p.Gly133=)
c.265G=
c.-13G= (n.-13G=)
c.400G= (p.Gly134=)
c.283+1989G= (n.283+1989G=)
c.173+3234G= (n.173+3234G=)
c.176G=
c.387G= (p.Trp129=)
n.1091G=
16g.31091323C>GCA395730031VKORC1c.303G>C (p.Trp101Cys)
c.364G>C (p.Gly122Arg)
c.385G>C (p.Gly129Arg)
c.193G>C (p.Gly65Arg)
c.397G>C (p.Gly133Arg)
c.265G>C
c.-13G>C (n.-13G>C)
c.400G>C (p.Gly134Arg)
c.283+1989G>C (n.283+1989G>C)
c.173+3234G>C (n.173+3234G>C)
c.176G>C
c.387G>C (p.Trp129Cys)
n.1091G>C
16g.31091323C>TCA395730030VKORC1c.303G>A (p.Trp101Ter)
c.364G>A (p.Gly122Ser)
c.385G>A (p.Gly129Ser)
c.193G>A (p.Gly65Ser)
c.397G>A (p.Gly133Ser)
c.265G>A
c.-13G>A (n.-13G>A)
c.400G>A (p.Gly134Ser)
c.283+1989G>A (n.283+1989G>A)
c.173+3234G>A (n.173+3234G>A)
c.176G>A
c.387G>A (p.Trp129Ter)
n.1091G>A
 dbSNP gnomAD v3 gnomAD v4
16g.31091324C>ACA395730034VKORC1c.302G>T (p.Trp101Leu)
c.363G>T (p.Leu121=)
c.384G>T (p.Leu128=)
c.192G>T (p.Leu64=)
c.396G>T (p.Leu132=)
c.264G>T
c.-14G>T (n.-14G>T)
c.399G>T (p.Leu133=)
c.283+1988G>T (n.283+1988G>T)
c.173+3233G>T (n.173+3233G>T)
c.175G>T
c.386G>T (p.Trp129Leu)
n.1090G>T
16g.31091324C>GCA395730037VKORC1c.302G>C (p.Trp101Ser)
c.363G>C (p.Leu121=)
c.384G>C (p.Leu128=)
c.192G>C (p.Leu64=)
c.396G>C (p.Leu132=)
c.264G>C
c.-14G>C (n.-14G>C)
c.399G>C (p.Leu133=)
c.283+1988G>C (n.283+1988G>C)
c.173+3233G>C (n.173+3233G>C)
c.175G>C
c.386G>C (p.Trp129Ser)
n.1090G>C
16g.31091324C>TCA395730035VKORC1c.302G>A (p.Trp101Ter)
c.363G>A (p.Leu121=)
c.384G>A (p.Leu128=)
c.192G>A (p.Leu64=)
c.396G>A (p.Leu132=)
c.264G>A
c.-14G>A (n.-14G>A)
c.399G>A (p.Leu133=)
c.283+1988G>A (n.283+1988G>A)
c.173+3233G>A (n.173+3233G>A)
c.175G>A
c.386G>A (p.Trp129Ter)
n.1090G>A
16g.31091325A>CCA395730039VKORC1c.301T>G (p.Trp101Gly)
c.362T>G (p.Leu121Arg)
c.383T>G (p.Leu128Arg)
c.191T>G (p.Leu64Arg)
c.395T>G (p.Leu132Arg)
c.263T>G
c.-15T>G (n.-15T>G)
c.398T>G (p.Leu133Arg)
c.283+1987T>G (n.283+1987T>G)
c.173+3232T>G (n.173+3232T>G)
c.174T>G
c.385T>G (p.Trp129Gly)
n.1089T>G
16g.31091325A>GCA395730041VKORC1c.301T>C (p.Trp101Arg)
c.362T>C (p.Leu121Pro)
c.383T>C (p.Leu128Pro)
c.191T>C (p.Leu64Pro)
c.395T>C (p.Leu132Pro)
c.263T>C
c.-15T>C (n.-15T>C)
c.398T>C (p.Leu133Pro)
c.283+1987T>C (n.283+1987T>C)
c.173+3232T>C (n.173+3232T>C)
c.174T>C
c.385T>C (p.Trp129Arg)
n.1089T>C
16g.31091325A>TCA395730042VKORC1c.301T>A (p.Trp101Arg)
c.362T>A (p.Leu121Gln)
c.383T>A (p.Leu128Gln)
c.191T>A (p.Leu64Gln)
c.395T>A (p.Leu132Gln)
c.263T>A
c.-15T>A (n.-15T>A)
c.398T>A (p.Leu133Gln)
c.283+1987T>A (n.283+1987T>A)
c.173+3232T>A (n.173+3232T>A)
c.174T>A
c.385T>A (p.Trp129Arg)
n.1089T>A
16g.31091326G>ACA494926036VKORC1c.300C>T (p.Arg100=)
c.361C>T (p.Leu121=)
c.382C>T (p.Leu128=)
c.190C>T (p.Leu64=)
c.394C>T (p.Leu132=)
c.262C>T
c.-16C>T (n.-16C>T)
c.397C>T (p.Leu133=)
c.283+1986C>T (n.283+1986C>T)
c.173+3231C>T (n.173+3231C>T)
c.173C>T
c.384C>T (p.Arg128=)
n.1088C>T
16g.31091326G>CCA395730044VKORC1c.300C>G (p.Arg100=)
c.361C>G (p.Leu121Val)
c.382C>G (p.Leu128Val)
c.190C>G (p.Leu64Val)
c.394C>G (p.Leu132Val)
c.262C>G
c.-16C>G (n.-16C>G)
c.397C>G (p.Leu133Val)
c.283+1986C>G (n.283+1986C>G)
c.173+3231C>G (n.173+3231C>G)
c.173C>G
c.384C>G (p.Arg128=)
n.1088C>G
16g.31091326G>TCA395730046VKORC1c.300C>A (p.Arg100=)
c.361C>A (p.Leu121Met)
c.382C>A (p.Leu128Met)
c.190C>A (p.Leu64Met)
c.394C>A (p.Leu132Met)
c.262C>A
c.-16C>A (n.-16C>A)
c.397C>A (p.Leu133Met)
c.283+1986C>A (n.283+1986C>A)
c.173+3231C>A (n.173+3231C>A)
c.173C>A
c.384C>A (p.Arg128=)
n.1088C>A
 gnomAD v4
16g.31091327C>ACA395730048VKORC1c.299G>T (p.Arg100Leu)
c.360G>T (p.Thr120=)
c.381G>T (p.Thr127=)
c.189G>T (p.Thr63=)
c.393G>T (p.Thr131=)
c.261G>T
c.-17G>T (n.-17G>T)
c.396G>T (p.Thr132=)
c.283+1985G>T (n.283+1985G>T)
c.173+3230G>T (n.173+3230G>T)
c.172G>T
c.383G>T (p.Arg128Leu)
n.1087G>T
 gnomAD v4
16g.31091327C=CA2216889300VKORC1c.299G= (p.Arg100=)
c.360G= (p.Thr120=)
c.381G= (p.Thr127=)
c.189G= (p.Thr63=)
c.393G= (p.Thr131=)
c.261G=
c.-17G= (n.-17G=)
c.396G= (p.Thr132=)
c.283+1985G= (n.283+1985G=)
c.173+3230G= (n.173+3230G=)
c.172G=
c.383G= (p.Arg128=)
n.1087G=
16g.31091327C>GCA395730050VKORC1c.299G>C (p.Arg100Pro)
c.360G>C (p.Thr120=)
c.381G>C (p.Thr127=)
c.189G>C (p.Thr63=)
c.393G>C (p.Thr131=)
c.261G>C
c.-17G>C (n.-17G>C)
c.396G>C (p.Thr132=)
c.283+1985G>C (n.283+1985G>C)
c.173+3230G>C (n.173+3230G>C)
c.172G>C
c.383G>C (p.Arg128Pro)
n.1087G>C
16g.31091327C>TCA395730052VKORC1c.299G>A (p.Arg100His)
c.360G>A (p.Thr120=)
c.381G>A (p.Thr127=)
c.189G>A (p.Thr63=)
c.393G>A (p.Thr131=)
c.261G>A
c.-17G>A (n.-17G>A)
c.396G>A (p.Thr132=)
c.283+1985G>A (n.283+1985G>A)
c.173+3230G>A (n.173+3230G>A)
c.172G>A
c.383G>A (p.Arg128His)
n.1087G>A
 dbSNP gnomAD v2 gnomAD v4
16g.31091328G>ACA8021133VKORC1c.298C>T (p.Arg100Cys)
c.359C>T (p.Thr120Met)
c.380C>T (p.Thr127Met)
c.188C>T (p.Thr63Met)
c.392C>T (p.Thr131Met)
c.260C>T
c.-18C>T (n.-18C>T)
c.395C>T (p.Thr132Met)
c.283+1984C>T (n.283+1984C>T)
c.173+3229C>T (n.173+3229C>T)
c.171C>T
c.382C>T (p.Arg128Cys)
n.1086C>T
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
16g.31091328G>CCA395730054VKORC1c.298C>G (p.Arg100Gly)
c.359C>G (p.Thr120Arg)
c.380C>G (p.Thr127Arg)
c.188C>G (p.Thr63Arg)
c.392C>G (p.Thr131Arg)
c.260C>G
c.-18C>G (n.-18C>G)
c.395C>G (p.Thr132Arg)
c.283+1984C>G (n.283+1984C>G)
c.173+3229C>G (n.173+3229C>G)
c.171C>G
c.382C>G (p.Arg128Gly)
n.1086C>G
16g.31091328G=CA2216889304VKORC1c.298C= (p.Arg100=)
c.359C= (p.Thr120=)
c.380C= (p.Thr127=)
c.188C= (p.Thr63=)
c.392C= (p.Thr131=)
c.260C=
c.-18C= (n.-18C=)
c.395C= (p.Thr132=)
c.283+1984C= (n.283+1984C=)
c.173+3229C= (n.173+3229C=)
c.171C=
c.382C= (p.Arg128=)
n.1086C=
16g.31091328G>TCA395730056VKORC1c.298C>A (p.Arg100Ser)
c.359C>A (p.Thr120Lys)
c.380C>A (p.Thr127Lys)
c.188C>A (p.Thr63Lys)
c.392C>A (p.Thr131Lys)
c.260C>A
c.-18C>A (n.-18C>A)
c.395C>A (p.Thr132Lys)
c.283+1984C>A (n.283+1984C>A)
c.173+3229C>A (n.173+3229C>A)
c.171C>A
c.382C>A (p.Arg128Ser)
n.1086C>A
16g.31091329T>ACA395730061VKORC1c.297A>T (p.Thr99=)
c.358A>T (p.Thr120Ser)
c.379A>T (p.Thr127Ser)
c.187A>T (p.Thr63Ser)
c.391A>T (p.Thr131Ser)
c.259A>T
c.-19A>T (n.-19A>T)
c.394A>T (p.Thr132Ser)
c.283+1983A>T (n.283+1983A>T)
c.173+3228A>T (n.173+3228A>T)
c.170A>T
c.381A>T (p.Thr127=)
n.1085A>T
16g.31091329T>CCA395730059VKORC1c.297A>G (p.Thr99=)
c.358A>G (p.Thr120Ala)
c.379A>G (p.Thr127Ala)
c.187A>G (p.Thr63Ala)
c.391A>G (p.Thr131Ala)
c.259A>G
c.-19A>G (n.-19A>G)
c.394A>G (p.Thr132Ala)
c.283+1983A>G (n.283+1983A>G)
c.173+3228A>G (n.173+3228A>G)
c.170A>G
c.381A>G (p.Thr127=)
n.1085A>G
16g.31091329T>GCA395730057VKORC1c.297A>C (p.Thr99=)
c.358A>C (p.Thr120Pro)
c.379A>C (p.Thr127Pro)
c.187A>C (p.Thr63Pro)
c.391A>C (p.Thr131Pro)
c.259A>C
c.-19A>C (n.-19A>C)
c.394A>C (p.Thr132Pro)
c.283+1983A>C (n.283+1983A>C)
c.173+3228A>C (n.173+3228A>C)
c.170A>C
c.381A>C (p.Thr127=)
n.1085A>C
16g.31091330G>ACA395730063VKORC1c.296C>T (p.Thr99Ile)
c.357C>T (p.Asp119=)
c.378C>T (p.Asp126=)
c.186C>T (p.Asp62=)
c.390C>T (p.Asp130=)
c.258C>T
c.-20C>T (n.-20C>T)
c.393C>T (p.Asp131=)
c.283+1982C>T (n.283+1982C>T)
c.173+3227C>T (n.173+3227C>T)
c.169C>T
c.380C>T (p.Thr127Ile)
n.1084C>T
16g.31091330G>CCA280620007VKORC1c.296C>G (p.Thr99Arg)
c.357C>G (p.Asp119Glu)
c.378C>G (p.Asp126Glu)
c.186C>G (p.Asp62Glu)
c.390C>G (p.Asp130Glu)
c.258C>G
c.-20C>G (n.-20C>G)
c.393C>G (p.Asp131Glu)
c.283+1982C>G (n.283+1982C>G)
c.173+3227C>G (n.173+3227C>G)
c.169C>G
c.380C>G (p.Thr127Arg)
n.1084C>G
 dbSNP gnomAD v4
16g.31091330G=CA2216889306VKORC1c.296C= (p.Thr99=)
c.357C= (p.Asp119=)
c.378C= (p.Asp126=)
c.186C= (p.Asp62=)
c.390C= (p.Asp130=)
c.258C=
c.-20C= (n.-20C=)
c.393C= (p.Asp131=)
c.283+1982C= (n.283+1982C=)
c.173+3227C= (n.173+3227C=)
c.169C=
c.380C= (p.Thr127=)
n.1084C=
16g.31091330G>TCA280620014VKORC1c.296C>A (p.Thr99Lys)
c.357C>A (p.Asp119Glu)
c.378C>A (p.Asp126Glu)
c.186C>A (p.Asp62Glu)
c.390C>A (p.Asp130Glu)
c.258C>A
c.-20C>A (n.-20C>A)
c.393C>A (p.Asp131Glu)
c.283+1982C>A (n.283+1982C>A)
c.173+3227C>A (n.173+3227C>A)
c.169C>A
c.380C>A (p.Thr127Lys)
n.1084C>A
 dbSNP gnomAD v3 gnomAD v4
16g.31091331T>ACA395730066VKORC1c.295A>T (p.Thr99Ser)
c.356A>T (p.Asp119Val)
c.377A>T (p.Asp126Val)
c.185A>T (p.Asp62Val)
c.389A>T (p.Asp130Val)
c.257A>T
c.-21A>T (n.-21A>T)
c.392A>T (p.Asp131Val)
c.283+1981A>T (n.283+1981A>T)
c.173+3226A>T (n.173+3226A>T)
c.168A>T
c.379A>T (p.Thr127Ser)
n.1083A>T
16g.31091331T>CCA395730068VKORC1c.295A>G (p.Thr99Ala)
c.356A>G (p.Asp119Gly)
c.377A>G (p.Asp126Gly)
c.185A>G (p.Asp62Gly)
c.389A>G (p.Asp130Gly)
c.257A>G
c.-21A>G (n.-21A>G)
c.392A>G (p.Asp131Gly)
c.283+1981A>G (n.283+1981A>G)
c.173+3226A>G (n.173+3226A>G)
c.168A>G
c.379A>G (p.Thr127Ala)
n.1083A>G
16g.31091331T>GCA395730069VKORC1c.295A>C (p.Thr99Pro)
c.356A>C (p.Asp119Ala)
c.377A>C (p.Asp126Ala)
c.185A>C (p.Asp62Ala)
c.389A>C (p.Asp130Ala)
c.257A>C
c.-21A>C (n.-21A>C)
c.392A>C (p.Asp131Ala)
c.283+1981A>C (n.283+1981A>C)
c.173+3226A>C (n.173+3226A>C)
c.168A>C
c.379A>C (p.Thr127Pro)
n.1083A>C
16g.31091332C>ACA395730071VKORC1c.294G>T (p.Arg98=)
c.355G>T (p.Asp119Tyr)
c.376G>T (p.Asp126Tyr)
c.184G>T (p.Asp62Tyr)
c.388G>T (p.Asp130Tyr)
c.256G>T
c.-22G>T (n.-22G>T)
c.391G>T (p.Asp131Tyr)
c.283+1980G>T (n.283+1980G>T)
c.173+3225G>T (n.173+3225G>T)
c.167G>T
c.378G>T (p.Arg126=)
n.1082G>T
16g.31091332C>GCA395730073VKORC1c.294G>C (p.Arg98=)
c.355G>C (p.Asp119His)
c.376G>C (p.Asp126His)
c.184G>C (p.Asp62His)
c.388G>C (p.Asp130His)
c.256G>C
c.-22G>C (n.-22G>C)
c.391G>C (p.Asp131His)
c.283+1980G>C (n.283+1980G>C)
c.173+3225G>C (n.173+3225G>C)
c.167G>C
c.378G>C (p.Arg126=)
n.1082G>C
16g.31091332C>TCA395730074VKORC1c.294G>A (p.Arg98=)
c.355G>A (p.Asp119Asn)
c.376G>A (p.Asp126Asn)
c.184G>A (p.Asp62Asn)
c.388G>A (p.Asp130Asn)
c.256G>A
c.-22G>A (n.-22G>A)
c.391G>A (p.Asp131Asn)
c.283+1980G>A (n.283+1980G>A)
c.173+3225G>A (n.173+3225G>A)
c.167G>A
c.378G>A (p.Arg126=)
n.1082G>A
16g.31091333C>ACA395730076VKORC1c.293G>T (p.Arg98Leu)
c.354G>T (p.Ala118=)
c.375G>T (p.Ala125=)
c.183G>T (p.Ala61=)
c.387G>T (p.Ala129=)
c.255G>T
c.-23G>T (n.-23G>T)
c.390G>T (p.Ala130=)
c.283+1979G>T (n.283+1979G>T)
c.173+3224G>T (n.173+3224G>T)
c.166G>T
c.377G>T (p.Arg126Leu)
n.1081G>T
16g.31091333C=CA2216889308VKORC1c.293G= (p.Arg98=)
c.354G= (p.Ala118=)
c.375G= (p.Ala125=)
c.183G= (p.Ala61=)
c.387G= (p.Ala129=)
c.255G=
c.-23G= (n.-23G=)
c.390G= (p.Ala130=)
c.283+1979G= (n.283+1979G=)
c.173+3224G= (n.173+3224G=)
c.166G=
c.377G= (p.Arg126=)
n.1081G=
16g.31091333C>GCA395730078VKORC1c.293G>C (p.Arg98Pro)
c.354G>C (p.Ala118=)
c.375G>C (p.Ala125=)
c.183G>C (p.Ala61=)
c.387G>C (p.Ala129=)
c.255G>C
c.-23G>C (n.-23G>C)
c.390G>C (p.Ala130=)
c.283+1979G>C (n.283+1979G>C)
c.173+3224G>C (n.173+3224G>C)
c.166G>C
c.377G>C (p.Arg126Pro)
n.1081G>C
 dbSNP gnomAD v4
16g.31091333C>TCA395730080VKORC1c.293G>A (p.Arg98Gln)
c.354G>A (p.Ala118=)
c.375G>A (p.Ala125=)
c.183G>A (p.Ala61=)
c.387G>A (p.Ala129=)
c.255G>A
c.-23G>A (n.-23G>A)
c.390G>A (p.Ala130=)
c.283+1979G>A (n.283+1979G>A)
c.173+3224G>A (n.173+3224G>A)
c.166G>A
c.377G>A (p.Arg126Gln)
n.1081G>A
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
16g.31091333_31091334delinsCGCA2216889310VKORC1c.292_293delinsCG (p.Arg98=)
c.353_354delinsCG (p.Ala118=)
c.374_375delinsCG (p.Ala125=)
c.182_183delinsCG (p.Ala61=)
c.386_387delinsCG (p.Ala129=)
c.254_255delinsCG
c.-24_-23delinsCG (n.-24_-23delinsCG)
c.389_390delinsCG (p.Ala130=)
c.283+1978_283+1979delinsCG (n.283+1978_283+1979delinsCG)
c.173+3223_173+3224delinsCG (n.173+3223_173+3224delinsCG)
c.165_166delinsCG
c.376_377delinsCG (p.Arg126=)
n.1080_1081delinsCG
16g.31091334delCA2216889316VKORC1c.292del (p.Arg98GlyfsTer8)
c.353del (p.Ala118GlyfsTer?)
c.374del (p.Ala125GlyfsTer?)
c.182del (p.Ala61GlyfsTer?)
c.386del (p.Ala129GlyfsTer?)
c.254del
c.-24del (n.-24del)
c.389del (p.Ala130GlyfsTer?)
c.283+1978del (n.283+1978del)
c.173+3223del (n.173+3223del)
c.165del
c.376del (p.Arg126GlyfsTer8)
n.1080del
 dbSNP
16g.31091334G>ACA115411VKORC1c.292C>T (p.Arg98Trp)
c.353C>T (p.Ala118Val)
c.374C>T (p.Ala125Val)
c.182C>T (p.Ala61Val)
c.386C>T (p.Ala129Val)
c.254C>T
c.-24C>T (n.-24C>T)
c.389C>T (p.Ala130Val)
c.283+1978C>T (n.283+1978C>T)
c.173+3223C>T (n.173+3223C>T)
c.165C>T
c.376C>T (p.Arg126Trp)
n.1080C>T
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4 COSMIC
16g.31091334G>CCA8021134VKORC1c.292C>G (p.Arg98Gly)
c.353C>G (p.Ala118Gly)
c.374C>G (p.Ala125Gly)
c.182C>G (p.Ala61Gly)
c.386C>G (p.Ala129Gly)
c.254C>G
c.-24C>G (n.-24C>G)
c.389C>G (p.Ala130Gly)
c.283+1978C>G (n.283+1978C>G)
c.173+3223C>G (n.173+3223C>G)
c.165C>G
c.376C>G (p.Arg126Gly)
n.1080C>G
 dbSNP ExAC gnomAD v2 gnomAD v4
16g.31091334G=CA2216889318VKORC1c.292C= (p.Arg98=)
c.353C= (p.Ala118=)
c.374C= (p.Ala125=)
c.182C= (p.Ala61=)
c.386C= (p.Ala129=)
c.254C=
c.-24C= (n.-24C=)
c.389C= (p.Ala130=)
c.283+1978C= (n.283+1978C=)
c.173+3223C= (n.173+3223C=)
c.165C=
c.376C= (p.Arg126=)
n.1080C=
16g.31091334G>TCA395730082VKORC1c.292C>A (p.Arg98=)
c.353C>A (p.Ala118Glu)
c.374C>A (p.Ala125Glu)
c.182C>A (p.Ala61Glu)
c.386C>A (p.Ala129Glu)
c.254C>A
c.-24C>A (n.-24C>A)
c.389C>A (p.Ala130Glu)
c.283+1978C>A (n.283+1978C>A)
c.173+3223C>A (n.173+3223C>A)
c.165C>A
c.376C>A (p.Arg126=)
n.1080C>A
16g.31091335C>ACA395730086VKORC1c.291G>T (p.Leu97=)
c.352G>T (p.Ala118Ser)
c.373G>T (p.Ala125Ser)
c.181G>T (p.Ala61Ser)
c.385G>T (p.Ala129Ser)
c.253G>T
c.-25G>T (n.-25G>T)
c.388G>T (p.Ala130Ser)
c.283+1977G>T (n.283+1977G>T)
c.173+3222G>T (n.173+3222G>T)
c.164G>T
c.375G>T (p.Leu125=)
n.1079G>T
16g.31091335C=CA2216889323VKORC1c.291G= (p.Leu97=)
c.352G= (p.Ala118=)
c.373G= (p.Ala125=)
c.181G= (p.Ala61=)
c.385G= (p.Ala129=)
c.253G=
c.-25G= (n.-25G=)
c.388G= (p.Ala130=)
c.283+1977G= (n.283+1977G=)
c.173+3222G= (n.173+3222G=)
c.164G=
c.375G= (p.Leu125=)
n.1079G=
16g.31091335C>GCA395730088VKORC1c.291G>C (p.Leu97=)
c.352G>C (p.Ala118Pro)
c.373G>C (p.Ala125Pro)
c.181G>C (p.Ala61Pro)
c.385G>C (p.Ala129Pro)
c.253G>C
c.-25G>C (n.-25G>C)
c.388G>C (p.Ala130Pro)
c.283+1977G>C (n.283+1977G>C)
c.173+3222G>C (n.173+3222G>C)
c.164G>C
c.375G>C (p.Leu125=)
n.1079G>C
16g.31091335C>TCA8021135VKORC1c.291G>A (p.Leu97=)
c.352G>A (p.Ala118Thr)
c.373G>A (p.Ala125Thr)
c.181G>A (p.Ala61Thr)
c.385G>A (p.Ala129Thr)
c.253G>A
c.-25G>A (n.-25G>A)
c.388G>A (p.Ala130Thr)
c.283+1977G>A (n.283+1977G>A)
c.173+3222G>A (n.173+3222G>A)
c.164G>A
c.375G>A (p.Leu125=)
n.1079G>A
 dbSNP ExAC gnomAD v2 gnomAD v4
16g.31091336A>CCA395730090VKORC1c.290T>G (p.Leu97Arg)
c.351T>G (p.Pro117=)
c.372T>G (p.Pro124=)
c.180T>G (p.Pro60=)
c.384T>G (p.Pro128=)
c.252T>G
c.-26T>G (n.-26T>G)
c.387T>G (p.Pro129=)
c.283+1976T>G (n.283+1976T>G)
c.173+3221T>G (n.173+3221T>G)
c.163T>G
c.374T>G (p.Leu125Arg)
n.1078T>G
16g.31091336A>GCA395730092VKORC1c.290T>C (p.Leu97Pro)
c.351T>C (p.Pro117=)
c.372T>C (p.Pro124=)
c.180T>C (p.Pro60=)
c.384T>C (p.Pro128=)
c.252T>C
c.-26T>C (n.-26T>C)
c.387T>C (p.Pro129=)
c.283+1976T>C (n.283+1976T>C)
c.173+3221T>C (n.173+3221T>C)
c.163T>C
c.374T>C (p.Leu125Pro)
n.1078T>C
16g.31091336A>TCA395730094VKORC1c.290T>A (p.Leu97Gln)
c.351T>A (p.Pro117=)
c.372T>A (p.Pro124=)
c.180T>A (p.Pro60=)
c.384T>A (p.Pro128=)
c.252T>A
c.-26T>A (n.-26T>A)
c.387T>A (p.Pro129=)
c.283+1976T>A (n.283+1976T>A)
c.173+3221T>A (n.173+3221T>A)
c.163T>A
c.374T>A (p.Leu125Gln)
n.1078T>A
16g.31091337G>ACA8021136VKORC1c.289C>T (p.Leu97=)
c.350C>T (p.Pro117Leu)
c.371C>T (p.Pro124Leu)
c.179C>T (p.Pro60Leu)
c.383C>T (p.Pro128Leu)
c.251C>T
c.-27C>T (n.-27C>T)
c.386C>T (p.Pro129Leu)
c.283+1975C>T (n.283+1975C>T)
c.173+3220C>T (n.173+3220C>T)
c.162C>T
c.373C>T (p.Leu125=)
n.1077C>T
 dbSNP ExAC gnomAD v2
16g.31091337G>CCA395730096VKORC1c.289C>G (p.Leu97Val)
c.350C>G (p.Pro117Arg)
c.371C>G (p.Pro124Arg)
c.179C>G (p.Pro60Arg)
c.383C>G (p.Pro128Arg)
c.251C>G
c.-27C>G (n.-27C>G)
c.386C>G (p.Pro129Arg)
c.283+1975C>G (n.283+1975C>G)
c.173+3220C>G (n.173+3220C>G)
c.162C>G
c.373C>G (p.Leu125Val)
n.1077C>G
 gnomAD v4
16g.31091337G=CA2216889326VKORC1c.289C= (p.Leu97=)
c.350C= (p.Pro117=)
c.371C= (p.Pro124=)
c.179C= (p.Pro60=)
c.383C= (p.Pro128=)
c.251C=
c.-27C= (n.-27C=)
c.386C= (p.Pro129=)
c.283+1975C= (n.283+1975C=)
c.173+3220C= (n.173+3220C=)
c.162C=
c.373C= (p.Leu125=)
n.1077C=
16g.31091337G>TCA395730099VKORC1c.289C>A (p.Leu97Met)
c.350C>A (p.Pro117His)
c.371C>A (p.Pro124His)
c.179C>A (p.Pro60His)
c.383C>A (p.Pro128His)
c.251C>A
c.-27C>A (n.-27C>A)
c.386C>A (p.Pro129His)
c.283+1975C>A (n.283+1975C>A)
c.173+3220C>A (n.173+3220C>A)
c.162C>A
c.373C>A (p.Leu125Met)
n.1077C>A
16g.31091338G>ACA395730100VKORC1c.288C>T (p.Cys96=)
c.349C>T (p.Pro117Ser)
c.370C>T (p.Pro124Ser)
c.178C>T (p.Pro60Ser)
c.382C>T (p.Pro128Ser)
c.250C>T
c.-28C>T (n.-28C>T)
c.385C>T (p.Pro129Ser)
c.283+1974C>T (n.283+1974C>T)
c.173+3219C>T (n.173+3219C>T)
c.161C>T
c.372C>T (p.Cys124=)
n.1076C>T
 gnomAD v4
16g.31091338G>CCA395730102VKORC1c.288C>G (p.Cys96Trp)
c.349C>G (p.Pro117Ala)
c.370C>G (p.Pro124Ala)
c.178C>G (p.Pro60Ala)
c.382C>G (p.Pro128Ala)
c.250C>G
c.-28C>G (n.-28C>G)
c.385C>G (p.Pro129Ala)
c.283+1974C>G (n.283+1974C>G)
c.173+3219C>G (n.173+3219C>G)
c.161C>G
c.372C>G (p.Cys124Trp)
n.1076C>G
16g.31091338G>TCA395730104VKORC1c.288C>A (p.Cys96Ter)
c.349C>A (p.Pro117Thr)
c.370C>A (p.Pro124Thr)
c.178C>A (p.Pro60Thr)
c.382C>A (p.Pro128Thr)
c.250C>A
c.-28C>A (n.-28C>A)
c.385C>A (p.Pro129Thr)
c.283+1974C>A (n.283+1974C>A)
c.173+3219C>A (n.173+3219C>A)
c.161C>A
c.372C>A (p.Cys124Ter)
n.1076C>A
16g.31091339C>ACA395730108VKORC1c.287G>T (p.Cys96Phe)
c.348G>T (p.Leu116Phe)
c.369G>T (p.Leu123Phe)
c.177G>T (p.Leu59Phe)
c.381G>T (p.Leu127Phe)
c.249G>T
c.-29G>T (n.-29G>T)
c.384G>T (p.Leu128Phe)
c.283+1973G>T (n.283+1973G>T)
c.173+3218G>T (n.173+3218G>T)
c.160G>T
c.371G>T (p.Cys124Phe)
n.1075G>T
16g.31091339C>GCA395730109VKORC1c.287G>C (p.Cys96Ser)
c.348G>C (p.Leu116Phe)
c.369G>C (p.Leu123Phe)
c.177G>C (p.Leu59Phe)
c.381G>C (p.Leu127Phe)
c.249G>C
c.-29G>C (n.-29G>C)
c.384G>C (p.Leu128Phe)
c.283+1973G>C (n.283+1973G>C)
c.173+3218G>C (n.173+3218G>C)
c.160G>C
c.371G>C (p.Cys124Ser)
n.1075G>C
16g.31091339C>TCA395730106VKORC1c.287G>A (p.Cys96Tyr)
c.348G>A (p.Leu116=)
c.369G>A (p.Leu123=)
c.177G>A (p.Leu59=)
c.381G>A (p.Leu127=)
c.249G>A
c.-29G>A (n.-29G>A)
c.384G>A (p.Leu128=)
c.283+1973G>A (n.283+1973G>A)
c.173+3218G>A (n.173+3218G>A)
c.160G>A
c.371G>A (p.Cys124Tyr)
n.1075G>A

Number of alleles fetched