Allele Registry

Chr	Mutation (hg38)	CAid	Gene	Transcript	Linkouts
2	g.224503688_224503715delinsTGTGAGA	CA2580617718	CUL3	c.1314_1341delinsTCTCACA (p.Arg438_Ser447delinsSerLeuThr) c.1116_1143delinsTCTCACA (p.Arg372_Ser381delinsSerLeuThr) c.1242_1269delinsTCTCACA (p.Arg414_Ser423delinsSerLeuThr) n.610_637delinsTCTCACA c.38_65delinsTCTCACA (p.Gly13_Leu22delinsValSerGln) c.1332_1359delinsTCTCACA (p.Arg444_Ser453delinsSerLeuThr) c.1281_1308delinsTCTCACA (p.Arg427_Ser436delinsSerLeuThr) c.1167_1194delinsTCTCACA (p.Arg389_Ser398delinsSerLeuThr) c.1272_1299delinsTCTCACA (p.Arg424_Ser433delinsSerLeuThr) c.1122_1149delinsTCTCACA (p.Arg374_Ser383delinsSerLeuThr) c.1014_1041delinsTCTCACA (p.Arg338_Ser347delinsSerLeuThr)	ClinVar
2	g.224503695_224503700delinsCTTTTA	CA1331555935	CUL3	c.1329_1334delinsTAAAAG (p.Asn443=) c.1131_1136delinsTAAAAG (p.Asn377=) c.1257_1262delinsTAAAAG (p.Asn419=) n.625_630delinsTAAAAG c.53_58delinsTAAAAG (p.Ile18=) c.1347_1352delinsTAAAAG (p.Asn449=) c.1296_1301delinsTAAAAG (p.Asn432=) c.1182_1187delinsTAAAAG (p.Asn394=) c.1287_1292delinsTAAAAG (p.Asn429=) c.1137_1142delinsTAAAAG (p.Asn379=) c.1029_1034delinsTAAAAG (p.Asn343=)
2	g.224503699_224503703del	CA2140017	CUL3	c.1329_1333del (p.Asn443LysfsTer4) c.1131_1135del (p.Asn377LysfsTer4) c.1257_1261del (p.Asn419LysfsTer4) n.625_629del c.53_57del (p.Ile18SerfsTer12) c.1347_1351del (p.Asn449LysfsTer4) c.1296_1300del (p.Asn432LysfsTer4) c.1182_1186del (p.Asn394LysfsTer4) c.1287_1291del (p.Asn429LysfsTer4) c.1137_1141del (p.Asn379LysfsTer4) c.1029_1033del (p.Asn343LysfsTer4)	dbSNP ExAC gnomAD v2 gnomAD v4
2	g.224503700A>C	CA350827175	CUL3	c.1329T>G (p.Asn443Lys) c.1131T>G (p.Asn377Lys) c.1257T>G (p.Asn419Lys) n.625T>G c.53T>G (p.Ile18Arg) c.1347T>G (p.Asn449Lys) c.1296T>G (p.Asn432Lys) c.1182T>G (p.Asn394Lys) c.1287T>G (p.Asn429Lys) c.1137T>G (p.Asn379Lys) c.1029T>G (p.Asn343Lys)
2	g.224503700A>G	CA350827179	CUL3	c.1329T>C (p.Asn443=) c.1131T>C (p.Asn377=) c.1257T>C (p.Asn419=) n.625T>C c.53T>C (p.Ile18Thr) c.1347T>C (p.Asn449=) c.1296T>C (p.Asn432=) c.1182T>C (p.Asn394=) c.1287T>C (p.Asn429=) c.1137T>C (p.Asn379=) c.1029T>C (p.Asn343=)
2	g.224503700A>T	CA350827182	CUL3	c.1329T>A (p.Asn443Lys) c.1131T>A (p.Asn377Lys) c.1257T>A (p.Asn419Lys) n.625T>A c.53T>A (p.Ile18Lys) c.1347T>A (p.Asn449Lys) c.1296T>A (p.Asn432Lys) c.1182T>A (p.Asn394Lys) c.1287T>A (p.Asn429Lys) c.1137T>A (p.Asn379Lys) c.1029T>A (p.Asn343Lys)
2	g.224503701T>A	CA350827185	CUL3	c.1328A>T (p.Asn443Ile) c.1130A>T (p.Asn377Ile) c.1256A>T (p.Asn419Ile) n.624A>T c.52A>T (p.Ile18Leu) c.1346A>T (p.Asn449Ile) c.1295A>T (p.Asn432Ile) c.1181A>T (p.Asn394Ile) c.1286A>T (p.Asn429Ile) c.1136A>T (p.Asn379Ile) c.1028A>T (p.Asn343Ile)	dbSNP
2	g.224503701T>C	CA350827190	CUL3	c.1328A>G (p.Asn443Ser) c.1130A>G (p.Asn377Ser) c.1256A>G (p.Asn419Ser) n.624A>G c.52A>G (p.Ile18Val) c.1346A>G (p.Asn449Ser) c.1295A>G (p.Asn432Ser) c.1181A>G (p.Asn394Ser) c.1286A>G (p.Asn429Ser) c.1136A>G (p.Asn379Ser) c.1028A>G (p.Asn343Ser)	gnomAD v4
2	g.224503701T>G	CA350827187	CUL3	c.1328A>C (p.Asn443Thr) c.1130A>C (p.Asn377Thr) c.1256A>C (p.Asn419Thr) n.624A>C c.52A>C (p.Ile18Leu) c.1346A>C (p.Asn449Thr) c.1295A>C (p.Asn432Thr) c.1181A>C (p.Asn394Thr) c.1286A>C (p.Asn429Thr) c.1136A>C (p.Asn379Thr) c.1028A>C (p.Asn343Thr)
2	g.224503702T>A	CA350827195	CUL3	c.1327A>T (p.Asn443Tyr) c.1129A>T (p.Asn377Tyr) c.1255A>T (p.Asn419Tyr) n.623A>T c.51A>T (p.Gln17His) c.1345A>T (p.Asn449Tyr) c.1294A>T (p.Asn432Tyr) c.1180A>T (p.Asn394Tyr) c.1285A>T (p.Asn429Tyr) c.1135A>T (p.Asn379Tyr) c.1027A>T (p.Asn343Tyr)
2	g.224503702T>C	CA350827197	CUL3	c.1327A>G (p.Asn443Asp) c.1129A>G (p.Asn377Asp) c.1255A>G (p.Asn419Asp) n.623A>G c.51A>G (p.Gln17=) c.1345A>G (p.Asn449Asp) c.1294A>G (p.Asn432Asp) c.1180A>G (p.Asn394Asp) c.1285A>G (p.Asn429Asp) c.1135A>G (p.Asn379Asp) c.1027A>G (p.Asn343Asp)	dbSNP
2	g.224503702T>G	CA350827199	CUL3	c.1327A>C (p.Asn443His) c.1129A>C (p.Asn377His) c.1255A>C (p.Asn419His) n.623A>C c.51A>C (p.Gln17His) c.1345A>C (p.Asn449His) c.1294A>C (p.Asn432His) c.1180A>C (p.Asn394His) c.1285A>C (p.Asn429His) c.1135A>C (p.Asn379His) c.1027A>C (p.Asn343His)
2	g.224503703T>A	CA350827202	CUL3	c.1326A>T (p.Thr442=) c.1128A>T (p.Thr376=) c.1254A>T (p.Thr418=) n.622A>T c.50A>T (p.Gln17Leu) c.1344A>T (p.Thr448=) c.1293A>T (p.Thr431=) c.1179A>T (p.Thr393=) c.1284A>T (p.Thr428=) c.1134A>T (p.Thr378=) c.1026A>T (p.Thr342=)
2	g.224503703T>C	CA350827205	CUL3	c.1326A>G (p.Thr442=) c.1128A>G (p.Thr376=) c.1254A>G (p.Thr418=) n.622A>G c.50A>G (p.Gln17Arg) c.1344A>G (p.Thr448=) c.1293A>G (p.Thr431=) c.1179A>G (p.Thr393=) c.1284A>G (p.Thr428=) c.1134A>G (p.Thr378=) c.1026A>G (p.Thr342=)	dbSNP gnomAD v3 gnomAD v4
2	g.224503703T>G	CA350827207	CUL3	c.1326A>C (p.Thr442=) c.1128A>C (p.Thr376=) c.1254A>C (p.Thr418=) n.622A>C c.50A>C (p.Gln17Pro) c.1344A>C (p.Thr448=) c.1293A>C (p.Thr431=) c.1179A>C (p.Thr393=) c.1284A>C (p.Thr428=) c.1134A>C (p.Thr378=) c.1026A>C (p.Thr342=)
2	g.224503703T=	CA1331555937	CUL3	c.1326A= (p.Thr442=) c.1128A= (p.Thr376=) c.1254A= (p.Thr418=) n.622A= c.50A= (p.Gln17=) c.1344A= (p.Thr448=) c.1293A= (p.Thr431=) c.1179A= (p.Thr393=) c.1284A= (p.Thr428=) c.1134A= (p.Thr378=) c.1026A= (p.Thr342=)
2	g.224503704G>A	CA350827211	CUL3	c.1325C>T (p.Thr442Ile) c.1127C>T (p.Thr376Ile) c.1253C>T (p.Thr418Ile) n.621C>T c.49C>T (p.Gln17Ter) c.1343C>T (p.Thr448Ile) c.1292C>T (p.Thr431Ile) c.1178C>T (p.Thr393Ile) c.1283C>T (p.Thr428Ile) c.1133C>T (p.Thr378Ile) c.1025C>T (p.Thr342Ile)	dbSNP
2	g.224503704G>C	CA350827214	CUL3	c.1325C>G (p.Thr442Arg) c.1127C>G (p.Thr376Arg) c.1253C>G (p.Thr418Arg) n.621C>G c.49C>G (p.Gln17Glu) c.1343C>G (p.Thr448Arg) c.1292C>G (p.Thr431Arg) c.1178C>G (p.Thr393Arg) c.1283C>G (p.Thr428Arg) c.1133C>G (p.Thr378Arg) c.1025C>G (p.Thr342Arg)	dbSNP COSMIC
2	g.224503704G>T	CA350827216	CUL3	c.1325C>A (p.Thr442Lys) c.1127C>A (p.Thr376Lys) c.1253C>A (p.Thr418Lys) n.621C>A c.49C>A (p.Gln17Lys) c.1343C>A (p.Thr448Lys) c.1292C>A (p.Thr431Lys) c.1178C>A (p.Thr393Lys) c.1283C>A (p.Thr428Lys) c.1133C>A (p.Thr378Lys) c.1025C>A (p.Thr342Lys)	dbSNP
2	g.224503704_224503705insGTAGATTATTAAG	CA2701737684	CUL3	c.1325_1326insTTAATAATCTACC (p.Asn443Ter) c.1127_1128insTTAATAATCTACC (p.Asn377Ter) c.1253_1254insTTAATAATCTACC (p.Asn419Ter) n.621_622insTTAATAATCTACC c.49_50insTTAATAATCTACC (p.Gln17LeufsTer19) c.1343_1344insTTAATAATCTACC (p.Asn449Ter) c.1292_1293insTTAATAATCTACC (p.Asn432Ter) c.1178_1179insTTAATAATCTACC (p.Asn394Ter) c.1283_1284insTTAATAATCTACC (p.Asn429Ter) c.1133_1134insTTAATAATCTACC (p.Asn379Ter) c.1025_1026insTTAATAATCTACC (p.Asn343Ter)	dbSNP
2	g.224503705T>A	CA350827220	CUL3	c.1324A>T (p.Thr442Ser) c.1126A>T (p.Thr376Ser) c.1252A>T (p.Thr418Ser) n.620A>T c.48A>T (p.Ser16=) c.1342A>T (p.Thr448Ser) c.1291A>T (p.Thr431Ser) c.1177A>T (p.Thr393Ser) c.1282A>T (p.Thr428Ser) c.1132A>T (p.Thr378Ser) c.1024A>T (p.Thr342Ser)	dbSNP
2	g.224503705T>C	CA350827223	CUL3	c.1324A>G (p.Thr442Ala) c.1126A>G (p.Thr376Ala) c.1252A>G (p.Thr418Ala) n.620A>G c.48A>G (p.Ser16=) c.1342A>G (p.Thr448Ala) c.1291A>G (p.Thr431Ala) c.1177A>G (p.Thr393Ala) c.1282A>G (p.Thr428Ala) c.1132A>G (p.Thr378Ala) c.1024A>G (p.Thr342Ala)
2	g.224503705T>G	CA350827225	CUL3	c.1324A>C (p.Thr442Pro) c.1126A>C (p.Thr376Pro) c.1252A>C (p.Thr418Pro) n.620A>C c.48A>C (p.Ser16=) c.1342A>C (p.Thr448Pro) c.1291A>C (p.Thr431Pro) c.1177A>C (p.Thr393Pro) c.1282A>C (p.Thr428Pro) c.1132A>C (p.Thr378Pro) c.1024A>C (p.Thr342Pro)
2	g.224503706G>A	CA350827233	CUL3	c.1323C>T (p.Leu441=) c.1125C>T (p.Leu375=) c.1251C>T (p.Leu417=) n.619C>T c.47C>T (p.Ser16Leu) c.1341C>T (p.Leu447=) c.1290C>T (p.Leu430=) c.1176C>T (p.Leu392=) c.1281C>T (p.Leu427=) c.1131C>T (p.Leu377=) c.1023C>T (p.Leu341=)	ClinVar dbSNP gnomAD v4
2	g.224503706G>C	CA350827229	CUL3	c.1323C>G (p.Leu441=) c.1125C>G (p.Leu375=) c.1251C>G (p.Leu417=) n.619C>G c.47C>G (p.Ser16Ter) c.1341C>G (p.Leu447=) c.1290C>G (p.Leu430=) c.1176C>G (p.Leu392=) c.1281C>G (p.Leu427=) c.1131C>G (p.Leu377=) c.1023C>G (p.Leu341=)
2	g.224503706G=	CA1331555938	CUL3	c.1323C= (p.Leu441=) c.1125C= (p.Leu375=) c.1251C= (p.Leu417=) n.619C= c.47C= (p.Ser16=) c.1341C= (p.Leu447=) c.1290C= (p.Leu430=) c.1176C= (p.Leu392=) c.1281C= (p.Leu427=) c.1131C= (p.Leu377=) c.1023C= (p.Leu341=)
2	g.224503706G>T	CA350827232	CUL3	c.1323C>A (p.Leu441=) c.1125C>A (p.Leu375=) c.1251C>A (p.Leu417=) n.619C>A c.47C>A (p.Ser16Ter) c.1341C>A (p.Leu447=) c.1290C>A (p.Leu430=) c.1176C>A (p.Leu392=) c.1281C>A (p.Leu427=) c.1131C>A (p.Leu377=) c.1023C>A (p.Leu341=)
2	g.224503707A>C	CA350827236	CUL3	c.1322T>G (p.Leu441Arg) c.1124T>G (p.Leu375Arg) c.1250T>G (p.Leu417Arg) n.618T>G c.46T>G (p.Ser16Ala) c.1340T>G (p.Leu447Arg) c.1289T>G (p.Leu430Arg) c.1175T>G (p.Leu392Arg) c.1280T>G (p.Leu427Arg) c.1130T>G (p.Leu377Arg) c.1022T>G (p.Leu341Arg)
2	g.224503707A>G	CA350827240	CUL3	c.1322T>C (p.Leu441Pro) c.1124T>C (p.Leu375Pro) c.1250T>C (p.Leu417Pro) n.618T>C c.46T>C (p.Ser16Pro) c.1340T>C (p.Leu447Pro) c.1289T>C (p.Leu430Pro) c.1175T>C (p.Leu392Pro) c.1280T>C (p.Leu427Pro) c.1130T>C (p.Leu377Pro) c.1022T>C (p.Leu341Pro)
2	g.224503707A>T	CA350827241	CUL3	c.1322T>A (p.Leu441His) c.1124T>A (p.Leu375His) c.1250T>A (p.Leu417His) n.618T>A c.46T>A (p.Ser16Thr) c.1340T>A (p.Leu447His) c.1289T>A (p.Leu430His) c.1175T>A (p.Leu392His) c.1280T>A (p.Leu427His) c.1130T>A (p.Leu377His) c.1022T>A (p.Leu341His)	dbSNP
2	g.224503708G>A	CA350827245	CUL3	c.1321C>T (p.Leu441Phe) c.1123C>T (p.Leu375Phe) c.1249C>T (p.Leu417Phe) n.617C>T c.45C>T (p.Phe15=) c.1339C>T (p.Leu447Phe) c.1288C>T (p.Leu430Phe) c.1174C>T (p.Leu392Phe) c.1279C>T (p.Leu427Phe) c.1129C>T (p.Leu377Phe) c.1021C>T (p.Leu341Phe)	dbSNP
2	g.224503708G>C	CA350827246	CUL3	c.1321C>G (p.Leu441Val) c.1123C>G (p.Leu375Val) c.1249C>G (p.Leu417Val) n.617C>G c.45C>G (p.Phe15Leu) c.1339C>G (p.Leu447Val) c.1288C>G (p.Leu430Val) c.1174C>G (p.Leu392Val) c.1279C>G (p.Leu427Val) c.1129C>G (p.Leu377Val) c.1021C>G (p.Leu341Val)	dbSNP
2	g.224503708G>T	CA350827249	CUL3	c.1321C>A (p.Leu441Ile) c.1123C>A (p.Leu375Ile) c.1249C>A (p.Leu417Ile) n.617C>A c.45C>A (p.Phe15Leu) c.1339C>A (p.Leu447Ile) c.1288C>A (p.Leu430Ile) c.1174C>A (p.Leu392Ile) c.1279C>A (p.Leu427Ile) c.1129C>A (p.Leu377Ile) c.1021C>A (p.Leu341Ile)	dbSNP
2	g.224503709A>C	CA350827257	CUL3	c.1320T>G (p.Leu440=) c.1122T>G (p.Leu374=) c.1248T>G (p.Leu416=) n.616T>G c.44T>G (p.Phe15Cys) c.1338T>G (p.Leu446=) c.1287T>G (p.Leu429=) c.1173T>G (p.Leu391=) c.1278T>G (p.Leu426=) c.1128T>G (p.Leu376=) c.1020T>G (p.Leu340=)
2	g.224503709A>G	CA350827254	CUL3	c.1320T>C (p.Leu440=) c.1122T>C (p.Leu374=) c.1248T>C (p.Leu416=) n.616T>C c.44T>C (p.Phe15Ser) c.1338T>C (p.Leu446=) c.1287T>C (p.Leu429=) c.1173T>C (p.Leu391=) c.1278T>C (p.Leu426=) c.1128T>C (p.Leu376=) c.1020T>C (p.Leu340=)	gnomAD v4
2	g.224503709A>T	CA350827252	CUL3	c.1320T>A (p.Leu440=) c.1122T>A (p.Leu374=) c.1248T>A (p.Leu416=) n.616T>A c.44T>A (p.Phe15Tyr) c.1338T>A (p.Leu446=) c.1287T>A (p.Leu429=) c.1173T>A (p.Leu391=) c.1278T>A (p.Leu426=) c.1128T>A (p.Leu376=) c.1020T>A (p.Leu340=)
2	g.224503710A>C	CA350827262	CUL3	c.1319T>G (p.Leu440Arg) c.1121T>G (p.Leu374Arg) c.1247T>G (p.Leu416Arg) n.615T>G c.43T>G (p.Phe15Val) c.1337T>G (p.Leu446Arg) c.1286T>G (p.Leu429Arg) c.1172T>G (p.Leu391Arg) c.1277T>G (p.Leu426Arg) c.1127T>G (p.Leu376Arg) c.1019T>G (p.Leu340Arg)
2	g.224503710A>G	CA350827266	CUL3	c.1319T>C (p.Leu440Pro) c.1121T>C (p.Leu374Pro) c.1247T>C (p.Leu416Pro) n.615T>C c.43T>C (p.Phe15Leu) c.1337T>C (p.Leu446Pro) c.1286T>C (p.Leu429Pro) c.1172T>C (p.Leu391Pro) c.1277T>C (p.Leu426Pro) c.1127T>C (p.Leu376Pro) c.1019T>C (p.Leu340Pro)
2	g.224503710A>T	CA350827268	CUL3	c.1319T>A (p.Leu440His) c.1121T>A (p.Leu374His) c.1247T>A (p.Leu416His) n.615T>A c.43T>A (p.Phe15Ile) c.1337T>A (p.Leu446His) c.1286T>A (p.Leu429His) c.1172T>A (p.Leu391His) c.1277T>A (p.Leu426His) c.1127T>A (p.Leu376His) c.1019T>A (p.Leu340His)	dbSNP
2	g.224503711G>A	CA350827270	CUL3	c.1318C>T (p.Leu440Phe) c.1120C>T (p.Leu374Phe) c.1246C>T (p.Leu416Phe) n.614C>T c.42C>T (p.Asp14=) c.1336C>T (p.Leu446Phe) c.1285C>T (p.Leu429Phe) c.1171C>T (p.Leu391Phe) c.1276C>T (p.Leu426Phe) c.1126C>T (p.Leu376Phe) c.1018C>T (p.Leu340Phe)
2	g.224503711G>C	CA350827273	CUL3	c.1318C>G (p.Leu440Val) c.1120C>G (p.Leu374Val) c.1246C>G (p.Leu416Val) n.614C>G c.42C>G (p.Asp14Glu) c.1336C>G (p.Leu446Val) c.1285C>G (p.Leu429Val) c.1171C>G (p.Leu391Val) c.1276C>G (p.Leu426Val) c.1126C>G (p.Leu376Val) c.1018C>G (p.Leu340Val)	dbSNP
2	g.224503711G>T	CA350827276	CUL3	c.1318C>A (p.Leu440Ile) c.1120C>A (p.Leu374Ile) c.1246C>A (p.Leu416Ile) n.614C>A c.42C>A (p.Asp14Glu) c.1336C>A (p.Leu446Ile) c.1285C>A (p.Leu429Ile) c.1171C>A (p.Leu391Ile) c.1276C>A (p.Leu426Ile) c.1126C>A (p.Leu376Ile) c.1018C>A (p.Leu340Ile)
2	g.224503712T>A	CA350827279	CUL3	c.1317A>T (p.Arg439Ser) c.1119A>T (p.Arg373Ser) c.1245A>T (p.Arg415Ser) n.613A>T c.41A>T (p.Asp14Val) c.1335A>T (p.Arg445Ser) c.1284A>T (p.Arg428Ser) c.1170A>T (p.Arg390Ser) c.1275A>T (p.Arg425Ser) c.1125A>T (p.Arg375Ser) c.1017A>T (p.Arg339Ser)	dbSNP
2	g.224503712T>C	CA2140018	CUL3	c.1317A>G (p.Arg439=) c.1119A>G (p.Arg373=) c.1245A>G (p.Arg415=) n.613A>G c.41A>G (p.Asp14Gly) c.1335A>G (p.Arg445=) c.1284A>G (p.Arg428=) c.1170A>G (p.Arg390=) c.1275A>G (p.Arg425=) c.1125A>G (p.Arg375=) c.1017A>G (p.Arg339=)	dbSNP ExAC gnomAD v2 gnomAD v4
2	g.224503712T>G	CA350827282	CUL3	c.1317A>C (p.Arg439Ser) c.1119A>C (p.Arg373Ser) c.1245A>C (p.Arg415Ser) n.613A>C c.41A>C (p.Asp14Ala) c.1335A>C (p.Arg445Ser) c.1284A>C (p.Arg428Ser) c.1170A>C (p.Arg390Ser) c.1275A>C (p.Arg425Ser) c.1125A>C (p.Arg375Ser) c.1017A>C (p.Arg339Ser)	dbSNP
2	g.224503712T=	CA1331555939	CUL3	c.1317A= (p.Arg439=) c.1119A= (p.Arg373=) c.1245A= (p.Arg415=) n.613A= c.41A= (p.Asp14=) c.1335A= (p.Arg445=) c.1284A= (p.Arg428=) c.1170A= (p.Arg390=) c.1275A= (p.Arg425=) c.1125A= (p.Arg375=) c.1017A= (p.Arg339=)
2	g.224503713C>A	CA350827285	CUL3	c.1316G>T (p.Arg439Ile) c.1118G>T (p.Arg373Ile) c.1244G>T (p.Arg415Ile) n.612G>T c.40G>T (p.Asp14Tyr) c.1334G>T (p.Arg445Ile) c.1283G>T (p.Arg428Ile) c.1169G>T (p.Arg390Ile) c.1274G>T (p.Arg425Ile) c.1124G>T (p.Arg375Ile) c.1016G>T (p.Arg339Ile)
2	g.224503713C>G	CA350827286	CUL3	c.1316G>C (p.Arg439Thr) c.1118G>C (p.Arg373Thr) c.1244G>C (p.Arg415Thr) n.612G>C c.40G>C (p.Asp14His) c.1334G>C (p.Arg445Thr) c.1283G>C (p.Arg428Thr) c.1169G>C (p.Arg390Thr) c.1274G>C (p.Arg425Thr) c.1124G>C (p.Arg375Thr) c.1016G>C (p.Arg339Thr)	dbSNP
2	g.224503713C>T	CA350827289	CUL3	c.1316G>A (p.Arg439Lys) c.1118G>A (p.Arg373Lys) c.1244G>A (p.Arg415Lys) n.612G>A c.40G>A (p.Asp14Asn) c.1334G>A (p.Arg445Lys) c.1283G>A (p.Arg428Lys) c.1169G>A (p.Arg390Lys) c.1274G>A (p.Arg425Lys) c.1124G>A (p.Arg375Lys) c.1016G>A (p.Arg339Lys)	dbSNP
2	g.224503715_224503717del	CA645514936	CUL3	c.1314_1316del (p.Arg439del) c.1116_1118del (p.Arg373del) c.1242_1244del (p.Arg415del) n.610_612del c.38_40del (p.Gly13del) c.1332_1334del (p.Arg445del) c.1281_1283del (p.Arg428del) c.1167_1169del (p.Arg390del) c.1272_1274del (p.Arg425del) c.1122_1124del (p.Arg375del) c.1014_1016del (p.Arg339del)	COSMIC
2	g.224503714T>A	CA350827292	CUL3	c.1315A>T (p.Arg439Ter) c.1117A>T (p.Arg373Ter) c.1243A>T (p.Arg415Ter) n.611A>T c.39A>T (p.Gly13=) c.1333A>T (p.Arg445Ter) c.1282A>T (p.Arg428Ter) c.1168A>T (p.Arg390Ter) c.1273A>T (p.Arg425Ter) c.1123A>T (p.Arg375Ter) c.1015A>T (p.Arg339Ter)
2	g.224503714T>C	CA350827295	CUL3	c.1315A>G (p.Arg439Gly) c.1117A>G (p.Arg373Gly) c.1243A>G (p.Arg415Gly) n.611A>G c.39A>G (p.Gly13=) c.1333A>G (p.Arg445Gly) c.1282A>G (p.Arg428Gly) c.1168A>G (p.Arg390Gly) c.1273A>G (p.Arg425Gly) c.1123A>G (p.Arg375Gly) c.1015A>G (p.Arg339Gly)
2	g.224503714T>G	CA431492657	CUL3	c.1315A>C (p.Arg439=) c.1117A>C (p.Arg373=) c.1243A>C (p.Arg415=) n.611A>C c.39A>C (p.Gly13=) c.1333A>C (p.Arg445=) c.1282A>C (p.Arg428=) c.1168A>C (p.Arg390=) c.1273A>C (p.Arg425=) c.1123A>C (p.Arg375=) c.1015A>C (p.Arg339=)
2	g.224503715C>A	CA350827297	CUL3	c.1314G>T (p.Arg438Ser) c.1116G>T (p.Arg372Ser) c.1242G>T (p.Arg414Ser) n.610G>T c.38G>T (p.Gly13Val) c.1332G>T (p.Arg444Ser) c.1281G>T (p.Arg427Ser) c.1167G>T (p.Arg389Ser) c.1272G>T (p.Arg424Ser) c.1122G>T (p.Arg374Ser) c.1014G>T (p.Arg338Ser)
2	g.224503715C>G	CA350827299	CUL3	c.1314G>C (p.Arg438Ser) c.1116G>C (p.Arg372Ser) c.1242G>C (p.Arg414Ser) n.610G>C c.38G>C (p.Gly13Ala) c.1332G>C (p.Arg444Ser) c.1281G>C (p.Arg427Ser) c.1167G>C (p.Arg389Ser) c.1272G>C (p.Arg424Ser) c.1122G>C (p.Arg374Ser) c.1014G>C (p.Arg338Ser)	dbSNP
2	g.224503715C>T	CA350827302	CUL3	c.1314G>A (p.Arg438=) c.1116G>A (p.Arg372=) c.1242G>A (p.Arg414=) n.610G>A c.38G>A (p.Gly13Glu) c.1332G>A (p.Arg444=) c.1281G>A (p.Arg427=) c.1167G>A (p.Arg389=) c.1272G>A (p.Arg424=) c.1122G>A (p.Arg374=) c.1014G>A (p.Arg338=)	dbSNP
2	g.224503716del	CA2577260323	CUL3	c.1314del (p.Arg439AspfsTer16) c.1116del (p.Arg373AspfsTer16) c.1242del (p.Arg415AspfsTer16) n.610del c.38del (p.Gly13GlufsTer6) c.1332del (p.Arg445AspfsTer16) c.1281del (p.Arg428AspfsTer16) c.1167del (p.Arg390AspfsTer16) c.1272del (p.Arg425AspfsTer16) c.1122del (p.Arg375AspfsTer16) c.1014del (p.Arg339AspfsTer16)
2	g.224503716C>A	CA350827306	CUL3	c.1313G>T (p.Arg438Met) c.1115G>T (p.Arg372Met) c.1241G>T (p.Arg414Met) n.609G>T c.37G>T (p.Gly13Ter) c.1331G>T (p.Arg444Met) c.1280G>T (p.Arg427Met) c.1166G>T (p.Arg389Met) c.1271G>T (p.Arg424Met) c.1121G>T (p.Arg374Met) c.1013G>T (p.Arg338Met)	dbSNP gnomAD v4
2	g.224503716C>G	CA350827307	CUL3	c.1313G>C (p.Arg438Thr) c.1115G>C (p.Arg372Thr) c.1241G>C (p.Arg414Thr) n.609G>C c.37G>C (p.Gly13Arg) c.1331G>C (p.Arg444Thr) c.1280G>C (p.Arg427Thr) c.1166G>C (p.Arg389Thr) c.1271G>C (p.Arg424Thr) c.1121G>C (p.Arg374Thr) c.1013G>C (p.Arg338Thr)	dbSNP
2	g.224503716C>T	CA350827308	CUL3	c.1313G>A (p.Arg438Lys) c.1115G>A (p.Arg372Lys) c.1241G>A (p.Arg414Lys) n.609G>A c.37G>A (p.Gly13Arg) c.1331G>A (p.Arg444Lys) c.1280G>A (p.Arg427Lys) c.1166G>A (p.Arg389Lys) c.1271G>A (p.Arg424Lys) c.1121G>A (p.Arg374Lys) c.1013G>A (p.Arg338Lys)	dbSNP
2	g.224503717T>A	CA350827309	CUL3	c.1312A>T (p.Arg438Trp) c.1114A>T (p.Arg372Trp) c.1240A>T (p.Arg414Trp) n.608A>T c.36A>T (p.Gln12His) c.1330A>T (p.Arg444Trp) c.1279A>T (p.Arg427Trp) c.1165A>T (p.Arg389Trp) c.1270A>T (p.Arg424Trp) c.1120A>T (p.Arg374Trp) c.1012A>T (p.Arg338Trp)
2	g.224503717T>C	CA350827311	CUL3	c.1312A>G (p.Arg438Gly) c.1114A>G (p.Arg372Gly) c.1240A>G (p.Arg414Gly) n.608A>G c.36A>G (p.Gln12=) c.1330A>G (p.Arg444Gly) c.1279A>G (p.Arg427Gly) c.1165A>G (p.Arg389Gly) c.1270A>G (p.Arg424Gly) c.1120A>G (p.Arg374Gly) c.1012A>G (p.Arg338Gly)
2	g.224503717T>G	CA350827310	CUL3	c.1312A>C (p.Arg438=) c.1114A>C (p.Arg372=) c.1240A>C (p.Arg414=) n.608A>C c.36A>C (p.Gln12His) c.1330A>C (p.Arg444=) c.1279A>C (p.Arg427=) c.1165A>C (p.Arg389=) c.1270A>C (p.Arg424=) c.1120A>C (p.Arg374=) c.1012A>C (p.Arg338=)
2	g.224503718T>A	CA350827312	CUL3	c.1311A>T (p.Ala437=) c.1113A>T (p.Ala371=) c.1239A>T (p.Ala413=) n.607A>T c.35A>T (p.Gln12Leu) c.1329A>T (p.Ala443=) c.1278A>T (p.Ala426=) c.1164A>T (p.Ala388=) c.1269A>T (p.Ala423=) c.1119A>T (p.Ala373=) c.1011A>T (p.Ala337=)
2	g.224503718T>C	CA350827314	CUL3	c.1311A>G (p.Ala437=) c.1113A>G (p.Ala371=) c.1239A>G (p.Ala413=) n.607A>G c.35A>G (p.Gln12Arg) c.1329A>G (p.Ala443=) c.1278A>G (p.Ala426=) c.1164A>G (p.Ala388=) c.1269A>G (p.Ala423=) c.1119A>G (p.Ala373=) c.1011A>G (p.Ala337=)
2	g.224503718T>G	CA350827313	CUL3	c.1311A>C (p.Ala437=) c.1113A>C (p.Ala371=) c.1239A>C (p.Ala413=) n.607A>C c.35A>C (p.Gln12Pro) c.1329A>C (p.Ala443=) c.1278A>C (p.Ala426=) c.1164A>C (p.Ala388=) c.1269A>C (p.Ala423=) c.1119A>C (p.Ala373=) c.1011A>C (p.Ala337=)
2	g.224503719G>A	CA350827315	CUL3	c.1310C>T (p.Ala437Val) c.1112C>T (p.Ala371Val) c.1238C>T (p.Ala413Val) n.606C>T c.34C>T (p.Gln12Ter) c.1328C>T (p.Ala443Val) c.1277C>T (p.Ala426Val) c.1163C>T (p.Ala388Val) c.1268C>T (p.Ala423Val) c.1118C>T (p.Ala373Val) c.1010C>T (p.Ala337Val)	dbSNP
2	g.224503719G>C	CA350827317	CUL3	c.1310C>G (p.Ala437Gly) c.1112C>G (p.Ala371Gly) c.1238C>G (p.Ala413Gly) n.606C>G c.34C>G (p.Gln12Glu) c.1328C>G (p.Ala443Gly) c.1277C>G (p.Ala426Gly) c.1163C>G (p.Ala388Gly) c.1268C>G (p.Ala423Gly) c.1118C>G (p.Ala373Gly) c.1010C>G (p.Ala337Gly)
2	g.224503719G>T	CA350827318	CUL3	c.1310C>A (p.Ala437Glu) c.1112C>A (p.Ala371Glu) c.1238C>A (p.Ala413Glu) n.606C>A c.34C>A (p.Gln12Lys) c.1328C>A (p.Ala443Glu) c.1277C>A (p.Ala426Glu) c.1163C>A (p.Ala388Glu) c.1268C>A (p.Ala423Glu) c.1118C>A (p.Ala373Glu) c.1010C>A (p.Ala337Glu)
2	g.224503720C>A	CA350827320	CUL3	c.1309G>T (p.Ala437Ser) c.1111G>T (p.Ala371Ser) c.1237G>T (p.Ala413Ser) n.605G>T c.33G>T (p.Trp11Cys) c.1327G>T (p.Ala443Ser) c.1276G>T (p.Ala426Ser) c.1162G>T (p.Ala388Ser) c.1267G>T (p.Ala423Ser) c.1117G>T (p.Ala373Ser) c.1009G>T (p.Ala337Ser)	dbSNP
2	g.224503720C>G	CA350827322	CUL3	c.1309G>C (p.Ala437Pro) c.1111G>C (p.Ala371Pro) c.1237G>C (p.Ala413Pro) n.605G>C c.33G>C (p.Trp11Cys) c.1327G>C (p.Ala443Pro) c.1276G>C (p.Ala426Pro) c.1162G>C (p.Ala388Pro) c.1267G>C (p.Ala423Pro) c.1117G>C (p.Ala373Pro) c.1009G>C (p.Ala337Pro)	dbSNP
2	g.224503720C>T	CA350827323	CUL3	c.1309G>A (p.Ala437Thr) c.1111G>A (p.Ala371Thr) c.1237G>A (p.Ala413Thr) n.605G>A c.33G>A (p.Trp11Ter) c.1327G>A (p.Ala443Thr) c.1276G>A (p.Ala426Thr) c.1162G>A (p.Ala388Thr) c.1267G>A (p.Ala423Thr) c.1117G>A (p.Ala373Thr) c.1009G>A (p.Ala337Thr)	dbSNP
2	g.224503721C>A	CA350827327	CUL3	c.1308G>T (p.Leu436Phe) c.1110G>T (p.Leu370Phe) c.1236G>T (p.Leu412Phe) n.604G>T c.32G>T (p.Trp11Leu) c.1326G>T (p.Leu442Phe) c.1275G>T (p.Leu425Phe) c.1161G>T (p.Leu387Phe) c.1266G>T (p.Leu422Phe) c.1116G>T (p.Leu372Phe) c.1008G>T (p.Leu336Phe)	dbSNP gnomAD v4
2	g.224503721C>G	CA350827329	CUL3	c.1308G>C (p.Leu436Phe) c.1110G>C (p.Leu370Phe) c.1236G>C (p.Leu412Phe) n.604G>C c.32G>C (p.Trp11Ser) c.1326G>C (p.Leu442Phe) c.1275G>C (p.Leu425Phe) c.1161G>C (p.Leu387Phe) c.1266G>C (p.Leu422Phe) c.1116G>C (p.Leu372Phe) c.1008G>C (p.Leu336Phe)	dbSNP
2	g.224503721C>T	CA350827332	CUL3	c.1308G>A (p.Leu436=) c.1110G>A (p.Leu370=) c.1236G>A (p.Leu412=) n.604G>A c.32G>A (p.Trp11Ter) c.1326G>A (p.Leu442=) c.1275G>A (p.Leu425=) c.1161G>A (p.Leu387=) c.1266G>A (p.Leu422=) c.1116G>A (p.Leu372=) c.1008G>A (p.Leu336=)	dbSNP
2	g.224503722A>C	CA350827334	CUL3	c.1307T>G (p.Leu436Trp) c.1109T>G (p.Leu370Trp) c.1235T>G (p.Leu412Trp) n.603T>G c.31T>G (p.Trp11Gly) c.1325T>G (p.Leu442Trp) c.1274T>G (p.Leu425Trp) c.1160T>G (p.Leu387Trp) c.1265T>G (p.Leu422Trp) c.1115T>G (p.Leu372Trp) c.1007T>G (p.Leu336Trp)
2	g.224503722A>G	CA350827337	CUL3	c.1307T>C (p.Leu436Ser) c.1109T>C (p.Leu370Ser) c.1235T>C (p.Leu412Ser) n.603T>C c.31T>C (p.Trp11Arg) c.1325T>C (p.Leu442Ser) c.1274T>C (p.Leu425Ser) c.1160T>C (p.Leu387Ser) c.1265T>C (p.Leu422Ser) c.1115T>C (p.Leu372Ser) c.1007T>C (p.Leu336Ser)	dbSNP
2	g.224503722A>T	CA350827341	CUL3	c.1307T>A (p.Leu436Ter) c.1109T>A (p.Leu370Ter) c.1235T>A (p.Leu412Ter) n.603T>A c.31T>A (p.Trp11Arg) c.1325T>A (p.Leu442Ter) c.1274T>A (p.Leu425Ter) c.1160T>A (p.Leu387Ter) c.1265T>A (p.Leu422Ter) c.1115T>A (p.Leu372Ter) c.1007T>A (p.Leu336Ter)	dbSNP
2	g.224503723A>C	CA350827345	CUL3	c.1306T>G (p.Leu436Val) c.1108T>G (p.Leu370Val) c.1234T>G (p.Leu412Val) n.602T>G c.30T>G (p.Thr10=) c.1324T>G (p.Leu442Val) c.1273T>G (p.Leu425Val) c.1159T>G (p.Leu387Val) c.1264T>G (p.Leu422Val) c.1114T>G (p.Leu372Val) c.1006T>G (p.Leu336Val)	ClinVar gnomAD v4
2	g.224503723A>G	CA431492669	CUL3	c.1306T>C (p.Leu436=) c.1108T>C (p.Leu370=) c.1234T>C (p.Leu412=) n.602T>C c.30T>C (p.Thr10=) c.1324T>C (p.Leu442=) c.1273T>C (p.Leu425=) c.1159T>C (p.Leu387=) c.1264T>C (p.Leu422=) c.1114T>C (p.Leu372=) c.1006T>C (p.Leu336=)	gnomAD v4
2	g.224503723A>T	CA350827348	CUL3	c.1306T>A (p.Leu436Met) c.1108T>A (p.Leu370Met) c.1234T>A (p.Leu412Met) n.602T>A c.30T>A (p.Thr10=) c.1324T>A (p.Leu442Met) c.1273T>A (p.Leu425Met) c.1159T>A (p.Leu387Met) c.1264T>A (p.Leu422Met) c.1114T>A (p.Leu372Met) c.1006T>A (p.Leu336Met)	dbSNP
2	g.224503724G>A	CA350827351	CUL3	c.1305C>T (p.His435=) c.1107C>T (p.His369=) c.1233C>T (p.His411=) n.601C>T c.29C>T (p.Thr10Ile) c.1323C>T (p.His441=) c.1272C>T (p.His424=) c.1158C>T (p.His386=) c.1263C>T (p.His421=) c.1113C>T (p.His371=) c.1005C>T (p.His335=)	dbSNP gnomAD v3 gnomAD v4
2	g.224503724G>C	CA350827354	CUL3	c.1305C>G (p.His435Gln) c.1107C>G (p.His369Gln) c.1233C>G (p.His411Gln) n.601C>G c.29C>G (p.Thr10Ser) c.1323C>G (p.His441Gln) c.1272C>G (p.His424Gln) c.1158C>G (p.His386Gln) c.1263C>G (p.His421Gln) c.1113C>G (p.His371Gln) c.1005C>G (p.His335Gln)	dbSNP
2	g.224503724G=	CA1331555940	CUL3	c.1305C= (p.His435=) c.1107C= (p.His369=) c.1233C= (p.His411=) n.601C= c.29C= (p.Thr10=) c.1323C= (p.His441=) c.1272C= (p.His424=) c.1158C= (p.His386=) c.1263C= (p.His421=) c.1113C= (p.His371=) c.1005C= (p.His335=)
2	g.224503724G>T	CA350827357	CUL3	c.1305C>A (p.His435Gln) c.1107C>A (p.His369Gln) c.1233C>A (p.His411Gln) n.601C>A c.29C>A (p.Thr10Asn) c.1323C>A (p.His441Gln) c.1272C>A (p.His424Gln) c.1158C>A (p.His386Gln) c.1263C>A (p.His421Gln) c.1113C>A (p.His371Gln) c.1005C>A (p.His335Gln)
2	g.224503725T>A	CA350827361	CUL3	c.1304A>T (p.His435Leu) c.1106A>T (p.His369Leu) c.1232A>T (p.His411Leu) n.600A>T c.28A>T (p.Thr10Ser) c.1322A>T (p.His441Leu) c.1271A>T (p.His424Leu) c.1157A>T (p.His386Leu) c.1262A>T (p.His421Leu) c.1112A>T (p.His371Leu) c.1004A>T (p.His335Leu)	dbSNP
2	g.224503725T>C	CA350827364	CUL3	c.1304A>G (p.His435Arg) c.1106A>G (p.His369Arg) c.1232A>G (p.His411Arg) n.600A>G c.28A>G (p.Thr10Ala) c.1322A>G (p.His441Arg) c.1271A>G (p.His424Arg) c.1157A>G (p.His386Arg) c.1262A>G (p.His421Arg) c.1112A>G (p.His371Arg) c.1004A>G (p.His335Arg)
2	g.224503725T>G	CA350827366	CUL3	c.1304A>C (p.His435Pro) c.1106A>C (p.His369Pro) c.1232A>C (p.His411Pro) n.600A>C c.28A>C (p.Thr10Pro) c.1322A>C (p.His441Pro) c.1271A>C (p.His424Pro) c.1157A>C (p.His386Pro) c.1262A>C (p.His421Pro) c.1112A>C (p.His371Pro) c.1004A>C (p.His335Pro)	dbSNP
2	g.224503726G>A	CA350827370	CUL3	c.1303C>T (p.His435Tyr) c.1105C>T (p.His369Tyr) c.1231C>T (p.His411Tyr) n.599C>T c.27C>T (p.Asn9=) c.1321C>T (p.His441Tyr) c.1270C>T (p.His424Tyr) c.1156C>T (p.His386Tyr) c.1261C>T (p.His421Tyr) c.1111C>T (p.His371Tyr) c.1003C>T (p.His335Tyr)	dbSNP
2	g.224503726G>C	CA350827373	CUL3	c.1303C>G (p.His435Asp) c.1105C>G (p.His369Asp) c.1231C>G (p.His411Asp) n.599C>G c.27C>G (p.Asn9Lys) c.1321C>G (p.His441Asp) c.1270C>G (p.His424Asp) c.1156C>G (p.His386Asp) c.1261C>G (p.His421Asp) c.1111C>G (p.His371Asp) c.1003C>G (p.His335Asp)	dbSNP
2	g.224503726G>T	CA350827375	CUL3	c.1303C>A (p.His435Asn) c.1105C>A (p.His369Asn) c.1231C>A (p.His411Asn) n.599C>A c.27C>A (p.Asn9Lys) c.1321C>A (p.His441Asn) c.1270C>A (p.His424Asn) c.1156C>A (p.His386Asn) c.1261C>A (p.His421Asn) c.1111C>A (p.His371Asn) c.1003C>A (p.His335Asn)
2	g.224503727T>A	CA350827378	CUL3	c.1302A>T (p.Gln434His) c.1104A>T (p.Gln368His) c.1230A>T (p.Gln410His) n.598A>T c.26A>T (p.Asn9Ile) c.1320A>T (p.Gln440His) c.1269A>T (p.Gln423His) c.1155A>T (p.Gln385His) c.1260A>T (p.Gln420His) c.1110A>T (p.Gln370His) c.1002A>T (p.Gln334His)	dbSNP
2	g.224503727T>C	CA66534322	CUL3	c.1302A>G (p.Gln434=) c.1104A>G (p.Gln368=) c.1230A>G (p.Gln410=) n.598A>G c.26A>G (p.Asn9Ser) c.1320A>G (p.Gln440=) c.1269A>G (p.Gln423=) c.1155A>G (p.Gln385=) c.1260A>G (p.Gln420=) c.1110A>G (p.Gln370=) c.1002A>G (p.Gln334=)	dbSNP
2	g.224503727T>G	CA350827382	CUL3	c.1302A>C (p.Gln434His) c.1104A>C (p.Gln368His) c.1230A>C (p.Gln410His) n.598A>C c.26A>C (p.Asn9Thr) c.1320A>C (p.Gln440His) c.1269A>C (p.Gln423His) c.1155A>C (p.Gln385His) c.1260A>C (p.Gln420His) c.1110A>C (p.Gln370His) c.1002A>C (p.Gln334His)
2	g.224503727T=	CA1331555941	CUL3	c.1302A= (p.Gln434=) c.1104A= (p.Gln368=) c.1230A= (p.Gln410=) n.598A= c.26A= (p.Asn9=) c.1320A= (p.Gln440=) c.1269A= (p.Gln423=) c.1155A= (p.Gln385=) c.1260A= (p.Gln420=) c.1110A= (p.Gln370=) c.1002A= (p.Gln334=)
2	g.224503728T>A	CA350827386	CUL3	c.1301A>T (p.Gln434Leu) c.1103A>T (p.Gln368Leu) c.1229A>T (p.Gln410Leu) n.597A>T c.25A>T (p.Asn9Tyr) c.1319A>T (p.Gln440Leu) c.1268A>T (p.Gln423Leu) c.1154A>T (p.Gln385Leu) c.1259A>T (p.Gln420Leu) c.1109A>T (p.Gln370Leu) c.1001A>T (p.Gln334Leu)	dbSNP
2	g.224503728T>C	CA350827391	CUL3	c.1301A>G (p.Gln434Arg) c.1103A>G (p.Gln368Arg) c.1229A>G (p.Gln410Arg) n.597A>G c.25A>G (p.Asn9Asp) c.1319A>G (p.Gln440Arg) c.1268A>G (p.Gln423Arg) c.1154A>G (p.Gln385Arg) c.1259A>G (p.Gln420Arg) c.1109A>G (p.Gln370Arg) c.1001A>G (p.Gln334Arg)
2	g.224503728T>G	CA350827388	CUL3	c.1301A>C (p.Gln434Pro) c.1103A>C (p.Gln368Pro) c.1229A>C (p.Gln410Pro) n.597A>C c.25A>C (p.Asn9His) c.1319A>C (p.Gln440Pro) c.1268A>C (p.Gln423Pro) c.1154A>C (p.Gln385Pro) c.1259A>C (p.Gln420Pro) c.1109A>C (p.Gln370Pro) c.1001A>C (p.Gln334Pro)
2	g.224503729G>A	CA350827395	CUL3	c.1300C>T (p.Gln434Ter) c.1102C>T (p.Gln368Ter) c.1228C>T (p.Gln410Ter) n.596C>T c.24C>T (p.Asn8=) c.1318C>T (p.Gln440Ter) c.1267C>T (p.Gln423Ter) c.1153C>T (p.Gln385Ter) c.1258C>T (p.Gln420Ter) c.1108C>T (p.Gln370Ter) c.1000C>T (p.Gln334Ter)
2	g.224503729G>C	CA350827397	CUL3	c.1300C>G (p.Gln434Glu) c.1102C>G (p.Gln368Glu) c.1228C>G (p.Gln410Glu) n.596C>G c.24C>G (p.Asn8Lys) c.1318C>G (p.Gln440Glu) c.1267C>G (p.Gln423Glu) c.1153C>G (p.Gln385Glu) c.1258C>G (p.Gln420Glu) c.1108C>G (p.Gln370Glu) c.1000C>G (p.Gln334Glu)
2	g.224503729G>T	CA350827400	CUL3	c.1300C>A (p.Gln434Lys) c.1102C>A (p.Gln368Lys) c.1228C>A (p.Gln410Lys) n.596C>A c.24C>A (p.Asn8Lys) c.1318C>A (p.Gln440Lys) c.1267C>A (p.Gln423Lys) c.1153C>A (p.Gln385Lys) c.1258C>A (p.Gln420Lys) c.1108C>A (p.Gln370Lys) c.1000C>A (p.Gln334Lys)
2	g.224503730T>A	CA350827402	CUL3	c.1299A>T (p.Lys433Asn) c.1101A>T (p.Lys367Asn) c.1227A>T (p.Lys409Asn) n.595A>T c.23A>T (p.Asn8Ile) c.1317A>T (p.Lys439Asn) c.1266A>T (p.Lys422Asn) c.1152A>T (p.Lys384Asn) c.1257A>T (p.Lys419Asn) c.1107A>T (p.Lys369Asn) c.999A>T (p.Lys333Asn)	dbSNP
2	g.224503730T>C	CA350827404	CUL3	c.1299A>G (p.Lys433=) c.1101A>G (p.Lys367=) c.1227A>G (p.Lys409=) n.595A>G c.23A>G (p.Asn8Ser) c.1317A>G (p.Lys439=) c.1266A>G (p.Lys422=) c.1152A>G (p.Lys384=) c.1257A>G (p.Lys419=) c.1107A>G (p.Lys369=) c.999A>G (p.Lys333=)	gnomAD v4
2	g.224503730T>G	CA350827405	CUL3	c.1299A>C (p.Lys433Asn) c.1101A>C (p.Lys367Asn) c.1227A>C (p.Lys409Asn) n.595A>C c.23A>C (p.Asn8Thr) c.1317A>C (p.Lys439Asn) c.1266A>C (p.Lys422Asn) c.1152A>C (p.Lys384Asn) c.1257A>C (p.Lys419Asn) c.1107A>C (p.Lys369Asn) c.999A>C (p.Lys333Asn)	dbSNP
2	g.224503731T>A	CA350827409	CUL3	c.1298A>T (p.Lys433Ile) c.1100A>T (p.Lys367Ile) c.1226A>T (p.Lys409Ile) n.594A>T c.22A>T (p.Asn8Tyr) c.1316A>T (p.Lys439Ile) c.1265A>T (p.Lys422Ile) c.1151A>T (p.Lys384Ile) c.1256A>T (p.Lys419Ile) c.1106A>T (p.Lys369Ile) c.998A>T (p.Lys333Ile)	dbSNP
2	g.224503731T>C	CA350827410	CUL3	c.1298A>G (p.Lys433Arg) c.1100A>G (p.Lys367Arg) c.1226A>G (p.Lys409Arg) n.594A>G c.22A>G (p.Asn8Asp) c.1316A>G (p.Lys439Arg) c.1265A>G (p.Lys422Arg) c.1151A>G (p.Lys384Arg) c.1256A>G (p.Lys419Arg) c.1106A>G (p.Lys369Arg) c.998A>G (p.Lys333Arg)
2	g.224503731T>G	CA350827411	CUL3	c.1298A>C (p.Lys433Thr) c.1100A>C (p.Lys367Thr) c.1226A>C (p.Lys409Thr) n.594A>C c.22A>C (p.Asn8His) c.1316A>C (p.Lys439Thr) c.1265A>C (p.Lys422Thr) c.1151A>C (p.Lys384Thr) c.1256A>C (p.Lys419Thr) c.1106A>C (p.Lys369Thr) c.998A>C (p.Lys333Thr)	dbSNP
2	g.224503732T>A	CA350827412	CUL3	c.1297A>T (p.Lys433Ter) c.1099A>T (p.Lys367Ter) c.1225A>T (p.Lys409Ter) n.593A>T c.21A>T (p.Ile7=) c.1315A>T (p.Lys439Ter) c.1264A>T (p.Lys422Ter) c.1150A>T (p.Lys384Ter) c.1255A>T (p.Lys419Ter) c.1105A>T (p.Lys369Ter) c.997A>T (p.Lys333Ter)	dbSNP
2	g.224503732T>C	CA350827413	CUL3	c.1297A>G (p.Lys433Glu) c.1099A>G (p.Lys367Glu) c.1225A>G (p.Lys409Glu) n.593A>G c.21A>G (p.Ile7Met) c.1315A>G (p.Lys439Glu) c.1264A>G (p.Lys422Glu) c.1150A>G (p.Lys384Glu) c.1255A>G (p.Lys419Glu) c.1105A>G (p.Lys369Glu) c.997A>G (p.Lys333Glu)
2	g.224503732T>G	CA350827415	CUL3	c.1297A>C (p.Lys433Gln) c.1099A>C (p.Lys367Gln) c.1225A>C (p.Lys409Gln) n.593A>C c.21A>C (p.Ile7=) c.1315A>C (p.Lys439Gln) c.1264A>C (p.Lys422Gln) c.1150A>C (p.Lys384Gln) c.1255A>C (p.Lys419Gln) c.1105A>C (p.Lys369Gln) c.997A>C (p.Lys333Gln)
2	g.224503733A>C	CA350827420	CUL3	c.1296T>G (p.Tyr432Ter) c.1098T>G (p.Tyr366Ter) c.1224T>G (p.Tyr408Ter) n.592T>G c.20T>G (p.Ile7Arg) c.1314T>G (p.Tyr438Ter) c.1263T>G (p.Tyr421Ter) c.1149T>G (p.Tyr383Ter) c.1254T>G (p.Tyr418Ter) c.1104T>G (p.Tyr368Ter) c.996T>G (p.Tyr332Ter)
2	g.224503733A>G	CA350827417	CUL3	c.1296T>C (p.Tyr432=) c.1098T>C (p.Tyr366=) c.1224T>C (p.Tyr408=) n.592T>C c.20T>C (p.Ile7Thr) c.1314T>C (p.Tyr438=) c.1263T>C (p.Tyr421=) c.1149T>C (p.Tyr383=) c.1254T>C (p.Tyr418=) c.1104T>C (p.Tyr368=) c.996T>C (p.Tyr332=)
2	g.224503733A>T	CA350827418	CUL3	c.1296T>A (p.Tyr432Ter) c.1098T>A (p.Tyr366Ter) c.1224T>A (p.Tyr408Ter) n.592T>A c.20T>A (p.Ile7Lys) c.1314T>A (p.Tyr438Ter) c.1263T>A (p.Tyr421Ter) c.1149T>A (p.Tyr383Ter) c.1254T>A (p.Tyr418Ter) c.1104T>A (p.Tyr368Ter) c.996T>A (p.Tyr332Ter)	dbSNP
2	g.224503734T>A	CA350827421	CUL3	c.1295A>T (p.Tyr432Phe) c.1097A>T (p.Tyr366Phe) c.1223A>T (p.Tyr408Phe) n.591A>T c.19A>T (p.Ile7Leu) c.1313A>T (p.Tyr438Phe) c.1262A>T (p.Tyr421Phe) c.1148A>T (p.Tyr383Phe) c.1253A>T (p.Tyr418Phe) c.1103A>T (p.Tyr368Phe) c.995A>T (p.Tyr332Phe)
2	g.224503734T>C	CA350827423	CUL3	c.1295A>G (p.Tyr432Cys) c.1097A>G (p.Tyr366Cys) c.1223A>G (p.Tyr408Cys) n.591A>G c.19A>G (p.Ile7Val) c.1313A>G (p.Tyr438Cys) c.1262A>G (p.Tyr421Cys) c.1148A>G (p.Tyr383Cys) c.1253A>G (p.Tyr418Cys) c.1103A>G (p.Tyr368Cys) c.995A>G (p.Tyr332Cys)
2	g.224503734T>G	CA350827425	CUL3	c.1295A>C (p.Tyr432Ser) c.1097A>C (p.Tyr366Ser) c.1223A>C (p.Tyr408Ser) n.591A>C c.19A>C (p.Ile7Leu) c.1313A>C (p.Tyr438Ser) c.1262A>C (p.Tyr421Ser) c.1148A>C (p.Tyr383Ser) c.1253A>C (p.Tyr418Ser) c.1103A>C (p.Tyr368Ser) c.995A>C (p.Tyr332Ser)
2	g.224503735A>C	CA350827427	CUL3	c.1294T>G (p.Tyr432Asp) c.1096T>G (p.Tyr366Asp) c.1222T>G (p.Tyr408Asp) n.590T>G c.18T>G (p.Ile6Met) c.1312T>G (p.Tyr438Asp) c.1261T>G (p.Tyr421Asp) c.1147T>G (p.Tyr383Asp) c.1252T>G (p.Tyr418Asp) c.1102T>G (p.Tyr368Asp) c.994T>G (p.Tyr332Asp)	ClinVar dbSNP
2	g.224503735A>G	CA350827428	CUL3	c.1294T>C (p.Tyr432His) c.1096T>C (p.Tyr366His) c.1222T>C (p.Tyr408His) n.590T>C c.18T>C (p.Ile6=) c.1312T>C (p.Tyr438His) c.1261T>C (p.Tyr421His) c.1147T>C (p.Tyr383His) c.1252T>C (p.Tyr418His) c.1102T>C (p.Tyr368His) c.994T>C (p.Tyr332His)
2	g.224503735A>T	CA350827431	CUL3	c.1294T>A (p.Tyr432Asn) c.1096T>A (p.Tyr366Asn) c.1222T>A (p.Tyr408Asn) n.590T>A c.18T>A (p.Ile6=) c.1312T>A (p.Tyr438Asn) c.1261T>A (p.Tyr421Asn) c.1147T>A (p.Tyr383Asn) c.1252T>A (p.Tyr418Asn) c.1102T>A (p.Tyr368Asn) c.994T>A (p.Tyr332Asn)	dbSNP
2	g.224503736del	CA2701738708	CUL3	c.1294del (p.Tyr432IlefsTer23) c.1096del (p.Tyr366IlefsTer23) c.1222del (p.Tyr408IlefsTer23) n.590del c.18del (p.Ile7Ter) c.1312del (p.Tyr438IlefsTer23) c.1261del (p.Tyr421IlefsTer23) c.1147del (p.Tyr383IlefsTer23) c.1252del (p.Tyr418IlefsTer23) c.1102del (p.Tyr368IlefsTer23) c.994del (p.Tyr332IlefsTer23)	dbSNP
2	g.224503736A=	CA1331555942	CUL3	c.1293T= (p.Tyr431=) c.1095T= (p.Tyr365=) c.1221T= (p.Tyr407=) n.589T= c.17T= (p.Ile6=) c.1311T= (p.Tyr437=) c.1260T= (p.Tyr420=) c.1146T= (p.Tyr382=) c.1251T= (p.Tyr417=) c.1101T= (p.Tyr367=) c.993T= (p.Tyr331=)
2	g.224503736A>C	CA350827433	CUL3	c.1293T>G (p.Tyr431Ter) c.1095T>G (p.Tyr365Ter) c.1221T>G (p.Tyr407Ter) n.589T>G c.17T>G (p.Ile6Ser) c.1311T>G (p.Tyr437Ter) c.1260T>G (p.Tyr420Ter) c.1146T>G (p.Tyr382Ter) c.1251T>G (p.Tyr417Ter) c.1101T>G (p.Tyr367Ter) c.993T>G (p.Tyr331Ter)
2	g.224503736A>G	CA2140019	CUL3	c.1293T>C (p.Tyr431=) c.1095T>C (p.Tyr365=) c.1221T>C (p.Tyr407=) n.589T>C c.17T>C (p.Ile6Thr) c.1311T>C (p.Tyr437=) c.1260T>C (p.Tyr420=) c.1146T>C (p.Tyr382=) c.1251T>C (p.Tyr417=) c.1101T>C (p.Tyr367=) c.993T>C (p.Tyr331=)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
2	g.224503736A>T	CA350827435	CUL3	c.1293T>A (p.Tyr431Ter) c.1095T>A (p.Tyr365Ter) c.1221T>A (p.Tyr407Ter) n.589T>A c.17T>A (p.Ile6Asn) c.1311T>A (p.Tyr437Ter) c.1260T>A (p.Tyr420Ter) c.1146T>A (p.Tyr382Ter) c.1251T>A (p.Tyr417Ter) c.1101T>A (p.Tyr367Ter) c.993T>A (p.Tyr331Ter)	dbSNP
2	g.224503737T>A	CA350827437	CUL3	c.1292A>T (p.Tyr431Phe) c.1094A>T (p.Tyr365Phe) c.1220A>T (p.Tyr407Phe) n.588A>T c.16A>T (p.Ile6Phe) c.1310A>T (p.Tyr437Phe) c.1259A>T (p.Tyr420Phe) c.1145A>T (p.Tyr382Phe) c.1250A>T (p.Tyr417Phe) c.1100A>T (p.Tyr367Phe) c.992A>T (p.Tyr331Phe)	dbSNP
2	g.224503737T>C	CA350827439	CUL3	c.1292A>G (p.Tyr431Cys) c.1094A>G (p.Tyr365Cys) c.1220A>G (p.Tyr407Cys) n.588A>G c.16A>G (p.Ile6Val) c.1310A>G (p.Tyr437Cys) c.1259A>G (p.Tyr420Cys) c.1145A>G (p.Tyr382Cys) c.1250A>G (p.Tyr417Cys) c.1100A>G (p.Tyr367Cys) c.992A>G (p.Tyr331Cys)
2	g.224503737T>G	CA350827441	CUL3	c.1292A>C (p.Tyr431Ser) c.1094A>C (p.Tyr365Ser) c.1220A>C (p.Tyr407Ser) n.588A>C c.16A>C (p.Ile6Leu) c.1310A>C (p.Tyr437Ser) c.1259A>C (p.Tyr420Ser) c.1145A>C (p.Tyr382Ser) c.1250A>C (p.Tyr417Ser) c.1100A>C (p.Tyr367Ser) c.992A>C (p.Tyr331Ser)
2	g.224503738A>C	CA350827446	CUL3	c.1291T>G (p.Tyr431Asp) c.1093T>G (p.Tyr365Asp) c.1219T>G (p.Tyr407Asp) n.587T>G c.15T>G (p.Val5=) c.1309T>G (p.Tyr437Asp) c.1258T>G (p.Tyr420Asp) c.1144T>G (p.Tyr382Asp) c.1249T>G (p.Tyr417Asp) c.1099T>G (p.Tyr367Asp) c.991T>G (p.Tyr331Asp)
2	g.224503738A>G	CA350827447	CUL3	c.1291T>C (p.Tyr431His) c.1093T>C (p.Tyr365His) c.1219T>C (p.Tyr407His) n.587T>C c.15T>C (p.Val5=) c.1309T>C (p.Tyr437His) c.1258T>C (p.Tyr420His) c.1144T>C (p.Tyr382His) c.1249T>C (p.Tyr417His) c.1099T>C (p.Tyr367His) c.991T>C (p.Tyr331His)
2	g.224503738A>T	CA350827444	CUL3	c.1291T>A (p.Tyr431Asn) c.1093T>A (p.Tyr365Asn) c.1219T>A (p.Tyr407Asn) n.587T>A c.15T>A (p.Val5=) c.1309T>A (p.Tyr437Asn) c.1258T>A (p.Tyr420Asn) c.1144T>A (p.Tyr382Asn) c.1249T>A (p.Tyr417Asn) c.1099T>A (p.Tyr367Asn) c.991T>A (p.Tyr331Asn)	dbSNP
2	g.224503739A=	CA1331555943	CUL3	c.1290T= (p.Arg430=) c.1092T= (p.Arg364=) c.1218T= (p.Arg406=) n.586T= c.14T= (p.Val5=) c.1308T= (p.Arg436=) c.1257T= (p.Arg419=) c.1143T= (p.Arg381=) c.1248T= (p.Arg416=) c.1098T= (p.Arg366=) c.990T= (p.Arg330=)
2	g.224503739A>C	CA350827449	CUL3	c.1290T>G (p.Arg430=) c.1092T>G (p.Arg364=) c.1218T>G (p.Arg406=) n.586T>G c.14T>G (p.Val5Gly) c.1308T>G (p.Arg436=) c.1257T>G (p.Arg419=) c.1143T>G (p.Arg381=) c.1248T>G (p.Arg416=) c.1098T>G (p.Arg366=) c.990T>G (p.Arg330=)	dbSNP gnomAD v2
2	g.224503739A>G	CA350827452	CUL3	c.1290T>C (p.Arg430=) c.1092T>C (p.Arg364=) c.1218T>C (p.Arg406=) n.586T>C c.14T>C (p.Val5Ala) c.1308T>C (p.Arg436=) c.1257T>C (p.Arg419=) c.1143T>C (p.Arg381=) c.1248T>C (p.Arg416=) c.1098T>C (p.Arg366=) c.990T>C (p.Arg330=)	dbSNP gnomAD v2 gnomAD v4
2	g.224503739A>T	CA350827450	CUL3	c.1290T>A (p.Arg430=) c.1092T>A (p.Arg364=) c.1218T>A (p.Arg406=) n.586T>A c.14T>A (p.Val5Asp) c.1308T>A (p.Arg436=) c.1257T>A (p.Arg419=) c.1143T>A (p.Arg381=) c.1248T>A (p.Arg416=) c.1098T>A (p.Arg366=) c.990T>A (p.Arg330=)	dbSNP
2	g.224503740C>A	CA350827454	CUL3	c.1289G>T (p.Arg430Leu) c.1091G>T (p.Arg364Leu) c.1217G>T (p.Arg406Leu) n.585G>T c.13G>T (p.Val5Phe) c.1307G>T (p.Arg436Leu) c.1256G>T (p.Arg419Leu) c.1142G>T (p.Arg381Leu) c.1247G>T (p.Arg416Leu) c.1097G>T (p.Arg366Leu) c.989G>T (p.Arg330Leu)	dbSNP
2	g.224503740C>G	CA350827456	CUL3	c.1289G>C (p.Arg430Pro) c.1091G>C (p.Arg364Pro) c.1217G>C (p.Arg406Pro) n.585G>C c.13G>C (p.Val5Leu) c.1307G>C (p.Arg436Pro) c.1256G>C (p.Arg419Pro) c.1142G>C (p.Arg381Pro) c.1247G>C (p.Arg416Pro) c.1097G>C (p.Arg366Pro) c.989G>C (p.Arg330Pro)	dbSNP
2	g.224503740C>T	CA350827457	CUL3	c.1289G>A (p.Arg430His) c.1091G>A (p.Arg364His) c.1217G>A (p.Arg406His) n.585G>A c.13G>A (p.Val5Ile) c.1307G>A (p.Arg436His) c.1256G>A (p.Arg419His) c.1142G>A (p.Arg381His) c.1247G>A (p.Arg416His) c.1097G>A (p.Arg366His) c.989G>A (p.Arg330His)	ClinVar dbSNP gnomAD v4
2	g.224503741G>A	CA350827459	CUL3	c.1288C>T (p.Arg430Cys) c.1090C>T (p.Arg364Cys) c.1216C>T (p.Arg406Cys) n.584C>T c.12C>T (p.Asn4=) c.1306C>T (p.Arg436Cys) c.1255C>T (p.Arg419Cys) c.1141C>T (p.Arg381Cys) c.1246C>T (p.Arg416Cys) c.1096C>T (p.Arg366Cys) c.988C>T (p.Arg330Cys)	dbSNP gnomAD v2 COSMIC
2	g.224503741G>C	CA350827461	CUL3	c.1288C>G (p.Arg430Gly) c.1090C>G (p.Arg364Gly) c.1216C>G (p.Arg406Gly) n.584C>G c.12C>G (p.Asn4Lys) c.1306C>G (p.Arg436Gly) c.1255C>G (p.Arg419Gly) c.1141C>G (p.Arg381Gly) c.1246C>G (p.Arg416Gly) c.1096C>G (p.Arg366Gly) c.988C>G (p.Arg330Gly)	dbSNP
2	g.224503741G=	CA1331555944	CUL3	c.1288C= (p.Arg430=) c.1090C= (p.Arg364=) c.1216C= (p.Arg406=) n.584C= c.12C= (p.Asn4=) c.1306C= (p.Arg436=) c.1255C= (p.Arg419=) c.1141C= (p.Arg381=) c.1246C= (p.Arg416=) c.1096C= (p.Arg366=) c.988C= (p.Arg330=)
2	g.224503741G>T	CA350827463	CUL3	c.1288C>A (p.Arg430Ser) c.1090C>A (p.Arg364Ser) c.1216C>A (p.Arg406Ser) n.584C>A c.12C>A (p.Asn4Lys) c.1306C>A (p.Arg436Ser) c.1255C>A (p.Arg419Ser) c.1141C>A (p.Arg381Ser) c.1246C>A (p.Arg416Ser) c.1096C>A (p.Arg366Ser) c.988C>A (p.Arg330Ser)	dbSNP gnomAD v4
2	g.224503742T>A	CA350827469	CUL3	c.1287A>T (p.Glu429Asp) c.1089A>T (p.Glu363Asp) c.1215A>T (p.Glu405Asp) n.583A>T c.11A>T (p.Asn4Ile) c.1305A>T (p.Glu435Asp) c.1254A>T (p.Glu418Asp) c.1140A>T (p.Glu380Asp) c.1245A>T (p.Glu415Asp) c.1095A>T (p.Glu365Asp) c.987A>T (p.Glu329Asp)	dbSNP
2	g.224503742T>C	CA350827467	CUL3	c.1287A>G (p.Glu429=) c.1089A>G (p.Glu363=) c.1215A>G (p.Glu405=) n.583A>G c.11A>G (p.Asn4Ser) c.1305A>G (p.Glu435=) c.1254A>G (p.Glu418=) c.1140A>G (p.Glu380=) c.1245A>G (p.Glu415=) c.1095A>G (p.Glu365=) c.987A>G (p.Glu329=)
2	g.224503742T>G	CA350827465	CUL3	c.1287A>C (p.Glu429Asp) c.1089A>C (p.Glu363Asp) c.1215A>C (p.Glu405Asp) n.583A>C c.11A>C (p.Asn4Thr) c.1305A>C (p.Glu435Asp) c.1254A>C (p.Glu418Asp) c.1140A>C (p.Glu380Asp) c.1245A>C (p.Glu415Asp) c.1095A>C (p.Glu365Asp) c.987A>C (p.Glu329Asp)
2	g.224503743T>A	CA350827471	CUL3	c.1286A>T (p.Glu429Val) c.1088A>T (p.Glu363Val) c.1214A>T (p.Glu405Val) n.582A>T c.10A>T (p.Asn4Tyr) c.1304A>T (p.Glu435Val) c.1253A>T (p.Glu418Val) c.1139A>T (p.Glu380Val) c.1244A>T (p.Glu415Val) c.1094A>T (p.Glu365Val) c.986A>T (p.Glu329Val)	dbSNP
2	g.224503743T>C	CA350827473	CUL3	c.1286A>G (p.Glu429Gly) c.1088A>G (p.Glu363Gly) c.1214A>G (p.Glu405Gly) n.582A>G c.10A>G (p.Asn4Asp) c.1304A>G (p.Glu435Gly) c.1253A>G (p.Glu418Gly) c.1139A>G (p.Glu380Gly) c.1244A>G (p.Glu415Gly) c.1094A>G (p.Glu365Gly) c.986A>G (p.Glu329Gly)	gnomAD v4
2	g.224503743T>G	CA350827474	CUL3	c.1286A>C (p.Glu429Ala) c.1088A>C (p.Glu363Ala) c.1214A>C (p.Glu405Ala) n.582A>C c.10A>C (p.Asn4His) c.1304A>C (p.Glu435Ala) c.1253A>C (p.Glu418Ala) c.1139A>C (p.Glu380Ala) c.1244A>C (p.Glu415Ala) c.1094A>C (p.Glu365Ala) c.986A>C (p.Glu329Ala)
2	g.224503744C>A	CA350827475	CUL3	c.1285G>T (p.Glu429Ter) c.1087G>T (p.Glu363Ter) c.1213G>T (p.Glu405Ter) n.581G>T c.9G>T (p.Leu3Phe) c.1303G>T (p.Glu435Ter) c.1252G>T (p.Glu418Ter) c.1138G>T (p.Glu380Ter) c.1243G>T (p.Glu415Ter) c.1093G>T (p.Glu365Ter) c.985G>T (p.Glu329Ter)	dbSNP gnomAD v4
2	g.224503744C=	CA1331555945	CUL3	c.1285G= (p.Glu429=) c.1087G= (p.Glu363=) c.1213G= (p.Glu405=) n.581G= c.9G= (p.Leu3=) c.1303G= (p.Glu435=) c.1252G= (p.Glu418=) c.1138G= (p.Glu380=) c.1243G= (p.Glu415=) c.1093G= (p.Glu365=) c.985G= (p.Glu329=)
2	g.224503744C>G	CA350827476	CUL3	c.1285G>C (p.Glu429Gln) c.1087G>C (p.Glu363Gln) c.1213G>C (p.Glu405Gln) n.581G>C c.9G>C (p.Leu3Phe) c.1303G>C (p.Glu435Gln) c.1252G>C (p.Glu418Gln) c.1138G>C (p.Glu380Gln) c.1243G>C (p.Glu415Gln) c.1093G>C (p.Glu365Gln) c.985G>C (p.Glu329Gln)	dbSNP
2	g.224503744C>T	CA350827477	CUL3	c.1285G>A (p.Glu429Lys) c.1087G>A (p.Glu363Lys) c.1213G>A (p.Glu405Lys) n.581G>A c.9G>A (p.Leu3=) c.1303G>A (p.Glu435Lys) c.1252G>A (p.Glu418Lys) c.1138G>A (p.Glu380Lys) c.1243G>A (p.Glu415Lys) c.1093G>A (p.Glu365Lys) c.985G>A (p.Glu329Lys)	COSMIC
2	g.224503745A=	CA1331555946	CUL3	c.1284T= (p.Phe428=) c.1086T= (p.Phe362=) c.1212T= (p.Phe404=) n.580T= c.8T= (p.Leu3=) c.1302T= (p.Phe434=) c.1251T= (p.Phe417=) c.1137T= (p.Phe379=) c.1242T= (p.Phe414=) c.1092T= (p.Phe364=) c.984T= (p.Phe328=)
2	g.224503745A>C	CA350827478	CUL3	c.1284T>G (p.Phe428Leu) c.1086T>G (p.Phe362Leu) c.1212T>G (p.Phe404Leu) n.580T>G c.8T>G (p.Leu3Trp) c.1302T>G (p.Phe434Leu) c.1251T>G (p.Phe417Leu) c.1137T>G (p.Phe379Leu) c.1242T>G (p.Phe414Leu) c.1092T>G (p.Phe364Leu) c.984T>G (p.Phe328Leu)
2	g.224503745A>G	CA350827481	CUL3	c.1284T>C (p.Phe428=) c.1086T>C (p.Phe362=) c.1212T>C (p.Phe404=) n.580T>C c.8T>C (p.Leu3Ser) c.1302T>C (p.Phe434=) c.1251T>C (p.Phe417=) c.1137T>C (p.Phe379=) c.1242T>C (p.Phe414=) c.1092T>C (p.Phe364=) c.984T>C (p.Phe328=)	dbSNP gnomAD v4
2	g.224503745A>T	CA350827480	CUL3	c.1284T>A (p.Phe428Leu) c.1086T>A (p.Phe362Leu) c.1212T>A (p.Phe404Leu) n.580T>A c.8T>A (p.Leu3Ter) c.1302T>A (p.Phe434Leu) c.1251T>A (p.Phe417Leu) c.1137T>A (p.Phe379Leu) c.1242T>A (p.Phe414Leu) c.1092T>A (p.Phe364Leu) c.984T>A (p.Phe328Leu)	dbSNP gnomAD v2 gnomAD v4
2	g.224503746A>C	CA350827483	CUL3	c.1283T>G (p.Phe428Cys) c.1085T>G (p.Phe362Cys) c.1211T>G (p.Phe404Cys) n.579T>G c.7T>G (p.Leu3Val) c.1301T>G (p.Phe434Cys) c.1250T>G (p.Phe417Cys) c.1136T>G (p.Phe379Cys) c.1241T>G (p.Phe414Cys) c.1091T>G (p.Phe364Cys) c.983T>G (p.Phe328Cys)
2	g.224503746A>G	CA350827484	CUL3	c.1283T>C (p.Phe428Ser) c.1085T>C (p.Phe362Ser) c.1211T>C (p.Phe404Ser) n.579T>C c.7T>C (p.Leu3=) c.1301T>C (p.Phe434Ser) c.1250T>C (p.Phe417Ser) c.1136T>C (p.Phe379Ser) c.1241T>C (p.Phe414Ser) c.1091T>C (p.Phe364Ser) c.983T>C (p.Phe328Ser)	dbSNP
2	g.224503746A>T	CA350827486	CUL3	c.1283T>A (p.Phe428Tyr) c.1085T>A (p.Phe362Tyr) c.1211T>A (p.Phe404Tyr) n.579T>A c.7T>A (p.Leu3Met) c.1301T>A (p.Phe434Tyr) c.1250T>A (p.Phe417Tyr) c.1136T>A (p.Phe379Tyr) c.1241T>A (p.Phe414Tyr) c.1091T>A (p.Phe364Tyr) c.983T>A (p.Phe328Tyr)	dbSNP
2	g.224503747A>C	CA350827488	CUL3	c.1282T>G (p.Phe428Val) c.1084T>G (p.Phe362Val) c.1210T>G (p.Phe404Val) n.578T>G c.6T>G (p.Tyr2Ter) c.1300T>G (p.Phe434Val) c.1249T>G (p.Phe417Val) c.1135T>G (p.Phe379Val) c.1240T>G (p.Phe414Val) c.1090T>G (p.Phe364Val) c.982T>G (p.Phe328Val)
2	g.224503747A>G	CA350827489	CUL3	c.1282T>C (p.Phe428Leu) c.1084T>C (p.Phe362Leu) c.1210T>C (p.Phe404Leu) n.578T>C c.6T>C (p.Tyr2=) c.1300T>C (p.Phe434Leu) c.1249T>C (p.Phe417Leu) c.1135T>C (p.Phe379Leu) c.1240T>C (p.Phe414Leu) c.1090T>C (p.Phe364Leu) c.982T>C (p.Phe328Leu)
2	g.224503747A>T	CA350827490	CUL3	c.1282T>A (p.Phe428Ile) c.1084T>A (p.Phe362Ile) c.1210T>A (p.Phe404Ile) n.578T>A c.6T>A (p.Tyr2Ter) c.1300T>A (p.Phe434Ile) c.1249T>A (p.Phe417Ile) c.1135T>A (p.Phe379Ile) c.1240T>A (p.Phe414Ile) c.1090T>A (p.Phe364Ile) c.982T>A (p.Phe328Ile)	dbSNP
2	g.224503748T>A	CA350827492	CUL3	c.1281A>T (p.Val427=) c.1083A>T (p.Val361=) c.1209A>T (p.Val403=) n.577A>T c.5A>T (p.Tyr2Phe) c.1299A>T (p.Val433=) c.1248A>T (p.Val416=) c.1134A>T (p.Val378=) c.1239A>T (p.Val413=) c.1089A>T (p.Val363=) c.981A>T (p.Val327=)	dbSNP
2	g.224503748T>C	CA350827494	CUL3	c.1281A>G (p.Val427=) c.1083A>G (p.Val361=) c.1209A>G (p.Val403=) n.577A>G c.5A>G (p.Tyr2Cys) c.1299A>G (p.Val433=) c.1248A>G (p.Val416=) c.1134A>G (p.Val378=) c.1239A>G (p.Val413=) c.1089A>G (p.Val363=) c.981A>G (p.Val327=)	dbSNP gnomAD v2 gnomAD v3 gnomAD v4
2	g.224503748T>G	CA350827496	CUL3	c.1281A>C (p.Val427=) c.1083A>C (p.Val361=) c.1209A>C (p.Val403=) n.577A>C c.5A>C (p.Tyr2Ser) c.1299A>C (p.Val433=) c.1248A>C (p.Val416=) c.1134A>C (p.Val378=) c.1239A>C (p.Val413=) c.1089A>C (p.Val363=) c.981A>C (p.Val327=)
2	g.224503748T=	CA1331555947	CUL3	c.1281A= (p.Val427=) c.1083A= (p.Val361=) c.1209A= (p.Val403=) n.577A= c.5A= (p.Tyr2=) c.1299A= (p.Val433=) c.1248A= (p.Val416=) c.1134A= (p.Val378=) c.1239A= (p.Val413=) c.1089A= (p.Val363=) c.981A= (p.Val327=)
2	g.224503749A>C	CA350827498	CUL3	c.1280T>G (p.Val427Gly) c.1082T>G (p.Val361Gly) c.1208T>G (p.Val403Gly) n.576T>G c.4T>G (p.Tyr2Asp) c.1298T>G (p.Val433Gly) c.1247T>G (p.Val416Gly) c.1133T>G (p.Val378Gly) c.1238T>G (p.Val413Gly) c.1088T>G (p.Val363Gly) c.980T>G (p.Val327Gly)	dbSNP
2	g.224503749A>G	CA350827499	CUL3	c.1280T>C (p.Val427Ala) c.1082T>C (p.Val361Ala) c.1208T>C (p.Val403Ala) n.576T>C c.4T>C (p.Tyr2His) c.1298T>C (p.Val433Ala) c.1247T>C (p.Val416Ala) c.1133T>C (p.Val378Ala) c.1238T>C (p.Val413Ala) c.1088T>C (p.Val363Ala) c.980T>C (p.Val327Ala)
2	g.224503749A>T	CA350827501	CUL3	c.1280T>A (p.Val427Glu) c.1082T>A (p.Val361Glu) c.1208T>A (p.Val403Glu) n.576T>A c.4T>A (p.Tyr2Asn) c.1298T>A (p.Val433Glu) c.1247T>A (p.Val416Glu) c.1133T>A (p.Val378Glu) c.1238T>A (p.Val413Glu) c.1088T>A (p.Val363Glu) c.980T>A (p.Val327Glu)	dbSNP
2	g.224503750C>A	CA350827504	CUL3	c.1279G>T (p.Val427Leu) c.1081G>T (p.Val361Leu) c.1207G>T (p.Val403Leu) n.575G>T c.3G>T (p.Met1Ile) c.1297G>T (p.Val433Leu) c.1246G>T (p.Val416Leu) c.1132G>T (p.Val378Leu) c.1237G>T (p.Val413Leu) c.1087G>T (p.Val363Leu) c.979G>T (p.Val327Leu)
2	g.224503750C>G	CA350827506	CUL3	c.1279G>C (p.Val427Leu) c.1081G>C (p.Val361Leu) c.1207G>C (p.Val403Leu) n.575G>C c.3G>C (p.Met1Ile) c.1297G>C (p.Val433Leu) c.1246G>C (p.Val416Leu) c.1132G>C (p.Val378Leu) c.1237G>C (p.Val413Leu) c.1087G>C (p.Val363Leu) c.979G>C (p.Val327Leu)	dbSNP
2	g.224503750C>T	CA350827505	CUL3	c.1279G>A (p.Val427Ile) c.1081G>A (p.Val361Ile) c.1207G>A (p.Val403Ile) n.575G>A c.3G>A (p.Met1Ile) c.1297G>A (p.Val433Ile) c.1246G>A (p.Val416Ile) c.1132G>A (p.Val378Ile) c.1237G>A (p.Val413Ile) c.1087G>A (p.Val363Ile) c.979G>A (p.Val327Ile)	dbSNP
2	g.224503751A=	CA1331555948	CUL3	c.1278T= (p.Asp426=) c.1080T= (p.Asp360=) c.1206T= (p.Asp402=) n.574T= c.2T= (p.Met1=) c.1296T= (p.Asp432=) c.1245T= (p.Asp415=) c.1131T= (p.Asp377=) c.1236T= (p.Asp412=) c.1086T= (p.Asp362=) c.978T= (p.Asp326=)
2	g.224503751A>C	CA350827508	CUL3	c.1278T>G (p.Asp426Glu) c.1080T>G (p.Asp360Glu) c.1206T>G (p.Asp402Glu) n.574T>G c.2T>G (p.Met1Arg) c.1296T>G (p.Asp432Glu) c.1245T>G (p.Asp415Glu) c.1131T>G (p.Asp377Glu) c.1236T>G (p.Asp412Glu) c.1086T>G (p.Asp362Glu) c.978T>G (p.Asp326Glu)
2	g.224503751A>G	CA350827510	CUL3	c.1278T>C (p.Asp426=) c.1080T>C (p.Asp360=) c.1206T>C (p.Asp402=) n.574T>C c.2T>C (p.Met1Thr) c.1296T>C (p.Asp432=) c.1245T>C (p.Asp415=) c.1131T>C (p.Asp377=) c.1236T>C (p.Asp412=) c.1086T>C (p.Asp362=) c.978T>C (p.Asp326=)	dbSNP gnomAD v2 gnomAD v4
2	g.224503751A>T	CA350827512	CUL3	c.1278T>A (p.Asp426Glu) c.1080T>A (p.Asp360Glu) c.1206T>A (p.Asp402Glu) n.574T>A c.2T>A (p.Met1Lys) c.1296T>A (p.Asp432Glu) c.1245T>A (p.Asp415Glu) c.1131T>A (p.Asp377Glu) c.1236T>A (p.Asp412Glu) c.1086T>A (p.Asp362Glu) c.978T>A (p.Asp326Glu)	dbSNP
2	g.224503752T>A	CA350827514	CUL3	c.1277A>T (p.Asp426Val) c.1079A>T (p.Asp360Val) c.1205A>T (p.Asp402Val) n.573A>T c.1A>T (p.Met1Leu) c.1295A>T (p.Asp432Val) c.1244A>T (p.Asp415Val) c.1130A>T (p.Asp377Val) c.1235A>T (p.Asp412Val) c.1085A>T (p.Asp362Val) c.977A>T (p.Asp326Val)
2	g.224503752T>C	CA350827515	CUL3	c.1277A>G (p.Asp426Gly) c.1079A>G (p.Asp360Gly) c.1205A>G (p.Asp402Gly) n.573A>G c.1A>G (p.Met1Val) c.1295A>G (p.Asp432Gly) c.1244A>G (p.Asp415Gly) c.1130A>G (p.Asp377Gly) c.1235A>G (p.Asp412Gly) c.1085A>G (p.Asp362Gly) c.977A>G (p.Asp326Gly)
2	g.224503752T>G	CA350827518	CUL3	c.1277A>C (p.Asp426Ala) c.1079A>C (p.Asp360Ala) c.1205A>C (p.Asp402Ala) n.573A>C c.1A>C (p.Met1Leu) c.1295A>C (p.Asp432Ala) c.1244A>C (p.Asp415Ala) c.1130A>C (p.Asp377Ala) c.1235A>C (p.Asp412Ala) c.1085A>C (p.Asp362Ala) c.977A>C (p.Asp326Ala)
2	g.224503753C>A	CA350827521	CUL3	c.1276G>T (p.Asp426Tyr) c.1078G>T (p.Asp360Tyr) c.1204G>T (p.Asp402Tyr) n.572G>T c.-1G>T (n.-1G>T) c.1294G>T (p.Asp432Tyr) c.1243G>T (p.Asp415Tyr) c.1129G>T (p.Asp377Tyr) c.1234G>T (p.Asp412Tyr) c.1084G>T (p.Asp362Tyr) c.976G>T (p.Asp326Tyr)	gnomAD v4
2	g.224503753C>G	CA350827519	CUL3	c.1276G>C (p.Asp426His) c.1078G>C (p.Asp360His) c.1204G>C (p.Asp402His) n.572G>C c.-1G>C (n.-1G>C) c.1294G>C (p.Asp432His) c.1243G>C (p.Asp415His) c.1129G>C (p.Asp377His) c.1234G>C (p.Asp412His) c.1084G>C (p.Asp362His) c.976G>C (p.Asp326His)	dbSNP COSMIC
2	g.224503753C>T	CA350827520	CUL3	c.1276G>A (p.Asp426Asn) c.1078G>A (p.Asp360Asn) c.1204G>A (p.Asp402Asn) n.572G>A c.-1G>A (n.-1G>A) c.1294G>A (p.Asp432Asn) c.1243G>A (p.Asp415Asn) c.1129G>A (p.Asp377Asn) c.1234G>A (p.Asp412Asn) c.1084G>A (p.Asp362Asn) c.976G>A (p.Asp326Asn)	dbSNP
2	g.224503754T>A	CA350827522	CUL3	c.1275A>T (p.Lys425Asn) c.1077A>T (p.Lys359Asn) c.1203A>T (p.Lys401Asn) n.571A>T c.-2A>T (n.-2A>T) c.1293A>T (p.Lys431Asn) c.1242A>T (p.Lys414Asn) c.1128A>T (p.Lys376Asn) c.1233A>T (p.Lys411Asn) c.1083A>T (p.Lys361Asn) c.975A>T (p.Lys325Asn)
2	g.224503754T>C	CA431492701	CUL3	c.1275A>G (p.Lys425=) c.1077A>G (p.Lys359=) c.1203A>G (p.Lys401=) n.571A>G c.-2A>G (n.-2A>G) c.1293A>G (p.Lys431=) c.1242A>G (p.Lys414=) c.1128A>G (p.Lys376=) c.1233A>G (p.Lys411=) c.1083A>G (p.Lys361=) c.975A>G (p.Lys325=)	dbSNP
2	g.224503754T>G	CA350827523	CUL3	c.1275A>C (p.Lys425Asn) c.1077A>C (p.Lys359Asn) c.1203A>C (p.Lys401Asn) n.571A>C c.-2A>C (n.-2A>C) c.1293A>C (p.Lys431Asn) c.1242A>C (p.Lys414Asn) c.1128A>C (p.Lys376Asn) c.1233A>C (p.Lys411Asn) c.1083A>C (p.Lys361Asn) c.975A>C (p.Lys325Asn)
2	g.224503755T>A	CA350827524	CUL3	c.1274A>T (p.Lys425Ile) c.1076A>T (p.Lys359Ile) c.1202A>T (p.Lys401Ile) n.570A>T c.-3A>T (n.-3A>T) c.1292A>T (p.Lys431Ile) c.1241A>T (p.Lys414Ile) c.1127A>T (p.Lys376Ile) c.1232A>T (p.Lys411Ile) c.1082A>T (p.Lys361Ile) c.974A>T (p.Lys325Ile)
2	g.224503755T>C	CA350827525	CUL3	c.1274A>G (p.Lys425Arg) c.1076A>G (p.Lys359Arg) c.1202A>G (p.Lys401Arg) n.570A>G c.-3A>G (n.-3A>G) c.1292A>G (p.Lys431Arg) c.1241A>G (p.Lys414Arg) c.1127A>G (p.Lys376Arg) c.1232A>G (p.Lys411Arg) c.1082A>G (p.Lys361Arg) c.974A>G (p.Lys325Arg)
2	g.224503755T>G	CA350827526	CUL3	c.1274A>C (p.Lys425Thr) c.1076A>C (p.Lys359Thr) c.1202A>C (p.Lys401Thr) n.570A>C c.-3A>C (n.-3A>C) c.1292A>C (p.Lys431Thr) c.1241A>C (p.Lys414Thr) c.1127A>C (p.Lys376Thr) c.1232A>C (p.Lys411Thr) c.1082A>C (p.Lys361Thr) c.974A>C (p.Lys325Thr)
2	g.224503756T>A	CA350827527	CUL3	c.1273A>T (p.Lys425Ter) c.1075A>T (p.Lys359Ter) c.1201A>T (p.Lys401Ter) n.569A>T c.-4A>T (n.-4A>T) c.1291A>T (p.Lys431Ter) c.1240A>T (p.Lys414Ter) c.1126A>T (p.Lys376Ter) c.1231A>T (p.Lys411Ter) c.1081A>T (p.Lys361Ter) c.973A>T (p.Lys325Ter)
2	g.224503756T>C	CA350827529	CUL3	c.1273A>G (p.Lys425Glu) c.1075A>G (p.Lys359Glu) c.1201A>G (p.Lys401Glu) n.569A>G c.-4A>G (n.-4A>G) c.1291A>G (p.Lys431Glu) c.1240A>G (p.Lys414Glu) c.1126A>G (p.Lys376Glu) c.1231A>G (p.Lys411Glu) c.1081A>G (p.Lys361Glu) c.973A>G (p.Lys325Glu)
2	g.224503756T>G	CA350827528	CUL3	c.1273A>C (p.Lys425Gln) c.1075A>C (p.Lys359Gln) c.1201A>C (p.Lys401Gln) n.569A>C c.-4A>C (n.-4A>C) c.1291A>C (p.Lys431Gln) c.1240A>C (p.Lys414Gln) c.1126A>C (p.Lys376Gln) c.1231A>C (p.Lys411Gln) c.1081A>C (p.Lys361Gln) c.973A>C (p.Lys325Gln)
2	g.224503757T>A	CA350827530	CUL3	c.1272A>T (p.Glu424Asp) c.1074A>T (p.Glu358Asp) c.1200A>T (p.Glu400Asp) n.568A>T c.-5A>T (n.-5A>T) c.1290A>T (p.Glu430Asp) c.1239A>T (p.Glu413Asp) c.1125A>T (p.Glu375Asp) c.1230A>T (p.Glu410Asp) c.1080A>T (p.Glu360Asp) c.972A>T (p.Glu324Asp)
2	g.224503757T>C	CA431492702	CUL3	c.1272A>G (p.Glu424=) c.1074A>G (p.Glu358=) c.1200A>G (p.Glu400=) n.568A>G c.-5A>G (n.-5A>G) c.1290A>G (p.Glu430=) c.1239A>G (p.Glu413=) c.1125A>G (p.Glu375=) c.1230A>G (p.Glu410=) c.1080A>G (p.Glu360=) c.972A>G (p.Glu324=)
2	g.224503757T>G	CA350827531	CUL3	c.1272A>C (p.Glu424Asp) c.1074A>C (p.Glu358Asp) c.1200A>C (p.Glu400Asp) n.568A>C c.-5A>C (n.-5A>C) c.1290A>C (p.Glu430Asp) c.1239A>C (p.Glu413Asp) c.1125A>C (p.Glu375Asp) c.1230A>C (p.Glu410Asp) c.1080A>C (p.Glu360Asp) c.972A>C (p.Glu324Asp)
2	g.224503758T>A	CA350827532	CUL3	c.1271A>T (p.Glu424Val) c.1073A>T (p.Glu358Val) c.1199A>T (p.Glu400Val) n.567A>T c.-6A>T (n.-6A>T) c.1289A>T (p.Glu430Val) c.1238A>T (p.Glu413Val) c.1124A>T (p.Glu375Val) c.1229A>T (p.Glu410Val) c.1079A>T (p.Glu360Val) c.971A>T (p.Glu324Val)	dbSNP
2	g.224503758T>C	CA350827533	CUL3	c.1271A>G (p.Glu424Gly) c.1073A>G (p.Glu358Gly) c.1199A>G (p.Glu400Gly) n.567A>G c.-6A>G (n.-6A>G) c.1289A>G (p.Glu430Gly) c.1238A>G (p.Glu413Gly) c.1124A>G (p.Glu375Gly) c.1229A>G (p.Glu410Gly) c.1079A>G (p.Glu360Gly) c.971A>G (p.Glu324Gly)	dbSNP
2	g.224503758T>G	CA350827534	CUL3	c.1271A>C (p.Glu424Ala) c.1073A>C (p.Glu358Ala) c.1199A>C (p.Glu400Ala) n.567A>C c.-6A>C (n.-6A>C) c.1289A>C (p.Glu430Ala) c.1238A>C (p.Glu413Ala) c.1124A>C (p.Glu375Ala) c.1229A>C (p.Glu410Ala) c.1079A>C (p.Glu360Ala) c.971A>C (p.Glu324Ala)
2	g.224503759C>A	CA350827535	CUL3	c.1270G>T (p.Glu424Ter) c.1072G>T (p.Glu358Ter) c.1198G>T (p.Glu400Ter) n.566G>T c.-7G>T (n.-7G>T) c.1288G>T (p.Glu430Ter) c.1237G>T (p.Glu413Ter) c.1123G>T (p.Glu375Ter) c.1228G>T (p.Glu410Ter) c.1078G>T (p.Glu360Ter) c.970G>T (p.Glu324Ter)	dbSNP
2	g.224503759C>G	CA350827536	CUL3	c.1270G>C (p.Glu424Gln) c.1072G>C (p.Glu358Gln) c.1198G>C (p.Glu400Gln) n.566G>C c.-7G>C (n.-7G>C) c.1288G>C (p.Glu430Gln) c.1237G>C (p.Glu413Gln) c.1123G>C (p.Glu375Gln) c.1228G>C (p.Glu410Gln) c.1078G>C (p.Glu360Gln) c.970G>C (p.Glu324Gln)	dbSNP
2	g.224503759C>T	CA350827537	CUL3	c.1270G>A (p.Glu424Lys) c.1072G>A (p.Glu358Lys) c.1198G>A (p.Glu400Lys) n.566G>A c.-7G>A (n.-7G>A) c.1288G>A (p.Glu430Lys) c.1237G>A (p.Glu413Lys) c.1123G>A (p.Glu375Lys) c.1228G>A (p.Glu410Lys) c.1078G>A (p.Glu360Lys) c.970G>A (p.Glu324Lys)	dbSNP
2	g.224503760T>A	CA350827538	CUL3	c.1269A>T (p.Gln423His) c.1071A>T (p.Gln357His) c.1197A>T (p.Gln399His) n.565A>T c.-8A>T (n.-8A>T) c.1287A>T (p.Gln429His) c.1236A>T (p.Gln412His) c.1122A>T (p.Gln374His) c.1227A>T (p.Gln409His) c.1077A>T (p.Gln359His) c.969A>T (p.Gln323His)
2	g.224503760T>C	CA431492703	CUL3	c.1269A>G (p.Gln423=) c.1071A>G (p.Gln357=) c.1197A>G (p.Gln399=) n.565A>G c.-8A>G (n.-8A>G) c.1287A>G (p.Gln429=) c.1236A>G (p.Gln412=) c.1122A>G (p.Gln374=) c.1227A>G (p.Gln409=) c.1077A>G (p.Gln359=) c.969A>G (p.Gln323=)
2	g.224503760T>G	CA350827539	CUL3	c.1269A>C (p.Gln423His) c.1071A>C (p.Gln357His) c.1197A>C (p.Gln399His) n.565A>C c.-8A>C (n.-8A>C) c.1287A>C (p.Gln429His) c.1236A>C (p.Gln412His) c.1122A>C (p.Gln374His) c.1227A>C (p.Gln409His) c.1077A>C (p.Gln359His) c.969A>C (p.Gln323His)
2	g.224503761T>A	CA350827540	CUL3	c.1268A>T (p.Gln423Leu) c.1070A>T (p.Gln357Leu) c.1196A>T (p.Gln399Leu) n.564A>T c.-9A>T (n.-9A>T) c.1286A>T (p.Gln429Leu) c.1235A>T (p.Gln412Leu) c.1121A>T (p.Gln374Leu) c.1226A>T (p.Gln409Leu) c.1076A>T (p.Gln359Leu) c.968A>T (p.Gln323Leu)	dbSNP
2	g.224503761T>C	CA350827542	CUL3	c.1268A>G (p.Gln423Arg) c.1070A>G (p.Gln357Arg) c.1196A>G (p.Gln399Arg) n.564A>G c.-9A>G (n.-9A>G) c.1286A>G (p.Gln429Arg) c.1235A>G (p.Gln412Arg) c.1121A>G (p.Gln374Arg) c.1226A>G (p.Gln409Arg) c.1076A>G (p.Gln359Arg) c.968A>G (p.Gln323Arg)	dbSNP
2	g.224503761T>G	CA350827541	CUL3	c.1268A>C (p.Gln423Pro) c.1070A>C (p.Gln357Pro) c.1196A>C (p.Gln399Pro) n.564A>C c.-9A>C (n.-9A>C) c.1286A>C (p.Gln429Pro) c.1235A>C (p.Gln412Pro) c.1121A>C (p.Gln374Pro) c.1226A>C (p.Gln409Pro) c.1076A>C (p.Gln359Pro) c.968A>C (p.Gln323Pro)
2	g.224503762G>A	CA350827543	CUL3	c.1267C>T (p.Gln423Ter) c.1069C>T (p.Gln357Ter) c.1195C>T (p.Gln399Ter) n.563C>T c.-10C>T (n.-10C>T) c.1285C>T (p.Gln429Ter) c.1234C>T (p.Gln412Ter) c.1120C>T (p.Gln374Ter) c.1225C>T (p.Gln409Ter) c.1075C>T (p.Gln359Ter) c.967C>T (p.Gln323Ter)	dbSNP gnomAD v4
2	g.224503762G>C	CA350827545	CUL3	c.1267C>G (p.Gln423Glu) c.1069C>G (p.Gln357Glu) c.1195C>G (p.Gln399Glu) n.563C>G c.-10C>G (n.-10C>G) c.1285C>G (p.Gln429Glu) c.1234C>G (p.Gln412Glu) c.1120C>G (p.Gln374Glu) c.1225C>G (p.Gln409Glu) c.1075C>G (p.Gln359Glu) c.967C>G (p.Gln323Glu)	dbSNP
2	g.224503762G>T	CA350827544	CUL3	c.1267C>A (p.Gln423Lys) c.1069C>A (p.Gln357Lys) c.1195C>A (p.Gln399Lys) n.563C>A c.-10C>A (n.-10C>A) c.1285C>A (p.Gln429Lys) c.1234C>A (p.Gln412Lys) c.1120C>A (p.Gln374Lys) c.1225C>A (p.Gln409Lys) c.1075C>A (p.Gln359Lys) c.967C>A (p.Gln323Lys)	gnomAD v4
2	g.224503763C>A	CA350827546	CUL3	c.1266G>T (p.Met422Ile) c.1068G>T (p.Met356Ile) c.1194G>T (p.Met398Ile) n.562G>T c.-11G>T (n.-11G>T) c.1284G>T (p.Met428Ile) c.1233G>T (p.Met411Ile) c.1119G>T (p.Met373Ile) c.1224G>T (p.Met408Ile) c.1074G>T (p.Met358Ile) c.966G>T (p.Met322Ile)	dbSNP
2	g.224503763C>G	CA350827547	CUL3	c.1266G>C (p.Met422Ile) c.1068G>C (p.Met356Ile) c.1194G>C (p.Met398Ile) n.562G>C c.-11G>C (n.-11G>C) c.1284G>C (p.Met428Ile) c.1233G>C (p.Met411Ile) c.1119G>C (p.Met373Ile) c.1224G>C (p.Met408Ile) c.1074G>C (p.Met358Ile) c.966G>C (p.Met322Ile)	dbSNP
2	g.224503763C>T	CA350827548	CUL3	c.1266G>A (p.Met422Ile) c.1068G>A (p.Met356Ile) c.1194G>A (p.Met398Ile) n.562G>A c.-11G>A (n.-11G>A) c.1284G>A (p.Met428Ile) c.1233G>A (p.Met411Ile) c.1119G>A (p.Met373Ile) c.1224G>A (p.Met408Ile) c.1074G>A (p.Met358Ile) c.966G>A (p.Met322Ile)	dbSNP gnomAD v4
2	g.224503764A>C	CA350827549	CUL3	c.1265T>G (p.Met422Arg) c.1067T>G (p.Met356Arg) c.1193T>G (p.Met398Arg) n.561T>G c.-12T>G (n.-12T>G) c.1283T>G (p.Met428Arg) c.1232T>G (p.Met411Arg) c.1118T>G (p.Met373Arg) c.1223T>G (p.Met408Arg) c.1073T>G (p.Met358Arg) c.965T>G (p.Met322Arg)
2	g.224503764A>G	CA350827550	CUL3	c.1265T>C (p.Met422Thr) c.1067T>C (p.Met356Thr) c.1193T>C (p.Met398Thr) n.561T>C c.-12T>C (n.-12T>C) c.1283T>C (p.Met428Thr) c.1232T>C (p.Met411Thr) c.1118T>C (p.Met373Thr) c.1223T>C (p.Met408Thr) c.1073T>C (p.Met358Thr) c.965T>C (p.Met322Thr)
2	g.224503764A>T	CA350827551	CUL3	c.1265T>A (p.Met422Lys) c.1067T>A (p.Met356Lys) c.1193T>A (p.Met398Lys) n.561T>A c.-12T>A (n.-12T>A) c.1283T>A (p.Met428Lys) c.1232T>A (p.Met411Lys) c.1118T>A (p.Met373Lys) c.1223T>A (p.Met408Lys) c.1073T>A (p.Met358Lys) c.965T>A (p.Met322Lys)	dbSNP
2	g.224503765T>A	CA350827552	CUL3	c.1264A>T (p.Met422Leu) c.1066A>T (p.Met356Leu) c.1192A>T (p.Met398Leu) n.560A>T c.-13A>T (n.-13A>T) c.1282A>T (p.Met428Leu) c.1231A>T (p.Met411Leu) c.1117A>T (p.Met373Leu) c.1222A>T (p.Met408Leu) c.1072A>T (p.Met358Leu) c.964A>T (p.Met322Leu)
2	g.224503765T>C	CA350827553	CUL3	c.1264A>G (p.Met422Val) c.1066A>G (p.Met356Val) c.1192A>G (p.Met398Val) n.560A>G c.-13A>G (n.-13A>G) c.1282A>G (p.Met428Val) c.1231A>G (p.Met411Val) c.1117A>G (p.Met373Val) c.1222A>G (p.Met408Val) c.1072A>G (p.Met358Val) c.964A>G (p.Met322Val)
2	g.224503765T>G	CA350827554	CUL3	c.1264A>C (p.Met422Leu) c.1066A>C (p.Met356Leu) c.1192A>C (p.Met398Leu) n.560A>C c.-13A>C (n.-13A>C) c.1282A>C (p.Met428Leu) c.1231A>C (p.Met411Leu) c.1117A>C (p.Met373Leu) c.1222A>C (p.Met408Leu) c.1072A>C (p.Met358Leu) c.964A>C (p.Met322Leu)	ClinVar
2	g.224503766A=	CA1331555949	CUL3	c.1263T= (p.Phe421=) c.1065T= (p.Phe355=) c.1191T= (p.Phe397=) n.559T= c.-14T= (n.-14T=) c.1281T= (p.Phe427=) c.1230T= (p.Phe410=) c.1116T= (p.Phe372=) c.1221T= (p.Phe407=) c.1071T= (p.Phe357=) c.963T= (p.Phe321=)
2	g.224503766A>C	CA2140020	CUL3	c.1263T>G (p.Phe421Leu) c.1065T>G (p.Phe355Leu) c.1191T>G (p.Phe397Leu) n.559T>G c.-14T>G (n.-14T>G) c.1281T>G (p.Phe427Leu) c.1230T>G (p.Phe410Leu) c.1116T>G (p.Phe372Leu) c.1221T>G (p.Phe407Leu) c.1071T>G (p.Phe357Leu) c.963T>G (p.Phe321Leu)	dbSNP ExAC gnomAD v2 gnomAD v4
2	g.224503766A>G	CA431492707	CUL3	c.1263T>C (p.Phe421=) c.1065T>C (p.Phe355=) c.1191T>C (p.Phe397=) n.559T>C c.-14T>C (n.-14T>C) c.1281T>C (p.Phe427=) c.1230T>C (p.Phe410=) c.1116T>C (p.Phe372=) c.1221T>C (p.Phe407=) c.1071T>C (p.Phe357=) c.963T>C (p.Phe321=)	dbSNP
2	g.224503766A>T	CA350827555	CUL3	c.1263T>A (p.Phe421Leu) c.1065T>A (p.Phe355Leu) c.1191T>A (p.Phe397Leu) n.559T>A c.-14T>A (n.-14T>A) c.1281T>A (p.Phe427Leu) c.1230T>A (p.Phe410Leu) c.1116T>A (p.Phe372Leu) c.1221T>A (p.Phe407Leu) c.1071T>A (p.Phe357Leu) c.963T>A (p.Phe321Leu)	dbSNP COSMIC
2	g.224503767A=	CA1331555950	CUL3	c.1262T= (p.Phe421=) c.1064T= (p.Phe355=) c.1190T= (p.Phe397=) n.558T= c.-15T= (n.-15T=) c.1280T= (p.Phe427=) c.1229T= (p.Phe410=) c.1115T= (p.Phe372=) c.1220T= (p.Phe407=) c.1070T= (p.Phe357=) c.962T= (p.Phe321=)
2	g.224503767A>C	CA350827558	CUL3	c.1262T>G (p.Phe421Cys) c.1064T>G (p.Phe355Cys) c.1190T>G (p.Phe397Cys) n.558T>G c.-15T>G (n.-15T>G) c.1280T>G (p.Phe427Cys) c.1229T>G (p.Phe410Cys) c.1115T>G (p.Phe372Cys) c.1220T>G (p.Phe407Cys) c.1070T>G (p.Phe357Cys) c.962T>G (p.Phe321Cys)	dbSNP gnomAD v3 gnomAD v4
2	g.224503767A>G	CA350827556	CUL3	c.1262T>C (p.Phe421Ser) c.1064T>C (p.Phe355Ser) c.1190T>C (p.Phe397Ser) n.558T>C c.-15T>C (n.-15T>C) c.1280T>C (p.Phe427Ser) c.1229T>C (p.Phe410Ser) c.1115T>C (p.Phe372Ser) c.1220T>C (p.Phe407Ser) c.1070T>C (p.Phe357Ser) c.962T>C (p.Phe321Ser)	dbSNP
2	g.224503767A>T	CA350827557	CUL3	c.1262T>A (p.Phe421Tyr) c.1064T>A (p.Phe355Tyr) c.1190T>A (p.Phe397Tyr) n.558T>A c.-15T>A (n.-15T>A) c.1280T>A (p.Phe427Tyr) c.1229T>A (p.Phe410Tyr) c.1115T>A (p.Phe372Tyr) c.1220T>A (p.Phe407Tyr) c.1070T>A (p.Phe357Tyr) c.962T>A (p.Phe321Tyr)	dbSNP
2	g.224503768A>C	CA350827561	CUL3	c.1261T>G (p.Phe421Val) c.1063T>G (p.Phe355Val) c.1189T>G (p.Phe397Val) n.557T>G c.-16T>G (n.-16T>G) c.1279T>G (p.Phe427Val) c.1228T>G (p.Phe410Val) c.1114T>G (p.Phe372Val) c.1219T>G (p.Phe407Val) c.1069T>G (p.Phe357Val) c.961T>G (p.Phe321Val)	dbSNP
2	g.224503768A>G	CA350827562	CUL3	c.1261T>C (p.Phe421Leu) c.1063T>C (p.Phe355Leu) c.1189T>C (p.Phe397Leu) n.557T>C c.-16T>C (n.-16T>C) c.1279T>C (p.Phe427Leu) c.1228T>C (p.Phe410Leu) c.1114T>C (p.Phe372Leu) c.1219T>C (p.Phe407Leu) c.1069T>C (p.Phe357Leu) c.961T>C (p.Phe321Leu)	dbSNP
2	g.224503768A>T	CA350827564	CUL3	c.1261T>A (p.Phe421Ile) c.1063T>A (p.Phe355Ile) c.1189T>A (p.Phe397Ile) n.557T>A c.-16T>A (n.-16T>A) c.1279T>A (p.Phe427Ile) c.1228T>A (p.Phe410Ile) c.1114T>A (p.Phe372Ile) c.1219T>A (p.Phe407Ile) c.1069T>A (p.Phe357Ile) c.961T>A (p.Phe321Ile)	dbSNP
2	g.224503769C>A	CA350827565	CUL3	c.1260G>T (p.Arg420Ser) c.1062G>T (p.Arg354Ser) c.1188G>T (p.Arg396Ser) n.556G>T c.-17G>T (n.-17G>T) c.1278G>T (p.Arg426Ser) c.1227G>T (p.Arg409Ser) c.1113G>T (p.Arg371Ser) c.1218G>T (p.Arg406Ser) c.1068G>T (p.Arg356Ser) c.960G>T (p.Arg320Ser)	dbSNP
2	g.224503769C>G	CA350827567	CUL3	c.1260G>C (p.Arg420Ser) c.1062G>C (p.Arg354Ser) c.1188G>C (p.Arg396Ser) n.556G>C c.-17G>C (n.-17G>C) c.1278G>C (p.Arg426Ser) c.1227G>C (p.Arg409Ser) c.1113G>C (p.Arg371Ser) c.1218G>C (p.Arg406Ser) c.1068G>C (p.Arg356Ser) c.960G>C (p.Arg320Ser)	dbSNP
2	g.224503769C>T	CA431492708	CUL3	c.1260G>A (p.Arg420=) c.1062G>A (p.Arg354=) c.1188G>A (p.Arg396=) n.556G>A c.-17G>A (n.-17G>A) c.1278G>A (p.Arg426=) c.1227G>A (p.Arg409=) c.1113G>A (p.Arg371=) c.1218G>A (p.Arg406=) c.1068G>A (p.Arg356=) c.960G>A (p.Arg320=)	dbSNP gnomAD v4
2	g.224503770C>A	CA350827570	CUL3	c.1259G>T (p.Arg420Met) c.1061G>T (p.Arg354Met) c.1187G>T (p.Arg396Met) n.555G>T c.-18G>T (n.-18G>T) c.1277G>T (p.Arg426Met) c.1226G>T (p.Arg409Met) c.1112G>T (p.Arg371Met) c.1217G>T (p.Arg406Met) c.1067G>T (p.Arg356Met) c.959G>T (p.Arg320Met)	dbSNP
2	g.224503770C>G	CA350827571	CUL3	c.1259G>C (p.Arg420Thr) c.1061G>C (p.Arg354Thr) c.1187G>C (p.Arg396Thr) n.555G>C c.-18G>C (n.-18G>C) c.1277G>C (p.Arg426Thr) c.1226G>C (p.Arg409Thr) c.1112G>C (p.Arg371Thr) c.1217G>C (p.Arg406Thr) c.1067G>C (p.Arg356Thr) c.959G>C (p.Arg320Thr)	dbSNP
2	g.224503770C>T	CA350827573	CUL3	c.1259G>A (p.Arg420Lys) c.1061G>A (p.Arg354Lys) c.1187G>A (p.Arg396Lys) n.555G>A c.-18G>A (n.-18G>A) c.1277G>A (p.Arg426Lys) c.1226G>A (p.Arg409Lys) c.1112G>A (p.Arg371Lys) c.1217G>A (p.Arg406Lys) c.1067G>A (p.Arg356Lys) c.959G>A (p.Arg320Lys)	dbSNP
2	g.224503771T>A	CA350827575	CUL3	c.1258A>T (p.Arg420Trp) c.1060A>T (p.Arg354Trp) c.1186A>T (p.Arg396Trp) n.554A>T c.-19A>T (n.-19A>T) c.1276A>T (p.Arg426Trp) c.1225A>T (p.Arg409Trp) c.1111A>T (p.Arg371Trp) c.1216A>T (p.Arg406Trp) c.1066A>T (p.Arg356Trp) c.958A>T (p.Arg320Trp)
2	g.224503771T>C	CA350827577	CUL3	c.1258A>G (p.Arg420Gly) c.1060A>G (p.Arg354Gly) c.1186A>G (p.Arg396Gly) n.554A>G c.-19A>G (n.-19A>G) c.1276A>G (p.Arg426Gly) c.1225A>G (p.Arg409Gly) c.1111A>G (p.Arg371Gly) c.1216A>G (p.Arg406Gly) c.1066A>G (p.Arg356Gly) c.958A>G (p.Arg320Gly)	gnomAD v4
2	g.224503771T>G	CA431492710	CUL3	c.1258A>C (p.Arg420=) c.1060A>C (p.Arg354=) c.1186A>C (p.Arg396=) n.554A>C c.-19A>C (n.-19A>C) c.1276A>C (p.Arg426=) c.1225A>C (p.Arg409=) c.1111A>C (p.Arg371=) c.1216A>C (p.Arg406=) c.1066A>C (p.Arg356=) c.958A>C (p.Arg320=)
2	g.224503772A=	CA1331555951	CUL3	c.1257T= (p.Phe419=) c.1059T= (p.Phe353=) c.1185T= (p.Phe395=) n.553T= c.-20T= (n.-20T=) c.1275T= (p.Phe425=) c.1224T= (p.Phe408=) c.1110T= (p.Phe370=) c.1215T= (p.Phe405=) c.1065T= (p.Phe355=) c.957T= (p.Phe319=)
2	g.224503772A>C	CA350827583	CUL3	c.1257T>G (p.Phe419Leu) c.1059T>G (p.Phe353Leu) c.1185T>G (p.Phe395Leu) n.553T>G c.-20T>G (n.-20T>G) c.1275T>G (p.Phe425Leu) c.1224T>G (p.Phe408Leu) c.1110T>G (p.Phe370Leu) c.1215T>G (p.Phe405Leu) c.1065T>G (p.Phe355Leu) c.957T>G (p.Phe319Leu)
2	g.224503772A>G	CA66534323	CUL3	c.1257T>C (p.Phe419=) c.1059T>C (p.Phe353=) c.1185T>C (p.Phe395=) n.553T>C c.-20T>C (n.-20T>C) c.1275T>C (p.Phe425=) c.1224T>C (p.Phe408=) c.1110T>C (p.Phe370=) c.1215T>C (p.Phe405=) c.1065T>C (p.Phe355=) c.957T>C (p.Phe319=)	dbSNP gnomAD v4
2	g.224503772A>T	CA350827580	CUL3	c.1257T>A (p.Phe419Leu) c.1059T>A (p.Phe353Leu) c.1185T>A (p.Phe395Leu) n.553T>A c.-20T>A (n.-20T>A) c.1275T>A (p.Phe425Leu) c.1224T>A (p.Phe408Leu) c.1110T>A (p.Phe370Leu) c.1215T>A (p.Phe405Leu) c.1065T>A (p.Phe355Leu) c.957T>A (p.Phe319Leu)
2	g.224503776del	CA2663372489	CUL3	c.1257del (p.Phe419LeufsTer?) c.1059del (p.Phe353LeufsTer?) c.1185del (p.Phe395LeufsTer?) n.553del c.-20del (n.-20del) c.1275del (p.Phe425LeufsTer?) c.1224del (p.Phe408LeufsTer?) c.1110del (p.Phe370LeufsTer?) c.1215del (p.Phe405LeufsTer?) c.1065del (p.Phe355LeufsTer?) c.957del (p.Phe319LeufsTer?)	gnomAD v4
2	g.224503775_224503776del	CA2701739853	CUL3	c.1256_1257del (p.Phe419Ter) c.1058_1059del (p.Phe353Ter) c.1184_1185del (p.Phe395Ter) n.552_553del c.-21_-20del (n.-21_-20del) c.1274_1275del (p.Phe425Ter) c.1223_1224del (p.Phe408Ter) c.1109_1110del (p.Phe370Ter) c.1214_1215del (p.Phe405Ter) c.1064_1065del (p.Phe355Ter) c.956_957del (p.Phe319Ter)	dbSNP
2	g.224503773A>C	CA350827586	CUL3	c.1256T>G (p.Phe419Cys) c.1058T>G (p.Phe353Cys) c.1184T>G (p.Phe395Cys) n.552T>G c.-21T>G (n.-21T>G) c.1274T>G (p.Phe425Cys) c.1223T>G (p.Phe408Cys) c.1109T>G (p.Phe370Cys) c.1214T>G (p.Phe405Cys) c.1064T>G (p.Phe355Cys) c.956T>G (p.Phe319Cys)
2	g.224503773A>G	CA350827587	CUL3	c.1256T>C (p.Phe419Ser) c.1058T>C (p.Phe353Ser) c.1184T>C (p.Phe395Ser) n.552T>C c.-21T>C (n.-21T>C) c.1274T>C (p.Phe425Ser) c.1223T>C (p.Phe408Ser) c.1109T>C (p.Phe370Ser) c.1214T>C (p.Phe405Ser) c.1064T>C (p.Phe355Ser) c.956T>C (p.Phe319Ser)
2	g.224503773A>T	CA350827589	CUL3	c.1256T>A (p.Phe419Tyr) c.1058T>A (p.Phe353Tyr) c.1184T>A (p.Phe395Tyr) n.552T>A c.-21T>A (n.-21T>A) c.1274T>A (p.Phe425Tyr) c.1223T>A (p.Phe408Tyr) c.1109T>A (p.Phe370Tyr) c.1214T>A (p.Phe405Tyr) c.1064T>A (p.Phe355Tyr) c.956T>A (p.Phe319Tyr)
2	g.224503774A>C	CA350827591	CUL3	c.1255T>G (p.Phe419Val) c.1057T>G (p.Phe353Val) c.1183T>G (p.Phe395Val) n.551T>G c.-22T>G (n.-22T>G) c.1273T>G (p.Phe425Val) c.1222T>G (p.Phe408Val) c.1108T>G (p.Phe370Val) c.1213T>G (p.Phe405Val) c.1063T>G (p.Phe355Val) c.955T>G (p.Phe319Val)
2	g.224503774A>G	CA350827593	CUL3	c.1255T>C (p.Phe419Leu) c.1057T>C (p.Phe353Leu) c.1183T>C (p.Phe395Leu) n.551T>C c.-22T>C (n.-22T>C) c.1273T>C (p.Phe425Leu) c.1222T>C (p.Phe408Leu) c.1108T>C (p.Phe370Leu) c.1213T>C (p.Phe405Leu) c.1063T>C (p.Phe355Leu) c.955T>C (p.Phe319Leu)	gnomAD v4
2	g.224503774A>T	CA350827595	CUL3	c.1255T>A (p.Phe419Ile) c.1057T>A (p.Phe353Ile) c.1183T>A (p.Phe395Ile) n.551T>A c.-22T>A (n.-22T>A) c.1273T>A (p.Phe425Ile) c.1222T>A (p.Phe408Ile) c.1108T>A (p.Phe370Ile) c.1213T>A (p.Phe405Ile) c.1063T>A (p.Phe355Ile) c.955T>A (p.Phe319Ile)	dbSNP
2	g.224503775A=	CA1331555952	CUL3	c.1254T= (p.Leu418=) c.1056T= (p.Leu352=) c.1182T= (p.Leu394=) n.550T= c.-23T= (n.-23T=) c.1272T= (p.Leu424=) c.1221T= (p.Leu407=) c.1107T= (p.Leu369=) c.1212T= (p.Leu404=) c.1062T= (p.Leu354=) c.954T= (p.Leu318=)
2	g.224503775A>C	CA431492711	CUL3	c.1254T>G (p.Leu418=) c.1056T>G (p.Leu352=) c.1182T>G (p.Leu394=) n.550T>G c.-23T>G (n.-23T>G) c.1272T>G (p.Leu424=) c.1221T>G (p.Leu407=) c.1107T>G (p.Leu369=) c.1212T>G (p.Leu404=) c.1062T>G (p.Leu354=) c.954T>G (p.Leu318=)
2	g.224503775A>G	CA431492712	CUL3	c.1254T>C (p.Leu418=) c.1056T>C (p.Leu352=) c.1182T>C (p.Leu394=) n.550T>C c.-23T>C (n.-23T>C) c.1272T>C (p.Leu424=) c.1221T>C (p.Leu407=) c.1107T>C (p.Leu369=) c.1212T>C (p.Leu404=) c.1062T>C (p.Leu354=) c.954T>C (p.Leu318=)	dbSNP gnomAD v3 gnomAD v4
2	g.224503775A>T	CA431492713	CUL3	c.1254T>A (p.Leu418=) c.1056T>A (p.Leu352=) c.1182T>A (p.Leu394=) n.550T>A c.-23T>A (n.-23T>A) c.1272T>A (p.Leu424=) c.1221T>A (p.Leu407=) c.1107T>A (p.Leu369=) c.1212T>A (p.Leu404=) c.1062T>A (p.Leu354=) c.954T>A (p.Leu318=)
2	g.224503776A>C	CA350827597	CUL3	c.1253T>G (p.Leu418Arg) c.1055T>G (p.Leu352Arg) c.1181T>G (p.Leu394Arg) n.549T>G c.-24T>G (n.-24T>G) c.1271T>G (p.Leu424Arg) c.1220T>G (p.Leu407Arg) c.1106T>G (p.Leu369Arg) c.1211T>G (p.Leu404Arg) c.1061T>G (p.Leu354Arg) c.953T>G (p.Leu318Arg)
2	g.224503776A>G	CA350827599	CUL3	c.1253T>C (p.Leu418Pro) c.1055T>C (p.Leu352Pro) c.1181T>C (p.Leu394Pro) n.549T>C c.-24T>C (n.-24T>C) c.1271T>C (p.Leu424Pro) c.1220T>C (p.Leu407Pro) c.1106T>C (p.Leu369Pro) c.1211T>C (p.Leu404Pro) c.1061T>C (p.Leu354Pro) c.953T>C (p.Leu318Pro)	dbSNP gnomAD v4
2	g.224503776A>T	CA350827601	CUL3	c.1253T>A (p.Leu418His) c.1055T>A (p.Leu352His) c.1181T>A (p.Leu394His) n.549T>A c.-24T>A (n.-24T>A) c.1271T>A (p.Leu424His) c.1220T>A (p.Leu407His) c.1106T>A (p.Leu369His) c.1211T>A (p.Leu404His) c.1061T>A (p.Leu354His) c.953T>A (p.Leu318His)	dbSNP
2	g.224503777G>A	CA350827603	CUL3	c.1252C>T (p.Leu418Phe) c.1054C>T (p.Leu352Phe) c.1180C>T (p.Leu394Phe) n.548C>T c.-25C>T (n.-25C>T) c.1270C>T (p.Leu424Phe) c.1219C>T (p.Leu407Phe) c.1105C>T (p.Leu369Phe) c.1210C>T (p.Leu404Phe) c.1060C>T (p.Leu354Phe) c.952C>T (p.Leu318Phe)	dbSNP gnomAD v2 gnomAD v4
2	g.224503777G>C	CA350827605	CUL3	c.1252C>G (p.Leu418Val) c.1054C>G (p.Leu352Val) c.1180C>G (p.Leu394Val) n.548C>G c.-25C>G (n.-25C>G) c.1270C>G (p.Leu424Val) c.1219C>G (p.Leu407Val) c.1105C>G (p.Leu369Val) c.1210C>G (p.Leu404Val) c.1060C>G (p.Leu354Val) c.952C>G (p.Leu318Val)	dbSNP
2	g.224503777G=	CA1331555953	CUL3	c.1252C= (p.Leu418=) c.1054C= (p.Leu352=) c.1180C= (p.Leu394=) n.548C= c.-25C= (n.-25C=) c.1270C= (p.Leu424=) c.1219C= (p.Leu407=) c.1105C= (p.Leu369=) c.1210C= (p.Leu404=) c.1060C= (p.Leu354=) c.952C= (p.Leu318=)
2	g.224503777G>T	CA350827607	CUL3	c.1252C>A (p.Leu418Ile) c.1054C>A (p.Leu352Ile) c.1180C>A (p.Leu394Ile) n.548C>A c.-25C>A (n.-25C>A) c.1270C>A (p.Leu424Ile) c.1219C>A (p.Leu407Ile) c.1105C>A (p.Leu369Ile) c.1210C>A (p.Leu404Ile) c.1060C>A (p.Leu354Ile) c.952C>A (p.Leu318Ile)	dbSNP
2	g.224503778G>A	CA431492715	CUL3	c.1251C>T (p.Val417=) c.1053C>T (p.Val351=) c.1179C>T (p.Val393=) n.547C>T c.-26C>T (n.-26C>T) c.1269C>T (p.Val423=) c.1218C>T (p.Val406=) c.1104C>T (p.Val368=) c.1209C>T (p.Val403=) c.1059C>T (p.Val353=) c.951C>T (p.Val317=)	dbSNP
2	g.224503778G>C	CA431492716	CUL3	c.1251C>G (p.Val417=) c.1053C>G (p.Val351=) c.1179C>G (p.Val393=) n.547C>G c.-26C>G (n.-26C>G) c.1269C>G (p.Val423=) c.1218C>G (p.Val406=) c.1104C>G (p.Val368=) c.1209C>G (p.Val403=) c.1059C>G (p.Val353=) c.951C>G (p.Val317=)	dbSNP
2	g.224503778G>T	CA431492717	CUL3	c.1251C>A (p.Val417=) c.1053C>A (p.Val351=) c.1179C>A (p.Val393=) n.547C>A c.-26C>A (n.-26C>A) c.1269C>A (p.Val423=) c.1218C>A (p.Val406=) c.1104C>A (p.Val368=) c.1209C>A (p.Val403=) c.1059C>A (p.Val353=) c.951C>A (p.Val317=)	dbSNP gnomAD v4
2	g.224503779A>C	CA350827612	CUL3	c.1250T>G (p.Val417Gly) c.1052T>G (p.Val351Gly) c.1178T>G (p.Val393Gly) n.546T>G c.-27T>G (n.-27T>G) c.1268T>G (p.Val423Gly) c.1217T>G (p.Val406Gly) c.1103T>G (p.Val368Gly) c.1208T>G (p.Val403Gly) c.1058T>G (p.Val353Gly) c.950T>G (p.Val317Gly)
2	g.224503779A>G	CA350827608	CUL3	c.1250T>C (p.Val417Ala) c.1052T>C (p.Val351Ala) c.1178T>C (p.Val393Ala) n.546T>C c.-27T>C (n.-27T>C) c.1268T>C (p.Val423Ala) c.1217T>C (p.Val406Ala) c.1103T>C (p.Val368Ala) c.1208T>C (p.Val403Ala) c.1058T>C (p.Val353Ala) c.950T>C (p.Val317Ala)
2	g.224503779A>T	CA350827610	CUL3	c.1250T>A (p.Val417Asp) c.1052T>A (p.Val351Asp) c.1178T>A (p.Val393Asp) n.546T>A c.-27T>A (n.-27T>A) c.1268T>A (p.Val423Asp) c.1217T>A (p.Val406Asp) c.1103T>A (p.Val368Asp) c.1208T>A (p.Val403Asp) c.1058T>A (p.Val353Asp) c.950T>A (p.Val317Asp)
2	g.224503780C>A	CA350827614	CUL3	c.1249G>T (p.Val417Phe) c.1051G>T (p.Val351Phe) c.1177G>T (p.Val393Phe) n.545G>T c.-28G>T (n.-28G>T) c.1267G>T (p.Val423Phe) c.1216G>T (p.Val406Phe) c.1102G>T (p.Val368Phe) c.1207G>T (p.Val403Phe) c.1057G>T (p.Val353Phe) c.949G>T (p.Val317Phe)	dbSNP gnomAD v4
2	g.224503780C=	CA1331555954	CUL3	c.1249G= (p.Val417=) c.1051G= (p.Val351=) c.1177G= (p.Val393=) n.545G= c.-28G= (n.-28G=) c.1267G= (p.Val423=) c.1216G= (p.Val406=) c.1102G= (p.Val368=) c.1207G= (p.Val403=) c.1057G= (p.Val353=) c.949G= (p.Val317=)
2	g.224503780C>G	CA350827615	CUL3	c.1249G>C (p.Val417Leu) c.1051G>C (p.Val351Leu) c.1177G>C (p.Val393Leu) n.545G>C c.-28G>C (n.-28G>C) c.1267G>C (p.Val423Leu) c.1216G>C (p.Val406Leu) c.1102G>C (p.Val368Leu) c.1207G>C (p.Val403Leu) c.1057G>C (p.Val353Leu) c.949G>C (p.Val317Leu)	dbSNP
2	g.224503780C>T	CA350827617	CUL3	c.1249G>A (p.Val417Ile) c.1051G>A (p.Val351Ile) c.1177G>A (p.Val393Ile) n.545G>A c.-28G>A (n.-28G>A) c.1267G>A (p.Val423Ile) c.1216G>A (p.Val406Ile) c.1102G>A (p.Val368Ile) c.1207G>A (p.Val403Ile) c.1057G>A (p.Val353Ile) c.949G>A (p.Val317Ile)	dbSNP gnomAD v2 gnomAD v4
2	g.224503781C>A	CA350827618	CUL3	c.1248G>T (p.Met416Ile) c.1050G>T (p.Met350Ile) c.1176G>T (p.Met392Ile) n.544G>T c.-29G>T (n.-29G>T) c.1266G>T (p.Met422Ile) c.1215G>T (p.Met405Ile) c.1101G>T (p.Met367Ile) c.1206G>T (p.Met402Ile) c.1056G>T (p.Met352Ile) c.948G>T (p.Met316Ile)	dbSNP
2	g.224503781C>G	CA350827620	CUL3	c.1248G>C (p.Met416Ile) c.1050G>C (p.Met350Ile) c.1176G>C (p.Met392Ile) n.544G>C c.-29G>C (n.-29G>C) c.1266G>C (p.Met422Ile) c.1215G>C (p.Met405Ile) c.1101G>C (p.Met367Ile) c.1206G>C (p.Met402Ile) c.1056G>C (p.Met352Ile) c.948G>C (p.Met316Ile)	dbSNP
2	g.224503781C>T	CA350827622	CUL3	c.1248G>A (p.Met416Ile) c.1050G>A (p.Met350Ile) c.1176G>A (p.Met392Ile) n.544G>A c.-29G>A (n.-29G>A) c.1266G>A (p.Met422Ile) c.1215G>A (p.Met405Ile) c.1101G>A (p.Met367Ile) c.1206G>A (p.Met402Ile) c.1056G>A (p.Met352Ile) c.948G>A (p.Met316Ile)	ClinVar dbSNP
2	g.224503782A>C	CA350827624	CUL3	c.1247T>G (p.Met416Arg) c.1049T>G (p.Met350Arg) c.1175T>G (p.Met392Arg) n.543T>G c.-30T>G (n.-30T>G) c.1265T>G (p.Met422Arg) c.1214T>G (p.Met405Arg) c.1100T>G (p.Met367Arg) c.1205T>G (p.Met402Arg) c.1055T>G (p.Met352Arg) c.947T>G (p.Met316Arg)	dbSNP
2	g.224503782A>G	CA350827625	CUL3	c.1247T>C (p.Met416Thr) c.1049T>C (p.Met350Thr) c.1175T>C (p.Met392Thr) n.543T>C c.-30T>C (n.-30T>C) c.1265T>C (p.Met422Thr) c.1214T>C (p.Met405Thr) c.1100T>C (p.Met367Thr) c.1205T>C (p.Met402Thr) c.1055T>C (p.Met352Thr) c.947T>C (p.Met316Thr)
2	g.224503782A>T	CA350827627	CUL3	c.1247T>A (p.Met416Lys) c.1049T>A (p.Met350Lys) c.1175T>A (p.Met392Lys) n.543T>A c.-30T>A (n.-30T>A) c.1265T>A (p.Met422Lys) c.1214T>A (p.Met405Lys) c.1100T>A (p.Met367Lys) c.1205T>A (p.Met402Lys) c.1055T>A (p.Met352Lys) c.947T>A (p.Met316Lys)	dbSNP
2	g.224503783T>A	CA350827629	CUL3	c.1246A>T (p.Met416Leu) c.1048A>T (p.Met350Leu) c.1174A>T (p.Met392Leu) n.542A>T c.-31A>T (n.-31A>T) c.1264A>T (p.Met422Leu) c.1213A>T (p.Met405Leu) c.1099A>T (p.Met367Leu) c.1204A>T (p.Met402Leu) c.1054A>T (p.Met352Leu) c.946A>T (p.Met316Leu)	dbSNP
2	g.224503783T>C	CA350827631	CUL3	c.1246A>G (p.Met416Val) c.1048A>G (p.Met350Val) c.1174A>G (p.Met392Val) n.542A>G c.-31A>G (n.-31A>G) c.1264A>G (p.Met422Val) c.1213A>G (p.Met405Val) c.1099A>G (p.Met367Val) c.1204A>G (p.Met402Val) c.1054A>G (p.Met352Val) c.946A>G (p.Met316Val)	gnomAD v4
2	g.224503783T>G	CA350827633	CUL3	c.1246A>C (p.Met416Leu) c.1048A>C (p.Met350Leu) c.1174A>C (p.Met392Leu) n.542A>C c.-31A>C (n.-31A>C) c.1264A>C (p.Met422Leu) c.1213A>C (p.Met405Leu) c.1099A>C (p.Met367Leu) c.1204A>C (p.Met402Leu) c.1054A>C (p.Met352Leu) c.946A>C (p.Met316Leu)
2	g.224503784T>A	CA431492718	CUL3	c.1245A>T (p.Ala415=) c.1047A>T (p.Ala349=) c.1173A>T (p.Ala391=) n.541A>T c.-32A>T (n.-32A>T) c.1263A>T (p.Ala421=) c.1212A>T (p.Ala404=) c.1098A>T (p.Ala366=) c.1203A>T (p.Ala401=) c.1053A>T (p.Ala351=) c.945A>T (p.Ala315=)	dbSNP
2	g.224503784T>C	CA431492719	CUL3	c.1245A>G (p.Ala415=) c.1047A>G (p.Ala349=) c.1173A>G (p.Ala391=) n.541A>G c.-32A>G (n.-32A>G) c.1263A>G (p.Ala421=) c.1212A>G (p.Ala404=) c.1098A>G (p.Ala366=) c.1203A>G (p.Ala401=) c.1053A>G (p.Ala351=) c.945A>G (p.Ala315=)
2	g.224503784T>G	CA431492720	CUL3	c.1245A>C (p.Ala415=) c.1047A>C (p.Ala349=) c.1173A>C (p.Ala391=) n.541A>C c.-32A>C (n.-32A>C) c.1263A>C (p.Ala421=) c.1212A>C (p.Ala404=) c.1098A>C (p.Ala366=) c.1203A>C (p.Ala401=) c.1053A>C (p.Ala351=) c.945A>C (p.Ala315=)
2	g.224503785G>A	CA350827637	CUL3	c.1244C>T (p.Ala415Val) c.1046C>T (p.Ala349Val) c.1172C>T (p.Ala391Val) n.540C>T c.-33C>T (n.-33C>T) c.1262C>T (p.Ala421Val) c.1211C>T (p.Ala404Val) c.1097C>T (p.Ala366Val) c.1202C>T (p.Ala401Val) c.1052C>T (p.Ala351Val) c.944C>T (p.Ala315Val)
2	g.224503785G>C	CA350827639	CUL3	c.1244C>G (p.Ala415Gly) c.1046C>G (p.Ala349Gly) c.1172C>G (p.Ala391Gly) n.540C>G c.-33C>G (n.-33C>G) c.1262C>G (p.Ala421Gly) c.1211C>G (p.Ala404Gly) c.1097C>G (p.Ala366Gly) c.1202C>G (p.Ala401Gly) c.1052C>G (p.Ala351Gly) c.944C>G (p.Ala315Gly)	dbSNP
2	g.224503785G>T	CA350827635	CUL3	c.1244C>A (p.Ala415Glu) c.1046C>A (p.Ala349Glu) c.1172C>A (p.Ala391Glu) n.540C>A c.-33C>A (n.-33C>A) c.1262C>A (p.Ala421Glu) c.1211C>A (p.Ala404Glu) c.1097C>A (p.Ala366Glu) c.1202C>A (p.Ala401Glu) c.1052C>A (p.Ala351Glu) c.944C>A (p.Ala315Glu)	dbSNP
2	g.224503786C>A	CA350827643	CUL3	c.1243G>T (p.Ala415Ser) c.1045G>T (p.Ala349Ser) c.1171G>T (p.Ala391Ser) n.539G>T c.-34G>T (n.-34G>T) c.1261G>T (p.Ala421Ser) c.1210G>T (p.Ala404Ser) c.1096G>T (p.Ala366Ser) c.1201G>T (p.Ala401Ser) c.1051G>T (p.Ala351Ser) c.943G>T (p.Ala315Ser)	gnomAD v4
2	g.224503786C>G	CA350827641	CUL3	c.1243G>C (p.Ala415Pro) c.1045G>C (p.Ala349Pro) c.1171G>C (p.Ala391Pro) n.539G>C c.-34G>C (n.-34G>C) c.1261G>C (p.Ala421Pro) c.1210G>C (p.Ala404Pro) c.1096G>C (p.Ala366Pro) c.1201G>C (p.Ala401Pro) c.1051G>C (p.Ala351Pro) c.943G>C (p.Ala315Pro)	dbSNP
2	g.224503786C>T	CA350827644	CUL3	c.1243G>A (p.Ala415Thr) c.1045G>A (p.Ala349Thr) c.1171G>A (p.Ala391Thr) n.539G>A c.-34G>A (n.-34G>A) c.1261G>A (p.Ala421Thr) c.1210G>A (p.Ala404Thr) c.1096G>A (p.Ala366Thr) c.1201G>A (p.Ala401Thr) c.1051G>A (p.Ala351Thr) c.943G>A (p.Ala315Thr)	gnomAD v4
2	g.224503787T>A	CA350827645	CUL3	c.1242A>T (p.Lys414Asn) c.1044A>T (p.Lys348Asn) c.1170A>T (p.Lys390Asn) n.538A>T c.-35A>T (n.-35A>T) c.1260A>T (p.Lys420Asn) c.1209A>T (p.Lys403Asn) c.1095A>T (p.Lys365Asn) c.1200A>T (p.Lys400Asn) c.1050A>T (p.Lys350Asn) c.942A>T (p.Lys314Asn)	dbSNP
2	g.224503787T>C	CA431492721	CUL3	c.1242A>G (p.Lys414=) c.1044A>G (p.Lys348=) c.1170A>G (p.Lys390=) n.538A>G c.-35A>G (n.-35A>G) c.1260A>G (p.Lys420=) c.1209A>G (p.Lys403=) c.1095A>G (p.Lys365=) c.1200A>G (p.Lys400=) c.1050A>G (p.Lys350=) c.942A>G (p.Lys314=)
2	g.224503787T>G	CA350827646	CUL3	c.1242A>C (p.Lys414Asn) c.1044A>C (p.Lys348Asn) c.1170A>C (p.Lys390Asn) n.538A>C c.-35A>C (n.-35A>C) c.1260A>C (p.Lys420Asn) c.1209A>C (p.Lys403Asn) c.1095A>C (p.Lys365Asn) c.1200A>C (p.Lys400Asn) c.1050A>C (p.Lys350Asn) c.942A>C (p.Lys314Asn)
2	g.224503788T>A	CA350827648	CUL3	c.1241A>T (p.Lys414Ile) c.1043A>T (p.Lys348Ile) c.1169A>T (p.Lys390Ile) n.537A>T c.-36A>T (n.-36A>T) c.1259A>T (p.Lys420Ile) c.1208A>T (p.Lys403Ile) c.1094A>T (p.Lys365Ile) c.1199A>T (p.Lys400Ile) c.1049A>T (p.Lys350Ile) c.941A>T (p.Lys314Ile)	dbSNP
2	g.224503788T>C	CA350827649	CUL3	c.1241A>G (p.Lys414Arg) c.1043A>G (p.Lys348Arg) c.1169A>G (p.Lys390Arg) n.537A>G c.-36A>G (n.-36A>G) c.1259A>G (p.Lys420Arg) c.1208A>G (p.Lys403Arg) c.1094A>G (p.Lys365Arg) c.1199A>G (p.Lys400Arg) c.1049A>G (p.Lys350Arg) c.941A>G (p.Lys314Arg)
2	g.224503788T>G	CA350827650	CUL3	c.1241A>C (p.Lys414Thr) c.1043A>C (p.Lys348Thr) c.1169A>C (p.Lys390Thr) n.537A>C c.-36A>C (n.-36A>C) c.1259A>C (p.Lys420Thr) c.1208A>C (p.Lys403Thr) c.1094A>C (p.Lys365Thr) c.1199A>C (p.Lys400Thr) c.1049A>C (p.Lys350Thr) c.941A>C (p.Lys314Thr)
2	g.224503789T>A	CA350827653	CUL3	c.1240A>T (p.Lys414Ter) c.1042A>T (p.Lys348Ter) c.1168A>T (p.Lys390Ter) n.536A>T c.-37A>T (n.-37A>T) c.1258A>T (p.Lys420Ter) c.1207A>T (p.Lys403Ter) c.1093A>T (p.Lys365Ter) c.1198A>T (p.Lys400Ter) c.1048A>T (p.Lys350Ter) c.940A>T (p.Lys314Ter)	dbSNP
2	g.224503789T>C	CA350827654	CUL3	c.1240A>G (p.Lys414Glu) c.1042A>G (p.Lys348Glu) c.1168A>G (p.Lys390Glu) n.536A>G c.-37A>G (n.-37A>G) c.1258A>G (p.Lys420Glu) c.1207A>G (p.Lys403Glu) c.1093A>G (p.Lys365Glu) c.1198A>G (p.Lys400Glu) c.1048A>G (p.Lys350Glu) c.940A>G (p.Lys314Glu)	dbSNP
2	g.224503789T>G	CA350827656	CUL3	c.1240A>C (p.Lys414Gln) c.1042A>C (p.Lys348Gln) c.1168A>C (p.Lys390Gln) n.536A>C c.-37A>C (n.-37A>C) c.1258A>C (p.Lys420Gln) c.1207A>C (p.Lys403Gln) c.1093A>C (p.Lys365Gln) c.1198A>C (p.Lys400Gln) c.1048A>C (p.Lys350Gln) c.940A>C (p.Lys314Gln)
2	g.224503789_224503790delinsTA	CA1331555955	CUL3	c.1239_1240delinsTA (p.Asp413=) c.1041_1042delinsTA (p.Asp347=) c.1167_1168delinsTA (p.Asp389=) n.535_536delinsTA c.-38_-37delinsTA (n.-38_-37delinsTA) c.1257_1258delinsTA (p.Asp419=) c.1206_1207delinsTA (p.Asp402=) c.1092_1093delinsTA (p.Asp364=) c.1197_1198delinsTA (p.Asp399=) c.1047_1048delinsTA (p.Asp349=) c.939_940delinsTA (p.Asp313=)
2	g.224503790del	CA1139655021	CUL3	c.1239del (p.Asp413GlufsTer?) c.1041del (p.Asp347GlufsTer?) c.1167del (p.Asp389GlufsTer?) n.535del c.-38del (n.-38del) c.1257del (p.Asp419GlufsTer?) c.1206del (p.Asp402GlufsTer?) c.1092del (p.Asp364GlufsTer?) c.1197del (p.Asp399GlufsTer?) c.1047del (p.Asp349GlufsTer?) c.939del (p.Asp313GlufsTer?)	ClinVar dbSNP
2	g.224503790A>C	CA350827658	CUL3	c.1239T>G (p.Asp413Glu) c.1041T>G (p.Asp347Glu) c.1167T>G (p.Asp389Glu) n.535T>G c.-38T>G (n.-38T>G) c.1257T>G (p.Asp419Glu) c.1206T>G (p.Asp402Glu) c.1092T>G (p.Asp364Glu) c.1197T>G (p.Asp399Glu) c.1047T>G (p.Asp349Glu) c.939T>G (p.Asp313Glu)
2	g.224503790A>G	CA431492722	CUL3	c.1239T>C (p.Asp413=) c.1041T>C (p.Asp347=) c.1167T>C (p.Asp389=) n.535T>C c.-38T>C (n.-38T>C) c.1257T>C (p.Asp419=) c.1206T>C (p.Asp402=) c.1092T>C (p.Asp364=) c.1197T>C (p.Asp399=) c.1047T>C (p.Asp349=) c.939T>C (p.Asp313=)
2	g.224503790A>T	CA350827659	CUL3	c.1239T>A (p.Asp413Glu) c.1041T>A (p.Asp347Glu) c.1167T>A (p.Asp389Glu) n.535T>A c.-38T>A (n.-38T>A) c.1257T>A (p.Asp419Glu) c.1206T>A (p.Asp402Glu) c.1092T>A (p.Asp364Glu) c.1197T>A (p.Asp399Glu) c.1047T>A (p.Asp349Glu) c.939T>A (p.Asp313Glu)	dbSNP
2	g.224503791T>A	CA350827664	CUL3	c.1238A>T (p.Asp413Val) c.1040A>T (p.Asp347Val) c.1166A>T (p.Asp389Val) n.534A>T c.-39A>T (n.-39A>T) c.1256A>T (p.Asp419Val) c.1205A>T (p.Asp402Val) c.1091A>T (p.Asp364Val) c.1196A>T (p.Asp399Val) c.1046A>T (p.Asp349Val) c.938A>T (p.Asp313Val)
2	g.224503791T>C	CA129109	CUL3	c.1238A>G (p.Asp413Gly) c.1040A>G (p.Asp347Gly) c.1166A>G (p.Asp389Gly) n.534A>G c.-39A>G (n.-39A>G) c.1256A>G (p.Asp419Gly) c.1205A>G (p.Asp402Gly) c.1091A>G (p.Asp364Gly) c.1196A>G (p.Asp399Gly) c.1046A>G (p.Asp349Gly) c.938A>G (p.Asp313Gly)	ClinVar dbSNP
2	g.224503791T>G	CA350827661	CUL3	c.1238A>C (p.Asp413Ala) c.1040A>C (p.Asp347Ala) c.1166A>C (p.Asp389Ala) n.534A>C c.-39A>C (n.-39A>C) c.1256A>C (p.Asp419Ala) c.1205A>C (p.Asp402Ala) c.1091A>C (p.Asp364Ala) c.1196A>C (p.Asp399Ala) c.1046A>C (p.Asp349Ala) c.938A>C (p.Asp313Ala)
2	g.224503791T=	CA1331555956	CUL3	c.1238A= (p.Asp413=) c.1040A= (p.Asp347=) c.1166A= (p.Asp389=) n.534A= c.-39A= (n.-39A=) c.1256A= (p.Asp419=) c.1205A= (p.Asp402=) c.1091A= (p.Asp364=) c.1196A= (p.Asp399=) c.1046A= (p.Asp349=) c.938A= (p.Asp313=)
2	g.224503792C>A	CA350827666	CUL3	c.1237G>T (p.Asp413Tyr) c.1039G>T (p.Asp347Tyr) c.1165G>T (p.Asp389Tyr) n.533G>T c.-40G>T (n.-40G>T) c.1255G>T (p.Asp419Tyr) c.1204G>T (p.Asp402Tyr) c.1090G>T (p.Asp364Tyr) c.1195G>T (p.Asp399Tyr) c.1045G>T (p.Asp349Tyr) c.937G>T (p.Asp313Tyr)	dbSNP
2	g.224503792C>G	CA350827668	CUL3	c.1237G>C (p.Asp413His) c.1039G>C (p.Asp347His) c.1165G>C (p.Asp389His) n.533G>C c.-40G>C (n.-40G>C) c.1255G>C (p.Asp419His) c.1204G>C (p.Asp402His) c.1090G>C (p.Asp364His) c.1195G>C (p.Asp399His) c.1045G>C (p.Asp349His) c.937G>C (p.Asp313His)	dbSNP
2	g.224503792C>T	CA350827669	CUL3	c.1237G>A (p.Asp413Asn) c.1039G>A (p.Asp347Asn) c.1165G>A (p.Asp389Asn) n.533G>A c.-40G>A (n.-40G>A) c.1255G>A (p.Asp419Asn) c.1204G>A (p.Asp402Asn) c.1090G>A (p.Asp364Asn) c.1195G>A (p.Asp399Asn) c.1045G>A (p.Asp349Asn) c.937G>A (p.Asp313Asn)	dbSNP
2	g.224503793C>A	CA350827671	CUL3	c.1236G>T (p.Leu412Phe) c.1038G>T (p.Leu346Phe) c.1164G>T (p.Leu388Phe) n.532G>T c.-41G>T (n.-41G>T) c.1254G>T (p.Leu418Phe) c.1203G>T (p.Leu401Phe) c.1089G>T (p.Leu363Phe) c.1194G>T (p.Leu398Phe) c.1044G>T (p.Leu348Phe) c.936G>T (p.Leu312Phe)	dbSNP
2	g.224503793C=	CA1331555957	CUL3	c.1236G= (p.Leu412=) c.1038G= (p.Leu346=) c.1164G= (p.Leu388=) n.532G= c.-41G= (n.-41G=) c.1254G= (p.Leu418=) c.1203G= (p.Leu401=) c.1089G= (p.Leu363=) c.1194G= (p.Leu398=) c.1044G= (p.Leu348=) c.936G= (p.Leu312=)
2	g.224503793C>G	CA350827673	CUL3	c.1236G>C (p.Leu412Phe) c.1038G>C (p.Leu346Phe) c.1164G>C (p.Leu388Phe) n.532G>C c.-41G>C (n.-41G>C) c.1254G>C (p.Leu418Phe) c.1203G>C (p.Leu401Phe) c.1089G>C (p.Leu363Phe) c.1194G>C (p.Leu398Phe) c.1044G>C (p.Leu348Phe) c.936G>C (p.Leu312Phe)	dbSNP
2	g.224503793C>T	CA269960	CUL3	c.1236G>A (p.Leu412=) c.1038G>A (p.Leu346=) c.1164G>A (p.Leu388=) n.532G>A c.-41G>A (n.-41G>A) c.1254G>A (p.Leu418=) c.1203G>A (p.Leu401=) c.1089G>A (p.Leu363=) c.1194G>A (p.Leu398=) c.1044G>A (p.Leu348=) c.936G>A (p.Leu312=)	ClinVar dbSNP
2	g.224503794A>C	CA350827676	CUL3	c.1235T>G (p.Leu412Trp) c.1037T>G (p.Leu346Trp) c.1163T>G (p.Leu388Trp) n.531T>G c.-42T>G (n.-42T>G) c.1253T>G (p.Leu418Trp) c.1202T>G (p.Leu401Trp) c.1088T>G (p.Leu363Trp) c.1193T>G (p.Leu398Trp) c.1043T>G (p.Leu348Trp) c.935T>G (p.Leu312Trp)
2	g.224503794A>G	CA350827677	CUL3	c.1235T>C (p.Leu412Ser) c.1037T>C (p.Leu346Ser) c.1163T>C (p.Leu388Ser) n.531T>C c.-42T>C (n.-42T>C) c.1253T>C (p.Leu418Ser) c.1202T>C (p.Leu401Ser) c.1088T>C (p.Leu363Ser) c.1193T>C (p.Leu398Ser) c.1043T>C (p.Leu348Ser) c.935T>C (p.Leu312Ser)
2	g.224503794A>T	CA350827679	CUL3	c.1235T>A (p.Leu412Ter) c.1037T>A (p.Leu346Ter) c.1163T>A (p.Leu388Ter) n.531T>A c.-42T>A (n.-42T>A) c.1253T>A (p.Leu418Ter) c.1202T>A (p.Leu401Ter) c.1088T>A (p.Leu363Ter) c.1193T>A (p.Leu398Ter) c.1043T>A (p.Leu348Ter) c.935T>A (p.Leu312Ter)	dbSNP
2	g.224503795A>C	CA350827681	CUL3	c.1234T>G (p.Leu412Val) c.1036T>G (p.Leu346Val) c.1162T>G (p.Leu388Val) n.530T>G c.-43T>G (n.-43T>G) c.1252T>G (p.Leu418Val) c.1201T>G (p.Leu401Val) c.1087T>G (p.Leu363Val) c.1192T>G (p.Leu398Val) c.1042T>G (p.Leu348Val) c.934T>G (p.Leu312Val)
2	g.224503795A>G	CA431492723	CUL3	c.1234T>C (p.Leu412=) c.1036T>C (p.Leu346=) c.1162T>C (p.Leu388=) n.530T>C c.-43T>C (n.-43T>C) c.1252T>C (p.Leu418=) c.1201T>C (p.Leu401=) c.1087T>C (p.Leu363=) c.1192T>C (p.Leu398=) c.1042T>C (p.Leu348=) c.934T>C (p.Leu312=)
2	g.224503795A>T	CA350827683	CUL3	c.1234T>A (p.Leu412Met) c.1036T>A (p.Leu346Met) c.1162T>A (p.Leu388Met) n.530T>A c.-43T>A (n.-43T>A) c.1252T>A (p.Leu418Met) c.1201T>A (p.Leu401Met) c.1087T>A (p.Leu363Met) c.1192T>A (p.Leu398Met) c.1042T>A (p.Leu348Met) c.934T>A (p.Leu312Met)	dbSNP
2	g.224503796T>A	CA431492725	CUL3	c.1233A>T (p.Ile411=) c.1035A>T (p.Ile345=) c.1161A>T (p.Ile387=) n.529A>T c.-44A>T (n.-44A>T) c.1251A>T (p.Ile417=) c.1200A>T (p.Ile400=) c.1086A>T (p.Ile362=) c.1191A>T (p.Ile397=) c.1041A>T (p.Ile347=) c.933A>T (p.Ile311=)	dbSNP
2	g.224503796T>C	CA350827684	CUL3	c.1233A>G (p.Ile411Met) c.1035A>G (p.Ile345Met) c.1161A>G (p.Ile387Met) n.529A>G c.-44A>G (n.-44A>G) c.1251A>G (p.Ile417Met) c.1200A>G (p.Ile400Met) c.1086A>G (p.Ile362Met) c.1191A>G (p.Ile397Met) c.1041A>G (p.Ile347Met) c.933A>G (p.Ile311Met)
2	g.224503796T>G	CA431492724	CUL3	c.1233A>C (p.Ile411=) c.1035A>C (p.Ile345=) c.1161A>C (p.Ile387=) n.529A>C c.-44A>C (n.-44A>C) c.1251A>C (p.Ile417=) c.1200A>C (p.Ile400=) c.1086A>C (p.Ile362=) c.1191A>C (p.Ile397=) c.1041A>C (p.Ile347=) c.933A>C (p.Ile311=)
2	g.224503797A>C	CA350827688	CUL3	c.1232T>G (p.Ile411Arg) c.1034T>G (p.Ile345Arg) c.1160T>G (p.Ile387Arg) n.528T>G c.-45T>G (n.-45T>G) c.1250T>G (p.Ile417Arg) c.1199T>G (p.Ile400Arg) c.1085T>G (p.Ile362Arg) c.1190T>G (p.Ile397Arg) c.1040T>G (p.Ile347Arg) c.932T>G (p.Ile311Arg)
2	g.224503797A>G	CA350827690	CUL3	c.1232T>C (p.Ile411Thr) c.1034T>C (p.Ile345Thr) c.1160T>C (p.Ile387Thr) n.528T>C c.-45T>C (n.-45T>C) c.1250T>C (p.Ile417Thr) c.1199T>C (p.Ile400Thr) c.1085T>C (p.Ile362Thr) c.1190T>C (p.Ile397Thr) c.1040T>C (p.Ile347Thr) c.932T>C (p.Ile311Thr)
2	g.224503797A>T	CA350827686	CUL3	c.1232T>A (p.Ile411Lys) c.1034T>A (p.Ile345Lys) c.1160T>A (p.Ile387Lys) n.528T>A c.-45T>A (n.-45T>A) c.1250T>A (p.Ile417Lys) c.1199T>A (p.Ile400Lys) c.1085T>A (p.Ile362Lys) c.1190T>A (p.Ile397Lys) c.1040T>A (p.Ile347Lys) c.932T>A (p.Ile311Lys)
2	g.224503798T>A	CA350827692	CUL3	c.1231A>T (p.Ile411Leu) c.1033A>T (p.Ile345Leu) c.1159A>T (p.Ile387Leu) n.527A>T c.-46A>T (n.-46A>T) c.1249A>T (p.Ile417Leu) c.1198A>T (p.Ile400Leu) c.1084A>T (p.Ile362Leu) c.1189A>T (p.Ile397Leu) c.1039A>T (p.Ile347Leu) c.931A>T (p.Ile311Leu)	dbSNP
2	g.224503798T>C	CA350827693	CUL3	c.1231A>G (p.Ile411Val) c.1033A>G (p.Ile345Val) c.1159A>G (p.Ile387Val) n.527A>G c.-46A>G (n.-46A>G) c.1249A>G (p.Ile417Val) c.1198A>G (p.Ile400Val) c.1084A>G (p.Ile362Val) c.1189A>G (p.Ile397Val) c.1039A>G (p.Ile347Val) c.931A>G (p.Ile311Val)
2	g.224503798T>G	CA350827694	CUL3	c.1231A>C (p.Ile411Leu) c.1033A>C (p.Ile345Leu) c.1159A>C (p.Ile387Leu) n.527A>C c.-46A>C (n.-46A>C) c.1249A>C (p.Ile417Leu) c.1198A>C (p.Ile400Leu) c.1084A>C (p.Ile362Leu) c.1189A>C (p.Ile397Leu) c.1039A>C (p.Ile347Leu) c.931A>C (p.Ile311Leu)
2	g.224503798_224503799dup	CA2663372490	CUL3	c.1230_1231dup (p.Ile411LysfsTer?) c.1032_1033dup (p.Ile345LysfsTer?) c.1158_1159dup (p.Ile387LysfsTer?) n.526_527dup c.-47_-46dup (n.-47_-46dup) c.1248_1249dup (p.Ile417LysfsTer?) c.1197_1198dup (p.Ile400LysfsTer?) c.1083_1084dup (p.Ile362LysfsTer?) c.1188_1189dup (p.Ile397LysfsTer?) c.1038_1039dup (p.Ile347LysfsTer?) c.930_931dup (p.Ile311LysfsTer?)	gnomAD v4
2	g.224503799T>A	CA431492726	CUL3	c.1230A>T (p.Thr410=) c.1032A>T (p.Thr344=) c.1158A>T (p.Thr386=) n.526A>T c.-47A>T (n.-47A>T) c.1248A>T (p.Thr416=) c.1197A>T (p.Thr399=) c.1083A>T (p.Thr361=) c.1188A>T (p.Thr396=) c.1038A>T (p.Thr346=) c.930A>T (p.Thr310=)
2	g.224503799T>C	CA2140021	CUL3	c.1230A>G (p.Thr410=) c.1032A>G (p.Thr344=) c.1158A>G (p.Thr386=) n.526A>G c.-47A>G (n.-47A>G) c.1248A>G (p.Thr416=) c.1197A>G (p.Thr399=) c.1083A>G (p.Thr361=) c.1188A>G (p.Thr396=) c.1038A>G (p.Thr346=) c.930A>G (p.Thr310=)	dbSNP ExAC gnomAD v2 gnomAD v4
2	g.224503799T>G	CA431492727	CUL3	c.1230A>C (p.Thr410=) c.1032A>C (p.Thr344=) c.1158A>C (p.Thr386=) n.526A>C c.-47A>C (n.-47A>C) c.1248A>C (p.Thr416=) c.1197A>C (p.Thr399=) c.1083A>C (p.Thr361=) c.1188A>C (p.Thr396=) c.1038A>C (p.Thr346=) c.930A>C (p.Thr310=)
2	g.224503799T=	CA1331555958	CUL3	c.1230A= (p.Thr410=) c.1032A= (p.Thr344=) c.1158A= (p.Thr386=) n.526A= c.-47A= (n.-47A=) c.1248A= (p.Thr416=) c.1197A= (p.Thr399=) c.1083A= (p.Thr361=) c.1188A= (p.Thr396=) c.1038A= (p.Thr346=) c.930A= (p.Thr310=)
2	g.224503800G>A	CA2140022	CUL3	c.1229C>T (p.Thr410Ile) c.1031C>T (p.Thr344Ile) c.1157C>T (p.Thr386Ile) n.525C>T c.-48C>T (n.-48C>T) c.1247C>T (p.Thr416Ile) c.1196C>T (p.Thr399Ile) c.1082C>T (p.Thr361Ile) c.1187C>T (p.Thr396Ile) c.1037C>T (p.Thr346Ile) c.929C>T (p.Thr310Ile)	dbSNP ExAC gnomAD v2 gnomAD v4
2	g.224503800G>C	CA350827697	CUL3	c.1229C>G (p.Thr410Arg) c.1031C>G (p.Thr344Arg) c.1157C>G (p.Thr386Arg) n.525C>G c.-48C>G (n.-48C>G) c.1247C>G (p.Thr416Arg) c.1196C>G (p.Thr399Arg) c.1082C>G (p.Thr361Arg) c.1187C>G (p.Thr396Arg) c.1037C>G (p.Thr346Arg) c.929C>G (p.Thr310Arg)	dbSNP
2	g.224503800G=	CA1331555959	CUL3	c.1229C= (p.Thr410=) c.1031C= (p.Thr344=) c.1157C= (p.Thr386=) n.525C= c.-48C= (n.-48C=) c.1247C= (p.Thr416=) c.1196C= (p.Thr399=) c.1082C= (p.Thr361=) c.1187C= (p.Thr396=) c.1037C= (p.Thr346=) c.929C= (p.Thr310=)
2	g.224503800G>T	CA350827699	CUL3	c.1229C>A (p.Thr410Lys) c.1031C>A (p.Thr344Lys) c.1157C>A (p.Thr386Lys) n.525C>A c.-48C>A (n.-48C>A) c.1247C>A (p.Thr416Lys) c.1196C>A (p.Thr399Lys) c.1082C>A (p.Thr361Lys) c.1187C>A (p.Thr396Lys) c.1037C>A (p.Thr346Lys) c.929C>A (p.Thr310Lys)	dbSNP gnomAD v4

Number of alleles fetched