Allele Registry

Chr	Mutation (hg38)	CAid	Gene	Transcript	Linkouts
1	g.154465274_154465275insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC	CA2604852919	IL6R	c.1301_1302insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Ser435AspfsTer25) c.109_110insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (n.109_110insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC) n.499_500insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC c.1065_1066insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Gln356ArgfsTer?) c.142_143insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (n.142_143insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC) c.1349_1350insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Ser451AspfsTer25) c.1448_1449insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Ser484AspfsTer25) c.1400_1401insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Ser468AspfsTer25) c.1394_1395insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Ser466AspfsTer25) c.1295_1296insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Ser433AspfsTer25) c.941_942insAGACCCACCCCAGTGCTTGTTCAGTGCTTGTTCCTCTCATCTCCCCACCGGTGTCCCC (p.Ser315AspfsTer25)	gnomAD v3 gnomAD v4
1	g.154465243C>A	CA342628545	IL6R	c.1270C>A (p.Leu424Ile) c.78C>A (n.78C>A) n.583C>A n.468C>A c.1034C>A (p.Ala345Asp) c.111C>A (n.111C>A) c.1318C>A (p.Leu440Ile) c.1417C>A (p.Leu473Ile) c.1369C>A (p.Leu457Ile) c.1363C>A (p.Leu455Ile) c.1264C>A (p.Leu422Ile) c.910C>A (p.Leu304Ile)
1	g.154465243C=	CA1141952646	IL6R	c.1270C= (p.Leu424=) c.78C= (n.78C=) n.583C= n.468C= c.1034C= (p.Ala345=) c.111C= (n.111C=) c.1318C= (p.Leu440=) c.1417C= (p.Leu473=) c.1369C= (p.Leu457=) c.1363C= (p.Leu455=) c.1264C= (p.Leu422=) c.910C= (p.Leu304=)
1	g.154465243C>G	CA342628546	IL6R	c.1270C>G (p.Leu424Val) c.78C>G (n.78C>G) n.583C>G n.468C>G c.1034C>G (p.Ala345Gly) c.111C>G (n.111C>G) c.1318C>G (p.Leu440Val) c.1417C>G (p.Leu473Val) c.1369C>G (p.Leu457Val) c.1363C>G (p.Leu455Val) c.1264C>G (p.Leu422Val) c.910C>G (p.Leu304Val)
1	g.154465243C>T	CA1129336	IL6R	c.1270C>T (p.Leu424Phe) c.78C>T (n.78C>T) n.583C>T n.468C>T c.1034C>T (p.Ala345Val) c.111C>T (n.111C>T) c.1318C>T (p.Leu440Phe) c.1417C>T (p.Leu473Phe) c.1369C>T (p.Leu457Phe) c.1363C>T (p.Leu455Phe) c.1264C>T (p.Leu422Phe) c.910C>T (p.Leu304Phe)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465244T>A	CA342628547	IL6R	c.1271T>A (p.Leu424His) c.79T>A (n.79T>A) n.584T>A n.469T>A c.1035T>A (p.Ala345=) c.112T>A (n.112T>A) c.1319T>A (p.Leu440His) c.1418T>A (p.Leu473His) c.1370T>A (p.Leu457His) c.1364T>A (p.Leu455His) c.1265T>A (p.Leu422His) c.911T>A (p.Leu304His)
1	g.154465244T>C	CA342628549	IL6R	c.1271T>C (p.Leu424Pro) c.79T>C (n.79T>C) n.584T>C n.469T>C c.1035T>C (p.Ala345=) c.112T>C (n.112T>C) c.1319T>C (p.Leu440Pro) c.1418T>C (p.Leu473Pro) c.1370T>C (p.Leu457Pro) c.1364T>C (p.Leu455Pro) c.1265T>C (p.Leu422Pro) c.911T>C (p.Leu304Pro)
1	g.154465244T>G	CA342628548	IL6R	c.1271T>G (p.Leu424Arg) c.79T>G (n.79T>G) n.584T>G n.469T>G c.1035T>G (p.Ala345=) c.112T>G (n.112T>G) c.1319T>G (p.Leu440Arg) c.1418T>G (p.Leu473Arg) c.1370T>G (p.Leu457Arg) c.1364T>G (p.Leu455Arg) c.1265T>G (p.Leu422Arg) c.911T>G (p.Leu304Arg)
1	g.154465245T>A	CA420975957	IL6R	c.1272T>A (p.Leu424=) c.80T>A (n.80T>A) n.585T>A n.470T>A c.1036T>A (p.Cys346Ser) c.113T>A (n.113T>A) c.1320T>A (p.Leu440=) c.1419T>A (p.Leu473=) c.1371T>A (p.Leu457=) c.1365T>A (p.Leu455=) c.1266T>A (p.Leu422=) c.912T>A (p.Leu304=)
1	g.154465245T>C	CA420975958	IL6R	c.1272T>C (p.Leu424=) c.80T>C (n.80T>C) n.585T>C n.470T>C c.1036T>C (p.Cys346Arg) c.113T>C (n.113T>C) c.1320T>C (p.Leu440=) c.1419T>C (p.Leu473=) c.1371T>C (p.Leu457=) c.1365T>C (p.Leu455=) c.1266T>C (p.Leu422=) c.912T>C (p.Leu304=)
1	g.154465245T>G	CA420975959	IL6R	c.1272T>G (p.Leu424=) c.80T>G (n.80T>G) n.585T>G n.470T>G c.1036T>G (p.Cys346Gly) c.113T>G (n.113T>G) c.1320T>G (p.Leu440=) c.1419T>G (p.Leu473=) c.1371T>G (p.Leu457=) c.1365T>G (p.Leu455=) c.1266T>G (p.Leu422=) c.912T>G (p.Leu304=)
1	g.154465246G>A	CA342628550	IL6R	c.1273G>A (p.Val425Ile) c.81G>A (n.81G>A) n.586G>A n.471G>A c.1037G>A (p.Cys346Tyr) c.114G>A (n.114G>A) c.1321G>A (p.Val441Ile) c.1420G>A (p.Val474Ile) c.1372G>A (p.Val458Ile) c.1366G>A (p.Val456Ile) c.1267G>A (p.Val423Ile) c.913G>A (p.Val305Ile)	dbSNP gnomAD v4
1	g.154465246G>C	CA342628551	IL6R	c.1273G>C (p.Val425Leu) c.81G>C (n.81G>C) n.586G>C n.471G>C c.1037G>C (p.Cys346Ser) c.114G>C (n.114G>C) c.1321G>C (p.Val441Leu) c.1420G>C (p.Val474Leu) c.1372G>C (p.Val458Leu) c.1366G>C (p.Val456Leu) c.1267G>C (p.Val423Leu) c.913G>C (p.Val305Leu)	gnomAD v4
1	g.154465246G=	CA2480880298	IL6R	c.1273G= (p.Val425=) c.81G= (n.81G=) n.586G= n.471G= c.1037G= (p.Cys346=) c.114G= (n.114G=) c.1321G= (p.Val441=) c.1420G= (p.Val474=) c.1372G= (p.Val458=) c.1366G= (p.Val456=) c.1267G= (p.Val423=) c.913G= (p.Val305=)
1	g.154465246G>T	CA342628552	IL6R	c.1273G>T (p.Val425Phe) c.81G>T (n.81G>T) n.586G>T n.471G>T c.1037G>T (p.Cys346Phe) c.114G>T (n.114G>T) c.1321G>T (p.Val441Phe) c.1420G>T (p.Val474Phe) c.1372G>T (p.Val458Phe) c.1366G>T (p.Val456Phe) c.1267G>T (p.Val423Phe) c.913G>T (p.Val305Phe)	dbSNP gnomAD v3 gnomAD v4
1	g.154465247T>A	CA342628553	IL6R	c.1274T>A (p.Val425Asp) c.82T>A (n.82T>A) n.587T>A n.472T>A c.1038T>A (p.Cys346Ter) c.115T>A (n.115T>A) c.1322T>A (p.Val441Asp) c.1421T>A (p.Val474Asp) c.1373T>A (p.Val458Asp) c.1367T>A (p.Val456Asp) c.1268T>A (p.Val423Asp) c.914T>A (p.Val305Asp)
1	g.154465247T>C	CA342628554	IL6R	c.1274T>C (p.Val425Ala) c.82T>C (n.82T>C) n.587T>C n.472T>C c.1038T>C (p.Cys346=) c.115T>C (n.115T>C) c.1322T>C (p.Val441Ala) c.1421T>C (p.Val474Ala) c.1373T>C (p.Val458Ala) c.1367T>C (p.Val456Ala) c.1268T>C (p.Val423Ala) c.914T>C (p.Val305Ala)
1	g.154465247T>G	CA342628555	IL6R	c.1274T>G (p.Val425Gly) c.82T>G (n.82T>G) n.587T>G n.472T>G c.1038T>G (p.Cys346Trp) c.115T>G (n.115T>G) c.1322T>G (p.Val441Gly) c.1421T>G (p.Val474Gly) c.1373T>G (p.Val458Gly) c.1367T>G (p.Val456Gly) c.1268T>G (p.Val423Gly) c.914T>G (p.Val305Gly)
1	g.154465248T>A	CA420975962	IL6R	c.1275T>A (p.Val425=) c.83T>A (n.83T>A) n.588T>A n.473T>A c.1039T>A (p.Ser347Thr) c.116T>A (n.116T>A) c.1323T>A (p.Val441=) c.1422T>A (p.Val474=) c.1374T>A (p.Val458=) c.1368T>A (p.Val456=) c.1269T>A (p.Val423=) c.915T>A (p.Val305=)
1	g.154465248T>C	CA420975963	IL6R	c.1275T>C (p.Val425=) c.83T>C (n.83T>C) n.588T>C n.473T>C c.1039T>C (p.Ser347Pro) c.116T>C (n.116T>C) c.1323T>C (p.Val441=) c.1422T>C (p.Val474=) c.1374T>C (p.Val458=) c.1368T>C (p.Val456=) c.1269T>C (p.Val423=) c.915T>C (p.Val305=)
1	g.154465248T>G	CA420975964	IL6R	c.1275T>G (p.Val425=) c.83T>G (n.83T>G) n.588T>G n.473T>G c.1039T>G (p.Ser347Ala) c.116T>G (n.116T>G) c.1323T>G (p.Val441=) c.1422T>G (p.Val474=) c.1374T>G (p.Val458=) c.1368T>G (p.Val456=) c.1269T>G (p.Val423=) c.915T>G (p.Val305=)
1	g.154465249C>A	CA342628556	IL6R	c.1276C>A (p.Pro426Thr) c.84C>A (n.84C>A) n.474C>A c.1040C>A (p.Ser347Tyr) c.117C>A (n.117C>A) c.1324C>A (p.Pro442Thr) c.1423C>A (p.Pro475Thr) c.1375C>A (p.Pro459Thr) c.1369C>A (p.Pro457Thr) c.1270C>A (p.Pro424Thr) c.916C>A (p.Pro306Thr)
1	g.154465249C>G	CA342628557	IL6R	c.1276C>G (p.Pro426Ala) c.84C>G (n.84C>G) n.474C>G c.1040C>G (p.Ser347Cys) c.117C>G (n.117C>G) c.1324C>G (p.Pro442Ala) c.1423C>G (p.Pro475Ala) c.1375C>G (p.Pro459Ala) c.1369C>G (p.Pro457Ala) c.1270C>G (p.Pro424Ala) c.916C>G (p.Pro306Ala)
1	g.154465249C>T	CA342628558	IL6R	c.1276C>T (p.Pro426Ser) c.84C>T (n.84C>T) n.474C>T c.1040C>T (p.Ser347Phe) c.117C>T (n.117C>T) c.1324C>T (p.Pro442Ser) c.1423C>T (p.Pro475Ser) c.1375C>T (p.Pro459Ser) c.1369C>T (p.Pro457Ser) c.1270C>T (p.Pro424Ser) c.916C>T (p.Pro306Ser)
1	g.154465250C>A	CA342628560	IL6R	c.1277C>A (p.Pro426His) c.85C>A (n.85C>A) n.475C>A c.1041C>A (p.Ser347=) c.118C>A (n.118C>A) c.1325C>A (p.Pro442His) c.1424C>A (p.Pro475His) c.1376C>A (p.Pro459His) c.1370C>A (p.Pro457His) c.1271C>A (p.Pro424His) c.917C>A (p.Pro306His)
1	g.154465250C>G	CA342628561	IL6R	c.1277C>G (p.Pro426Arg) c.85C>G (n.85C>G) n.475C>G c.1041C>G (p.Ser347=) c.118C>G (n.118C>G) c.1325C>G (p.Pro442Arg) c.1424C>G (p.Pro475Arg) c.1376C>G (p.Pro459Arg) c.1370C>G (p.Pro457Arg) c.1271C>G (p.Pro424Arg) c.917C>G (p.Pro306Arg)
1	g.154465250C>T	CA342628559	IL6R	c.1277C>T (p.Pro426Leu) c.85C>T (n.85C>T) n.475C>T c.1041C>T (p.Ser347=) c.118C>T (n.118C>T) c.1325C>T (p.Pro442Leu) c.1424C>T (p.Pro475Leu) c.1376C>T (p.Pro459Leu) c.1370C>T (p.Pro457Leu) c.1271C>T (p.Pro424Leu) c.917C>T (p.Pro306Leu)	gnomAD v4
1	g.154465251T>A	CA420975965	IL6R	c.1278T>A (p.Pro426=) c.86T>A (n.86T>A) n.476T>A c.1042T>A (p.Ser348Thr) c.119T>A (n.119T>A) c.1326T>A (p.Pro442=) c.1425T>A (p.Pro475=) c.1377T>A (p.Pro459=) c.1371T>A (p.Pro457=) c.1272T>A (p.Pro424=) c.918T>A (p.Pro306=)
1	g.154465251T>C	CA420975966	IL6R	c.1278T>C (p.Pro426=) c.86T>C (n.86T>C) n.476T>C c.1042T>C (p.Ser348Pro) c.119T>C (n.119T>C) c.1326T>C (p.Pro442=) c.1425T>C (p.Pro475=) c.1377T>C (p.Pro459=) c.1371T>C (p.Pro457=) c.1272T>C (p.Pro424=) c.918T>C (p.Pro306=)
1	g.154465251T>G	CA420975967	IL6R	c.1278T>G (p.Pro426=) c.86T>G (n.86T>G) n.476T>G c.1042T>G (p.Ser348Ala) c.119T>G (n.119T>G) c.1326T>G (p.Pro442=) c.1425T>G (p.Pro475=) c.1377T>G (p.Pro459=) c.1371T>G (p.Pro457=) c.1272T>G (p.Pro424=) c.918T>G (p.Pro306=)
1	g.154465252C>A	CA342628562	IL6R	c.1279C>A (p.Leu427Ile) c.87C>A (n.87C>A) n.477C>A c.1043C>A (p.Ser348Tyr) c.120C>A (n.120C>A) c.1327C>A (p.Leu443Ile) c.1426C>A (p.Leu476Ile) c.1378C>A (p.Leu460Ile) c.1372C>A (p.Leu458Ile) c.1273C>A (p.Leu425Ile) c.919C>A (p.Leu307Ile)
1	g.154465252C>G	CA342628563	IL6R	c.1279C>G (p.Leu427Val) c.87C>G (n.87C>G) n.477C>G c.1043C>G (p.Ser348Cys) c.120C>G (n.120C>G) c.1327C>G (p.Leu443Val) c.1426C>G (p.Leu476Val) c.1378C>G (p.Leu460Val) c.1372C>G (p.Leu458Val) c.1273C>G (p.Leu425Val) c.919C>G (p.Leu307Val)	gnomAD v4
1	g.154465252C>T	CA342628564	IL6R	c.1279C>T (p.Leu427Phe) c.87C>T (n.87C>T) n.477C>T c.1043C>T (p.Ser348Phe) c.120C>T (n.120C>T) c.1327C>T (p.Leu443Phe) c.1426C>T (p.Leu476Phe) c.1378C>T (p.Leu460Phe) c.1372C>T (p.Leu458Phe) c.1273C>T (p.Leu425Phe) c.919C>T (p.Leu307Phe)	gnomAD v4
1	g.154465253T>A	CA342628565	IL6R	c.1280T>A (p.Leu427His) c.88T>A (n.88T>A) n.478T>A c.1044T>A (p.Ser348=) c.121T>A (n.121T>A) c.1328T>A (p.Leu443His) c.1427T>A (p.Leu476His) c.1379T>A (p.Leu460His) c.1373T>A (p.Leu458His) c.1274T>A (p.Leu425His) c.920T>A (p.Leu307His)
1	g.154465253T>C	CA342628566	IL6R	c.1280T>C (p.Leu427Pro) c.88T>C (n.88T>C) n.478T>C c.1044T>C (p.Ser348=) c.121T>C (n.121T>C) c.1328T>C (p.Leu443Pro) c.1427T>C (p.Leu476Pro) c.1379T>C (p.Leu460Pro) c.1373T>C (p.Leu458Pro) c.1274T>C (p.Leu425Pro) c.920T>C (p.Leu307Pro)
1	g.154465253T>G	CA342628567	IL6R	c.1280T>G (p.Leu427Arg) c.88T>G (n.88T>G) n.478T>G c.1044T>G (p.Ser348=) c.121T>G (n.121T>G) c.1328T>G (p.Leu443Arg) c.1427T>G (p.Leu476Arg) c.1379T>G (p.Leu460Arg) c.1373T>G (p.Leu458Arg) c.1274T>G (p.Leu425Arg) c.920T>G (p.Leu307Arg)
1	g.154465254C>A	CA420975968	IL6R	c.1281C>A (p.Leu427=) c.89C>A (n.89C>A) n.479C>A c.1045C>A (p.His349Asn) c.122C>A (n.122C>A) c.1329C>A (p.Leu443=) c.1428C>A (p.Leu476=) c.1380C>A (p.Leu460=) c.1374C>A (p.Leu458=) c.1275C>A (p.Leu425=) c.921C>A (p.Leu307=)	dbSNP
1	g.154465254C=	CA2480880299	IL6R	c.1281C= (p.Leu427=) c.89C= (n.89C=) n.479C= c.1045C= (p.His349=) c.122C= (n.122C=) c.1329C= (p.Leu443=) c.1428C= (p.Leu476=) c.1380C= (p.Leu460=) c.1374C= (p.Leu458=) c.1275C= (p.Leu425=) c.921C= (p.Leu307=)
1	g.154465254C>G	CA420975970	IL6R	c.1281C>G (p.Leu427=) c.89C>G (n.89C>G) n.479C>G c.1045C>G (p.His349Asp) c.122C>G (n.122C>G) c.1329C>G (p.Leu443=) c.1428C>G (p.Leu476=) c.1380C>G (p.Leu460=) c.1374C>G (p.Leu458=) c.1275C>G (p.Leu425=) c.921C>G (p.Leu307=)
1	g.154465254C>T	CA420975969	IL6R	c.1281C>T (p.Leu427=) c.89C>T (n.89C>T) n.479C>T c.1045C>T (p.His349Tyr) c.122C>T (n.122C>T) c.1329C>T (p.Leu443=) c.1428C>T (p.Leu476=) c.1380C>T (p.Leu460=) c.1374C>T (p.Leu458=) c.1275C>T (p.Leu425=) c.921C>T (p.Leu307=)	gnomAD v4
1	g.154465255A>C	CA342628568	IL6R	c.1282A>C (p.Ile428Leu) c.90A>C (n.90A>C) n.480A>C c.1046A>C (p.His349Pro) c.123A>C (n.123A>C) c.1330A>C (p.Ile444Leu) c.1429A>C (p.Ile477Leu) c.1381A>C (p.Ile461Leu) c.1375A>C (p.Ile459Leu) c.1276A>C (p.Ile426Leu) c.922A>C (p.Ile308Leu)
1	g.154465255A>G	CA342628569	IL6R	c.1282A>G (p.Ile428Val) c.90A>G (n.90A>G) n.480A>G c.1046A>G (p.His349Arg) c.123A>G (n.123A>G) c.1330A>G (p.Ile444Val) c.1429A>G (p.Ile477Val) c.1381A>G (p.Ile461Val) c.1375A>G (p.Ile459Val) c.1276A>G (p.Ile426Val) c.922A>G (p.Ile308Val)
1	g.154465255A>T	CA342628570	IL6R	c.1282A>T (p.Ile428Phe) c.90A>T (n.90A>T) n.480A>T c.1046A>T (p.His349Leu) c.123A>T (n.123A>T) c.1330A>T (p.Ile444Phe) c.1429A>T (p.Ile477Phe) c.1381A>T (p.Ile461Phe) c.1375A>T (p.Ile459Phe) c.1276A>T (p.Ile426Phe) c.922A>T (p.Ile308Phe)	gnomAD v4
1	g.154465256T>A	CA342628571	IL6R	c.1283T>A (p.Ile428Asn) c.91T>A (n.91T>A) n.481T>A c.1047T>A (p.His349Gln) c.124T>A (n.124T>A) c.1331T>A (p.Ile444Asn) c.1430T>A (p.Ile477Asn) c.1382T>A (p.Ile461Asn) c.1376T>A (p.Ile459Asn) c.1277T>A (p.Ile426Asn) c.923T>A (p.Ile308Asn)
1	g.154465256T>C	CA1129337	IL6R	c.1283T>C (p.Ile428Thr) c.91T>C (n.91T>C) n.481T>C c.1047T>C (p.His349=) c.124T>C (n.124T>C) c.1331T>C (p.Ile444Thr) c.1430T>C (p.Ile477Thr) c.1382T>C (p.Ile461Thr) c.1376T>C (p.Ile459Thr) c.1277T>C (p.Ile426Thr) c.923T>C (p.Ile308Thr)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465256T>G	CA342628572	IL6R	c.1283T>G (p.Ile428Ser) c.91T>G (n.91T>G) n.481T>G c.1047T>G (p.His349Gln) c.124T>G (n.124T>G) c.1331T>G (p.Ile444Ser) c.1430T>G (p.Ile477Ser) c.1382T>G (p.Ile461Ser) c.1376T>G (p.Ile459Ser) c.1277T>G (p.Ile426Ser) c.923T>G (p.Ile308Ser)
1	g.154465256T=	CA2480880300	IL6R	c.1283T= (p.Ile428=) c.91T= (n.91T=) n.481T= c.1047T= (p.His349=) c.124T= (n.124T=) c.1331T= (p.Ile444=) c.1430T= (p.Ile477=) c.1382T= (p.Ile461=) c.1376T= (p.Ile459=) c.1277T= (p.Ile426=) c.923T= (p.Ile308=)
1	g.154465257C>A	CA420975971	IL6R	c.1284C>A (p.Ile428=) c.92C>A (n.92C>A) n.482C>A c.1048C>A (p.Leu350Ile) c.125C>A (n.125C>A) c.1332C>A (p.Ile444=) c.1431C>A (p.Ile477=) c.1383C>A (p.Ile461=) c.1377C>A (p.Ile459=) c.1278C>A (p.Ile426=) c.924C>A (p.Ile308=)
1	g.154465257C=	CA2480880301	IL6R	c.1284C= (p.Ile428=) c.92C= (n.92C=) n.482C= c.1048C= (p.Leu350=) c.125C= (n.125C=) c.1332C= (p.Ile444=) c.1431C= (p.Ile477=) c.1383C= (p.Ile461=) c.1377C= (p.Ile459=) c.1278C= (p.Ile426=) c.924C= (p.Ile308=)
1	g.154465257C>G	CA342628573	IL6R	c.1284C>G (p.Ile428Met) c.92C>G (n.92C>G) n.482C>G c.1048C>G (p.Leu350Val) c.125C>G (n.125C>G) c.1332C>G (p.Ile444Met) c.1431C>G (p.Ile477Met) c.1383C>G (p.Ile461Met) c.1377C>G (p.Ile459Met) c.1278C>G (p.Ile426Met) c.924C>G (p.Ile308Met)	dbSNP gnomAD v2 gnomAD v4
1	g.154465257C>T	CA420975972	IL6R	c.1284C>T (p.Ile428=) c.92C>T (n.92C>T) n.482C>T c.1048C>T (p.Leu350Phe) c.125C>T (n.125C>T) c.1332C>T (p.Ile444=) c.1431C>T (p.Ile477=) c.1383C>T (p.Ile461=) c.1377C>T (p.Ile459=) c.1278C>T (p.Ile426=) c.924C>T (p.Ile308=)	gnomAD v4
1	g.154465258T>A	CA342628576	IL6R	c.1285T>A (p.Ser429Thr) c.93T>A (n.93T>A) n.483T>A c.1049T>A (p.Leu350His) c.126T>A (n.126T>A) c.1333T>A (p.Ser445Thr) c.1432T>A (p.Ser478Thr) c.1384T>A (p.Ser462Thr) c.1378T>A (p.Ser460Thr) c.1279T>A (p.Ser427Thr) c.925T>A (p.Ser309Thr)
1	g.154465258T>C	CA342628575	IL6R	c.1285T>C (p.Ser429Pro) c.93T>C (n.93T>C) n.483T>C c.1049T>C (p.Leu350Pro) c.126T>C (n.126T>C) c.1333T>C (p.Ser445Pro) c.1432T>C (p.Ser478Pro) c.1384T>C (p.Ser462Pro) c.1378T>C (p.Ser460Pro) c.1279T>C (p.Ser427Pro) c.925T>C (p.Ser309Pro)
1	g.154465258T>G	CA342628574	IL6R	c.1285T>G (p.Ser429Ala) c.93T>G (n.93T>G) n.483T>G c.1049T>G (p.Leu350Arg) c.126T>G (n.126T>G) c.1333T>G (p.Ser445Ala) c.1432T>G (p.Ser478Ala) c.1384T>G (p.Ser462Ala) c.1378T>G (p.Ser460Ala) c.1279T>G (p.Ser427Ala) c.925T>G (p.Ser309Ala)
1	g.154465259C>A	CA342628577	IL6R	c.1286C>A (p.Ser429Tyr) c.94C>A (n.94C>A) n.484C>A c.1050C>A (p.Leu350=) c.127C>A (n.127C>A) c.1334C>A (p.Ser445Tyr) c.1433C>A (p.Ser478Tyr) c.1385C>A (p.Ser462Tyr) c.1379C>A (p.Ser460Tyr) c.1280C>A (p.Ser427Tyr) c.926C>A (p.Ser309Tyr)
1	g.154465259C>G	CA342628578	IL6R	c.1286C>G (p.Ser429Cys) c.94C>G (n.94C>G) n.484C>G c.1050C>G (p.Leu350=) c.127C>G (n.127C>G) c.1334C>G (p.Ser445Cys) c.1433C>G (p.Ser478Cys) c.1385C>G (p.Ser462Cys) c.1379C>G (p.Ser460Cys) c.1280C>G (p.Ser427Cys) c.926C>G (p.Ser309Cys)
1	g.154465259C>T	CA342628579	IL6R	c.1286C>T (p.Ser429Phe) c.94C>T (n.94C>T) n.484C>T c.1050C>T (p.Leu350=) c.127C>T (n.127C>T) c.1334C>T (p.Ser445Phe) c.1433C>T (p.Ser478Phe) c.1385C>T (p.Ser462Phe) c.1379C>T (p.Ser460Phe) c.1280C>T (p.Ser427Phe) c.926C>T (p.Ser309Phe)	gnomAD v4 COSMIC
1	g.154465260C>A	CA420975973	IL6R	c.1287C>A (p.Ser429=) c.95C>A (n.95C>A) n.485C>A c.1051C>A (p.Pro351Thr) c.128C>A (n.128C>A) c.1335C>A (p.Ser445=) c.1434C>A (p.Ser478=) c.1386C>A (p.Ser462=) c.1380C>A (p.Ser460=) c.1281C>A (p.Ser427=) c.927C>A (p.Ser309=)
1	g.154465260C>G	CA420975974	IL6R	c.1287C>G (p.Ser429=) c.95C>G (n.95C>G) n.485C>G c.1051C>G (p.Pro351Ala) c.128C>G (n.128C>G) c.1335C>G (p.Ser445=) c.1434C>G (p.Ser478=) c.1386C>G (p.Ser462=) c.1380C>G (p.Ser460=) c.1281C>G (p.Ser427=) c.927C>G (p.Ser309=)
1	g.154465260C>T	CA420975975	IL6R	c.1287C>T (p.Ser429=) c.95C>T (n.95C>T) n.485C>T c.1051C>T (p.Pro351Ser) c.128C>T (n.128C>T) c.1335C>T (p.Ser445=) c.1434C>T (p.Ser478=) c.1386C>T (p.Ser462=) c.1380C>T (p.Ser460=) c.1281C>T (p.Ser427=) c.927C>T (p.Ser309=)
1	g.154465261C>A	CA342628580	IL6R	c.1288C>A (p.Pro430Thr) c.96C>A (n.96C>A) n.486C>A c.1052C>A (p.Pro351His) c.129C>A (n.129C>A) c.1336C>A (p.Pro446Thr) c.1435C>A (p.Pro479Thr) c.1387C>A (p.Pro463Thr) c.1381C>A (p.Pro461Thr) c.1282C>A (p.Pro428Thr) c.928C>A (p.Pro310Thr)
1	g.154465261C>G	CA342628581	IL6R	c.1288C>G (p.Pro430Ala) c.96C>G (n.96C>G) n.486C>G c.1052C>G (p.Pro351Arg) c.129C>G (n.129C>G) c.1336C>G (p.Pro446Ala) c.1435C>G (p.Pro479Ala) c.1387C>G (p.Pro463Ala) c.1381C>G (p.Pro461Ala) c.1282C>G (p.Pro428Ala) c.928C>G (p.Pro310Ala)
1	g.154465261C>T	CA342628582	IL6R	c.1288C>T (p.Pro430Ser) c.96C>T (n.96C>T) n.486C>T c.1052C>T (p.Pro351Leu) c.129C>T (n.129C>T) c.1336C>T (p.Pro446Ser) c.1435C>T (p.Pro479Ser) c.1387C>T (p.Pro463Ser) c.1381C>T (p.Pro461Ser) c.1282C>T (p.Pro428Ser) c.928C>T (p.Pro310Ser)
1	g.154465262C>A	CA342628583	IL6R	c.1289C>A (p.Pro430Gln) c.97C>A (n.97C>A) n.487C>A c.1053C>A (p.Pro351=) c.130C>A (n.130C>A) c.1337C>A (p.Pro446Gln) c.1436C>A (p.Pro479Gln) c.1388C>A (p.Pro463Gln) c.1382C>A (p.Pro461Gln) c.1283C>A (p.Pro428Gln) c.929C>A (p.Pro310Gln)
1	g.154465262C>G	CA342628584	IL6R	c.1289C>G (p.Pro430Arg) c.97C>G (n.97C>G) n.487C>G c.1053C>G (p.Pro351=) c.130C>G (n.130C>G) c.1337C>G (p.Pro446Arg) c.1436C>G (p.Pro479Arg) c.1388C>G (p.Pro463Arg) c.1382C>G (p.Pro461Arg) c.1283C>G (p.Pro428Arg) c.929C>G (p.Pro310Arg)
1	g.154465262C>T	CA342628585	IL6R	c.1289C>T (p.Pro430Leu) c.97C>T (n.97C>T) n.487C>T c.1053C>T (p.Pro351=) c.130C>T (n.130C>T) c.1337C>T (p.Pro446Leu) c.1436C>T (p.Pro479Leu) c.1388C>T (p.Pro463Leu) c.1382C>T (p.Pro461Leu) c.1283C>T (p.Pro428Leu) c.929C>T (p.Pro310Leu)
1	g.154465263A>C	CA420975976	IL6R	c.1290A>C (p.Pro430=) c.98A>C (n.98A>C) n.488A>C c.1054A>C (p.Thr352Pro) c.131A>C (n.131A>C) c.1338A>C (p.Pro446=) c.1437A>C (p.Pro479=) c.1389A>C (p.Pro463=) c.1383A>C (p.Pro461=) c.1284A>C (p.Pro428=) c.930A>C (p.Pro310=)
1	g.154465263A>G	CA420975977	IL6R	c.1290A>G (p.Pro430=) c.98A>G (n.98A>G) n.488A>G c.1054A>G (p.Thr352Ala) c.131A>G (n.131A>G) c.1338A>G (p.Pro446=) c.1437A>G (p.Pro479=) c.1389A>G (p.Pro463=) c.1383A>G (p.Pro461=) c.1284A>G (p.Pro428=) c.930A>G (p.Pro310=)
1	g.154465263A>T	CA420975978	IL6R	c.1290A>T (p.Pro430=) c.98A>T (n.98A>T) n.488A>T c.1054A>T (p.Thr352Ser) c.131A>T (n.131A>T) c.1338A>T (p.Pro446=) c.1437A>T (p.Pro479=) c.1389A>T (p.Pro463=) c.1383A>T (p.Pro461=) c.1284A>T (p.Pro428=) c.930A>T (p.Pro310=)
1	g.154465263_154465273delinsACCGGTGTCCC	CA2480880302	IL6R	c.1290_1300delinsACCGGTGTCCC (p.Pro430=) c.98_108delinsACCGGTGTCCC (n.98_108delinsACCGGTGTCCC) n.488_498delinsACCGGTGTCCC c.1054_1064delinsACCGGTGTCCC (p.Thr352=) c.131_141delinsACCGGTGTCCC (n.131_141delinsACCGGTGTCCC) c.1338_1348delinsACCGGTGTCCC (p.Pro446=) c.1437_1447delinsACCGGTGTCCC (p.Pro479=) c.1389_1399delinsACCGGTGTCCC (p.Pro463=) c.1383_1393delinsACCGGTGTCCC (p.Pro461=) c.1284_1294delinsACCGGTGTCCC (p.Pro428=) c.930_940delinsACCGGTGTCCC (p.Pro310=)
1	g.154465264C>A	CA342628586	IL6R	c.1291C>A (p.Pro431Thr) c.99C>A (n.99C>A) n.489C>A c.1055C>A (p.Thr352Asn) c.132C>A (n.132C>A) c.1339C>A (p.Pro447Thr) c.1438C>A (p.Pro480Thr) c.1390C>A (p.Pro464Thr) c.1384C>A (p.Pro462Thr) c.1285C>A (p.Pro429Thr) c.931C>A (p.Pro311Thr)
1	g.154465264C=	CA2480880303	IL6R	c.1291C= (p.Pro431=) c.99C= (n.99C=) n.489C= c.1055C= (p.Thr352=) c.132C= (n.132C=) c.1339C= (p.Pro447=) c.1438C= (p.Pro480=) c.1390C= (p.Pro464=) c.1384C= (p.Pro462=) c.1285C= (p.Pro429=) c.931C= (p.Pro311=)
1	g.154465264C>G	CA342628587	IL6R	c.1291C>G (p.Pro431Ala) c.99C>G (n.99C>G) n.489C>G c.1055C>G (p.Thr352Ser) c.132C>G (n.132C>G) c.1339C>G (p.Pro447Ala) c.1438C>G (p.Pro480Ala) c.1390C>G (p.Pro464Ala) c.1384C>G (p.Pro462Ala) c.1285C>G (p.Pro429Ala) c.931C>G (p.Pro311Ala)
1	g.154465264C>T	CA342628588	IL6R	c.1291C>T (p.Pro431Ser) c.99C>T (n.99C>T) n.489C>T c.1055C>T (p.Thr352Ile) c.132C>T (n.132C>T) c.1339C>T (p.Pro447Ser) c.1438C>T (p.Pro480Ser) c.1390C>T (p.Pro464Ser) c.1384C>T (p.Pro462Ser) c.1285C>T (p.Pro429Ser) c.931C>T (p.Pro311Ser)	ClinVar dbSNP
1	g.154465266_154465275del	CA1129338	IL6R	c.1293_1302del (p.Val432AlafsTer?) c.101_110del (n.101_110del) n.491_500del c.1057_1066del (p.Gly353SerfsTer?) c.134_143del (n.134_143del) c.1341_1350del (p.Val448AlafsTer?) c.1440_1449del (p.Val481AlafsTer?) c.1392_1401del (p.Val465AlafsTer?) c.1386_1395del (p.Val463AlafsTer?) c.1287_1296del (p.Val430AlafsTer?) c.933_942del (p.Val312AlafsTer?)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465265C>A	CA342628589	IL6R	c.1292C>A (p.Pro431Gln) c.100C>A (n.100C>A) n.490C>A c.1056C>A (p.Thr352=) c.133C>A (n.133C>A) c.1340C>A (p.Pro447Gln) c.1439C>A (p.Pro480Gln) c.1391C>A (p.Pro464Gln) c.1385C>A (p.Pro462Gln) c.1286C>A (p.Pro429Gln) c.932C>A (p.Pro311Gln)
1	g.154465265C=	CA1143366893	IL6R	c.1292C= (p.Pro431=) c.100C= (n.100C=) n.490C= c.1056C= (p.Thr352=) c.133C= (n.133C=) c.1340C= (p.Pro447=) c.1439C= (p.Pro480=) c.1391C= (p.Pro464=) c.1385C= (p.Pro462=) c.1286C= (p.Pro429=) c.932C= (p.Pro311=)
1	g.154465265C>G	CA342628590	IL6R	c.1292C>G (p.Pro431Arg) c.100C>G (n.100C>G) n.490C>G c.1056C>G (p.Thr352=) c.133C>G (n.133C>G) c.1340C>G (p.Pro447Arg) c.1439C>G (p.Pro480Arg) c.1391C>G (p.Pro464Arg) c.1385C>G (p.Pro462Arg) c.1286C>G (p.Pro429Arg) c.932C>G (p.Pro311Arg)	dbSNP
1	g.154465265C>T	CA1129339	IL6R	c.1292C>T (p.Pro431Leu) c.100C>T (n.100C>T) n.490C>T c.1056C>T (p.Thr352=) c.133C>T (n.133C>T) c.1340C>T (p.Pro447Leu) c.1439C>T (p.Pro480Leu) c.1391C>T (p.Pro464Leu) c.1385C>T (p.Pro462Leu) c.1286C>T (p.Pro429Leu) c.932C>T (p.Pro311Leu)	dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465266G>A	CA30816507	IL6R	c.1293G>A (p.Pro431=) c.101G>A (n.101G>A) n.491G>A c.1057G>A (p.Gly353Ser) c.134G>A (n.134G>A) c.1341G>A (p.Pro447=) c.1440G>A (p.Pro480=) c.1392G>A (p.Pro464=) c.1386G>A (p.Pro462=) c.1287G>A (p.Pro429=) c.933G>A (p.Pro311=)	ClinVar dbSNP gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465266G>C	CA420975980	IL6R	c.1293G>C (p.Pro431=) c.101G>C (n.101G>C) n.491G>C c.1057G>C (p.Gly353Arg) c.134G>C (n.134G>C) c.1341G>C (p.Pro447=) c.1440G>C (p.Pro480=) c.1392G>C (p.Pro464=) c.1386G>C (p.Pro462=) c.1287G>C (p.Pro429=) c.933G>C (p.Pro311=)	dbSNP gnomAD v2 gnomAD v4
1	g.154465266G=	CA2480880304	IL6R	c.1293G= (p.Pro431=) c.101G= (n.101G=) n.491G= c.1057G= (p.Gly353=) c.134G= (n.134G=) c.1341G= (p.Pro447=) c.1440G= (p.Pro480=) c.1392G= (p.Pro464=) c.1386G= (p.Pro462=) c.1287G= (p.Pro429=) c.933G= (p.Pro311=)
1	g.154465266G>T	CA420975979	IL6R	c.1293G>T (p.Pro431=) c.101G>T (n.101G>T) n.491G>T c.1057G>T (p.Gly353Cys) c.134G>T (n.134G>T) c.1341G>T (p.Pro447=) c.1440G>T (p.Pro480=) c.1392G>T (p.Pro464=) c.1386G>T (p.Pro462=) c.1287G>T (p.Pro429=) c.933G>T (p.Pro311=)
1	g.154465267G>A	CA342628592	IL6R	c.1294G>A (p.Val432Met) c.102G>A (n.102G>A) n.492G>A c.1058G>A (p.Gly353Asp) c.135G>A (n.135G>A) c.1342G>A (p.Val448Met) c.1441G>A (p.Val481Met) c.1393G>A (p.Val465Met) c.1387G>A (p.Val463Met) c.1288G>A (p.Val430Met) c.934G>A (p.Val312Met)
1	g.154465267G>C	CA342628591	IL6R	c.1294G>C (p.Val432Leu) c.102G>C (n.102G>C) n.492G>C c.1058G>C (p.Gly353Ala) c.135G>C (n.135G>C) c.1342G>C (p.Val448Leu) c.1441G>C (p.Val481Leu) c.1393G>C (p.Val465Leu) c.1387G>C (p.Val463Leu) c.1288G>C (p.Val430Leu) c.934G>C (p.Val312Leu)	dbSNP
1	g.154465267G=	CA2480880305	IL6R	c.1294G= (p.Val432=) c.102G= (n.102G=) n.492G= c.1058G= (p.Gly353=) c.135G= (n.135G=) c.1342G= (p.Val448=) c.1441G= (p.Val481=) c.1393G= (p.Val465=) c.1387G= (p.Val463=) c.1288G= (p.Val430=) c.934G= (p.Val312=)
1	g.154465267G>T	CA342628593	IL6R	c.1294G>T (p.Val432Leu) c.102G>T (n.102G>T) n.492G>T c.1058G>T (p.Gly353Val) c.135G>T (n.135G>T) c.1342G>T (p.Val448Leu) c.1441G>T (p.Val481Leu) c.1393G>T (p.Val465Leu) c.1387G>T (p.Val463Leu) c.1288G>T (p.Val430Leu) c.934G>T (p.Val312Leu)
1	g.154465268T>A	CA342628594	IL6R	c.1295T>A (p.Val432Glu) c.103T>A (n.103T>A) n.493T>A c.1059T>A (p.Gly353=) c.136T>A (n.136T>A) c.1343T>A (p.Val448Glu) c.1442T>A (p.Val481Glu) c.1394T>A (p.Val465Glu) c.1388T>A (p.Val463Glu) c.1289T>A (p.Val430Glu) c.935T>A (p.Val312Glu)
1	g.154465268T>C	CA1129340	IL6R	c.1295T>C (p.Val432Ala) c.103T>C (n.103T>C) n.493T>C c.1059T>C (p.Gly353=) c.136T>C (n.136T>C) c.1343T>C (p.Val448Ala) c.1442T>C (p.Val481Ala) c.1394T>C (p.Val465Ala) c.1388T>C (p.Val463Ala) c.1289T>C (p.Val430Ala) c.935T>C (p.Val312Ala)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465268T>G	CA342628595	IL6R	c.1295T>G (p.Val432Gly) c.103T>G (n.103T>G) n.493T>G c.1059T>G (p.Gly353=) c.136T>G (n.136T>G) c.1343T>G (p.Val448Gly) c.1442T>G (p.Val481Gly) c.1394T>G (p.Val465Gly) c.1388T>G (p.Val463Gly) c.1289T>G (p.Val430Gly) c.935T>G (p.Val312Gly)
1	g.154465268T=	CA2480880306	IL6R	c.1295T= (p.Val432=) c.103T= (n.103T=) n.493T= c.1059T= (p.Gly353=) c.136T= (n.136T=) c.1343T= (p.Val448=) c.1442T= (p.Val481=) c.1394T= (p.Val465=) c.1388T= (p.Val463=) c.1289T= (p.Val430=) c.935T= (p.Val312=)
1	g.154465269G>A	CA420975982	IL6R	c.1296G>A (p.Val432=) c.104G>A (n.104G>A) n.494G>A c.1060G>A (p.Val354Ile) c.137G>A (n.137G>A) c.1344G>A (p.Val448=) c.1443G>A (p.Val481=) c.1395G>A (p.Val465=) c.1389G>A (p.Val463=) c.1290G>A (p.Val430=) c.936G>A (p.Val312=)	gnomAD v4
1	g.154465269G>C	CA420975983	IL6R	c.1296G>C (p.Val432=) c.104G>C (n.104G>C) n.494G>C c.1060G>C (p.Val354Leu) c.137G>C (n.137G>C) c.1344G>C (p.Val448=) c.1443G>C (p.Val481=) c.1395G>C (p.Val465=) c.1389G>C (p.Val463=) c.1290G>C (p.Val430=) c.936G>C (p.Val312=)
1	g.154465269G>T	CA420975984	IL6R	c.1296G>T (p.Val432=) c.104G>T (n.104G>T) n.494G>T c.1060G>T (p.Val354Phe) c.137G>T (n.137G>T) c.1344G>T (p.Val448=) c.1443G>T (p.Val481=) c.1395G>T (p.Val465=) c.1389G>T (p.Val463=) c.1290G>T (p.Val430=) c.936G>T (p.Val312=)	gnomAD v4
1	g.154465270T>A	CA342628596	IL6R	c.1297T>A (p.Ser433Thr) c.105T>A (n.105T>A) n.495T>A c.1061T>A (p.Val354Asp) c.138T>A (n.138T>A) c.1345T>A (p.Ser449Thr) c.1444T>A (p.Ser482Thr) c.1396T>A (p.Ser466Thr) c.1390T>A (p.Ser464Thr) c.1291T>A (p.Ser431Thr) c.937T>A (p.Ser313Thr)
1	g.154465270T>C	CA30816512	IL6R	c.1297T>C (p.Ser433Pro) c.105T>C (n.105T>C) n.495T>C c.1061T>C (p.Val354Ala) c.138T>C (n.138T>C) c.1345T>C (p.Ser449Pro) c.1444T>C (p.Ser482Pro) c.1396T>C (p.Ser466Pro) c.1390T>C (p.Ser464Pro) c.1291T>C (p.Ser431Pro) c.937T>C (p.Ser313Pro)	dbSNP gnomAD v4
1	g.154465270T>G	CA342628597	IL6R	c.1297T>G (p.Ser433Ala) c.105T>G (n.105T>G) n.495T>G c.1061T>G (p.Val354Gly) c.138T>G (n.138T>G) c.1345T>G (p.Ser449Ala) c.1444T>G (p.Ser482Ala) c.1396T>G (p.Ser466Ala) c.1390T>G (p.Ser464Ala) c.1291T>G (p.Ser431Ala) c.937T>G (p.Ser313Ala)
1	g.154465270T=	CA2480880308	IL6R	c.1297T= (p.Ser433=) c.105T= (n.105T=) n.495T= c.1061T= (p.Val354=) c.138T= (n.138T=) c.1345T= (p.Ser449=) c.1444T= (p.Ser482=) c.1396T= (p.Ser466=) c.1390T= (p.Ser464=) c.1291T= (p.Ser431=) c.937T= (p.Ser313=)
1	g.154465270_154465271delinsTC	CA2480880307	IL6R	c.1297_1298delinsTC (p.Ser433=) c.105_106delinsTC (n.105_106delinsTC) n.495_496delinsTC c.1061_1062delinsTC (p.Val354=) c.138_139delinsTC (n.138_139delinsTC) c.1345_1346delinsTC (p.Ser449=) c.1444_1445delinsTC (p.Ser482=) c.1396_1397delinsTC (p.Ser466=) c.1390_1391delinsTC (p.Ser464=) c.1291_1292delinsTC (p.Ser431=) c.937_938delinsTC (p.Ser313=)
1	g.154465271C>A	CA342628598	IL6R	c.1298C>A (p.Ser433Tyr) c.106C>A (n.106C>A) n.496C>A c.1062C>A (p.Val354=) c.139C>A (n.139C>A) c.1346C>A (p.Ser449Tyr) c.1445C>A (p.Ser482Tyr) c.1397C>A (p.Ser466Tyr) c.1391C>A (p.Ser464Tyr) c.1292C>A (p.Ser431Tyr) c.938C>A (p.Ser313Tyr)	ClinVar dbSNP gnomAD v3 gnomAD v4
1	g.154465271C=	CA2480880309	IL6R	c.1298C= (p.Ser433=) c.106C= (n.106C=) n.496C= c.1062C= (p.Val354=) c.139C= (n.139C=) c.1346C= (p.Ser449=) c.1445C= (p.Ser482=) c.1397C= (p.Ser466=) c.1391C= (p.Ser464=) c.1292C= (p.Ser431=) c.938C= (p.Ser313=)
1	g.154465271C>G	CA342628599	IL6R	c.1298C>G (p.Ser433Cys) c.106C>G (n.106C>G) n.496C>G c.1062C>G (p.Val354=) c.139C>G (n.139C>G) c.1346C>G (p.Ser449Cys) c.1445C>G (p.Ser482Cys) c.1397C>G (p.Ser466Cys) c.1391C>G (p.Ser464Cys) c.1292C>G (p.Ser431Cys) c.938C>G (p.Ser313Cys)
1	g.154465271C>T	CA342628600	IL6R	c.1298C>T (p.Ser433Phe) c.106C>T (n.106C>T) n.496C>T c.1062C>T (p.Val354=) c.139C>T (n.139C>T) c.1346C>T (p.Ser449Phe) c.1445C>T (p.Ser482Phe) c.1397C>T (p.Ser466Phe) c.1391C>T (p.Ser464Phe) c.1292C>T (p.Ser431Phe) c.938C>T (p.Ser313Phe)	dbSNP gnomAD v4
1	g.154465275del	CA1129341	IL6R	c.1302del (p.Ser435AlafsTer?) c.110del (n.110del) n.500del c.1066del (p.Gln356SerfsTer?) c.143del (n.143del) c.1350del (p.Ser451AlafsTer?) c.1449del (p.Ser484AlafsTer?) c.1401del (p.Ser468AlafsTer?) c.1395del (p.Ser466AlafsTer?) c.1296del (p.Ser433AlafsTer?) c.942del (p.Ser315AlafsTer?)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465272C>A	CA420975987	IL6R	c.1299C>A (p.Ser433=) c.107C>A (n.107C>A) n.497C>A c.1063C>A (p.Pro355Thr) c.140C>A (n.140C>A) c.1347C>A (p.Ser449=) c.1446C>A (p.Ser482=) c.1398C>A (p.Ser466=) c.1392C>A (p.Ser464=) c.1293C>A (p.Ser431=) c.939C>A (p.Ser313=)
1	g.154465272C=	CA2480880310	IL6R	c.1299C= (p.Ser433=) c.107C= (n.107C=) n.497C= c.1063C= (p.Pro355=) c.140C= (n.140C=) c.1347C= (p.Ser449=) c.1446C= (p.Ser482=) c.1398C= (p.Ser466=) c.1392C= (p.Ser464=) c.1293C= (p.Ser431=) c.939C= (p.Ser313=)
1	g.154465272C>G	CA420975985	IL6R	c.1299C>G (p.Ser433=) c.107C>G (n.107C>G) n.497C>G c.1063C>G (p.Pro355Ala) c.140C>G (n.140C>G) c.1347C>G (p.Ser449=) c.1446C>G (p.Ser482=) c.1398C>G (p.Ser466=) c.1392C>G (p.Ser464=) c.1293C>G (p.Ser431=) c.939C>G (p.Ser313=)
1	g.154465272C>T	CA420975986	IL6R	c.1299C>T (p.Ser433=) c.107C>T (n.107C>T) n.497C>T c.1063C>T (p.Pro355Ser) c.140C>T (n.140C>T) c.1347C>T (p.Ser449=) c.1446C>T (p.Ser482=) c.1398C>T (p.Ser466=) c.1392C>T (p.Ser464=) c.1293C>T (p.Ser431=) c.939C>T (p.Ser313=)	ClinVar dbSNP gnomAD v4
1	g.154465273C>A	CA342628601	IL6R	c.1300C>A (p.Pro434Thr) c.108C>A (n.108C>A) n.498C>A c.1064C>A (p.Pro355His) c.141C>A (n.141C>A) c.1348C>A (p.Pro450Thr) c.1447C>A (p.Pro483Thr) c.1399C>A (p.Pro467Thr) c.1393C>A (p.Pro465Thr) c.1294C>A (p.Pro432Thr) c.940C>A (p.Pro314Thr)
1	g.154465273C=	CA1142341921	IL6R	c.1300C= (p.Pro434=) c.108C= (n.108C=) n.498C= c.1064C= (p.Pro355=) c.141C= (n.141C=) c.1348C= (p.Pro450=) c.1447C= (p.Pro483=) c.1399C= (p.Pro467=) c.1393C= (p.Pro465=) c.1294C= (p.Pro432=) c.940C= (p.Pro314=)
1	g.154465273C>G	CA342628602	IL6R	c.1300C>G (p.Pro434Ala) c.108C>G (n.108C>G) n.498C>G c.1064C>G (p.Pro355Arg) c.141C>G (n.141C>G) c.1348C>G (p.Pro450Ala) c.1447C>G (p.Pro483Ala) c.1399C>G (p.Pro467Ala) c.1393C>G (p.Pro465Ala) c.1294C>G (p.Pro432Ala) c.940C>G (p.Pro314Ala)
1	g.154465273C>T	CA1129342	IL6R	c.1300C>T (p.Pro434Ser) c.108C>T (n.108C>T) n.498C>T c.1064C>T (p.Pro355Leu) c.141C>T (n.141C>T) c.1348C>T (p.Pro450Ser) c.1447C>T (p.Pro483Ser) c.1399C>T (p.Pro467Ser) c.1393C>T (p.Pro465Ser) c.1294C>T (p.Pro432Ser) c.940C>T (p.Pro314Ser)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465274C>A	CA342628605	IL6R	c.1301C>A (p.Pro434His) c.109C>A (n.109C>A) n.499C>A c.1065C>A (p.Pro355=) c.142C>A (n.142C>A) c.1349C>A (p.Pro450His) c.1448C>A (p.Pro483His) c.1400C>A (p.Pro467His) c.1394C>A (p.Pro465His) c.1295C>A (p.Pro432His) c.941C>A (p.Pro314His)
1	g.154465274C>G	CA342628604	IL6R	c.1301C>G (p.Pro434Arg) c.109C>G (n.109C>G) n.499C>G c.1065C>G (p.Pro355=) c.142C>G (n.142C>G) c.1349C>G (p.Pro450Arg) c.1448C>G (p.Pro483Arg) c.1400C>G (p.Pro467Arg) c.1394C>G (p.Pro465Arg) c.1295C>G (p.Pro432Arg) c.941C>G (p.Pro314Arg)	gnomAD v4
1	g.154465274C>T	CA342628603	IL6R	c.1301C>T (p.Pro434Leu) c.109C>T (n.109C>T) n.499C>T c.1065C>T (p.Pro355=) c.142C>T (n.142C>T) c.1349C>T (p.Pro450Leu) c.1448C>T (p.Pro483Leu) c.1400C>T (p.Pro467Leu) c.1394C>T (p.Pro465Leu) c.1295C>T (p.Pro432Leu) c.941C>T (p.Pro314Leu)
1	g.154465275C>A	CA420975988	IL6R	c.1302C>A (p.Pro434=) c.110C>A (n.110C>A) n.500C>A c.1066C>A (p.Gln356Lys) c.143C>A (n.143C>A) c.1350C>A (p.Pro450=) c.1449C>A (p.Pro483=) c.1401C>A (p.Pro467=) c.1395C>A (p.Pro465=) c.1296C>A (p.Pro432=) c.942C>A (p.Pro314=)
1	g.154465275C>G	CA420975989	IL6R	c.1302C>G (p.Pro434=) c.110C>G (n.110C>G) n.500C>G c.1066C>G (p.Gln356Glu) c.143C>G (n.143C>G) c.1350C>G (p.Pro450=) c.1449C>G (p.Pro483=) c.1401C>G (p.Pro467=) c.1395C>G (p.Pro465=) c.1296C>G (p.Pro432=) c.942C>G (p.Pro314=)
1	g.154465275C>T	CA420975990	IL6R	c.1302C>T (p.Pro434=) c.110C>T (n.110C>T) n.500C>T c.1066C>T (p.Gln356Ter) c.143C>T (n.143C>T) c.1350C>T (p.Pro450=) c.1449C>T (p.Pro483=) c.1401C>T (p.Pro467=) c.1395C>T (p.Pro465=) c.1296C>T (p.Pro432=) c.942C>T (p.Pro314=)
1	g.154465276A=	CA2480880311	IL6R	c.1303A= (p.Ser435=) c.111A= (n.111A=) n.501A= c.1067A= (p.Gln356=) c.144A= (n.144A=) c.1351A= (p.Ser451=) c.1450A= (p.Ser484=) c.1402A= (p.Ser468=) c.1396A= (p.Ser466=) c.1297A= (p.Ser433=) c.943A= (p.Ser315=)
1	g.154465276A>C	CA342628606	IL6R	c.1303A>C (p.Ser435Arg) c.111A>C (n.111A>C) n.501A>C c.1067A>C (p.Gln356Pro) c.144A>C (n.144A>C) c.1351A>C (p.Ser451Arg) c.1450A>C (p.Ser484Arg) c.1402A>C (p.Ser468Arg) c.1396A>C (p.Ser466Arg) c.1297A>C (p.Ser433Arg) c.943A>C (p.Ser315Arg)
1	g.154465276A>G	CA1129343	IL6R	c.1303A>G (p.Ser435Gly) c.111A>G (n.111A>G) n.501A>G c.1067A>G (p.Gln356Arg) c.144A>G (n.144A>G) c.1351A>G (p.Ser451Gly) c.1450A>G (p.Ser484Gly) c.1402A>G (p.Ser468Gly) c.1396A>G (p.Ser466Gly) c.1297A>G (p.Ser433Gly) c.943A>G (p.Ser315Gly)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465276A>T	CA342628607	IL6R	c.1303A>T (p.Ser435Cys) c.111A>T (n.111A>T) n.501A>T c.1067A>T (p.Gln356Leu) c.144A>T (n.144A>T) c.1351A>T (p.Ser451Cys) c.1450A>T (p.Ser484Cys) c.1402A>T (p.Ser468Cys) c.1396A>T (p.Ser466Cys) c.1297A>T (p.Ser433Cys) c.943A>T (p.Ser315Cys)
1	g.154465276dup	CA2573909516	IL6R	c.1303dup (p.Ser435LysfsTer6) c.111dup (n.111dup) n.501dup c.1067dup (p.Gln357AlafsTer?) c.144dup (n.144dup) c.1351dup (p.Ser451LysfsTer6) c.1450dup (p.Ser484LysfsTer6) c.1402dup (p.Ser468LysfsTer6) c.1396dup (p.Ser466LysfsTer6) c.1297dup (p.Ser433LysfsTer6) c.943dup (p.Ser315LysfsTer6)
1	g.154465277G>A	CA342628608	IL6R	c.1304G>A (p.Ser435Asn) c.112G>A (n.112G>A) n.502G>A c.1068G>A (p.Gln356=) c.145G>A (n.145G>A) c.1352G>A (p.Ser451Asn) c.1451G>A (p.Ser484Asn) c.1403G>A (p.Ser468Asn) c.1397G>A (p.Ser466Asn) c.1298G>A (p.Ser433Asn) c.944G>A (p.Ser315Asn)
1	g.154465277G>C	CA342628609	IL6R	c.1304G>C (p.Ser435Thr) c.112G>C (n.112G>C) n.502G>C c.1068G>C (p.Gln356His) c.145G>C (n.145G>C) c.1352G>C (p.Ser451Thr) c.1451G>C (p.Ser484Thr) c.1403G>C (p.Ser468Thr) c.1397G>C (p.Ser466Thr) c.1298G>C (p.Ser433Thr) c.944G>C (p.Ser315Thr)
1	g.154465277G>T	CA342628610	IL6R	c.1304G>T (p.Ser435Ile) c.112G>T (n.112G>T) n.502G>T c.1068G>T (p.Gln356His) c.145G>T (n.145G>T) c.1352G>T (p.Ser451Ile) c.1451G>T (p.Ser484Ile) c.1403G>T (p.Ser468Ile) c.1397G>T (p.Ser466Ile) c.1298G>T (p.Ser433Ile) c.944G>T (p.Ser315Ile)
1	g.154465278C>A	CA342628611	IL6R	c.1305C>A (p.Ser435Arg) c.113C>A (n.113C>A) n.503C>A c.1069C>A (p.Gln357Lys) c.146C>A (n.146C>A) c.1353C>A (p.Ser451Arg) c.1452C>A (p.Ser484Arg) c.1404C>A (p.Ser468Arg) c.1398C>A (p.Ser466Arg) c.1299C>A (p.Ser433Arg) c.945C>A (p.Ser315Arg)
1	g.154465278C=	CA2480880312	IL6R	c.1305C= (p.Ser435=) c.113C= (n.113C=) n.503C= c.1069C= (p.Gln357=) c.146C= (n.146C=) c.1353C= (p.Ser451=) c.1452C= (p.Ser484=) c.1404C= (p.Ser468=) c.1398C= (p.Ser466=) c.1299C= (p.Ser433=) c.945C= (p.Ser315=)
1	g.154465278C>G	CA342628612	IL6R	c.1305C>G (p.Ser435Arg) c.113C>G (n.113C>G) n.503C>G c.1069C>G (p.Gln357Glu) c.146C>G (n.146C>G) c.1353C>G (p.Ser451Arg) c.1452C>G (p.Ser484Arg) c.1404C>G (p.Ser468Arg) c.1398C>G (p.Ser466Arg) c.1299C>G (p.Ser433Arg) c.945C>G (p.Ser315Arg)
1	g.154465278C>T	CA1129344	IL6R	c.1305C>T (p.Ser435=) c.113C>T (n.113C>T) n.503C>T c.1069C>T (p.Gln357Ter) c.146C>T (n.146C>T) c.1353C>T (p.Ser451=) c.1452C>T (p.Ser484=) c.1404C>T (p.Ser468=) c.1398C>T (p.Ser466=) c.1299C>T (p.Ser433=) c.945C>T (p.Ser315=)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465279A>C	CA342628613	IL6R	c.1306A>C (p.Ser436Arg) c.114A>C (n.114A>C) n.504A>C c.1070A>C (p.Gln357Pro) c.147A>C (n.147A>C) c.1354A>C (p.Ser452Arg) c.1453A>C (p.Ser485Arg) c.1405A>C (p.Ser469Arg) c.1399A>C (p.Ser467Arg) c.1300A>C (p.Ser434Arg) c.946A>C (p.Ser316Arg)
1	g.154465279A>G	CA342628614	IL6R	c.1306A>G (p.Ser436Gly) c.114A>G (n.114A>G) n.504A>G c.1070A>G (p.Gln357Arg) c.147A>G (n.147A>G) c.1354A>G (p.Ser452Gly) c.1453A>G (p.Ser485Gly) c.1405A>G (p.Ser469Gly) c.1399A>G (p.Ser467Gly) c.1300A>G (p.Ser434Gly) c.946A>G (p.Ser316Gly)
1	g.154465279A>T	CA342628615	IL6R	c.1306A>T (p.Ser436Cys) c.114A>T (n.114A>T) n.504A>T c.1070A>T (p.Gln357Leu) c.147A>T (n.147A>T) c.1354A>T (p.Ser452Cys) c.1453A>T (p.Ser485Cys) c.1405A>T (p.Ser469Cys) c.1399A>T (p.Ser467Cys) c.1300A>T (p.Ser434Cys) c.946A>T (p.Ser316Cys)
1	g.154465280G>A	CA342628617	IL6R	c.1307G>A (p.Ser436Asn) c.115G>A (n.115G>A) n.505G>A c.1071G>A (p.Gln357=) c.148G>A (n.148G>A) c.1355G>A (p.Ser452Asn) c.1454G>A (p.Ser485Asn) c.1406G>A (p.Ser469Asn) c.1400G>A (p.Ser467Asn) c.1301G>A (p.Ser434Asn) c.947G>A (p.Ser316Asn)
1	g.154465280G>C	CA342628618	IL6R	c.1307G>C (p.Ser436Thr) c.115G>C (n.115G>C) n.505G>C c.1071G>C (p.Gln357His) c.148G>C (n.148G>C) c.1355G>C (p.Ser452Thr) c.1454G>C (p.Ser485Thr) c.1406G>C (p.Ser469Thr) c.1400G>C (p.Ser467Thr) c.1301G>C (p.Ser434Thr) c.947G>C (p.Ser316Thr)	gnomAD v4
1	g.154465280G>T	CA342628616	IL6R	c.1307G>T (p.Ser436Ile) c.115G>T (n.115G>T) n.505G>T c.1071G>T (p.Gln357His) c.148G>T (n.148G>T) c.1355G>T (p.Ser452Ile) c.1454G>T (p.Ser485Ile) c.1406G>T (p.Ser469Ile) c.1400G>T (p.Ser467Ile) c.1301G>T (p.Ser434Ile) c.947G>T (p.Ser316Ile)
1	g.154465281C>A	CA342628619	IL6R	c.1308C>A (p.Ser436Arg) c.116C>A (n.116C>A) n.506C>A c.1072C>A (p.Pro358Thr) c.149C>A (n.149C>A) c.1356C>A (p.Ser452Arg) c.1455C>A (p.Ser485Arg) c.1407C>A (p.Ser469Arg) c.1401C>A (p.Ser467Arg) c.1302C>A (p.Ser434Arg) c.948C>A (p.Ser316Arg)
1	g.154465281C=	CA1147508469	IL6R	c.1308C= (p.Ser436=) c.116C= (n.116C=) n.506C= c.1072C= (p.Pro358=) c.149C= (n.149C=) c.1356C= (p.Ser452=) c.1455C= (p.Ser485=) c.1407C= (p.Ser469=) c.1401C= (p.Ser467=) c.1302C= (p.Ser434=) c.948C= (p.Ser316=)
1	g.154465281C>G	CA342628620	IL6R	c.1308C>G (p.Ser436Arg) c.116C>G (n.116C>G) n.506C>G c.1072C>G (p.Pro358Ala) c.149C>G (n.149C>G) c.1356C>G (p.Ser452Arg) c.1455C>G (p.Ser485Arg) c.1407C>G (p.Ser469Arg) c.1401C>G (p.Ser467Arg) c.1302C>G (p.Ser434Arg) c.948C>G (p.Ser316Arg)
1	g.154465281C>T	CA1129345	IL6R	c.1308C>T (p.Ser436=) c.116C>T (n.116C>T) n.506C>T c.1072C>T (p.Pro358Ser) c.149C>T (n.149C>T) c.1356C>T (p.Ser452=) c.1455C>T (p.Ser485=) c.1407C>T (p.Ser469=) c.1401C>T (p.Ser467=) c.1302C>T (p.Ser434=) c.948C>T (p.Ser316=)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465282C>A	CA342628621	IL6R	c.1309C>A (p.Leu437Met) c.117C>A (n.117C>A) n.507C>A c.1073C>A (p.Pro358His) c.150C>A (n.150C>A) c.1357C>A (p.Leu453Met) c.1456C>A (p.Leu486Met) c.1408C>A (p.Leu470Met) c.1402C>A (p.Leu468Met) c.1303C>A (p.Leu435Met) c.949C>A (p.Leu317Met)
1	g.154465282C>G	CA342628622	IL6R	c.1309C>G (p.Leu437Val) c.117C>G (n.117C>G) n.507C>G c.1073C>G (p.Pro358Arg) c.150C>G (n.150C>G) c.1357C>G (p.Leu453Val) c.1456C>G (p.Leu486Val) c.1408C>G (p.Leu470Val) c.1402C>G (p.Leu468Val) c.1303C>G (p.Leu435Val) c.949C>G (p.Leu317Val)
1	g.154465282C>T	CA420975991	IL6R	c.1309C>T (p.Leu437=) c.117C>T (n.117C>T) n.507C>T c.1073C>T (p.Pro358Leu) c.150C>T (n.150C>T) c.1357C>T (p.Leu453=) c.1456C>T (p.Leu486=) c.1408C>T (p.Leu470=) c.1402C>T (p.Leu468=) c.1303C>T (p.Leu435=) c.949C>T (p.Leu317=)	gnomAD v4
1	g.154465285_154465291del	CA2746186212	IL6R	c.1312_1318del (p.Gly438ThrfsTer?) c.120_126del (n.120_126del) n.510_516del c.1076_1082del (p.Gly359AspfsTer30) c.153_159del (n.153_159del) c.1360_1366del (p.Gly454ThrfsTer?) c.1459_1465del (p.Gly487ThrfsTer?) c.1411_1417del (p.Gly471ThrfsTer?) c.1405_1411del (p.Gly469ThrfsTer?) c.1306_1312del (p.Gly436ThrfsTer?) c.952_958del (p.Gly318ThrfsTer?)
1	g.154465283T>A	CA342628625	IL6R	c.1310T>A (p.Leu437Gln) c.118T>A (n.118T>A) n.508T>A c.1074T>A (p.Pro358=) c.151T>A (n.151T>A) c.1358T>A (p.Leu453Gln) c.1457T>A (p.Leu486Gln) c.1409T>A (p.Leu470Gln) c.1403T>A (p.Leu468Gln) c.1304T>A (p.Leu435Gln) c.950T>A (p.Leu317Gln)
1	g.154465283T>C	CA342628624	IL6R	c.1310T>C (p.Leu437Pro) c.118T>C (n.118T>C) n.508T>C c.1074T>C (p.Pro358=) c.151T>C (n.151T>C) c.1358T>C (p.Leu453Pro) c.1457T>C (p.Leu486Pro) c.1409T>C (p.Leu470Pro) c.1403T>C (p.Leu468Pro) c.1304T>C (p.Leu435Pro) c.950T>C (p.Leu317Pro)
1	g.154465283T>G	CA342628623	IL6R	c.1310T>G (p.Leu437Arg) c.118T>G (n.118T>G) n.508T>G c.1074T>G (p.Pro358=) c.151T>G (n.151T>G) c.1358T>G (p.Leu453Arg) c.1457T>G (p.Leu486Arg) c.1409T>G (p.Leu470Arg) c.1403T>G (p.Leu468Arg) c.1304T>G (p.Leu435Arg) c.950T>G (p.Leu317Arg)
1	g.154465284G>A	CA420975992	IL6R	c.1311G>A (p.Leu437=) c.119G>A (n.119G>A) n.509G>A c.1075G>A (p.Gly359Arg) c.152G>A (n.152G>A) c.1359G>A (p.Leu453=) c.1458G>A (p.Leu486=) c.1410G>A (p.Leu470=) c.1404G>A (p.Leu468=) c.1305G>A (p.Leu435=) c.951G>A (p.Leu317=)
1	g.154465284G>C	CA420975993	IL6R	c.1311G>C (p.Leu437=) c.119G>C (n.119G>C) n.509G>C c.1075G>C (p.Gly359Arg) c.152G>C (n.152G>C) c.1359G>C (p.Leu453=) c.1458G>C (p.Leu486=) c.1410G>C (p.Leu470=) c.1404G>C (p.Leu468=) c.1305G>C (p.Leu435=) c.951G>C (p.Leu317=)
1	g.154465284G>T	CA420975994	IL6R	c.1311G>T (p.Leu437=) c.119G>T (n.119G>T) n.509G>T c.1075G>T (p.Gly359Trp) c.152G>T (n.152G>T) c.1359G>T (p.Leu453=) c.1458G>T (p.Leu486=) c.1410G>T (p.Leu470=) c.1404G>T (p.Leu468=) c.1305G>T (p.Leu435=) c.951G>T (p.Leu317=)
1	g.154465285G>A	CA342628626	IL6R	c.1312G>A (p.Gly438Arg) c.120G>A (n.120G>A) n.510G>A c.1076G>A (p.Gly359Glu) c.153G>A (n.153G>A) c.1360G>A (p.Gly454Arg) c.1459G>A (p.Gly487Arg) c.1411G>A (p.Gly471Arg) c.1405G>A (p.Gly469Arg) c.1306G>A (p.Gly436Arg) c.952G>A (p.Gly318Arg)
1	g.154465285G>C	CA342628627	IL6R	c.1312G>C (p.Gly438Arg) c.120G>C (n.120G>C) n.510G>C c.1076G>C (p.Gly359Ala) c.153G>C (n.153G>C) c.1360G>C (p.Gly454Arg) c.1459G>C (p.Gly487Arg) c.1411G>C (p.Gly471Arg) c.1405G>C (p.Gly469Arg) c.1306G>C (p.Gly436Arg) c.952G>C (p.Gly318Arg)
1	g.154465285G=	CA2480880313	IL6R	c.1312G= (p.Gly438=) c.120G= (n.120G=) n.510G= c.1076G= (p.Gly359=) c.153G= (n.153G=) c.1360G= (p.Gly454=) c.1459G= (p.Gly487=) c.1411G= (p.Gly471=) c.1405G= (p.Gly469=) c.1306G= (p.Gly436=) c.952G= (p.Gly318=)
1	g.154465285G>T	CA342628628	IL6R	c.1312G>T (p.Gly438Trp) c.120G>T (n.120G>T) n.510G>T c.1076G>T (p.Gly359Val) c.153G>T (n.153G>T) c.1360G>T (p.Gly454Trp) c.1459G>T (p.Gly487Trp) c.1411G>T (p.Gly471Trp) c.1405G>T (p.Gly469Trp) c.1306G>T (p.Gly436Trp) c.952G>T (p.Gly318Trp)	dbSNP gnomAD v3 gnomAD v4
1	g.154465286G>A	CA30816533	IL6R	c.1313G>A (p.Gly438Glu) c.121G>A (n.121G>A) n.511G>A c.1077G>A (p.Gly359=) c.154G>A (n.154G>A) c.1361G>A (p.Gly454Glu) c.1460G>A (p.Gly487Glu) c.1412G>A (p.Gly471Glu) c.1406G>A (p.Gly469Glu) c.1307G>A (p.Gly436Glu) c.953G>A (p.Gly318Glu)	dbSNP gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465286G>C	CA342628629	IL6R	c.1313G>C (p.Gly438Ala) c.121G>C (n.121G>C) n.511G>C c.1077G>C (p.Gly359=) c.154G>C (n.154G>C) c.1361G>C (p.Gly454Ala) c.1460G>C (p.Gly487Ala) c.1412G>C (p.Gly471Ala) c.1406G>C (p.Gly469Ala) c.1307G>C (p.Gly436Ala) c.953G>C (p.Gly318Ala)	gnomAD v4
1	g.154465286G=	CA2480880314	IL6R	c.1313G= (p.Gly438=) c.121G= (n.121G=) n.511G= c.1077G= (p.Gly359=) c.154G= (n.154G=) c.1361G= (p.Gly454=) c.1460G= (p.Gly487=) c.1412G= (p.Gly471=) c.1406G= (p.Gly469=) c.1307G= (p.Gly436=) c.953G= (p.Gly318=)
1	g.154465286G>T	CA342628630	IL6R	c.1313G>T (p.Gly438Val) c.121G>T (n.121G>T) n.511G>T c.1077G>T (p.Gly359=) c.154G>T (n.154G>T) c.1361G>T (p.Gly454Val) c.1460G>T (p.Gly487Val) c.1412G>T (p.Gly471Val) c.1406G>T (p.Gly469Val) c.1307G>T (p.Gly436Val) c.953G>T (p.Gly318Val)
1	g.154465287G>A	CA420975997	IL6R	c.1314G>A (p.Gly438=) c.122G>A (n.122G>A) n.512G>A c.1078G>A (p.Val360Ile) c.155G>A (n.155G>A) c.1362G>A (p.Gly454=) c.1461G>A (p.Gly487=) c.1413G>A (p.Gly471=) c.1407G>A (p.Gly469=) c.1308G>A (p.Gly436=) c.954G>A (p.Gly318=)
1	g.154465287G>C	CA420975995	IL6R	c.1314G>C (p.Gly438=) c.122G>C (n.122G>C) n.512G>C c.1078G>C (p.Val360Leu) c.155G>C (n.155G>C) c.1362G>C (p.Gly454=) c.1461G>C (p.Gly487=) c.1413G>C (p.Gly471=) c.1407G>C (p.Gly469=) c.1308G>C (p.Gly436=) c.954G>C (p.Gly318=)
1	g.154465287G>T	CA420975996	IL6R	c.1314G>T (p.Gly438=) c.122G>T (n.122G>T) n.512G>T c.1078G>T (p.Val360Phe) c.155G>T (n.155G>T) c.1362G>T (p.Gly454=) c.1461G>T (p.Gly487=) c.1413G>T (p.Gly471=) c.1407G>T (p.Gly469=) c.1308G>T (p.Gly436=) c.954G>T (p.Gly318=)	gnomAD v4
1	g.154465288T>A	CA342628631	IL6R	c.1315T>A (p.Ser439Thr) c.123T>A (n.123T>A) n.513T>A c.1079T>A (p.Val360Asp) c.156T>A (n.156T>A) c.1363T>A (p.Ser455Thr) c.1462T>A (p.Ser488Thr) c.1414T>A (p.Ser472Thr) c.1408T>A (p.Ser470Thr) c.1309T>A (p.Ser437Thr) c.955T>A (p.Ser319Thr)
1	g.154465288T>C	CA342628633	IL6R	c.1315T>C (p.Ser439Pro) c.123T>C (n.123T>C) n.513T>C c.1079T>C (p.Val360Ala) c.156T>C (n.156T>C) c.1363T>C (p.Ser455Pro) c.1462T>C (p.Ser488Pro) c.1414T>C (p.Ser472Pro) c.1408T>C (p.Ser470Pro) c.1309T>C (p.Ser437Pro) c.955T>C (p.Ser319Pro)
1	g.154465288T>G	CA342628632	IL6R	c.1315T>G (p.Ser439Ala) c.123T>G (n.123T>G) n.513T>G c.1079T>G (p.Val360Gly) c.156T>G (n.156T>G) c.1363T>G (p.Ser455Ala) c.1462T>G (p.Ser488Ala) c.1414T>G (p.Ser472Ala) c.1408T>G (p.Ser470Ala) c.1309T>G (p.Ser437Ala) c.955T>G (p.Ser319Ala)
1	g.154465289C>A	CA342628634	IL6R	c.1316C>A (p.Ser439Tyr) c.124C>A (n.124C>A) n.514C>A c.1080C>A (p.Val360=) c.157C>A (n.157C>A) c.1364C>A (p.Ser455Tyr) c.1463C>A (p.Ser488Tyr) c.1415C>A (p.Ser472Tyr) c.1409C>A (p.Ser470Tyr) c.1310C>A (p.Ser437Tyr) c.956C>A (p.Ser319Tyr)
1	g.154465289C>G	CA342628635	IL6R	c.1316C>G (p.Ser439Cys) c.124C>G (n.124C>G) n.514C>G c.1080C>G (p.Val360=) c.157C>G (n.157C>G) c.1364C>G (p.Ser455Cys) c.1463C>G (p.Ser488Cys) c.1415C>G (p.Ser472Cys) c.1409C>G (p.Ser470Cys) c.1310C>G (p.Ser437Cys) c.956C>G (p.Ser319Cys)
1	g.154465289C>T	CA342628636	IL6R	c.1316C>T (p.Ser439Phe) c.124C>T (n.124C>T) n.514C>T c.1080C>T (p.Val360=) c.157C>T (n.157C>T) c.1364C>T (p.Ser455Phe) c.1463C>T (p.Ser488Phe) c.1415C>T (p.Ser472Phe) c.1409C>T (p.Ser470Phe) c.1310C>T (p.Ser437Phe) c.956C>T (p.Ser319Phe)
1	g.154465290T>A	CA420975998	IL6R	c.1317T>A (p.Ser439=) c.125T>A (n.125T>A) n.515T>A c.1081T>A (p.Ter361Arg) c.158T>A (n.158T>A) c.1365T>A (p.Ser455=) c.1464T>A (p.Ser488=) c.1416T>A (p.Ser472=) c.1410T>A (p.Ser470=) c.1311T>A (p.Ser437=) c.957T>A (p.Ser319=)
1	g.154465290T>C	CA420975999	IL6R	c.1317T>C (p.Ser439=) c.125T>C (n.125T>C) n.515T>C c.1081T>C (p.Ter361Arg) c.158T>C (n.158T>C) c.1365T>C (p.Ser455=) c.1464T>C (p.Ser488=) c.1416T>C (p.Ser472=) c.1410T>C (p.Ser470=) c.1311T>C (p.Ser437=) c.957T>C (p.Ser319=)	gnomAD v4
1	g.154465290T>G	CA420976000	IL6R	c.1317T>G (p.Ser439=) c.125T>G (n.125T>G) n.515T>G c.1081T>G (p.Ter361Gly) c.158T>G (n.158T>G) c.1365T>G (p.Ser455=) c.1464T>G (p.Ser488=) c.1416T>G (p.Ser472=) c.1410T>G (p.Ser470=) c.1311T>G (p.Ser437=) c.957T>G (p.Ser319=)
1	g.154465291G>A	CA342628637	IL6R	c.1318G>A (p.Asp440Asn) c.126G>A (n.126G>A) n.516G>A c.1082G>A (p.Ter361=) c.159G>A (n.159G>A) c.1366G>A (p.Asp456Asn) c.1465G>A (p.Asp489Asn) c.1417G>A (p.Asp473Asn) c.1411G>A (p.Asp471Asn) c.1312G>A (p.Asp438Asn) c.958G>A (p.Asp320Asn)
1	g.154465291G>C	CA342628638	IL6R	c.1318G>C (p.Asp440His) c.126G>C (n.126G>C) n.516G>C c.1082G>C (p.Ter361Ser) c.159G>C (n.159G>C) c.1366G>C (p.Asp456His) c.1465G>C (p.Asp489His) c.1417G>C (p.Asp473His) c.1411G>C (p.Asp471His) c.1312G>C (p.Asp438His) c.958G>C (p.Asp320His)
1	g.154465291G>T	CA342628639	IL6R	c.1318G>T (p.Asp440Tyr) c.126G>T (n.126G>T) n.516G>T c.1082G>T (p.Ter361Leu) c.159G>T (n.159G>T) c.1366G>T (p.Asp456Tyr) c.1465G>T (p.Asp489Tyr) c.1417G>T (p.Asp473Tyr) c.1411G>T (p.Asp471Tyr) c.1312G>T (p.Asp438Tyr) c.958G>T (p.Asp320Tyr)
1	g.154465292A>C	CA342628640	IL6R	c.1319A>C (p.Asp440Ala) c.127A>C (n.127A>C) n.517A>C c.1083A>C (p.Ter361Cys) c.160A>C (n.160A>C) c.1367A>C (p.Asp456Ala) c.1466A>C (p.Asp489Ala) c.1418A>C (p.Asp473Ala) c.1412A>C (p.Asp471Ala) c.1313A>C (p.Asp438Ala) c.959A>C (p.Asp320Ala)
1	g.154465292A>G	CA342628641	IL6R	c.1319A>G (p.Asp440Gly) c.127A>G (n.127A>G) n.517A>G c.1083A>G (p.Ter361Trp) c.160A>G (n.160A>G) c.1367A>G (p.Asp456Gly) c.1466A>G (p.Asp489Gly) c.1418A>G (p.Asp473Gly) c.1412A>G (p.Asp471Gly) c.1313A>G (p.Asp438Gly) c.959A>G (p.Asp320Gly)
1	g.154465292A>T	CA342628642	IL6R	c.1319A>T (p.Asp440Val) c.127A>T (n.127A>T) n.517A>T c.1083A>T (p.Ter361Cys) c.160A>T (n.160A>T) c.1367A>T (p.Asp456Val) c.1466A>T (p.Asp489Val) c.1418A>T (p.Asp473Val) c.1412A>T (p.Asp471Val) c.1313A>T (p.Asp438Val) c.959A>T (p.Asp320Val)
1	g.154465293C>A	CA342628643	IL6R	c.1320C>A (p.Asp440Glu) c.128C>A (n.128C>A) n.518C>A c.1C>A (n.1C>A) c.161C>A (n.161C>A) c.1368C>A (p.Asp456Glu) c.1467C>A (p.Asp489Glu) c.1419C>A (p.Asp473Glu) c.1413C>A (p.Asp471Glu) c.1314C>A (p.Asp438Glu) c.960C>A (p.Asp320Glu)
1	g.154465293C>G	CA342628644	IL6R	c.1320C>G (p.Asp440Glu) c.128C>G (n.128C>G) n.518C>G c.1C>G (n.1C>G) c.161C>G (n.161C>G) c.1368C>G (p.Asp456Glu) c.1467C>G (p.Asp489Glu) c.1419C>G (p.Asp473Glu) c.1413C>G (p.Asp471Glu) c.1314C>G (p.Asp438Glu) c.960C>G (p.Asp320Glu)
1	g.154465293C>T	CA420976001	IL6R	c.1320C>T (p.Asp440=) c.128C>T (n.128C>T) n.518C>T c.1C>T (n.1C>T) c.161C>T (n.161C>T) c.1368C>T (p.Asp456=) c.1467C>T (p.Asp489=) c.1419C>T (p.Asp473=) c.1413C>T (p.Asp471=) c.1314C>T (p.Asp438=) c.960C>T (p.Asp320=)
1	g.154465294A>C	CA342628647	IL6R	c.1321A>C (p.Asn441His) c.129A>C (n.129A>C) n.519A>C c.2A>C (n.2A>C) c.162A>C (n.162A>C) c.1369A>C (p.Asn457His) c.1468A>C (p.Asn490His) c.1420A>C (p.Asn474His) c.1414A>C (p.Asn472His) c.1315A>C (p.Asn439His) c.961A>C (p.Asn321His)
1	g.154465294A>G	CA342628646	IL6R	c.1321A>G (p.Asn441Asp) c.129A>G (n.129A>G) n.519A>G c.2A>G (n.2A>G) c.162A>G (n.162A>G) c.1369A>G (p.Asn457Asp) c.1468A>G (p.Asn490Asp) c.1420A>G (p.Asn474Asp) c.1414A>G (p.Asn472Asp) c.1315A>G (p.Asn439Asp) c.961A>G (p.Asn321Asp)
1	g.154465294A>T	CA342628645	IL6R	c.1321A>T (p.Asn441Tyr) c.129A>T (n.129A>T) n.519A>T c.2A>T (n.2A>T) c.162A>T (n.162A>T) c.1369A>T (p.Asn457Tyr) c.1468A>T (p.Asn490Tyr) c.1420A>T (p.Asn474Tyr) c.1414A>T (p.Asn472Tyr) c.1315A>T (p.Asn439Tyr) c.961A>T (p.Asn321Tyr)
1	g.154465295A>C	CA342628648	IL6R	c.1322A>C (p.Asn441Thr) c.130A>C (n.130A>C) n.520A>C c.3A>C (n.3A>C) c.163A>C (n.163A>C) c.1370A>C (p.Asn457Thr) c.1469A>C (p.Asn490Thr) c.1421A>C (p.Asn474Thr) c.1415A>C (p.Asn472Thr) c.1316A>C (p.Asn439Thr) c.962A>C (p.Asn321Thr)
1	g.154465295A>G	CA342628650	IL6R	c.1322A>G (p.Asn441Ser) c.130A>G (n.130A>G) n.520A>G c.3A>G (n.3A>G) c.163A>G (n.163A>G) c.1370A>G (p.Asn457Ser) c.1469A>G (p.Asn490Ser) c.1421A>G (p.Asn474Ser) c.1415A>G (p.Asn472Ser) c.1316A>G (p.Asn439Ser) c.962A>G (p.Asn321Ser)	gnomAD v4
1	g.154465295A>T	CA342628649	IL6R	c.1322A>T (p.Asn441Ile) c.130A>T (n.130A>T) n.520A>T c.3A>T (n.3A>T) c.163A>T (n.163A>T) c.1370A>T (p.Asn457Ile) c.1469A>T (p.Asn490Ile) c.1421A>T (p.Asn474Ile) c.1415A>T (p.Asn472Ile) c.1316A>T (p.Asn439Ile) c.962A>T (p.Asn321Ile)
1	g.154465296T>A	CA342628651	IL6R	c.1323T>A (p.Asn441Lys) c.131T>A (n.131T>A) n.521T>A c.4T>A (n.4T>A) c.164T>A (n.164T>A) c.1371T>A (p.Asn457Lys) c.1470T>A (p.Asn490Lys) c.1422T>A (p.Asn474Lys) c.1416T>A (p.Asn472Lys) c.1317T>A (p.Asn439Lys) c.963T>A (p.Asn321Lys)
1	g.154465296T>C	CA420976002	IL6R	c.1323T>C (p.Asn441=) c.131T>C (n.131T>C) n.521T>C c.4T>C (n.4T>C) c.164T>C (n.164T>C) c.1371T>C (p.Asn457=) c.1470T>C (p.Asn490=) c.1422T>C (p.Asn474=) c.1416T>C (p.Asn472=) c.1317T>C (p.Asn439=) c.963T>C (p.Asn321=)
1	g.154465296T>G	CA342628652	IL6R	c.1323T>G (p.Asn441Lys) c.131T>G (n.131T>G) n.521T>G c.4T>G (n.4T>G) c.164T>G (n.164T>G) c.1371T>G (p.Asn457Lys) c.1470T>G (p.Asn490Lys) c.1422T>G (p.Asn474Lys) c.1416T>G (p.Asn472Lys) c.1317T>G (p.Asn439Lys) c.963T>G (p.Asn321Lys)
1	g.154465297A=	CA2480880315	IL6R	c.1324A= (p.Thr442=) c.132A= (n.132A=) n.522A= c.5A= (n.5A=) c.165A= (n.165A=) c.1372A= (p.Thr458=) c.1471A= (p.Thr491=) c.1423A= (p.Thr475=) c.1417A= (p.Thr473=) c.1318A= (p.Thr440=) c.964A= (p.Thr322=)
1	g.154465297A>C	CA1129346	IL6R	c.1324A>C (p.Thr442Pro) c.132A>C (n.132A>C) n.522A>C c.5A>C (n.5A>C) c.165A>C (n.165A>C) c.1372A>C (p.Thr458Pro) c.1471A>C (p.Thr491Pro) c.1423A>C (p.Thr475Pro) c.1417A>C (p.Thr473Pro) c.1318A>C (p.Thr440Pro) c.964A>C (p.Thr322Pro)	dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465297A>G	CA342628653	IL6R	c.1324A>G (p.Thr442Ala) c.132A>G (n.132A>G) n.522A>G c.5A>G (n.5A>G) c.165A>G (n.165A>G) c.1372A>G (p.Thr458Ala) c.1471A>G (p.Thr491Ala) c.1423A>G (p.Thr475Ala) c.1417A>G (p.Thr473Ala) c.1318A>G (p.Thr440Ala) c.964A>G (p.Thr322Ala)
1	g.154465297A>T	CA342628654	IL6R	c.1324A>T (p.Thr442Ser) c.132A>T (n.132A>T) n.522A>T c.5A>T (n.5A>T) c.165A>T (n.165A>T) c.1372A>T (p.Thr458Ser) c.1471A>T (p.Thr491Ser) c.1423A>T (p.Thr475Ser) c.1417A>T (p.Thr473Ser) c.1318A>T (p.Thr440Ser) c.964A>T (p.Thr322Ser)
1	g.154465298C>A	CA342628655	IL6R	c.1325C>A (p.Thr442Asn) c.133C>A (n.133C>A) n.523C>A c.6C>A (n.6C>A) c.166C>A (n.166C>A) c.1373C>A (p.Thr458Asn) c.1472C>A (p.Thr491Asn) c.1424C>A (p.Thr475Asn) c.1418C>A (p.Thr473Asn) c.1319C>A (p.Thr440Asn) c.965C>A (p.Thr322Asn)
1	g.154465298C>G	CA342628656	IL6R	c.1325C>G (p.Thr442Ser) c.133C>G (n.133C>G) n.523C>G c.6C>G (n.6C>G) c.166C>G (n.166C>G) c.1373C>G (p.Thr458Ser) c.1472C>G (p.Thr491Ser) c.1424C>G (p.Thr475Ser) c.1418C>G (p.Thr473Ser) c.1319C>G (p.Thr440Ser) c.965C>G (p.Thr322Ser)	gnomAD v4
1	g.154465298C>T	CA342628657	IL6R	c.1325C>T (p.Thr442Ile) c.133C>T (n.133C>T) n.523C>T c.6C>T (n.6C>T) c.166C>T (n.166C>T) c.1373C>T (p.Thr458Ile) c.1472C>T (p.Thr491Ile) c.1424C>T (p.Thr475Ile) c.1418C>T (p.Thr473Ile) c.1319C>T (p.Thr440Ile) c.965C>T (p.Thr322Ile)	gnomAD v4
1	g.154465299del	CA2573909562	IL6R	c.1326del (p.Ser443ArgfsTer?) c.134del (n.134del) n.524del c.7del (n.7del) c.167del (n.167del) c.1374del (p.Ser459ArgfsTer?) c.1473del (p.Ser492ArgfsTer?) c.1425del (p.Ser476ArgfsTer?) c.1419del (p.Ser474ArgfsTer?) c.1320del (p.Ser441ArgfsTer?) c.966del (p.Ser323ArgfsTer?)
1	g.154465299C>A	CA420976004	IL6R	c.1326C>A (p.Thr442=) c.134C>A (n.134C>A) n.524C>A c.7C>A (n.7C>A) c.167C>A (n.167C>A) c.1374C>A (p.Thr458=) c.1473C>A (p.Thr491=) c.1425C>A (p.Thr475=) c.1419C>A (p.Thr473=) c.1320C>A (p.Thr440=) c.966C>A (p.Thr322=)
1	g.154465299C=	CA2480880316	IL6R	c.1326C= (p.Thr442=) c.134C= (n.134C=) n.524C= c.7C= (n.7C=) c.167C= (n.167C=) c.1374C= (p.Thr458=) c.1473C= (p.Thr491=) c.1425C= (p.Thr475=) c.1419C= (p.Thr473=) c.1320C= (p.Thr440=) c.966C= (p.Thr322=)
1	g.154465299C>G	CA420976005	IL6R	c.1326C>G (p.Thr442=) c.134C>G (n.134C>G) n.524C>G c.7C>G (n.7C>G) c.167C>G (n.167C>G) c.1374C>G (p.Thr458=) c.1473C>G (p.Thr491=) c.1425C>G (p.Thr475=) c.1419C>G (p.Thr473=) c.1320C>G (p.Thr440=) c.966C>G (p.Thr322=)
1	g.154465299C>T	CA1129347	IL6R	c.1326C>T (p.Thr442=) c.134C>T (n.134C>T) n.524C>T c.7C>T (n.7C>T) c.167C>T (n.167C>T) c.1374C>T (p.Thr458=) c.1473C>T (p.Thr491=) c.1425C>T (p.Thr475=) c.1419C>T (p.Thr473=) c.1320C>T (p.Thr440=) c.966C>T (p.Thr322=)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465300T>A	CA342628658	IL6R	c.1327T>A (p.Ser443Thr) c.135T>A (n.135T>A) n.525T>A c.8T>A (n.8T>A) c.168T>A (n.168T>A) c.1375T>A (p.Ser459Thr) c.1474T>A (p.Ser492Thr) c.1426T>A (p.Ser476Thr) c.1420T>A (p.Ser474Thr) c.1321T>A (p.Ser441Thr) c.967T>A (p.Ser323Thr)	dbSNP gnomAD v2 gnomAD v4
1	g.154465300T>C	CA342628659	IL6R	c.1327T>C (p.Ser443Pro) c.135T>C (n.135T>C) n.525T>C c.8T>C (n.8T>C) c.168T>C (n.168T>C) c.1375T>C (p.Ser459Pro) c.1474T>C (p.Ser492Pro) c.1426T>C (p.Ser476Pro) c.1420T>C (p.Ser474Pro) c.1321T>C (p.Ser441Pro) c.967T>C (p.Ser323Pro)
1	g.154465300T>G	CA1129348	IL6R	c.1327T>G (p.Ser443Ala) c.135T>G (n.135T>G) n.525T>G c.8T>G (n.8T>G) c.168T>G (n.168T>G) c.1375T>G (p.Ser459Ala) c.1474T>G (p.Ser492Ala) c.1426T>G (p.Ser476Ala) c.1420T>G (p.Ser474Ala) c.1321T>G (p.Ser441Ala) c.967T>G (p.Ser323Ala)	dbSNP ExAC gnomAD v4
1	g.154465300T=	CA2480880318	IL6R	c.1327T= (p.Ser443=) c.135T= (n.135T=) n.525T= c.8T= (n.8T=) c.168T= (n.168T=) c.1375T= (p.Ser459=) c.1474T= (p.Ser492=) c.1426T= (p.Ser476=) c.1420T= (p.Ser474=) c.1321T= (p.Ser441=) c.967T= (p.Ser323=)
1	g.154465300_154465301delinsTC	CA2480880317	IL6R	c.1327_1328delinsTC (p.Ser443=) c.135_136delinsTC (n.135_136delinsTC) n.525_526delinsTC c.8_9delinsTC (n.8_9delinsTC) c.168_169delinsTC (n.168_169delinsTC) c.1375_1376delinsTC (p.Ser459=) c.1474_1475delinsTC (p.Ser492=) c.1426_1427delinsTC (p.Ser476=) c.1420_1421delinsTC (p.Ser474=) c.1321_1322delinsTC (p.Ser441=) c.967_968delinsTC (p.Ser323=)
1	g.154465301del	CA1129349	IL6R	c.1328del (p.Ser443Ter) c.136del (n.136del) n.526del c.9del (n.9del) c.169del (n.169del) c.1376del (p.Ser459Ter) c.1475del (p.Ser492Ter) c.1427del (p.Ser476Ter) c.1421del (p.Ser474Ter) c.1322del (p.Ser441Ter) c.968del (p.Ser323Ter)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465301C>A	CA30816557	IL6R	c.1328C>A (p.Ser443Ter) c.136C>A (n.136C>A) n.526C>A c.9C>A (n.9C>A) c.169C>A (n.169C>A) c.1376C>A (p.Ser459Ter) c.1475C>A (p.Ser492Ter) c.1427C>A (p.Ser476Ter) c.1421C>A (p.Ser474Ter) c.1322C>A (p.Ser441Ter) c.968C>A (p.Ser323Ter)	dbSNP
1	g.154465301C=	CA2480880319	IL6R	c.1328C= (p.Ser443=) c.136C= (n.136C=) n.526C= c.9C= (n.9C=) c.169C= (n.169C=) c.1376C= (p.Ser459=) c.1475C= (p.Ser492=) c.1427C= (p.Ser476=) c.1421C= (p.Ser474=) c.1322C= (p.Ser441=) c.968C= (p.Ser323=)
1	g.154465301C>G	CA1129350	IL6R	c.1328C>G (p.Ser443Trp) c.136C>G (n.136C>G) n.526C>G c.9C>G (n.9C>G) c.169C>G (n.169C>G) c.1376C>G (p.Ser459Trp) c.1475C>G (p.Ser492Trp) c.1427C>G (p.Ser476Trp) c.1421C>G (p.Ser474Trp) c.1322C>G (p.Ser441Trp) c.968C>G (p.Ser323Trp)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465301C>T	CA30816562	IL6R	c.1328C>T (p.Ser443Leu) c.136C>T (n.136C>T) n.526C>T c.9C>T (n.9C>T) c.169C>T (n.169C>T) c.1376C>T (p.Ser459Leu) c.1475C>T (p.Ser492Leu) c.1427C>T (p.Ser476Leu) c.1421C>T (p.Ser474Leu) c.1322C>T (p.Ser441Leu) c.968C>T (p.Ser323Leu)	dbSNP gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465302G>A	CA1129351	IL6R	c.1329G>A (p.Ser443=) c.137G>A (n.137G>A) n.527G>A c.10G>A (n.10G>A) c.170G>A (n.170G>A) c.1377G>A (p.Ser459=) c.1476G>A (p.Ser492=) c.1428G>A (p.Ser476=) c.1422G>A (p.Ser474=) c.1323G>A (p.Ser441=) c.969G>A (p.Ser323=)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4 COSMIC
1	g.154465302G>C	CA420976007	IL6R	c.1329G>C (p.Ser443=) c.137G>C (n.137G>C) n.527G>C c.10G>C (n.10G>C) c.170G>C (n.170G>C) c.1377G>C (p.Ser459=) c.1476G>C (p.Ser492=) c.1428G>C (p.Ser476=) c.1422G>C (p.Ser474=) c.1323G>C (p.Ser441=) c.969G>C (p.Ser323=)	gnomAD v4
1	g.154465302G=	CA2480880321	IL6R	c.1329G= (p.Ser443=) c.137G= (n.137G=) n.527G= c.10G= (n.10G=) c.170G= (n.170G=) c.1377G= (p.Ser459=) c.1476G= (p.Ser492=) c.1428G= (p.Ser476=) c.1422G= (p.Ser474=) c.1323G= (p.Ser441=) c.969G= (p.Ser323=)
1	g.154465302G>T	CA420976008	IL6R	c.1329G>T (p.Ser443=) c.137G>T (n.137G>T) n.527G>T c.10G>T (n.10G>T) c.170G>T (n.170G>T) c.1377G>T (p.Ser459=) c.1476G>T (p.Ser492=) c.1428G>T (p.Ser476=) c.1422G>T (p.Ser474=) c.1323G>T (p.Ser441=) c.969G>T (p.Ser323=)	COSMIC
1	g.154465302_154465303insGG	CA2480880320	IL6R	c.1329_1330insGG (p.Ser444GlyfsTer?) c.137_138insGG (n.137_138insGG) n.527_528insGG c.10_11insGG (n.10_11insGG) c.170_171insGG (n.170_171insGG) c.1377_1378insGG (p.Ser460GlyfsTer?) c.1476_1477insGG (p.Ser493GlyfsTer?) c.1428_1429insGG (p.Ser477GlyfsTer?) c.1422_1423insGG (p.Ser475GlyfsTer?) c.1323_1324insGG (p.Ser442GlyfsTer?) c.969_970insGG (p.Ser324GlyfsTer?)	dbSNP
1	g.154465303A>C	CA342628660	IL6R	c.1330A>C (p.Ser444Arg) c.138A>C (n.138A>C) n.528A>C c.11A>C (n.11A>C) c.171A>C (n.171A>C) c.1378A>C (p.Ser460Arg) c.1477A>C (p.Ser493Arg) c.1429A>C (p.Ser477Arg) c.1423A>C (p.Ser475Arg) c.1324A>C (p.Ser442Arg) c.970A>C (p.Ser324Arg)
1	g.154465303A>G	CA342628661	IL6R	c.1330A>G (p.Ser444Gly) c.138A>G (n.138A>G) n.528A>G c.11A>G (n.11A>G) c.171A>G (n.171A>G) c.1378A>G (p.Ser460Gly) c.1477A>G (p.Ser493Gly) c.1429A>G (p.Ser477Gly) c.1423A>G (p.Ser475Gly) c.1324A>G (p.Ser442Gly) c.970A>G (p.Ser324Gly)
1	g.154465303A>T	CA342628662	IL6R	c.1330A>T (p.Ser444Cys) c.138A>T (n.138A>T) n.528A>T c.11A>T (n.11A>T) c.171A>T (n.171A>T) c.1378A>T (p.Ser460Cys) c.1477A>T (p.Ser493Cys) c.1429A>T (p.Ser477Cys) c.1423A>T (p.Ser475Cys) c.1324A>T (p.Ser442Cys) c.970A>T (p.Ser324Cys)
1	g.154465304G>A	CA342628663	IL6R	c.1331G>A (p.Ser444Asn) c.139G>A (n.139G>A) n.529G>A c.12G>A (n.12G>A) c.172G>A (n.172G>A) c.1379G>A (p.Ser460Asn) c.1478G>A (p.Ser493Asn) c.1430G>A (p.Ser477Asn) c.1424G>A (p.Ser475Asn) c.1325G>A (p.Ser442Asn) c.971G>A (p.Ser324Asn)	ClinVar dbSNP gnomAD v2 gnomAD v4
1	g.154465304G>C	CA342628664	IL6R	c.1331G>C (p.Ser444Thr) c.139G>C (n.139G>C) n.529G>C c.12G>C (n.12G>C) c.172G>C (n.172G>C) c.1379G>C (p.Ser460Thr) c.1478G>C (p.Ser493Thr) c.1430G>C (p.Ser477Thr) c.1424G>C (p.Ser475Thr) c.1325G>C (p.Ser442Thr) c.971G>C (p.Ser324Thr)
1	g.154465304G=	CA2480880322	IL6R	c.1331G= (p.Ser444=) c.139G= (n.139G=) n.529G= c.12G= (n.12G=) c.172G= (n.172G=) c.1379G= (p.Ser460=) c.1478G= (p.Ser493=) c.1430G= (p.Ser477=) c.1424G= (p.Ser475=) c.1325G= (p.Ser442=) c.971G= (p.Ser324=)
1	g.154465304G>T	CA342628665	IL6R	c.1331G>T (p.Ser444Ile) c.139G>T (n.139G>T) n.529G>T c.12G>T (n.12G>T) c.172G>T (n.172G>T) c.1379G>T (p.Ser460Ile) c.1478G>T (p.Ser493Ile) c.1430G>T (p.Ser477Ile) c.1424G>T (p.Ser475Ile) c.1325G>T (p.Ser442Ile) c.971G>T (p.Ser324Ile)
1	g.154465305C>A	CA342628666	IL6R	c.1332C>A (p.Ser444Arg) c.140C>A (n.140C>A) n.530C>A c.13C>A (n.13C>A) c.173C>A (n.173C>A) c.1380C>A (p.Ser460Arg) c.1479C>A (p.Ser493Arg) c.1431C>A (p.Ser477Arg) c.1425C>A (p.Ser475Arg) c.1326C>A (p.Ser442Arg) c.972C>A (p.Ser324Arg)	dbSNP gnomAD v2 gnomAD v4
1	g.154465305C=	CA2480880323	IL6R	c.1332C= (p.Ser444=) c.140C= (n.140C=) n.530C= c.13C= (n.13C=) c.173C= (n.173C=) c.1380C= (p.Ser460=) c.1479C= (p.Ser493=) c.1431C= (p.Ser477=) c.1425C= (p.Ser475=) c.1326C= (p.Ser442=) c.972C= (p.Ser324=)
1	g.154465305C>G	CA342628667	IL6R	c.1332C>G (p.Ser444Arg) c.140C>G (n.140C>G) n.530C>G c.13C>G (n.13C>G) c.173C>G (n.173C>G) c.1380C>G (p.Ser460Arg) c.1479C>G (p.Ser493Arg) c.1431C>G (p.Ser477Arg) c.1425C>G (p.Ser475Arg) c.1326C>G (p.Ser442Arg) c.972C>G (p.Ser324Arg)
1	g.154465305C>T	CA420976009	IL6R	c.1332C>T (p.Ser444=) c.140C>T (n.140C>T) n.530C>T c.13C>T (n.13C>T) c.173C>T (n.173C>T) c.1380C>T (p.Ser460=) c.1479C>T (p.Ser493=) c.1431C>T (p.Ser477=) c.1425C>T (p.Ser475=) c.1326C>T (p.Ser442=) c.972C>T (p.Ser324=)
1	g.154465306C>A	CA342628668	IL6R	c.1333C>A (p.His445Asn) c.141C>A (n.141C>A) n.531C>A c.14C>A (n.14C>A) c.174C>A (n.174C>A) c.1381C>A (p.His461Asn) c.1480C>A (p.His494Asn) c.1432C>A (p.His478Asn) c.1426C>A (p.His476Asn) c.1327C>A (p.His443Asn) c.973C>A (p.His325Asn)
1	g.154465306C=	CA2480880324	IL6R	c.1333C= (p.His445=) c.141C= (n.141C=) n.531C= c.14C= (n.14C=) c.174C= (n.174C=) c.1381C= (p.His461=) c.1480C= (p.His494=) c.1432C= (p.His478=) c.1426C= (p.His476=) c.1327C= (p.His443=) c.973C= (p.His325=)
1	g.154465306C>G	CA342628669	IL6R	c.1333C>G (p.His445Asp) c.141C>G (n.141C>G) n.531C>G c.14C>G (n.14C>G) c.174C>G (n.174C>G) c.1381C>G (p.His461Asp) c.1480C>G (p.His494Asp) c.1432C>G (p.His478Asp) c.1426C>G (p.His476Asp) c.1327C>G (p.His443Asp) c.973C>G (p.His325Asp)
1	g.154465306C>T	CA1129352	IL6R	c.1333C>T (p.His445Tyr) c.141C>T (n.141C>T) n.531C>T c.14C>T (n.14C>T) c.174C>T (n.174C>T) c.1381C>T (p.His461Tyr) c.1480C>T (p.His494Tyr) c.1432C>T (p.His478Tyr) c.1426C>T (p.His476Tyr) c.1327C>T (p.His443Tyr) c.973C>T (p.His325Tyr)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465307A>C	CA342628670	IL6R	c.1334A>C (p.His445Pro) c.142A>C (n.142A>C) n.532A>C c.15A>C (n.15A>C) c.175A>C (n.175A>C) c.1382A>C (p.His461Pro) c.1481A>C (p.His494Pro) c.1433A>C (p.His478Pro) c.1427A>C (p.His476Pro) c.1328A>C (p.His443Pro) c.974A>C (p.His325Pro)
1	g.154465307A>G	CA342628671	IL6R	c.1334A>G (p.His445Arg) c.142A>G (n.142A>G) n.532A>G c.15A>G (n.15A>G) c.175A>G (n.175A>G) c.1382A>G (p.His461Arg) c.1481A>G (p.His494Arg) c.1433A>G (p.His478Arg) c.1427A>G (p.His476Arg) c.1328A>G (p.His443Arg) c.974A>G (p.His325Arg)	gnomAD v4
1	g.154465307A>T	CA342628672	IL6R	c.1334A>T (p.His445Leu) c.142A>T (n.142A>T) n.532A>T c.15A>T (n.15A>T) c.175A>T (n.175A>T) c.1382A>T (p.His461Leu) c.1481A>T (p.His494Leu) c.1433A>T (p.His478Leu) c.1427A>T (p.His476Leu) c.1328A>T (p.His443Leu) c.974A>T (p.His325Leu)
1	g.154465308C>A	CA342628673	IL6R	c.1335C>A (p.His445Gln) c.143C>A (n.143C>A) n.533C>A c.16C>A (n.16C>A) c.176C>A (n.176C>A) c.1383C>A (p.His461Gln) c.1482C>A (p.His494Gln) c.1434C>A (p.His478Gln) c.1428C>A (p.His476Gln) c.1329C>A (p.His443Gln) c.975C>A (p.His325Gln)
1	g.154465308C>G	CA342628674	IL6R	c.1335C>G (p.His445Gln) c.143C>G (n.143C>G) n.533C>G c.16C>G (n.16C>G) c.176C>G (n.176C>G) c.1383C>G (p.His461Gln) c.1482C>G (p.His494Gln) c.1434C>G (p.His478Gln) c.1428C>G (p.His476Gln) c.1329C>G (p.His443Gln) c.975C>G (p.His325Gln)
1	g.154465308C>T	CA420976010	IL6R	c.1335C>T (p.His445=) c.143C>T (n.143C>T) n.533C>T c.16C>T (n.16C>T) c.176C>T (n.176C>T) c.1383C>T (p.His461=) c.1482C>T (p.His494=) c.1434C>T (p.His478=) c.1428C>T (p.His476=) c.1329C>T (p.His443=) c.975C>T (p.His325=)
1	g.154465309A=	CA2480880325	IL6R	c.1336A= (p.Asn446=) c.144A= (n.144A=) n.534A= c.17A= (n.17A=) c.177A= (n.177A=) c.1384A= (p.Asn462=) c.1483A= (p.Asn495=) c.1435A= (p.Asn479=) c.1429A= (p.Asn477=) c.1330A= (p.Asn444=) c.976A= (p.Asn326=)
1	g.154465309A>C	CA342628675	IL6R	c.1336A>C (p.Asn446His) c.144A>C (n.144A>C) n.534A>C c.17A>C (n.17A>C) c.177A>C (n.177A>C) c.1384A>C (p.Asn462His) c.1483A>C (p.Asn495His) c.1435A>C (p.Asn479His) c.1429A>C (p.Asn477His) c.1330A>C (p.Asn444His) c.976A>C (p.Asn326His)	COSMIC
1	g.154465309A>G	CA342628676	IL6R	c.1336A>G (p.Asn446Asp) c.144A>G (n.144A>G) n.534A>G c.17A>G (n.17A>G) c.177A>G (n.177A>G) c.1384A>G (p.Asn462Asp) c.1483A>G (p.Asn495Asp) c.1435A>G (p.Asn479Asp) c.1429A>G (p.Asn477Asp) c.1330A>G (p.Asn444Asp) c.976A>G (p.Asn326Asp)
1	g.154465309A>T	CA342628677	IL6R	c.1336A>T (p.Asn446Tyr) c.144A>T (n.144A>T) n.534A>T c.17A>T (n.17A>T) c.177A>T (n.177A>T) c.1384A>T (p.Asn462Tyr) c.1483A>T (p.Asn495Tyr) c.1435A>T (p.Asn479Tyr) c.1429A>T (p.Asn477Tyr) c.1330A>T (p.Asn444Tyr) c.976A>T (p.Asn326Tyr)	dbSNP gnomAD v3 gnomAD v4
1	g.154465310del	CA2648156787	IL6R	c.1337del (p.Asn446ThrfsTer?) c.145del (n.145del) n.535del c.18del (n.18del) c.178del (n.178del) c.1385del (p.Asn462ThrfsTer?) c.1484del (p.Asn495ThrfsTer?) c.1436del (p.Asn479ThrfsTer?) c.1430del (p.Asn477ThrfsTer?) c.1331del (p.Asn444ThrfsTer?) c.977del (p.Asn326ThrfsTer?)	gnomAD v4
1	g.154465310A>C	CA342628678	IL6R	c.1337A>C (p.Asn446Thr) c.145A>C (n.145A>C) n.535A>C c.18A>C (n.18A>C) c.178A>C (n.178A>C) c.1385A>C (p.Asn462Thr) c.1484A>C (p.Asn495Thr) c.1436A>C (p.Asn479Thr) c.1430A>C (p.Asn477Thr) c.1331A>C (p.Asn444Thr) c.977A>C (p.Asn326Thr)
1	g.154465310A>G	CA342628679	IL6R	c.1337A>G (p.Asn446Ser) c.145A>G (n.145A>G) n.535A>G c.18A>G (n.18A>G) c.178A>G (n.178A>G) c.1385A>G (p.Asn462Ser) c.1484A>G (p.Asn495Ser) c.1436A>G (p.Asn479Ser) c.1430A>G (p.Asn477Ser) c.1331A>G (p.Asn444Ser) c.977A>G (p.Asn326Ser)	COSMIC
1	g.154465310A>T	CA342628680	IL6R	c.1337A>T (p.Asn446Ile) c.145A>T (n.145A>T) n.535A>T c.18A>T (n.18A>T) c.178A>T (n.178A>T) c.1385A>T (p.Asn462Ile) c.1484A>T (p.Asn495Ile) c.1436A>T (p.Asn479Ile) c.1430A>T (p.Asn477Ile) c.1331A>T (p.Asn444Ile) c.977A>T (p.Asn326Ile)
1	g.154465311C>A	CA342628681	IL6R	c.1338C>A (p.Asn446Lys) c.146C>A (n.146C>A) n.536C>A c.19C>A (n.19C>A) c.179C>A (n.179C>A) c.1386C>A (p.Asn462Lys) c.1485C>A (p.Asn495Lys) c.1437C>A (p.Asn479Lys) c.1431C>A (p.Asn477Lys) c.1332C>A (p.Asn444Lys) c.978C>A (p.Asn326Lys)
1	g.154465311C>G	CA342628682	IL6R	c.1338C>G (p.Asn446Lys) c.146C>G (n.146C>G) n.536C>G c.19C>G (n.19C>G) c.179C>G (n.179C>G) c.1386C>G (p.Asn462Lys) c.1485C>G (p.Asn495Lys) c.1437C>G (p.Asn479Lys) c.1431C>G (p.Asn477Lys) c.1332C>G (p.Asn444Lys) c.978C>G (p.Asn326Lys)
1	g.154465311C>T	CA420976011	IL6R	c.1338C>T (p.Asn446=) c.146C>T (n.146C>T) n.536C>T c.19C>T (n.19C>T) c.179C>T (n.179C>T) c.1386C>T (p.Asn462=) c.1485C>T (p.Asn495=) c.1437C>T (p.Asn479=) c.1431C>T (p.Asn477=) c.1332C>T (p.Asn444=) c.978C>T (p.Asn326=)
1	g.154465312C>A	CA420976012	IL6R	c.1339C>A (p.Arg447=) c.147C>A (n.147C>A) n.537C>A c.20C>A (n.20C>A) c.180C>A (n.180C>A) c.1387C>A (p.Arg463=) c.1486C>A (p.Arg496=) c.1438C>A (p.Arg480=) c.1432C>A (p.Arg478=) c.1333C>A (p.Arg445=) c.979C>A (p.Arg327=)
1	g.154465312C=	CA2480880326	IL6R	c.1339C= (p.Arg447=) c.147C= (n.147C=) n.537C= c.20C= (n.20C=) c.180C= (n.180C=) c.1387C= (p.Arg463=) c.1486C= (p.Arg496=) c.1438C= (p.Arg480=) c.1432C= (p.Arg478=) c.1333C= (p.Arg445=) c.979C= (p.Arg327=)
1	g.154465312C>G	CA342628683	IL6R	c.1339C>G (p.Arg447Gly) c.147C>G (n.147C>G) n.537C>G c.20C>G (n.20C>G) c.180C>G (n.180C>G) c.1387C>G (p.Arg463Gly) c.1486C>G (p.Arg496Gly) c.1438C>G (p.Arg480Gly) c.1432C>G (p.Arg478Gly) c.1333C>G (p.Arg445Gly) c.979C>G (p.Arg327Gly)
1	g.154465312C>T	CA1129353	IL6R	c.1339C>T (p.Arg447Ter) c.147C>T (n.147C>T) n.537C>T c.20C>T (n.20C>T) c.180C>T (n.180C>T) c.1387C>T (p.Arg463Ter) c.1486C>T (p.Arg496Ter) c.1438C>T (p.Arg480Ter) c.1432C>T (p.Arg478Ter) c.1333C>T (p.Arg445Ter) c.979C>T (p.Arg327Ter)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465313G>A	CA1129354	IL6R	c.1340G>A (p.Arg447Gln) c.148G>A (n.148G>A) n.538G>A c.21G>A (n.21G>A) c.181G>A (n.181G>A) c.1388G>A (p.Arg463Gln) c.1487G>A (p.Arg496Gln) c.1439G>A (p.Arg480Gln) c.1433G>A (p.Arg478Gln) c.1334G>A (p.Arg445Gln) c.980G>A (p.Arg327Gln)	dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465313G>C	CA342628684	IL6R	c.1340G>C (p.Arg447Pro) c.148G>C (n.148G>C) n.538G>C c.21G>C (n.21G>C) c.181G>C (n.181G>C) c.1388G>C (p.Arg463Pro) c.1487G>C (p.Arg496Pro) c.1439G>C (p.Arg480Pro) c.1433G>C (p.Arg478Pro) c.1334G>C (p.Arg445Pro) c.980G>C (p.Arg327Pro)
1	g.154465313G=	CA2480880327	IL6R	c.1340G= (p.Arg447=) c.148G= (n.148G=) n.538G= c.21G= (n.21G=) c.181G= (n.181G=) c.1388G= (p.Arg463=) c.1487G= (p.Arg496=) c.1439G= (p.Arg480=) c.1433G= (p.Arg478=) c.1334G= (p.Arg445=) c.980G= (p.Arg327=)
1	g.154465313G>T	CA342628685	IL6R	c.1340G>T (p.Arg447Leu) c.148G>T (n.148G>T) n.538G>T c.21G>T (n.21G>T) c.181G>T (n.181G>T) c.1388G>T (p.Arg463Leu) c.1487G>T (p.Arg496Leu) c.1439G>T (p.Arg480Leu) c.1433G>T (p.Arg478Leu) c.1334G>T (p.Arg445Leu) c.980G>T (p.Arg327Leu)	gnomAD v4
1	g.154465314A=	CA2480880328	IL6R	c.1341A= (p.Arg447=) c.149A= (n.149A=) n.539A= c.22A= (n.22A=) c.182A= (n.182A=) c.1389A= (p.Arg463=) c.1488A= (p.Arg496=) c.1440A= (p.Arg480=) c.1434A= (p.Arg478=) c.1335A= (p.Arg445=) c.981A= (p.Arg327=)
1	g.154465314A>C	CA420976014	IL6R	c.1341A>C (p.Arg447=) c.149A>C (n.149A>C) n.539A>C c.22A>C (n.22A>C) c.182A>C (n.182A>C) c.1389A>C (p.Arg463=) c.1488A>C (p.Arg496=) c.1440A>C (p.Arg480=) c.1434A>C (p.Arg478=) c.1335A>C (p.Arg445=) c.981A>C (p.Arg327=)	gnomAD v4
1	g.154465314A>G	CA1129355	IL6R	c.1341A>G (p.Arg447=) c.149A>G (n.149A>G) n.539A>G c.22A>G (n.22A>G) c.182A>G (n.182A>G) c.1389A>G (p.Arg463=) c.1488A>G (p.Arg496=) c.1440A>G (p.Arg480=) c.1434A>G (p.Arg478=) c.1335A>G (p.Arg445=) c.981A>G (p.Arg327=)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465314A>T	CA420976015	IL6R	c.1341A>T (p.Arg447=) c.149A>T (n.149A>T) n.539A>T c.22A>T (n.22A>T) c.182A>T (n.182A>T) c.1389A>T (p.Arg463=) c.1488A>T (p.Arg496=) c.1440A>T (p.Arg480=) c.1434A>T (p.Arg478=) c.1335A>T (p.Arg445=) c.981A>T (p.Arg327=)
1	g.154465315C>A	CA342628686	IL6R	c.1342C>A (p.Pro448Thr) c.150C>A (n.150C>A) c.23C>A (n.23C>A) c.183C>A (n.183C>A) c.1390C>A (p.Pro464Thr) c.1489C>A (p.Pro497Thr) c.1441C>A (p.Pro481Thr) c.1435C>A (p.Pro479Thr) c.1336C>A (p.Pro446Thr) c.982C>A (p.Pro328Thr)	gnomAD v4
1	g.154465315C>G	CA342628687	IL6R	c.1342C>G (p.Pro448Ala) c.150C>G (n.150C>G) c.23C>G (n.23C>G) c.183C>G (n.183C>G) c.1390C>G (p.Pro464Ala) c.1489C>G (p.Pro497Ala) c.1441C>G (p.Pro481Ala) c.1435C>G (p.Pro479Ala) c.1336C>G (p.Pro446Ala) c.982C>G (p.Pro328Ala)
1	g.154465315C>T	CA342628688	IL6R	c.1342C>T (p.Pro448Ser) c.150C>T (n.150C>T) c.23C>T (n.23C>T) c.183C>T (n.183C>T) c.1390C>T (p.Pro464Ser) c.1489C>T (p.Pro497Ser) c.1441C>T (p.Pro481Ser) c.1435C>T (p.Pro479Ser) c.1336C>T (p.Pro446Ser) c.982C>T (p.Pro328Ser)
1	g.154465316C>A	CA342628689	IL6R	c.1343C>A (p.Pro448Gln) c.151C>A (n.151C>A) c.24C>A (n.24C>A) c.184C>A (n.184C>A) c.1391C>A (p.Pro464Gln) c.1490C>A (p.Pro497Gln) c.1442C>A (p.Pro481Gln) c.1436C>A (p.Pro479Gln) c.1337C>A (p.Pro446Gln) c.983C>A (p.Pro328Gln)
1	g.154465316C=	CA2480880329	IL6R	c.1343C= (p.Pro448=) c.151C= (n.151C=) c.24C= (n.24C=) c.184C= (n.184C=) c.1391C= (p.Pro464=) c.1490C= (p.Pro497=) c.1442C= (p.Pro481=) c.1436C= (p.Pro479=) c.1337C= (p.Pro446=) c.983C= (p.Pro328=)
1	g.154465316C>G	CA342628690	IL6R	c.1343C>G (p.Pro448Arg) c.151C>G (n.151C>G) c.24C>G (n.24C>G) c.184C>G (n.184C>G) c.1391C>G (p.Pro464Arg) c.1490C>G (p.Pro497Arg) c.1442C>G (p.Pro481Arg) c.1436C>G (p.Pro479Arg) c.1337C>G (p.Pro446Arg) c.983C>G (p.Pro328Arg)	dbSNP gnomAD v2 gnomAD v4
1	g.154465316C>T	CA342628691	IL6R	c.1343C>T (p.Pro448Leu) c.151C>T (n.151C>T) c.24C>T (n.24C>T) c.184C>T (n.184C>T) c.1391C>T (p.Pro464Leu) c.1490C>T (p.Pro497Leu) c.1442C>T (p.Pro481Leu) c.1436C>T (p.Pro479Leu) c.1337C>T (p.Pro446Leu) c.983C>T (p.Pro328Leu)	gnomAD v4
1	g.154465316_154465317delinsCA	CA2480880330	IL6R	c.1343_1344delinsCA (p.Pro448=) c.151_152delinsCA (n.151_152delinsCA) c.24_25delinsCA (n.24_25delinsCA) c.184_185delinsCA (n.184_185delinsCA) c.1391_1392delinsCA (p.Pro464=) c.1490_1491delinsCA (p.Pro497=) c.1442_1443delinsCA (p.Pro481=) c.1436_1437delinsCA (p.Pro479=) c.1337_1338delinsCA (p.Pro446=) c.983_984delinsCA (p.Pro328=)
1	g.154465317del	CA2480880331	IL6R	c.1344del (p.Asp449MetfsTer?) c.152del (n.152del) c.25del (n.25del) c.185del (n.185del) c.1392del (p.Asp465MetfsTer?) c.1491del (p.Asp498MetfsTer?) c.1443del (p.Asp482MetfsTer?) c.1437del (p.Asp480MetfsTer?) c.1338del (p.Asp447MetfsTer?) c.984del (p.Asp329MetfsTer?)	dbSNP
1	g.154465317A>C	CA420976019	IL6R	c.1344A>C (p.Pro448=) c.152A>C (n.152A>C) c.25A>C (n.25A>C) c.185A>C (n.185A>C) c.1392A>C (p.Pro464=) c.1491A>C (p.Pro497=) c.1443A>C (p.Pro481=) c.1437A>C (p.Pro479=) c.1338A>C (p.Pro446=) c.984A>C (p.Pro328=)
1	g.154465317A>G	CA420976018	IL6R	c.1344A>G (p.Pro448=) c.152A>G (n.152A>G) c.25A>G (n.25A>G) c.185A>G (n.185A>G) c.1392A>G (p.Pro464=) c.1491A>G (p.Pro497=) c.1443A>G (p.Pro481=) c.1437A>G (p.Pro479=) c.1338A>G (p.Pro446=) c.984A>G (p.Pro328=)
1	g.154465317A>T	CA420976017	IL6R	c.1344A>T (p.Pro448=) c.152A>T (n.152A>T) c.25A>T (n.25A>T) c.185A>T (n.185A>T) c.1392A>T (p.Pro464=) c.1491A>T (p.Pro497=) c.1443A>T (p.Pro481=) c.1437A>T (p.Pro479=) c.1338A>T (p.Pro446=) c.984A>T (p.Pro328=)
1	g.154465318G>A	CA342628692	IL6R	c.1345G>A (p.Asp449Asn) c.153G>A (n.153G>A) c.26G>A (n.26G>A) c.186G>A (n.186G>A) c.1393G>A (p.Asp465Asn) c.1492G>A (p.Asp498Asn) c.1444G>A (p.Asp482Asn) c.1438G>A (p.Asp480Asn) c.1339G>A (p.Asp447Asn) c.985G>A (p.Asp329Asn)	gnomAD v4
1	g.154465318G>C	CA342628693	IL6R	c.1345G>C (p.Asp449His) c.153G>C (n.153G>C) c.26G>C (n.26G>C) c.186G>C (n.186G>C) c.1393G>C (p.Asp465His) c.1492G>C (p.Asp498His) c.1444G>C (p.Asp482His) c.1438G>C (p.Asp480His) c.1339G>C (p.Asp447His) c.985G>C (p.Asp329His)
1	g.154465318G>T	CA342628694	IL6R	c.1345G>T (p.Asp449Tyr) c.153G>T (n.153G>T) c.26G>T (n.26G>T) c.186G>T (n.186G>T) c.1393G>T (p.Asp465Tyr) c.1492G>T (p.Asp498Tyr) c.1444G>T (p.Asp482Tyr) c.1438G>T (p.Asp480Tyr) c.1339G>T (p.Asp447Tyr) c.985G>T (p.Asp329Tyr)
1	g.154465319A>C	CA342628697	IL6R	c.1346A>C (p.Asp449Ala) c.154A>C (n.154A>C) c.27A>C (n.27A>C) c.187A>C (n.187A>C) c.1394A>C (p.Asp465Ala) c.1493A>C (p.Asp498Ala) c.1445A>C (p.Asp482Ala) c.1439A>C (p.Asp480Ala) c.1340A>C (p.Asp447Ala) c.986A>C (p.Asp329Ala)
1	g.154465319A>G	CA342628696	IL6R	c.1346A>G (p.Asp449Gly) c.154A>G (n.154A>G) c.27A>G (n.27A>G) c.187A>G (n.187A>G) c.1394A>G (p.Asp465Gly) c.1493A>G (p.Asp498Gly) c.1445A>G (p.Asp482Gly) c.1439A>G (p.Asp480Gly) c.1340A>G (p.Asp447Gly) c.986A>G (p.Asp329Gly)
1	g.154465319A>T	CA342628695	IL6R	c.1346A>T (p.Asp449Val) c.154A>T (n.154A>T) c.27A>T (n.27A>T) c.187A>T (n.187A>T) c.1394A>T (p.Asp465Val) c.1493A>T (p.Asp498Val) c.1445A>T (p.Asp482Val) c.1439A>T (p.Asp480Val) c.1340A>T (p.Asp447Val) c.986A>T (p.Asp329Val)
1	g.154465319_154465320delinsAT	CA2480880332	IL6R	c.1346_1347delinsAT (p.Asp449=) c.154_155delinsAT (n.154_155delinsAT) c.27_28delinsAT (n.27_28delinsAT) c.187_188delinsAT (n.187_188delinsAT) c.1394_1395delinsAT (p.Asp465=) c.1493_1494delinsAT (p.Asp498=) c.1445_1446delinsAT (p.Asp482=) c.1439_1440delinsAT (p.Asp480=) c.1340_1341delinsAT (p.Asp447=) c.986_987delinsAT (p.Asp329=)
1	g.154465320del	CA2480880333	IL6R	c.1347del (p.Asp449GlufsTer?) c.155del (n.155del) c.28del (n.28del) c.188del (n.188del) c.1395del (p.Asp465GlufsTer?) c.1494del (p.Asp498GlufsTer?) c.1446del (p.Asp482GlufsTer?) c.1440del (p.Asp480GlufsTer?) c.1341del (p.Asp447GlufsTer?) c.987del (p.Asp329GlufsTer?)	dbSNP
1	g.154465320T>A	CA342628698	IL6R	c.1347T>A (p.Asp449Glu) c.155T>A (n.155T>A) c.28T>A (n.28T>A) c.188T>A (n.188T>A) c.1395T>A (p.Asp465Glu) c.1494T>A (p.Asp498Glu) c.1446T>A (p.Asp482Glu) c.1440T>A (p.Asp480Glu) c.1341T>A (p.Asp447Glu) c.987T>A (p.Asp329Glu)
1	g.154465320T>C	CA420976020	IL6R	c.1347T>C (p.Asp449=) c.155T>C (n.155T>C) c.28T>C (n.28T>C) c.188T>C (n.188T>C) c.1395T>C (p.Asp465=) c.1494T>C (p.Asp498=) c.1446T>C (p.Asp482=) c.1440T>C (p.Asp480=) c.1341T>C (p.Asp447=) c.987T>C (p.Asp329=)
1	g.154465320T>G	CA342628699	IL6R	c.1347T>G (p.Asp449Glu) c.155T>G (n.155T>G) c.28T>G (n.28T>G) c.188T>G (n.188T>G) c.1395T>G (p.Asp465Glu) c.1494T>G (p.Asp498Glu) c.1446T>G (p.Asp482Glu) c.1440T>G (p.Asp480Glu) c.1341T>G (p.Asp447Glu) c.987T>G (p.Asp329Glu)
1	g.154465321G>A	CA342628700	IL6R	c.1348G>A (p.Ala450Thr) c.156G>A (n.156G>A) c.29G>A (n.29G>A) c.189G>A (n.189G>A) c.1396G>A (p.Ala466Thr) c.1495G>A (p.Ala499Thr) c.1447G>A (p.Ala483Thr) c.1441G>A (p.Ala481Thr) c.1342G>A (p.Ala448Thr) c.988G>A (p.Ala330Thr)
1	g.154465321G>C	CA342628701	IL6R	c.1348G>C (p.Ala450Pro) c.156G>C (n.156G>C) c.29G>C (n.29G>C) c.189G>C (n.189G>C) c.1396G>C (p.Ala466Pro) c.1495G>C (p.Ala499Pro) c.1447G>C (p.Ala483Pro) c.1441G>C (p.Ala481Pro) c.1342G>C (p.Ala448Pro) c.988G>C (p.Ala330Pro)
1	g.154465321G>T	CA342628702	IL6R	c.1348G>T (p.Ala450Ser) c.156G>T (n.156G>T) c.29G>T (n.29G>T) c.189G>T (n.189G>T) c.1396G>T (p.Ala466Ser) c.1495G>T (p.Ala499Ser) c.1447G>T (p.Ala483Ser) c.1441G>T (p.Ala481Ser) c.1342G>T (p.Ala448Ser) c.988G>T (p.Ala330Ser)
1	g.154465324_154465339del	CA2573909651	IL6R	c.1351_1366del (p.Arg451LeufsTer?) c.159_174del (n.159_174del) c.32_47del (n.32_47del) c.192_207del (n.192_207del) c.1399_1414del (p.Arg467LeufsTer?) c.1498_1513del (p.Arg500LeufsTer?) c.1450_1465del (p.Arg484LeufsTer?) c.1444_1459del (p.Arg482LeufsTer?) c.1345_1360del (p.Arg449LeufsTer?) c.991_1006del (p.Arg331LeufsTer?)
1	g.154465322C>A	CA342628703	IL6R	c.1349C>A (p.Ala450Asp) c.157C>A (n.157C>A) c.30C>A (n.30C>A) c.190C>A (n.190C>A) c.1397C>A (p.Ala466Asp) c.1496C>A (p.Ala499Asp) c.1448C>A (p.Ala483Asp) c.1442C>A (p.Ala481Asp) c.1343C>A (p.Ala448Asp) c.989C>A (p.Ala330Asp)
1	g.154465322C>G	CA342628704	IL6R	c.1349C>G (p.Ala450Gly) c.157C>G (n.157C>G) c.30C>G (n.30C>G) c.190C>G (n.190C>G) c.1397C>G (p.Ala466Gly) c.1496C>G (p.Ala499Gly) c.1448C>G (p.Ala483Gly) c.1442C>G (p.Ala481Gly) c.1343C>G (p.Ala448Gly) c.989C>G (p.Ala330Gly)
1	g.154465322C>T	CA342628705	IL6R	c.1349C>T (p.Ala450Val) c.157C>T (n.157C>T) c.30C>T (n.30C>T) c.190C>T (n.190C>T) c.1397C>T (p.Ala466Val) c.1496C>T (p.Ala499Val) c.1448C>T (p.Ala483Val) c.1442C>T (p.Ala481Val) c.1343C>T (p.Ala448Val) c.989C>T (p.Ala330Val)
1	g.154465323C>A	CA420976021	IL6R	c.1350C>A (p.Ala450=) c.158C>A (n.158C>A) c.31C>A (n.31C>A) c.191C>A (n.191C>A) c.1398C>A (p.Ala466=) c.1497C>A (p.Ala499=) c.1449C>A (p.Ala483=) c.1443C>A (p.Ala481=) c.1344C>A (p.Ala448=) c.990C>A (p.Ala330=)
1	g.154465323C=	CA2480880334	IL6R	c.1350C= (p.Ala450=) c.158C= (n.158C=) c.31C= (n.31C=) c.191C= (n.191C=) c.1398C= (p.Ala466=) c.1497C= (p.Ala499=) c.1449C= (p.Ala483=) c.1443C= (p.Ala481=) c.1344C= (p.Ala448=) c.990C= (p.Ala330=)
1	g.154465323C>G	CA420976022	IL6R	c.1350C>G (p.Ala450=) c.158C>G (n.158C>G) c.31C>G (n.31C>G) c.191C>G (n.191C>G) c.1398C>G (p.Ala466=) c.1497C>G (p.Ala499=) c.1449C>G (p.Ala483=) c.1443C>G (p.Ala481=) c.1344C>G (p.Ala448=) c.990C>G (p.Ala330=)	dbSNP gnomAD v2 gnomAD v4
1	g.154465323C>T	CA420976023	IL6R	c.1350C>T (p.Ala450=) c.158C>T (n.158C>T) c.31C>T (n.31C>T) c.191C>T (n.191C>T) c.1398C>T (p.Ala466=) c.1497C>T (p.Ala499=) c.1449C>T (p.Ala483=) c.1443C>T (p.Ala481=) c.1344C>T (p.Ala448=) c.990C>T (p.Ala330=)
1	g.154465324A=	CA1149117317	IL6R	c.1351A= (p.Arg451=) c.159A= (n.159A=) c.32A= (n.32A=) c.192A= (n.192A=) c.1399A= (p.Arg467=) c.1498A= (p.Arg500=) c.1450A= (p.Arg484=) c.1444A= (p.Arg482=) c.1345A= (p.Arg449=) c.991A= (p.Arg331=)
1	g.154465324A>C	CA420976024	IL6R	c.1351A>C (p.Arg451=) c.159A>C (n.159A>C) c.32A>C (n.32A>C) c.192A>C (n.192A>C) c.1399A>C (p.Arg467=) c.1498A>C (p.Arg500=) c.1450A>C (p.Arg484=) c.1444A>C (p.Arg482=) c.1345A>C (p.Arg449=) c.991A>C (p.Arg331=)
1	g.154465324A>G	CA342628706	IL6R	c.1351A>G (p.Arg451Gly) c.159A>G (n.159A>G) c.32A>G (n.32A>G) c.192A>G (n.192A>G) c.1399A>G (p.Arg467Gly) c.1498A>G (p.Arg500Gly) c.1450A>G (p.Arg484Gly) c.1444A>G (p.Arg482Gly) c.1345A>G (p.Arg449Gly) c.991A>G (p.Arg331Gly)
1	g.154465324A>T	CA1129356	IL6R	c.1351A>T (p.Arg451Trp) c.159A>T (n.159A>T) c.32A>T (n.32A>T) c.192A>T (n.192A>T) c.1399A>T (p.Arg467Trp) c.1498A>T (p.Arg500Trp) c.1450A>T (p.Arg484Trp) c.1444A>T (p.Arg482Trp) c.1345A>T (p.Arg449Trp) c.991A>T (p.Arg331Trp)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465325G>A	CA342628707	IL6R	c.1352G>A (p.Arg451Lys) c.160G>A (n.160G>A) c.33G>A (n.33G>A) c.193G>A (n.193G>A) c.1400G>A (p.Arg467Lys) c.1499G>A (p.Arg500Lys) c.1451G>A (p.Arg484Lys) c.1445G>A (p.Arg482Lys) c.1346G>A (p.Arg449Lys) c.992G>A (p.Arg331Lys)
1	g.154465325G>C	CA1129357	IL6R	c.1352G>C (p.Arg451Thr) c.160G>C (n.160G>C) c.33G>C (n.33G>C) c.193G>C (n.193G>C) c.1400G>C (p.Arg467Thr) c.1499G>C (p.Arg500Thr) c.1451G>C (p.Arg484Thr) c.1445G>C (p.Arg482Thr) c.1346G>C (p.Arg449Thr) c.992G>C (p.Arg331Thr)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465325G=	CA1141885200	IL6R	c.1352G= (p.Arg451=) c.160G= (n.160G=) c.33G= (n.33G=) c.193G= (n.193G=) c.1400G= (p.Arg467=) c.1499G= (p.Arg500=) c.1451G= (p.Arg484=) c.1445G= (p.Arg482=) c.1346G= (p.Arg449=) c.992G= (p.Arg331=)
1	g.154465325G>T	CA342628708	IL6R	c.1352G>T (p.Arg451Met) c.160G>T (n.160G>T) c.33G>T (n.33G>T) c.193G>T (n.193G>T) c.1400G>T (p.Arg467Met) c.1499G>T (p.Arg500Met) c.1451G>T (p.Arg484Met) c.1445G>T (p.Arg482Met) c.1346G>T (p.Arg449Met) c.992G>T (p.Arg331Met)
1	g.154465326G>A	CA420976025	IL6R	c.1353G>A (p.Arg451=) c.161G>A (n.161G>A) c.34G>A (n.34G>A) c.194G>A (n.194G>A) c.1401G>A (p.Arg467=) c.1500G>A (p.Arg500=) c.1452G>A (p.Arg484=) c.1446G>A (p.Arg482=) c.1347G>A (p.Arg449=) c.993G>A (p.Arg331=)
1	g.154465326G>C	CA342628709	IL6R	c.1353G>C (p.Arg451Ser) c.161G>C (n.161G>C) c.34G>C (n.34G>C) c.194G>C (n.194G>C) c.1401G>C (p.Arg467Ser) c.1500G>C (p.Arg500Ser) c.1452G>C (p.Arg484Ser) c.1446G>C (p.Arg482Ser) c.1347G>C (p.Arg449Ser) c.993G>C (p.Arg331Ser)
1	g.154465326G>T	CA342628710	IL6R	c.1353G>T (p.Arg451Ser) c.161G>T (n.161G>T) c.34G>T (n.34G>T) c.194G>T (n.194G>T) c.1401G>T (p.Arg467Ser) c.1500G>T (p.Arg500Ser) c.1452G>T (p.Arg484Ser) c.1446G>T (p.Arg482Ser) c.1347G>T (p.Arg449Ser) c.993G>T (p.Arg331Ser)
1	g.154465327G>A	CA342628713	IL6R	c.1354G>A (p.Asp452Asn) c.162G>A (n.162G>A) c.35G>A (n.35G>A) c.195G>A (n.195G>A) c.1402G>A (p.Asp468Asn) c.1501G>A (p.Asp501Asn) c.1453G>A (p.Asp485Asn) c.1447G>A (p.Asp483Asn) c.1348G>A (p.Asp450Asn) c.994G>A (p.Asp332Asn)
1	g.154465327G>C	CA342628712	IL6R	c.1354G>C (p.Asp452His) c.162G>C (n.162G>C) c.35G>C (n.35G>C) c.195G>C (n.195G>C) c.1402G>C (p.Asp468His) c.1501G>C (p.Asp501His) c.1453G>C (p.Asp485His) c.1447G>C (p.Asp483His) c.1348G>C (p.Asp450His) c.994G>C (p.Asp332His)
1	g.154465327G>T	CA342628711	IL6R	c.1354G>T (p.Asp452Tyr) c.162G>T (n.162G>T) c.35G>T (n.35G>T) c.195G>T (n.195G>T) c.1402G>T (p.Asp468Tyr) c.1501G>T (p.Asp501Tyr) c.1453G>T (p.Asp485Tyr) c.1447G>T (p.Asp483Tyr) c.1348G>T (p.Asp450Tyr) c.994G>T (p.Asp332Tyr)
1	g.154465328A>C	CA342628714	IL6R	c.1355A>C (p.Asp452Ala) c.163A>C (n.163A>C) c.36A>C (n.36A>C) c.196A>C (n.196A>C) c.1403A>C (p.Asp468Ala) c.1502A>C (p.Asp501Ala) c.1454A>C (p.Asp485Ala) c.1448A>C (p.Asp483Ala) c.1349A>C (p.Asp450Ala) c.995A>C (p.Asp332Ala)
1	g.154465328A>G	CA342628715	IL6R	c.1355A>G (p.Asp452Gly) c.163A>G (n.163A>G) c.36A>G (n.36A>G) c.196A>G (n.196A>G) c.1403A>G (p.Asp468Gly) c.1502A>G (p.Asp501Gly) c.1454A>G (p.Asp485Gly) c.1448A>G (p.Asp483Gly) c.1349A>G (p.Asp450Gly) c.995A>G (p.Asp332Gly)
1	g.154465328A>T	CA342628716	IL6R	c.1355A>T (p.Asp452Val) c.163A>T (n.163A>T) c.36A>T (n.36A>T) c.196A>T (n.196A>T) c.1403A>T (p.Asp468Val) c.1502A>T (p.Asp501Val) c.1454A>T (p.Asp485Val) c.1448A>T (p.Asp483Val) c.1349A>T (p.Asp450Val) c.995A>T (p.Asp332Val)	gnomAD v4
1	g.154465329C>A	CA342628717	IL6R	c.1356C>A (p.Asp452Glu) c.164C>A (n.164C>A) c.37C>A (n.37C>A) c.197C>A (n.197C>A) c.1404C>A (p.Asp468Glu) c.1503C>A (p.Asp501Glu) c.1455C>A (p.Asp485Glu) c.1449C>A (p.Asp483Glu) c.1350C>A (p.Asp450Glu) c.996C>A (p.Asp332Glu)
1	g.154465329C>G	CA342628718	IL6R	c.1356C>G (p.Asp452Glu) c.164C>G (n.164C>G) c.37C>G (n.37C>G) c.197C>G (n.197C>G) c.1404C>G (p.Asp468Glu) c.1503C>G (p.Asp501Glu) c.1455C>G (p.Asp485Glu) c.1449C>G (p.Asp483Glu) c.1350C>G (p.Asp450Glu) c.996C>G (p.Asp332Glu)
1	g.154465329C>T	CA420976026	IL6R	c.1356C>T (p.Asp452=) c.164C>T (n.164C>T) c.37C>T (n.37C>T) c.197C>T (n.197C>T) c.1404C>T (p.Asp468=) c.1503C>T (p.Asp501=) c.1455C>T (p.Asp485=) c.1449C>T (p.Asp483=) c.1350C>T (p.Asp450=) c.996C>T (p.Asp332=)
1	g.154465330C>A	CA342628719	IL6R	c.1357C>A (p.Pro453Thr) c.165C>A (n.165C>A) c.38C>A (n.38C>A) c.198C>A (n.198C>A) c.1405C>A (p.Pro469Thr) c.1504C>A (p.Pro502Thr) c.1456C>A (p.Pro486Thr) c.1450C>A (p.Pro484Thr) c.1351C>A (p.Pro451Thr) c.997C>A (p.Pro333Thr)
1	g.154465330C>G	CA342628720	IL6R	c.1357C>G (p.Pro453Ala) c.165C>G (n.165C>G) c.38C>G (n.38C>G) c.198C>G (n.198C>G) c.1405C>G (p.Pro469Ala) c.1504C>G (p.Pro502Ala) c.1456C>G (p.Pro486Ala) c.1450C>G (p.Pro484Ala) c.1351C>G (p.Pro451Ala) c.997C>G (p.Pro333Ala)
1	g.154465330C>T	CA342628721	IL6R	c.1357C>T (p.Pro453Ser) c.165C>T (n.165C>T) c.38C>T (n.38C>T) c.198C>T (n.198C>T) c.1405C>T (p.Pro469Ser) c.1504C>T (p.Pro502Ser) c.1456C>T (p.Pro486Ser) c.1450C>T (p.Pro484Ser) c.1351C>T (p.Pro451Ser) c.997C>T (p.Pro333Ser)
1	g.154465331C>A	CA342628722	IL6R	c.1358C>A (p.Pro453Gln) c.166C>A (n.166C>A) c.39C>A (n.39C>A) c.199C>A (n.199C>A) c.1406C>A (p.Pro469Gln) c.1505C>A (p.Pro502Gln) c.1457C>A (p.Pro486Gln) c.1451C>A (p.Pro484Gln) c.1352C>A (p.Pro451Gln) c.998C>A (p.Pro333Gln)
1	g.154465331C>G	CA342628723	IL6R	c.1358C>G (p.Pro453Arg) c.166C>G (n.166C>G) c.39C>G (n.39C>G) c.199C>G (n.199C>G) c.1406C>G (p.Pro469Arg) c.1505C>G (p.Pro502Arg) c.1457C>G (p.Pro486Arg) c.1451C>G (p.Pro484Arg) c.1352C>G (p.Pro451Arg) c.998C>G (p.Pro333Arg)
1	g.154465331C>T	CA342628724	IL6R	c.1358C>T (p.Pro453Leu) c.166C>T (n.166C>T) c.39C>T (n.39C>T) c.199C>T (n.199C>T) c.1406C>T (p.Pro469Leu) c.1505C>T (p.Pro502Leu) c.1457C>T (p.Pro486Leu) c.1451C>T (p.Pro484Leu) c.1352C>T (p.Pro451Leu) c.998C>T (p.Pro333Leu)
1	g.154465332A>C	CA420976027	IL6R	c.1359A>C (p.Pro453=) c.167A>C (n.167A>C) c.40A>C (n.40A>C) c.200A>C (n.200A>C) c.1407A>C (p.Pro469=) c.1506A>C (p.Pro502=) c.1458A>C (p.Pro486=) c.1452A>C (p.Pro484=) c.1353A>C (p.Pro451=) c.999A>C (p.Pro333=)
1	g.154465332A>G	CA420976028	IL6R	c.1359A>G (p.Pro453=) c.167A>G (n.167A>G) c.40A>G (n.40A>G) c.200A>G (n.200A>G) c.1407A>G (p.Pro469=) c.1506A>G (p.Pro502=) c.1458A>G (p.Pro486=) c.1452A>G (p.Pro484=) c.1353A>G (p.Pro451=) c.999A>G (p.Pro333=)
1	g.154465332A>T	CA420976029	IL6R	c.1359A>T (p.Pro453=) c.167A>T (n.167A>T) c.40A>T (n.40A>T) c.200A>T (n.200A>T) c.1407A>T (p.Pro469=) c.1506A>T (p.Pro502=) c.1458A>T (p.Pro486=) c.1452A>T (p.Pro484=) c.1353A>T (p.Pro451=) c.999A>T (p.Pro333=)
1	g.154465333C>A	CA420976030	IL6R	c.1360C>A (p.Arg454=) c.168C>A (n.168C>A) c.41C>A (n.41C>A) c.201C>A (n.201C>A) c.1408C>A (p.Arg470=) c.1507C>A (p.Arg503=) c.1459C>A (p.Arg487=) c.1453C>A (p.Arg485=) c.1354C>A (p.Arg452=) c.1000C>A (p.Arg334=)
1	g.154465333C=	CA2480880335	IL6R	c.1360C= (p.Arg454=) c.168C= (n.168C=) c.41C= (n.41C=) c.201C= (n.201C=) c.1408C= (p.Arg470=) c.1507C= (p.Arg503=) c.1459C= (p.Arg487=) c.1453C= (p.Arg485=) c.1354C= (p.Arg452=) c.1000C= (p.Arg334=)
1	g.154465333C>G	CA342628725	IL6R	c.1360C>G (p.Arg454Gly) c.168C>G (n.168C>G) c.41C>G (n.41C>G) c.201C>G (n.201C>G) c.1408C>G (p.Arg470Gly) c.1507C>G (p.Arg503Gly) c.1459C>G (p.Arg487Gly) c.1453C>G (p.Arg485Gly) c.1354C>G (p.Arg452Gly) c.1000C>G (p.Arg334Gly)
1	g.154465333C>T	CA1129358	IL6R	c.1360C>T (p.Arg454Trp) c.168C>T (n.168C>T) c.41C>T (n.41C>T) c.201C>T (n.201C>T) c.1408C>T (p.Arg470Trp) c.1507C>T (p.Arg503Trp) c.1459C>T (p.Arg487Trp) c.1453C>T (p.Arg485Trp) c.1354C>T (p.Arg452Trp) c.1000C>T (p.Arg334Trp)	ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465334G>A	CA342628727	IL6R	c.1361G>A (p.Arg454Gln) c.169G>A (n.169G>A) c.42G>A (n.42G>A) c.202G>A (n.202G>A) c.1409G>A (p.Arg470Gln) c.1508G>A (p.Arg503Gln) c.1460G>A (p.Arg487Gln) c.1454G>A (p.Arg485Gln) c.1355G>A (p.Arg452Gln) c.1001G>A (p.Arg334Gln)	dbSNP gnomAD v2 gnomAD v4 COSMIC
1	g.154465334G>C	CA342628728	IL6R	c.1361G>C (p.Arg454Pro) c.169G>C (n.169G>C) c.42G>C (n.42G>C) c.202G>C (n.202G>C) c.1409G>C (p.Arg470Pro) c.1508G>C (p.Arg503Pro) c.1460G>C (p.Arg487Pro) c.1454G>C (p.Arg485Pro) c.1355G>C (p.Arg452Pro) c.1001G>C (p.Arg334Pro)
1	g.154465334G=	CA2480880336	IL6R	c.1361G= (p.Arg454=) c.169G= (n.169G=) c.42G= (n.42G=) c.202G= (n.202G=) c.1409G= (p.Arg470=) c.1508G= (p.Arg503=) c.1460G= (p.Arg487=) c.1454G= (p.Arg485=) c.1355G= (p.Arg452=) c.1001G= (p.Arg334=)
1	g.154465334G>T	CA342628726	IL6R	c.1361G>T (p.Arg454Leu) c.169G>T (n.169G>T) c.42G>T (n.42G>T) c.202G>T (n.202G>T) c.1409G>T (p.Arg470Leu) c.1508G>T (p.Arg503Leu) c.1460G>T (p.Arg487Leu) c.1454G>T (p.Arg485Leu) c.1355G>T (p.Arg452Leu) c.1001G>T (p.Arg334Leu)
1	g.154465335G>A	CA420976031	IL6R	c.1362G>A (p.Arg454=) c.170G>A (n.170G>A) c.43G>A (n.43G>A) c.203G>A (n.203G>A) c.1410G>A (p.Arg470=) c.1509G>A (p.Arg503=) c.1461G>A (p.Arg487=) c.1455G>A (p.Arg485=) c.1356G>A (p.Arg452=) c.1002G>A (p.Arg334=)	gnomAD v4
1	g.154465335G>C	CA420976032	IL6R	c.1362G>C (p.Arg454=) c.170G>C (n.170G>C) c.43G>C (n.43G>C) c.203G>C (n.203G>C) c.1410G>C (p.Arg470=) c.1509G>C (p.Arg503=) c.1461G>C (p.Arg487=) c.1455G>C (p.Arg485=) c.1356G>C (p.Arg452=) c.1002G>C (p.Arg334=)
1	g.154465335G>T	CA420976033	IL6R	c.1362G>T (p.Arg454=) c.170G>T (n.170G>T) c.43G>T (n.43G>T) c.203G>T (n.203G>T) c.1410G>T (p.Arg470=) c.1509G>T (p.Arg503=) c.1461G>T (p.Arg487=) c.1455G>T (p.Arg485=) c.1356G>T (p.Arg452=) c.1002G>T (p.Arg334=)
1	g.154465336A>C	CA342628729	IL6R	c.1363A>C (p.Ser455Arg) c.171A>C (n.171A>C) c.44A>C (n.44A>C) c.204A>C (n.204A>C) c.1411A>C (p.Ser471Arg) c.1510A>C (p.Ser504Arg) c.1462A>C (p.Ser488Arg) c.1456A>C (p.Ser486Arg) c.1357A>C (p.Ser453Arg) c.1003A>C (p.Ser335Arg)
1	g.154465336A>G	CA342628730	IL6R	c.1363A>G (p.Ser455Gly) c.171A>G (n.171A>G) c.44A>G (n.44A>G) c.204A>G (n.204A>G) c.1411A>G (p.Ser471Gly) c.1510A>G (p.Ser504Gly) c.1462A>G (p.Ser488Gly) c.1456A>G (p.Ser486Gly) c.1357A>G (p.Ser453Gly) c.1003A>G (p.Ser335Gly)
1	g.154465336A>T	CA342628731	IL6R	c.1363A>T (p.Ser455Cys) c.171A>T (n.171A>T) c.44A>T (n.44A>T) c.204A>T (n.204A>T) c.1411A>T (p.Ser471Cys) c.1510A>T (p.Ser504Cys) c.1462A>T (p.Ser488Cys) c.1456A>T (p.Ser486Cys) c.1357A>T (p.Ser453Cys) c.1003A>T (p.Ser335Cys)
1	g.154465337G>A	CA30816613	IL6R	c.1364G>A (p.Ser455Asn) c.172G>A (n.172G>A) c.45G>A (n.45G>A) c.205G>A (n.205G>A) c.1412G>A (p.Ser471Asn) c.1511G>A (p.Ser504Asn) c.1463G>A (p.Ser488Asn) c.1457G>A (p.Ser486Asn) c.1358G>A (p.Ser453Asn) c.1004G>A (p.Ser335Asn)	dbSNP
1	g.154465337G>C	CA30816622	IL6R	c.1364G>C (p.Ser455Thr) c.172G>C (n.172G>C) c.45G>C (n.45G>C) c.205G>C (n.205G>C) c.1412G>C (p.Ser471Thr) c.1511G>C (p.Ser504Thr) c.1463G>C (p.Ser488Thr) c.1457G>C (p.Ser486Thr) c.1358G>C (p.Ser453Thr) c.1004G>C (p.Ser335Thr)	dbSNP gnomAD v2 gnomAD v4
1	g.154465337G=	CA2480880337	IL6R	c.1364G= (p.Ser455=) c.172G= (n.172G=) c.45G= (n.45G=) c.205G= (n.205G=) c.1412G= (p.Ser471=) c.1511G= (p.Ser504=) c.1463G= (p.Ser488=) c.1457G= (p.Ser486=) c.1358G= (p.Ser453=) c.1004G= (p.Ser335=)
1	g.154465337G>T	CA342628732	IL6R	c.1364G>T (p.Ser455Ile) c.172G>T (n.172G>T) c.45G>T (n.45G>T) c.205G>T (n.205G>T) c.1412G>T (p.Ser471Ile) c.1511G>T (p.Ser504Ile) c.1463G>T (p.Ser488Ile) c.1457G>T (p.Ser486Ile) c.1358G>T (p.Ser453Ile) c.1004G>T (p.Ser335Ile)
1	g.154465338C>A	CA342628733	IL6R	c.1365C>A (p.Ser455Arg) c.173C>A (n.173C>A) c.46C>A (n.46C>A) c.206C>A (n.206C>A) c.1413C>A (p.Ser471Arg) c.1512C>A (p.Ser504Arg) c.1464C>A (p.Ser488Arg) c.1458C>A (p.Ser486Arg) c.1359C>A (p.Ser453Arg) c.1005C>A (p.Ser335Arg)
1	g.154465338C=	CA1143495538	IL6R	c.1365C= (p.Ser455=) c.173C= (n.173C=) c.46C= (n.46C=) c.206C= (n.206C=) c.1413C= (p.Ser471=) c.1512C= (p.Ser504=) c.1464C= (p.Ser488=) c.1458C= (p.Ser486=) c.1359C= (p.Ser453=) c.1005C= (p.Ser335=)
1	g.154465338C>G	CA30816632	IL6R	c.1365C>G (p.Ser455Arg) c.173C>G (n.173C>G) c.46C>G (n.46C>G) c.206C>G (n.206C>G) c.1413C>G (p.Ser471Arg) c.1512C>G (p.Ser504Arg) c.1464C>G (p.Ser488Arg) c.1458C>G (p.Ser486Arg) c.1359C>G (p.Ser453Arg) c.1005C>G (p.Ser335Arg)	ClinVar dbSNP gnomAD v2 gnomAD v3 gnomAD v4
1	g.154465338C>T	CA420976034	IL6R	c.1365C>T (p.Ser455=) c.173C>T (n.173C>T) c.46C>T (n.46C>T) c.206C>T (n.206C>T) c.1413C>T (p.Ser471=) c.1512C>T (p.Ser504=) c.1464C>T (p.Ser488=) c.1458C>T (p.Ser486=) c.1359C>T (p.Ser453=) c.1005C>T (p.Ser335=)
1	g.154465339C>A	CA342628734	IL6R	c.1366C>A (p.Pro456Thr) c.174C>A (n.174C>A) c.47C>A (n.47C>A) c.207C>A (n.207C>A) c.1414C>A (p.Pro472Thr) c.1513C>A (p.Pro505Thr) c.1465C>A (p.Pro489Thr) c.1459C>A (p.Pro487Thr) c.1360C>A (p.Pro454Thr) c.1006C>A (p.Pro336Thr)
1	g.154465339C=	CA2480880338	IL6R	c.1366C= (p.Pro456=) c.174C= (n.174C=) c.47C= (n.47C=) c.207C= (n.207C=) c.1414C= (p.Pro472=) c.1513C= (p.Pro505=) c.1465C= (p.Pro489=) c.1459C= (p.Pro487=) c.1360C= (p.Pro454=) c.1006C= (p.Pro336=)
1	g.154465339C>G	CA342628735	IL6R	c.1366C>G (p.Pro456Ala) c.174C>G (n.174C>G) c.47C>G (n.47C>G) c.207C>G (n.207C>G) c.1414C>G (p.Pro472Ala) c.1513C>G (p.Pro505Ala) c.1465C>G (p.Pro489Ala) c.1459C>G (p.Pro487Ala) c.1360C>G (p.Pro454Ala) c.1006C>G (p.Pro336Ala)
1	g.154465339C>T	CA342628736	IL6R	c.1366C>T (p.Pro456Ser) c.174C>T (n.174C>T) c.47C>T (n.47C>T) c.207C>T (n.207C>T) c.1414C>T (p.Pro472Ser) c.1513C>T (p.Pro505Ser) c.1465C>T (p.Pro489Ser) c.1459C>T (p.Pro487Ser) c.1360C>T (p.Pro454Ser) c.1006C>T (p.Pro336Ser)	dbSNP gnomAD v2 gnomAD v4
1	g.154465340C>A	CA342628739	IL6R	c.1367C>A (p.Pro456His) c.175C>A (n.175C>A) c.48C>A (n.48C>A) c.208C>A (n.208C>A) c.1415C>A (p.Pro472His) c.1514C>A (p.Pro505His) c.1466C>A (p.Pro489His) c.1460C>A (p.Pro487His) c.1361C>A (p.Pro454His) c.1007C>A (p.Pro336His)
1	g.154465340C>G	CA342628738	IL6R	c.1367C>G (p.Pro456Arg) c.175C>G (n.175C>G) c.48C>G (n.48C>G) c.208C>G (n.208C>G) c.1415C>G (p.Pro472Arg) c.1514C>G (p.Pro505Arg) c.1466C>G (p.Pro489Arg) c.1460C>G (p.Pro487Arg) c.1361C>G (p.Pro454Arg) c.1007C>G (p.Pro336Arg)
1	g.154465340C>T	CA342628737	IL6R	c.1367C>T (p.Pro456Leu) c.175C>T (n.175C>T) c.48C>T (n.48C>T) c.208C>T (n.208C>T) c.1415C>T (p.Pro472Leu) c.1514C>T (p.Pro505Leu) c.1466C>T (p.Pro489Leu) c.1460C>T (p.Pro487Leu) c.1361C>T (p.Pro454Leu) c.1007C>T (p.Pro336Leu)
1	g.154465341T>A	CA420976035	IL6R	c.1368T>A (p.Pro456=) c.176T>A (n.176T>A) c.49T>A (n.49T>A) c.209T>A (n.209T>A) c.1416T>A (p.Pro472=) c.1515T>A (p.Pro505=) c.1467T>A (p.Pro489=) c.1461T>A (p.Pro487=) c.1362T>A (p.Pro454=) c.1008T>A (p.Pro336=)
1	g.154465341T>C	CA420976036	IL6R	c.1368T>C (p.Pro456=) c.176T>C (n.176T>C) c.49T>C (n.49T>C) c.209T>C (n.209T>C) c.1416T>C (p.Pro472=) c.1515T>C (p.Pro505=) c.1467T>C (p.Pro489=) c.1461T>C (p.Pro487=) c.1362T>C (p.Pro454=) c.1008T>C (p.Pro336=)
1	g.154465341T>G	CA420976037	IL6R	c.1368T>G (p.Pro456=) c.176T>G (n.176T>G) c.49T>G (n.49T>G) c.209T>G (n.209T>G) c.1416T>G (p.Pro472=) c.1515T>G (p.Pro505=) c.1467T>G (p.Pro489=) c.1461T>G (p.Pro487=) c.1362T>G (p.Pro454=) c.1008T>G (p.Pro336=)
1	g.154465342T>A	CA342628740	IL6R	c.1369T>A (p.Tyr457Asn) c.177T>A (n.177T>A) c.50T>A (n.50T>A) c.210T>A (n.210T>A) c.1417T>A (p.Tyr473Asn) c.1516T>A (p.Tyr506Asn) c.1468T>A (p.Tyr490Asn) c.1462T>A (p.Tyr488Asn) c.1363T>A (p.Tyr455Asn) c.1009T>A (p.Tyr337Asn)
1	g.154465342T>C	CA342628741	IL6R	c.1369T>C (p.Tyr457His) c.177T>C (n.177T>C) c.50T>C (n.50T>C) c.210T>C (n.210T>C) c.1417T>C (p.Tyr473His) c.1516T>C (p.Tyr506His) c.1468T>C (p.Tyr490His) c.1462T>C (p.Tyr488His) c.1363T>C (p.Tyr455His) c.1009T>C (p.Tyr337His)
1	g.154465342T>G	CA342628742	IL6R	c.1369T>G (p.Tyr457Asp) c.177T>G (n.177T>G) c.50T>G (n.50T>G) c.210T>G (n.210T>G) c.1417T>G (p.Tyr473Asp) c.1516T>G (p.Tyr506Asp) c.1468T>G (p.Tyr490Asp) c.1462T>G (p.Tyr488Asp) c.1363T>G (p.Tyr455Asp) c.1009T>G (p.Tyr337Asp)
1	g.154465343A=	CA1148419749	IL6R	c.1370A= (p.Tyr457=) c.178A= (n.178A=) c.51A= (n.51A=) c.211A= (n.211A=) c.1418A= (p.Tyr473=) c.1517A= (p.Tyr506=) c.1469A= (p.Tyr490=) c.1463A= (p.Tyr488=) c.1364A= (p.Tyr455=) c.1010A= (p.Tyr337=)
1	g.154465343A>C	CA1129359	IL6R	c.1370A>C (p.Tyr457Ser) c.178A>C (n.178A>C) c.51A>C (n.51A>C) c.211A>C (n.211A>C) c.1418A>C (p.Tyr473Ser) c.1517A>C (p.Tyr506Ser) c.1469A>C (p.Tyr490Ser) c.1463A>C (p.Tyr488Ser) c.1364A>C (p.Tyr455Ser) c.1010A>C (p.Tyr337Ser)	dbSNP ExAC gnomAD v2 gnomAD v4
1	g.154465343A>G	CA342628743	IL6R	c.1370A>G (p.Tyr457Cys) c.178A>G (n.178A>G) c.51A>G (n.51A>G) c.211A>G (n.211A>G) c.1418A>G (p.Tyr473Cys) c.1517A>G (p.Tyr506Cys) c.1469A>G (p.Tyr490Cys) c.1463A>G (p.Tyr488Cys) c.1364A>G (p.Tyr455Cys) c.1010A>G (p.Tyr337Cys)	gnomAD v4
1	g.154465343A>T	CA342628744	IL6R	c.1370A>T (p.Tyr457Phe) c.178A>T (n.178A>T) c.51A>T (n.51A>T) c.211A>T (n.211A>T) c.1418A>T (p.Tyr473Phe) c.1517A>T (p.Tyr506Phe) c.1469A>T (p.Tyr490Phe) c.1463A>T (p.Tyr488Phe) c.1364A>T (p.Tyr455Phe) c.1010A>T (p.Tyr337Phe)

Number of alleles fetched