Chr Mutation (hg38) CAid Gene Transcript Linkouts
19g.1106357delCA2317520603GPX4c.613-43del (n.613-43del)
c.482-43del (n.482-43del)
c.496-43del (n.496-43del)
c.118-43del (n.118-43del)
c.502-43del (n.502-43del)
c.477-43del (n.477-43del)
c.235-43del (n.235-43del)
c.382-43del (n.382-43del)
c.421-21del (n.421-21del)
n.873-43del
c.421-43del (n.421-43del)
c.499-43del (n.499-43del)
c.610-43del (n.610-43del)
c.502-21del (n.502-21del)
 dbSNP gnomAD v4
19g.1106356C=CA2317520606GPX4c.613-44C= (n.613-44C=)
c.482-44C= (n.482-44C=)
c.496-44C= (n.496-44C=)
c.118-44C= (n.118-44C=)
c.502-44C= (n.502-44C=)
c.477-44C= (n.477-44C=)
c.235-44C= (n.235-44C=)
c.382-44C= (n.382-44C=)
c.421-22C= (n.421-22C=)
n.873-44C=
c.421-44C= (n.421-44C=)
c.499-44C= (n.499-44C=)
c.610-44C= (n.610-44C=)
c.502-22C= (n.502-22C=)
19g.1106356C>TCA783225251GPX4c.613-44C>T (n.613-44C>T)
c.482-44C>T (n.482-44C>T)
c.496-44C>T (n.496-44C>T)
c.118-44C>T (n.118-44C>T)
c.502-44C>T (n.502-44C>T)
c.477-44C>T (n.477-44C>T)
c.235-44C>T (n.235-44C>T)
c.382-44C>T (n.382-44C>T)
c.421-22C>T (n.421-22C>T)
n.873-44C>T
c.421-44C>T (n.421-44C>T)
c.499-44C>T (n.499-44C>T)
c.610-44C>T (n.610-44C>T)
c.502-22C>T (n.502-22C>T)
 dbSNP gnomAD v3 gnomAD v4
19g.1106359T>GCA2576545166GPX4c.613-41T>G (n.613-41T>G)
c.482-41T>G (n.482-41T>G)
c.496-41T>G (n.496-41T>G)
c.118-41T>G (n.118-41T>G)
c.502-41T>G (n.502-41T>G)
c.477-41T>G (n.477-41T>G)
c.235-41T>G (n.235-41T>G)
c.382-41T>G (n.382-41T>G)
c.421-19T>G (n.421-19T>G)
n.873-41T>G
c.421-41T>G (n.421-41T>G)
c.499-41T>G (n.499-41T>G)
c.610-41T>G (n.610-41T>G)
c.502-19T>G (n.502-19T>G)
19g.1106360G>ACA783225252GPX4c.613-40G>A (n.613-40G>A)
c.482-40G>A (n.482-40G>A)
c.496-40G>A (n.496-40G>A)
c.118-40G>A (n.118-40G>A)
c.502-40G>A (n.502-40G>A)
c.477-40G>A (n.477-40G>A)
c.235-40G>A (n.235-40G>A)
c.382-40G>A (n.382-40G>A)
c.421-18G>A (n.421-18G>A)
n.873-40G>A
c.421-40G>A (n.421-40G>A)
c.499-40G>A (n.499-40G>A)
c.610-40G>A (n.610-40G>A)
c.502-18G>A (n.502-18G>A)
 dbSNP
19g.1106360G=CA2317520607GPX4c.613-40G= (n.613-40G=)
c.482-40G= (n.482-40G=)
c.496-40G= (n.496-40G=)
c.118-40G= (n.118-40G=)
c.502-40G= (n.502-40G=)
c.477-40G= (n.477-40G=)
c.235-40G= (n.235-40G=)
c.382-40G= (n.382-40G=)
c.421-18G= (n.421-18G=)
n.873-40G=
c.421-40G= (n.421-40G=)
c.499-40G= (n.499-40G=)
c.610-40G= (n.610-40G=)
c.502-18G= (n.502-18G=)
19g.1106361C=CA2317520608GPX4c.613-39C= (n.613-39C=)
c.482-39C= (n.482-39C=)
c.496-39C= (n.496-39C=)
c.118-39C= (n.118-39C=)
c.502-39C= (n.502-39C=)
c.477-39C= (n.477-39C=)
c.235-39C= (n.235-39C=)
c.382-39C= (n.382-39C=)
c.421-17C= (n.421-17C=)
n.873-39C=
c.421-39C= (n.421-39C=)
c.499-39C= (n.499-39C=)
c.610-39C= (n.610-39C=)
c.502-17C= (n.502-17C=)
19g.1106361C>TCA9037446GPX4c.613-39C>T (n.613-39C>T)
c.482-39C>T (n.482-39C>T)
c.496-39C>T (n.496-39C>T)
c.118-39C>T (n.118-39C>T)
c.502-39C>T (n.502-39C>T)
c.477-39C>T (n.477-39C>T)
c.235-39C>T (n.235-39C>T)
c.382-39C>T (n.382-39C>T)
c.421-17C>T (n.421-17C>T)
n.873-39C>T
c.421-39C>T (n.421-39C>T)
c.499-39C>T (n.499-39C>T)
c.610-39C>T (n.610-39C>T)
c.502-17C>T (n.502-17C>T)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106363G>ACA2588207834GPX4c.613-37G>A (n.613-37G>A)
c.482-37G>A (n.482-37G>A)
c.496-37G>A (n.496-37G>A)
c.118-37G>A (n.118-37G>A)
c.502-37G>A (n.502-37G>A)
c.477-37G>A (n.477-37G>A)
c.235-37G>A (n.235-37G>A)
c.382-37G>A (n.382-37G>A)
c.421-15G>A (n.421-15G>A)
n.873-37G>A
c.421-37G>A (n.421-37G>A)
c.499-37G>A (n.499-37G>A)
c.610-37G>A (n.610-37G>A)
c.502-15G>A (n.502-15G>A)
 gnomAD v4
19g.1106364G>ACA631298708GPX4c.613-36G>A (n.613-36G>A)
c.482-36G>A (n.482-36G>A)
c.496-36G>A (n.496-36G>A)
c.118-36G>A (n.118-36G>A)
c.502-36G>A (n.502-36G>A)
c.477-36G>A (n.477-36G>A)
c.235-36G>A (n.235-36G>A)
c.382-36G>A (n.382-36G>A)
c.421-14G>A (n.421-14G>A)
n.873-36G>A
c.421-36G>A (n.421-36G>A)
c.499-36G>A (n.499-36G>A)
c.610-36G>A (n.610-36G>A)
c.502-14G>A (n.502-14G>A)
 dbSNP gnomAD v2 gnomAD v4
19g.1106364G=CA2317520609GPX4c.613-36G= (n.613-36G=)
c.482-36G= (n.482-36G=)
c.496-36G= (n.496-36G=)
c.118-36G= (n.118-36G=)
c.502-36G= (n.502-36G=)
c.477-36G= (n.477-36G=)
c.235-36G= (n.235-36G=)
c.382-36G= (n.382-36G=)
c.421-14G= (n.421-14G=)
n.873-36G=
c.421-36G= (n.421-36G=)
c.499-36G= (n.499-36G=)
c.610-36G= (n.610-36G=)
c.502-14G= (n.502-14G=)
19g.1106365G>ACA9037447GPX4c.613-35G>A (n.613-35G>A)
c.482-35G>A (n.482-35G>A)
c.496-35G>A (n.496-35G>A)
c.118-35G>A (n.118-35G>A)
c.502-35G>A (n.502-35G>A)
c.477-35G>A (n.477-35G>A)
c.235-35G>A (n.235-35G>A)
c.382-35G>A (n.382-35G>A)
c.421-13G>A (n.421-13G>A)
n.873-35G>A
c.421-35G>A (n.421-35G>A)
c.499-35G>A (n.499-35G>A)
c.610-35G>A (n.610-35G>A)
c.502-13G>A (n.502-13G>A)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106365G>CCA631298709GPX4c.613-35G>C (n.613-35G>C)
c.482-35G>C (n.482-35G>C)
c.496-35G>C (n.496-35G>C)
c.118-35G>C (n.118-35G>C)
c.502-35G>C (n.502-35G>C)
c.477-35G>C (n.477-35G>C)
c.235-35G>C (n.235-35G>C)
c.382-35G>C (n.382-35G>C)
c.421-13G>C (n.421-13G>C)
n.873-35G>C
c.421-35G>C (n.421-35G>C)
c.499-35G>C (n.499-35G>C)
c.610-35G>C (n.610-35G>C)
c.502-13G>C (n.502-13G>C)
 dbSNP gnomAD v2 gnomAD v4
19g.1106365G=CA2317520610GPX4c.613-35G= (n.613-35G=)
c.482-35G= (n.482-35G=)
c.496-35G= (n.496-35G=)
c.118-35G= (n.118-35G=)
c.502-35G= (n.502-35G=)
c.477-35G= (n.477-35G=)
c.235-35G= (n.235-35G=)
c.382-35G= (n.382-35G=)
c.421-13G= (n.421-13G=)
n.873-35G=
c.421-35G= (n.421-35G=)
c.499-35G= (n.499-35G=)
c.610-35G= (n.610-35G=)
c.502-13G= (n.502-13G=)
19g.1106366G>ACA2588207835GPX4c.613-34G>A (n.613-34G>A)
c.482-34G>A (n.482-34G>A)
c.496-34G>A (n.496-34G>A)
c.118-34G>A (n.118-34G>A)
c.502-34G>A (n.502-34G>A)
c.477-34G>A (n.477-34G>A)
c.235-34G>A (n.235-34G>A)
c.382-34G>A (n.382-34G>A)
c.421-12G>A (n.421-12G>A)
n.873-34G>A
c.421-34G>A (n.421-34G>A)
c.499-34G>A (n.499-34G>A)
c.610-34G>A (n.610-34G>A)
c.502-12G>A (n.502-12G>A)
 gnomAD v4
19g.1106366G>CCA2588207836GPX4c.613-34G>C (n.613-34G>C)
c.482-34G>C (n.482-34G>C)
c.496-34G>C (n.496-34G>C)
c.118-34G>C (n.118-34G>C)
c.502-34G>C (n.502-34G>C)
c.477-34G>C (n.477-34G>C)
c.235-34G>C (n.235-34G>C)
c.382-34G>C (n.382-34G>C)
c.421-12G>C (n.421-12G>C)
n.873-34G>C
c.421-34G>C (n.421-34G>C)
c.499-34G>C (n.499-34G>C)
c.610-34G>C (n.610-34G>C)
c.502-12G>C (n.502-12G>C)
 gnomAD v4
19g.1106367T>CCA2317520612GPX4c.613-33T>C (n.613-33T>C)
c.482-33T>C (n.482-33T>C)
c.496-33T>C (n.496-33T>C)
c.118-33T>C (n.118-33T>C)
c.502-33T>C (n.502-33T>C)
c.477-33T>C (n.477-33T>C)
c.235-33T>C (n.235-33T>C)
c.382-33T>C (n.382-33T>C)
c.421-11T>C (n.421-11T>C)
n.873-33T>C
c.421-33T>C (n.421-33T>C)
c.499-33T>C (n.499-33T>C)
c.610-33T>C (n.610-33T>C)
c.502-11T>C (n.502-11T>C)
 dbSNP
19g.1106367T>GCA2588207837GPX4c.613-33T>G (n.613-33T>G)
c.482-33T>G (n.482-33T>G)
c.496-33T>G (n.496-33T>G)
c.118-33T>G (n.118-33T>G)
c.502-33T>G (n.502-33T>G)
c.477-33T>G (n.477-33T>G)
c.235-33T>G (n.235-33T>G)
c.382-33T>G (n.382-33T>G)
c.421-11T>G (n.421-11T>G)
n.873-33T>G
c.421-33T>G (n.421-33T>G)
c.499-33T>G (n.499-33T>G)
c.610-33T>G (n.610-33T>G)
c.502-11T>G (n.502-11T>G)
 gnomAD v4
19g.1106367T=CA2317520611GPX4c.613-33T= (n.613-33T=)
c.482-33T= (n.482-33T=)
c.496-33T= (n.496-33T=)
c.118-33T= (n.118-33T=)
c.502-33T= (n.502-33T=)
c.477-33T= (n.477-33T=)
c.235-33T= (n.235-33T=)
c.382-33T= (n.382-33T=)
c.421-11T= (n.421-11T=)
n.873-33T=
c.421-33T= (n.421-33T=)
c.499-33T= (n.499-33T=)
c.610-33T= (n.610-33T=)
c.502-11T= (n.502-11T=)
19g.1106368G>ACA9037448GPX4c.613-32G>A (n.613-32G>A)
c.482-32G>A (n.482-32G>A)
c.496-32G>A (n.496-32G>A)
c.118-32G>A (n.118-32G>A)
c.502-32G>A (n.502-32G>A)
c.477-32G>A (n.477-32G>A)
c.235-32G>A (n.235-32G>A)
c.382-32G>A (n.382-32G>A)
c.421-10G>A (n.421-10G>A)
n.873-32G>A
c.421-32G>A (n.421-32G>A)
c.499-32G>A (n.499-32G>A)
c.610-32G>A (n.610-32G>A)
c.502-10G>A (n.502-10G>A)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106368G=CA2317520613GPX4c.613-32G= (n.613-32G=)
c.482-32G= (n.482-32G=)
c.496-32G= (n.496-32G=)
c.118-32G= (n.118-32G=)
c.502-32G= (n.502-32G=)
c.477-32G= (n.477-32G=)
c.235-32G= (n.235-32G=)
c.382-32G= (n.382-32G=)
c.421-10G= (n.421-10G=)
n.873-32G=
c.421-32G= (n.421-32G=)
c.499-32G= (n.499-32G=)
c.610-32G= (n.610-32G=)
c.502-10G= (n.502-10G=)
19g.1106369G>ACA2576545167GPX4c.613-31G>A (n.613-31G>A)
c.482-31G>A (n.482-31G>A)
c.496-31G>A (n.496-31G>A)
c.118-31G>A (n.118-31G>A)
c.502-31G>A (n.502-31G>A)
c.477-31G>A (n.477-31G>A)
c.235-31G>A (n.235-31G>A)
c.382-31G>A (n.382-31G>A)
c.421-9G>A (n.421-9G>A)
n.873-31G>A
c.421-31G>A (n.421-31G>A)
c.499-31G>A (n.499-31G>A)
c.610-31G>A (n.610-31G>A)
c.502-9G>A (n.502-9G>A)
 gnomAD v4
19g.1106369G>CCA2588207838GPX4c.613-31G>C (n.613-31G>C)
c.482-31G>C (n.482-31G>C)
c.496-31G>C (n.496-31G>C)
c.118-31G>C (n.118-31G>C)
c.502-31G>C (n.502-31G>C)
c.477-31G>C (n.477-31G>C)
c.235-31G>C (n.235-31G>C)
c.382-31G>C (n.382-31G>C)
c.421-9G>C (n.421-9G>C)
n.873-31G>C
c.421-31G>C (n.421-31G>C)
c.499-31G>C (n.499-31G>C)
c.610-31G>C (n.610-31G>C)
c.502-9G>C (n.502-9G>C)
 gnomAD v4
19g.1106369G=CA2317520614GPX4c.613-31G= (n.613-31G=)
c.482-31G= (n.482-31G=)
c.496-31G= (n.496-31G=)
c.118-31G= (n.118-31G=)
c.502-31G= (n.502-31G=)
c.477-31G= (n.477-31G=)
c.235-31G= (n.235-31G=)
c.382-31G= (n.382-31G=)
c.421-9G= (n.421-9G=)
n.873-31G=
c.421-31G= (n.421-31G=)
c.499-31G= (n.499-31G=)
c.610-31G= (n.610-31G=)
c.502-9G= (n.502-9G=)
19g.1106369G>TCA2317520615GPX4c.613-31G>T (n.613-31G>T)
c.482-31G>T (n.482-31G>T)
c.496-31G>T (n.496-31G>T)
c.118-31G>T (n.118-31G>T)
c.502-31G>T (n.502-31G>T)
c.477-31G>T (n.477-31G>T)
c.235-31G>T (n.235-31G>T)
c.382-31G>T (n.382-31G>T)
c.421-9G>T (n.421-9G>T)
n.873-31G>T
c.421-31G>T (n.421-31G>T)
c.499-31G>T (n.499-31G>T)
c.610-31G>T (n.610-31G>T)
c.502-9G>T (n.502-9G>T)
 dbSNP gnomAD v4
19g.1106370C=CA2317520616GPX4c.613-30C= (n.613-30C=)
c.482-30C= (n.482-30C=)
c.496-30C= (n.496-30C=)
c.118-30C= (n.118-30C=)
c.502-30C= (n.502-30C=)
c.477-30C= (n.477-30C=)
c.235-30C= (n.235-30C=)
c.382-30C= (n.382-30C=)
c.421-8C= (n.421-8C=)
n.873-30C=
c.421-30C= (n.421-30C=)
c.499-30C= (n.499-30C=)
c.610-30C= (n.610-30C=)
c.502-8C= (n.502-8C=)
19g.1106370C>TCA9037449GPX4c.613-30C>T (n.613-30C>T)
c.482-30C>T (n.482-30C>T)
c.496-30C>T (n.496-30C>T)
c.118-30C>T (n.118-30C>T)
c.502-30C>T (n.502-30C>T)
c.477-30C>T (n.477-30C>T)
c.235-30C>T (n.235-30C>T)
c.382-30C>T (n.382-30C>T)
c.421-8C>T (n.421-8C>T)
n.873-30C>T
c.421-30C>T (n.421-30C>T)
c.499-30C>T (n.499-30C>T)
c.610-30C>T (n.610-30C>T)
c.502-8C>T (n.502-8C>T)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106373dupCA2813238541GPX4c.613-27dup (n.613-27dup)
c.482-27dup (n.482-27dup)
c.496-27dup (n.496-27dup)
c.118-27dup (n.118-27dup)
c.502-27dup (n.502-27dup)
c.477-27dup (n.477-27dup)
c.235-27dup (n.235-27dup)
c.382-27dup (n.382-27dup)
c.421-5dup (n.421-5dup)
n.873-27dup
c.421-27dup (n.421-27dup)
c.499-27dup (n.499-27dup)
c.610-27dup (n.610-27dup)
c.502-5dup (n.502-5dup)
19g.1106371C>ACA2576545168GPX4c.613-29C>A (n.613-29C>A)
c.482-29C>A (n.482-29C>A)
c.496-29C>A (n.496-29C>A)
c.118-29C>A (n.118-29C>A)
c.502-29C>A (n.502-29C>A)
c.477-29C>A (n.477-29C>A)
c.235-29C>A (n.235-29C>A)
c.382-29C>A (n.382-29C>A)
c.421-7C>A (n.421-7C>A)
n.873-29C>A
c.421-29C>A (n.421-29C>A)
c.499-29C>A (n.499-29C>A)
c.610-29C>A (n.610-29C>A)
c.502-7C>A (n.502-7C>A)
19g.1106371C=CA2317520617GPX4c.613-29C= (n.613-29C=)
c.482-29C= (n.482-29C=)
c.496-29C= (n.496-29C=)
c.118-29C= (n.118-29C=)
c.502-29C= (n.502-29C=)
c.477-29C= (n.477-29C=)
c.235-29C= (n.235-29C=)
c.382-29C= (n.382-29C=)
c.421-7C= (n.421-7C=)
n.873-29C=
c.421-29C= (n.421-29C=)
c.499-29C= (n.499-29C=)
c.610-29C= (n.610-29C=)
c.502-7C= (n.502-7C=)
19g.1106371C>TCA783225261GPX4c.613-29C>T (n.613-29C>T)
c.482-29C>T (n.482-29C>T)
c.496-29C>T (n.496-29C>T)
c.118-29C>T (n.118-29C>T)
c.502-29C>T (n.502-29C>T)
c.477-29C>T (n.477-29C>T)
c.235-29C>T (n.235-29C>T)
c.382-29C>T (n.382-29C>T)
c.421-7C>T (n.421-7C>T)
n.873-29C>T
c.421-29C>T (n.421-29C>T)
c.499-29C>T (n.499-29C>T)
c.610-29C>T (n.610-29C>T)
c.502-7C>T (n.502-7C>T)
 dbSNP gnomAD v4
19g.1106372C=CA2317520618GPX4c.613-28C= (n.613-28C=)
c.482-28C= (n.482-28C=)
c.496-28C= (n.496-28C=)
c.118-28C= (n.118-28C=)
c.502-28C= (n.502-28C=)
c.477-28C= (n.477-28C=)
c.235-28C= (n.235-28C=)
c.382-28C= (n.382-28C=)
c.421-6C= (n.421-6C=)
n.873-28C=
c.421-28C= (n.421-28C=)
c.499-28C= (n.499-28C=)
c.610-28C= (n.610-28C=)
c.502-6C= (n.502-6C=)
19g.1106372C>GCA631298711GPX4c.613-28C>G (n.613-28C>G)
c.482-28C>G (n.482-28C>G)
c.496-28C>G (n.496-28C>G)
c.118-28C>G (n.118-28C>G)
c.502-28C>G (n.502-28C>G)
c.477-28C>G (n.477-28C>G)
c.235-28C>G (n.235-28C>G)
c.382-28C>G (n.382-28C>G)
c.421-6C>G (n.421-6C>G)
n.873-28C>G
c.421-28C>G (n.421-28C>G)
c.499-28C>G (n.499-28C>G)
c.610-28C>G (n.610-28C>G)
c.502-6C>G (n.502-6C>G)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
19g.1106372C>TCA9037450GPX4c.613-28C>T (n.613-28C>T)
c.482-28C>T (n.482-28C>T)
c.496-28C>T (n.496-28C>T)
c.118-28C>T (n.118-28C>T)
c.502-28C>T (n.502-28C>T)
c.477-28C>T (n.477-28C>T)
c.235-28C>T (n.235-28C>T)
c.382-28C>T (n.382-28C>T)
c.421-6C>T (n.421-6C>T)
n.873-28C>T
c.421-28C>T (n.421-28C>T)
c.499-28C>T (n.499-28C>T)
c.610-28C>T (n.610-28C>T)
c.502-6C>T (n.502-6C>T)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106372_1106374delinsCCACA2317520619GPX4c.613-28_613-26delinsCCA (n.613-28_613-26delinsCCA)
c.482-28_482-26delinsCCA (n.482-28_482-26delinsCCA)
c.496-28_496-26delinsCCA (n.496-28_496-26delinsCCA)
c.118-28_118-26delinsCCA (n.118-28_118-26delinsCCA)
c.502-28_502-26delinsCCA (n.502-28_502-26delinsCCA)
c.477-28_477-26delinsCCA (n.477-28_477-26delinsCCA)
c.235-28_235-26delinsCCA (n.235-28_235-26delinsCCA)
c.382-28_382-26delinsCCA (n.382-28_382-26delinsCCA)
c.421-6_421-4delinsCCA (n.421-6_421-4delinsCCA)
n.873-28_873-26delinsCCA
c.421-28_421-26delinsCCA (n.421-28_421-26delinsCCA)
c.499-28_499-26delinsCCA (n.499-28_499-26delinsCCA)
c.610-28_610-26delinsCCA (n.610-28_610-26delinsCCA)
c.502-6_502-4delinsCCA (n.502-6_502-4delinsCCA)
19g.1106373C=CA2317520620GPX4c.613-27C= (n.613-27C=)
c.482-27C= (n.482-27C=)
c.496-27C= (n.496-27C=)
c.118-27C= (n.118-27C=)
c.502-27C= (n.502-27C=)
c.477-27C= (n.477-27C=)
c.235-27C= (n.235-27C=)
c.382-27C= (n.382-27C=)
c.421-5C= (n.421-5C=)
n.873-27C=
c.421-27C= (n.421-27C=)
c.499-27C= (n.499-27C=)
c.610-27C= (n.610-27C=)
c.502-5C= (n.502-5C=)
19g.1106373C>TCA9037451GPX4c.613-27C>T (n.613-27C>T)
c.482-27C>T (n.482-27C>T)
c.496-27C>T (n.496-27C>T)
c.118-27C>T (n.118-27C>T)
c.502-27C>T (n.502-27C>T)
c.477-27C>T (n.477-27C>T)
c.235-27C>T (n.235-27C>T)
c.382-27C>T (n.382-27C>T)
c.421-5C>T (n.421-5C>T)
n.873-27C>T
c.421-27C>T (n.421-27C>T)
c.499-27C>T (n.499-27C>T)
c.610-27C>T (n.610-27C>T)
c.502-5C>T (n.502-5C>T)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106375_1106376delCA631298713GPX4c.613-25_613-24del (n.613-25_613-24del)
c.482-25_482-24del (n.482-25_482-24del)
c.496-25_496-24del (n.496-25_496-24del)
c.118-25_118-24del (n.118-25_118-24del)
c.502-25_502-24del (n.502-25_502-24del)
c.477-25_477-24del (n.477-25_477-24del)
c.235-25_235-24del (n.235-25_235-24del)
c.382-25_382-24del (n.382-25_382-24del)
c.421-3_421-2del (n.421-3_421-2del)
n.873-25_873-24del
c.421-25_421-24del (n.421-25_421-24del)
c.499-25_499-24del (n.499-25_499-24del)
c.610-25_610-24del (n.610-25_610-24del)
c.502-3_502-2del (n.502-3_502-2del)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
19g.1106374A>GCA2588207839GPX4c.613-26A>G (n.613-26A>G)
c.482-26A>G (n.482-26A>G)
c.496-26A>G (n.496-26A>G)
c.118-26A>G (n.118-26A>G)
c.502-26A>G (n.502-26A>G)
c.477-26A>G (n.477-26A>G)
c.235-26A>G (n.235-26A>G)
c.382-26A>G (n.382-26A>G)
c.421-4A>G (n.421-4A>G)
n.873-26A>G
c.421-26A>G (n.421-26A>G)
c.499-26A>G (n.499-26A>G)
c.610-26A>G (n.610-26A>G)
c.502-4A>G (n.502-4A>G)
 gnomAD v4
19g.1106375C>ACA2588207840GPX4c.613-25C>A (n.613-25C>A)
c.482-25C>A (n.482-25C>A)
c.496-25C>A (n.496-25C>A)
c.118-25C>A (n.118-25C>A)
c.502-25C>A (n.502-25C>A)
c.477-25C>A (n.477-25C>A)
c.235-25C>A (n.235-25C>A)
c.382-25C>A (n.382-25C>A)
c.421-3C>A (n.421-3C>A)
n.873-25C>A
c.421-25C>A (n.421-25C>A)
c.499-25C>A (n.499-25C>A)
c.610-25C>A (n.610-25C>A)
c.502-3C>A (n.502-3C>A)
 gnomAD v4
19g.1106375C=CA2317520621GPX4c.613-25C= (n.613-25C=)
c.482-25C= (n.482-25C=)
c.496-25C= (n.496-25C=)
c.118-25C= (n.118-25C=)
c.502-25C= (n.502-25C=)
c.477-25C= (n.477-25C=)
c.235-25C= (n.235-25C=)
c.382-25C= (n.382-25C=)
c.421-3C= (n.421-3C=)
n.873-25C=
c.421-25C= (n.421-25C=)
c.499-25C= (n.499-25C=)
c.610-25C= (n.610-25C=)
c.502-3C= (n.502-3C=)
19g.1106375C>TCA9037452GPX4c.613-25C>T (n.613-25C>T)
c.482-25C>T (n.482-25C>T)
c.496-25C>T (n.496-25C>T)
c.118-25C>T (n.118-25C>T)
c.502-25C>T (n.502-25C>T)
c.477-25C>T (n.477-25C>T)
c.235-25C>T (n.235-25C>T)
c.382-25C>T (n.382-25C>T)
c.421-3C>T (n.421-3C>T)
n.873-25C>T
c.421-25C>T (n.421-25C>T)
c.499-25C>T (n.499-25C>T)
c.610-25C>T (n.610-25C>T)
c.502-3C>T (n.502-3C>T)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106376A=CA2317520622GPX4c.613-24A= (n.613-24A=)
c.482-24A= (n.482-24A=)
c.496-24A= (n.496-24A=)
c.118-24A= (n.118-24A=)
c.502-24A= (n.502-24A=)
c.477-24A= (n.477-24A=)
c.235-24A= (n.235-24A=)
c.382-24A= (n.382-24A=)
c.421-2A= (n.421-2A=)
n.873-24A=
c.421-24A= (n.421-24A=)
c.499-24A= (n.499-24A=)
c.610-24A= (n.610-24A=)
c.502-2A= (n.502-2A=)
19g.1106376A>CCA402939418GPX4c.613-24A>C (n.613-24A>C)
c.482-24A>C (n.482-24A>C)
c.496-24A>C (n.496-24A>C)
c.118-24A>C (n.118-24A>C)
c.502-24A>C (n.502-24A>C)
c.477-24A>C (n.477-24A>C)
c.235-24A>C (n.235-24A>C)
c.382-24A>C (n.382-24A>C)
c.421-2A>C (n.421-2A>C)
n.873-24A>C
c.421-24A>C (n.421-24A>C)
c.499-24A>C (n.499-24A>C)
c.610-24A>C (n.610-24A>C)
c.502-2A>C (n.502-2A>C)
19g.1106376A>GCA9037453GPX4c.613-24A>G (n.613-24A>G)
c.482-24A>G (n.482-24A>G)
c.496-24A>G (n.496-24A>G)
c.118-24A>G (n.118-24A>G)
c.502-24A>G (n.502-24A>G)
c.477-24A>G (n.477-24A>G)
c.235-24A>G (n.235-24A>G)
c.382-24A>G (n.382-24A>G)
c.421-2A>G (n.421-2A>G)
n.873-24A>G
c.421-24A>G (n.421-24A>G)
c.499-24A>G (n.499-24A>G)
c.610-24A>G (n.610-24A>G)
c.502-2A>G (n.502-2A>G)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106376A>TCA402939423GPX4c.613-24A>T (n.613-24A>T)
c.482-24A>T (n.482-24A>T)
c.496-24A>T (n.496-24A>T)
c.118-24A>T (n.118-24A>T)
c.502-24A>T (n.502-24A>T)
c.477-24A>T (n.477-24A>T)
c.235-24A>T (n.235-24A>T)
c.382-24A>T (n.382-24A>T)
c.421-2A>T (n.421-2A>T)
n.873-24A>T
c.421-24A>T (n.421-24A>T)
c.499-24A>T (n.499-24A>T)
c.610-24A>T (n.610-24A>T)
c.502-2A>T (n.502-2A>T)
 gnomAD v4
19g.1106377G>ACA402939435GPX4c.613-23G>A (n.613-23G>A)
c.482-23G>A (n.482-23G>A)
c.496-23G>A (n.496-23G>A)
c.118-23G>A (n.118-23G>A)
c.502-23G>A (n.502-23G>A)
c.477-23G>A (n.477-23G>A)
c.235-23G>A (n.235-23G>A)
c.382-23G>A (n.382-23G>A)
c.421-1G>A (n.421-1G>A)
n.873-23G>A
c.421-23G>A (n.421-23G>A)
c.499-23G>A (n.499-23G>A)
c.610-23G>A (n.610-23G>A)
c.502-1G>A (n.502-1G>A)
19g.1106377G>CCA402939430GPX4c.613-23G>C (n.613-23G>C)
c.482-23G>C (n.482-23G>C)
c.496-23G>C (n.496-23G>C)
c.118-23G>C (n.118-23G>C)
c.502-23G>C (n.502-23G>C)
c.477-23G>C (n.477-23G>C)
c.235-23G>C (n.235-23G>C)
c.382-23G>C (n.382-23G>C)
c.421-1G>C (n.421-1G>C)
n.873-23G>C
c.421-23G>C (n.421-23G>C)
c.499-23G>C (n.499-23G>C)
c.610-23G>C (n.610-23G>C)
c.502-1G>C (n.502-1G>C)
19g.1106377G>TCA402939426GPX4c.613-23G>T (n.613-23G>T)
c.482-23G>T (n.482-23G>T)
c.496-23G>T (n.496-23G>T)
c.118-23G>T (n.118-23G>T)
c.502-23G>T (n.502-23G>T)
c.477-23G>T (n.477-23G>T)
c.235-23G>T (n.235-23G>T)
c.382-23G>T (n.382-23G>T)
c.421-1G>T (n.421-1G>T)
n.873-23G>T
c.421-23G>T (n.421-23G>T)
c.499-23G>T (n.499-23G>T)
c.610-23G>T (n.610-23G>T)
c.502-1G>T (n.502-1G>T)
19g.1106378T>ACA402939439GPX4c.613-22T>A (n.613-22T>A)
c.482-22T>A (n.482-22T>A)
c.496-22T>A (n.496-22T>A)
c.118-22T>A (n.118-22T>A)
c.502-22T>A (n.502-22T>A)
c.477-22T>A (n.477-22T>A)
c.235-22T>A (n.235-22T>A)
c.382-22T>A (n.382-22T>A)
c.421T>A (p.Phe141Ile)
n.873-22T>A
c.421-22T>A (n.421-22T>A)
c.499-22T>A (n.499-22T>A)
c.610-22T>A (n.610-22T>A)
c.502T>A (p.Phe168Ile)
19g.1106378T>CCA402939442GPX4c.613-22T>C (n.613-22T>C)
c.482-22T>C (n.482-22T>C)
c.496-22T>C (n.496-22T>C)
c.118-22T>C (n.118-22T>C)
c.502-22T>C (n.502-22T>C)
c.477-22T>C (n.477-22T>C)
c.235-22T>C (n.235-22T>C)
c.382-22T>C (n.382-22T>C)
c.421T>C (p.Phe141Leu)
n.873-22T>C
c.421-22T>C (n.421-22T>C)
c.499-22T>C (n.499-22T>C)
c.610-22T>C (n.610-22T>C)
c.502T>C (p.Phe168Leu)
19g.1106378T>GCA402939446GPX4c.613-22T>G (n.613-22T>G)
c.482-22T>G (n.482-22T>G)
c.496-22T>G (n.496-22T>G)
c.118-22T>G (n.118-22T>G)
c.502-22T>G (n.502-22T>G)
c.477-22T>G (n.477-22T>G)
c.235-22T>G (n.235-22T>G)
c.382-22T>G (n.382-22T>G)
c.421T>G (p.Phe141Val)
n.873-22T>G
c.421-22T>G (n.421-22T>G)
c.499-22T>G (n.499-22T>G)
c.610-22T>G (n.610-22T>G)
c.502T>G (p.Phe168Val)
19g.1106379T>ACA402939449GPX4c.613-21T>A (n.613-21T>A)
c.482-21T>A (n.482-21T>A)
c.496-21T>A (n.496-21T>A)
c.118-21T>A (n.118-21T>A)
c.502-21T>A (n.502-21T>A)
c.477-21T>A (n.477-21T>A)
c.235-21T>A (n.235-21T>A)
c.382-21T>A (n.382-21T>A)
c.422T>A (p.Phe141Tyr)
n.873-21T>A
c.421-21T>A (n.421-21T>A)
c.499-21T>A (n.499-21T>A)
c.610-21T>A (n.610-21T>A)
c.503T>A (p.Phe168Tyr)
19g.1106379T>CCA402939452GPX4c.613-21T>C (n.613-21T>C)
c.482-21T>C (n.482-21T>C)
c.496-21T>C (n.496-21T>C)
c.118-21T>C (n.118-21T>C)
c.502-21T>C (n.502-21T>C)
c.477-21T>C (n.477-21T>C)
c.235-21T>C (n.235-21T>C)
c.382-21T>C (n.382-21T>C)
c.422T>C (p.Phe141Ser)
n.873-21T>C
c.421-21T>C (n.421-21T>C)
c.499-21T>C (n.499-21T>C)
c.610-21T>C (n.610-21T>C)
c.503T>C (p.Phe168Ser)
19g.1106379T>GCA402939456GPX4c.613-21T>G (n.613-21T>G)
c.482-21T>G (n.482-21T>G)
c.496-21T>G (n.496-21T>G)
c.118-21T>G (n.118-21T>G)
c.502-21T>G (n.502-21T>G)
c.477-21T>G (n.477-21T>G)
c.235-21T>G (n.235-21T>G)
c.382-21T>G (n.382-21T>G)
c.422T>G (p.Phe141Cys)
n.873-21T>G
c.421-21T>G (n.421-21T>G)
c.499-21T>G (n.499-21T>G)
c.610-21T>G (n.610-21T>G)
c.503T>G (p.Phe168Cys)
19g.1106380T>ACA402939460GPX4c.613-20T>A (n.613-20T>A)
c.482-20T>A (n.482-20T>A)
c.496-20T>A (n.496-20T>A)
c.118-20T>A (n.118-20T>A)
c.502-20T>A (n.502-20T>A)
c.477-20T>A (n.477-20T>A)
c.235-20T>A (n.235-20T>A)
c.382-20T>A (n.382-20T>A)
c.423T>A (p.Phe141Leu)
n.873-20T>A
c.421-20T>A (n.421-20T>A)
c.499-20T>A (n.499-20T>A)
c.610-20T>A (n.610-20T>A)
c.504T>A (p.Phe168Leu)
19g.1106380T>CCA2588207841GPX4c.613-20T>C (n.613-20T>C)
c.482-20T>C (n.482-20T>C)
c.496-20T>C (n.496-20T>C)
c.118-20T>C (n.118-20T>C)
c.502-20T>C (n.502-20T>C)
c.477-20T>C (n.477-20T>C)
c.235-20T>C (n.235-20T>C)
c.382-20T>C (n.382-20T>C)
c.423T>C (p.Phe141=)
n.873-20T>C
c.421-20T>C (n.421-20T>C)
c.499-20T>C (n.499-20T>C)
c.610-20T>C (n.610-20T>C)
c.504T>C (p.Phe168=)
 gnomAD v4
19g.1106380T>GCA402939459GPX4c.613-20T>G (n.613-20T>G)
c.482-20T>G (n.482-20T>G)
c.496-20T>G (n.496-20T>G)
c.118-20T>G (n.118-20T>G)
c.502-20T>G (n.502-20T>G)
c.477-20T>G (n.477-20T>G)
c.235-20T>G (n.235-20T>G)
c.382-20T>G (n.382-20T>G)
c.423T>G (p.Phe141Leu)
n.873-20T>G
c.421-20T>G (n.421-20T>G)
c.499-20T>G (n.499-20T>G)
c.610-20T>G (n.610-20T>G)
c.504T>G (p.Phe168Leu)
 dbSNP
19g.1106380T=CA2317520623GPX4c.613-20T= (n.613-20T=)
c.482-20T= (n.482-20T=)
c.496-20T= (n.496-20T=)
c.118-20T= (n.118-20T=)
c.502-20T= (n.502-20T=)
c.477-20T= (n.477-20T=)
c.235-20T= (n.235-20T=)
c.382-20T= (n.382-20T=)
c.423T= (p.Phe141=)
n.873-20T=
c.421-20T= (n.421-20T=)
c.499-20T= (n.499-20T=)
c.610-20T= (n.610-20T=)
c.504T= (p.Phe168=)
19g.1106381G>ACA9037454GPX4c.613-19G>A (n.613-19G>A)
c.482-19G>A (n.482-19G>A)
c.496-19G>A (n.496-19G>A)
c.118-19G>A (n.118-19G>A)
c.502-19G>A (n.502-19G>A)
c.477-19G>A (n.477-19G>A)
c.235-19G>A (n.235-19G>A)
c.382-19G>A (n.382-19G>A)
c.424G>A (p.Gly142Arg)
n.873-19G>A
c.421-19G>A (n.421-19G>A)
c.499-19G>A (n.499-19G>A)
c.610-19G>A (n.610-19G>A)
c.505G>A (p.Gly169Arg)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106381G>CCA402939463GPX4c.613-19G>C (n.613-19G>C)
c.482-19G>C (n.482-19G>C)
c.496-19G>C (n.496-19G>C)
c.118-19G>C (n.118-19G>C)
c.502-19G>C (n.502-19G>C)
c.477-19G>C (n.477-19G>C)
c.235-19G>C (n.235-19G>C)
c.382-19G>C (n.382-19G>C)
c.424G>C (p.Gly142Arg)
n.873-19G>C
c.421-19G>C (n.421-19G>C)
c.499-19G>C (n.499-19G>C)
c.610-19G>C (n.610-19G>C)
c.505G>C (p.Gly169Arg)
 dbSNP gnomAD v3 gnomAD v4
19g.1106381G=CA2317520624GPX4c.613-19G= (n.613-19G=)
c.482-19G= (n.482-19G=)
c.496-19G= (n.496-19G=)
c.118-19G= (n.118-19G=)
c.502-19G= (n.502-19G=)
c.477-19G= (n.477-19G=)
c.235-19G= (n.235-19G=)
c.382-19G= (n.382-19G=)
c.424G= (p.Gly142=)
n.873-19G=
c.421-19G= (n.421-19G=)
c.499-19G= (n.499-19G=)
c.610-19G= (n.610-19G=)
c.505G= (p.Gly169=)
19g.1106381G>TCA402939466GPX4c.613-19G>T (n.613-19G>T)
c.482-19G>T (n.482-19G>T)
c.496-19G>T (n.496-19G>T)
c.118-19G>T (n.118-19G>T)
c.502-19G>T (n.502-19G>T)
c.477-19G>T (n.477-19G>T)
c.235-19G>T (n.235-19G>T)
c.382-19G>T (n.382-19G>T)
c.424G>T (p.Gly142Ter)
n.873-19G>T
c.421-19G>T (n.421-19G>T)
c.499-19G>T (n.499-19G>T)
c.610-19G>T (n.610-19G>T)
c.505G>T (p.Gly169Ter)
19g.1106382G>ACA402939470GPX4c.613-18G>A (n.613-18G>A)
c.482-18G>A (n.482-18G>A)
c.496-18G>A (n.496-18G>A)
c.118-18G>A (n.118-18G>A)
c.502-18G>A (n.502-18G>A)
c.477-18G>A (n.477-18G>A)
c.235-18G>A (n.235-18G>A)
c.382-18G>A (n.382-18G>A)
c.425G>A (p.Gly142Glu)
n.873-18G>A
c.421-18G>A (n.421-18G>A)
c.499-18G>A (n.499-18G>A)
c.610-18G>A (n.610-18G>A)
c.506G>A (p.Gly169Glu)
19g.1106382G>CCA402939473GPX4c.613-18G>C (n.613-18G>C)
c.482-18G>C (n.482-18G>C)
c.496-18G>C (n.496-18G>C)
c.118-18G>C (n.118-18G>C)
c.502-18G>C (n.502-18G>C)
c.477-18G>C (n.477-18G>C)
c.235-18G>C (n.235-18G>C)
c.382-18G>C (n.382-18G>C)
c.425G>C (p.Gly142Ala)
n.873-18G>C
c.421-18G>C (n.421-18G>C)
c.499-18G>C (n.499-18G>C)
c.610-18G>C (n.610-18G>C)
c.506G>C (p.Gly169Ala)
19g.1106382G=CA2317520625GPX4c.613-18G= (n.613-18G=)
c.482-18G= (n.482-18G=)
c.496-18G= (n.496-18G=)
c.118-18G= (n.118-18G=)
c.502-18G= (n.502-18G=)
c.477-18G= (n.477-18G=)
c.235-18G= (n.235-18G=)
c.382-18G= (n.382-18G=)
c.425G= (p.Gly142=)
n.873-18G=
c.421-18G= (n.421-18G=)
c.499-18G= (n.499-18G=)
c.610-18G= (n.610-18G=)
c.506G= (p.Gly169=)
19g.1106382G>TCA402939481GPX4c.613-18G>T (n.613-18G>T)
c.482-18G>T (n.482-18G>T)
c.496-18G>T (n.496-18G>T)
c.118-18G>T (n.118-18G>T)
c.502-18G>T (n.502-18G>T)
c.477-18G>T (n.477-18G>T)
c.235-18G>T (n.235-18G>T)
c.382-18G>T (n.382-18G>T)
c.425G>T (p.Gly142Val)
n.873-18G>T
c.421-18G>T (n.421-18G>T)
c.499-18G>T (n.499-18G>T)
c.610-18G>T (n.610-18G>T)
c.506G>T (p.Gly169Val)
 dbSNP gnomAD v4
19g.1106383A>TCA2588207842GPX4c.613-17A>T (n.613-17A>T)
c.482-17A>T (n.482-17A>T)
c.496-17A>T (n.496-17A>T)
c.118-17A>T (n.118-17A>T)
c.502-17A>T (n.502-17A>T)
c.477-17A>T (n.477-17A>T)
c.235-17A>T (n.235-17A>T)
c.382-17A>T (n.382-17A>T)
c.426A>T (p.Gly142=)
n.873-17A>T
c.421-17A>T (n.421-17A>T)
c.499-17A>T (n.499-17A>T)
c.610-17A>T (n.610-17A>T)
c.507A>T (p.Gly169=)
 gnomAD v4
19g.1106384C>ACA402939485GPX4c.613-16C>A (n.613-16C>A)
c.482-16C>A (n.482-16C>A)
c.496-16C>A (n.496-16C>A)
c.118-16C>A (n.118-16C>A)
c.502-16C>A (n.502-16C>A)
c.477-16C>A (n.477-16C>A)
c.235-16C>A (n.235-16C>A)
c.382-16C>A (n.382-16C>A)
c.427C>A (p.His143Asn)
n.873-16C>A
c.421-16C>A (n.421-16C>A)
c.499-16C>A (n.499-16C>A)
c.610-16C>A (n.610-16C>A)
c.508C>A (p.His170Asn)
19g.1106384C=CA2317520626GPX4c.613-16C= (n.613-16C=)
c.482-16C= (n.482-16C=)
c.496-16C= (n.496-16C=)
c.118-16C= (n.118-16C=)
c.502-16C= (n.502-16C=)
c.477-16C= (n.477-16C=)
c.235-16C= (n.235-16C=)
c.382-16C= (n.382-16C=)
c.427C= (p.His143=)
n.873-16C=
c.421-16C= (n.421-16C=)
c.499-16C= (n.499-16C=)
c.610-16C= (n.610-16C=)
c.508C= (p.His170=)
19g.1106384C>GCA402939513GPX4c.613-16C>G (n.613-16C>G)
c.482-16C>G (n.482-16C>G)
c.496-16C>G (n.496-16C>G)
c.118-16C>G (n.118-16C>G)
c.502-16C>G (n.502-16C>G)
c.477-16C>G (n.477-16C>G)
c.235-16C>G (n.235-16C>G)
c.382-16C>G (n.382-16C>G)
c.427C>G (p.His143Asp)
n.873-16C>G
c.421-16C>G (n.421-16C>G)
c.499-16C>G (n.499-16C>G)
c.610-16C>G (n.610-16C>G)
c.508C>G (p.His170Asp)
19g.1106384C>TCA303994769GPX4c.613-16C>T (n.613-16C>T)
c.482-16C>T (n.482-16C>T)
c.496-16C>T (n.496-16C>T)
c.118-16C>T (n.118-16C>T)
c.502-16C>T (n.502-16C>T)
c.477-16C>T (n.477-16C>T)
c.235-16C>T (n.235-16C>T)
c.382-16C>T (n.382-16C>T)
c.427C>T (p.His143Tyr)
n.873-16C>T
c.421-16C>T (n.421-16C>T)
c.499-16C>T (n.499-16C>T)
c.610-16C>T (n.610-16C>T)
c.508C>T (p.His170Tyr)
 dbSNP gnomAD v4
19g.1106385A>CCA402939516GPX4c.613-15A>C (n.613-15A>C)
c.482-15A>C (n.482-15A>C)
c.496-15A>C (n.496-15A>C)
c.118-15A>C (n.118-15A>C)
c.502-15A>C (n.502-15A>C)
c.477-15A>C (n.477-15A>C)
c.235-15A>C (n.235-15A>C)
c.382-15A>C (n.382-15A>C)
c.428A>C (p.His143Pro)
n.873-15A>C
c.421-15A>C (n.421-15A>C)
c.499-15A>C (n.499-15A>C)
c.610-15A>C (n.610-15A>C)
c.509A>C (p.His170Pro)
19g.1106385A>GCA402939517GPX4c.613-15A>G (n.613-15A>G)
c.482-15A>G (n.482-15A>G)
c.496-15A>G (n.496-15A>G)
c.118-15A>G (n.118-15A>G)
c.502-15A>G (n.502-15A>G)
c.477-15A>G (n.477-15A>G)
c.235-15A>G (n.235-15A>G)
c.382-15A>G (n.382-15A>G)
c.428A>G (p.His143Arg)
n.873-15A>G
c.421-15A>G (n.421-15A>G)
c.499-15A>G (n.499-15A>G)
c.610-15A>G (n.610-15A>G)
c.509A>G (p.His170Arg)
19g.1106385A>TCA402939519GPX4c.613-15A>T (n.613-15A>T)
c.482-15A>T (n.482-15A>T)
c.496-15A>T (n.496-15A>T)
c.118-15A>T (n.118-15A>T)
c.502-15A>T (n.502-15A>T)
c.477-15A>T (n.477-15A>T)
c.235-15A>T (n.235-15A>T)
c.382-15A>T (n.382-15A>T)
c.428A>T (p.His143Leu)
n.873-15A>T
c.421-15A>T (n.421-15A>T)
c.499-15A>T (n.499-15A>T)
c.610-15A>T (n.610-15A>T)
c.509A>T (p.His170Leu)
19g.1106386C>ACA9037455GPX4c.613-14C>A (n.613-14C>A)
c.482-14C>A (n.482-14C>A)
c.496-14C>A (n.496-14C>A)
c.118-14C>A (n.118-14C>A)
c.502-14C>A (n.502-14C>A)
c.477-14C>A (n.477-14C>A)
c.235-14C>A (n.235-14C>A)
c.382-14C>A (n.382-14C>A)
c.429C>A (p.His143Gln)
n.873-14C>A
c.421-14C>A (n.421-14C>A)
c.499-14C>A (n.499-14C>A)
c.610-14C>A (n.610-14C>A)
c.510C>A (p.His170Gln)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106386C=CA2317520627GPX4c.613-14C= (n.613-14C=)
c.482-14C= (n.482-14C=)
c.496-14C= (n.496-14C=)
c.118-14C= (n.118-14C=)
c.502-14C= (n.502-14C=)
c.477-14C= (n.477-14C=)
c.235-14C= (n.235-14C=)
c.382-14C= (n.382-14C=)
c.429C= (p.His143=)
n.873-14C=
c.421-14C= (n.421-14C=)
c.499-14C= (n.499-14C=)
c.610-14C= (n.610-14C=)
c.510C= (p.His170=)
19g.1106386C>GCA402939523GPX4c.613-14C>G (n.613-14C>G)
c.482-14C>G (n.482-14C>G)
c.496-14C>G (n.496-14C>G)
c.118-14C>G (n.118-14C>G)
c.502-14C>G (n.502-14C>G)
c.477-14C>G (n.477-14C>G)
c.235-14C>G (n.235-14C>G)
c.382-14C>G (n.382-14C>G)
c.429C>G (p.His143Gln)
n.873-14C>G
c.421-14C>G (n.421-14C>G)
c.499-14C>G (n.499-14C>G)
c.610-14C>G (n.610-14C>G)
c.510C>G (p.His170Gln)
 gnomAD v4
19g.1106386C>TCA631298714GPX4c.613-14C>T (n.613-14C>T)
c.482-14C>T (n.482-14C>T)
c.496-14C>T (n.496-14C>T)
c.118-14C>T (n.118-14C>T)
c.502-14C>T (n.502-14C>T)
c.477-14C>T (n.477-14C>T)
c.235-14C>T (n.235-14C>T)
c.382-14C>T (n.382-14C>T)
c.429C>T (p.His143=)
n.873-14C>T
c.421-14C>T (n.421-14C>T)
c.499-14C>T (n.499-14C>T)
c.610-14C>T (n.610-14C>T)
c.510C>T (p.His170=)
 dbSNP gnomAD v2 gnomAD v4
19g.1106387C>ACA9037456GPX4c.613-13C>A (n.613-13C>A)
c.482-13C>A (n.482-13C>A)
c.496-13C>A (n.496-13C>A)
c.118-13C>A (n.118-13C>A)
c.502-13C>A (n.502-13C>A)
c.477-13C>A (n.477-13C>A)
c.235-13C>A (n.235-13C>A)
c.382-13C>A (n.382-13C>A)
c.430C>A (p.Arg144Ser)
n.873-13C>A
c.421-13C>A (n.421-13C>A)
c.499-13C>A (n.499-13C>A)
c.610-13C>A (n.610-13C>A)
c.511C>A (p.Arg171Ser)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106387C=CA2317520628GPX4c.613-13C= (n.613-13C=)
c.482-13C= (n.482-13C=)
c.496-13C= (n.496-13C=)
c.118-13C= (n.118-13C=)
c.502-13C= (n.502-13C=)
c.477-13C= (n.477-13C=)
c.235-13C= (n.235-13C=)
c.382-13C= (n.382-13C=)
c.430C= (p.Arg144=)
n.873-13C=
c.421-13C= (n.421-13C=)
c.499-13C= (n.499-13C=)
c.610-13C= (n.610-13C=)
c.511C= (p.Arg171=)
19g.1106387C>GCA402939529GPX4c.613-13C>G (n.613-13C>G)
c.482-13C>G (n.482-13C>G)
c.496-13C>G (n.496-13C>G)
c.118-13C>G (n.118-13C>G)
c.502-13C>G (n.502-13C>G)
c.477-13C>G (n.477-13C>G)
c.235-13C>G (n.235-13C>G)
c.382-13C>G (n.382-13C>G)
c.430C>G (p.Arg144Gly)
n.873-13C>G
c.421-13C>G (n.421-13C>G)
c.499-13C>G (n.499-13C>G)
c.610-13C>G (n.610-13C>G)
c.511C>G (p.Arg171Gly)
 dbSNP gnomAD v4
19g.1106387C>TCA402939533GPX4c.613-13C>T (n.613-13C>T)
c.482-13C>T (n.482-13C>T)
c.496-13C>T (n.496-13C>T)
c.118-13C>T (n.118-13C>T)
c.502-13C>T (n.502-13C>T)
c.477-13C>T (n.477-13C>T)
c.235-13C>T (n.235-13C>T)
c.382-13C>T (n.382-13C>T)
c.430C>T (p.Arg144Cys)
n.873-13C>T
c.421-13C>T (n.421-13C>T)
c.499-13C>T (n.499-13C>T)
c.610-13C>T (n.610-13C>T)
c.511C>T (p.Arg171Cys)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
19g.1106388G>ACA9037457GPX4c.613-12G>A (n.613-12G>A)
c.482-12G>A (n.482-12G>A)
c.496-12G>A (n.496-12G>A)
c.118-12G>A (n.118-12G>A)
c.502-12G>A (n.502-12G>A)
c.477-12G>A (n.477-12G>A)
c.235-12G>A (n.235-12G>A)
c.382-12G>A (n.382-12G>A)
c.431G>A (p.Arg144His)
n.873-12G>A
c.421-12G>A (n.421-12G>A)
c.499-12G>A (n.499-12G>A)
c.610-12G>A (n.610-12G>A)
c.512G>A (p.Arg171His)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106388G>CCA402939543GPX4c.613-12G>C (n.613-12G>C)
c.482-12G>C (n.482-12G>C)
c.496-12G>C (n.496-12G>C)
c.118-12G>C (n.118-12G>C)
c.502-12G>C (n.502-12G>C)
c.477-12G>C (n.477-12G>C)
c.235-12G>C (n.235-12G>C)
c.382-12G>C (n.382-12G>C)
c.431G>C (p.Arg144Pro)
n.873-12G>C
c.421-12G>C (n.421-12G>C)
c.499-12G>C (n.499-12G>C)
c.610-12G>C (n.610-12G>C)
c.512G>C (p.Arg171Pro)
 dbSNP gnomAD v3 gnomAD v4
19g.1106388G=CA2317520629GPX4c.613-12G= (n.613-12G=)
c.482-12G= (n.482-12G=)
c.496-12G= (n.496-12G=)
c.118-12G= (n.118-12G=)
c.502-12G= (n.502-12G=)
c.477-12G= (n.477-12G=)
c.235-12G= (n.235-12G=)
c.382-12G= (n.382-12G=)
c.431G= (p.Arg144=)
n.873-12G=
c.421-12G= (n.421-12G=)
c.499-12G= (n.499-12G=)
c.610-12G= (n.610-12G=)
c.512G= (p.Arg171=)
19g.1106388G>TCA9037458GPX4c.613-12G>T (n.613-12G>T)
c.482-12G>T (n.482-12G>T)
c.496-12G>T (n.496-12G>T)
c.118-12G>T (n.118-12G>T)
c.502-12G>T (n.502-12G>T)
c.477-12G>T (n.477-12G>T)
c.235-12G>T (n.235-12G>T)
c.382-12G>T (n.382-12G>T)
c.431G>T (p.Arg144Leu)
n.873-12G>T
c.421-12G>T (n.421-12G>T)
c.499-12G>T (n.499-12G>T)
c.610-12G>T (n.610-12G>T)
c.512G>T (p.Arg171Leu)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106389T>CCA9037459GPX4c.613-11T>C (n.613-11T>C)
c.482-11T>C (n.482-11T>C)
c.496-11T>C (n.496-11T>C)
c.118-11T>C (n.118-11T>C)
c.502-11T>C (n.502-11T>C)
c.477-11T>C (n.477-11T>C)
c.235-11T>C (n.235-11T>C)
c.382-11T>C (n.382-11T>C)
c.432T>C (p.Arg144=)
n.873-11T>C
c.421-11T>C (n.421-11T>C)
c.499-11T>C (n.499-11T>C)
c.610-11T>C (n.610-11T>C)
c.513T>C (p.Arg171=)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106389T=CA2317520630GPX4c.613-11T= (n.613-11T=)
c.482-11T= (n.482-11T=)
c.496-11T= (n.496-11T=)
c.118-11T= (n.118-11T=)
c.502-11T= (n.502-11T=)
c.477-11T= (n.477-11T=)
c.235-11T= (n.235-11T=)
c.382-11T= (n.382-11T=)
c.432T= (p.Arg144=)
n.873-11T=
c.421-11T= (n.421-11T=)
c.499-11T= (n.499-11T=)
c.610-11T= (n.610-11T=)
c.513T= (p.Arg171=)
19g.1106389_1106401dupCA2588207843GPX4c.613-11_614dup
c.482-11_483dup
c.496-11_497dup
c.118-11_119dup
c.502-11_503dup
c.477-11_478dup
c.235-11_236dup
c.382-11_383dup
c.432_444dup (p.Pro149SerfsTer14)
n.873-11_874dup
c.421-11_422dup
c.499-11_500dup
c.610-11_611dup
c.513_525dup (p.Pro176SerfsTer14)
 gnomAD v4
19g.1106390C>ACA402939557GPX4c.613-10C>A (n.613-10C>A)
c.482-10C>A (n.482-10C>A)
c.496-10C>A (n.496-10C>A)
c.118-10C>A (n.118-10C>A)
c.502-10C>A (n.502-10C>A)
c.477-10C>A (n.477-10C>A)
c.235-10C>A (n.235-10C>A)
c.382-10C>A (n.382-10C>A)
c.433C>A (p.Leu145Ile)
n.873-10C>A
c.421-10C>A (n.421-10C>A)
c.499-10C>A (n.499-10C>A)
c.610-10C>A (n.610-10C>A)
c.514C>A (p.Leu172Ile)
19g.1106390C>GCA402939555GPX4c.613-10C>G (n.613-10C>G)
c.482-10C>G (n.482-10C>G)
c.496-10C>G (n.496-10C>G)
c.118-10C>G (n.118-10C>G)
c.502-10C>G (n.502-10C>G)
c.477-10C>G (n.477-10C>G)
c.235-10C>G (n.235-10C>G)
c.382-10C>G (n.382-10C>G)
c.433C>G (p.Leu145Val)
n.873-10C>G
c.421-10C>G (n.421-10C>G)
c.499-10C>G (n.499-10C>G)
c.610-10C>G (n.610-10C>G)
c.514C>G (p.Leu172Val)
19g.1106390C>TCA402939559GPX4c.613-10C>T (n.613-10C>T)
c.482-10C>T (n.482-10C>T)
c.496-10C>T (n.496-10C>T)
c.118-10C>T (n.118-10C>T)
c.502-10C>T (n.502-10C>T)
c.477-10C>T (n.477-10C>T)
c.235-10C>T (n.235-10C>T)
c.382-10C>T (n.382-10C>T)
c.433C>T (p.Leu145Phe)
n.873-10C>T
c.421-10C>T (n.421-10C>T)
c.499-10C>T (n.499-10C>T)
c.610-10C>T (n.610-10C>T)
c.514C>T (p.Leu172Phe)
 gnomAD v4
19g.1106391T>ACA402939560GPX4c.613-9T>A (n.613-9T>A)
c.482-9T>A (n.482-9T>A)
c.496-9T>A (n.496-9T>A)
c.118-9T>A (n.118-9T>A)
c.502-9T>A (n.502-9T>A)
c.477-9T>A (n.477-9T>A)
c.235-9T>A (n.235-9T>A)
c.382-9T>A (n.382-9T>A)
c.434T>A (p.Leu145His)
n.873-9T>A
c.421-9T>A (n.421-9T>A)
c.499-9T>A (n.499-9T>A)
c.610-9T>A (n.610-9T>A)
c.515T>A (p.Leu172His)
19g.1106391T>CCA402939563GPX4c.613-9T>C (n.613-9T>C)
c.482-9T>C (n.482-9T>C)
c.496-9T>C (n.496-9T>C)
c.118-9T>C (n.118-9T>C)
c.502-9T>C (n.502-9T>C)
c.477-9T>C (n.477-9T>C)
c.235-9T>C (n.235-9T>C)
c.382-9T>C (n.382-9T>C)
c.434T>C (p.Leu145Pro)
n.873-9T>C
c.421-9T>C (n.421-9T>C)
c.499-9T>C (n.499-9T>C)
c.610-9T>C (n.610-9T>C)
c.515T>C (p.Leu172Pro)
19g.1106391T>GCA402939562GPX4c.613-9T>G (n.613-9T>G)
c.482-9T>G (n.482-9T>G)
c.496-9T>G (n.496-9T>G)
c.118-9T>G (n.118-9T>G)
c.502-9T>G (n.502-9T>G)
c.477-9T>G (n.477-9T>G)
c.235-9T>G (n.235-9T>G)
c.382-9T>G (n.382-9T>G)
c.434T>G (p.Leu145Arg)
n.873-9T>G
c.421-9T>G (n.421-9T>G)
c.499-9T>G (n.499-9T>G)
c.610-9T>G (n.610-9T>G)
c.515T>G (p.Leu172Arg)
19g.1106392C>ACA2588207846GPX4c.613-8C>A (n.613-8C>A)
c.482-8C>A (n.482-8C>A)
c.496-8C>A (n.496-8C>A)
c.118-8C>A (n.118-8C>A)
c.502-8C>A (n.502-8C>A)
c.477-8C>A (n.477-8C>A)
c.235-8C>A (n.235-8C>A)
c.382-8C>A (n.382-8C>A)
c.435C>A (p.Leu145=)
n.873-8C>A
c.421-8C>A (n.421-8C>A)
c.499-8C>A (n.499-8C>A)
c.610-8C>A (n.610-8C>A)
c.516C>A (p.Leu172=)
 gnomAD v4
19g.1106392C>GCA2588207845GPX4c.613-8C>G (n.613-8C>G)
c.482-8C>G (n.482-8C>G)
c.496-8C>G (n.496-8C>G)
c.118-8C>G (n.118-8C>G)
c.502-8C>G (n.502-8C>G)
c.477-8C>G (n.477-8C>G)
c.235-8C>G (n.235-8C>G)
c.382-8C>G (n.382-8C>G)
c.435C>G (p.Leu145=)
n.873-8C>G
c.421-8C>G (n.421-8C>G)
c.499-8C>G (n.499-8C>G)
c.610-8C>G (n.610-8C>G)
c.516C>G (p.Leu172=)
 gnomAD v4
19g.1106392C>TCA2588207844GPX4c.613-8C>T (n.613-8C>T)
c.482-8C>T (n.482-8C>T)
c.496-8C>T (n.496-8C>T)
c.118-8C>T (n.118-8C>T)
c.502-8C>T (n.502-8C>T)
c.477-8C>T (n.477-8C>T)
c.235-8C>T (n.235-8C>T)
c.382-8C>T (n.382-8C>T)
c.435C>T (p.Leu145=)
n.873-8C>T
c.421-8C>T (n.421-8C>T)
c.499-8C>T (n.499-8C>T)
c.610-8C>T (n.610-8C>T)
c.516C>T (p.Leu172=)
 gnomAD v4
19g.1106393T>ACA402939565GPX4c.613-7T>A (n.613-7T>A)
c.482-7T>A (n.482-7T>A)
c.496-7T>A (n.496-7T>A)
c.118-7T>A (n.118-7T>A)
c.502-7T>A (n.502-7T>A)
c.477-7T>A (n.477-7T>A)
c.235-7T>A (n.235-7T>A)
c.382-7T>A (n.382-7T>A)
c.436T>A (p.Ser146Thr)
n.873-7T>A
c.421-7T>A (n.421-7T>A)
c.499-7T>A (n.499-7T>A)
c.610-7T>A (n.610-7T>A)
c.517T>A (p.Ser173Thr)
19g.1106393T>CCA402939568GPX4c.613-7T>C (n.613-7T>C)
c.482-7T>C (n.482-7T>C)
c.496-7T>C (n.496-7T>C)
c.118-7T>C (n.118-7T>C)
c.502-7T>C (n.502-7T>C)
c.477-7T>C (n.477-7T>C)
c.235-7T>C (n.235-7T>C)
c.382-7T>C (n.382-7T>C)
c.436T>C (p.Ser146Pro)
n.873-7T>C
c.421-7T>C (n.421-7T>C)
c.499-7T>C (n.499-7T>C)
c.610-7T>C (n.610-7T>C)
c.517T>C (p.Ser173Pro)
19g.1106393T>GCA402939566GPX4c.613-7T>G (n.613-7T>G)
c.482-7T>G (n.482-7T>G)
c.496-7T>G (n.496-7T>G)
c.118-7T>G (n.118-7T>G)
c.502-7T>G (n.502-7T>G)
c.477-7T>G (n.477-7T>G)
c.235-7T>G (n.235-7T>G)
c.382-7T>G (n.382-7T>G)
c.436T>G (p.Ser146Ala)
n.873-7T>G
c.421-7T>G (n.421-7T>G)
c.499-7T>G (n.499-7T>G)
c.610-7T>G (n.610-7T>G)
c.517T>G (p.Ser173Ala)
19g.1106394C>ACA402939570GPX4c.613-6C>A (n.613-6C>A)
c.482-6C>A (n.482-6C>A)
c.496-6C>A (n.496-6C>A)
c.118-6C>A (n.118-6C>A)
c.502-6C>A (n.502-6C>A)
c.477-6C>A (n.477-6C>A)
c.235-6C>A (n.235-6C>A)
c.382-6C>A (n.382-6C>A)
c.437C>A (p.Ser146Tyr)
n.873-6C>A
c.421-6C>A (n.421-6C>A)
c.499-6C>A (n.499-6C>A)
c.610-6C>A (n.610-6C>A)
c.518C>A (p.Ser173Tyr)
19g.1106394C=CA2317520631GPX4c.613-6C= (n.613-6C=)
c.482-6C= (n.482-6C=)
c.496-6C= (n.496-6C=)
c.118-6C= (n.118-6C=)
c.502-6C= (n.502-6C=)
c.477-6C= (n.477-6C=)
c.235-6C= (n.235-6C=)
c.382-6C= (n.382-6C=)
c.437C= (p.Ser146=)
n.873-6C=
c.421-6C= (n.421-6C=)
c.499-6C= (n.499-6C=)
c.610-6C= (n.610-6C=)
c.518C= (p.Ser173=)
19g.1106394C>GCA9037460GPX4c.613-6C>G (n.613-6C>G)
c.482-6C>G (n.482-6C>G)
c.496-6C>G (n.496-6C>G)
c.118-6C>G (n.118-6C>G)
c.502-6C>G (n.502-6C>G)
c.477-6C>G (n.477-6C>G)
c.235-6C>G (n.235-6C>G)
c.382-6C>G (n.382-6C>G)
c.437C>G (p.Ser146Cys)
n.873-6C>G
c.421-6C>G (n.421-6C>G)
c.499-6C>G (n.499-6C>G)
c.610-6C>G (n.610-6C>G)
c.518C>G (p.Ser173Cys)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106394C>TCA402939574GPX4c.613-6C>T (n.613-6C>T)
c.482-6C>T (n.482-6C>T)
c.496-6C>T (n.496-6C>T)
c.118-6C>T (n.118-6C>T)
c.502-6C>T (n.502-6C>T)
c.477-6C>T (n.477-6C>T)
c.235-6C>T (n.235-6C>T)
c.382-6C>T (n.382-6C>T)
c.437C>T (p.Ser146Phe)
n.873-6C>T
c.421-6C>T (n.421-6C>T)
c.499-6C>T (n.499-6C>T)
c.610-6C>T (n.610-6C>T)
c.518C>T (p.Ser173Phe)
19g.1106394_1106396delinsCCACA2317520632GPX4c.613-6_613-4delinsCCA (n.613-6_613-4delinsCCA)
c.482-6_482-4delinsCCA (n.482-6_482-4delinsCCA)
c.496-6_496-4delinsCCA (n.496-6_496-4delinsCCA)
c.118-6_118-4delinsCCA (n.118-6_118-4delinsCCA)
c.502-6_502-4delinsCCA (n.502-6_502-4delinsCCA)
c.477-6_477-4delinsCCA (n.477-6_477-4delinsCCA)
c.235-6_235-4delinsCCA (n.235-6_235-4delinsCCA)
c.382-6_382-4delinsCCA (n.382-6_382-4delinsCCA)
c.437_439delinsCCA (p.Ser146=)
n.873-6_873-4delinsCCA
c.421-6_421-4delinsCCA (n.421-6_421-4delinsCCA)
c.499-6_499-4delinsCCA (n.499-6_499-4delinsCCA)
c.610-6_610-4delinsCCA (n.610-6_610-4delinsCCA)
c.518_520delinsCCA (p.Ser173=)
19g.1106395C=CA2317520633GPX4c.613-5C= (n.613-5C=)
c.482-5C= (n.482-5C=)
c.496-5C= (n.496-5C=)
c.118-5C= (n.118-5C=)
c.502-5C= (n.502-5C=)
c.477-5C= (n.477-5C=)
c.235-5C= (n.235-5C=)
c.382-5C= (n.382-5C=)
c.438C= (p.Ser146=)
n.873-5C=
c.421-5C= (n.421-5C=)
c.499-5C= (n.499-5C=)
c.610-5C= (n.610-5C=)
c.519C= (p.Ser173=)
19g.1106395C>TCA2317520634GPX4c.613-5C>T (n.613-5C>T)
c.482-5C>T (n.482-5C>T)
c.496-5C>T (n.496-5C>T)
c.118-5C>T (n.118-5C>T)
c.502-5C>T (n.502-5C>T)
c.477-5C>T (n.477-5C>T)
c.235-5C>T (n.235-5C>T)
c.382-5C>T (n.382-5C>T)
c.438C>T (p.Ser146=)
n.873-5C>T
c.421-5C>T (n.421-5C>T)
c.499-5C>T (n.499-5C>T)
c.610-5C>T (n.610-5C>T)
c.519C>T (p.Ser173=)
 dbSNP gnomAD v4
19g.1106397_1106398delCA631298717GPX4c.613-3_613-2del (n.613-3_613-2del)
c.482-3_482-2del (n.482-3_482-2del)
c.496-3_496-2del (n.496-3_496-2del)
c.118-3_118-2del (n.118-3_118-2del)
c.502-3_502-2del (n.502-3_502-2del)
c.477-3_477-2del (n.477-3_477-2del)
c.235-3_235-2del (n.235-3_235-2del)
c.382-3_382-2del (n.382-3_382-2del)
c.440_441del (p.Thr147SerfsTer11)
n.873-3_873-2del
c.421-3_421-2del (n.421-3_421-2del)
c.499-3_499-2del (n.499-3_499-2del)
c.610-3_610-2del (n.610-3_610-2del)
c.521_522del (p.Thr174SerfsTer11)
 dbSNP gnomAD v2 gnomAD v4
19g.1106396A=CA2317520636GPX4c.613-4A= (n.613-4A=)
c.482-4A= (n.482-4A=)
c.496-4A= (n.496-4A=)
c.118-4A= (n.118-4A=)
c.502-4A= (n.502-4A=)
c.477-4A= (n.477-4A=)
c.235-4A= (n.235-4A=)
c.382-4A= (n.382-4A=)
c.439A= (p.Thr147=)
n.873-4A=
c.421-4A= (n.421-4A=)
c.499-4A= (n.499-4A=)
c.610-4A= (n.610-4A=)
c.520A= (p.Thr174=)
19g.1106396A>CCA402939577GPX4c.613-4A>C (n.613-4A>C)
c.482-4A>C (n.482-4A>C)
c.496-4A>C (n.496-4A>C)
c.118-4A>C (n.118-4A>C)
c.502-4A>C (n.502-4A>C)
c.477-4A>C (n.477-4A>C)
c.235-4A>C (n.235-4A>C)
c.382-4A>C (n.382-4A>C)
c.439A>C (p.Thr147Pro)
n.873-4A>C
c.421-4A>C (n.421-4A>C)
c.499-4A>C (n.499-4A>C)
c.610-4A>C (n.610-4A>C)
c.520A>C (p.Thr174Pro)
19g.1106396A>GCA402939581GPX4c.613-4A>G (n.613-4A>G)
c.482-4A>G (n.482-4A>G)
c.496-4A>G (n.496-4A>G)
c.118-4A>G (n.118-4A>G)
c.502-4A>G (n.502-4A>G)
c.477-4A>G (n.477-4A>G)
c.235-4A>G (n.235-4A>G)
c.382-4A>G (n.382-4A>G)
c.439A>G (p.Thr147Ala)
n.873-4A>G
c.421-4A>G (n.421-4A>G)
c.499-4A>G (n.499-4A>G)
c.610-4A>G (n.610-4A>G)
c.520A>G (p.Thr174Ala)
 dbSNP gnomAD v2
19g.1106396A>TCA402939583GPX4c.613-4A>T (n.613-4A>T)
c.482-4A>T (n.482-4A>T)
c.496-4A>T (n.496-4A>T)
c.118-4A>T (n.118-4A>T)
c.502-4A>T (n.502-4A>T)
c.477-4A>T (n.477-4A>T)
c.235-4A>T (n.235-4A>T)
c.382-4A>T (n.382-4A>T)
c.439A>T (p.Thr147Ser)
n.873-4A>T
c.421-4A>T (n.421-4A>T)
c.499-4A>T (n.499-4A>T)
c.610-4A>T (n.610-4A>T)
c.520A>T (p.Thr174Ser)
19g.1106396_1106404delinsACAGTTCCTCA2317520635GPX4c.613-4_617delinsACAGTTCCT
c.482-4_486delinsACAGTTCCT
c.496-4_500delinsACAGTTCCT
c.118-4_122delinsACAGTTCCT
c.502-4_506delinsACAGTTCCT
c.477-4_481delinsACAGTTCCT
c.235-4_239delinsACAGTTCCT
c.382-4_386delinsACAGTTCCT
c.439_447delinsACAGTTCCT (p.Thr147=)
n.873-4_877delinsACAGTTCCT
c.421-4_425delinsACAGTTCCT
c.499-4_503delinsACAGTTCCT
c.610-4_614delinsACAGTTCCT
c.520_528delinsACAGTTCCT (p.Thr174=)
19g.1106397C>ACA402939585GPX4c.613-3C>A (n.613-3C>A)
c.482-3C>A (n.482-3C>A)
c.496-3C>A (n.496-3C>A)
c.118-3C>A (n.118-3C>A)
c.502-3C>A (n.502-3C>A)
c.477-3C>A (n.477-3C>A)
c.235-3C>A (n.235-3C>A)
c.382-3C>A (n.382-3C>A)
c.440C>A (p.Thr147Lys)
n.873-3C>A
c.421-3C>A (n.421-3C>A)
c.499-3C>A (n.499-3C>A)
c.610-3C>A (n.610-3C>A)
c.521C>A (p.Thr174Lys)
19g.1106397C>GCA402939589GPX4c.613-3C>G (n.613-3C>G)
c.482-3C>G (n.482-3C>G)
c.496-3C>G (n.496-3C>G)
c.118-3C>G (n.118-3C>G)
c.502-3C>G (n.502-3C>G)
c.477-3C>G (n.477-3C>G)
c.235-3C>G (n.235-3C>G)
c.382-3C>G (n.382-3C>G)
c.440C>G (p.Thr147Arg)
n.873-3C>G
c.421-3C>G (n.421-3C>G)
c.499-3C>G (n.499-3C>G)
c.610-3C>G (n.610-3C>G)
c.521C>G (p.Thr174Arg)
19g.1106397C>TCA402939591GPX4c.613-3C>T (n.613-3C>T)
c.482-3C>T (n.482-3C>T)
c.496-3C>T (n.496-3C>T)
c.118-3C>T (n.118-3C>T)
c.502-3C>T (n.502-3C>T)
c.477-3C>T (n.477-3C>T)
c.235-3C>T (n.235-3C>T)
c.382-3C>T (n.382-3C>T)
c.440C>T (p.Thr147Ile)
n.873-3C>T
c.421-3C>T (n.421-3C>T)
c.499-3C>T (n.499-3C>T)
c.610-3C>T (n.610-3C>T)
c.521C>T (p.Thr174Ile)
 gnomAD v4
19g.1106399_1106406delCA2317520637GPX4c.613-1_619del
c.482-1_488del
c.496-1_502del
c.118-1_124del
c.502-1_508del
c.477-1_483del
c.235-1_241del
c.382-1_388del
c.442_449del (p.Val148SerfsTer8)
n.873-1_879del
c.421-1_427del
c.499-1_505del
c.610-1_616del
c.523_530del (p.Val175SerfsTer8)
 ClinVar dbSNP gnomAD v4
19g.1106398A>CCA402939594GPX4c.613-2A>C (n.613-2A>C)
c.482-2A>C (n.482-2A>C)
c.496-2A>C (n.496-2A>C)
c.118-2A>C (n.118-2A>C)
c.502-2A>C (n.502-2A>C)
c.477-2A>C (n.477-2A>C)
c.235-2A>C (n.235-2A>C)
c.382-2A>C (n.382-2A>C)
c.441A>C (p.Thr147=)
n.873-2A>C
c.421-2A>C (n.421-2A>C)
c.499-2A>C (n.499-2A>C)
c.610-2A>C (n.610-2A>C)
c.522A>C (p.Thr174=)
19g.1106398A>GCA402939598GPX4c.613-2A>G (n.613-2A>G)
c.482-2A>G (n.482-2A>G)
c.496-2A>G (n.496-2A>G)
c.118-2A>G (n.118-2A>G)
c.502-2A>G (n.502-2A>G)
c.477-2A>G (n.477-2A>G)
c.235-2A>G (n.235-2A>G)
c.382-2A>G (n.382-2A>G)
c.441A>G (p.Thr147=)
n.873-2A>G
c.421-2A>G (n.421-2A>G)
c.499-2A>G (n.499-2A>G)
c.610-2A>G (n.610-2A>G)
c.522A>G (p.Thr174=)
 gnomAD v4
19g.1106398A>TCA402939600GPX4c.613-2A>T (n.613-2A>T)
c.482-2A>T (n.482-2A>T)
c.496-2A>T (n.496-2A>T)
c.118-2A>T (n.118-2A>T)
c.502-2A>T (n.502-2A>T)
c.477-2A>T (n.477-2A>T)
c.235-2A>T (n.235-2A>T)
c.382-2A>T (n.382-2A>T)
c.441A>T (p.Thr147=)
n.873-2A>T
c.421-2A>T (n.421-2A>T)
c.499-2A>T (n.499-2A>T)
c.610-2A>T (n.610-2A>T)
c.522A>T (p.Thr174=)
19g.1106398_1106399delinsAGCA2317520638GPX4c.613-2_613-1delinsAG (n.613-2_613-1delinsAG)
c.482-2_482-1delinsAG (n.482-2_482-1delinsAG)
c.496-2_496-1delinsAG (n.496-2_496-1delinsAG)
c.118-2_118-1delinsAG (n.118-2_118-1delinsAG)
c.502-2_502-1delinsAG (n.502-2_502-1delinsAG)
c.477-2_477-1delinsAG (n.477-2_477-1delinsAG)
c.235-2_235-1delinsAG (n.235-2_235-1delinsAG)
c.382-2_382-1delinsAG (n.382-2_382-1delinsAG)
c.441_442delinsAG (p.Thr147=)
n.873-2_873-1delinsAG
c.421-2_421-1delinsAG (n.421-2_421-1delinsAG)
c.499-2_499-1delinsAG (n.499-2_499-1delinsAG)
c.610-2_610-1delinsAG (n.610-2_610-1delinsAG)
c.522_523delinsAG (p.Thr174=)
19g.1106399delCA658658763GPX4c.613-1del (n.613-1del)
c.482-1del (n.482-1del)
c.496-1del (n.496-1del)
c.118-1del (n.118-1del)
c.502-1del (n.502-1del)
c.477-1del (n.477-1del)
c.235-1del (n.235-1del)
c.382-1del (n.382-1del)
c.442del (p.Val148PhefsTer?)
n.873-1del
c.421-1del (n.421-1del)
c.499-1del (n.499-1del)
c.610-1del (n.610-1del)
c.523del (p.Val175PhefsTer?)
 ClinVar dbSNP
19g.1106399G>ACA402939601GPX4c.613-1G>A (n.613-1G>A)
c.482-1G>A (n.482-1G>A)
c.496-1G>A (n.496-1G>A)
c.118-1G>A (n.118-1G>A)
c.502-1G>A (n.502-1G>A)
c.477-1G>A (n.477-1G>A)
c.235-1G>A (n.235-1G>A)
c.382-1G>A (n.382-1G>A)
c.442G>A (p.Val148Ile)
n.873-1G>A
c.421-1G>A (n.421-1G>A)
c.499-1G>A (n.499-1G>A)
c.610-1G>A (n.610-1G>A)
c.523G>A (p.Val175Ile)
19g.1106399G>CCA402939606GPX4c.613-1G>C (n.613-1G>C)
c.482-1G>C (n.482-1G>C)
c.496-1G>C (n.496-1G>C)
c.118-1G>C (n.118-1G>C)
c.502-1G>C (n.502-1G>C)
c.477-1G>C (n.477-1G>C)
c.235-1G>C (n.235-1G>C)
c.382-1G>C (n.382-1G>C)
c.442G>C (p.Val148Leu)
n.873-1G>C
c.421-1G>C (n.421-1G>C)
c.499-1G>C (n.499-1G>C)
c.610-1G>C (n.610-1G>C)
c.523G>C (p.Val175Leu)
19g.1106399G>TCA402939604GPX4c.613-1G>T (n.613-1G>T)
c.482-1G>T (n.482-1G>T)
c.496-1G>T (n.496-1G>T)
c.118-1G>T (n.118-1G>T)
c.502-1G>T (n.502-1G>T)
c.477-1G>T (n.477-1G>T)
c.235-1G>T (n.235-1G>T)
c.382-1G>T (n.382-1G>T)
c.442G>T (p.Val148Phe)
n.873-1G>T
c.421-1G>T (n.421-1G>T)
c.499-1G>T (n.499-1G>T)
c.610-1G>T (n.610-1G>T)
c.523G>T (p.Val175Phe)
19g.1106400T>ACA402939608GPX4c.613T>A (p.Phe205Ile)
c.482T>A (p.Val161Asp)
c.496T>A (p.Phe166Ile)
c.118T>A (p.Phe40Ile)
c.502T>A (p.Phe168Ile)
c.477T>A (p.Asn159Lys)
c.235T>A (p.Phe79Ile)
c.382T>A (p.Phe128Ile)
c.443T>A (p.Val148Asp)
n.873T>A
c.421T>A (p.Phe141Ile)
c.499T>A (p.Phe167Ile)
c.610T>A (p.Phe204Ile)
c.524T>A (p.Val175Asp)
19g.1106400T>CCA402939611GPX4c.613T>C (p.Phe205Leu)
c.482T>C (p.Val161Ala)
c.496T>C (p.Phe166Leu)
c.118T>C (p.Phe40Leu)
c.502T>C (p.Phe168Leu)
c.477T>C (p.Asn159=)
c.235T>C (p.Phe79Leu)
c.382T>C (p.Phe128Leu)
c.443T>C (p.Val148Ala)
n.873T>C
c.421T>C (p.Phe141Leu)
c.499T>C (p.Phe167Leu)
c.610T>C (p.Phe204Leu)
c.524T>C (p.Val175Ala)
19g.1106400T>GCA402939614GPX4c.613T>G (p.Phe205Val)
c.482T>G (p.Val161Gly)
c.496T>G (p.Phe166Val)
c.118T>G (p.Phe40Val)
c.502T>G (p.Phe168Val)
c.477T>G (p.Asn159Lys)
c.235T>G (p.Phe79Val)
c.382T>G (p.Phe128Val)
c.443T>G (p.Val148Gly)
n.873T>G
c.421T>G (p.Phe141Val)
c.499T>G (p.Phe167Val)
c.610T>G (p.Phe204Val)
c.524T>G (p.Val175Gly)
19g.1106401T>ACA402939621GPX4c.614T>A (p.Phe205Tyr)
c.483T>A (p.Val161=)
c.497T>A (p.Phe166Tyr)
c.119T>A (p.Phe40Tyr)
c.503T>A (p.Phe168Tyr)
c.478T>A (p.Ser160Thr)
c.236T>A (p.Phe79Tyr)
c.383T>A (p.Phe128Tyr)
c.444T>A (p.Val148=)
n.874T>A
c.422T>A (p.Phe141Tyr)
c.500T>A (p.Phe167Tyr)
c.611T>A (p.Phe204Tyr)
c.525T>A (p.Val175=)
19g.1106401T>CCA402939622GPX4c.614T>C (p.Phe205Ser)
c.483T>C (p.Val161=)
c.497T>C (p.Phe166Ser)
c.119T>C (p.Phe40Ser)
c.503T>C (p.Phe168Ser)
c.478T>C (p.Ser160Pro)
c.236T>C (p.Phe79Ser)
c.383T>C (p.Phe128Ser)
c.444T>C (p.Val148=)
n.874T>C
c.422T>C (p.Phe141Ser)
c.500T>C (p.Phe167Ser)
c.611T>C (p.Phe204Ser)
c.525T>C (p.Val175=)
19g.1106401T>GCA402939625GPX4c.614T>G (p.Phe205Cys)
c.483T>G (p.Val161=)
c.497T>G (p.Phe166Cys)
c.119T>G (p.Phe40Cys)
c.503T>G (p.Phe168Cys)
c.478T>G (p.Ser160Ala)
c.236T>G (p.Phe79Cys)
c.383T>G (p.Phe128Cys)
c.444T>G (p.Val148=)
n.874T>G
c.422T>G (p.Phe141Cys)
c.500T>G (p.Phe167Cys)
c.611T>G (p.Phe204Cys)
c.525T>G (p.Val175=)
19g.1106402C>ACA402939630GPX4c.615C>A (p.Phe205Leu)
c.484C>A (p.Pro162Thr)
c.498C>A (p.Phe166Leu)
c.120C>A (p.Phe40Leu)
c.504C>A (p.Phe168Leu)
c.479C>A (p.Ser160Tyr)
c.237C>A (p.Phe79Leu)
c.384C>A (p.Phe128Leu)
c.445C>A (p.Pro149Thr)
n.875C>A
c.423C>A (p.Phe141Leu)
c.501C>A (p.Phe167Leu)
c.612C>A (p.Phe204Leu)
c.526C>A (p.Pro176Thr)
 gnomAD v4
19g.1106402C=CA2317520639GPX4c.615C= (p.Phe205=)
c.484C= (p.Pro162=)
c.498C= (p.Phe166=)
c.120C= (p.Phe40=)
c.504C= (p.Phe168=)
c.479C= (p.Ser160=)
c.237C= (p.Phe79=)
c.384C= (p.Phe128=)
c.445C= (p.Pro149=)
n.875C=
c.423C= (p.Phe141=)
c.501C= (p.Phe167=)
c.612C= (p.Phe204=)
c.526C= (p.Pro176=)
19g.1106402C>GCA402939634GPX4c.615C>G (p.Phe205Leu)
c.484C>G (p.Pro162Ala)
c.498C>G (p.Phe166Leu)
c.120C>G (p.Phe40Leu)
c.504C>G (p.Phe168Leu)
c.479C>G (p.Ser160Cys)
c.237C>G (p.Phe79Leu)
c.384C>G (p.Phe128Leu)
c.445C>G (p.Pro149Ala)
n.875C>G
c.423C>G (p.Phe141Leu)
c.501C>G (p.Phe167Leu)
c.612C>G (p.Phe204Leu)
c.526C>G (p.Pro176Ala)
 dbSNP gnomAD v2 gnomAD v4
19g.1106402C>TCA303994791GPX4c.615C>T (p.Phe205=)
c.484C>T (p.Pro162Ser)
c.498C>T (p.Phe166=)
c.120C>T (p.Phe40=)
c.504C>T (p.Phe168=)
c.479C>T (p.Ser160Phe)
c.237C>T (p.Phe79=)
c.384C>T (p.Phe128=)
c.445C>T (p.Pro149Ser)
n.875C>T
c.423C>T (p.Phe141=)
c.501C>T (p.Phe167=)
c.612C>T (p.Phe204=)
c.526C>T (p.Pro176Ser)
 ClinVar dbSNP gnomAD v2 gnomAD v3 gnomAD v4
19g.1106403C>ACA9037462GPX4c.616C>A (p.Leu206Ile)
c.485C>A (p.Pro162His)
c.499C>A (p.Leu167Ile)
c.121C>A (p.Leu41Ile)
c.505C>A (p.Leu169Ile)
c.480C>A (p.Ser160=)
c.238C>A (p.Leu80Ile)
c.385C>A (p.Leu129Ile)
c.446C>A (p.Pro149His)
n.876C>A
c.424C>A (p.Leu142Ile)
c.502C>A (p.Leu168Ile)
c.613C>A (p.Leu205Ile)
c.527C>A (p.Pro176His)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106403C=CA2317520641GPX4c.616C= (p.Leu206=)
c.485C= (p.Pro162=)
c.499C= (p.Leu167=)
c.121C= (p.Leu41=)
c.505C= (p.Leu169=)
c.480C= (p.Ser160=)
c.238C= (p.Leu80=)
c.385C= (p.Leu129=)
c.446C= (p.Pro149=)
n.876C=
c.424C= (p.Leu142=)
c.502C= (p.Leu168=)
c.613C= (p.Leu205=)
c.527C= (p.Pro176=)
19g.1106403C>GCA402939656GPX4c.616C>G (p.Leu206Val)
c.485C>G (p.Pro162Arg)
c.499C>G (p.Leu167Val)
c.121C>G (p.Leu41Val)
c.505C>G (p.Leu169Val)
c.480C>G (p.Ser160=)
c.238C>G (p.Leu80Val)
c.385C>G (p.Leu129Val)
c.446C>G (p.Pro149Arg)
n.876C>G
c.424C>G (p.Leu142Val)
c.502C>G (p.Leu168Val)
c.613C>G (p.Leu205Val)
c.527C>G (p.Pro176Arg)
19g.1106403C>TCA402939648GPX4c.616C>T (p.Leu206Phe)
c.485C>T (p.Pro162Leu)
c.499C>T (p.Leu167Phe)
c.121C>T (p.Leu41Phe)
c.505C>T (p.Leu169Phe)
c.480C>T (p.Ser160=)
c.238C>T (p.Leu80Phe)
c.385C>T (p.Leu129Phe)
c.446C>T (p.Pro149Leu)
n.876C>T
c.424C>T (p.Leu142Phe)
c.502C>T (p.Leu168Phe)
c.613C>T (p.Leu205Phe)
c.527C>T (p.Pro176Leu)
19g.1106403_1106406delinsCTCACA2317520640GPX4c.616_619delinsCTCA (p.Leu206=)
c.485_488delinsCTCA (p.Pro162=)
c.499_502delinsCTCA (p.Leu167=)
c.121_124delinsCTCA (p.Leu41=)
c.505_508delinsCTCA (p.Leu169=)
c.480_483delinsCTCA (p.Ser160=)
c.238_241delinsCTCA (p.Leu80=)
c.385_388delinsCTCA (p.Leu129=)
c.446_449delinsCTCA (p.Pro149=)
n.876_879delinsCTCA
c.424_427delinsCTCA (p.Leu142=)
c.502_505delinsCTCA (p.Leu168=)
c.613_616delinsCTCA (p.Leu205=)
c.527_530delinsCTCA (p.Pro176=)
19g.1106404T>ACA402939664GPX4c.617T>A (p.Leu206His)
c.486T>A (p.Pro162=)
c.500T>A (p.Leu167His)
c.122T>A (p.Leu41His)
c.506T>A (p.Leu169His)
c.481T>A (p.Ser161Thr)
c.239T>A (p.Leu80His)
c.386T>A (p.Leu129His)
c.447T>A (p.Pro149=)
n.877T>A
c.425T>A (p.Leu142His)
c.503T>A (p.Leu168His)
c.614T>A (p.Leu205His)
c.528T>A (p.Pro176=)
19g.1106404T>CCA402939667GPX4c.617T>C (p.Leu206Pro)
c.486T>C (p.Pro162=)
c.500T>C (p.Leu167Pro)
c.122T>C (p.Leu41Pro)
c.506T>C (p.Leu169Pro)
c.481T>C (p.Ser161Pro)
c.239T>C (p.Leu80Pro)
c.386T>C (p.Leu129Pro)
c.447T>C (p.Pro149=)
n.877T>C
c.425T>C (p.Leu142Pro)
c.503T>C (p.Leu168Pro)
c.614T>C (p.Leu205Pro)
c.528T>C (p.Pro176=)
19g.1106404T>GCA402939670GPX4c.617T>G (p.Leu206Arg)
c.486T>G (p.Pro162=)
c.500T>G (p.Leu167Arg)
c.122T>G (p.Leu41Arg)
c.506T>G (p.Leu169Arg)
c.481T>G (p.Ser161Ala)
c.239T>G (p.Leu80Arg)
c.386T>G (p.Leu129Arg)
c.447T>G (p.Pro149=)
n.877T>G
c.425T>G (p.Leu142Arg)
c.503T>G (p.Leu168Arg)
c.614T>G (p.Leu205Arg)
c.528T>G (p.Pro176=)
19g.1106406_1106408delCA9037461GPX4c.619_621del (p.Ile207del)
c.488_490del (p.His163del)
c.502_504del (p.Ile168del)
c.124_126del (p.Ile42del)
c.508_510del (p.Ile170del)
c.483_485del (p.Ser162del)
c.241_243del (p.Ile81del)
c.388_390del (p.Ile130del)
c.449_451del (p.His150del)
n.879_881del
c.427_429del (p.Ile143del)
c.505_507del (p.Ile169del)
c.616_618del (p.Ile206del)
c.530_532del (p.His177del)
 dbSNP ExAC gnomAD v4
19g.1106405C>ACA402939674GPX4c.618C>A (p.Leu206=)
c.487C>A (p.His163Asn)
c.501C>A (p.Leu167=)
c.123C>A (p.Leu41=)
c.507C>A (p.Leu169=)
c.482C>A (p.Ser161Ter)
c.240C>A (p.Leu80=)
c.387C>A (p.Leu129=)
c.448C>A (p.His150Asn)
n.878C>A
c.426C>A (p.Leu142=)
c.504C>A (p.Leu168=)
c.615C>A (p.Leu205=)
c.529C>A (p.His177Asn)
19g.1106405C>GCA402939672GPX4c.618C>G (p.Leu206=)
c.487C>G (p.His163Asp)
c.501C>G (p.Leu167=)
c.123C>G (p.Leu41=)
c.507C>G (p.Leu169=)
c.482C>G (p.Ser161Ter)
c.240C>G (p.Leu80=)
c.387C>G (p.Leu129=)
c.448C>G (p.His150Asp)
n.878C>G
c.426C>G (p.Leu142=)
c.504C>G (p.Leu168=)
c.615C>G (p.Leu205=)
c.529C>G (p.His177Asp)
19g.1106405C>TCA402939671GPX4c.618C>T (p.Leu206=)
c.487C>T (p.His163Tyr)
c.501C>T (p.Leu167=)
c.123C>T (p.Leu41=)
c.507C>T (p.Leu169=)
c.482C>T (p.Ser161Leu)
c.240C>T (p.Leu80=)
c.387C>T (p.Leu129=)
c.448C>T (p.His150Tyr)
n.878C>T
c.426C>T (p.Leu142=)
c.504C>T (p.Leu168=)
c.615C>T (p.Leu205=)
c.529C>T (p.His177Tyr)
 gnomAD v4
19g.1106406A=CA2317520642GPX4c.619A= (p.Ile207=)
c.488A= (p.His163=)
c.502A= (p.Ile168=)
c.124A= (p.Ile42=)
c.508A= (p.Ile170=)
c.483A= (p.Ser161=)
c.241A= (p.Ile81=)
c.388A= (p.Ile130=)
c.449A= (p.His150=)
n.879A=
c.427A= (p.Ile143=)
c.505A= (p.Ile169=)
c.616A= (p.Ile206=)
c.530A= (p.His177=)
19g.1106406A>CCA402939681GPX4c.619A>C (p.Ile207Leu)
c.488A>C (p.His163Pro)
c.502A>C (p.Ile168Leu)
c.124A>C (p.Ile42Leu)
c.508A>C (p.Ile170Leu)
c.483A>C (p.Ser161=)
c.241A>C (p.Ile81Leu)
c.388A>C (p.Ile130Leu)
c.449A>C (p.His150Pro)
n.879A>C
c.427A>C (p.Ile143Leu)
c.505A>C (p.Ile169Leu)
c.616A>C (p.Ile206Leu)
c.530A>C (p.His177Pro)
 gnomAD v4
19g.1106406A>GCA303994815GPX4c.619A>G (p.Ile207Val)
c.488A>G (p.His163Arg)
c.502A>G (p.Ile168Val)
c.124A>G (p.Ile42Val)
c.508A>G (p.Ile170Val)
c.483A>G (p.Ser161=)
c.241A>G (p.Ile81Val)
c.388A>G (p.Ile130Val)
c.449A>G (p.His150Arg)
n.879A>G
c.427A>G (p.Ile143Val)
c.505A>G (p.Ile169Val)
c.616A>G (p.Ile206Val)
c.530A>G (p.His177Arg)
 dbSNP gnomAD v4
19g.1106406A>TCA402939691GPX4c.619A>T (p.Ile207Phe)
c.488A>T (p.His163Leu)
c.502A>T (p.Ile168Phe)
c.124A>T (p.Ile42Phe)
c.508A>T (p.Ile170Phe)
c.483A>T (p.Ser161=)
c.241A>T (p.Ile81Phe)
c.388A>T (p.Ile130Phe)
c.449A>T (p.His150Leu)
n.879A>T
c.427A>T (p.Ile143Phe)
c.505A>T (p.Ile169Phe)
c.616A>T (p.Ile206Phe)
c.530A>T (p.His177Leu)
19g.1106406_1106408delinsATCCA2317520643GPX4c.619_621delinsATC (p.Ile207=)
c.488_490delinsATC (p.His163=)
c.502_504delinsATC (p.Ile168=)
c.124_126delinsATC (p.Ile42=)
c.508_510delinsATC (p.Ile170=)
c.483_485delinsATC (p.Ser161=)
c.241_243delinsATC (p.Ile81=)
c.388_390delinsATC (p.Ile130=)
c.449_451delinsATC (p.His150=)
n.879_881delinsATC
c.427_429delinsATC (p.Ile143=)
c.505_507delinsATC (p.Ile169=)
c.616_618delinsATC (p.Ile206=)
c.530_532delinsATC (p.His177=)
19g.1106407T>ACA402939697GPX4c.620T>A (p.Ile207Asn)
c.489T>A (p.His163Gln)
c.503T>A (p.Ile168Asn)
c.125T>A (p.Ile42Asn)
c.509T>A (p.Ile170Asn)
c.484T>A (p.Ser162Thr)
c.242T>A (p.Ile81Asn)
c.389T>A (p.Ile130Asn)
c.450T>A (p.His150Gln)
n.880T>A
c.428T>A (p.Ile143Asn)
c.506T>A (p.Ile169Asn)
c.617T>A (p.Ile206Asn)
c.531T>A (p.His177Gln)
19g.1106407T>CCA402939701GPX4c.620T>C (p.Ile207Thr)
c.489T>C (p.His163=)
c.503T>C (p.Ile168Thr)
c.125T>C (p.Ile42Thr)
c.509T>C (p.Ile170Thr)
c.484T>C (p.Ser162Pro)
c.242T>C (p.Ile81Thr)
c.389T>C (p.Ile130Thr)
c.450T>C (p.His150=)
n.880T>C
c.428T>C (p.Ile143Thr)
c.506T>C (p.Ile169Thr)
c.617T>C (p.Ile206Thr)
c.531T>C (p.His177=)
 gnomAD v4
19g.1106407T>GCA402939706GPX4c.620T>G (p.Ile207Ser)
c.489T>G (p.His163Gln)
c.503T>G (p.Ile168Ser)
c.125T>G (p.Ile42Ser)
c.509T>G (p.Ile170Ser)
c.484T>G (p.Ser162Ala)
c.242T>G (p.Ile81Ser)
c.389T>G (p.Ile130Ser)
c.450T>G (p.His150Gln)
n.880T>G
c.428T>G (p.Ile143Ser)
c.506T>G (p.Ile169Ser)
c.617T>G (p.Ile206Ser)
c.531T>G (p.His177Gln)
19g.1106407_1106408delCA1139666154GPX4c.620_621del (p.Ile207ArgfsTer?)
c.489_490del (p.His163GlnfsTer8)
c.503_504del (p.Ile168ArgfsTer?)
c.125_126del (p.Ile42ArgfsTer?)
c.509_510del (p.Ile170ArgfsTer?)
c.484_485del (p.Ser162AspfsTer28)
c.242_243del (p.Ile81ArgfsTer?)
c.389_390del (p.Ile130ArgfsTer?)
c.450_451del (p.His150GlnfsTer8)
n.880_881del
c.428_429del (p.Ile143ArgfsTer?)
c.506_507del (p.Ile169ArgfsTer?)
c.617_618del (p.Ile206ArgfsTer?)
c.531_532del (p.His177GlnfsTer8)
 ClinVar dbSNP
19g.1106408C>ACA402939713GPX4c.621C>A (p.Ile207=)
c.490C>A (p.Arg164=)
c.504C>A (p.Ile168=)
c.126C>A (p.Ile42=)
c.510C>A (p.Ile170=)
c.485C>A (p.Ser162Ter)
c.243C>A (p.Ile81=)
c.390C>A (p.Ile130=)
c.451C>A (p.Arg151=)
n.881C>A
c.429C>A (p.Ile143=)
c.507C>A (p.Ile169=)
c.618C>A (p.Ile206=)
c.532C>A (p.Arg178=)
 dbSNP gnomAD v2 gnomAD v4
19g.1106408C=CA2317520644GPX4c.621C= (p.Ile207=)
c.490C= (p.Arg164=)
c.504C= (p.Ile168=)
c.126C= (p.Ile42=)
c.510C= (p.Ile170=)
c.485C= (p.Ser162=)
c.243C= (p.Ile81=)
c.390C= (p.Ile130=)
c.451C= (p.Arg151=)
n.881C=
c.429C= (p.Ile143=)
c.507C= (p.Ile169=)
c.618C= (p.Ile206=)
c.532C= (p.Arg178=)
19g.1106408C>GCA9037464GPX4c.621C>G (p.Ile207Met)
c.490C>G (p.Arg164Gly)
c.504C>G (p.Ile168Met)
c.126C>G (p.Ile42Met)
c.510C>G (p.Ile170Met)
c.485C>G (p.Ser162Trp)
c.243C>G (p.Ile81Met)
c.390C>G (p.Ile130Met)
c.451C>G (p.Arg151Gly)
n.881C>G
c.429C>G (p.Ile143Met)
c.507C>G (p.Ile169Met)
c.618C>G (p.Ile206Met)
c.532C>G (p.Arg178Gly)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106408C>TCA9037463GPX4c.621C>T (p.Ile207=)
c.490C>T (p.Arg164Ter)
c.504C>T (p.Ile168=)
c.126C>T (p.Ile42=)
c.510C>T (p.Ile170=)
c.485C>T (p.Ser162Leu)
c.243C>T (p.Ile81=)
c.390C>T (p.Ile130=)
c.451C>T (p.Arg151Ter)
n.881C>T
c.429C>T (p.Ile143=)
c.507C>T (p.Ile169=)
c.618C>T (p.Ile206=)
c.532C>T (p.Arg178Ter)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4 COSMIC
19g.1106409G>ACA9037466GPX4c.622G>A (p.Asp208Asn)
c.491G>A (p.Arg164Gln)
c.505G>A (p.Asp169Asn)
c.127G>A (p.Asp43Asn)
c.511G>A (p.Asp171Asn)
c.486G>A (p.Ser162=)
c.244G>A (p.Asp82Asn)
c.391G>A (p.Asp131Asn)
c.452G>A (p.Arg151Gln)
n.882G>A
c.430G>A (p.Asp144Asn)
c.508G>A (p.Asp170Asn)
c.619G>A (p.Asp207Asn)
c.533G>A (p.Arg178Gln)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106409G>CCA9037465GPX4c.622G>C (p.Asp208His)
c.491G>C (p.Arg164Pro)
c.505G>C (p.Asp169His)
c.127G>C (p.Asp43His)
c.511G>C (p.Asp171His)
c.486G>C (p.Ser162=)
c.244G>C (p.Asp82His)
c.391G>C (p.Asp131His)
c.452G>C (p.Arg151Pro)
n.882G>C
c.430G>C (p.Asp144His)
c.508G>C (p.Asp170His)
c.619G>C (p.Asp207His)
c.533G>C (p.Arg178Pro)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106409G=CA2317520645GPX4c.622G= (p.Asp208=)
c.491G= (p.Arg164=)
c.505G= (p.Asp169=)
c.127G= (p.Asp43=)
c.511G= (p.Asp171=)
c.486G= (p.Ser162=)
c.244G= (p.Asp82=)
c.391G= (p.Asp131=)
c.452G= (p.Arg151=)
n.882G=
c.430G= (p.Asp144=)
c.508G= (p.Asp170=)
c.619G= (p.Asp207=)
c.533G= (p.Arg178=)
19g.1106409G>TCA402939732GPX4c.622G>T (p.Asp208Tyr)
c.491G>T (p.Arg164Leu)
c.505G>T (p.Asp169Tyr)
c.127G>T (p.Asp43Tyr)
c.511G>T (p.Asp171Tyr)
c.486G>T (p.Ser162=)
c.244G>T (p.Asp82Tyr)
c.391G>T (p.Asp131Tyr)
c.452G>T (p.Arg151Leu)
n.882G>T
c.430G>T (p.Asp144Tyr)
c.508G>T (p.Asp170Tyr)
c.619G>T (p.Asp207Tyr)
c.533G>T (p.Arg178Leu)
 gnomAD v4
19g.1106410A=CA2317520646GPX4c.623A= (p.Asp208=)
c.492A= (p.Arg164=)
c.506A= (p.Asp169=)
c.128A= (p.Asp43=)
c.512A= (p.Asp171=)
c.487A= (p.Thr163=)
c.245A= (p.Asp82=)
c.392A= (p.Asp131=)
c.453A= (p.Arg151=)
n.883A=
c.431A= (p.Asp144=)
c.509A= (p.Asp170=)
c.620A= (p.Asp207=)
c.534A= (p.Arg178=)
19g.1106410A>CCA402939736GPX4c.623A>C (p.Asp208Ala)
c.492A>C (p.Arg164=)
c.506A>C (p.Asp169Ala)
c.128A>C (p.Asp43Ala)
c.512A>C (p.Asp171Ala)
c.487A>C (p.Thr163Pro)
c.245A>C (p.Asp82Ala)
c.392A>C (p.Asp131Ala)
c.453A>C (p.Arg151=)
n.883A>C
c.431A>C (p.Asp144Ala)
c.509A>C (p.Asp170Ala)
c.620A>C (p.Asp207Ala)
c.534A>C (p.Arg178=)
19g.1106410A>GCA9037467GPX4c.623A>G (p.Asp208Gly)
c.492A>G (p.Arg164=)
c.506A>G (p.Asp169Gly)
c.128A>G (p.Asp43Gly)
c.512A>G (p.Asp171Gly)
c.487A>G (p.Thr163Ala)
c.245A>G (p.Asp82Gly)
c.392A>G (p.Asp131Gly)
c.453A>G (p.Arg151=)
n.883A>G
c.431A>G (p.Asp144Gly)
c.509A>G (p.Asp170Gly)
c.620A>G (p.Asp207Gly)
c.534A>G (p.Arg178=)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106410A>TCA402939742GPX4c.623A>T (p.Asp208Val)
c.492A>T (p.Arg164=)
c.506A>T (p.Asp169Val)
c.128A>T (p.Asp43Val)
c.512A>T (p.Asp171Val)
c.487A>T (p.Thr163Ser)
c.245A>T (p.Asp82Val)
c.392A>T (p.Asp131Val)
c.453A>T (p.Arg151=)
n.883A>T
c.431A>T (p.Asp144Val)
c.509A>T (p.Asp170Val)
c.620A>T (p.Asp207Val)
c.534A>T (p.Arg178=)
19g.1106411C>ACA402939748GPX4c.624C>A (p.Asp208Glu)
c.493C>A (p.Gln165Lys)
c.507C>A (p.Asp169Glu)
c.129C>A (p.Asp43Glu)
c.513C>A (p.Asp171Glu)
c.488C>A (p.Thr163Lys)
c.246C>A (p.Asp82Glu)
c.393C>A (p.Asp131Glu)
c.454C>A (p.Gln152Lys)
n.884C>A
c.432C>A (p.Asp144Glu)
c.510C>A (p.Asp170Glu)
c.621C>A (p.Asp207Glu)
c.535C>A (p.Gln179Lys)
19g.1106411C=CA2317520647GPX4c.624C= (p.Asp208=)
c.493C= (p.Gln165=)
c.507C= (p.Asp169=)
c.129C= (p.Asp43=)
c.513C= (p.Asp171=)
c.488C= (p.Thr163=)
c.246C= (p.Asp82=)
c.393C= (p.Asp131=)
c.454C= (p.Gln152=)
n.884C=
c.432C= (p.Asp144=)
c.510C= (p.Asp170=)
c.621C= (p.Asp207=)
c.535C= (p.Gln179=)
19g.1106411C>GCA402939752GPX4c.624C>G (p.Asp208Glu)
c.493C>G (p.Gln165Glu)
c.507C>G (p.Asp169Glu)
c.129C>G (p.Asp43Glu)
c.513C>G (p.Asp171Glu)
c.488C>G (p.Thr163Arg)
c.246C>G (p.Asp82Glu)
c.393C>G (p.Asp131Glu)
c.454C>G (p.Gln152Glu)
n.884C>G
c.432C>G (p.Asp144Glu)
c.510C>G (p.Asp170Glu)
c.621C>G (p.Asp207Glu)
c.535C>G (p.Gln179Glu)
 dbSNP gnomAD v2 gnomAD v4
19g.1106411C>TCA402939755GPX4c.624C>T (p.Asp208=)
c.493C>T (p.Gln165Ter)
c.507C>T (p.Asp169=)
c.129C>T (p.Asp43=)
c.513C>T (p.Asp171=)
c.488C>T (p.Thr163Ile)
c.246C>T (p.Asp82=)
c.393C>T (p.Asp131=)
c.454C>T (p.Gln152Ter)
n.884C>T
c.432C>T (p.Asp144=)
c.510C>T (p.Asp170=)
c.621C>T (p.Asp207=)
c.535C>T (p.Gln179Ter)
 dbSNP gnomAD v2 gnomAD v4
19g.1106412A>CCA402939761GPX4c.625A>C (p.Lys209Gln)
c.494A>C (p.Gln165Pro)
c.508A>C (p.Lys170Gln)
c.130A>C (p.Lys44Gln)
c.514A>C (p.Lys172Gln)
c.489A>C (p.Thr163=)
c.247A>C (p.Lys83Gln)
c.394A>C (p.Lys132Gln)
c.455A>C (p.Gln152Pro)
n.885A>C
c.433A>C (p.Lys145Gln)
c.511A>C (p.Lys171Gln)
c.622A>C (p.Lys208Gln)
c.536A>C (p.Gln179Pro)
19g.1106412A>GCA402939764GPX4c.625A>G (p.Lys209Glu)
c.494A>G (p.Gln165Arg)
c.508A>G (p.Lys170Glu)
c.130A>G (p.Lys44Glu)
c.514A>G (p.Lys172Glu)
c.489A>G (p.Thr163=)
c.247A>G (p.Lys83Glu)
c.394A>G (p.Lys132Glu)
c.455A>G (p.Gln152Arg)
n.885A>G
c.433A>G (p.Lys145Glu)
c.511A>G (p.Lys171Glu)
c.622A>G (p.Lys208Glu)
c.536A>G (p.Gln179Arg)
19g.1106412A>TCA402939767GPX4c.625A>T (p.Lys209Ter)
c.494A>T (p.Gln165Leu)
c.508A>T (p.Lys170Ter)
c.130A>T (p.Lys44Ter)
c.514A>T (p.Lys172Ter)
c.489A>T (p.Thr163=)
c.247A>T (p.Lys83Ter)
c.394A>T (p.Lys132Ter)
c.455A>T (p.Gln152Leu)
n.885A>T
c.433A>T (p.Lys145Ter)
c.511A>T (p.Lys171Ter)
c.622A>T (p.Lys208Ter)
c.536A>T (p.Gln179Leu)
19g.1106413A=CA2317520648GPX4c.626A= (p.Lys209=)
c.495A= (p.Gln165=)
c.509A= (p.Lys170=)
c.131A= (p.Lys44=)
c.515A= (p.Lys172=)
c.490A= (p.Arg164=)
c.248A= (p.Lys83=)
c.395A= (p.Lys132=)
c.456A= (p.Gln152=)
n.886A=
c.434A= (p.Lys145=)
c.512A= (p.Lys171=)
c.623A= (p.Lys208=)
c.537A= (p.Gln179=)
19g.1106413A>CCA9037468GPX4c.626A>C (p.Lys209Thr)
c.495A>C (p.Gln165His)
c.509A>C (p.Lys170Thr)
c.131A>C (p.Lys44Thr)
c.515A>C (p.Lys172Thr)
c.490A>C (p.Arg164=)
c.248A>C (p.Lys83Thr)
c.395A>C (p.Lys132Thr)
c.456A>C (p.Gln152His)
n.886A>C
c.434A>C (p.Lys145Thr)
c.512A>C (p.Lys171Thr)
c.623A>C (p.Lys208Thr)
c.537A>C (p.Gln179His)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106413A>GCA402939780GPX4c.626A>G (p.Lys209Arg)
c.495A>G (p.Gln165=)
c.509A>G (p.Lys170Arg)
c.131A>G (p.Lys44Arg)
c.515A>G (p.Lys172Arg)
c.490A>G (p.Arg164Gly)
c.248A>G (p.Lys83Arg)
c.395A>G (p.Lys132Arg)
c.456A>G (p.Gln152=)
n.886A>G
c.434A>G (p.Lys145Arg)
c.512A>G (p.Lys171Arg)
c.623A>G (p.Lys208Arg)
c.537A>G (p.Gln179=)
 dbSNP
19g.1106413A>TCA402939777GPX4c.626A>T (p.Lys209Met)
c.495A>T (p.Gln165His)
c.509A>T (p.Lys170Met)
c.131A>T (p.Lys44Met)
c.515A>T (p.Lys172Met)
c.490A>T (p.Arg164Ter)
c.248A>T (p.Lys83Met)
c.395A>T (p.Lys132Met)
c.456A>T (p.Gln152His)
n.886A>T
c.434A>T (p.Lys145Met)
c.512A>T (p.Lys171Met)
c.623A>T (p.Lys208Met)
c.537A>T (p.Gln179His)
19g.1106414_1106415delCA2576545169GPX4c.627_628del (p.Asn210ArgfsTer?)
c.496_497del (p.Glu166ThrfsTer5)
c.510_511del (p.Asn171ArgfsTer?)
c.132_133del (p.Asn45ArgfsTer?)
c.516_517del (p.Asn173ArgfsTer?)
c.491_492del (p.Arg164AsnfsTer26)
c.249_250del (p.Asn84ArgfsTer?)
c.396_397del (p.Asn133ArgfsTer?)
c.457_458del (p.Glu153ThrfsTer5)
n.887_888del
c.435_436del (p.Asn146ArgfsTer?)
c.513_514del (p.Asn172ArgfsTer?)
c.624_625del (p.Asn209ArgfsTer?)
c.538_539del (p.Glu180ThrfsTer5)
19g.1106413_1106414insTTCA9037469GPX4c.626_627insTT (p.Lys209AsnfsTer2)
c.495_496insTT (p.Glu166LeufsTer27)
c.509_510insTT (p.Lys170AsnfsTer2)
c.131_132insTT (p.Lys44AsnfsTer2)
c.515_516insTT (p.Lys172AsnfsTer2)
c.490_491insTT (p.Arg164IlefsTer?)
c.248_249insTT (p.Lys83AsnfsTer2)
c.395_396insTT (p.Lys132AsnfsTer2)
c.456_457insTT (p.Glu153LeufsTer27)
n.886_887insTT
c.495_496insTT (p.Glu166LeufsTer?)
c.434_435insTT (p.Lys145AsnfsTer2)
c.512_513insTT (p.Lys171AsnfsTer2)
c.623_624insTT (p.Lys208AsnfsTer2)
c.537_538insTT (p.Glu180LeufsTer27)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106414G>ACA9037470GPX4c.627G>A (p.Lys209=)
c.496G>A (p.Glu166Lys)
c.510G>A (p.Lys170=)
c.132G>A (p.Lys44=)
c.516G>A (p.Lys172=)
c.491G>A (p.Arg164Lys)
c.249G>A (p.Lys83=)
c.396G>A (p.Lys132=)
c.457G>A (p.Glu153Lys)
n.887G>A
c.435G>A (p.Lys145=)
c.513G>A (p.Lys171=)
c.624G>A (p.Lys208=)
c.538G>A (p.Glu180Lys)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106414G>CCA402939798GPX4c.627G>C (p.Lys209Asn)
c.496G>C (p.Glu166Gln)
c.510G>C (p.Lys170Asn)
c.132G>C (p.Lys44Asn)
c.516G>C (p.Lys172Asn)
c.491G>C (p.Arg164Thr)
c.249G>C (p.Lys83Asn)
c.396G>C (p.Lys132Asn)
c.457G>C (p.Glu153Gln)
n.887G>C
c.435G>C (p.Lys145Asn)
c.513G>C (p.Lys171Asn)
c.624G>C (p.Lys208Asn)
c.538G>C (p.Glu180Gln)
 dbSNP gnomAD v3 gnomAD v4
19g.1106414G=CA2317520649GPX4c.627G= (p.Lys209=)
c.496G= (p.Glu166=)
c.510G= (p.Lys170=)
c.132G= (p.Lys44=)
c.516G= (p.Lys172=)
c.491G= (p.Arg164=)
c.249G= (p.Lys83=)
c.396G= (p.Lys132=)
c.457G= (p.Glu153=)
n.887G=
c.435G= (p.Lys145=)
c.513G= (p.Lys171=)
c.624G= (p.Lys208=)
c.538G= (p.Glu180=)
19g.1106414G>TCA402939805GPX4c.627G>T (p.Lys209Asn)
c.496G>T (p.Glu166Ter)
c.510G>T (p.Lys170Asn)
c.132G>T (p.Lys44Asn)
c.516G>T (p.Lys172Asn)
c.491G>T (p.Arg164Ile)
c.249G>T (p.Lys83Asn)
c.396G>T (p.Lys132Asn)
c.457G>T (p.Glu153Ter)
n.887G>T
c.435G>T (p.Lys145Asn)
c.513G>T (p.Lys171Asn)
c.624G>T (p.Lys208Asn)
c.538G>T (p.Glu180Ter)
 gnomAD v4
19g.1106415A=CA2317520650GPX4c.628A= (p.Asn210=)
c.497A= (p.Glu166=)
c.511A= (p.Asn171=)
c.133A= (p.Asn45=)
c.517A= (p.Asn173=)
c.492A= (p.Arg164=)
c.250A= (p.Asn84=)
c.397A= (p.Asn133=)
c.458A= (p.Glu153=)
n.888A=
c.436A= (p.Asn146=)
c.514A= (p.Asn172=)
c.625A= (p.Asn209=)
c.539A= (p.Glu180=)
19g.1106415A>CCA402939819GPX4c.628A>C (p.Asn210His)
c.497A>C (p.Glu166Ala)
c.511A>C (p.Asn171His)
c.133A>C (p.Asn45His)
c.517A>C (p.Asn173His)
c.492A>C (p.Arg164Ser)
c.250A>C (p.Asn84His)
c.397A>C (p.Asn133His)
c.458A>C (p.Glu153Ala)
n.888A>C
c.436A>C (p.Asn146His)
c.514A>C (p.Asn172His)
c.625A>C (p.Asn209His)
c.539A>C (p.Glu180Ala)
 dbSNP
19g.1106415A>GCA402939824GPX4c.628A>G (p.Asn210Asp)
c.497A>G (p.Glu166Gly)
c.511A>G (p.Asn171Asp)
c.133A>G (p.Asn45Asp)
c.517A>G (p.Asn173Asp)
c.492A>G (p.Arg164=)
c.250A>G (p.Asn84Asp)
c.397A>G (p.Asn133Asp)
c.458A>G (p.Glu153Gly)
n.888A>G
c.436A>G (p.Asn146Asp)
c.514A>G (p.Asn172Asp)
c.625A>G (p.Asn209Asp)
c.539A>G (p.Glu180Gly)
19g.1106415A>TCA402939837GPX4c.628A>T (p.Asn210Tyr)
c.497A>T (p.Glu166Val)
c.511A>T (p.Asn171Tyr)
c.133A>T (p.Asn45Tyr)
c.517A>T (p.Asn173Tyr)
c.492A>T (p.Arg164Ser)
c.250A>T (p.Asn84Tyr)
c.397A>T (p.Asn133Tyr)
c.458A>T (p.Glu153Val)
n.888A>T
c.436A>T (p.Asn146Tyr)
c.514A>T (p.Asn172Tyr)
c.625A>T (p.Asn209Tyr)
c.539A>T (p.Glu180Val)
19g.1106416A>CCA402939843GPX4c.629A>C (p.Asn210Thr)
c.498A>C (p.Glu166Asp)
c.512A>C (p.Asn171Thr)
c.134A>C (p.Asn45Thr)
c.518A>C (p.Asn173Thr)
c.493A>C (p.Thr165Pro)
c.251A>C (p.Asn84Thr)
c.398A>C (p.Asn133Thr)
c.459A>C (p.Glu153Asp)
n.889A>C
c.437A>C (p.Asn146Thr)
c.515A>C (p.Asn172Thr)
c.626A>C (p.Asn209Thr)
c.540A>C (p.Glu180Asp)
19g.1106416A>GCA402939842GPX4c.629A>G (p.Asn210Ser)
c.498A>G (p.Glu166=)
c.512A>G (p.Asn171Ser)
c.134A>G (p.Asn45Ser)
c.518A>G (p.Asn173Ser)
c.493A>G (p.Thr165Ala)
c.251A>G (p.Asn84Ser)
c.398A>G (p.Asn133Ser)
c.459A>G (p.Glu153=)
n.889A>G
c.437A>G (p.Asn146Ser)
c.515A>G (p.Asn172Ser)
c.626A>G (p.Asn209Ser)
c.540A>G (p.Glu180=)
19g.1106416A>TCA402939841GPX4c.629A>T (p.Asn210Ile)
c.498A>T (p.Glu166Asp)
c.512A>T (p.Asn171Ile)
c.134A>T (p.Asn45Ile)
c.518A>T (p.Asn173Ile)
c.493A>T (p.Thr165Ser)
c.251A>T (p.Asn84Ile)
c.398A>T (p.Asn133Ile)
c.459A>T (p.Glu153Asp)
n.889A>T
c.437A>T (p.Asn146Ile)
c.515A>T (p.Asn172Ile)
c.626A>T (p.Asn209Ile)
c.540A>T (p.Glu180Asp)
19g.1106417C>ACA402939844GPX4c.630C>A (p.Asn210Lys)
c.499C>A (p.Arg167=)
c.513C>A (p.Asn171Lys)
c.135C>A (p.Asn45Lys)
c.519C>A (p.Asn173Lys)
c.494C>A (p.Thr165Lys)
c.252C>A (p.Asn84Lys)
c.399C>A (p.Asn133Lys)
c.460C>A (p.Arg154=)
n.890C>A
c.438C>A (p.Asn146Lys)
c.516C>A (p.Asn172Lys)
c.627C>A (p.Asn209Lys)
c.541C>A (p.Arg181=)
 dbSNP gnomAD v2 gnomAD v4
19g.1106417C=CA2317520651GPX4c.630C= (p.Asn210=)
c.499C= (p.Arg167=)
c.513C= (p.Asn171=)
c.135C= (p.Asn45=)
c.519C= (p.Asn173=)
c.494C= (p.Thr165=)
c.252C= (p.Asn84=)
c.399C= (p.Asn133=)
c.460C= (p.Arg154=)
n.890C=
c.438C= (p.Asn146=)
c.516C= (p.Asn172=)
c.627C= (p.Asn209=)
c.541C= (p.Arg181=)
19g.1106417C>GCA402939845GPX4c.630C>G (p.Asn210Lys)
c.499C>G (p.Arg167Gly)
c.513C>G (p.Asn171Lys)
c.135C>G (p.Asn45Lys)
c.519C>G (p.Asn173Lys)
c.494C>G (p.Thr165Arg)
c.252C>G (p.Asn84Lys)
c.399C>G (p.Asn133Lys)
c.460C>G (p.Arg154Gly)
n.890C>G
c.438C>G (p.Asn146Lys)
c.516C>G (p.Asn172Lys)
c.627C>G (p.Asn209Lys)
c.541C>G (p.Arg181Gly)
19g.1106417C>TCA9037471GPX4c.630C>T (p.Asn210=)
c.499C>T (p.Arg167Trp)
c.513C>T (p.Asn171=)
c.135C>T (p.Asn45=)
c.519C>T (p.Asn173=)
c.494C>T (p.Thr165Met)
c.252C>T (p.Asn84=)
c.399C>T (p.Asn133=)
c.460C>T (p.Arg154Trp)
n.890C>T
c.438C>T (p.Asn146=)
c.516C>T (p.Asn172=)
c.627C>T (p.Asn209=)
c.541C>T (p.Arg181Trp)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106418G>ACA9037472GPX4c.631G>A (p.Gly211Ser)
c.500G>A (p.Arg167Gln)
c.514G>A (p.Gly172Ser)
c.136G>A (p.Gly46Ser)
c.520G>A (p.Gly174Ser)
c.495G>A (p.Thr165=)
c.253G>A (p.Gly85Ser)
c.400G>A (p.Gly134Ser)
c.461G>A (p.Arg154Gln)
n.891G>A
c.439G>A (p.Gly147Ser)
c.517G>A (p.Gly173Ser)
c.628G>A (p.Gly210Ser)
c.542G>A (p.Arg181Gln)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106418G>CCA402939848GPX4c.631G>C (p.Gly211Arg)
c.500G>C (p.Arg167Pro)
c.514G>C (p.Gly172Arg)
c.136G>C (p.Gly46Arg)
c.520G>C (p.Gly174Arg)
c.495G>C (p.Thr165=)
c.253G>C (p.Gly85Arg)
c.400G>C (p.Gly134Arg)
c.461G>C (p.Arg154Pro)
n.891G>C
c.439G>C (p.Gly147Arg)
c.517G>C (p.Gly173Arg)
c.628G>C (p.Gly210Arg)
c.542G>C (p.Arg181Pro)
 gnomAD v4
19g.1106418G=CA2317520652GPX4c.631G= (p.Gly211=)
c.500G= (p.Arg167=)
c.514G= (p.Gly172=)
c.136G= (p.Gly46=)
c.520G= (p.Gly174=)
c.495G= (p.Thr165=)
c.253G= (p.Gly85=)
c.400G= (p.Gly134=)
c.461G= (p.Arg154=)
n.891G=
c.439G= (p.Gly147=)
c.517G= (p.Gly173=)
c.628G= (p.Gly210=)
c.542G= (p.Arg181=)
19g.1106418G>TCA402939849GPX4c.631G>T (p.Gly211Cys)
c.500G>T (p.Arg167Leu)
c.514G>T (p.Gly172Cys)
c.136G>T (p.Gly46Cys)
c.520G>T (p.Gly174Cys)
c.495G>T (p.Thr165=)
c.253G>T (p.Gly85Cys)
c.400G>T (p.Gly134Cys)
c.461G>T (p.Arg154Leu)
n.891G>T
c.439G>T (p.Gly147Cys)
c.517G>T (p.Gly173Cys)
c.628G>T (p.Gly210Cys)
c.542G>T (p.Arg181Leu)
 dbSNP gnomAD v2 gnomAD v4
19g.1106419G>ACA303994875GPX4c.632G>A (p.Gly211Asp)
c.501G>A (p.Arg167=)
c.515G>A (p.Gly172Asp)
c.137G>A (p.Gly46Asp)
c.521G>A (p.Gly174Asp)
c.496G>A (p.Ala166Thr)
c.254G>A (p.Gly85Asp)
c.401G>A (p.Gly134Asp)
c.462G>A (p.Arg154=)
n.892G>A
c.440G>A (p.Gly147Asp)
c.518G>A (p.Gly173Asp)
c.629G>A (p.Gly210Asp)
c.543G>A (p.Arg181=)
 dbSNP
19g.1106419G>CCA402939855GPX4c.632G>C (p.Gly211Ala)
c.501G>C (p.Arg167=)
c.515G>C (p.Gly172Ala)
c.137G>C (p.Gly46Ala)
c.521G>C (p.Gly174Ala)
c.496G>C (p.Ala166Pro)
c.254G>C (p.Gly85Ala)
c.401G>C (p.Gly134Ala)
c.462G>C (p.Arg154=)
n.892G>C
c.440G>C (p.Gly147Ala)
c.518G>C (p.Gly173Ala)
c.629G>C (p.Gly210Ala)
c.543G>C (p.Arg181=)
 gnomAD v4 COSMIC
19g.1106419G=CA2317520653GPX4c.632G= (p.Gly211=)
c.501G= (p.Arg167=)
c.515G= (p.Gly172=)
c.137G= (p.Gly46=)
c.521G= (p.Gly174=)
c.496G= (p.Ala166=)
c.254G= (p.Gly85=)
c.401G= (p.Gly134=)
c.462G= (p.Arg154=)
n.892G=
c.440G= (p.Gly147=)
c.518G= (p.Gly173=)
c.629G= (p.Gly210=)
c.543G= (p.Arg181=)
19g.1106419G>TCA402939853GPX4c.632G>T (p.Gly211Val)
c.501G>T (p.Arg167=)
c.515G>T (p.Gly172Val)
c.137G>T (p.Gly46Val)
c.521G>T (p.Gly174Val)
c.496G>T (p.Ala166Ser)
c.254G>T (p.Gly85Val)
c.401G>T (p.Gly134Val)
c.462G>T (p.Arg154=)
n.892G>T
c.440G>T (p.Gly147Val)
c.518G>T (p.Gly173Val)
c.629G>T (p.Gly210Val)
c.543G>T (p.Arg181=)
19g.1106420C>ACA402939859GPX4c.633C>A (p.Gly211=)
c.502C>A (p.Leu168Met)
c.516C>A (p.Gly172=)
c.138C>A (p.Gly46=)
c.522C>A (p.Gly174=)
c.497C>A (p.Ala166Asp)
c.255C>A (p.Gly85=)
c.402C>A (p.Gly134=)
c.463C>A (p.Leu155Met)
n.893C>A
c.441C>A (p.Gly147=)
c.519C>A (p.Gly173=)
c.630C>A (p.Gly210=)
c.544C>A (p.Leu182Met)
19g.1106420C=CA2317520654GPX4c.633C= (p.Gly211=)
c.502C= (p.Leu168=)
c.516C= (p.Gly172=)
c.138C= (p.Gly46=)
c.522C= (p.Gly174=)
c.497C= (p.Ala166=)
c.255C= (p.Gly85=)
c.402C= (p.Gly134=)
c.463C= (p.Leu155=)
n.893C=
c.441C= (p.Gly147=)
c.519C= (p.Gly173=)
c.630C= (p.Gly210=)
c.544C= (p.Leu182=)
19g.1106420C>GCA402939862GPX4c.633C>G (p.Gly211=)
c.502C>G (p.Leu168Val)
c.516C>G (p.Gly172=)
c.138C>G (p.Gly46=)
c.522C>G (p.Gly174=)
c.497C>G (p.Ala166Gly)
c.255C>G (p.Gly85=)
c.402C>G (p.Gly134=)
c.463C>G (p.Leu155Val)
n.893C>G
c.441C>G (p.Gly147=)
c.519C>G (p.Gly173=)
c.630C>G (p.Gly210=)
c.544C>G (p.Leu182Val)
 gnomAD v4
19g.1106420C>TCA9037473GPX4c.633C>T (p.Gly211=)
c.502C>T (p.Leu168=)
c.516C>T (p.Gly172=)
c.138C>T (p.Gly46=)
c.522C>T (p.Gly174=)
c.497C>T (p.Ala166Val)
c.255C>T (p.Gly85=)
c.402C>T (p.Gly134=)
c.463C>T (p.Leu155=)
n.893C>T
c.441C>T (p.Gly147=)
c.519C>T (p.Gly173=)
c.630C>T (p.Gly210=)
c.544C>T (p.Leu182=)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4 COSMIC
19g.1106421T>ACA402939868GPX4c.634T>A (p.Cys212Ser)
c.503T>A (p.Leu168Gln)
c.517T>A (p.Cys173Ser)
c.139T>A (p.Cys47Ser)
c.523T>A (p.Cys175Ser)
c.498T>A (p.Ala166=)
c.256T>A (p.Cys86Ser)
c.403T>A (p.Cys135Ser)
c.464T>A (p.Leu155Gln)
n.894T>A
c.442T>A (p.Cys148Ser)
c.520T>A (p.Cys174Ser)
c.631T>A (p.Cys211Ser)
c.545T>A (p.Leu182Gln)
19g.1106421T>CCA402939871GPX4c.634T>C (p.Cys212Arg)
c.503T>C (p.Leu168Pro)
c.517T>C (p.Cys173Arg)
c.139T>C (p.Cys47Arg)
c.523T>C (p.Cys175Arg)
c.498T>C (p.Ala166=)
c.256T>C (p.Cys86Arg)
c.403T>C (p.Cys135Arg)
c.464T>C (p.Leu155Pro)
n.894T>C
c.442T>C (p.Cys148Arg)
c.520T>C (p.Cys174Arg)
c.631T>C (p.Cys211Arg)
c.545T>C (p.Leu182Pro)
19g.1106421T>GCA402939873GPX4c.634T>G (p.Cys212Gly)
c.503T>G (p.Leu168Arg)
c.517T>G (p.Cys173Gly)
c.139T>G (p.Cys47Gly)
c.523T>G (p.Cys175Gly)
c.498T>G (p.Ala166=)
c.256T>G (p.Cys86Gly)
c.403T>G (p.Cys135Gly)
c.464T>G (p.Leu155Arg)
n.894T>G
c.442T>G (p.Cys148Gly)
c.520T>G (p.Cys174Gly)
c.631T>G (p.Cys211Gly)
c.545T>G (p.Leu182Arg)
19g.1106422G>ACA402939879GPX4c.635G>A (p.Cys212Tyr)
c.504G>A (p.Leu168=)
c.518G>A (p.Cys173Tyr)
c.140G>A (p.Cys47Tyr)
c.524G>A (p.Cys175Tyr)
c.499G>A (p.Ala167Thr)
c.257G>A (p.Cys86Tyr)
c.404G>A (p.Cys135Tyr)
c.465G>A (p.Leu155=)
n.895G>A
c.443G>A (p.Cys148Tyr)
c.521G>A (p.Cys174Tyr)
c.632G>A (p.Cys211Tyr)
c.546G>A (p.Leu182=)
 gnomAD v4
19g.1106422G>CCA303994885GPX4c.635G>C (p.Cys212Ser)
c.504G>C (p.Leu168=)
c.518G>C (p.Cys173Ser)
c.140G>C (p.Cys47Ser)
c.524G>C (p.Cys175Ser)
c.499G>C (p.Ala167Pro)
c.257G>C (p.Cys86Ser)
c.404G>C (p.Cys135Ser)
c.465G>C (p.Leu155=)
n.895G>C
c.443G>C (p.Cys148Ser)
c.521G>C (p.Cys174Ser)
c.632G>C (p.Cys211Ser)
c.546G>C (p.Leu182=)
 dbSNP gnomAD v4
19g.1106422G=CA2317520655GPX4c.635G= (p.Cys212=)
c.504G= (p.Leu168=)
c.518G= (p.Cys173=)
c.140G= (p.Cys47=)
c.524G= (p.Cys175=)
c.499G= (p.Ala167=)
c.257G= (p.Cys86=)
c.404G= (p.Cys135=)
c.465G= (p.Leu155=)
n.895G=
c.443G= (p.Cys148=)
c.521G= (p.Cys174=)
c.632G= (p.Cys211=)
c.546G= (p.Leu182=)
19g.1106422G>TCA303994889GPX4c.635G>T (p.Cys212Phe)
c.504G>T (p.Leu168=)
c.518G>T (p.Cys173Phe)
c.140G>T (p.Cys47Phe)
c.524G>T (p.Cys175Phe)
c.499G>T (p.Ala167Ser)
c.257G>T (p.Cys86Phe)
c.404G>T (p.Cys135Phe)
c.465G>T (p.Leu155=)
n.895G>T
c.443G>T (p.Cys148Phe)
c.521G>T (p.Cys174Phe)
c.632G>T (p.Cys211Phe)
c.546G>T (p.Leu182=)
 dbSNP gnomAD v4
19g.1106423C>ACA402939888GPX4c.636C>A (p.Cys212Ter)
c.505C>A (p.Arg169Ser)
c.519C>A (p.Cys173Ter)
c.141C>A (p.Cys47Ter)
c.525C>A (p.Cys175Ter)
c.500C>A (p.Ala167Glu)
c.258C>A (p.Cys86Ter)
c.405C>A (p.Cys135Ter)
c.466C>A (p.Arg156Ser)
n.896C>A
c.444C>A (p.Cys148Ter)
c.522C>A (p.Cys174Ter)
c.633C>A (p.Cys211Ter)
c.547C>A (p.Arg183Ser)
 gnomAD v4
19g.1106423C=CA2317520656GPX4c.636C= (p.Cys212=)
c.505C= (p.Arg169=)
c.519C= (p.Cys173=)
c.141C= (p.Cys47=)
c.525C= (p.Cys175=)
c.500C= (p.Ala167=)
c.258C= (p.Cys86=)
c.405C= (p.Cys135=)
c.466C= (p.Arg156=)
n.896C=
c.444C= (p.Cys148=)
c.522C= (p.Cys174=)
c.633C= (p.Cys211=)
c.547C= (p.Arg183=)
19g.1106423C>GCA402939892GPX4c.636C>G (p.Cys212Trp)
c.505C>G (p.Arg169Gly)
c.519C>G (p.Cys173Trp)
c.141C>G (p.Cys47Trp)
c.525C>G (p.Cys175Trp)
c.500C>G (p.Ala167Gly)
c.258C>G (p.Cys86Trp)
c.405C>G (p.Cys135Trp)
c.466C>G (p.Arg156Gly)
n.896C>G
c.444C>G (p.Cys148Trp)
c.522C>G (p.Cys174Trp)
c.633C>G (p.Cys211Trp)
c.547C>G (p.Arg183Gly)
19g.1106423C>TCA9037474GPX4c.636C>T (p.Cys212=)
c.505C>T (p.Arg169Cys)
c.519C>T (p.Cys173=)
c.141C>T (p.Cys47=)
c.525C>T (p.Cys175=)
c.500C>T (p.Ala167Val)
c.258C>T (p.Cys86=)
c.405C>T (p.Cys135=)
c.466C>T (p.Arg156Cys)
n.896C>T
c.444C>T (p.Cys148=)
c.522C>T (p.Cys174=)
c.633C>T (p.Cys211=)
c.547C>T (p.Arg183Cys)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106424G>ACA9037475GPX4c.637G>A (p.Val213Met)
c.506G>A (p.Arg169His)
c.520G>A (p.Val174Met)
c.142G>A (p.Val48Met)
c.526G>A (p.Val176Met)
c.501G>A (p.Ala167=)
c.259G>A (p.Val87Met)
c.406G>A (p.Val136Met)
c.467G>A (p.Arg156His)
n.897G>A
c.445G>A (p.Val149Met)
c.523G>A (p.Val175Met)
c.634G>A (p.Val212Met)
c.548G>A (p.Arg183His)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106424G>CCA402939902GPX4c.637G>C (p.Val213Leu)
c.506G>C (p.Arg169Pro)
c.520G>C (p.Val174Leu)
c.142G>C (p.Val48Leu)
c.526G>C (p.Val176Leu)
c.501G>C (p.Ala167=)
c.259G>C (p.Val87Leu)
c.406G>C (p.Val136Leu)
c.467G>C (p.Arg156Pro)
n.897G>C
c.445G>C (p.Val149Leu)
c.523G>C (p.Val175Leu)
c.634G>C (p.Val212Leu)
c.548G>C (p.Arg183Pro)
19g.1106424G=CA2317520657GPX4c.637G= (p.Val213=)
c.506G= (p.Arg169=)
c.520G= (p.Val174=)
c.142G= (p.Val48=)
c.526G= (p.Val176=)
c.501G= (p.Ala167=)
c.259G= (p.Val87=)
c.406G= (p.Val136=)
c.467G= (p.Arg156=)
n.897G=
c.445G= (p.Val149=)
c.523G= (p.Val175=)
c.634G= (p.Val212=)
c.548G= (p.Arg183=)
19g.1106424G>TCA402939898GPX4c.637G>T (p.Val213Leu)
c.506G>T (p.Arg169Leu)
c.520G>T (p.Val174Leu)
c.142G>T (p.Val48Leu)
c.526G>T (p.Val176Leu)
c.501G>T (p.Ala167=)
c.259G>T (p.Val87Leu)
c.406G>T (p.Val136Leu)
c.467G>T (p.Arg156Leu)
n.897G>T
c.445G>T (p.Val149Leu)
c.523G>T (p.Val175Leu)
c.634G>T (p.Val212Leu)
c.548G>T (p.Arg183Leu)
19g.1106425T>ACA402939907GPX4c.638T>A (p.Val213Glu)
c.507T>A (p.Arg169=)
c.521T>A (p.Val174Glu)
c.143T>A (p.Val48Glu)
c.527T>A (p.Val176Glu)
c.502T>A (p.Trp168Arg)
c.260T>A (p.Val87Glu)
c.407T>A (p.Val136Glu)
c.468T>A (p.Arg156=)
n.898T>A
c.446T>A (p.Val149Glu)
c.524T>A (p.Val175Glu)
c.635T>A (p.Val212Glu)
c.549T>A (p.Arg183=)
19g.1106425T>CCA402939910GPX4c.638T>C (p.Val213Ala)
c.507T>C (p.Arg169=)
c.521T>C (p.Val174Ala)
c.143T>C (p.Val48Ala)
c.527T>C (p.Val176Ala)
c.502T>C (p.Trp168Arg)
c.260T>C (p.Val87Ala)
c.407T>C (p.Val136Ala)
c.468T>C (p.Arg156=)
n.898T>C
c.446T>C (p.Val149Ala)
c.524T>C (p.Val175Ala)
c.635T>C (p.Val212Ala)
c.549T>C (p.Arg183=)
19g.1106425T>GCA402939913GPX4c.638T>G (p.Val213Gly)
c.507T>G (p.Arg169=)
c.521T>G (p.Val174Gly)
c.143T>G (p.Val48Gly)
c.527T>G (p.Val176Gly)
c.502T>G (p.Trp168Gly)
c.260T>G (p.Val87Gly)
c.407T>G (p.Val136Gly)
c.468T>G (p.Arg156=)
n.898T>G
c.446T>G (p.Val149Gly)
c.524T>G (p.Val175Gly)
c.635T>G (p.Val212Gly)
c.549T>G (p.Arg183=)
 gnomAD v4
19g.1106426G>ACA402939917GPX4c.639G>A (p.Val213=)
c.508G>A (p.Gly170Ser)
c.522G>A (p.Val174=)
c.144G>A (p.Val48=)
c.528G>A (p.Val176=)
c.503G>A (p.Trp168Ter)
c.261G>A (p.Val87=)
c.408G>A (p.Val136=)
c.469G>A (p.Gly157Ser)
n.899G>A
c.447G>A (p.Val149=)
c.525G>A (p.Val175=)
c.636G>A (p.Val212=)
c.550G>A (p.Gly184Ser)
19g.1106426G>CCA402939919GPX4c.639G>C (p.Val213=)
c.508G>C (p.Gly170Arg)
c.522G>C (p.Val174=)
c.144G>C (p.Val48=)
c.528G>C (p.Val176=)
c.503G>C (p.Trp168Ser)
c.261G>C (p.Val87=)
c.408G>C (p.Val136=)
c.469G>C (p.Gly157Arg)
n.899G>C
c.447G>C (p.Val149=)
c.525G>C (p.Val175=)
c.636G>C (p.Val212=)
c.550G>C (p.Gly184Arg)
19g.1106426G>TCA402939922GPX4c.639G>T (p.Val213=)
c.508G>T (p.Gly170Cys)
c.522G>T (p.Val174=)
c.144G>T (p.Val48=)
c.528G>T (p.Val176=)
c.503G>T (p.Trp168Leu)
c.261G>T (p.Val87=)
c.408G>T (p.Val136=)
c.469G>T (p.Gly157Cys)
n.899G>T
c.447G>T (p.Val149=)
c.525G>T (p.Val175=)
c.636G>T (p.Val212=)
c.550G>T (p.Gly184Cys)
 gnomAD v4
19g.1106427G>ACA402939924GPX4c.640G>A (p.Val214Met)
c.509G>A (p.Gly170Asp)
c.523G>A (p.Val175Met)
c.145G>A (p.Val49Met)
c.529G>A (p.Val177Met)
c.504G>A (p.Trp168Ter)
c.262G>A (p.Val88Met)
c.409G>A (p.Val137Met)
c.470G>A (p.Gly157Asp)
n.900G>A
c.448G>A (p.Val150Met)
c.526G>A (p.Val176Met)
c.637G>A (p.Val213Met)
c.551G>A (p.Gly184Asp)
19g.1106427G>CCA402939926GPX4c.640G>C (p.Val214Leu)
c.509G>C (p.Gly170Ala)
c.523G>C (p.Val175Leu)
c.145G>C (p.Val49Leu)
c.529G>C (p.Val177Leu)
c.504G>C (p.Trp168Cys)
c.262G>C (p.Val88Leu)
c.409G>C (p.Val137Leu)
c.470G>C (p.Gly157Ala)
n.900G>C
c.448G>C (p.Val150Leu)
c.526G>C (p.Val176Leu)
c.637G>C (p.Val213Leu)
c.551G>C (p.Gly184Ala)
19g.1106427G>TCA402939930GPX4c.640G>T (p.Val214Leu)
c.509G>T (p.Gly170Val)
c.523G>T (p.Val175Leu)
c.145G>T (p.Val49Leu)
c.529G>T (p.Val177Leu)
c.504G>T (p.Trp168Cys)
c.262G>T (p.Val88Leu)
c.409G>T (p.Val137Leu)
c.470G>T (p.Gly157Val)
n.900G>T
c.448G>T (p.Val150Leu)
c.526G>T (p.Val176Leu)
c.637G>T (p.Val213Leu)
c.551G>T (p.Gly184Val)
19g.1106430_1106431insCGCGTGACA2813238551GPX4c.643_644insCGCGTGA (p.Lys215ThrfsTer?)
c.512_513insCGCGTGA (p.Glu171AspfsTer3)
c.526_527insCGCGTGA (p.Lys176ThrfsTer?)
c.148_149insCGCGTGA (p.Lys50ThrfsTer?)
c.532_533insCGCGTGA (p.Lys178ThrfsTer?)
c.507_508insCGCGTGA (p.Ser170ArgfsTer23)
c.265_266insCGCGTGA (p.Lys89ThrfsTer?)
c.412_413insCGCGTGA (p.Lys138ThrfsTer?)
c.473_474insCGCGTGA (p.Glu158AspfsTer3)
n.903_904insCGCGTGA
c.451_452insCGCGTGA (p.Lys151ThrfsTer?)
c.529_530insCGCGTGA (p.Lys177ThrfsTer?)
c.640_641insCGCGTGA (p.Lys214ThrfsTer?)
c.554_555insCGCGTGA (p.Glu185AspfsTer3)
19g.1106428T>ACA402939935GPX4c.641T>A (p.Val214Glu)
c.510T>A (p.Gly170=)
c.524T>A (p.Val175Glu)
c.146T>A (p.Val49Glu)
c.530T>A (p.Val177Glu)
c.505T>A (p.Ter169Arg)
c.263T>A (p.Val88Glu)
c.410T>A (p.Val137Glu)
c.471T>A (p.Gly157=)
n.901T>A
c.449T>A (p.Val150Glu)
c.527T>A (p.Val176Glu)
c.638T>A (p.Val213Glu)
c.552T>A (p.Gly184=)
19g.1106428T>CCA402939937GPX4c.641T>C (p.Val214Ala)
c.510T>C (p.Gly170=)
c.524T>C (p.Val175Ala)
c.146T>C (p.Val49Ala)
c.530T>C (p.Val177Ala)
c.505T>C (p.Ter169Arg)
c.263T>C (p.Val88Ala)
c.410T>C (p.Val137Ala)
c.471T>C (p.Gly157=)
n.901T>C
c.449T>C (p.Val150Ala)
c.527T>C (p.Val176Ala)
c.638T>C (p.Val213Ala)
c.552T>C (p.Gly184=)
 dbSNP
19g.1106428T>GCA402939941GPX4c.641T>G (p.Val214Gly)
c.510T>G (p.Gly170=)
c.524T>G (p.Val175Gly)
c.146T>G (p.Val49Gly)
c.530T>G (p.Val177Gly)
c.505T>G (p.Ter169Gly)
c.263T>G (p.Val88Gly)
c.410T>G (p.Val137Gly)
c.471T>G (p.Gly157=)
n.901T>G
c.449T>G (p.Val150Gly)
c.527T>G (p.Val176Gly)
c.638T>G (p.Val213Gly)
c.552T>G (p.Gly184=)
19g.1106428T=CA402939944GPX4c.641T= (p.Val214=)
c.510T= (p.Gly170=)
c.524T= (p.Val175=)
c.146T= (p.Val49=)
c.530T= (p.Val177=)
c.505T= (p.Ter169=)
c.263T= (p.Val88=)
c.410T= (p.Val137=)
c.471T= (p.Gly157=)
n.901T=
c.449T= (p.Val150=)
c.527T= (p.Val176=)
c.638T= (p.Val213=)
c.552T= (p.Gly184=)
19g.1106429G>ACA402939947GPX4c.642G>A (p.Val214=)
c.511G>A (p.Glu171Lys)
c.525G>A (p.Val175=)
c.147G>A (p.Val49=)
c.531G>A (p.Val177=)
c.506G>A (p.Ter169=)
c.264G>A (p.Val88=)
c.411G>A (p.Val137=)
c.472G>A (p.Glu158Lys)
n.902G>A
c.450G>A (p.Val150=)
c.528G>A (p.Val176=)
c.639G>A (p.Val213=)
c.553G>A (p.Glu185Lys)
 ClinVar dbSNP gnomAD v2 gnomAD v4
19g.1106429G>CCA402939954GPX4c.642G>C (p.Val214=)
c.511G>C (p.Glu171Gln)
c.525G>C (p.Val175=)
c.147G>C (p.Val49=)
c.531G>C (p.Val177=)
c.506G>C (p.Ter169Ser)
c.264G>C (p.Val88=)
c.411G>C (p.Val137=)
c.472G>C (p.Glu158Gln)
n.902G>C
c.450G>C (p.Val150=)
c.528G>C (p.Val176=)
c.639G>C (p.Val213=)
c.553G>C (p.Glu185Gln)
19g.1106429G=CA402939951GPX4c.642G= (p.Val214=)
c.511G= (p.Glu171=)
c.525G= (p.Val175=)
c.147G= (p.Val49=)
c.531G= (p.Val177=)
c.506G= (p.Ter169=)
c.264G= (p.Val88=)
c.411G= (p.Val137=)
c.472G= (p.Glu158=)
n.902G=
c.450G= (p.Val150=)
c.528G= (p.Val176=)
c.639G= (p.Val213=)
c.553G= (p.Glu185=)
19g.1106429G>TCA402939949GPX4c.642G>T (p.Val214=)
c.511G>T (p.Glu171Ter)
c.525G>T (p.Val175=)
c.147G>T (p.Val49=)
c.531G>T (p.Val177=)
c.506G>T (p.Ter169Leu)
c.264G>T (p.Val88=)
c.411G>T (p.Val137=)
c.472G>T (p.Glu158Ter)
n.902G>T
c.450G>T (p.Val150=)
c.528G>T (p.Val176=)
c.639G>T (p.Val213=)
c.553G>T (p.Glu185Ter)
 dbSNP gnomAD v3 gnomAD v4
19g.1106430A=CA402939956GPX4c.643A= (p.Lys215=)
c.512A= (p.Glu171=)
c.526A= (p.Lys176=)
c.148A= (p.Lys50=)
c.532A= (p.Lys178=)
c.507A= (p.Ter169=)
c.265A= (p.Lys89=)
c.412A= (p.Lys138=)
c.473A= (p.Glu158=)
n.903A=
c.451A= (p.Lys151=)
c.529A= (p.Lys177=)
c.640A= (p.Lys214=)
c.554A= (p.Glu185=)
19g.1106430A>CCA402939960GPX4c.643A>C (p.Lys215Gln)
c.512A>C (p.Glu171Ala)
c.526A>C (p.Lys176Gln)
c.148A>C (p.Lys50Gln)
c.532A>C (p.Lys178Gln)
c.507A>C (p.Ter169Cys)
c.265A>C (p.Lys89Gln)
c.412A>C (p.Lys138Gln)
c.473A>C (p.Glu158Ala)
n.903A>C
c.451A>C (p.Lys151Gln)
c.529A>C (p.Lys177Gln)
c.640A>C (p.Lys214Gln)
c.554A>C (p.Glu185Ala)
19g.1106430A>GCA402939962GPX4c.643A>G (p.Lys215Glu)
c.512A>G (p.Glu171Gly)
c.526A>G (p.Lys176Glu)
c.148A>G (p.Lys50Glu)
c.532A>G (p.Lys178Glu)
c.507A>G (p.Ter169Trp)
c.265A>G (p.Lys89Glu)
c.412A>G (p.Lys138Glu)
c.473A>G (p.Glu158Gly)
n.903A>G
c.451A>G (p.Lys151Glu)
c.529A>G (p.Lys177Glu)
c.640A>G (p.Lys214Glu)
c.554A>G (p.Glu185Gly)
19g.1106430A>TCA402939966GPX4c.643A>T (p.Lys215Ter)
c.512A>T (p.Glu171Val)
c.526A>T (p.Lys176Ter)
c.148A>T (p.Lys50Ter)
c.532A>T (p.Lys178Ter)
c.507A>T (p.Ter169Cys)
c.265A>T (p.Lys89Ter)
c.412A>T (p.Lys138Ter)
c.473A>T (p.Glu158Val)
n.903A>T
c.451A>T (p.Lys151Ter)
c.529A>T (p.Lys177Ter)
c.640A>T (p.Lys214Ter)
c.554A>T (p.Glu185Val)
19g.1106431A=CA2317520658GPX4c.644A= (p.Lys215=)
c.513A= (p.Glu171=)
c.527A= (p.Lys176=)
c.149A= (p.Lys50=)
c.533A= (p.Lys178=)
c.508A= (p.Ser170=)
c.266A= (p.Lys89=)
c.413A= (p.Lys138=)
c.474A= (p.Glu158=)
n.904A=
c.452A= (p.Lys151=)
c.530A= (p.Lys177=)
c.641A= (p.Lys214=)
c.555A= (p.Glu185=)
19g.1106431A>CCA402939968GPX4c.644A>C (p.Lys215Thr)
c.513A>C (p.Glu171Asp)
c.527A>C (p.Lys176Thr)
c.149A>C (p.Lys50Thr)
c.533A>C (p.Lys178Thr)
c.508A>C (p.Ser170Arg)
c.266A>C (p.Lys89Thr)
c.413A>C (p.Lys138Thr)
c.474A>C (p.Glu158Asp)
n.904A>C
c.452A>C (p.Lys151Thr)
c.530A>C (p.Lys177Thr)
c.641A>C (p.Lys214Thr)
c.555A>C (p.Glu185Asp)
19g.1106431A>GCA402939984GPX4c.644A>G (p.Lys215Arg)
c.513A>G (p.Glu171=)
c.527A>G (p.Lys176Arg)
c.149A>G (p.Lys50Arg)
c.533A>G (p.Lys178Arg)
c.508A>G (p.Ser170Gly)
c.266A>G (p.Lys89Arg)
c.413A>G (p.Lys138Arg)
c.474A>G (p.Glu158=)
n.904A>G
c.452A>G (p.Lys151Arg)
c.530A>G (p.Lys177Arg)
c.641A>G (p.Lys214Arg)
c.555A>G (p.Glu185=)
 dbSNP gnomAD v3 gnomAD v4
19g.1106431A>TCA402939987GPX4c.644A>T (p.Lys215Met)
c.513A>T (p.Glu171Asp)
c.527A>T (p.Lys176Met)
c.149A>T (p.Lys50Met)
c.533A>T (p.Lys178Met)
c.508A>T (p.Ser170Cys)
c.266A>T (p.Lys89Met)
c.413A>T (p.Lys138Met)
c.474A>T (p.Glu158Asp)
n.904A>T
c.452A>T (p.Lys151Met)
c.530A>T (p.Lys177Met)
c.641A>T (p.Lys214Met)
c.555A>T (p.Glu185Asp)
 gnomAD v4
19g.1106432_1106441dupCA2576545170GPX4c.645_654dup (p.Pro219AlafsTer?)
c.514_523dup (p.Thr175SerfsTer11)
c.528_537dup (p.Pro180AlafsTer?)
c.150_159dup (p.Pro54AlafsTer?)
c.534_543dup (p.Pro182AlafsTer?)
c.509_518dup (p.Asp173GlufsTer21)
c.267_276dup (p.Pro93AlafsTer32)
c.414_423dup (p.Pro142AlafsTer?)
c.475_484dup (p.Thr162SerfsTer11)
n.905_914dup
c.514_523dup (p.Thr175SerfsTer?)
c.453_462dup (p.Pro155AlafsTer?)
c.531_540dup (p.Pro181AlafsTer?)
c.642_651dup (p.Pro218AlafsTer?)
c.556_565dup (p.Thr189SerfsTer11)
19g.1106432G>ACA402939993GPX4c.645G>A (p.Lys215=)
c.514G>A (p.Ala172Thr)
c.528G>A (p.Lys176=)
c.150G>A (p.Lys50=)
c.534G>A (p.Lys178=)
c.509G>A (p.Ser170Asn)
c.267G>A (p.Lys89=)
c.414G>A (p.Lys138=)
c.475G>A (p.Ala159Thr)
n.905G>A
c.453G>A (p.Lys151=)
c.531G>A (p.Lys177=)
c.642G>A (p.Lys214=)
c.556G>A (p.Ala186Thr)
 dbSNP gnomAD v3 gnomAD v4
19g.1106432G>CCA402939996GPX4c.645G>C (p.Lys215Asn)
c.514G>C (p.Ala172Pro)
c.528G>C (p.Lys176Asn)
c.150G>C (p.Lys50Asn)
c.534G>C (p.Lys178Asn)
c.509G>C (p.Ser170Thr)
c.267G>C (p.Lys89Asn)
c.414G>C (p.Lys138Asn)
c.475G>C (p.Ala159Pro)
n.905G>C
c.453G>C (p.Lys151Asn)
c.531G>C (p.Lys177Asn)
c.642G>C (p.Lys214Asn)
c.556G>C (p.Ala186Pro)
 dbSNP gnomAD v2 gnomAD v4
19g.1106432G=CA2317520659GPX4c.645G= (p.Lys215=)
c.514G= (p.Ala172=)
c.528G= (p.Lys176=)
c.150G= (p.Lys50=)
c.534G= (p.Lys178=)
c.509G= (p.Ser170=)
c.267G= (p.Lys89=)
c.414G= (p.Lys138=)
c.475G= (p.Ala159=)
n.905G=
c.453G= (p.Lys151=)
c.531G= (p.Lys177=)
c.642G= (p.Lys214=)
c.556G= (p.Ala186=)
19g.1106432G>TCA402939999GPX4c.645G>T (p.Lys215Asn)
c.514G>T (p.Ala172Ser)
c.528G>T (p.Lys176Asn)
c.150G>T (p.Lys50Asn)
c.534G>T (p.Lys178Asn)
c.509G>T (p.Ser170Ile)
c.267G>T (p.Lys89Asn)
c.414G>T (p.Lys138Asn)
c.475G>T (p.Ala159Ser)
n.905G>T
c.453G>T (p.Lys151Asn)
c.531G>T (p.Lys177Asn)
c.642G>T (p.Lys214Asn)
c.556G>T (p.Ala186Ser)
 gnomAD v4
19g.1106433C>ACA402940007GPX4c.646C>A (p.Arg216Ser)
c.515C>A (p.Ala172Glu)
c.529C>A (p.Arg177Ser)
c.151C>A (p.Arg51Ser)
c.535C>A (p.Arg179Ser)
c.510C>A (p.Ser170Arg)
c.268C>A (p.Arg90Ser)
c.415C>A (p.Arg139Ser)
c.476C>A (p.Ala159Glu)
n.906C>A
c.454C>A (p.Arg152Ser)
c.532C>A (p.Arg178Ser)
c.643C>A (p.Arg215Ser)
c.557C>A (p.Ala186Glu)
19g.1106433C=CA2317520660GPX4c.646C= (p.Arg216=)
c.515C= (p.Ala172=)
c.529C= (p.Arg177=)
c.151C= (p.Arg51=)
c.535C= (p.Arg179=)
c.510C= (p.Ser170=)
c.268C= (p.Arg90=)
c.415C= (p.Arg139=)
c.476C= (p.Ala159=)
n.906C=
c.454C= (p.Arg152=)
c.532C= (p.Arg178=)
c.643C= (p.Arg215=)
c.557C= (p.Ala186=)
19g.1106433C>GCA402940010GPX4c.646C>G (p.Arg216Gly)
c.515C>G (p.Ala172Gly)
c.529C>G (p.Arg177Gly)
c.151C>G (p.Arg51Gly)
c.535C>G (p.Arg179Gly)
c.510C>G (p.Ser170Arg)
c.268C>G (p.Arg90Gly)
c.415C>G (p.Arg139Gly)
c.476C>G (p.Ala159Gly)
n.906C>G
c.454C>G (p.Arg152Gly)
c.532C>G (p.Arg178Gly)
c.643C>G (p.Arg215Gly)
c.557C>G (p.Ala186Gly)
19g.1106433C>TCA9037476GPX4c.646C>T (p.Arg216Cys)
c.515C>T (p.Ala172Val)
c.529C>T (p.Arg177Cys)
c.151C>T (p.Arg51Cys)
c.535C>T (p.Arg179Cys)
c.510C>T (p.Ser170=)
c.268C>T (p.Arg90Cys)
c.415C>T (p.Arg139Cys)
c.476C>T (p.Ala159Val)
n.906C>T
c.454C>T (p.Arg152Cys)
c.532C>T (p.Arg178Cys)
c.643C>T (p.Arg215Cys)
c.557C>T (p.Ala186Val)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106434G>ACA9037477GPX4c.647G>A (p.Arg216His)
c.516G>A (p.Ala172=)
c.530G>A (p.Arg177His)
c.152G>A (p.Arg51His)
c.536G>A (p.Arg179His)
c.511G>A (p.Ala171Thr)
c.269G>A (p.Arg90His)
c.416G>A (p.Arg139His)
c.477G>A (p.Ala159=)
n.907G>A
c.455G>A (p.Arg152His)
c.533G>A (p.Arg178His)
c.644G>A (p.Arg215His)
c.558G>A (p.Ala186=)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106434G>CCA402940012GPX4c.647G>C (p.Arg216Pro)
c.516G>C (p.Ala172=)
c.530G>C (p.Arg177Pro)
c.152G>C (p.Arg51Pro)
c.536G>C (p.Arg179Pro)
c.511G>C (p.Ala171Pro)
c.269G>C (p.Arg90Pro)
c.416G>C (p.Arg139Pro)
c.477G>C (p.Ala159=)
n.907G>C
c.455G>C (p.Arg152Pro)
c.533G>C (p.Arg178Pro)
c.644G>C (p.Arg215Pro)
c.558G>C (p.Ala186=)
 dbSNP
19g.1106434G=CA2317520661GPX4c.647G= (p.Arg216=)
c.516G= (p.Ala172=)
c.530G= (p.Arg177=)
c.152G= (p.Arg51=)
c.536G= (p.Arg179=)
c.511G= (p.Ala171=)
c.269G= (p.Arg90=)
c.416G= (p.Arg139=)
c.477G= (p.Ala159=)
n.907G=
c.455G= (p.Arg152=)
c.533G= (p.Arg178=)
c.644G= (p.Arg215=)
c.558G= (p.Ala186=)
19g.1106434G>TCA402940011GPX4c.647G>T (p.Arg216Leu)
c.516G>T (p.Ala172=)
c.530G>T (p.Arg177Leu)
c.152G>T (p.Arg51Leu)
c.536G>T (p.Arg179Leu)
c.511G>T (p.Ala171Ser)
c.269G>T (p.Arg90Leu)
c.416G>T (p.Arg139Leu)
c.477G>T (p.Ala159=)
n.907G>T
c.455G>T (p.Arg152Leu)
c.533G>T (p.Arg178Leu)
c.644G>T (p.Arg215Leu)
c.558G>T (p.Ala186=)
19g.1106435C>ACA402940015GPX4c.648C>A (p.Arg216=)
c.517C>A (p.Leu173Ile)
c.531C>A (p.Arg177=)
c.153C>A (p.Arg51=)
c.537C>A (p.Arg179=)
c.512C>A (p.Ala171Asp)
c.270C>A (p.Arg90=)
c.417C>A (p.Arg139=)
c.478C>A (p.Leu160Ile)
n.908C>A
c.456C>A (p.Arg152=)
c.534C>A (p.Arg178=)
c.645C>A (p.Arg215=)
c.559C>A (p.Leu187Ile)
19g.1106435C>GCA402940019GPX4c.648C>G (p.Arg216=)
c.517C>G (p.Leu173Val)
c.531C>G (p.Arg177=)
c.153C>G (p.Arg51=)
c.537C>G (p.Arg179=)
c.512C>G (p.Ala171Gly)
c.270C>G (p.Arg90=)
c.417C>G (p.Arg139=)
c.478C>G (p.Leu160Val)
n.908C>G
c.456C>G (p.Arg152=)
c.534C>G (p.Arg178=)
c.645C>G (p.Arg215=)
c.559C>G (p.Leu187Val)
19g.1106435C>TCA402940017GPX4c.648C>T (p.Arg216=)
c.517C>T (p.Leu173=)
c.531C>T (p.Arg177=)
c.153C>T (p.Arg51=)
c.537C>T (p.Arg179=)
c.512C>T (p.Ala171Val)
c.270C>T (p.Arg90=)
c.417C>T (p.Arg139=)
c.478C>T (p.Leu160=)
n.908C>T
c.456C>T (p.Arg152=)
c.534C>T (p.Arg178=)
c.645C>T (p.Arg215=)
c.559C>T (p.Leu187=)
19g.1106436T>ACA402940022GPX4c.649T>A (p.Tyr217Asn)
c.518T>A (p.Leu173Gln)
c.532T>A (p.Tyr178Asn)
c.154T>A (p.Tyr52Asn)
c.538T>A (p.Tyr180Asn)
c.513T>A (p.Ala171=)
c.271T>A (p.Tyr91Asn)
c.418T>A (p.Tyr140Asn)
c.479T>A (p.Leu160Gln)
n.909T>A
c.457T>A (p.Tyr153Asn)
c.535T>A (p.Tyr179Asn)
c.646T>A (p.Tyr216Asn)
c.560T>A (p.Leu187Gln)
19g.1106436T>CCA402940025GPX4c.649T>C (p.Tyr217His)
c.518T>C (p.Leu173Pro)
c.532T>C (p.Tyr178His)
c.154T>C (p.Tyr52His)
c.538T>C (p.Tyr180His)
c.513T>C (p.Ala171=)
c.271T>C (p.Tyr91His)
c.418T>C (p.Tyr140His)
c.479T>C (p.Leu160Pro)
n.909T>C
c.457T>C (p.Tyr153His)
c.535T>C (p.Tyr179His)
c.646T>C (p.Tyr216His)
c.560T>C (p.Leu187Pro)
 gnomAD v4
19g.1106436T>GCA402940029GPX4c.649T>G (p.Tyr217Asp)
c.518T>G (p.Leu173Arg)
c.532T>G (p.Tyr178Asp)
c.154T>G (p.Tyr52Asp)
c.538T>G (p.Tyr180Asp)
c.513T>G (p.Ala171=)
c.271T>G (p.Tyr91Asp)
c.418T>G (p.Tyr140Asp)
c.479T>G (p.Leu160Arg)
n.909T>G
c.457T>G (p.Tyr153Asp)
c.535T>G (p.Tyr179Asp)
c.646T>G (p.Tyr216Asp)
c.560T>G (p.Leu187Arg)
19g.1106437A=CA2317520662GPX4c.650A= (p.Tyr217=)
c.519A= (p.Leu173=)
c.533A= (p.Tyr178=)
c.155A= (p.Tyr52=)
c.539A= (p.Tyr180=)
c.514A= (p.Thr172=)
c.272A= (p.Tyr91=)
c.419A= (p.Tyr140=)
c.480A= (p.Leu160=)
n.910A=
c.458A= (p.Tyr153=)
c.536A= (p.Tyr179=)
c.647A= (p.Tyr216=)
c.561A= (p.Leu187=)
19g.1106437A>CCA402940034GPX4c.650A>C (p.Tyr217Ser)
c.519A>C (p.Leu173=)
c.533A>C (p.Tyr178Ser)
c.155A>C (p.Tyr52Ser)
c.539A>C (p.Tyr180Ser)
c.514A>C (p.Thr172Pro)
c.272A>C (p.Tyr91Ser)
c.419A>C (p.Tyr140Ser)
c.480A>C (p.Leu160=)
n.910A>C
c.458A>C (p.Tyr153Ser)
c.536A>C (p.Tyr179Ser)
c.647A>C (p.Tyr216Ser)
c.561A>C (p.Leu187=)
19g.1106437A>GCA402940037GPX4c.650A>G (p.Tyr217Cys)
c.519A>G (p.Leu173=)
c.533A>G (p.Tyr178Cys)
c.155A>G (p.Tyr52Cys)
c.539A>G (p.Tyr180Cys)
c.514A>G (p.Thr172Ala)
c.272A>G (p.Tyr91Cys)
c.419A>G (p.Tyr140Cys)
c.480A>G (p.Leu160=)
n.910A>G
c.458A>G (p.Tyr153Cys)
c.536A>G (p.Tyr179Cys)
c.647A>G (p.Tyr216Cys)
c.561A>G (p.Leu187=)
 dbSNP gnomAD v2 gnomAD v4
19g.1106437A>TCA402940040GPX4c.650A>T (p.Tyr217Phe)
c.519A>T (p.Leu173=)
c.533A>T (p.Tyr178Phe)
c.155A>T (p.Tyr52Phe)
c.539A>T (p.Tyr180Phe)
c.514A>T (p.Thr172Ser)
c.272A>T (p.Tyr91Phe)
c.419A>T (p.Tyr140Phe)
c.480A>T (p.Leu160=)
n.910A>T
c.458A>T (p.Tyr153Phe)
c.536A>T (p.Tyr179Phe)
c.647A>T (p.Tyr216Phe)
c.561A>T (p.Leu187=)
19g.1106438C>ACA402940042GPX4c.651C>A (p.Tyr217Ter)
c.520C>A (p.Arg174=)
c.534C>A (p.Tyr178Ter)
c.156C>A (p.Tyr52Ter)
c.540C>A (p.Tyr180Ter)
c.515C>A (p.Thr172Lys)
c.273C>A (p.Tyr91Ter)
c.420C>A (p.Tyr140Ter)
c.481C>A (p.Arg161=)
n.911C>A
c.459C>A (p.Tyr153Ter)
c.537C>A (p.Tyr179Ter)
c.648C>A (p.Tyr216Ter)
c.562C>A (p.Arg188=)
19g.1106438C=CA2317520663GPX4c.651C= (p.Tyr217=)
c.520C= (p.Arg174=)
c.534C= (p.Tyr178=)
c.156C= (p.Tyr52=)
c.540C= (p.Tyr180=)
c.515C= (p.Thr172=)
c.273C= (p.Tyr91=)
c.420C= (p.Tyr140=)
c.481C= (p.Arg161=)
n.911C=
c.459C= (p.Tyr153=)
c.537C= (p.Tyr179=)
c.648C= (p.Tyr216=)
c.562C= (p.Arg188=)
19g.1106438C>GCA9037479GPX4c.651C>G (p.Tyr217Ter)
c.520C>G (p.Arg174Gly)
c.534C>G (p.Tyr178Ter)
c.156C>G (p.Tyr52Ter)
c.540C>G (p.Tyr180Ter)
c.515C>G (p.Thr172Arg)
c.273C>G (p.Tyr91Ter)
c.420C>G (p.Tyr140Ter)
c.481C>G (p.Arg161Gly)
n.911C>G
c.459C>G (p.Tyr153Ter)
c.537C>G (p.Tyr179Ter)
c.648C>G (p.Tyr216Ter)
c.562C>G (p.Arg188Gly)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106438C>TCA9037478GPX4c.651C>T (p.Tyr217=)
c.520C>T (p.Arg174Trp)
c.534C>T (p.Tyr178=)
c.156C>T (p.Tyr52=)
c.540C>T (p.Tyr180=)
c.515C>T (p.Thr172Met)
c.273C>T (p.Tyr91=)
c.420C>T (p.Tyr140=)
c.481C>T (p.Arg161Trp)
n.911C>T
c.459C>T (p.Tyr153=)
c.537C>T (p.Tyr179=)
c.648C>T (p.Tyr216=)
c.562C>T (p.Arg188Trp)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106439G>ACA9037480GPX4c.652G>A (p.Gly218Arg)
c.521G>A (p.Arg174Gln)
c.535G>A (p.Gly179Arg)
c.157G>A (p.Gly53Arg)
c.541G>A (p.Gly181Arg)
c.516G>A (p.Thr172=)
c.274G>A (p.Gly92Arg)
c.421G>A (p.Gly141Arg)
c.482G>A (p.Arg161Gln)
n.912G>A
c.460G>A (p.Gly154Arg)
c.538G>A (p.Gly180Arg)
c.649G>A (p.Gly217Arg)
c.563G>A (p.Arg188Gln)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106439G>CCA402940055GPX4c.652G>C (p.Gly218Arg)
c.521G>C (p.Arg174Pro)
c.535G>C (p.Gly179Arg)
c.157G>C (p.Gly53Arg)
c.541G>C (p.Gly181Arg)
c.516G>C (p.Thr172=)
c.274G>C (p.Gly92Arg)
c.421G>C (p.Gly141Arg)
c.482G>C (p.Arg161Pro)
n.912G>C
c.460G>C (p.Gly154Arg)
c.538G>C (p.Gly180Arg)
c.649G>C (p.Gly217Arg)
c.563G>C (p.Arg188Pro)
19g.1106439G=CA2317520664GPX4c.652G= (p.Gly218=)
c.521G= (p.Arg174=)
c.535G= (p.Gly179=)
c.157G= (p.Gly53=)
c.541G= (p.Gly181=)
c.516G= (p.Thr172=)
c.274G= (p.Gly92=)
c.421G= (p.Gly141=)
c.482G= (p.Arg161=)
n.912G=
c.460G= (p.Gly154=)
c.538G= (p.Gly180=)
c.649G= (p.Gly217=)
c.563G= (p.Arg188=)
19g.1106439G>TCA402940058GPX4c.652G>T (p.Gly218Ter)
c.521G>T (p.Arg174Leu)
c.535G>T (p.Gly179Ter)
c.157G>T (p.Gly53Ter)
c.541G>T (p.Gly181Ter)
c.516G>T (p.Thr172=)
c.274G>T (p.Gly92Ter)
c.421G>T (p.Gly141Ter)
c.482G>T (p.Arg161Leu)
n.912G>T
c.460G>T (p.Gly154Ter)
c.538G>T (p.Gly180Ter)
c.649G>T (p.Gly217Ter)
c.563G>T (p.Arg188Leu)
19g.1106439_1106440delinsAACA645603782GPX4c.652_653delinsAA (p.Gly218Lys)
c.521_522delinsAA (p.Arg174Gln)
c.535_536delinsAA (p.Gly179Lys)
c.157_158delinsAA (p.Gly53Lys)
c.541_542delinsAA (p.Gly181Lys)
c.516_517delinsAA (p.Asp173Asn)
c.274_275delinsAA (p.Gly92Lys)
c.421_422delinsAA (p.Gly141Lys)
c.482_483delinsAA (p.Arg161Gln)
n.912_913delinsAA
c.460_461delinsAA (p.Gly154Lys)
c.538_539delinsAA (p.Gly180Lys)
c.649_650delinsAA (p.Gly217Lys)
c.563_564delinsAA (p.Arg188Gln)
 COSMIC
19g.1106440G>ACA402940064GPX4c.653G>A (p.Gly218Glu)
c.522G>A (p.Arg174=)
c.536G>A (p.Gly179Glu)
c.158G>A (p.Gly53Glu)
c.542G>A (p.Gly181Glu)
c.517G>A (p.Asp173Asn)
c.275G>A (p.Gly92Glu)
c.422G>A (p.Gly141Glu)
c.483G>A (p.Arg161=)
n.913G>A
c.461G>A (p.Gly154Glu)
c.539G>A (p.Gly180Glu)
c.650G>A (p.Gly217Glu)
c.564G>A (p.Arg188=)
 gnomAD v4
19g.1106440G>CCA402940068GPX4c.653G>C (p.Gly218Ala)
c.522G>C (p.Arg174=)
c.536G>C (p.Gly179Ala)
c.158G>C (p.Gly53Ala)
c.542G>C (p.Gly181Ala)
c.517G>C (p.Asp173His)
c.275G>C (p.Gly92Ala)
c.422G>C (p.Gly141Ala)
c.483G>C (p.Arg161=)
n.913G>C
c.461G>C (p.Gly154Ala)
c.539G>C (p.Gly180Ala)
c.650G>C (p.Gly217Ala)
c.564G>C (p.Arg188=)
 dbSNP gnomAD v2 gnomAD v4
19g.1106440G=CA2317520665GPX4c.653G= (p.Gly218=)
c.522G= (p.Arg174=)
c.536G= (p.Gly179=)
c.158G= (p.Gly53=)
c.542G= (p.Gly181=)
c.517G= (p.Asp173=)
c.275G= (p.Gly92=)
c.422G= (p.Gly141=)
c.483G= (p.Arg161=)
n.913G=
c.461G= (p.Gly154=)
c.539G= (p.Gly180=)
c.650G= (p.Gly217=)
c.564G= (p.Arg188=)
19g.1106440G>TCA402940067GPX4c.653G>T (p.Gly218Val)
c.522G>T (p.Arg174=)
c.536G>T (p.Gly179Val)
c.158G>T (p.Gly53Val)
c.542G>T (p.Gly181Val)
c.517G>T (p.Asp173Tyr)
c.275G>T (p.Gly92Val)
c.422G>T (p.Gly141Val)
c.483G>T (p.Arg161=)
n.913G>T
c.461G>T (p.Gly154Val)
c.539G>T (p.Gly180Val)
c.650G>T (p.Gly217Val)
c.564G>T (p.Arg188=)
19g.1106441A=CA2317520666GPX4c.654A= (p.Gly218=)
c.523A= (p.Thr175=)
c.537A= (p.Gly179=)
c.159A= (p.Gly53=)
c.543A= (p.Gly181=)
c.518A= (p.Asp173=)
c.276A= (p.Gly92=)
c.423A= (p.Gly141=)
c.484A= (p.Thr162=)
n.914A=
c.462A= (p.Gly154=)
c.540A= (p.Gly180=)
c.651A= (p.Gly217=)
c.565A= (p.Thr189=)
19g.1106441A>CCA402940069GPX4c.654A>C (p.Gly218=)
c.523A>C (p.Thr175Pro)
c.537A>C (p.Gly179=)
c.159A>C (p.Gly53=)
c.543A>C (p.Gly181=)
c.518A>C (p.Asp173Ala)
c.276A>C (p.Gly92=)
c.423A>C (p.Gly141=)
c.484A>C (p.Thr162Pro)
n.914A>C
c.462A>C (p.Gly154=)
c.540A>C (p.Gly180=)
c.651A>C (p.Gly217=)
c.565A>C (p.Thr189Pro)
19g.1106441A>GCA402940071GPX4c.654A>G (p.Gly218=)
c.523A>G (p.Thr175Ala)
c.537A>G (p.Gly179=)
c.159A>G (p.Gly53=)
c.543A>G (p.Gly181=)
c.518A>G (p.Asp173Gly)
c.276A>G (p.Gly92=)
c.423A>G (p.Gly141=)
c.484A>G (p.Thr162Ala)
n.914A>G
c.462A>G (p.Gly154=)
c.540A>G (p.Gly180=)
c.651A>G (p.Gly217=)
c.565A>G (p.Thr189Ala)
19g.1106441A>TCA402940074GPX4c.654A>T (p.Gly218=)
c.523A>T (p.Thr175Ser)
c.537A>T (p.Gly179=)
c.159A>T (p.Gly53=)
c.543A>T (p.Gly181=)
c.518A>T (p.Asp173Val)
c.276A>T (p.Gly92=)
c.423A>T (p.Gly141=)
c.484A>T (p.Thr162Ser)
n.914A>T
c.462A>T (p.Gly154=)
c.540A>T (p.Gly180=)
c.651A>T (p.Gly217=)
c.565A>T (p.Thr189Ser)
 dbSNP
19g.1106442C>ACA402940078GPX4c.655C>A (p.Pro219Thr)
c.524C>A (p.Thr175Asn)
c.538C>A (p.Pro180Thr)
c.160C>A (p.Pro54Thr)
c.544C>A (p.Pro182Thr)
c.519C>A (p.Asp173Glu)
c.277C>A (p.Pro93Thr)
c.424C>A (p.Pro142Thr)
c.485C>A (p.Thr162Asn)
n.915C>A
c.463C>A (p.Pro155Thr)
c.541C>A (p.Pro181Thr)
c.652C>A (p.Pro218Thr)
c.566C>A (p.Thr189Asn)
19g.1106442C=CA2317520667GPX4c.655C= (p.Pro219=)
c.524C= (p.Thr175=)
c.538C= (p.Pro180=)
c.160C= (p.Pro54=)
c.544C= (p.Pro182=)
c.519C= (p.Asp173=)
c.277C= (p.Pro93=)
c.424C= (p.Pro142=)
c.485C= (p.Thr162=)
n.915C=
c.463C= (p.Pro155=)
c.541C= (p.Pro181=)
c.652C= (p.Pro218=)
c.566C= (p.Thr189=)
19g.1106442C>GCA402940080GPX4c.655C>G (p.Pro219Ala)
c.524C>G (p.Thr175Ser)
c.538C>G (p.Pro180Ala)
c.160C>G (p.Pro54Ala)
c.544C>G (p.Pro182Ala)
c.519C>G (p.Asp173Glu)
c.277C>G (p.Pro93Ala)
c.424C>G (p.Pro142Ala)
c.485C>G (p.Thr162Ser)
n.915C>G
c.463C>G (p.Pro155Ala)
c.541C>G (p.Pro181Ala)
c.652C>G (p.Pro218Ala)
c.566C>G (p.Thr189Ser)
19g.1106442C>TCA9037481GPX4c.655C>T (p.Pro219Ser)
c.524C>T (p.Thr175Ile)
c.538C>T (p.Pro180Ser)
c.160C>T (p.Pro54Ser)
c.544C>T (p.Pro182Ser)
c.519C>T (p.Asp173=)
c.277C>T (p.Pro93Ser)
c.424C>T (p.Pro142Ser)
c.485C>T (p.Thr162Ile)
n.915C>T
c.463C>T (p.Pro155Ser)
c.541C>T (p.Pro181Ser)
c.652C>T (p.Pro218Ser)
c.566C>T (p.Thr189Ile)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106443C>ACA402940085GPX4c.656C>A (p.Pro219His)
c.525C>A (p.Thr175=)
c.539C>A (p.Pro180His)
c.161C>A (p.Pro54His)
c.545C>A (p.Pro182His)
c.520C>A (p.Pro174Thr)
c.278C>A (p.Pro93His)
c.425C>A (p.Pro142His)
c.486C>A (p.Thr162=)
n.916C>A
c.464C>A (p.Pro155His)
c.542C>A (p.Pro181His)
c.653C>A (p.Pro218His)
c.567C>A (p.Thr189=)
19g.1106443C>GCA402940086GPX4c.656C>G (p.Pro219Arg)
c.525C>G (p.Thr175=)
c.539C>G (p.Pro180Arg)
c.161C>G (p.Pro54Arg)
c.545C>G (p.Pro182Arg)
c.520C>G (p.Pro174Ala)
c.278C>G (p.Pro93Arg)
c.425C>G (p.Pro142Arg)
c.486C>G (p.Thr162=)
n.916C>G
c.464C>G (p.Pro155Arg)
c.542C>G (p.Pro181Arg)
c.653C>G (p.Pro218Arg)
c.567C>G (p.Thr189=)
19g.1106443C>TCA402940088GPX4c.656C>T (p.Pro219Leu)
c.525C>T (p.Thr175=)
c.539C>T (p.Pro180Leu)
c.161C>T (p.Pro54Leu)
c.545C>T (p.Pro182Leu)
c.520C>T (p.Pro174Ser)
c.278C>T (p.Pro93Leu)
c.425C>T (p.Pro142Leu)
c.486C>T (p.Thr162=)
n.916C>T
c.464C>T (p.Pro155Leu)
c.542C>T (p.Pro181Leu)
c.653C>T (p.Pro218Leu)
c.567C>T (p.Thr189=)
 ClinVar
19g.1106444C>ACA402940092GPX4c.657C>A (p.Pro219=)
c.526C>A (p.His176Asn)
c.540C>A (p.Pro180=)
c.162C>A (p.Pro54=)
c.546C>A (p.Pro182=)
c.521C>A (p.Pro174Gln)
c.279C>A (p.Pro93=)
c.426C>A (p.Pro142=)
c.487C>A (p.His163Asn)
n.917C>A
c.465C>A (p.Pro155=)
c.543C>A (p.Pro181=)
c.654C>A (p.Pro218=)
c.568C>A (p.His190Asn)
19g.1106444C>GCA402940094GPX4c.657C>G (p.Pro219=)
c.526C>G (p.His176Asp)
c.540C>G (p.Pro180=)
c.162C>G (p.Pro54=)
c.546C>G (p.Pro182=)
c.521C>G (p.Pro174Arg)
c.279C>G (p.Pro93=)
c.426C>G (p.Pro142=)
c.487C>G (p.His163Asp)
n.917C>G
c.465C>G (p.Pro155=)
c.543C>G (p.Pro181=)
c.654C>G (p.Pro218=)
c.568C>G (p.His190Asp)
19g.1106444C>TCA402940090GPX4c.657C>T (p.Pro219=)
c.526C>T (p.His176Tyr)
c.540C>T (p.Pro180=)
c.162C>T (p.Pro54=)
c.546C>T (p.Pro182=)
c.521C>T (p.Pro174Leu)
c.279C>T (p.Pro93=)
c.426C>T (p.Pro142=)
c.487C>T (p.His163Tyr)
n.917C>T
c.465C>T (p.Pro155=)
c.543C>T (p.Pro181=)
c.654C>T (p.Pro218=)
c.568C>T (p.His190Tyr)
 gnomAD v4
19g.1106445A=CA2317520668GPX4c.658A= (p.Met220=)
c.527A= (p.His176=)
c.541A= (p.Met181=)
c.163A= (p.Met55=)
c.547A= (p.Met183=)
c.522A= (p.Pro174=)
c.280A= (p.Met94=)
c.427A= (p.Met143=)
c.488A= (p.His163=)
n.918A=
c.466A= (p.Met156=)
c.544A= (p.Met182=)
c.655A= (p.Met219=)
c.569A= (p.His190=)
19g.1106445A>CCA402940096GPX4c.658A>C (p.Met220Leu)
c.527A>C (p.His176Pro)
c.541A>C (p.Met181Leu)
c.163A>C (p.Met55Leu)
c.547A>C (p.Met183Leu)
c.522A>C (p.Pro174=)
c.280A>C (p.Met94Leu)
c.427A>C (p.Met143Leu)
c.488A>C (p.His163Pro)
n.918A>C
c.466A>C (p.Met156Leu)
c.544A>C (p.Met182Leu)
c.655A>C (p.Met219Leu)
c.569A>C (p.His190Pro)
19g.1106445A>GCA303994953GPX4c.658A>G (p.Met220Val)
c.527A>G (p.His176Arg)
c.541A>G (p.Met181Val)
c.163A>G (p.Met55Val)
c.547A>G (p.Met183Val)
c.522A>G (p.Pro174=)
c.280A>G (p.Met94Val)
c.427A>G (p.Met143Val)
c.488A>G (p.His163Arg)
n.918A>G
c.466A>G (p.Met156Val)
c.544A>G (p.Met182Val)
c.655A>G (p.Met219Val)
c.569A>G (p.His190Arg)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
19g.1106445A>TCA402940097GPX4c.658A>T (p.Met220Leu)
c.527A>T (p.His176Leu)
c.541A>T (p.Met181Leu)
c.163A>T (p.Met55Leu)
c.547A>T (p.Met183Leu)
c.522A>T (p.Pro174=)
c.280A>T (p.Met94Leu)
c.427A>T (p.Met143Leu)
c.488A>T (p.His163Leu)
n.918A>T
c.466A>T (p.Met156Leu)
c.544A>T (p.Met182Leu)
c.655A>T (p.Met219Leu)
c.569A>T (p.His190Leu)
19g.1106446T>ACA402940098GPX4c.659T>A (p.Met220Lys)
c.528T>A (p.His176Gln)
c.542T>A (p.Met181Lys)
c.164T>A (p.Met55Lys)
c.548T>A (p.Met183Lys)
c.523T>A (p.Trp175Arg)
c.281T>A (p.Met94Lys)
c.428T>A (p.Met143Lys)
c.489T>A (p.His163Gln)
n.919T>A
c.467T>A (p.Met156Lys)
c.545T>A (p.Met182Lys)
c.656T>A (p.Met219Lys)
c.570T>A (p.His190Gln)
 gnomAD v4
19g.1106446T>CCA9037482GPX4c.659T>C (p.Met220Thr)
c.528T>C (p.His176=)
c.542T>C (p.Met181Thr)
c.164T>C (p.Met55Thr)
c.548T>C (p.Met183Thr)
c.523T>C (p.Trp175Arg)
c.281T>C (p.Met94Thr)
c.428T>C (p.Met143Thr)
c.489T>C (p.His163=)
n.919T>C
c.467T>C (p.Met156Thr)
c.545T>C (p.Met182Thr)
c.656T>C (p.Met219Thr)
c.570T>C (p.His190=)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106446T>GCA402940101GPX4c.659T>G (p.Met220Arg)
c.528T>G (p.His176Gln)
c.542T>G (p.Met181Arg)
c.164T>G (p.Met55Arg)
c.548T>G (p.Met183Arg)
c.523T>G (p.Trp175Gly)
c.281T>G (p.Met94Arg)
c.428T>G (p.Met143Arg)
c.489T>G (p.His163Gln)
n.919T>G
c.467T>G (p.Met156Arg)
c.545T>G (p.Met182Arg)
c.656T>G (p.Met219Arg)
c.570T>G (p.His190Gln)
19g.1106446T=CA2317520669GPX4c.659T= (p.Met220=)
c.528T= (p.His176=)
c.542T= (p.Met181=)
c.164T= (p.Met55=)
c.548T= (p.Met183=)
c.523T= (p.Trp175=)
c.281T= (p.Met94=)
c.428T= (p.Met143=)
c.489T= (p.His163=)
n.919T=
c.467T= (p.Met156=)
c.545T= (p.Met182=)
c.656T= (p.Met219=)
c.570T= (p.His190=)
19g.1106447G>ACA402940103GPX4c.660G>A (p.Met220Ile)
c.529G>A (p.Gly177Arg)
c.543G>A (p.Met181Ile)
c.165G>A (p.Met55Ile)
c.549G>A (p.Met183Ile)
c.524G>A (p.Trp175Ter)
c.282G>A (p.Met94Ile)
c.429G>A (p.Met143Ile)
c.490G>A (p.Gly164Arg)
n.920G>A
c.468G>A (p.Met156Ile)
c.546G>A (p.Met182Ile)
c.657G>A (p.Met219Ile)
c.571G>A (p.Gly191Arg)
 dbSNP gnomAD v2 gnomAD v4
19g.1106447G>CCA402940105GPX4c.660G>C (p.Met220Ile)
c.529G>C (p.Gly177Arg)
c.543G>C (p.Met181Ile)
c.165G>C (p.Met55Ile)
c.549G>C (p.Met183Ile)
c.524G>C (p.Trp175Ser)
c.282G>C (p.Met94Ile)
c.429G>C (p.Met143Ile)
c.490G>C (p.Gly164Arg)
n.920G>C
c.468G>C (p.Met156Ile)
c.546G>C (p.Met182Ile)
c.657G>C (p.Met219Ile)
c.571G>C (p.Gly191Arg)
19g.1106447G=CA2317520670GPX4c.660G= (p.Met220=)
c.529G= (p.Gly177=)
c.543G= (p.Met181=)
c.165G= (p.Met55=)
c.549G= (p.Met183=)
c.524G= (p.Trp175=)
c.282G= (p.Met94=)
c.429G= (p.Met143=)
c.490G= (p.Gly164=)
n.920G=
c.468G= (p.Met156=)
c.546G= (p.Met182=)
c.657G= (p.Met219=)
c.571G= (p.Gly191=)
19g.1106447G>TCA402940106GPX4c.660G>T (p.Met220Ile)
c.529G>T (p.Gly177Ter)
c.543G>T (p.Met181Ile)
c.165G>T (p.Met55Ile)
c.549G>T (p.Met183Ile)
c.524G>T (p.Trp175Leu)
c.282G>T (p.Met94Ile)
c.429G>T (p.Met143Ile)
c.490G>T (p.Gly164Ter)
n.920G>T
c.468G>T (p.Met156Ile)
c.546G>T (p.Met182Ile)
c.657G>T (p.Met219Ile)
c.571G>T (p.Gly191Ter)
19g.1106448G>ACA402940107GPX4c.661G>A (p.Glu221Lys)
c.530G>A (p.Gly177Glu)
c.544G>A (p.Glu182Lys)
c.166G>A (p.Glu56Lys)
c.550G>A (p.Glu184Lys)
c.525G>A (p.Trp175Ter)
c.283G>A (p.Glu95Lys)
c.430G>A (p.Glu144Lys)
c.491G>A (p.Gly164Glu)
n.921G>A
c.469G>A (p.Glu157Lys)
c.547G>A (p.Glu183Lys)
c.658G>A (p.Glu220Lys)
c.572G>A (p.Gly191Glu)
19g.1106448G>CCA402940109GPX4c.661G>C (p.Glu221Gln)
c.530G>C (p.Gly177Ala)
c.544G>C (p.Glu182Gln)
c.166G>C (p.Glu56Gln)
c.550G>C (p.Glu184Gln)
c.525G>C (p.Trp175Cys)
c.283G>C (p.Glu95Gln)
c.430G>C (p.Glu144Gln)
c.491G>C (p.Gly164Ala)
n.921G>C
c.469G>C (p.Glu157Gln)
c.547G>C (p.Glu183Gln)
c.658G>C (p.Glu220Gln)
c.572G>C (p.Gly191Ala)
 ClinVar dbSNP gnomAD v2 gnomAD v4
19g.1106448G=CA2317520671GPX4c.661G= (p.Glu221=)
c.530G= (p.Gly177=)
c.544G= (p.Glu182=)
c.166G= (p.Glu56=)
c.550G= (p.Glu184=)
c.525G= (p.Trp175=)
c.283G= (p.Glu95=)
c.430G= (p.Glu144=)
c.491G= (p.Gly164=)
n.921G=
c.469G= (p.Glu157=)
c.547G= (p.Glu183=)
c.658G= (p.Glu220=)
c.572G= (p.Gly191=)
19g.1106448G>TCA9037483GPX4c.661G>T (p.Glu221Ter)
c.530G>T (p.Gly177Val)
c.544G>T (p.Glu182Ter)
c.166G>T (p.Glu56Ter)
c.550G>T (p.Glu184Ter)
c.525G>T (p.Trp175Cys)
c.283G>T (p.Glu95Ter)
c.430G>T (p.Glu144Ter)
c.491G>T (p.Gly164Val)
n.921G>T
c.469G>T (p.Glu157Ter)
c.547G>T (p.Glu183Ter)
c.658G>T (p.Glu220Ter)
c.572G>T (p.Gly191Val)
 dbSNP ExAC gnomAD v2 gnomAD v4
19g.1106449A>CCA402940115GPX4c.662A>C (p.Glu221Ala)
c.531A>C (p.Gly177=)
c.545A>C (p.Glu182Ala)
c.167A>C (p.Glu56Ala)
c.551A>C (p.Glu184Ala)
c.526A>C (p.Arg176=)
c.284A>C (p.Glu95Ala)
c.431A>C (p.Glu144Ala)
c.492A>C (p.Gly164=)
n.922A>C
c.470A>C (p.Glu157Ala)
c.548A>C (p.Glu183Ala)
c.659A>C (p.Glu220Ala)
c.573A>C (p.Gly191=)
19g.1106449A>GCA402940112GPX4c.662A>G (p.Glu221Gly)
c.531A>G (p.Gly177=)
c.545A>G (p.Glu182Gly)
c.167A>G (p.Glu56Gly)
c.551A>G (p.Glu184Gly)
c.526A>G (p.Arg176Gly)
c.284A>G (p.Glu95Gly)
c.431A>G (p.Glu144Gly)
c.492A>G (p.Gly164=)
n.922A>G
c.470A>G (p.Glu157Gly)
c.548A>G (p.Glu183Gly)
c.659A>G (p.Glu220Gly)
c.573A>G (p.Gly191=)
19g.1106449A>TCA402940114GPX4c.662A>T (p.Glu221Val)
c.531A>T (p.Gly177=)
c.545A>T (p.Glu182Val)
c.167A>T (p.Glu56Val)
c.551A>T (p.Glu184Val)
c.526A>T (p.Arg176Trp)
c.284A>T (p.Glu95Val)
c.431A>T (p.Glu144Val)
c.492A>T (p.Gly164=)
n.922A>T
c.470A>T (p.Glu157Val)
c.548A>T (p.Glu183Val)
c.659A>T (p.Glu220Val)
c.573A>T (p.Gly191=)
19g.1106450G>ACA402940121GPX4c.663G>A (p.Glu221=)
c.532G>A (p.Gly178Arg)
c.546G>A (p.Glu182=)
c.168G>A (p.Glu56=)
c.552G>A (p.Glu184=)
c.527G>A (p.Arg176Lys)
c.285G>A (p.Glu95=)
c.432G>A (p.Glu144=)
c.493G>A (p.Gly165Arg)
n.923G>A
c.471G>A (p.Glu157=)
c.549G>A (p.Glu183=)
c.660G>A (p.Glu220=)
c.574G>A (p.Gly192Arg)
19g.1106450G>CCA402940125GPX4c.663G>C (p.Glu221Asp)
c.532G>C (p.Gly178Arg)
c.546G>C (p.Glu182Asp)
c.168G>C (p.Glu56Asp)
c.552G>C (p.Glu184Asp)
c.527G>C (p.Arg176Thr)
c.285G>C (p.Glu95Asp)
c.432G>C (p.Glu144Asp)
c.493G>C (p.Gly165Arg)
n.923G>C
c.471G>C (p.Glu157Asp)
c.549G>C (p.Glu183Asp)
c.660G>C (p.Glu220Asp)
c.574G>C (p.Gly192Arg)
19g.1106450G=CA2317520672GPX4c.663G= (p.Glu221=)
c.532G= (p.Gly178=)
c.546G= (p.Glu182=)
c.168G= (p.Glu56=)
c.552G= (p.Glu184=)
c.527G= (p.Arg176=)
c.285G= (p.Glu95=)
c.432G= (p.Glu144=)
c.493G= (p.Gly165=)
n.923G=
c.471G= (p.Glu157=)
c.549G= (p.Glu183=)
c.660G= (p.Glu220=)
c.574G= (p.Gly192=)
19g.1106450G>TCA9037484GPX4c.663G>T (p.Glu221Asp)
c.532G>T (p.Gly178Ter)
c.546G>T (p.Glu182Asp)
c.168G>T (p.Glu56Asp)
c.552G>T (p.Glu184Asp)
c.527G>T (p.Arg176Met)
c.285G>T (p.Glu95Asp)
c.432G>T (p.Glu144Asp)
c.493G>T (p.Gly165Ter)
n.923G>T
c.471G>T (p.Glu157Asp)
c.549G>T (p.Glu183Asp)
c.660G>T (p.Glu220Asp)
c.574G>T (p.Gly192Ter)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106451G>ACA402940130GPX4c.664G>A (p.Glu222Lys)
c.533G>A (p.Gly178Glu)
c.547G>A (p.Glu183Lys)
c.169G>A (p.Glu57Lys)
c.553G>A (p.Glu185Lys)
c.528G>A (p.Arg176=)
c.286G>A (p.Glu96Lys)
c.433G>A (p.Glu145Lys)
c.494G>A (p.Gly165Glu)
n.924G>A
c.472G>A (p.Glu158Lys)
c.550G>A (p.Glu184Lys)
c.661G>A (p.Glu221Lys)
c.575G>A (p.Gly192Glu)
 gnomAD v4
19g.1106451G>CCA402940133GPX4c.664G>C (p.Glu222Gln)
c.533G>C (p.Gly178Ala)
c.547G>C (p.Glu183Gln)
c.169G>C (p.Glu57Gln)
c.553G>C (p.Glu185Gln)
c.528G>C (p.Arg176Ser)
c.286G>C (p.Glu96Gln)
c.433G>C (p.Glu145Gln)
c.494G>C (p.Gly165Ala)
n.924G>C
c.472G>C (p.Glu158Gln)
c.550G>C (p.Glu184Gln)
c.661G>C (p.Glu221Gln)
c.575G>C (p.Gly192Ala)
19g.1106451G>TCA402940137GPX4c.664G>T (p.Glu222Ter)
c.533G>T (p.Gly178Val)
c.547G>T (p.Glu183Ter)
c.169G>T (p.Glu57Ter)
c.553G>T (p.Glu185Ter)
c.528G>T (p.Arg176Ser)
c.286G>T (p.Glu96Ter)
c.433G>T (p.Glu145Ter)
c.494G>T (p.Gly165Val)
n.924G>T
c.472G>T (p.Glu158Ter)
c.550G>T (p.Glu184Ter)
c.661G>T (p.Glu221Ter)
c.575G>T (p.Gly192Val)
19g.1106452A>CCA402940140GPX4c.665A>C (p.Glu222Ala)
c.534A>C (p.Gly178=)
c.548A>C (p.Glu183Ala)
c.170A>C (p.Glu57Ala)
c.554A>C (p.Glu185Ala)
c.529A>C (p.Ser177Arg)
c.287A>C (p.Glu96Ala)
c.434A>C (p.Glu145Ala)
c.495A>C (p.Gly165=)
n.925A>C
c.473A>C (p.Glu158Ala)
c.551A>C (p.Glu184Ala)
c.662A>C (p.Glu221Ala)
c.576A>C (p.Gly192=)
19g.1106452A>GCA402940143GPX4c.665A>G (p.Glu222Gly)
c.534A>G (p.Gly178=)
c.548A>G (p.Glu183Gly)
c.170A>G (p.Glu57Gly)
c.554A>G (p.Glu185Gly)
c.529A>G (p.Ser177Gly)
c.287A>G (p.Glu96Gly)
c.434A>G (p.Glu145Gly)
c.495A>G (p.Gly165=)
n.925A>G
c.473A>G (p.Glu158Gly)
c.551A>G (p.Glu184Gly)
c.662A>G (p.Glu221Gly)
c.576A>G (p.Gly192=)
19g.1106452A>TCA402940146GPX4c.665A>T (p.Glu222Val)
c.534A>T (p.Gly178=)
c.548A>T (p.Glu183Val)
c.170A>T (p.Glu57Val)
c.554A>T (p.Glu185Val)
c.529A>T (p.Ser177Cys)
c.287A>T (p.Glu96Val)
c.434A>T (p.Glu145Val)
c.495A>T (p.Gly165=)
n.925A>T
c.473A>T (p.Glu158Val)
c.551A>T (p.Glu184Val)
c.662A>T (p.Glu221Val)
c.576A>T (p.Gly192=)
19g.1106453G>ACA9037485GPX4c.666G>A (p.Glu222=)
c.535G>A (p.Ala179Thr)
c.549G>A (p.Glu183=)
c.171G>A (p.Glu57=)
c.555G>A (p.Glu185=)
c.530G>A (p.Ser177Asn)
c.288G>A (p.Glu96=)
c.435G>A (p.Glu145=)
c.496G>A (p.Ala166Thr)
n.926G>A
c.474G>A (p.Glu158=)
c.552G>A (p.Glu184=)
c.663G>A (p.Glu221=)
c.577G>A (p.Ala193Thr)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
19g.1106453G>CCA402940153GPX4c.666G>C (p.Glu222Asp)
c.535G>C (p.Ala179Pro)
c.549G>C (p.Glu183Asp)
c.171G>C (p.Glu57Asp)
c.555G>C (p.Glu185Asp)
c.530G>C (p.Ser177Thr)
c.288G>C (p.Glu96Asp)
c.435G>C (p.Glu145Asp)
c.496G>C (p.Ala166Pro)
n.926G>C
c.474G>C (p.Glu158Asp)
c.552G>C (p.Glu184Asp)
c.663G>C (p.Glu221Asp)
c.577G>C (p.Ala193Pro)
19g.1106453G=CA2317520673GPX4c.666G= (p.Glu222=)
c.535G= (p.Ala179=)
c.549G= (p.Glu183=)
c.171G= (p.Glu57=)
c.555G= (p.Glu185=)
c.530G= (p.Ser177=)
c.288G= (p.Glu96=)
c.435G= (p.Glu145=)
c.496G= (p.Ala166=)
n.926G=
c.474G= (p.Glu158=)
c.552G= (p.Glu184=)
c.663G= (p.Glu221=)
c.577G= (p.Ala193=)
19g.1106453G>TCA402940154GPX4c.666G>T (p.Glu222Asp)
c.535G>T (p.Ala179Ser)
c.549G>T (p.Glu183Asp)
c.171G>T (p.Glu57Asp)
c.555G>T (p.Glu185Asp)
c.530G>T (p.Ser177Ile)
c.288G>T (p.Glu96Asp)
c.435G>T (p.Glu145Asp)
c.496G>T (p.Ala166Ser)
n.926G>T
c.474G>T (p.Glu158Asp)
c.552G>T (p.Glu184Asp)
c.663G>T (p.Glu221Asp)
c.577G>T (p.Ala193Ser)
19g.1106454C>ACA402940163GPX4c.667C>A (p.Pro223Thr)
c.536C>A (p.Ala179Asp)
c.550C>A (p.Pro184Thr)
c.172C>A (p.Pro58Thr)
c.556C>A (p.Pro186Thr)
c.531C>A (p.Ser177Arg)
c.289C>A (p.Pro97Thr)
c.436C>A (p.Pro146Thr)
c.497C>A (p.Ala166Asp)
n.927C>A
c.475C>A (p.Pro159Thr)
c.553C>A (p.Pro185Thr)
c.664C>A (p.Pro222Thr)
c.578C>A (p.Ala193Asp)
 dbSNP gnomAD v2 gnomAD v4
19g.1106454C=CA2317520674GPX4c.667C= (p.Pro223=)
c.536C= (p.Ala179=)
c.550C= (p.Pro184=)
c.172C= (p.Pro58=)
c.556C= (p.Pro186=)
c.531C= (p.Ser177=)
c.289C= (p.Pro97=)
c.436C= (p.Pro146=)
c.497C= (p.Ala166=)
n.927C=
c.475C= (p.Pro159=)
c.553C= (p.Pro185=)
c.664C= (p.Pro222=)
c.578C= (p.Ala193=)
19g.1106454C>GCA402940162GPX4c.667C>G (p.Pro223Ala)
c.536C>G (p.Ala179Gly)
c.550C>G (p.Pro184Ala)
c.172C>G (p.Pro58Ala)
c.556C>G (p.Pro186Ala)
c.531C>G (p.Ser177Arg)
c.289C>G (p.Pro97Ala)
c.436C>G (p.Pro146Ala)
c.497C>G (p.Ala166Gly)
n.927C>G
c.475C>G (p.Pro159Ala)
c.553C>G (p.Pro185Ala)
c.664C>G (p.Pro222Ala)
c.578C>G (p.Ala193Gly)
19g.1106454C>TCA402940159GPX4c.667C>T (p.Pro223Ser)
c.536C>T (p.Ala179Val)
c.550C>T (p.Pro184Ser)
c.172C>T (p.Pro58Ser)
c.556C>T (p.Pro186Ser)
c.531C>T (p.Ser177=)
c.289C>T (p.Pro97Ser)
c.436C>T (p.Pro146Ser)
c.497C>T (p.Ala166Val)
n.927C>T
c.475C>T (p.Pro159Ser)
c.553C>T (p.Pro185Ser)
c.664C>T (p.Pro222Ser)
c.578C>T (p.Ala193Val)
19g.1106455C>ACA402940164GPX4c.668C>A (p.Pro223His)
c.537C>A (p.Ala179=)
c.551C>A (p.Pro184His)
c.173C>A (p.Pro58His)
c.557C>A (p.Pro186His)
c.532C>A (p.Pro178Thr)
c.290C>A (p.Pro97His)
c.437C>A (p.Pro146His)
c.498C>A (p.Ala166=)
n.928C>A
c.476C>A (p.Pro159His)
c.554C>A (p.Pro185His)
c.665C>A (p.Pro222His)
c.579C>A (p.Ala193=)
19g.1106455C>GCA402940169GPX4c.668C>G (p.Pro223Arg)
c.537C>G (p.Ala179=)
c.551C>G (p.Pro184Arg)
c.173C>G (p.Pro58Arg)
c.557C>G (p.Pro186Arg)
c.532C>G (p.Pro178Ala)
c.290C>G (p.Pro97Arg)
c.437C>G (p.Pro146Arg)
c.498C>G (p.Ala166=)
n.928C>G
c.476C>G (p.Pro159Arg)
c.554C>G (p.Pro185Arg)
c.665C>G (p.Pro222Arg)
c.579C>G (p.Ala193=)
19g.1106455C>TCA402940165GPX4c.668C>T (p.Pro223Leu)
c.537C>T (p.Ala179=)
c.551C>T (p.Pro184Leu)
c.173C>T (p.Pro58Leu)
c.557C>T (p.Pro186Leu)
c.532C>T (p.Pro178Ser)
c.290C>T (p.Pro97Leu)
c.437C>T (p.Pro146Leu)
c.498C>T (p.Ala166=)
n.928C>T
c.476C>T (p.Pro159Leu)
c.554C>T (p.Pro185Leu)
c.665C>T (p.Pro222Leu)
c.579C>T (p.Ala193=)
 gnomAD v4
19g.1106456C>ACA402940173GPX4c.669C>A (p.Pro223=)
c.538C>A (p.Pro180Thr)
c.552C>A (p.Pro184=)
c.174C>A (p.Pro58=)
c.558C>A (p.Pro186=)
c.533C>A (p.Pro178His)
c.291C>A (p.Pro97=)
c.438C>A (p.Pro146=)
c.499C>A (p.Pro167Thr)
n.929C>A
c.477C>A (p.Pro159=)
c.555C>A (p.Pro185=)
c.666C>A (p.Pro222=)
c.580C>A (p.Pro194Thr)
19g.1106456C=CA2317520675GPX4c.669C= (p.Pro223=)
c.538C= (p.Pro180=)
c.552C= (p.Pro184=)
c.174C= (p.Pro58=)
c.558C= (p.Pro186=)
c.533C= (p.Pro178=)
c.291C= (p.Pro97=)
c.438C= (p.Pro146=)
c.499C= (p.Pro167=)
n.929C=
c.477C= (p.Pro159=)
c.555C= (p.Pro185=)
c.666C= (p.Pro222=)
c.580C= (p.Pro194=)
19g.1106456C>GCA402940175GPX4c.669C>G (p.Pro223=)
c.538C>G (p.Pro180Ala)
c.552C>G (p.Pro184=)
c.174C>G (p.Pro58=)
c.558C>G (p.Pro186=)
c.533C>G (p.Pro178Arg)
c.291C>G (p.Pro97=)
c.438C>G (p.Pro146=)
c.499C>G (p.Pro167Ala)
n.929C>G
c.477C>G (p.Pro159=)
c.555C>G (p.Pro185=)
c.666C>G (p.Pro222=)
c.580C>G (p.Pro194Ala)
 gnomAD v4
19g.1106456C>TCA402940176GPX4c.669C>T (p.Pro223=)
c.538C>T (p.Pro180Ser)
c.552C>T (p.Pro184=)
c.174C>T (p.Pro58=)
c.558C>T (p.Pro186=)
c.533C>T (p.Pro178Leu)
c.291C>T (p.Pro97=)
c.438C>T (p.Pro146=)
c.499C>T (p.Pro167Ser)
n.929C>T
c.477C>T (p.Pro159=)
c.555C>T (p.Pro185=)
c.666C>T (p.Pro222=)
c.580C>T (p.Pro194Ser)
 dbSNP gnomAD v4

Number of alleles fetched