Canonical Allele Identifier: CA288456206

Gene: TOP3A

Genomic Alleles

HGVS	Genome Assembly
NC_000017.11:g.18302718G>A , CM000679.2:g.18302718G>A	GRCh38
NC_000017.10:g.18206032G>A , CM000679.1:g.18206032G>A	GRCh37
NC_000017.9:g.18146757G>A	NCBI36

Transcript Alleles

HGVS	Amino-acid Change
NM_004618.5:c.505C>T MANE Select	NP_004609.1:p.Pro169Ser
ENST00000321105.10:c.505C>T MANE Select	ENSP00000321636.5:p.Pro169Ser
NM_001320759.1:c.220C>T	NP_001307688.1:p.Pro74Ser
NM_001320759.2:c.220C>T	NP_001307688.1:p.Pro74Ser
NM_004618.3:c.505C>T	NP_004609.1:p.Pro169Ser
NM_004618.4:c.505C>T	NP_004609.1:p.Pro169Ser
ENST00000321105.9:c.505C>T	ENSP00000321636.5:p.Pro169Ser
ENST00000461127.5:c.*123C>T	ENSP00000464338.1:n.*123C>T
ENST00000469739.6:n.384C>T
ENST00000542570.5:c.505C>T	ENSP00000442336.2:p.Pro169Ser
ENST00000580095.5:c.430C>T	ENSP00000462790.1:p.Pro144Ser
ENST00000582981.5:c.*161C>T	ENSP00000462378.1:n.*161C>T
ENST00000583804.2:n.373C>T
ENST00000584582.5:c.*161C>T	ENSP00000462136.1:n.*161C>T
ENST00000584669.5:n.548C>T
XM_005256776.2:c.220C>T	XP_005256833.1:p.Pro74Ser
XM_011524000.1:c.505C>T	XP_011522302.1:p.Pro169Ser
XM_011524001.1:c.-698C>T	XP_011522303.1:n.-698C>T
XM_011524001.2:c.-698C>T	XP_011522303.1:n.-698C>T
XM_024450903.1:c.-417C>T	XP_024306671.1:n.-417C>T
XR_001752601.2:n.723C>T