Canonical Allele Identifier: CA2589711790

Gene: APP

Linked Data

• gnomAD v3: 21-25891809-G-GCCCAC
• gnomAD v4: 21-25891809-G-GCCCAC

Genomic Alleles

HGVS	Genome Assembly
NC_000021.9:g.25891811_25891815dup , CM000683.2:g.25891811_25891815dup	GRCh38
NC_000021.8:g.27264123_27264127dup , CM000683.1:g.27264123_27264127dup	GRCh37
NC_000021.7:g.26185994_26185998dup	NCBI36
NG_007376.1:g.284007_284011dup
NG_007376.2:g.284315_284319dup

Transcript Alleles

HGVS	Amino-acid change
ENST00000707132.1:n.2086_2090dup
ENST00000707133.1:n.516_520dup
ENST00000707134.1:n.785_789dup
ENST00000346798.8:c.2119_2123dup MANE Select	ENSP00000284981.4:p.Gly709TrpfsTer6
ENST00000346798.7:c.2119_2123dup	ENSP00000284981.4:p.Gly709TrpfsTer6
ENST00000348990.9:c.1894_1898dup	ENSP00000345463.5:p.Gly634TrpfsTer6
ENST00000354192.7:c.1726_1730dup	ENSP00000346129.3:p.Gly578TrpfsTer6
ENST00000357903.7:c.2062_2066dup	ENSP00000350578.3:p.Gly690TrpfsTer6
ENST00000358918.7:c.2065_2069dup	ENSP00000351796.3:p.Gly691TrpfsTer6
ENST00000359726.7:c.1789_1793dup	ENSP00000352760.4:p.Gly599TrpfsTer6
ENST00000439274.6:c.1951_1955dup	ENSP00000398879.2:p.Gly653TrpfsTer6
ENST00000440126.7:c.2047_2051dup	ENSP00000387483.2:p.Gly685TrpfsTer6
ENST00000464867.1:n.466_470dup
NM_000484.3:c.2119_2123dup	NP_000475.1:p.Gly709TrpfsTer6
NM_001136016.3:c.2047_2051dup	NP_001129488.1:p.Gly685TrpfsTer6
NM_001136129.2:c.1726_1730dup	NP_001129601.1:p.Gly578TrpfsTer6
NM_001136130.2:c.1951_1955dup	NP_001129602.1:p.Gly653TrpfsTer6
NM_001136131.2:c.1789_1793dup	NP_001129603.1:p.Gly599TrpfsTer6
NM_001204301.1:c.2065_2069dup	NP_001191230.1:p.Gly691TrpfsTer6
NM_001204302.1:c.2008_2012dup	NP_001191231.1:p.Gly672TrpfsTer6
NM_001204303.1:c.1840_1844dup	NP_001191232.1:p.Gly616TrpfsTer6
NM_201413.2:c.2062_2066dup	NP_958816.1:p.Gly690TrpfsTer6
NM_201414.2:c.1894_1898dup	NP_958817.1:p.Gly634TrpfsTer6
NM_000484.4:c.2119_2123dup MANE Select	NP_000475.1:p.Gly709TrpfsTer6
NM_001136129.3:c.1726_1730dup	NP_001129601.1:p.Gly578TrpfsTer6
NM_001136130.3:c.1951_1955dup	NP_001129602.1:p.Gly653TrpfsTer6
NM_001204301.2:c.2065_2069dup	NP_001191230.1:p.Gly691TrpfsTer6
NM_001204302.2:c.2008_2012dup	NP_001191231.1:p.Gly672TrpfsTer6
NM_001204303.2:c.1840_1844dup	NP_001191232.1:p.Gly616TrpfsTer6
NM_201413.3:c.2062_2066dup	NP_958816.1:p.Gly690TrpfsTer6
NM_201414.3:c.1894_1898dup	NP_958817.1:p.Gly634TrpfsTer6
NM_001136131.3:c.1789_1793dup	NP_001129603.1:p.Gly599TrpfsTer6
NM_001385253.1:c.1951_1955dup	NP_001372182.1:p.Gly653TrpfsTer6