Chr Mutation (hg38) CAid Gene Transcript Linkouts
1g.97193108T>ACA341373346DPYD,DPYD-AS1c.2583A>T (p.Lys861Asn)
n.65-72306T>A
c.2367A>T (p.Lys789Asn)
c.2472A>T (p.Lys824Asn)
c.2088A>T (p.Lys696Asn)
1g.97193108T>CCA419137089DPYD,DPYD-AS1c.2583A>G (p.Lys861=)
n.65-72306T>C
c.2367A>G (p.Lys789=)
c.2472A>G (p.Lys824=)
c.2088A>G (p.Lys696=)
 gnomAD v4
1g.97193108T>GCA341373347DPYD,DPYD-AS1c.2583A>C (p.Lys861Asn)
n.65-72306T>G
c.2367A>C (p.Lys789Asn)
c.2472A>C (p.Lys824Asn)
c.2088A>C (p.Lys696Asn)
1g.97193109T>ACA341373348DPYD,DPYD-AS1c.2582A>T (p.Lys861Ile)
n.65-72305T>A
c.2366A>T (p.Lys789Ile)
c.2471A>T (p.Lys824Ile)
c.2087A>T (p.Lys696Ile)
1g.97193109T>CCA963003DPYD,DPYD-AS1c.2582A>G (p.Lys861Arg)
n.65-72305T>C
c.2366A>G (p.Lys789Arg)
c.2471A>G (p.Lys824Arg)
c.2087A>G (p.Lys696Arg)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193109T>GCA341373349DPYD,DPYD-AS1c.2582A>C (p.Lys861Thr)
n.65-72305T>G
c.2366A>C (p.Lys789Thr)
c.2471A>C (p.Lys824Thr)
c.2087A>C (p.Lys696Thr)
1g.97193109T=CA1140699098DPYD,DPYD-AS1c.2582A= (p.Lys861=)
n.65-72305T=
c.2366A= (p.Lys789=)
c.2471A= (p.Lys824=)
c.2087A= (p.Lys696=)
1g.97193110T>ACA341373350DPYD,DPYD-AS1c.2581A>T (p.Lys861Ter)
n.65-72304T>A
c.2365A>T (p.Lys789Ter)
c.2470A>T (p.Lys824Ter)
c.2086A>T (p.Lys696Ter)
1g.97193110T>CCA341373351DPYD,DPYD-AS1c.2581A>G (p.Lys861Glu)
n.65-72304T>C
c.2365A>G (p.Lys789Glu)
c.2470A>G (p.Lys824Glu)
c.2086A>G (p.Lys696Glu)
1g.97193110T>GCA341373352DPYD,DPYD-AS1c.2581A>C (p.Lys861Gln)
n.65-72304T>G
c.2365A>C (p.Lys789Gln)
c.2470A>C (p.Lys824Gln)
c.2086A>C (p.Lys696Gln)
1g.97193111_97193112delCA913078543DPYD,DPYD-AS1c.2580_2581del (p.Lys861ArgfsTer9)
n.65-72303_65-72302del
c.2364_2365del (p.Lys789ArgfsTer9)
c.2469_2470del (p.Lys824ArgfsTer9)
c.2085_2086del (p.Lys696ArgfsTer9)
1g.97193111C>ACA341373353DPYD,DPYD-AS1c.2580G>T (p.Gln860His)
n.65-72303C>A
c.2364G>T (p.Gln788His)
c.2469G>T (p.Gln823His)
c.2085G>T (p.Gln695His)
1g.97193111C>GCA341373354DPYD,DPYD-AS1c.2580G>C (p.Gln860His)
n.65-72303C>G
c.2364G>C (p.Gln788His)
c.2469G>C (p.Gln823His)
c.2085G>C (p.Gln695His)
1g.97193111C>TCA419137090DPYD,DPYD-AS1c.2580G>A (p.Gln860=)
n.65-72303C>T
c.2364G>A (p.Gln788=)
c.2469G>A (p.Gln823=)
c.2085G>A (p.Gln695=)
 COSMIC
1g.97193111_97193112delinsCTCA1182758251DPYD,DPYD-AS1c.2579_2580delinsAG (p.Gln860=)
n.65-72303_65-72302delinsCT
c.2363_2364delinsAG (p.Gln788=)
c.2468_2469delinsAG (p.Gln823=)
c.2084_2085delinsAG (p.Gln695=)
1g.97193112delCA963004DPYD,DPYD-AS1c.2579del (p.Gln860ArgfsTer9)
n.65-72302del
c.2363del (p.Gln788ArgfsTer9)
c.2468del (p.Gln823ArgfsTer9)
c.2084del (p.Gln695ArgfsTer9)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193112T>ACA341373357DPYD,DPYD-AS1c.2579A>T (p.Gln860Leu)
n.65-72302T>A
c.2363A>T (p.Gln788Leu)
c.2468A>T (p.Gln823Leu)
c.2084A>T (p.Gln695Leu)
1g.97193112T>CCA341373356DPYD,DPYD-AS1c.2579A>G (p.Gln860Arg)
n.65-72302T>C
c.2363A>G (p.Gln788Arg)
c.2468A>G (p.Gln823Arg)
c.2084A>G (p.Gln695Arg)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4 COSMIC
1g.97193112T>GCA341373355DPYD,DPYD-AS1c.2579A>C (p.Gln860Pro)
n.65-72302T>G
c.2363A>C (p.Gln788Pro)
c.2468A>C (p.Gln823Pro)
c.2084A>C (p.Gln695Pro)
1g.97193112T=CA1148428135DPYD,DPYD-AS1c.2579A= (p.Gln860=)
n.65-72302T=
c.2363A= (p.Gln788=)
c.2468A= (p.Gln823=)
c.2084A= (p.Gln695=)
1g.97193113G>ACA341373358DPYD,DPYD-AS1c.2578C>T (p.Gln860Ter)
n.65-72301G>A
c.2362C>T (p.Gln788Ter)
c.2467C>T (p.Gln823Ter)
c.2083C>T (p.Gln695Ter)
 gnomAD v4
1g.97193113G>CCA341373359DPYD,DPYD-AS1c.2578C>G (p.Gln860Glu)
n.65-72301G>C
c.2362C>G (p.Gln788Glu)
c.2467C>G (p.Gln823Glu)
c.2083C>G (p.Gln695Glu)
1g.97193113G>TCA341373360DPYD,DPYD-AS1c.2578C>A (p.Gln860Lys)
n.65-72301G>T
c.2362C>A (p.Gln788Lys)
c.2467C>A (p.Gln823Lys)
c.2083C>A (p.Gln695Lys)
1g.97193114G>ACA419137091DPYD,DPYD-AS1c.2577C>T (p.His859=)
n.65-72300G>A
c.2361C>T (p.His787=)
c.2466C>T (p.His822=)
c.2082C>T (p.His694=)
 gnomAD v4
1g.97193114G>CCA341373361DPYD,DPYD-AS1c.2577C>G (p.His859Gln)
n.65-72300G>C
c.2361C>G (p.His787Gln)
c.2466C>G (p.His822Gln)
c.2082C>G (p.His694Gln)
1g.97193114G>TCA341373362DPYD,DPYD-AS1c.2577C>A (p.His859Gln)
n.65-72300G>T
c.2361C>A (p.His787Gln)
c.2466C>A (p.His822Gln)
c.2082C>A (p.His694Gln)
1g.97193115T>ACA341373363DPYD,DPYD-AS1c.2576A>T (p.His859Leu)
n.65-72299T>A
c.2360A>T (p.His787Leu)
c.2465A>T (p.His822Leu)
c.2081A>T (p.His694Leu)
1g.97193115T>CCA341373364DPYD,DPYD-AS1c.2576A>G (p.His859Arg)
n.65-72299T>C
c.2360A>G (p.His787Arg)
c.2465A>G (p.His822Arg)
c.2081A>G (p.His694Arg)
1g.97193115T>GCA341373365DPYD,DPYD-AS1c.2576A>C (p.His859Pro)
n.65-72299T>G
c.2360A>C (p.His787Pro)
c.2465A>C (p.His822Pro)
c.2081A>C (p.His694Pro)
1g.97193116G>ACA341373366DPYD,DPYD-AS1c.2575C>T (p.His859Tyr)
n.65-72298G>A
c.2359C>T (p.His787Tyr)
c.2464C>T (p.His822Tyr)
c.2080C>T (p.His694Tyr)
1g.97193116G>CCA341373367DPYD,DPYD-AS1c.2575C>G (p.His859Asp)
n.65-72298G>C
c.2359C>G (p.His787Asp)
c.2464C>G (p.His822Asp)
c.2080C>G (p.His694Asp)
1g.97193116G>TCA341373368DPYD,DPYD-AS1c.2575C>A (p.His859Asn)
n.65-72298G>T
c.2359C>A (p.His787Asn)
c.2464C>A (p.His822Asn)
c.2080C>A (p.His694Asn)
 gnomAD v4
1g.97193117A>CCA341373369DPYD,DPYD-AS1c.2574T>G (p.Ser858Arg)
n.65-72297A>C
c.2358T>G (p.Ser786Arg)
c.2463T>G (p.Ser821Arg)
c.2079T>G (p.Ser693Arg)
1g.97193117A>GCA419137092DPYD,DPYD-AS1c.2574T>C (p.Ser858=)
n.65-72297A>G
c.2358T>C (p.Ser786=)
c.2463T>C (p.Ser821=)
c.2079T>C (p.Ser693=)
 gnomAD v4
1g.97193117A>TCA341373370DPYD,DPYD-AS1c.2574T>A (p.Ser858Arg)
n.65-72297A>T
c.2358T>A (p.Ser786Arg)
c.2463T>A (p.Ser821Arg)
c.2079T>A (p.Ser693Arg)
1g.97193118C>ACA341373373DPYD,DPYD-AS1c.2573G>T (p.Ser858Ile)
n.65-72296C>A
c.2357G>T (p.Ser786Ile)
c.2462G>T (p.Ser821Ile)
c.2078G>T (p.Ser693Ile)
1g.97193118C=CA1182758252DPYD,DPYD-AS1c.2573G= (p.Ser858=)
n.65-72296C=
c.2357G= (p.Ser786=)
c.2462G= (p.Ser821=)
c.2078G= (p.Ser693=)
1g.97193118C>GCA341373372DPYD,DPYD-AS1c.2573G>C (p.Ser858Thr)
n.65-72296C>G
c.2357G>C (p.Ser786Thr)
c.2462G>C (p.Ser821Thr)
c.2078G>C (p.Ser693Thr)
1g.97193118C>TCA341373371DPYD,DPYD-AS1c.2573G>A (p.Ser858Asn)
n.65-72296C>T
c.2357G>A (p.Ser786Asn)
c.2462G>A (p.Ser821Asn)
c.2078G>A (p.Ser693Asn)
 dbSNP
1g.97193119T>ACA341373376DPYD,DPYD-AS1c.2572A>T (p.Ser858Cys)
n.65-72295T>A
c.2356A>T (p.Ser786Cys)
c.2461A>T (p.Ser821Cys)
c.2077A>T (p.Ser693Cys)
1g.97193119T>CCA341373374DPYD,DPYD-AS1c.2572A>G (p.Ser858Gly)
n.65-72295T>C
c.2356A>G (p.Ser786Gly)
c.2461A>G (p.Ser821Gly)
c.2077A>G (p.Ser693Gly)
1g.97193119T>GCA341373375DPYD,DPYD-AS1c.2572A>C (p.Ser858Arg)
n.65-72295T>G
c.2356A>C (p.Ser786Arg)
c.2461A>C (p.Ser821Arg)
c.2077A>C (p.Ser693Arg)
 dbSNP
1g.97193119T=CA1182758253DPYD,DPYD-AS1c.2572A= (p.Ser858=)
n.65-72295T=
c.2356A= (p.Ser786=)
c.2461A= (p.Ser821=)
c.2077A= (p.Ser693=)
1g.97193120C>ACA419137093DPYD,DPYD-AS1c.2571G>T (p.Val857=)
n.65-72294C>A
c.2355G>T (p.Val785=)
c.2460G>T (p.Val820=)
c.2076G>T (p.Val692=)
1g.97193120C>GCA419137094DPYD,DPYD-AS1c.2571G>C (p.Val857=)
n.65-72294C>G
c.2355G>C (p.Val785=)
c.2460G>C (p.Val820=)
c.2076G>C (p.Val692=)
1g.97193120C>TCA419137095DPYD,DPYD-AS1c.2571G>A (p.Val857=)
n.65-72294C>T
c.2355G>A (p.Val785=)
c.2460G>A (p.Val820=)
c.2076G>A (p.Val692=)
1g.97193121A>CCA341373377DPYD,DPYD-AS1c.2570T>G (p.Val857Gly)
n.65-72293A>C
c.2354T>G (p.Val785Gly)
c.2459T>G (p.Val820Gly)
c.2075T>G (p.Val692Gly)
1g.97193121A>GCA341373378DPYD,DPYD-AS1c.2570T>C (p.Val857Ala)
n.65-72293A>G
c.2354T>C (p.Val785Ala)
c.2459T>C (p.Val820Ala)
c.2075T>C (p.Val692Ala)
1g.97193121A>TCA341373379DPYD,DPYD-AS1c.2570T>A (p.Val857Glu)
n.65-72293A>T
c.2354T>A (p.Val785Glu)
c.2459T>A (p.Val820Glu)
c.2075T>A (p.Val692Glu)
1g.97193122C>ACA341373380DPYD,DPYD-AS1c.2569G>T (p.Val857Leu)
n.65-72292C>A
c.2353G>T (p.Val785Leu)
c.2458G>T (p.Val820Leu)
c.2074G>T (p.Val692Leu)
1g.97193122C>GCA341373381DPYD,DPYD-AS1c.2569G>C (p.Val857Leu)
n.65-72292C>G
c.2353G>C (p.Val785Leu)
c.2458G>C (p.Val820Leu)
c.2074G>C (p.Val692Leu)
 gnomAD v4
1g.97193122C>TCA341373382DPYD,DPYD-AS1c.2569G>A (p.Val857Met)
n.65-72292C>T
c.2353G>A (p.Val785Met)
c.2458G>A (p.Val820Met)
c.2074G>A (p.Val692Met)
1g.97193123A=CA1144808887DPYD,DPYD-AS1c.2568T= (p.Thr856=)
n.65-72291A=
c.2352T= (p.Thr784=)
c.2457T= (p.Thr819=)
c.2073T= (p.Thr691=)
1g.97193123A>CCA419137096DPYD,DPYD-AS1c.2568T>G (p.Thr856=)
n.65-72291A>C
c.2352T>G (p.Thr784=)
c.2457T>G (p.Thr819=)
c.2073T>G (p.Thr691=)
 dbSNP gnomAD v4
1g.97193123A>GCA963005DPYD,DPYD-AS1c.2568T>C (p.Thr856=)
n.65-72291A>G
c.2352T>C (p.Thr784=)
c.2457T>C (p.Thr819=)
c.2073T>C (p.Thr691=)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193123A>TCA419137097DPYD,DPYD-AS1c.2568T>A (p.Thr856=)
n.65-72291A>T
c.2352T>A (p.Thr784=)
c.2457T>A (p.Thr819=)
c.2073T>A (p.Thr691=)
1g.97193124G>ACA963006DPYD,DPYD-AS1c.2567C>T (p.Thr856Ile)
n.65-72290G>A
c.2351C>T (p.Thr784Ile)
c.2456C>T (p.Thr819Ile)
c.2072C>T (p.Thr691Ile)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193124G>CCA341373383DPYD,DPYD-AS1c.2567C>G (p.Thr856Ser)
n.65-72290G>C
c.2351C>G (p.Thr784Ser)
c.2456C>G (p.Thr819Ser)
c.2072C>G (p.Thr691Ser)
 gnomAD v4
1g.97193124G=CA1182758254DPYD,DPYD-AS1c.2567C= (p.Thr856=)
n.65-72290G=
c.2351C= (p.Thr784=)
c.2456C= (p.Thr819=)
c.2072C= (p.Thr691=)
1g.97193124G>TCA341373384DPYD,DPYD-AS1c.2567C>A (p.Thr856Asn)
n.65-72290G>T
c.2351C>A (p.Thr784Asn)
c.2456C>A (p.Thr819Asn)
c.2072C>A (p.Thr691Asn)
1g.97193125T>ACA341373386DPYD,DPYD-AS1c.2566A>T (p.Thr856Ser)
n.65-72289T>A
c.2350A>T (p.Thr784Ser)
c.2455A>T (p.Thr819Ser)
c.2071A>T (p.Thr691Ser)
1g.97193125T>CCA341373387DPYD,DPYD-AS1c.2566A>G (p.Thr856Ala)
n.65-72289T>C
c.2350A>G (p.Thr784Ala)
c.2455A>G (p.Thr819Ala)
c.2071A>G (p.Thr691Ala)
1g.97193125T>GCA341373385DPYD,DPYD-AS1c.2566A>C (p.Thr856Pro)
n.65-72289T>G
c.2350A>C (p.Thr784Pro)
c.2455A>C (p.Thr819Pro)
c.2071A>C (p.Thr691Pro)
1g.97193126A=CA1182758255DPYD,DPYD-AS1c.2565T= (p.Ala855=)
n.65-72288A=
c.2349T= (p.Ala783=)
c.2454T= (p.Ala818=)
c.2070T= (p.Ala690=)
1g.97193126A>CCA419137098DPYD,DPYD-AS1c.2565T>G (p.Ala855=)
n.65-72288A>C
c.2349T>G (p.Ala783=)
c.2454T>G (p.Ala818=)
c.2070T>G (p.Ala690=)
1g.97193126A>GCA419137099DPYD,DPYD-AS1c.2565T>C (p.Ala855=)
n.65-72288A>G
c.2349T>C (p.Ala783=)
c.2454T>C (p.Ala818=)
c.2070T>C (p.Ala690=)
1g.97193126A>TCA419137100DPYD,DPYD-AS1c.2565T>A (p.Ala855=)
n.65-72288A>T
c.2349T>A (p.Ala783=)
c.2454T>A (p.Ala818=)
c.2070T>A (p.Ala690=)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
1g.97193127G>ACA341373388DPYD,DPYD-AS1c.2564C>T (p.Ala855Val)
n.65-72287G>A
c.2348C>T (p.Ala783Val)
c.2453C>T (p.Ala818Val)
c.2069C>T (p.Ala690Val)
1g.97193127G>CCA27471512DPYD,DPYD-AS1c.2564C>G (p.Ala855Gly)
n.65-72287G>C
c.2348C>G (p.Ala783Gly)
c.2453C>G (p.Ala818Gly)
c.2069C>G (p.Ala690Gly)
 ClinVar dbSNP gnomAD v2 gnomAD v3 gnomAD v4
1g.97193127G=CA1182758256DPYD,DPYD-AS1c.2564C= (p.Ala855=)
n.65-72287G=
c.2348C= (p.Ala783=)
c.2453C= (p.Ala818=)
c.2069C= (p.Ala690=)
1g.97193127G>TCA341373389DPYD,DPYD-AS1c.2564C>A (p.Ala855Asp)
n.65-72287G>T
c.2348C>A (p.Ala783Asp)
c.2453C>A (p.Ala818Asp)
c.2069C>A (p.Ala690Asp)
1g.97193128C>ACA341373390DPYD,DPYD-AS1c.2563G>T (p.Ala855Ser)
n.65-72286C>A
c.2347G>T (p.Ala783Ser)
c.2452G>T (p.Ala818Ser)
c.2068G>T (p.Ala690Ser)
1g.97193128C=CA1182758257DPYD,DPYD-AS1c.2563G= (p.Ala855=)
n.65-72286C=
c.2347G= (p.Ala783=)
c.2452G= (p.Ala818=)
c.2068G= (p.Ala690=)
1g.97193128C>GCA341373391DPYD,DPYD-AS1c.2563G>C (p.Ala855Pro)
n.65-72286C>G
c.2347G>C (p.Ala783Pro)
c.2452G>C (p.Ala818Pro)
c.2068G>C (p.Ala690Pro)
1g.97193128C>TCA963007DPYD,DPYD-AS1c.2563G>A (p.Ala855Thr)
n.65-72286C>T
c.2347G>A (p.Ala783Thr)
c.2452G>A (p.Ala818Thr)
c.2068G>A (p.Ala690Thr)
 dbSNP ExAC gnomAD v2 gnomAD v4
1g.97193129T>ACA419137103DPYD,DPYD-AS1c.2562A>T (p.Pro854=)
n.65-72285T>A
c.2346A>T (p.Pro782=)
c.2451A>T (p.Pro817=)
c.2067A>T (p.Pro689=)
1g.97193129T>CCA419137102DPYD,DPYD-AS1c.2562A>G (p.Pro854=)
n.65-72285T>C
c.2346A>G (p.Pro782=)
c.2451A>G (p.Pro817=)
c.2067A>G (p.Pro689=)
1g.97193129T>GCA419137101DPYD,DPYD-AS1c.2562A>C (p.Pro854=)
n.65-72285T>G
c.2346A>C (p.Pro782=)
c.2451A>C (p.Pro817=)
c.2067A>C (p.Pro689=)
1g.97193129_97193132dupCA2744694191DPYD,DPYD-AS1c.2559_2562dup (p.Ala855SerfsTer17)
n.65-72285_65-72282dup
c.2343_2346dup (p.Ala783SerfsTer17)
c.2448_2451dup (p.Ala818SerfsTer17)
c.2064_2067dup (p.Ala690SerfsTer17)
1g.97193130G>ACA341373392DPYD,DPYD-AS1c.2561C>T (p.Pro854Leu)
n.65-72284G>A
c.2345C>T (p.Pro782Leu)
c.2450C>T (p.Pro817Leu)
c.2066C>T (p.Pro689Leu)
1g.97193130G>CCA341373394DPYD,DPYD-AS1c.2561C>G (p.Pro854Arg)
n.65-72284G>C
c.2345C>G (p.Pro782Arg)
c.2450C>G (p.Pro817Arg)
c.2066C>G (p.Pro689Arg)
 dbSNP gnomAD v3 gnomAD v4
1g.97193130G=CA1182758258DPYD,DPYD-AS1c.2561C= (p.Pro854=)
n.65-72284G=
c.2345C= (p.Pro782=)
c.2450C= (p.Pro817=)
c.2066C= (p.Pro689=)
1g.97193130G>TCA341373393DPYD,DPYD-AS1c.2561C>A (p.Pro854Gln)
n.65-72284G>T
c.2345C>A (p.Pro782Gln)
c.2450C>A (p.Pro817Gln)
c.2066C>A (p.Pro689Gln)
 gnomAD v4
1g.97193131G>ACA341373395DPYD,DPYD-AS1c.2560C>T (p.Pro854Ser)
n.65-72283G>A
c.2344C>T (p.Pro782Ser)
c.2449C>T (p.Pro817Ser)
c.2065C>T (p.Pro689Ser)
 gnomAD v4
1g.97193131G>CCA341373396DPYD,DPYD-AS1c.2560C>G (p.Pro854Ala)
n.65-72283G>C
c.2344C>G (p.Pro782Ala)
c.2449C>G (p.Pro817Ala)
c.2065C>G (p.Pro689Ala)
 dbSNP
1g.97193131G=CA1182758259DPYD,DPYD-AS1c.2560C= (p.Pro854=)
n.65-72283G=
c.2344C= (p.Pro782=)
c.2449C= (p.Pro817=)
c.2065C= (p.Pro689=)
1g.97193131G>TCA341373397DPYD,DPYD-AS1c.2560C>A (p.Pro854Thr)
n.65-72283G>T
c.2344C>A (p.Pro782Thr)
c.2449C>A (p.Pro817Thr)
c.2065C>A (p.Pro689Thr)
1g.97193132A>CCA341373398DPYD,DPYD-AS1c.2559T>G (p.Ser853Arg)
n.65-72282A>C
c.2343T>G (p.Ser781Arg)
c.2448T>G (p.Ser816Arg)
c.2064T>G (p.Ser688Arg)
1g.97193132A>GCA419137104DPYD,DPYD-AS1c.2559T>C (p.Ser853=)
n.65-72282A>G
c.2343T>C (p.Ser781=)
c.2448T>C (p.Ser816=)
c.2064T>C (p.Ser688=)
1g.97193132A>TCA341373399DPYD,DPYD-AS1c.2559T>A (p.Ser853Arg)
n.65-72282A>T
c.2343T>A (p.Ser781Arg)
c.2448T>A (p.Ser816Arg)
c.2064T>A (p.Ser688Arg)
1g.97193133C>ACA341373402DPYD,DPYD-AS1c.2558G>T (p.Ser853Ile)
n.65-72281C>A
c.2342G>T (p.Ser781Ile)
c.2447G>T (p.Ser816Ile)
c.2063G>T (p.Ser688Ile)
 gnomAD v4
1g.97193133C>GCA341373401DPYD,DPYD-AS1c.2558G>C (p.Ser853Thr)
n.65-72281C>G
c.2342G>C (p.Ser781Thr)
c.2447G>C (p.Ser816Thr)
c.2063G>C (p.Ser688Thr)
1g.97193133C>TCA341373400DPYD,DPYD-AS1c.2558G>A (p.Ser853Asn)
n.65-72281C>T
c.2342G>A (p.Ser781Asn)
c.2447G>A (p.Ser816Asn)
c.2063G>A (p.Ser688Asn)
 COSMIC
1g.97193134T>ACA341373403DPYD,DPYD-AS1c.2557A>T (p.Ser853Cys)
n.65-72280T>A
c.2341A>T (p.Ser781Cys)
c.2446A>T (p.Ser816Cys)
c.2062A>T (p.Ser688Cys)
1g.97193134T>CCA341373405DPYD,DPYD-AS1c.2557A>G (p.Ser853Gly)
n.65-72280T>C
c.2341A>G (p.Ser781Gly)
c.2446A>G (p.Ser816Gly)
c.2062A>G (p.Ser688Gly)
 gnomAD v4
1g.97193134T>GCA341373404DPYD,DPYD-AS1c.2557A>C (p.Ser853Arg)
n.65-72280T>G
c.2341A>C (p.Ser781Arg)
c.2446A>C (p.Ser816Arg)
c.2062A>C (p.Ser688Arg)
 dbSNP gnomAD v4
1g.97193134T=CA1182758260DPYD,DPYD-AS1c.2557A= (p.Ser853=)
n.65-72280T=
c.2341A= (p.Ser781=)
c.2446A= (p.Ser816=)
c.2062A= (p.Ser688=)
1g.97193135C>ACA341373406DPYD,DPYD-AS1c.2556G>T (p.Gln852His)
n.65-72279C>A
c.2340G>T (p.Gln780His)
c.2445G>T (p.Gln815His)
c.2061G>T (p.Gln687His)
1g.97193135C>GCA341373407DPYD,DPYD-AS1c.2556G>C (p.Gln852His)
n.65-72279C>G
c.2340G>C (p.Gln780His)
c.2445G>C (p.Gln815His)
c.2061G>C (p.Gln687His)
1g.97193135C>TCA419137105DPYD,DPYD-AS1c.2556G>A (p.Gln852=)
n.65-72279C>T
c.2340G>A (p.Gln780=)
c.2445G>A (p.Gln815=)
c.2061G>A (p.Gln687=)
1g.97193136T>ACA341373408DPYD,DPYD-AS1c.2555A>T (p.Gln852Leu)
n.65-72278T>A
c.2339A>T (p.Gln780Leu)
c.2444A>T (p.Gln815Leu)
c.2060A>T (p.Gln687Leu)
1g.97193136T>CCA341373409DPYD,DPYD-AS1c.2555A>G (p.Gln852Arg)
n.65-72278T>C
c.2339A>G (p.Gln780Arg)
c.2444A>G (p.Gln815Arg)
c.2060A>G (p.Gln687Arg)
1g.97193136T>GCA341373410DPYD,DPYD-AS1c.2555A>C (p.Gln852Pro)
n.65-72278T>G
c.2339A>C (p.Gln780Pro)
c.2444A>C (p.Gln815Pro)
c.2060A>C (p.Gln687Pro)
1g.97193137G>ACA16040793DPYD,DPYD-AS1c.2554C>T (p.Gln852Ter)
n.65-72277G>A
c.2338C>T (p.Gln780Ter)
c.2443C>T (p.Gln815Ter)
c.2059C>T (p.Gln687Ter)
 ClinVar dbSNP gnomAD v4
1g.97193137G>CCA341373411DPYD,DPYD-AS1c.2554C>G (p.Gln852Glu)
n.65-72277G>C
c.2338C>G (p.Gln780Glu)
c.2443C>G (p.Gln815Glu)
c.2059C>G (p.Gln687Glu)
1g.97193137G=CA1182758261DPYD,DPYD-AS1c.2554C= (p.Gln852=)
n.65-72277G=
c.2338C= (p.Gln780=)
c.2443C= (p.Gln815=)
c.2059C= (p.Gln687=)
1g.97193137G>TCA341373412DPYD,DPYD-AS1c.2554C>A (p.Gln852Lys)
n.65-72277G>T
c.2338C>A (p.Gln780Lys)
c.2443C>A (p.Gln815Lys)
c.2059C>A (p.Gln687Lys)
1g.97193138T>ACA419137106DPYD,DPYD-AS1c.2553A>T (p.Gly851=)
n.65-72276T>A
c.2337A>T (p.Gly779=)
c.2442A>T (p.Gly814=)
c.2058A>T (p.Gly686=)
1g.97193138T>CCA419137107DPYD,DPYD-AS1c.2553A>G (p.Gly851=)
n.65-72276T>C
c.2337A>G (p.Gly779=)
c.2442A>G (p.Gly814=)
c.2058A>G (p.Gly686=)
 gnomAD v4
1g.97193138T>GCA419137108DPYD,DPYD-AS1c.2553A>C (p.Gly851=)
n.65-72276T>G
c.2337A>C (p.Gly779=)
c.2442A>C (p.Gly814=)
c.2058A>C (p.Gly686=)
1g.97193139C>ACA341373413DPYD,DPYD-AS1c.2552G>T (p.Gly851Val)
n.65-72275C>A
c.2336G>T (p.Gly779Val)
c.2441G>T (p.Gly814Val)
c.2057G>T (p.Gly686Val)
1g.97193139C>GCA341373414DPYD,DPYD-AS1c.2552G>C (p.Gly851Ala)
n.65-72275C>G
c.2336G>C (p.Gly779Ala)
c.2441G>C (p.Gly814Ala)
c.2057G>C (p.Gly686Ala)
1g.97193139C>TCA341373415DPYD,DPYD-AS1c.2552G>A (p.Gly851Glu)
n.65-72275C>T
c.2336G>A (p.Gly779Glu)
c.2441G>A (p.Gly814Glu)
c.2057G>A (p.Gly686Glu)
1g.97193140C>ACA341373418DPYD,DPYD-AS1c.2551G>T (p.Gly851Ter)
n.65-72274C>A
c.2335G>T (p.Gly779Ter)
c.2440G>T (p.Gly814Ter)
c.2056G>T (p.Gly686Ter)
1g.97193140C=CA1182758262DPYD,DPYD-AS1c.2551G= (p.Gly851=)
n.65-72274C=
c.2335G= (p.Gly779=)
c.2440G= (p.Gly814=)
c.2056G= (p.Gly686=)
1g.97193140C>GCA341373417DPYD,DPYD-AS1c.2551G>C (p.Gly851Arg)
n.65-72274C>G
c.2335G>C (p.Gly779Arg)
c.2440G>C (p.Gly814Arg)
c.2056G>C (p.Gly686Arg)
1g.97193140C>TCA341373416DPYD,DPYD-AS1c.2551G>A (p.Gly851Arg)
n.65-72274C>T
c.2335G>A (p.Gly779Arg)
c.2440G>A (p.Gly814Arg)
c.2056G>A (p.Gly686Arg)
 dbSNP gnomAD v3 gnomAD v4 COSMIC
1g.97193141A=CA1182758263DPYD,DPYD-AS1c.2550T= (p.Asp850=)
n.65-72273A=
c.2334T= (p.Asp778=)
c.2439T= (p.Asp813=)
c.2055T= (p.Asp685=)
1g.97193141A>CCA341373419DPYD,DPYD-AS1c.2550T>G (p.Asp850Glu)
n.65-72273A>C
c.2334T>G (p.Asp778Glu)
c.2439T>G (p.Asp813Glu)
c.2055T>G (p.Asp685Glu)
1g.97193141A>GCA963008DPYD,DPYD-AS1c.2550T>C (p.Asp850=)
n.65-72273A>G
c.2334T>C (p.Asp778=)
c.2439T>C (p.Asp813=)
c.2055T>C (p.Asp685=)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193141A>TCA341373420DPYD,DPYD-AS1c.2550T>A (p.Asp850Glu)
n.65-72273A>T
c.2334T>A (p.Asp778Glu)
c.2439T>A (p.Asp813Glu)
c.2055T>A (p.Asp685Glu)
1g.97193142T>ACA341373421DPYD,DPYD-AS1c.2549A>T (p.Asp850Val)
n.65-72272T>A
c.2333A>T (p.Asp778Val)
c.2438A>T (p.Asp813Val)
c.2054A>T (p.Asp685Val)
1g.97193142T>CCA963009DPYD,DPYD-AS1c.2549A>G (p.Asp850Gly)
n.65-72272T>C
c.2333A>G (p.Asp778Gly)
c.2438A>G (p.Asp813Gly)
c.2054A>G (p.Asp685Gly)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193142T>GCA341373422DPYD,DPYD-AS1c.2549A>C (p.Asp850Ala)
n.65-72272T>G
c.2333A>C (p.Asp778Ala)
c.2438A>C (p.Asp813Ala)
c.2054A>C (p.Asp685Ala)
 gnomAD v4
1g.97193142T=CA1182758264DPYD,DPYD-AS1c.2549A= (p.Asp850=)
n.65-72272T=
c.2333A= (p.Asp778=)
c.2438A= (p.Asp813=)
c.2054A= (p.Asp685=)
1g.97193143C>ACA341373423DPYD,DPYD-AS1c.2548G>T (p.Asp850Tyr)
n.65-72271C>A
c.2332G>T (p.Asp778Tyr)
c.2437G>T (p.Asp813Tyr)
c.2053G>T (p.Asp685Tyr)
1g.97193143C=CA1182758265DPYD,DPYD-AS1c.2548G= (p.Asp850=)
n.65-72271C=
c.2332G= (p.Asp778=)
c.2437G= (p.Asp813=)
c.2053G= (p.Asp685=)
1g.97193143C>GCA341373424DPYD,DPYD-AS1c.2548G>C (p.Asp850His)
n.65-72271C>G
c.2332G>C (p.Asp778His)
c.2437G>C (p.Asp813His)
c.2053G>C (p.Asp685His)
1g.97193143C>TCA963010DPYD,DPYD-AS1c.2548G>A (p.Asp850Asn)
n.65-72271C>T
c.2332G>A (p.Asp778Asn)
c.2437G>A (p.Asp813Asn)
c.2053G>A (p.Asp685Asn)
 dbSNP ExAC gnomAD v2 gnomAD v4
1g.97193144C>ACA341373425DPYD,DPYD-AS1c.2547G>T (p.Trp849Cys)
n.65-72270C>A
c.2331G>T (p.Trp777Cys)
c.2436G>T (p.Trp812Cys)
c.2052G>T (p.Trp684Cys)
1g.97193144C>GCA341373426DPYD,DPYD-AS1c.2547G>C (p.Trp849Cys)
n.65-72270C>G
c.2331G>C (p.Trp777Cys)
c.2436G>C (p.Trp812Cys)
c.2052G>C (p.Trp684Cys)
1g.97193144C>TCA341373427DPYD,DPYD-AS1c.2547G>A (p.Trp849Ter)
n.65-72270C>T
c.2331G>A (p.Trp777Ter)
c.2436G>A (p.Trp812Ter)
c.2052G>A (p.Trp684Ter)
 gnomAD v4
1g.97193145C>ACA341373430DPYD,DPYD-AS1c.2546G>T (p.Trp849Leu)
n.65-72269C>A
c.2330G>T (p.Trp777Leu)
c.2435G>T (p.Trp812Leu)
c.2051G>T (p.Trp684Leu)
 COSMIC
1g.97193145C>GCA341373429DPYD,DPYD-AS1c.2546G>C (p.Trp849Ser)
n.65-72269C>G
c.2330G>C (p.Trp777Ser)
c.2435G>C (p.Trp812Ser)
c.2051G>C (p.Trp684Ser)
1g.97193145C>TCA341373428DPYD,DPYD-AS1c.2546G>A (p.Trp849Ter)
n.65-72269C>T
c.2330G>A (p.Trp777Ter)
c.2435G>A (p.Trp812Ter)
c.2051G>A (p.Trp684Ter)
 gnomAD v4
1g.97193146A>CCA341373433DPYD,DPYD-AS1c.2545T>G (p.Trp849Gly)
n.65-72268A>C
c.2329T>G (p.Trp777Gly)
c.2434T>G (p.Trp812Gly)
c.2050T>G (p.Trp684Gly)
1g.97193146A>GCA341373431DPYD,DPYD-AS1c.2545T>C (p.Trp849Arg)
n.65-72268A>G
c.2329T>C (p.Trp777Arg)
c.2434T>C (p.Trp812Arg)
c.2050T>C (p.Trp684Arg)
1g.97193146A>TCA341373432DPYD,DPYD-AS1c.2545T>A (p.Trp849Arg)
n.65-72268A>T
c.2329T>A (p.Trp777Arg)
c.2434T>A (p.Trp812Arg)
c.2050T>A (p.Trp684Arg)
1g.97193147G>ACA419137109DPYD,DPYD-AS1c.2544C>T (p.Asp848=)
n.65-72267G>A
c.2328C>T (p.Asp776=)
c.2433C>T (p.Asp811=)
c.2049C>T (p.Asp683=)
1g.97193147G>CCA341373434DPYD,DPYD-AS1c.2544C>G (p.Asp848Glu)
n.65-72267G>C
c.2328C>G (p.Asp776Glu)
c.2433C>G (p.Asp811Glu)
c.2049C>G (p.Asp683Glu)
1g.97193147G>TCA341373435DPYD,DPYD-AS1c.2544C>A (p.Asp848Glu)
n.65-72267G>T
c.2328C>A (p.Asp776Glu)
c.2433C>A (p.Asp811Glu)
c.2049C>A (p.Asp683Glu)
1g.97193148T>ACA341373436DPYD,DPYD-AS1c.2543A>T (p.Asp848Val)
n.65-72266T>A
c.2327A>T (p.Asp776Val)
c.2432A>T (p.Asp811Val)
c.2048A>T (p.Asp683Val)
1g.97193148T>CCA341373437DPYD,DPYD-AS1c.2543A>G (p.Asp848Gly)
n.65-72266T>C
c.2327A>G (p.Asp776Gly)
c.2432A>G (p.Asp811Gly)
c.2048A>G (p.Asp683Gly)
1g.97193148T>GCA341373438DPYD,DPYD-AS1c.2543A>C (p.Asp848Ala)
n.65-72266T>G
c.2327A>C (p.Asp776Ala)
c.2432A>C (p.Asp811Ala)
c.2048A>C (p.Asp683Ala)
1g.97193149C>ACA341373439DPYD,DPYD-AS1c.2542G>T (p.Asp848Tyr)
n.65-72265C>A
c.2326G>T (p.Asp776Tyr)
c.2431G>T (p.Asp811Tyr)
c.2047G>T (p.Asp683Tyr)
 gnomAD v4
1g.97193149C=CA1182758266DPYD,DPYD-AS1c.2542G= (p.Asp848=)
n.65-72265C=
c.2326G= (p.Asp776=)
c.2431G= (p.Asp811=)
c.2047G= (p.Asp683=)
1g.97193149C>GCA341373440DPYD,DPYD-AS1c.2542G>C (p.Asp848His)
n.65-72265C>G
c.2326G>C (p.Asp776His)
c.2431G>C (p.Asp811His)
c.2047G>C (p.Asp683His)
1g.97193149C>TCA341373441DPYD,DPYD-AS1c.2542G>A (p.Asp848Asn)
n.65-72265C>T
c.2326G>A (p.Asp776Asn)
c.2431G>A (p.Asp811Asn)
c.2047G>A (p.Asp683Asn)
 dbSNP gnomAD v3 gnomAD v4
1g.97193150T>ACA341373442DPYD,DPYD-AS1c.2541A>T (p.Gln847His)
n.65-72264T>A
c.2325A>T (p.Gln775His)
c.2430A>T (p.Gln810His)
c.2046A>T (p.Gln682His)
1g.97193150T>CCA419137110DPYD,DPYD-AS1c.2541A>G (p.Gln847=)
n.65-72264T>C
c.2325A>G (p.Gln775=)
c.2430A>G (p.Gln810=)
c.2046A>G (p.Gln682=)
1g.97193150T>GCA341373443DPYD,DPYD-AS1c.2541A>C (p.Gln847His)
n.65-72264T>G
c.2325A>C (p.Gln775His)
c.2430A>C (p.Gln810His)
c.2046A>C (p.Gln682His)
1g.97193151T>ACA341373446DPYD,DPYD-AS1c.2540A>T (p.Gln847Leu)
n.65-72263T>A
c.2324A>T (p.Gln775Leu)
c.2429A>T (p.Gln810Leu)
c.2045A>T (p.Gln682Leu)
1g.97193151T>CCA341373445DPYD,DPYD-AS1c.2540A>G (p.Gln847Arg)
n.65-72263T>C
c.2324A>G (p.Gln775Arg)
c.2429A>G (p.Gln810Arg)
c.2045A>G (p.Gln682Arg)
1g.97193151T>GCA341373444DPYD,DPYD-AS1c.2540A>C (p.Gln847Pro)
n.65-72263T>G
c.2324A>C (p.Gln775Pro)
c.2429A>C (p.Gln810Pro)
c.2045A>C (p.Gln682Pro)
1g.97193152G>ACA341373447DPYD,DPYD-AS1c.2539C>T (p.Gln847Ter)
n.65-72262G>A
c.2323C>T (p.Gln775Ter)
c.2428C>T (p.Gln810Ter)
c.2044C>T (p.Gln682Ter)
1g.97193152G>CCA341373448DPYD,DPYD-AS1c.2539C>G (p.Gln847Glu)
n.65-72262G>C
c.2323C>G (p.Gln775Glu)
c.2428C>G (p.Gln810Glu)
c.2044C>G (p.Gln682Glu)
1g.97193152G>TCA341373449DPYD,DPYD-AS1c.2539C>A (p.Gln847Lys)
n.65-72262G>T
c.2323C>A (p.Gln775Lys)
c.2428C>A (p.Gln810Lys)
c.2044C>A (p.Gln682Lys)
1g.97193153T>ACA419137111DPYD,DPYD-AS1c.2538A>T (p.Leu846=)
n.65-72261T>A
c.2322A>T (p.Leu774=)
c.2427A>T (p.Leu809=)
c.2043A>T (p.Leu681=)
1g.97193153T>CCA419137113DPYD,DPYD-AS1c.2538A>G (p.Leu846=)
n.65-72261T>C
c.2322A>G (p.Leu774=)
c.2427A>G (p.Leu809=)
c.2043A>G (p.Leu681=)
 dbSNP gnomAD v2 gnomAD v4
1g.97193153T>GCA419137115DPYD,DPYD-AS1c.2538A>C (p.Leu846=)
n.65-72261T>G
c.2322A>C (p.Leu774=)
c.2427A>C (p.Leu809=)
c.2043A>C (p.Leu681=)
1g.97193153T=CA1182758267DPYD,DPYD-AS1c.2538A= (p.Leu846=)
n.65-72261T=
c.2322A= (p.Leu774=)
c.2427A= (p.Leu809=)
c.2043A= (p.Leu681=)
1g.97193154A>CCA341373450DPYD,DPYD-AS1c.2537T>G (p.Leu846Arg)
n.65-72260A>C
c.2321T>G (p.Leu774Arg)
c.2426T>G (p.Leu809Arg)
c.2042T>G (p.Leu681Arg)
1g.97193154A>GCA341373451DPYD,DPYD-AS1c.2537T>C (p.Leu846Pro)
n.65-72260A>G
c.2321T>C (p.Leu774Pro)
c.2426T>C (p.Leu809Pro)
c.2042T>C (p.Leu681Pro)
1g.97193154A>TCA341373452DPYD,DPYD-AS1c.2537T>A (p.Leu846Gln)
n.65-72260A>T
c.2321T>A (p.Leu774Gln)
c.2426T>A (p.Leu809Gln)
c.2042T>A (p.Leu681Gln)
1g.97193155G>ACA419137116DPYD,DPYD-AS1c.2536C>T (p.Leu846=)
n.65-72259G>A
c.2320C>T (p.Leu774=)
c.2425C>T (p.Leu809=)
c.2041C>T (p.Leu681=)
 gnomAD v4
1g.97193155G>CCA341373453DPYD,DPYD-AS1c.2536C>G (p.Leu846Val)
n.65-72259G>C
c.2320C>G (p.Leu774Val)
c.2425C>G (p.Leu809Val)
c.2041C>G (p.Leu681Val)
1g.97193155G>TCA341373454DPYD,DPYD-AS1c.2536C>A (p.Leu846Ile)
n.65-72259G>T
c.2320C>A (p.Leu774Ile)
c.2425C>A (p.Leu809Ile)
c.2041C>A (p.Leu681Ile)
1g.97193156T>ACA341373455DPYD,DPYD-AS1c.2535A>T (p.Glu845Asp)
n.65-72258T>A
c.2319A>T (p.Glu773Asp)
c.2424A>T (p.Glu808Asp)
c.2040A>T (p.Glu680Asp)
 gnomAD v4
1g.97193156T>CCA419137117DPYD,DPYD-AS1c.2535A>G (p.Glu845=)
n.65-72258T>C
c.2319A>G (p.Glu773=)
c.2424A>G (p.Glu808=)
c.2040A>G (p.Glu680=)
 gnomAD v4
1g.97193156T>GCA341373456DPYD,DPYD-AS1c.2535A>C (p.Glu845Asp)
n.65-72258T>G
c.2319A>C (p.Glu773Asp)
c.2424A>C (p.Glu808Asp)
c.2040A>C (p.Glu680Asp)
1g.97193157T>ACA341373457DPYD,DPYD-AS1c.2534A>T (p.Glu845Val)
n.65-72257T>A
c.2318A>T (p.Glu773Val)
c.2423A>T (p.Glu808Val)
c.2039A>T (p.Glu680Val)
1g.97193157T>CCA341373458DPYD,DPYD-AS1c.2534A>G (p.Glu845Gly)
n.65-72257T>C
c.2318A>G (p.Glu773Gly)
c.2423A>G (p.Glu808Gly)
c.2039A>G (p.Glu680Gly)
1g.97193157T>GCA341373459DPYD,DPYD-AS1c.2534A>C (p.Glu845Ala)
n.65-72257T>G
c.2318A>C (p.Glu773Ala)
c.2423A>C (p.Glu808Ala)
c.2039A>C (p.Glu680Ala)
 gnomAD v4
1g.97193158C>ACA341373461DPYD,DPYD-AS1c.2533G>T (p.Glu845Ter)
n.65-72256C>A
c.2317G>T (p.Glu773Ter)
c.2422G>T (p.Glu808Ter)
c.2038G>T (p.Glu680Ter)
1g.97193158C=CA1182758268DPYD,DPYD-AS1c.2533G= (p.Glu845=)
n.65-72256C=
c.2317G= (p.Glu773=)
c.2422G= (p.Glu808=)
c.2038G= (p.Glu680=)
1g.97193158C>GCA341373462DPYD,DPYD-AS1c.2533G>C (p.Glu845Gln)
n.65-72256C>G
c.2317G>C (p.Glu773Gln)
c.2422G>C (p.Glu808Gln)
c.2038G>C (p.Glu680Gln)
1g.97193158C>TCA341373460DPYD,DPYD-AS1c.2533G>A (p.Glu845Lys)
n.65-72256C>T
c.2317G>A (p.Glu773Lys)
c.2422G>A (p.Glu808Lys)
c.2038G>A (p.Glu680Lys)
 dbSNP gnomAD v4
1g.97193159T>ACA341373463DPYD,DPYD-AS1c.2532A>T (p.Glu844Asp)
n.65-72255T>A
c.2316A>T (p.Glu772Asp)
c.2421A>T (p.Glu807Asp)
c.2037A>T (p.Glu679Asp)
1g.97193159T>CCA228084DPYD,DPYD-AS1c.2532A>G (p.Glu844=)
n.65-72255T>C
c.2316A>G (p.Glu772=)
c.2421A>G (p.Glu807=)
c.2037A>G (p.Glu679=)
 ClinVar dbSNP COSMIC
1g.97193159T>GCA963011DPYD,DPYD-AS1c.2532A>C (p.Glu844Asp)
n.65-72255T>G
c.2316A>C (p.Glu772Asp)
c.2421A>C (p.Glu807Asp)
c.2037A>C (p.Glu679Asp)
 dbSNP ExAC gnomAD v2
1g.97193159T=CA1148224414DPYD,DPYD-AS1c.2532A= (p.Glu844=)
n.65-72255T=
c.2316A= (p.Glu772=)
c.2421A= (p.Glu807=)
c.2037A= (p.Glu679=)
1g.97193160T>ACA341373464DPYD,DPYD-AS1c.2531A>T (p.Glu844Val)
n.65-72254T>A
c.2315A>T (p.Glu772Val)
c.2420A>T (p.Glu807Val)
c.2036A>T (p.Glu679Val)
1g.97193160T>CCA341373466DPYD,DPYD-AS1c.2531A>G (p.Glu844Gly)
n.65-72254T>C
c.2315A>G (p.Glu772Gly)
c.2420A>G (p.Glu807Gly)
c.2036A>G (p.Glu679Gly)
1g.97193160T>GCA341373465DPYD,DPYD-AS1c.2531A>C (p.Glu844Ala)
n.65-72254T>G
c.2315A>C (p.Glu772Ala)
c.2420A>C (p.Glu807Ala)
c.2036A>C (p.Glu679Ala)
 gnomAD v4
1g.97193161C>ACA341373467DPYD,DPYD-AS1c.2530G>T (p.Glu844Ter)
n.65-72253C>A
c.2314G>T (p.Glu772Ter)
c.2419G>T (p.Glu807Ter)
c.2035G>T (p.Glu679Ter)
1g.97193161C>GCA341373468DPYD,DPYD-AS1c.2530G>C (p.Glu844Gln)
n.65-72253C>G
c.2314G>C (p.Glu772Gln)
c.2419G>C (p.Glu807Gln)
c.2035G>C (p.Glu679Gln)
1g.97193161C>TCA341373469DPYD,DPYD-AS1c.2530G>A (p.Glu844Lys)
n.65-72253C>T
c.2314G>A (p.Glu772Lys)
c.2419G>A (p.Glu807Lys)
c.2035G>A (p.Glu679Lys)
1g.97193162A>CCA341373470DPYD,DPYD-AS1c.2529T>G (p.Ile843Met)
n.65-72252A>C
c.2313T>G (p.Ile771Met)
c.2418T>G (p.Ile806Met)
c.2034T>G (p.Ile678Met)
1g.97193162A>GCA419137118DPYD,DPYD-AS1c.2529T>C (p.Ile843=)
n.65-72252A>G
c.2313T>C (p.Ile771=)
c.2418T>C (p.Ile806=)
c.2034T>C (p.Ile678=)
1g.97193162A>TCA419137119DPYD,DPYD-AS1c.2529T>A (p.Ile843=)
n.65-72252A>T
c.2313T>A (p.Ile771=)
c.2418T>A (p.Ile806=)
c.2034T>A (p.Ile678=)
1g.97193163A=CA1147577214DPYD,DPYD-AS1c.2528T= (p.Ile843=)
n.65-72251A=
c.2312T= (p.Ile771=)
c.2417T= (p.Ile806=)
c.2033T= (p.Ile678=)
1g.97193163A>CCA341373471DPYD,DPYD-AS1c.2528T>G (p.Ile843Ser)
n.65-72251A>C
c.2312T>G (p.Ile771Ser)
c.2417T>G (p.Ile806Ser)
c.2033T>G (p.Ile678Ser)
1g.97193163A>GCA963012DPYD,DPYD-AS1c.2528T>C (p.Ile843Thr)
n.65-72251A>G
c.2312T>C (p.Ile771Thr)
c.2417T>C (p.Ile806Thr)
c.2033T>C (p.Ile678Thr)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193163A>TCA341373472DPYD,DPYD-AS1c.2528T>A (p.Ile843Asn)
n.65-72251A>T
c.2312T>A (p.Ile771Asn)
c.2417T>A (p.Ile806Asn)
c.2033T>A (p.Ile678Asn)
 gnomAD v4
1g.97193164T>ACA341373473DPYD,DPYD-AS1c.2527A>T (p.Ile843Phe)
n.65-72250T>A
c.2311A>T (p.Ile771Phe)
c.2416A>T (p.Ile806Phe)
c.2032A>T (p.Ile678Phe)
1g.97193164T>CCA963013DPYD,DPYD-AS1c.2527A>G (p.Ile843Val)
n.65-72250T>C
c.2311A>G (p.Ile771Val)
c.2416A>G (p.Ile806Val)
c.2032A>G (p.Ile678Val)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193164T>GCA341373474DPYD,DPYD-AS1c.2527A>C (p.Ile843Leu)
n.65-72250T>G
c.2311A>C (p.Ile771Leu)
c.2416A>C (p.Ile806Leu)
c.2032A>C (p.Ile678Leu)
1g.97193164T=CA1143836488DPYD,DPYD-AS1c.2527A= (p.Ile843=)
n.65-72250T=
c.2311A= (p.Ile771=)
c.2416A= (p.Ile806=)
c.2032A= (p.Ile678=)
1g.97193165G>ACA419137120DPYD,DPYD-AS1c.2526C>T (p.Ser842=)
n.65-72249G>A
c.2310C>T (p.Ser770=)
c.2415C>T (p.Ser805=)
c.2031C>T (p.Ser677=)
1g.97193165G>CCA341373476DPYD,DPYD-AS1c.2526C>G (p.Ser842Arg)
n.65-72249G>C
c.2310C>G (p.Ser770Arg)
c.2415C>G (p.Ser805Arg)
c.2031C>G (p.Ser677Arg)
1g.97193165G>TCA341373475DPYD,DPYD-AS1c.2526C>A (p.Ser842Arg)
n.65-72249G>T
c.2310C>A (p.Ser770Arg)
c.2415C>A (p.Ser805Arg)
c.2031C>A (p.Ser677Arg)
1g.97193166C>ACA10610857DPYD,DPYD-AS1c.2525G>T (p.Ser842Ile)
n.65-72248C>A
c.2309G>T (p.Ser770Ile)
c.2414G>T (p.Ser805Ile)
c.2030G>T (p.Ser677Ile)
 ClinVar dbSNP
1g.97193166C=CA1182758269DPYD,DPYD-AS1c.2525G= (p.Ser842=)
n.65-72248C=
c.2309G= (p.Ser770=)
c.2414G= (p.Ser805=)
c.2030G= (p.Ser677=)
1g.97193166C>GCA341373477DPYD,DPYD-AS1c.2525G>C (p.Ser842Thr)
n.65-72248C>G
c.2309G>C (p.Ser770Thr)
c.2414G>C (p.Ser805Thr)
c.2030G>C (p.Ser677Thr)
1g.97193166C>TCA341373478DPYD,DPYD-AS1c.2525G>A (p.Ser842Asn)
n.65-72248C>T
c.2309G>A (p.Ser770Asn)
c.2414G>A (p.Ser805Asn)
c.2030G>A (p.Ser677Asn)
 gnomAD v4
1g.97193167T>ACA341373479DPYD,DPYD-AS1c.2524A>T (p.Ser842Cys)
n.65-72247T>A
c.2308A>T (p.Ser770Cys)
c.2413A>T (p.Ser805Cys)
c.2029A>T (p.Ser677Cys)
1g.97193167T>CCA341373480DPYD,DPYD-AS1c.2524A>G (p.Ser842Gly)
n.65-72247T>C
c.2308A>G (p.Ser770Gly)
c.2413A>G (p.Ser805Gly)
c.2029A>G (p.Ser677Gly)
1g.97193167T>GCA341373481DPYD,DPYD-AS1c.2524A>C (p.Ser842Arg)
n.65-72247T>G
c.2308A>C (p.Ser770Arg)
c.2413A>C (p.Ser805Arg)
c.2029A>C (p.Ser677Arg)
1g.97193168T>ACA341373482DPYD,DPYD-AS1c.2523A>T (p.Lys841Asn)
n.65-72246T>A
c.2307A>T (p.Lys769Asn)
c.2412A>T (p.Lys804Asn)
c.2028A>T (p.Lys676Asn)
1g.97193168T>CCA419137121DPYD,DPYD-AS1c.2523A>G (p.Lys841=)
n.65-72246T>C
c.2307A>G (p.Lys769=)
c.2412A>G (p.Lys804=)
c.2028A>G (p.Lys676=)
1g.97193168T>GCA341373483DPYD,DPYD-AS1c.2523A>C (p.Lys841Asn)
n.65-72246T>G
c.2307A>C (p.Lys769Asn)
c.2412A>C (p.Lys804Asn)
c.2028A>C (p.Lys676Asn)
1g.97193169T>ACA341373484DPYD,DPYD-AS1c.2522A>T (p.Lys841Ile)
n.65-72245T>A
c.2306A>T (p.Lys769Ile)
c.2411A>T (p.Lys804Ile)
c.2027A>T (p.Lys676Ile)
 COSMIC
1g.97193169T>CCA341373485DPYD,DPYD-AS1c.2522A>G (p.Lys841Arg)
n.65-72245T>C
c.2306A>G (p.Lys769Arg)
c.2411A>G (p.Lys804Arg)
c.2027A>G (p.Lys676Arg)
1g.97193169T>GCA341373486DPYD,DPYD-AS1c.2522A>C (p.Lys841Thr)
n.65-72245T>G
c.2306A>C (p.Lys769Thr)
c.2411A>C (p.Lys804Thr)
c.2027A>C (p.Lys676Thr)
1g.97193170T>ACA341373488DPYD,DPYD-AS1c.2521A>T (p.Lys841Ter)
n.65-72244T>A
c.2305A>T (p.Lys769Ter)
c.2410A>T (p.Lys804Ter)
c.2026A>T (p.Lys676Ter)
1g.97193170T>CCA341373489DPYD,DPYD-AS1c.2521A>G (p.Lys841Glu)
n.65-72244T>C
c.2305A>G (p.Lys769Glu)
c.2410A>G (p.Lys804Glu)
c.2026A>G (p.Lys676Glu)
1g.97193170T>GCA341373487DPYD,DPYD-AS1c.2521A>C (p.Lys841Gln)
n.65-72244T>G
c.2305A>C (p.Lys769Gln)
c.2410A>C (p.Lys804Gln)
c.2026A>C (p.Lys676Gln)
1g.97193171C>ACA419137122DPYD,DPYD-AS1c.2520G>T (p.Leu840=)
n.65-72243C>A
c.2304G>T (p.Leu768=)
c.2409G>T (p.Leu803=)
c.2025G>T (p.Leu675=)
1g.97193171C>GCA419137123DPYD,DPYD-AS1c.2520G>C (p.Leu840=)
n.65-72243C>G
c.2304G>C (p.Leu768=)
c.2409G>C (p.Leu803=)
c.2025G>C (p.Leu675=)
1g.97193171C>TCA419137124DPYD,DPYD-AS1c.2520G>A (p.Leu840=)
n.65-72243C>T
c.2304G>A (p.Leu768=)
c.2409G>A (p.Leu803=)
c.2025G>A (p.Leu675=)
 COSMIC
1g.97193172A>CCA341373490DPYD,DPYD-AS1c.2519T>G (p.Leu840Arg)
n.65-72242A>C
c.2303T>G (p.Leu768Arg)
c.2408T>G (p.Leu803Arg)
c.2024T>G (p.Leu675Arg)
1g.97193172A>GCA341373491DPYD,DPYD-AS1c.2519T>C (p.Leu840Pro)
n.65-72242A>G
c.2303T>C (p.Leu768Pro)
c.2408T>C (p.Leu803Pro)
c.2024T>C (p.Leu675Pro)
1g.97193172A>TCA341373492DPYD,DPYD-AS1c.2519T>A (p.Leu840Gln)
n.65-72242A>T
c.2303T>A (p.Leu768Gln)
c.2408T>A (p.Leu803Gln)
c.2024T>A (p.Leu675Gln)
1g.97193173G>ACA419137125DPYD,DPYD-AS1c.2518C>T (p.Leu840=)
n.65-72241G>A
c.2302C>T (p.Leu768=)
c.2407C>T (p.Leu803=)
c.2023C>T (p.Leu675=)
1g.97193173G>CCA341373493DPYD,DPYD-AS1c.2518C>G (p.Leu840Val)
n.65-72241G>C
c.2302C>G (p.Leu768Val)
c.2407C>G (p.Leu803Val)
c.2023C>G (p.Leu675Val)
 gnomAD v4
1g.97193173G>TCA341373494DPYD,DPYD-AS1c.2518C>A (p.Leu840Met)
n.65-72241G>T
c.2302C>A (p.Leu768Met)
c.2407C>A (p.Leu803Met)
c.2023C>A (p.Leu675Met)
1g.97193174A>CCA341373496DPYD,DPYD-AS1c.2517T>G (p.Tyr839Ter)
n.65-72240A>C
c.2301T>G (p.Tyr767Ter)
c.2406T>G (p.Tyr802Ter)
c.2022T>G (p.Tyr674Ter)
1g.97193174A>GCA419137127DPYD,DPYD-AS1c.2517T>C (p.Tyr839=)
n.65-72240A>G
c.2301T>C (p.Tyr767=)
c.2406T>C (p.Tyr802=)
c.2022T>C (p.Tyr674=)
1g.97193174A>TCA341373495DPYD,DPYD-AS1c.2517T>A (p.Tyr839Ter)
n.65-72240A>T
c.2301T>A (p.Tyr767Ter)
c.2406T>A (p.Tyr802Ter)
c.2022T>A (p.Tyr674Ter)
1g.97193175T>ACA341373497DPYD,DPYD-AS1c.2516A>T (p.Tyr839Phe)
n.65-72239T>A
c.2300A>T (p.Tyr767Phe)
c.2405A>T (p.Tyr802Phe)
c.2021A>T (p.Tyr674Phe)
 COSMIC
1g.97193175T>CCA341373498DPYD,DPYD-AS1c.2516A>G (p.Tyr839Cys)
n.65-72239T>C
c.2300A>G (p.Tyr767Cys)
c.2405A>G (p.Tyr802Cys)
c.2021A>G (p.Tyr674Cys)
1g.97193175T>GCA341373499DPYD,DPYD-AS1c.2516A>C (p.Tyr839Ser)
n.65-72239T>G
c.2300A>C (p.Tyr767Ser)
c.2405A>C (p.Tyr802Ser)
c.2021A>C (p.Tyr674Ser)
1g.97193176A>CCA341373500DPYD,DPYD-AS1c.2515T>G (p.Tyr839Asp)
n.65-72238A>C
c.2299T>G (p.Tyr767Asp)
c.2404T>G (p.Tyr802Asp)
c.2020T>G (p.Tyr674Asp)
1g.97193176A>GCA341373501DPYD,DPYD-AS1c.2515T>C (p.Tyr839His)
n.65-72238A>G
c.2299T>C (p.Tyr767His)
c.2404T>C (p.Tyr802His)
c.2020T>C (p.Tyr674His)
1g.97193176A>TCA341373502DPYD,DPYD-AS1c.2515T>A (p.Tyr839Asn)
n.65-72238A>T
c.2299T>A (p.Tyr767Asn)
c.2404T>A (p.Tyr802Asn)
c.2020T>A (p.Tyr674Asn)
1g.97193177A>CCA419137128DPYD,DPYD-AS1c.2514T>G (p.Leu838=)
n.65-72237A>C
c.2298T>G (p.Leu766=)
c.2403T>G (p.Leu801=)
c.2019T>G (p.Leu673=)
1g.97193177A>GCA419137129DPYD,DPYD-AS1c.2514T>C (p.Leu838=)
n.65-72237A>G
c.2298T>C (p.Leu766=)
c.2403T>C (p.Leu801=)
c.2019T>C (p.Leu673=)
1g.97193177A>TCA419137130DPYD,DPYD-AS1c.2514T>A (p.Leu838=)
n.65-72237A>T
c.2298T>A (p.Leu766=)
c.2403T>A (p.Leu801=)
c.2019T>A (p.Leu673=)
1g.97193178A>CCA341373503DPYD,DPYD-AS1c.2513T>G (p.Leu838Arg)
n.65-72236A>C
c.2297T>G (p.Leu766Arg)
c.2402T>G (p.Leu801Arg)
c.2018T>G (p.Leu673Arg)
1g.97193178A>GCA341373505DPYD,DPYD-AS1c.2513T>C (p.Leu838Pro)
n.65-72236A>G
c.2297T>C (p.Leu766Pro)
c.2402T>C (p.Leu801Pro)
c.2018T>C (p.Leu673Pro)
1g.97193178A>TCA341373504DPYD,DPYD-AS1c.2513T>A (p.Leu838His)
n.65-72236A>T
c.2297T>A (p.Leu766His)
c.2402T>A (p.Leu801His)
c.2018T>A (p.Leu673His)
1g.97193179G>ACA341373506DPYD,DPYD-AS1c.2512C>T (p.Leu838Phe)
n.65-72235G>A
c.2296C>T (p.Leu766Phe)
c.2401C>T (p.Leu801Phe)
c.2017C>T (p.Leu673Phe)
 dbSNP gnomAD v2 gnomAD v4
1g.97193179G>CCA341373507DPYD,DPYD-AS1c.2512C>G (p.Leu838Val)
n.65-72235G>C
c.2296C>G (p.Leu766Val)
c.2401C>G (p.Leu801Val)
c.2017C>G (p.Leu673Val)
1g.97193179G=CA1182758270DPYD,DPYD-AS1c.2512C= (p.Leu838=)
n.65-72235G=
c.2296C= (p.Leu766=)
c.2401C= (p.Leu801=)
c.2017C= (p.Leu673=)
1g.97193179G>TCA341373508DPYD,DPYD-AS1c.2512C>A (p.Leu838Ile)
n.65-72235G>T
c.2296C>A (p.Leu766Ile)
c.2401C>A (p.Leu801Ile)
c.2017C>A (p.Leu673Ile)
1g.97193180C>ACA963014DPYD,DPYD-AS1c.2511G>T (p.Leu837=)
n.65-72234C>A
c.2295G>T (p.Leu765=)
c.2400G>T (p.Leu800=)
c.2016G>T (p.Leu672=)
 dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193180C=CA1182758271DPYD,DPYD-AS1c.2511G= (p.Leu837=)
n.65-72234C=
c.2295G= (p.Leu765=)
c.2400G= (p.Leu800=)
c.2016G= (p.Leu672=)
1g.97193180C>GCA419137144DPYD,DPYD-AS1c.2511G>C (p.Leu837=)
n.65-72234C>G
c.2295G>C (p.Leu765=)
c.2400G>C (p.Leu800=)
c.2016G>C (p.Leu672=)
1g.97193180C>TCA419137147DPYD,DPYD-AS1c.2511G>A (p.Leu837=)
n.65-72234C>T
c.2295G>A (p.Leu765=)
c.2400G>A (p.Leu800=)
c.2016G>A (p.Leu672=)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
1g.97193181A=CA1148731722DPYD,DPYD-AS1c.2510T= (p.Leu837=)
n.65-72233A=
c.2294T= (p.Leu765=)
c.2399T= (p.Leu800=)
c.2015T= (p.Leu672=)
1g.97193181A>CCA341373509DPYD,DPYD-AS1c.2510T>G (p.Leu837Arg)
n.65-72233A>C
c.2294T>G (p.Leu765Arg)
c.2399T>G (p.Leu800Arg)
c.2015T>G (p.Leu672Arg)
1g.97193181A>GCA341373510DPYD,DPYD-AS1c.2510T>C (p.Leu837Pro)
n.65-72233A>G
c.2294T>C (p.Leu765Pro)
c.2399T>C (p.Leu800Pro)
c.2015T>C (p.Leu672Pro)
 gnomAD v4
1g.97193181A>TCA963015DPYD,DPYD-AS1c.2510T>A (p.Leu837Gln)
n.65-72233A>T
c.2294T>A (p.Leu765Gln)
c.2399T>A (p.Leu800Gln)
c.2015T>A (p.Leu672Gln)
 dbSNP ExAC gnomAD v2 gnomAD v4
1g.97193182G>ACA419137157DPYD,DPYD-AS1c.2509C>T (p.Leu837=)
n.65-72232G>A
c.2293C>T (p.Leu765=)
c.2398C>T (p.Leu800=)
c.2014C>T (p.Leu672=)
 dbSNP
1g.97193182G>CCA341373511DPYD,DPYD-AS1c.2509C>G (p.Leu837Val)
n.65-72232G>C
c.2293C>G (p.Leu765Val)
c.2398C>G (p.Leu800Val)
c.2014C>G (p.Leu672Val)
1g.97193182G=CA1182758273DPYD,DPYD-AS1c.2509C= (p.Leu837=)
n.65-72232G=
c.2293C= (p.Leu765=)
c.2398C= (p.Leu800=)
c.2014C= (p.Leu672=)
1g.97193182G>TCA341373512DPYD,DPYD-AS1c.2509C>A (p.Leu837Met)
n.65-72232G>T
c.2293C>A (p.Leu765Met)
c.2398C>A (p.Leu800Met)
c.2014C>A (p.Leu672Met)
1g.97193184dupCA1182758272DPYD,DPYD-AS1c.2509dup (p.Leu837ProfsTer8)
n.65-72230dup
c.2293dup (p.Leu765ProfsTer8)
c.2398dup (p.Leu800ProfsTer8)
c.2014dup (p.Leu672ProfsTer8)
 dbSNP gnomAD v4
1g.97193183G>ACA419137163DPYD,DPYD-AS1c.2508C>T (p.Ala836=)
n.65-72231G>A
c.2292C>T (p.Ala764=)
c.2397C>T (p.Ala799=)
c.2013C>T (p.Ala671=)
 dbSNP gnomAD v2 gnomAD v4
1g.97193183G>CCA419137167DPYD,DPYD-AS1c.2508C>G (p.Ala836=)
n.65-72231G>C
c.2292C>G (p.Ala764=)
c.2397C>G (p.Ala799=)
c.2013C>G (p.Ala671=)
1g.97193183G=CA1182758274DPYD,DPYD-AS1c.2508C= (p.Ala836=)
n.65-72231G=
c.2292C= (p.Ala764=)
c.2397C= (p.Ala799=)
c.2013C= (p.Ala671=)
1g.97193183G>TCA419137165DPYD,DPYD-AS1c.2508C>A (p.Ala836=)
n.65-72231G>T
c.2292C>A (p.Ala764=)
c.2397C>A (p.Ala799=)
c.2013C>A (p.Ala671=)
 dbSNP gnomAD v2 gnomAD v4
1g.97193184G>ACA341373513DPYD,DPYD-AS1c.2507C>T (p.Ala836Val)
n.65-72230G>A
c.2291C>T (p.Ala764Val)
c.2396C>T (p.Ala799Val)
c.2012C>T (p.Ala671Val)
1g.97193184G>CCA341373514DPYD,DPYD-AS1c.2507C>G (p.Ala836Gly)
n.65-72230G>C
c.2291C>G (p.Ala764Gly)
c.2396C>G (p.Ala799Gly)
c.2012C>G (p.Ala671Gly)
1g.97193184G>TCA341373515DPYD,DPYD-AS1c.2507C>A (p.Ala836Asp)
n.65-72230G>T
c.2291C>A (p.Ala764Asp)
c.2396C>A (p.Ala799Asp)
c.2012C>A (p.Ala671Asp)
1g.97193185C>ACA341373517DPYD,DPYD-AS1c.2506G>T (p.Ala836Ser)
n.65-72229C>A
c.2290G>T (p.Ala764Ser)
c.2395G>T (p.Ala799Ser)
c.2011G>T (p.Ala671Ser)
1g.97193185C>GCA341373518DPYD,DPYD-AS1c.2506G>C (p.Ala836Pro)
n.65-72229C>G
c.2290G>C (p.Ala764Pro)
c.2395G>C (p.Ala799Pro)
c.2011G>C (p.Ala671Pro)
1g.97193185C>TCA341373516DPYD,DPYD-AS1c.2506G>A (p.Ala836Thr)
n.65-72229C>T
c.2290G>A (p.Ala764Thr)
c.2395G>A (p.Ala799Thr)
c.2011G>A (p.Ala671Thr)
1g.97193186T>ACA341373520DPYD,DPYD-AS1c.2505A>T (p.Lys835Asn)
n.65-72228T>A
c.2289A>T (p.Lys763Asn)
c.2394A>T (p.Lys798Asn)
c.2010A>T (p.Lys670Asn)
1g.97193186T>CCA419137182DPYD,DPYD-AS1c.2505A>G (p.Lys835=)
n.65-72228T>C
c.2289A>G (p.Lys763=)
c.2394A>G (p.Lys798=)
c.2010A>G (p.Lys670=)
1g.97193186T>GCA341373519DPYD,DPYD-AS1c.2505A>C (p.Lys835Asn)
n.65-72228T>G
c.2289A>C (p.Lys763Asn)
c.2394A>C (p.Lys798Asn)
c.2010A>C (p.Lys670Asn)
1g.97193187T>ACA341373521DPYD,DPYD-AS1c.2504A>T (p.Lys835Ile)
n.65-72227T>A
c.2288A>T (p.Lys763Ile)
c.2393A>T (p.Lys798Ile)
c.2009A>T (p.Lys670Ile)
1g.97193187T>CCA341373522DPYD,DPYD-AS1c.2504A>G (p.Lys835Arg)
n.65-72227T>C
c.2288A>G (p.Lys763Arg)
c.2393A>G (p.Lys798Arg)
c.2009A>G (p.Lys670Arg)
1g.97193187T>GCA341373523DPYD,DPYD-AS1c.2504A>C (p.Lys835Thr)
n.65-72227T>G
c.2288A>C (p.Lys763Thr)
c.2393A>C (p.Lys798Thr)
c.2009A>C (p.Lys670Thr)
1g.97193188T>ACA341373524DPYD,DPYD-AS1c.2503A>T (p.Lys835Ter)
n.65-72226T>A
c.2287A>T (p.Lys763Ter)
c.2392A>T (p.Lys798Ter)
c.2008A>T (p.Lys670Ter)
1g.97193188T>CCA341373525DPYD,DPYD-AS1c.2503A>G (p.Lys835Glu)
n.65-72226T>C
c.2287A>G (p.Lys763Glu)
c.2392A>G (p.Lys798Glu)
c.2008A>G (p.Lys670Glu)
1g.97193188T>GCA341373526DPYD,DPYD-AS1c.2503A>C (p.Lys835Gln)
n.65-72226T>G
c.2287A>C (p.Lys763Gln)
c.2392A>C (p.Lys798Gln)
c.2008A>C (p.Lys670Gln)
1g.97193189G>ACA963016DPYD,DPYD-AS1c.2502C>T (p.Leu834=)
n.65-72225G>A
c.2286C>T (p.Leu762=)
c.2391C>T (p.Leu797=)
c.2007C>T (p.Leu669=)
 dbSNP ExAC gnomAD v2 gnomAD v4
1g.97193189G>CCA419137199DPYD,DPYD-AS1c.2502C>G (p.Leu834=)
n.65-72225G>C
c.2286C>G (p.Leu762=)
c.2391C>G (p.Leu797=)
c.2007C>G (p.Leu669=)
 dbSNP gnomAD v3 gnomAD v4
1g.97193189G=CA1182758275DPYD,DPYD-AS1c.2502C= (p.Leu834=)
n.65-72225G=
c.2286C= (p.Leu762=)
c.2391C= (p.Leu797=)
c.2007C= (p.Leu669=)
1g.97193189G>TCA419137205DPYD,DPYD-AS1c.2502C>A (p.Leu834=)
n.65-72225G>T
c.2286C>A (p.Leu762=)
c.2391C>A (p.Leu797=)
c.2007C>A (p.Leu669=)
1g.97193190A>CCA341373527DPYD,DPYD-AS1c.2501T>G (p.Leu834Arg)
n.65-72224A>C
c.2285T>G (p.Leu762Arg)
c.2390T>G (p.Leu797Arg)
c.2006T>G (p.Leu669Arg)
 gnomAD v4
1g.97193190A>GCA341373528DPYD,DPYD-AS1c.2501T>C (p.Leu834Pro)
n.65-72224A>G
c.2285T>C (p.Leu762Pro)
c.2390T>C (p.Leu797Pro)
c.2006T>C (p.Leu669Pro)
1g.97193190A>TCA341373529DPYD,DPYD-AS1c.2501T>A (p.Leu834His)
n.65-72224A>T
c.2285T>A (p.Leu762His)
c.2390T>A (p.Leu797His)
c.2006T>A (p.Leu669His)
1g.97193191G>ACA341373530DPYD,DPYD-AS1c.2500C>T (p.Leu834Phe)
n.65-72223G>A
c.2284C>T (p.Leu762Phe)
c.2389C>T (p.Leu797Phe)
c.2005C>T (p.Leu669Phe)
1g.97193191G>CCA341373531DPYD,DPYD-AS1c.2500C>G (p.Leu834Val)
n.65-72223G>C
c.2284C>G (p.Leu762Val)
c.2389C>G (p.Leu797Val)
c.2005C>G (p.Leu669Val)
1g.97193191G>TCA341373532DPYD,DPYD-AS1c.2500C>A (p.Leu834Ile)
n.65-72223G>T
c.2284C>A (p.Leu762Ile)
c.2389C>A (p.Leu797Ile)
c.2005C>A (p.Leu669Ile)
1g.97193192G>ACA419137218DPYD,DPYD-AS1c.2499C>T (p.Gly833=)
n.65-72222G>A
c.2283C>T (p.Gly761=)
c.2388C>T (p.Gly796=)
c.2004C>T (p.Gly668=)
1g.97193192G>CCA419137220DPYD,DPYD-AS1c.2499C>G (p.Gly833=)
n.65-72222G>C
c.2283C>G (p.Gly761=)
c.2388C>G (p.Gly796=)
c.2004C>G (p.Gly668=)
1g.97193192G>TCA419137222DPYD,DPYD-AS1c.2499C>A (p.Gly833=)
n.65-72222G>T
c.2283C>A (p.Gly761=)
c.2388C>A (p.Gly796=)
c.2004C>A (p.Gly668=)
1g.97193193C>ACA341373533DPYD,DPYD-AS1c.2498G>T (p.Gly833Val)
n.65-72221C>A
c.2282G>T (p.Gly761Val)
c.2387G>T (p.Gly796Val)
c.2003G>T (p.Gly668Val)
1g.97193193C>GCA341373535DPYD,DPYD-AS1c.2498G>C (p.Gly833Ala)
n.65-72221C>G
c.2282G>C (p.Gly761Ala)
c.2387G>C (p.Gly796Ala)
c.2003G>C (p.Gly668Ala)
1g.97193193C>TCA341373534DPYD,DPYD-AS1c.2498G>A (p.Gly833Asp)
n.65-72221C>T
c.2282G>A (p.Gly761Asp)
c.2387G>A (p.Gly796Asp)
c.2003G>A (p.Gly668Asp)
 gnomAD v4
1g.97193194C>ACA341373536DPYD,DPYD-AS1c.2497G>T (p.Gly833Cys)
n.65-72220C>A
c.2281G>T (p.Gly761Cys)
c.2386G>T (p.Gly796Cys)
c.2002G>T (p.Gly668Cys)
 gnomAD v4
1g.97193194C>GCA341373537DPYD,DPYD-AS1c.2497G>C (p.Gly833Arg)
n.65-72220C>G
c.2281G>C (p.Gly761Arg)
c.2386G>C (p.Gly796Arg)
c.2002G>C (p.Gly668Arg)
1g.97193194C>TCA341373538DPYD,DPYD-AS1c.2497G>A (p.Gly833Ser)
n.65-72220C>T
c.2281G>A (p.Gly761Ser)
c.2386G>A (p.Gly796Ser)
c.2002G>A (p.Gly668Ser)
1g.97193195A>CCA419137241DPYD,DPYD-AS1c.2496T>G (p.Thr832=)
n.65-72219A>C
c.2280T>G (p.Thr760=)
c.2385T>G (p.Thr795=)
c.2001T>G (p.Thr667=)
1g.97193195A>GCA419137245DPYD,DPYD-AS1c.2496T>C (p.Thr832=)
n.65-72219A>G
c.2280T>C (p.Thr760=)
c.2385T>C (p.Thr795=)
c.2001T>C (p.Thr667=)
1g.97193195A>TCA419137243DPYD,DPYD-AS1c.2496T>A (p.Thr832=)
n.65-72219A>T
c.2280T>A (p.Thr760=)
c.2385T>A (p.Thr795=)
c.2001T>A (p.Thr667=)
1g.97193196G>ACA341373539DPYD,DPYD-AS1c.2495C>T (p.Thr832Ile)
n.65-72218G>A
c.2279C>T (p.Thr760Ile)
c.2384C>T (p.Thr795Ile)
c.2000C>T (p.Thr667Ile)
 COSMIC
1g.97193196G>CCA341373540DPYD,DPYD-AS1c.2495C>G (p.Thr832Ser)
n.65-72218G>C
c.2279C>G (p.Thr760Ser)
c.2384C>G (p.Thr795Ser)
c.2000C>G (p.Thr667Ser)
1g.97193196G>TCA341373541DPYD,DPYD-AS1c.2495C>A (p.Thr832Asn)
n.65-72218G>T
c.2279C>A (p.Thr760Asn)
c.2384C>A (p.Thr795Asn)
c.2000C>A (p.Thr667Asn)
 COSMIC
1g.97193197T>ACA341373542DPYD,DPYD-AS1c.2494A>T (p.Thr832Ser)
n.65-72217T>A
c.2278A>T (p.Thr760Ser)
c.2383A>T (p.Thr795Ser)
c.1999A>T (p.Thr667Ser)
1g.97193197T>CCA341373543DPYD,DPYD-AS1c.2494A>G (p.Thr832Ala)
n.65-72217T>C
c.2278A>G (p.Thr760Ala)
c.2383A>G (p.Thr795Ala)
c.1999A>G (p.Thr667Ala)
 ClinVar dbSNP gnomAD v2 gnomAD v4
1g.97193197T>GCA341373544DPYD,DPYD-AS1c.2494A>C (p.Thr832Pro)
n.65-72217T>G
c.2278A>C (p.Thr760Pro)
c.2383A>C (p.Thr795Pro)
c.1999A>C (p.Thr667Pro)
 gnomAD v4
1g.97193197T=CA1182758276DPYD,DPYD-AS1c.2494A= (p.Thr832=)
n.65-72217T=
c.2278A= (p.Thr760=)
c.2383A= (p.Thr795=)
c.1999A= (p.Thr667=)
1g.97193198G>ACA419137255DPYD,DPYD-AS1c.2493C>T (p.Cys831=)
n.65-72216G>A
c.2277C>T (p.Cys759=)
c.2382C>T (p.Cys794=)
c.1998C>T (p.Cys666=)
1g.97193198G>CCA341373545DPYD,DPYD-AS1c.2493C>G (p.Cys831Trp)
n.65-72216G>C
c.2277C>G (p.Cys759Trp)
c.2382C>G (p.Cys794Trp)
c.1998C>G (p.Cys666Trp)
1g.97193198G>TCA341373546DPYD,DPYD-AS1c.2493C>A (p.Cys831Ter)
n.65-72216G>T
c.2277C>A (p.Cys759Ter)
c.2382C>A (p.Cys794Ter)
c.1998C>A (p.Cys666Ter)
1g.97193199C>ACA963017DPYD,DPYD-AS1c.2492G>T (p.Cys831Phe)
n.65-72215C>A
c.2276G>T (p.Cys759Phe)
c.2381G>T (p.Cys794Phe)
c.1997G>T (p.Cys666Phe)
 dbSNP ExAC gnomAD v2 gnomAD v4
1g.97193199C=CA1182758277DPYD,DPYD-AS1c.2492G= (p.Cys831=)
n.65-72215C=
c.2276G= (p.Cys759=)
c.2381G= (p.Cys794=)
c.1997G= (p.Cys666=)
1g.97193199C>GCA341373548DPYD,DPYD-AS1c.2492G>C (p.Cys831Ser)
n.65-72215C>G
c.2276G>C (p.Cys759Ser)
c.2381G>C (p.Cys794Ser)
c.1997G>C (p.Cys666Ser)
1g.97193199C>TCA341373547DPYD,DPYD-AS1c.2492G>A (p.Cys831Tyr)
n.65-72215C>T
c.2276G>A (p.Cys759Tyr)
c.2381G>A (p.Cys794Tyr)
c.1997G>A (p.Cys666Tyr)
1g.97193200A>CCA341373549DPYD,DPYD-AS1c.2491T>G (p.Cys831Gly)
n.65-72214A>C
c.2275T>G (p.Cys759Gly)
c.2380T>G (p.Cys794Gly)
c.1996T>G (p.Cys666Gly)
 gnomAD v4
1g.97193200A>GCA341373550DPYD,DPYD-AS1c.2491T>C (p.Cys831Arg)
n.65-72214A>G
c.2275T>C (p.Cys759Arg)
c.2380T>C (p.Cys794Arg)
c.1996T>C (p.Cys666Arg)
1g.97193200A>TCA341373551DPYD,DPYD-AS1c.2491T>A (p.Cys831Ser)
n.65-72214A>T
c.2275T>A (p.Cys759Ser)
c.2380T>A (p.Cys794Ser)
c.1996T>A (p.Cys666Ser)
 gnomAD v4
1g.97193203_97193205delCA2744694192DPYD,DPYD-AS1c.2489_2491del (p.Tyr830del)
n.65-72211_65-72209del
c.2273_2275del (p.Tyr758del)
c.2378_2380del (p.Tyr793del)
c.1994_1996del (p.Tyr665del)
1g.97193201G>ACA419137272DPYD,DPYD-AS1c.2490C>T (p.Tyr830=)
n.65-72213G>A
c.2274C>T (p.Tyr758=)
c.2379C>T (p.Tyr793=)
c.1995C>T (p.Tyr665=)
 dbSNP gnomAD v2 gnomAD v4
1g.97193201G>CCA341373552DPYD,DPYD-AS1c.2490C>G (p.Tyr830Ter)
n.65-72213G>C
c.2274C>G (p.Tyr758Ter)
c.2379C>G (p.Tyr793Ter)
c.1995C>G (p.Tyr665Ter)
1g.97193201G=CA1182758278DPYD,DPYD-AS1c.2490C= (p.Tyr830=)
n.65-72213G=
c.2274C= (p.Tyr758=)
c.2379C= (p.Tyr793=)
c.1995C= (p.Tyr665=)
1g.97193201G>TCA341373553DPYD,DPYD-AS1c.2490C>A (p.Tyr830Ter)
n.65-72213G>T
c.2274C>A (p.Tyr758Ter)
c.2379C>A (p.Tyr793Ter)
c.1995C>A (p.Tyr665Ter)
1g.97193202T>ACA341373554DPYD,DPYD-AS1c.2489A>T (p.Tyr830Phe)
n.65-72212T>A
c.2273A>T (p.Tyr758Phe)
c.2378A>T (p.Tyr793Phe)
c.1994A>T (p.Tyr665Phe)
1g.97193202T>CCA963018DPYD,DPYD-AS1c.2489A>G (p.Tyr830Cys)
n.65-72212T>C
c.2273A>G (p.Tyr758Cys)
c.2378A>G (p.Tyr793Cys)
c.1994A>G (p.Tyr665Cys)
 dbSNP ExAC gnomAD v2 gnomAD v4
1g.97193202T>GCA341373555DPYD,DPYD-AS1c.2489A>C (p.Tyr830Ser)
n.65-72212T>G
c.2273A>C (p.Tyr758Ser)
c.2378A>C (p.Tyr793Ser)
c.1994A>C (p.Tyr665Ser)
1g.97193202T=CA1182758279DPYD,DPYD-AS1c.2489A= (p.Tyr830=)
n.65-72212T=
c.2273A= (p.Tyr758=)
c.2378A= (p.Tyr793=)
c.1994A= (p.Tyr665=)
1g.97193203A>CCA341373556DPYD,DPYD-AS1c.2488T>G (p.Tyr830Asp)
n.65-72211A>C
c.2272T>G (p.Tyr758Asp)
c.2377T>G (p.Tyr793Asp)
c.1993T>G (p.Tyr665Asp)
1g.97193203A>GCA341373557DPYD,DPYD-AS1c.2488T>C (p.Tyr830His)
n.65-72211A>G
c.2272T>C (p.Tyr758His)
c.2377T>C (p.Tyr793His)
c.1993T>C (p.Tyr665His)
1g.97193203A>TCA341373558DPYD,DPYD-AS1c.2488T>A (p.Tyr830Asn)
n.65-72211A>T
c.2272T>A (p.Tyr758Asn)
c.2377T>A (p.Tyr793Asn)
c.1993T>A (p.Tyr665Asn)
1g.97193204G>ACA419137290DPYD,DPYD-AS1c.2487C>T (p.Asp829=)
n.65-72210G>A
c.2271C>T (p.Asp757=)
c.2376C>T (p.Asp792=)
c.1992C>T (p.Asp664=)
1g.97193204G>CCA341373559DPYD,DPYD-AS1c.2487C>G (p.Asp829Glu)
n.65-72210G>C
c.2271C>G (p.Asp757Glu)
c.2376C>G (p.Asp792Glu)
c.1992C>G (p.Asp664Glu)
1g.97193204G>TCA341373560DPYD,DPYD-AS1c.2487C>A (p.Asp829Glu)
n.65-72210G>T
c.2271C>A (p.Asp757Glu)
c.2376C>A (p.Asp792Glu)
c.1992C>A (p.Asp664Glu)
1g.97193205T>ACA341373563DPYD,DPYD-AS1c.2486A>T (p.Asp829Val)
n.65-72209T>A
c.2270A>T (p.Asp757Val)
c.2375A>T (p.Asp792Val)
c.1991A>T (p.Asp664Val)
1g.97193205T>CCA341373561DPYD,DPYD-AS1c.2486A>G (p.Asp829Gly)
n.65-72209T>C
c.2270A>G (p.Asp757Gly)
c.2375A>G (p.Asp792Gly)
c.1991A>G (p.Asp664Gly)
1g.97193205T>GCA341373562DPYD,DPYD-AS1c.2486A>C (p.Asp829Ala)
n.65-72209T>G
c.2270A>C (p.Asp757Ala)
c.2375A>C (p.Asp792Ala)
c.1991A>C (p.Asp664Ala)
1g.97193206C>ACA341373564DPYD,DPYD-AS1c.2485G>T (p.Asp829Tyr)
n.65-72208C>A
c.2269G>T (p.Asp757Tyr)
c.2374G>T (p.Asp792Tyr)
c.1990G>T (p.Asp664Tyr)
1g.97193206C=CA1143374355DPYD,DPYD-AS1c.2485G= (p.Asp829=)
n.65-72208C=
c.2269G= (p.Asp757=)
c.2374G= (p.Asp792=)
c.1990G= (p.Asp664=)
1g.97193206C>GCA341373565DPYD,DPYD-AS1c.2485G>C (p.Asp829His)
n.65-72208C>G
c.2269G>C (p.Asp757His)
c.2374G>C (p.Asp792His)
c.1990G>C (p.Asp664His)
1g.97193206C>TCA963019DPYD,DPYD-AS1c.2485G>A (p.Asp829Asn)
n.65-72208C>T
c.2269G>A (p.Asp757Asn)
c.2374G>A (p.Asp792Asn)
c.1990G>A (p.Asp664Asn)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
1g.97193207T>ACA341373566DPYD,DPYD-AS1c.2484A>T (p.Glu828Asp)
n.65-72207T>A
c.2268A>T (p.Glu756Asp)
c.2373A>T (p.Glu791Asp)
c.1989A>T (p.Glu663Asp)
1g.97193207T>CCA419137306DPYD,DPYD-AS1c.2484A>G (p.Glu828=)
n.65-72207T>C
c.2268A>G (p.Glu756=)
c.2373A>G (p.Glu791=)
c.1989A>G (p.Glu663=)
1g.97193207T>GCA341373567DPYD,DPYD-AS1c.2484A>C (p.Glu828Asp)
n.65-72207T>G
c.2268A>C (p.Glu756Asp)
c.2373A>C (p.Glu791Asp)
c.1989A>C (p.Glu663Asp)
1g.97193208T>ACA341373568DPYD,DPYD-AS1c.2483A>T (p.Glu828Val)
n.65-72206T>A
c.2267A>T (p.Glu756Val)
c.2372A>T (p.Glu791Val)
c.1988A>T (p.Glu663Val)
 gnomAD v4
1g.97193208T>CCA341373569DPYD,DPYD-AS1c.2483A>G (p.Glu828Gly)
n.65-72206T>C
c.2267A>G (p.Glu756Gly)
c.2372A>G (p.Glu791Gly)
c.1988A>G (p.Glu663Gly)
1g.97193208T>GCA341373570DPYD,DPYD-AS1c.2483A>C (p.Glu828Ala)
n.65-72206T>G
c.2267A>C (p.Glu756Ala)
c.2372A>C (p.Glu791Ala)
c.1988A>C (p.Glu663Ala)

Number of alleles fetched