Chr Mutation (hg38) CAid Gene Transcript Linkouts
17g.42322341T>ACA399581495STAT3c.2042A>T (p.Glu681Val)
c.*434A>T (n.*434A>T)
c.2015A>T (p.Glu672Val)
n.1495A>T
c.*430A>T (n.*430A>T)
c.2138A>T (p.Glu713Val)
n.2242A>T
c.2021A>T (p.Glu674Val)
c.1958A>T (p.Glu653Val)
c.2057A>T (p.Glu686Val)
n.2479A>T
c.1946A>T (p.Glu649Val)
n.2459A>T
n.2285A>T
c.1748A>T (p.Glu583Val)
c.1964A>T (p.Glu655Val)
c.1982A>T (p.Glu661Val)
17g.42322341T>CCA399581498STAT3c.2042A>G (p.Glu681Gly)
c.*434A>G (n.*434A>G)
c.2015A>G (p.Glu672Gly)
n.1495A>G
c.*430A>G (n.*430A>G)
c.2138A>G (p.Glu713Gly)
n.2242A>G
c.2021A>G (p.Glu674Gly)
c.1958A>G (p.Glu653Gly)
c.2057A>G (p.Glu686Gly)
n.2479A>G
c.1946A>G (p.Glu649Gly)
n.2459A>G
n.2285A>G
c.1748A>G (p.Glu583Gly)
c.1964A>G (p.Glu655Gly)
c.1982A>G (p.Glu661Gly)
17g.42322341T>GCA399581507STAT3c.2042A>C (p.Glu681Ala)
c.*434A>C (n.*434A>C)
c.2015A>C (p.Glu672Ala)
n.1495A>C
c.*430A>C (n.*430A>C)
c.2138A>C (p.Glu713Ala)
n.2242A>C
c.2021A>C (p.Glu674Ala)
c.1958A>C (p.Glu653Ala)
c.2057A>C (p.Glu686Ala)
n.2479A>C
c.1946A>C (p.Glu649Ala)
n.2459A>C
n.2285A>C
c.1748A>C (p.Glu583Ala)
c.1964A>C (p.Glu655Ala)
c.1982A>C (p.Glu661Ala)
17g.42322342C>ACA399581509STAT3c.2041G>T (p.Glu681Ter)
c.*433G>T (n.*433G>T)
c.2014G>T (p.Glu672Ter)
n.1494G>T
c.*429G>T (n.*429G>T)
c.2137G>T (p.Glu713Ter)
n.2241G>T
c.2020G>T (p.Glu674Ter)
c.1957G>T (p.Glu653Ter)
c.2056G>T (p.Glu686Ter)
n.2478G>T
c.1945G>T (p.Glu649Ter)
n.2458G>T
n.2284G>T
c.1747G>T (p.Glu583Ter)
c.1963G>T (p.Glu655Ter)
c.1981G>T (p.Glu661Ter)
 dbSNP
17g.42322342C>GCA399581515STAT3c.2041G>C (p.Glu681Gln)
c.*433G>C (n.*433G>C)
c.2014G>C (p.Glu672Gln)
n.1494G>C
c.*429G>C (n.*429G>C)
c.2137G>C (p.Glu713Gln)
n.2241G>C
c.2020G>C (p.Glu674Gln)
c.1957G>C (p.Glu653Gln)
c.2056G>C (p.Glu686Gln)
n.2478G>C
c.1945G>C (p.Glu649Gln)
n.2458G>C
n.2284G>C
c.1747G>C (p.Glu583Gln)
c.1963G>C (p.Glu655Gln)
c.1981G>C (p.Glu661Gln)
 dbSNP
17g.42322342C>TCA399581517STAT3c.2041G>A (p.Glu681Lys)
c.*433G>A (n.*433G>A)
c.2014G>A (p.Glu672Lys)
n.1494G>A
c.*429G>A (n.*429G>A)
c.2137G>A (p.Glu713Lys)
n.2241G>A
c.2020G>A (p.Glu674Lys)
c.1957G>A (p.Glu653Lys)
c.2056G>A (p.Glu686Lys)
n.2478G>A
c.1945G>A (p.Glu649Lys)
n.2458G>A
n.2284G>A
c.1747G>A (p.Glu583Lys)
c.1963G>A (p.Glu655Lys)
c.1981G>A (p.Glu661Lys)
 dbSNP
17g.42322343C>ACA399581518STAT3c.2040G>T (p.Glu680Asp)
c.*432G>T (n.*432G>T)
c.2013G>T (p.Glu671Asp)
n.1493G>T
c.*428G>T (n.*428G>T)
c.2136G>T (p.Glu712Asp)
n.2240G>T
c.2019G>T (p.Glu673Asp)
c.1956G>T (p.Glu652Asp)
c.2055G>T (p.Glu685Asp)
n.2477G>T
c.1944G>T (p.Glu648Asp)
n.2457G>T
n.2283G>T
c.1746G>T (p.Glu582Asp)
c.1962G>T (p.Glu654Asp)
c.1980G>T (p.Glu660Asp)
17g.42322343C>GCA399581519STAT3c.2040G>C (p.Glu680Asp)
c.*432G>C (n.*432G>C)
c.2013G>C (p.Glu671Asp)
n.1493G>C
c.*428G>C (n.*428G>C)
c.2136G>C (p.Glu712Asp)
n.2240G>C
c.2019G>C (p.Glu673Asp)
c.1956G>C (p.Glu652Asp)
c.2055G>C (p.Glu685Asp)
n.2477G>C
c.1944G>C (p.Glu648Asp)
n.2457G>C
n.2283G>C
c.1746G>C (p.Glu582Asp)
c.1962G>C (p.Glu654Asp)
c.1980G>C (p.Glu660Asp)
17g.42322343C>TCA500061033STAT3c.2040G>A (p.Glu680=)
c.*432G>A (n.*432G>A)
c.2013G>A (p.Glu671=)
n.1493G>A
c.*428G>A (n.*428G>A)
c.2136G>A (p.Glu712=)
n.2240G>A
c.2019G>A (p.Glu673=)
c.1956G>A (p.Glu652=)
c.2055G>A (p.Glu685=)
n.2477G>A
c.1944G>A (p.Glu648=)
n.2457G>A
n.2283G>A
c.1746G>A (p.Glu582=)
c.1962G>A (p.Glu654=)
c.1980G>A (p.Glu660=)
 dbSNP
17g.42322344T>ACA399581520STAT3c.2039A>T (p.Glu680Val)
c.*431A>T (n.*431A>T)
c.2012A>T (p.Glu671Val)
n.1492A>T
c.*427A>T (n.*427A>T)
c.2135A>T (p.Glu712Val)
n.2239A>T
c.2018A>T (p.Glu673Val)
c.1955A>T (p.Glu652Val)
c.2054A>T (p.Glu685Val)
n.2476A>T
c.1943A>T (p.Glu648Val)
n.2456A>T
n.2282A>T
c.1745A>T (p.Glu582Val)
c.1961A>T (p.Glu654Val)
c.1979A>T (p.Glu660Val)
17g.42322344T>CCA399581522STAT3c.2039A>G (p.Glu680Gly)
c.*431A>G (n.*431A>G)
c.2012A>G (p.Glu671Gly)
n.1492A>G
c.*427A>G (n.*427A>G)
c.2135A>G (p.Glu712Gly)
n.2239A>G
c.2018A>G (p.Glu673Gly)
c.1955A>G (p.Glu652Gly)
c.2054A>G (p.Glu685Gly)
n.2476A>G
c.1943A>G (p.Glu648Gly)
n.2456A>G
n.2282A>G
c.1745A>G (p.Glu582Gly)
c.1961A>G (p.Glu654Gly)
c.1979A>G (p.Glu660Gly)
 dbSNP
17g.42322344T>GCA399581523STAT3c.2039A>C (p.Glu680Ala)
c.*431A>C (n.*431A>C)
c.2012A>C (p.Glu671Ala)
n.1492A>C
c.*427A>C (n.*427A>C)
c.2135A>C (p.Glu712Ala)
n.2239A>C
c.2018A>C (p.Glu673Ala)
c.1955A>C (p.Glu652Ala)
c.2054A>C (p.Glu685Ala)
n.2476A>C
c.1943A>C (p.Glu648Ala)
n.2456A>C
n.2282A>C
c.1745A>C (p.Glu582Ala)
c.1961A>C (p.Glu654Ala)
c.1979A>C (p.Glu660Ala)
17g.42322345C>ACA399581524STAT3c.2038G>T (p.Glu680Ter)
c.*430G>T (n.*430G>T)
c.2011G>T (p.Glu671Ter)
n.1491G>T
c.*426G>T (n.*426G>T)
c.2134G>T (p.Glu712Ter)
n.2238G>T
c.2017G>T (p.Glu673Ter)
c.1954G>T (p.Glu652Ter)
c.2053G>T (p.Glu685Ter)
n.2475G>T
c.1942G>T (p.Glu648Ter)
n.2455G>T
n.2281G>T
c.1744G>T (p.Glu582Ter)
c.1960G>T (p.Glu654Ter)
c.1978G>T (p.Glu660Ter)
17g.42322345C>GCA399581526STAT3c.2038G>C (p.Glu680Gln)
c.*430G>C (n.*430G>C)
c.2011G>C (p.Glu671Gln)
n.1491G>C
c.*426G>C (n.*426G>C)
c.2134G>C (p.Glu712Gln)
n.2238G>C
c.2017G>C (p.Glu673Gln)
c.1954G>C (p.Glu652Gln)
c.2053G>C (p.Glu685Gln)
n.2475G>C
c.1942G>C (p.Glu648Gln)
n.2455G>C
n.2281G>C
c.1744G>C (p.Glu582Gln)
c.1960G>C (p.Glu654Gln)
c.1978G>C (p.Glu660Gln)
 dbSNP
17g.42322345C>TCA399581528STAT3c.2038G>A (p.Glu680Lys)
c.*430G>A (n.*430G>A)
c.2011G>A (p.Glu671Lys)
n.1491G>A
c.*426G>A (n.*426G>A)
c.2134G>A (p.Glu712Lys)
n.2238G>A
c.2017G>A (p.Glu673Lys)
c.1954G>A (p.Glu652Lys)
c.2053G>A (p.Glu685Lys)
n.2475G>A
c.1942G>A (p.Glu648Lys)
n.2455G>A
n.2281G>A
c.1744G>A (p.Glu582Lys)
c.1960G>A (p.Glu654Lys)
c.1978G>A (p.Glu660Lys)
 dbSNP
17g.42322346C>ACA399581532STAT3c.2037G>T (p.Lys679Asn)
c.*429G>T (n.*429G>T)
c.2010G>T (p.Lys670Asn)
n.1490G>T
c.*425G>T (n.*425G>T)
c.2133G>T (p.Lys711Asn)
n.2237G>T
c.2016G>T (p.Lys672Asn)
c.1953G>T (p.Lys651Asn)
c.2052G>T (p.Lys684Asn)
n.2474G>T
c.1941G>T (p.Lys647Asn)
n.2454G>T
n.2280G>T
c.1743G>T (p.Lys581Asn)
c.1959G>T (p.Lys653Asn)
c.1977G>T (p.Lys659Asn)
17g.42322346C>GCA399581530STAT3c.2037G>C (p.Lys679Asn)
c.*429G>C (n.*429G>C)
c.2010G>C (p.Lys670Asn)
n.1490G>C
c.*425G>C (n.*425G>C)
c.2133G>C (p.Lys711Asn)
n.2237G>C
c.2016G>C (p.Lys672Asn)
c.1953G>C (p.Lys651Asn)
c.2052G>C (p.Lys684Asn)
n.2474G>C
c.1941G>C (p.Lys647Asn)
n.2454G>C
n.2280G>C
c.1743G>C (p.Lys581Asn)
c.1959G>C (p.Lys653Asn)
c.1977G>C (p.Lys659Asn)
17g.42322346C>TCA500061034STAT3c.2037G>A (p.Lys679=)
c.*429G>A (n.*429G>A)
c.2010G>A (p.Lys670=)
n.1490G>A
c.*425G>A (n.*425G>A)
c.2133G>A (p.Lys711=)
n.2237G>A
c.2016G>A (p.Lys672=)
c.1953G>A (p.Lys651=)
c.2052G>A (p.Lys684=)
n.2474G>A
c.1941G>A (p.Lys647=)
n.2454G>A
n.2280G>A
c.1743G>A (p.Lys581=)
c.1959G>A (p.Lys653=)
c.1977G>A (p.Lys659=)
 dbSNP
17g.42322347T>ACA399581533STAT3c.2036A>T (p.Lys679Met)
c.*428A>T (n.*428A>T)
c.2009A>T (p.Lys670Met)
n.1489A>T
c.*424A>T (n.*424A>T)
c.2132A>T (p.Lys711Met)
n.2236A>T
c.2015A>T (p.Lys672Met)
c.1952A>T (p.Lys651Met)
c.2051A>T (p.Lys684Met)
n.2473A>T
c.1940A>T (p.Lys647Met)
n.2453A>T
n.2279A>T
c.1742A>T (p.Lys581Met)
c.1958A>T (p.Lys653Met)
c.1976A>T (p.Lys659Met)
17g.42322347T>CCA399581535STAT3c.2036A>G (p.Lys679Arg)
c.*428A>G (n.*428A>G)
c.2009A>G (p.Lys670Arg)
n.1489A>G
c.*424A>G (n.*424A>G)
c.2132A>G (p.Lys711Arg)
n.2236A>G
c.2015A>G (p.Lys672Arg)
c.1952A>G (p.Lys651Arg)
c.2051A>G (p.Lys684Arg)
n.2473A>G
c.1940A>G (p.Lys647Arg)
n.2453A>G
n.2279A>G
c.1742A>G (p.Lys581Arg)
c.1958A>G (p.Lys653Arg)
c.1976A>G (p.Lys659Arg)
17g.42322347T>GCA399581537STAT3c.2036A>C (p.Lys679Thr)
c.*428A>C (n.*428A>C)
c.2009A>C (p.Lys670Thr)
n.1489A>C
c.*424A>C (n.*424A>C)
c.2132A>C (p.Lys711Thr)
n.2236A>C
c.2015A>C (p.Lys672Thr)
c.1952A>C (p.Lys651Thr)
c.2051A>C (p.Lys684Thr)
n.2473A>C
c.1940A>C (p.Lys647Thr)
n.2453A>C
n.2279A>C
c.1742A>C (p.Lys581Thr)
c.1958A>C (p.Lys653Thr)
c.1976A>C (p.Lys659Thr)
17g.42322348T>ACA399581541STAT3c.2035A>T (p.Lys679Ter)
c.*427A>T (n.*427A>T)
c.2008A>T (p.Lys670Ter)
n.1488A>T
c.*423A>T (n.*423A>T)
c.2131A>T (p.Lys711Ter)
n.2235A>T
c.2014A>T (p.Lys672Ter)
c.1951A>T (p.Lys651Ter)
c.2050A>T (p.Lys684Ter)
n.2472A>T
c.1939A>T (p.Lys647Ter)
n.2452A>T
n.2278A>T
c.1741A>T (p.Lys581Ter)
c.1957A>T (p.Lys653Ter)
c.1975A>T (p.Lys659Ter)
17g.42322348T>CCA399581543STAT3c.2035A>G (p.Lys679Glu)
c.*427A>G (n.*427A>G)
c.2008A>G (p.Lys670Glu)
n.1488A>G
c.*423A>G (n.*423A>G)
c.2131A>G (p.Lys711Glu)
n.2235A>G
c.2014A>G (p.Lys672Glu)
c.1951A>G (p.Lys651Glu)
c.2050A>G (p.Lys684Glu)
n.2472A>G
c.1939A>G (p.Lys647Glu)
n.2452A>G
n.2278A>G
c.1741A>G (p.Lys581Glu)
c.1957A>G (p.Lys653Glu)
c.1975A>G (p.Lys659Glu)
17g.42322348T>GCA399581545STAT3c.2035A>C (p.Lys679Gln)
c.*427A>C (n.*427A>C)
c.2008A>C (p.Lys670Gln)
n.1488A>C
c.*423A>C (n.*423A>C)
c.2131A>C (p.Lys711Gln)
n.2235A>C
c.2014A>C (p.Lys672Gln)
c.1951A>C (p.Lys651Gln)
c.2050A>C (p.Lys684Gln)
n.2472A>C
c.1939A>C (p.Lys647Gln)
n.2452A>C
n.2278A>C
c.1741A>C (p.Lys581Gln)
c.1957A>C (p.Lys653Gln)
c.1975A>C (p.Lys659Gln)
17g.42322349G>ACA500061035STAT3c.2034C>T (p.Pro678=)
c.*426C>T (n.*426C>T)
c.2007C>T (p.Pro669=)
n.1487C>T
c.*422C>T (n.*422C>T)
c.2130C>T (p.Pro710=)
n.2234C>T
c.2013C>T (p.Pro671=)
c.1950C>T (p.Pro650=)
c.2049C>T (p.Pro683=)
n.2471C>T
c.1938C>T (p.Pro646=)
n.2451C>T
n.2277C>T
c.1740C>T (p.Pro580=)
c.1956C>T (p.Pro652=)
c.1974C>T (p.Pro658=)
17g.42322349G>CCA500061036STAT3c.2034C>G (p.Pro678=)
c.*426C>G (n.*426C>G)
c.2007C>G (p.Pro669=)
n.1487C>G
c.*422C>G (n.*422C>G)
c.2130C>G (p.Pro710=)
n.2234C>G
c.2013C>G (p.Pro671=)
c.1950C>G (p.Pro650=)
c.2049C>G (p.Pro683=)
n.2471C>G
c.1938C>G (p.Pro646=)
n.2451C>G
n.2277C>G
c.1740C>G (p.Pro580=)
c.1956C>G (p.Pro652=)
c.1974C>G (p.Pro658=)
 ClinVar dbSNP gnomAD v4
17g.42322349G=CA2260430715STAT3c.2034C= (p.Pro678=)
c.*426C= (n.*426C=)
c.2007C= (p.Pro669=)
n.1487C=
c.*422C= (n.*422C=)
c.2130C= (p.Pro710=)
n.2234C=
c.2013C= (p.Pro671=)
c.1950C= (p.Pro650=)
c.2049C= (p.Pro683=)
n.2471C=
c.1938C= (p.Pro646=)
n.2451C=
n.2277C=
c.1740C= (p.Pro580=)
c.1956C= (p.Pro652=)
c.1974C= (p.Pro658=)
17g.42322349G>TCA500061037STAT3c.2034C>A (p.Pro678=)
c.*426C>A (n.*426C>A)
c.2007C>A (p.Pro669=)
n.1487C>A
c.*422C>A (n.*422C>A)
c.2130C>A (p.Pro710=)
n.2234C>A
c.2013C>A (p.Pro671=)
c.1950C>A (p.Pro650=)
c.2049C>A (p.Pro683=)
n.2471C>A
c.1938C>A (p.Pro646=)
n.2451C>A
n.2277C>A
c.1740C>A (p.Pro580=)
c.1956C>A (p.Pro652=)
c.1974C>A (p.Pro658=)
 dbSNP
17g.42322350G>ACA399581546STAT3c.2033C>T (p.Pro678Leu)
c.*425C>T (n.*425C>T)
c.2006C>T (p.Pro669Leu)
n.1486C>T
c.*421C>T (n.*421C>T)
c.2129C>T (p.Pro710Leu)
n.2233C>T
c.2012C>T (p.Pro671Leu)
c.1949C>T (p.Pro650Leu)
c.2048C>T (p.Pro683Leu)
n.2470C>T
c.1937C>T (p.Pro646Leu)
n.2450C>T
n.2276C>T
c.1739C>T (p.Pro580Leu)
c.1955C>T (p.Pro652Leu)
c.1973C>T (p.Pro658Leu)
17g.42322350G>CCA399581549STAT3c.2033C>G (p.Pro678Arg)
c.*425C>G (n.*425C>G)
c.2006C>G (p.Pro669Arg)
n.1486C>G
c.*421C>G (n.*421C>G)
c.2129C>G (p.Pro710Arg)
n.2233C>G
c.2012C>G (p.Pro671Arg)
c.1949C>G (p.Pro650Arg)
c.2048C>G (p.Pro683Arg)
n.2470C>G
c.1937C>G (p.Pro646Arg)
n.2450C>G
n.2276C>G
c.1739C>G (p.Pro580Arg)
c.1955C>G (p.Pro652Arg)
c.1973C>G (p.Pro658Arg)
 dbSNP
17g.42322350G>TCA399581548STAT3c.2033C>A (p.Pro678His)
c.*425C>A (n.*425C>A)
c.2006C>A (p.Pro669His)
n.1486C>A
c.*421C>A (n.*421C>A)
c.2129C>A (p.Pro710His)
n.2233C>A
c.2012C>A (p.Pro671His)
c.1949C>A (p.Pro650His)
c.2048C>A (p.Pro683His)
n.2470C>A
c.1937C>A (p.Pro646His)
n.2450C>A
n.2276C>A
c.1739C>A (p.Pro580His)
c.1955C>A (p.Pro652His)
c.1973C>A (p.Pro658His)
 ClinVar dbSNP
17g.42322351G>ACA399581551STAT3c.2032C>T (p.Pro678Ser)
c.*424C>T (n.*424C>T)
c.2005C>T (p.Pro669Ser)
n.1485C>T
c.*420C>T (n.*420C>T)
c.2128C>T (p.Pro710Ser)
n.2232C>T
c.2011C>T (p.Pro671Ser)
c.1948C>T (p.Pro650Ser)
c.2047C>T (p.Pro683Ser)
n.2469C>T
c.1936C>T (p.Pro646Ser)
n.2449C>T
n.2275C>T
c.1738C>T (p.Pro580Ser)
c.1954C>T (p.Pro652Ser)
c.1972C>T (p.Pro658Ser)
17g.42322351G>CCA399581552STAT3c.2032C>G (p.Pro678Ala)
c.*424C>G (n.*424C>G)
c.2005C>G (p.Pro669Ala)
n.1485C>G
c.*420C>G (n.*420C>G)
c.2128C>G (p.Pro710Ala)
n.2232C>G
c.2011C>G (p.Pro671Ala)
c.1948C>G (p.Pro650Ala)
c.2047C>G (p.Pro683Ala)
n.2469C>G
c.1936C>G (p.Pro646Ala)
n.2449C>G
n.2275C>G
c.1738C>G (p.Pro580Ala)
c.1954C>G (p.Pro652Ala)
c.1972C>G (p.Pro658Ala)
 gnomAD v4
17g.42322351G>TCA399581554STAT3c.2032C>A (p.Pro678Thr)
c.*424C>A (n.*424C>A)
c.2005C>A (p.Pro669Thr)
n.1485C>A
c.*420C>A (n.*420C>A)
c.2128C>A (p.Pro710Thr)
n.2232C>A
c.2011C>A (p.Pro671Thr)
c.1948C>A (p.Pro650Thr)
c.2047C>A (p.Pro683Thr)
n.2469C>A
c.1936C>A (p.Pro646Thr)
n.2449C>A
n.2275C>A
c.1738C>A (p.Pro580Thr)
c.1954C>A (p.Pro652Thr)
c.1972C>A (p.Pro658Thr)
 gnomAD v4
17g.42322352A>CCA399581556STAT3c.2031T>G (p.Ile677Met)
c.*423T>G (n.*423T>G)
c.2004T>G (p.Ile668Met)
n.1484T>G
c.*419T>G (n.*419T>G)
c.2127T>G (p.Ile709Met)
n.2231T>G
c.2010T>G (p.Ile670Met)
c.1947T>G (p.Ile649Met)
c.2046T>G (p.Ile682Met)
n.2468T>G
c.1935T>G (p.Ile645Met)
n.2448T>G
n.2274T>G
c.1737T>G (p.Ile579Met)
c.1953T>G (p.Ile651Met)
c.1971T>G (p.Ile657Met)
17g.42322352A>GCA500061039STAT3c.2031T>C (p.Ile677=)
c.*423T>C (n.*423T>C)
c.2004T>C (p.Ile668=)
n.1484T>C
c.*419T>C (n.*419T>C)
c.2127T>C (p.Ile709=)
n.2231T>C
c.2010T>C (p.Ile670=)
c.1947T>C (p.Ile649=)
c.2046T>C (p.Ile682=)
n.2468T>C
c.1935T>C (p.Ile645=)
n.2448T>C
n.2274T>C
c.1737T>C (p.Ile579=)
c.1953T>C (p.Ile651=)
c.1971T>C (p.Ile657=)
17g.42322352A>TCA500061038STAT3c.2031T>A (p.Ile677=)
c.*423T>A (n.*423T>A)
c.2004T>A (p.Ile668=)
n.1484T>A
c.*419T>A (n.*419T>A)
c.2127T>A (p.Ile709=)
n.2231T>A
c.2010T>A (p.Ile670=)
c.1947T>A (p.Ile649=)
c.2046T>A (p.Ile682=)
n.2468T>A
c.1935T>A (p.Ile645=)
n.2448T>A
n.2274T>A
c.1737T>A (p.Ile579=)
c.1953T>A (p.Ile651=)
c.1971T>A (p.Ile657=)
 dbSNP
17g.42322353A>CCA399581558STAT3c.2030T>G (p.Ile677Ser)
c.*422T>G (n.*422T>G)
c.2003T>G (p.Ile668Ser)
n.1483T>G
c.*418T>G (n.*418T>G)
c.2126T>G (p.Ile709Ser)
n.2230T>G
c.2009T>G (p.Ile670Ser)
c.1946T>G (p.Ile649Ser)
c.2045T>G (p.Ile682Ser)
n.2467T>G
c.1934T>G (p.Ile645Ser)
n.2447T>G
n.2273T>G
c.1736T>G (p.Ile579Ser)
c.1952T>G (p.Ile651Ser)
c.1970T>G (p.Ile657Ser)
17g.42322353A>GCA399581561STAT3c.2030T>C (p.Ile677Thr)
c.*422T>C (n.*422T>C)
c.2003T>C (p.Ile668Thr)
n.1483T>C
c.*418T>C (n.*418T>C)
c.2126T>C (p.Ile709Thr)
n.2230T>C
c.2009T>C (p.Ile670Thr)
c.1946T>C (p.Ile649Thr)
c.2045T>C (p.Ile682Thr)
n.2467T>C
c.1934T>C (p.Ile645Thr)
n.2447T>C
n.2273T>C
c.1736T>C (p.Ile579Thr)
c.1952T>C (p.Ile651Thr)
c.1970T>C (p.Ile657Thr)
17g.42322353A>TCA399581562STAT3c.2030T>A (p.Ile677Asn)
c.*422T>A (n.*422T>A)
c.2003T>A (p.Ile668Asn)
n.1483T>A
c.*418T>A (n.*418T>A)
c.2126T>A (p.Ile709Asn)
n.2230T>A
c.2009T>A (p.Ile670Asn)
c.1946T>A (p.Ile649Asn)
c.2045T>A (p.Ile682Asn)
n.2467T>A
c.1934T>A (p.Ile645Asn)
n.2447T>A
n.2273T>A
c.1736T>A (p.Ile579Asn)
c.1952T>A (p.Ile651Asn)
c.1970T>A (p.Ile657Asn)
 dbSNP
17g.42322354T>ACA399581566STAT3c.2029A>T (p.Ile677Phe)
c.*421A>T (n.*421A>T)
c.2002A>T (p.Ile668Phe)
n.1482A>T
c.*417A>T (n.*417A>T)
c.2125A>T (p.Ile709Phe)
n.2229A>T
c.2008A>T (p.Ile670Phe)
c.1945A>T (p.Ile649Phe)
c.2044A>T (p.Ile682Phe)
n.2466A>T
c.1933A>T (p.Ile645Phe)
n.2446A>T
n.2272A>T
c.1735A>T (p.Ile579Phe)
c.1951A>T (p.Ile651Phe)
c.1969A>T (p.Ile657Phe)
 dbSNP
17g.42322354T>CCA399581578STAT3c.2029A>G (p.Ile677Val)
c.*421A>G (n.*421A>G)
c.2002A>G (p.Ile668Val)
n.1482A>G
c.*417A>G (n.*417A>G)
c.2125A>G (p.Ile709Val)
n.2229A>G
c.2008A>G (p.Ile670Val)
c.1945A>G (p.Ile649Val)
c.2044A>G (p.Ile682Val)
n.2466A>G
c.1933A>G (p.Ile645Val)
n.2446A>G
n.2272A>G
c.1735A>G (p.Ile579Val)
c.1951A>G (p.Ile651Val)
c.1969A>G (p.Ile657Val)
 dbSNP
17g.42322354T>GCA399581580STAT3c.2029A>C (p.Ile677Leu)
c.*421A>C (n.*421A>C)
c.2002A>C (p.Ile668Leu)
n.1482A>C
c.*417A>C (n.*417A>C)
c.2125A>C (p.Ile709Leu)
n.2229A>C
c.2008A>C (p.Ile670Leu)
c.1945A>C (p.Ile649Leu)
c.2044A>C (p.Ile682Leu)
n.2466A>C
c.1933A>C (p.Ile645Leu)
n.2446A>C
n.2272A>C
c.1735A>C (p.Ile579Leu)
c.1951A>C (p.Ile651Leu)
c.1969A>C (p.Ile657Leu)
17g.42322355G>ACA500061040STAT3c.2028C>T (p.Asp676=)
c.*420C>T (n.*420C>T)
c.2001C>T (p.Asp667=)
n.1481C>T
c.*416C>T (n.*416C>T)
c.2124C>T (p.Asp708=)
n.2228C>T
c.2007C>T (p.Asp669=)
c.1944C>T (p.Asp648=)
c.2043C>T (p.Asp681=)
n.2465C>T
c.1932C>T (p.Asp644=)
n.2445C>T
n.2271C>T
c.1734C>T (p.Asp578=)
c.1950C>T (p.Asp650=)
c.1968C>T (p.Asp656=)
17g.42322355G>CCA399581589STAT3c.2028C>G (p.Asp676Glu)
c.*420C>G (n.*420C>G)
c.2001C>G (p.Asp667Glu)
n.1481C>G
c.*416C>G (n.*416C>G)
c.2124C>G (p.Asp708Glu)
n.2228C>G
c.2007C>G (p.Asp669Glu)
c.1944C>G (p.Asp648Glu)
c.2043C>G (p.Asp681Glu)
n.2465C>G
c.1932C>G (p.Asp644Glu)
n.2445C>G
n.2271C>G
c.1734C>G (p.Asp578Glu)
c.1950C>G (p.Asp650Glu)
c.1968C>G (p.Asp656Glu)
17g.42322355G>TCA399581592STAT3c.2028C>A (p.Asp676Glu)
c.*420C>A (n.*420C>A)
c.2001C>A (p.Asp667Glu)
n.1481C>A
c.*416C>A (n.*416C>A)
c.2124C>A (p.Asp708Glu)
n.2228C>A
c.2007C>A (p.Asp669Glu)
c.1944C>A (p.Asp648Glu)
c.2043C>A (p.Asp681Glu)
n.2465C>A
c.1932C>A (p.Asp644Glu)
n.2445C>A
n.2271C>A
c.1734C>A (p.Asp578Glu)
c.1950C>A (p.Asp650Glu)
c.1968C>A (p.Asp656Glu)
17g.42322356T>ACA399581595STAT3c.2027A>T (p.Asp676Val)
c.*419A>T (n.*419A>T)
c.2000A>T (p.Asp667Val)
n.1480A>T
c.*415A>T (n.*415A>T)
c.2123A>T (p.Asp708Val)
n.2227A>T
c.2006A>T (p.Asp669Val)
c.1943A>T (p.Asp648Val)
c.2042A>T (p.Asp681Val)
n.2464A>T
c.1931A>T (p.Asp644Val)
n.2444A>T
n.2270A>T
c.1733A>T (p.Asp578Val)
c.1949A>T (p.Asp650Val)
c.1967A>T (p.Asp656Val)
 dbSNP
17g.42322356T>CCA399581596STAT3c.2027A>G (p.Asp676Gly)
c.*419A>G (n.*419A>G)
c.2000A>G (p.Asp667Gly)
n.1480A>G
c.*415A>G (n.*415A>G)
c.2123A>G (p.Asp708Gly)
n.2227A>G
c.2006A>G (p.Asp669Gly)
c.1943A>G (p.Asp648Gly)
c.2042A>G (p.Asp681Gly)
n.2464A>G
c.1931A>G (p.Asp644Gly)
n.2444A>G
n.2270A>G
c.1733A>G (p.Asp578Gly)
c.1949A>G (p.Asp650Gly)
c.1967A>G (p.Asp656Gly)
17g.42322356T>GCA399581594STAT3c.2027A>C (p.Asp676Ala)
c.*419A>C (n.*419A>C)
c.2000A>C (p.Asp667Ala)
n.1480A>C
c.*415A>C (n.*415A>C)
c.2123A>C (p.Asp708Ala)
n.2227A>C
c.2006A>C (p.Asp669Ala)
c.1943A>C (p.Asp648Ala)
c.2042A>C (p.Asp681Ala)
n.2464A>C
c.1931A>C (p.Asp644Ala)
n.2444A>C
n.2270A>C
c.1733A>C (p.Asp578Ala)
c.1949A>C (p.Asp650Ala)
c.1967A>C (p.Asp656Ala)
17g.42322357C>ACA399581599STAT3c.2026G>T (p.Asp676Tyr)
c.*418G>T (n.*418G>T)
c.1999G>T (p.Asp667Tyr)
n.1479G>T
c.*414G>T (n.*414G>T)
c.2122G>T (p.Asp708Tyr)
n.2226G>T
c.2005G>T (p.Asp669Tyr)
c.1942G>T (p.Asp648Tyr)
c.2041G>T (p.Asp681Tyr)
n.2463G>T
c.1930G>T (p.Asp644Tyr)
n.2443G>T
n.2269G>T
c.1732G>T (p.Asp578Tyr)
c.1948G>T (p.Asp650Tyr)
c.1966G>T (p.Asp656Tyr)
17g.42322357C>GCA399581597STAT3c.2026G>C (p.Asp676His)
c.*418G>C (n.*418G>C)
c.1999G>C (p.Asp667His)
n.1479G>C
c.*414G>C (n.*414G>C)
c.2122G>C (p.Asp708His)
n.2226G>C
c.2005G>C (p.Asp669His)
c.1942G>C (p.Asp648His)
c.2041G>C (p.Asp681His)
n.2463G>C
c.1930G>C (p.Asp644His)
n.2443G>C
n.2269G>C
c.1732G>C (p.Asp578His)
c.1948G>C (p.Asp650His)
c.1966G>C (p.Asp656His)
 dbSNP
17g.42322357C>TCA399581598STAT3c.2026G>A (p.Asp676Asn)
c.*418G>A (n.*418G>A)
c.1999G>A (p.Asp667Asn)
n.1479G>A
c.*414G>A (n.*414G>A)
c.2122G>A (p.Asp708Asn)
n.2226G>A
c.2005G>A (p.Asp669Asn)
c.1942G>A (p.Asp648Asn)
c.2041G>A (p.Asp681Asn)
n.2463G>A
c.1930G>A (p.Asp644Asn)
n.2443G>A
n.2269G>A
c.1732G>A (p.Asp578Asn)
c.1948G>A (p.Asp650Asn)
c.1966G>A (p.Asp656Asn)
 dbSNP
17g.42322358A>CCA500061041STAT3c.2025T>G (p.Pro675=)
c.*417T>G (n.*417T>G)
c.1998T>G (p.Pro666=)
n.1478T>G
c.*413T>G (n.*413T>G)
c.2121T>G (p.Pro707=)
n.2225T>G
c.2004T>G (p.Pro668=)
c.1941T>G (p.Pro647=)
c.2040T>G (p.Pro680=)
n.2462T>G
c.1929T>G (p.Pro643=)
n.2442T>G
n.2268T>G
c.1731T>G (p.Pro577=)
c.1947T>G (p.Pro649=)
c.1965T>G (p.Pro655=)
 gnomAD v4
17g.42322358A>GCA500061043STAT3c.2025T>C (p.Pro675=)
c.*417T>C (n.*417T>C)
c.1998T>C (p.Pro666=)
n.1478T>C
c.*413T>C (n.*413T>C)
c.2121T>C (p.Pro707=)
n.2225T>C
c.2004T>C (p.Pro668=)
c.1941T>C (p.Pro647=)
c.2040T>C (p.Pro680=)
n.2462T>C
c.1929T>C (p.Pro643=)
n.2442T>C
n.2268T>C
c.1731T>C (p.Pro577=)
c.1947T>C (p.Pro649=)
c.1965T>C (p.Pro655=)
 dbSNP
17g.42322358A>TCA500061042STAT3c.2025T>A (p.Pro675=)
c.*417T>A (n.*417T>A)
c.1998T>A (p.Pro666=)
n.1478T>A
c.*413T>A (n.*413T>A)
c.2121T>A (p.Pro707=)
n.2225T>A
c.2004T>A (p.Pro668=)
c.1941T>A (p.Pro647=)
c.2040T>A (p.Pro680=)
n.2462T>A
c.1929T>A (p.Pro643=)
n.2442T>A
n.2268T>A
c.1731T>A (p.Pro577=)
c.1947T>A (p.Pro649=)
c.1965T>A (p.Pro655=)
 dbSNP
17g.42322359G>ACA399581602STAT3c.2024C>T (p.Pro675Leu)
c.*416C>T (n.*416C>T)
c.1997C>T (p.Pro666Leu)
n.1477C>T
c.*412C>T (n.*412C>T)
c.2120C>T (p.Pro707Leu)
n.2224C>T
c.2003C>T (p.Pro668Leu)
c.1940C>T (p.Pro647Leu)
c.2039C>T (p.Pro680Leu)
n.2461C>T
c.1928C>T (p.Pro643Leu)
n.2441C>T
n.2267C>T
c.1730C>T (p.Pro577Leu)
c.1946C>T (p.Pro649Leu)
c.1964C>T (p.Pro655Leu)
17g.42322359G>CCA399581604STAT3c.2024C>G (p.Pro675Arg)
c.*416C>G (n.*416C>G)
c.1997C>G (p.Pro666Arg)
n.1477C>G
c.*412C>G (n.*412C>G)
c.2120C>G (p.Pro707Arg)
n.2224C>G
c.2003C>G (p.Pro668Arg)
c.1940C>G (p.Pro647Arg)
c.2039C>G (p.Pro680Arg)
n.2461C>G
c.1928C>G (p.Pro643Arg)
n.2441C>G
n.2267C>G
c.1730C>G (p.Pro577Arg)
c.1946C>G (p.Pro649Arg)
c.1964C>G (p.Pro655Arg)
17g.42322359G>TCA399581607STAT3c.2024C>A (p.Pro675His)
c.*416C>A (n.*416C>A)
c.1997C>A (p.Pro666His)
n.1477C>A
c.*412C>A (n.*412C>A)
c.2120C>A (p.Pro707His)
n.2224C>A
c.2003C>A (p.Pro668His)
c.1940C>A (p.Pro647His)
c.2039C>A (p.Pro680His)
n.2461C>A
c.1928C>A (p.Pro643His)
n.2441C>A
n.2267C>A
c.1730C>A (p.Pro577His)
c.1946C>A (p.Pro649His)
c.1964C>A (p.Pro655His)
17g.42322360G>ACA399581620STAT3c.2023C>T (p.Pro675Ser)
c.*415C>T (n.*415C>T)
c.1996C>T (p.Pro666Ser)
n.1476C>T
c.*411C>T (n.*411C>T)
c.2119C>T (p.Pro707Ser)
n.2223C>T
c.2002C>T (p.Pro668Ser)
c.1939C>T (p.Pro647Ser)
c.2038C>T (p.Pro680Ser)
n.2460C>T
c.1927C>T (p.Pro643Ser)
n.2440C>T
n.2266C>T
c.1729C>T (p.Pro577Ser)
c.1945C>T (p.Pro649Ser)
c.1963C>T (p.Pro655Ser)
 dbSNP COSMIC
17g.42322360G>CCA399581623STAT3c.2023C>G (p.Pro675Ala)
c.*415C>G (n.*415C>G)
c.1996C>G (p.Pro666Ala)
n.1476C>G
c.*411C>G (n.*411C>G)
c.2119C>G (p.Pro707Ala)
n.2223C>G
c.2002C>G (p.Pro668Ala)
c.1939C>G (p.Pro647Ala)
c.2038C>G (p.Pro680Ala)
n.2460C>G
c.1927C>G (p.Pro643Ala)
n.2440C>G
n.2266C>G
c.1729C>G (p.Pro577Ala)
c.1945C>G (p.Pro649Ala)
c.1963C>G (p.Pro655Ala)
 dbSNP
17g.42322360G>TCA399581627STAT3c.2023C>A (p.Pro675Thr)
c.*415C>A (n.*415C>A)
c.1996C>A (p.Pro666Thr)
n.1476C>A
c.*411C>A (n.*411C>A)
c.2119C>A (p.Pro707Thr)
n.2223C>A
c.2002C>A (p.Pro668Thr)
c.1939C>A (p.Pro647Thr)
c.2038C>A (p.Pro680Thr)
n.2460C>A
c.1927C>A (p.Pro643Thr)
n.2440C>A
n.2266C>A
c.1729C>A (p.Pro577Thr)
c.1945C>A (p.Pro649Thr)
c.1963C>A (p.Pro655Thr)
 COSMIC
17g.42322361A=CA2260430716STAT3c.2022T= (p.Tyr674=)
c.*414T= (n.*414T=)
c.1995T= (p.Tyr665=)
n.1475T=
c.*410T= (n.*410T=)
c.2118T= (p.Tyr706=)
n.2222T=
c.2001T= (p.Tyr667=)
c.1938T= (p.Tyr646=)
c.2037T= (p.Tyr679=)
n.2459T=
c.1926T= (p.Tyr642=)
n.2439T=
n.2265T=
c.1728T= (p.Tyr576=)
c.1944T= (p.Tyr648=)
c.1962T= (p.Tyr654=)
17g.42322361A>CCA399581633STAT3c.2022T>G (p.Tyr674Ter)
c.*414T>G (n.*414T>G)
c.1995T>G (p.Tyr665Ter)
n.1475T>G
c.*410T>G (n.*410T>G)
c.2118T>G (p.Tyr706Ter)
n.2222T>G
c.2001T>G (p.Tyr667Ter)
c.1938T>G (p.Tyr646Ter)
c.2037T>G (p.Tyr679Ter)
n.2459T>G
c.1926T>G (p.Tyr642Ter)
n.2439T>G
n.2265T>G
c.1728T>G (p.Tyr576Ter)
c.1944T>G (p.Tyr648Ter)
c.1962T>G (p.Tyr654Ter)
17g.42322361A>GCA8575176STAT3c.2022T>C (p.Tyr674=)
c.*414T>C (n.*414T>C)
c.1995T>C (p.Tyr665=)
n.1475T>C
c.*410T>C (n.*410T>C)
c.2118T>C (p.Tyr706=)
n.2222T>C
c.2001T>C (p.Tyr667=)
c.1938T>C (p.Tyr646=)
c.2037T>C (p.Tyr679=)
n.2459T>C
c.1926T>C (p.Tyr642=)
n.2439T>C
n.2265T>C
c.1728T>C (p.Tyr576=)
c.1944T>C (p.Tyr648=)
c.1962T>C (p.Tyr654=)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
17g.42322361A>TCA399581638STAT3c.2022T>A (p.Tyr674Ter)
c.*414T>A (n.*414T>A)
c.1995T>A (p.Tyr665Ter)
n.1475T>A
c.*410T>A (n.*410T>A)
c.2118T>A (p.Tyr706Ter)
n.2222T>A
c.2001T>A (p.Tyr667Ter)
c.1938T>A (p.Tyr646Ter)
c.2037T>A (p.Tyr679Ter)
n.2459T>A
c.1926T>A (p.Tyr642Ter)
n.2439T>A
n.2265T>A
c.1728T>A (p.Tyr576Ter)
c.1944T>A (p.Tyr648Ter)
c.1962T>A (p.Tyr654Ter)
17g.42322362T>ACA399581641STAT3c.2021A>T (p.Tyr674Phe)
c.*413A>T (n.*413A>T)
c.1994A>T (p.Tyr665Phe)
n.1474A>T
c.*409A>T (n.*409A>T)
c.2117A>T (p.Tyr706Phe)
n.2221A>T
c.2000A>T (p.Tyr667Phe)
c.1937A>T (p.Tyr646Phe)
c.2036A>T (p.Tyr679Phe)
n.2458A>T
c.1925A>T (p.Tyr642Phe)
n.2438A>T
n.2264A>T
c.1727A>T (p.Tyr576Phe)
c.1943A>T (p.Tyr648Phe)
c.1961A>T (p.Tyr654Phe)
17g.42322362T>CCA399581645STAT3c.2021A>G (p.Tyr674Cys)
c.*413A>G (n.*413A>G)
c.1994A>G (p.Tyr665Cys)
n.1474A>G
c.*409A>G (n.*409A>G)
c.2117A>G (p.Tyr706Cys)
n.2221A>G
c.2000A>G (p.Tyr667Cys)
c.1937A>G (p.Tyr646Cys)
c.2036A>G (p.Tyr679Cys)
n.2458A>G
c.1925A>G (p.Tyr642Cys)
n.2438A>G
n.2264A>G
c.1727A>G (p.Tyr576Cys)
c.1943A>G (p.Tyr648Cys)
c.1961A>G (p.Tyr654Cys)
17g.42322362T>GCA399581647STAT3c.2021A>C (p.Tyr674Ser)
c.*413A>C (n.*413A>C)
c.1994A>C (p.Tyr665Ser)
n.1474A>C
c.*409A>C (n.*409A>C)
c.2117A>C (p.Tyr706Ser)
n.2221A>C
c.2000A>C (p.Tyr667Ser)
c.1937A>C (p.Tyr646Ser)
c.2036A>C (p.Tyr679Ser)
n.2458A>C
c.1925A>C (p.Tyr642Ser)
n.2438A>C
n.2264A>C
c.1727A>C (p.Tyr576Ser)
c.1943A>C (p.Tyr648Ser)
c.1961A>C (p.Tyr654Ser)
17g.42322363A>CCA399581657STAT3c.2020T>G (p.Tyr674Asp)
c.*412T>G (n.*412T>G)
c.1993T>G (p.Tyr665Asp)
n.1473T>G
c.*408T>G (n.*408T>G)
c.2116T>G (p.Tyr706Asp)
n.2220T>G
c.1999T>G (p.Tyr667Asp)
c.1936T>G (p.Tyr646Asp)
c.2035T>G (p.Tyr679Asp)
n.2457T>G
c.1924T>G (p.Tyr642Asp)
n.2437T>G
n.2263T>G
c.1726T>G (p.Tyr576Asp)
c.1942T>G (p.Tyr648Asp)
c.1960T>G (p.Tyr654Asp)
17g.42322363A>GCA399581654STAT3c.2020T>C (p.Tyr674His)
c.*412T>C (n.*412T>C)
c.1993T>C (p.Tyr665His)
n.1473T>C
c.*408T>C (n.*408T>C)
c.2116T>C (p.Tyr706His)
n.2220T>C
c.1999T>C (p.Tyr667His)
c.1936T>C (p.Tyr646His)
c.2035T>C (p.Tyr679His)
n.2457T>C
c.1924T>C (p.Tyr642His)
n.2437T>C
n.2263T>C
c.1726T>C (p.Tyr576His)
c.1942T>C (p.Tyr648His)
c.1960T>C (p.Tyr654His)
17g.42322363A>TCA399581651STAT3c.2020T>A (p.Tyr674Asn)
c.*412T>A (n.*412T>A)
c.1993T>A (p.Tyr665Asn)
n.1473T>A
c.*408T>A (n.*408T>A)
c.2116T>A (p.Tyr706Asn)
n.2220T>A
c.1999T>A (p.Tyr667Asn)
c.1936T>A (p.Tyr646Asn)
c.2035T>A (p.Tyr679Asn)
n.2457T>A
c.1924T>A (p.Tyr642Asn)
n.2437T>A
n.2263T>A
c.1726T>A (p.Tyr576Asn)
c.1942T>A (p.Tyr648Asn)
c.1960T>A (p.Tyr654Asn)
 dbSNP
17g.42322364G>ACA500061046STAT3c.2019C>T (p.Leu673=)
c.*411C>T (n.*411C>T)
c.1992C>T (p.Leu664=)
n.1472C>T
c.*407C>T (n.*407C>T)
c.2115C>T (p.Leu705=)
n.2219C>T
c.1998C>T (p.Leu666=)
c.1935C>T (p.Leu645=)
c.2034C>T (p.Leu678=)
n.2456C>T
c.1923C>T (p.Leu641=)
n.2436C>T
n.2262C>T
c.1725C>T (p.Leu575=)
c.1941C>T (p.Leu647=)
c.1959C>T (p.Leu653=)
 gnomAD v4
17g.42322364G>CCA500061045STAT3c.2019C>G (p.Leu673=)
c.*411C>G (n.*411C>G)
c.1992C>G (p.Leu664=)
n.1472C>G
c.*407C>G (n.*407C>G)
c.2115C>G (p.Leu705=)
n.2219C>G
c.1998C>G (p.Leu666=)
c.1935C>G (p.Leu645=)
c.2034C>G (p.Leu678=)
n.2456C>G
c.1923C>G (p.Leu641=)
n.2436C>G
n.2262C>G
c.1725C>G (p.Leu575=)
c.1941C>G (p.Leu647=)
c.1959C>G (p.Leu653=)
 dbSNP
17g.42322364G>TCA500061044STAT3c.2019C>A (p.Leu673=)
c.*411C>A (n.*411C>A)
c.1992C>A (p.Leu664=)
n.1472C>A
c.*407C>A (n.*407C>A)
c.2115C>A (p.Leu705=)
n.2219C>A
c.1998C>A (p.Leu666=)
c.1935C>A (p.Leu645=)
c.2034C>A (p.Leu678=)
n.2456C>A
c.1923C>A (p.Leu641=)
n.2436C>A
n.2262C>A
c.1725C>A (p.Leu575=)
c.1941C>A (p.Leu647=)
c.1959C>A (p.Leu653=)
 dbSNP
17g.42322365A>CCA399581660STAT3c.2018T>G (p.Leu673Arg)
c.*410T>G (n.*410T>G)
c.1991T>G (p.Leu664Arg)
n.1471T>G
c.*406T>G (n.*406T>G)
c.2114T>G (p.Leu705Arg)
n.2218T>G
c.1997T>G (p.Leu666Arg)
c.1934T>G (p.Leu645Arg)
c.2033T>G (p.Leu678Arg)
n.2455T>G
c.1922T>G (p.Leu641Arg)
n.2435T>G
n.2261T>G
c.1724T>G (p.Leu575Arg)
c.1940T>G (p.Leu647Arg)
c.1958T>G (p.Leu653Arg)
17g.42322365A>GCA399581663STAT3c.2018T>C (p.Leu673Pro)
c.*410T>C (n.*410T>C)
c.1991T>C (p.Leu664Pro)
n.1471T>C
c.*406T>C (n.*406T>C)
c.2114T>C (p.Leu705Pro)
n.2218T>C
c.1997T>C (p.Leu666Pro)
c.1934T>C (p.Leu645Pro)
c.2033T>C (p.Leu678Pro)
n.2455T>C
c.1922T>C (p.Leu641Pro)
n.2435T>C
n.2261T>C
c.1724T>C (p.Leu575Pro)
c.1940T>C (p.Leu647Pro)
c.1958T>C (p.Leu653Pro)
 dbSNP
17g.42322365A>TCA399581665STAT3c.2018T>A (p.Leu673His)
c.*410T>A (n.*410T>A)
c.1991T>A (p.Leu664His)
n.1471T>A
c.*406T>A (n.*406T>A)
c.2114T>A (p.Leu705His)
n.2218T>A
c.1997T>A (p.Leu666His)
c.1934T>A (p.Leu645His)
c.2033T>A (p.Leu678His)
n.2455T>A
c.1922T>A (p.Leu641His)
n.2435T>A
n.2261T>A
c.1724T>A (p.Leu575His)
c.1940T>A (p.Leu647His)
c.1958T>A (p.Leu653His)
 dbSNP
17g.42322366G>ACA399581669STAT3c.2017C>T (p.Leu673Phe)
c.*409C>T (n.*409C>T)
c.1990C>T (p.Leu664Phe)
n.1470C>T
c.*405C>T (n.*405C>T)
c.2113C>T (p.Leu705Phe)
n.2217C>T
c.1996C>T (p.Leu666Phe)
c.1933C>T (p.Leu645Phe)
c.2032C>T (p.Leu678Phe)
n.2454C>T
c.1921C>T (p.Leu641Phe)
n.2434C>T
n.2260C>T
c.1723C>T (p.Leu575Phe)
c.1939C>T (p.Leu647Phe)
c.1957C>T (p.Leu653Phe)
 gnomAD v4
17g.42322366G>CCA399581672STAT3c.2017C>G (p.Leu673Val)
c.*409C>G (n.*409C>G)
c.1990C>G (p.Leu664Val)
n.1470C>G
c.*405C>G (n.*405C>G)
c.2113C>G (p.Leu705Val)
n.2217C>G
c.1996C>G (p.Leu666Val)
c.1933C>G (p.Leu645Val)
c.2032C>G (p.Leu678Val)
n.2454C>G
c.1921C>G (p.Leu641Val)
n.2434C>G
n.2260C>G
c.1723C>G (p.Leu575Val)
c.1939C>G (p.Leu647Val)
c.1957C>G (p.Leu653Val)
 dbSNP
17g.42322366G>TCA399581675STAT3c.2017C>A (p.Leu673Ile)
c.*409C>A (n.*409C>A)
c.1990C>A (p.Leu664Ile)
n.1470C>A
c.*405C>A (n.*405C>A)
c.2113C>A (p.Leu705Ile)
n.2217C>A
c.1996C>A (p.Leu666Ile)
c.1933C>A (p.Leu645Ile)
c.2032C>A (p.Leu678Ile)
n.2454C>A
c.1921C>A (p.Leu641Ile)
n.2434C>A
n.2260C>A
c.1723C>A (p.Leu575Ile)
c.1939C>A (p.Leu647Ile)
c.1957C>A (p.Leu653Ile)
17g.42322367A>CCA399581677STAT3c.2016T>G (p.Tyr672Ter)
c.*408T>G (n.*408T>G)
c.1989T>G (p.Tyr663Ter)
n.1469T>G
c.*404T>G (n.*404T>G)
c.2112T>G (p.Tyr704Ter)
n.2216T>G
c.1995T>G (p.Tyr665Ter)
c.1932T>G (p.Tyr644Ter)
c.2031T>G (p.Tyr677Ter)
n.2453T>G
c.1920T>G (p.Tyr640Ter)
n.2433T>G
n.2259T>G
c.1722T>G (p.Tyr574Ter)
c.1938T>G (p.Tyr646Ter)
c.1956T>G (p.Tyr652Ter)
17g.42322367A>GCA500061047STAT3c.2016T>C (p.Tyr672=)
c.*408T>C (n.*408T>C)
c.1989T>C (p.Tyr663=)
n.1469T>C
c.*404T>C (n.*404T>C)
c.2112T>C (p.Tyr704=)
n.2216T>C
c.1995T>C (p.Tyr665=)
c.1932T>C (p.Tyr644=)
c.2031T>C (p.Tyr677=)
n.2453T>C
c.1920T>C (p.Tyr640=)
n.2433T>C
n.2259T>C
c.1722T>C (p.Tyr574=)
c.1938T>C (p.Tyr646=)
c.1956T>C (p.Tyr652=)
17g.42322367A>TCA399581680STAT3c.2016T>A (p.Tyr672Ter)
c.*408T>A (n.*408T>A)
c.1989T>A (p.Tyr663Ter)
n.1469T>A
c.*404T>A (n.*404T>A)
c.2112T>A (p.Tyr704Ter)
n.2216T>A
c.1995T>A (p.Tyr665Ter)
c.1932T>A (p.Tyr644Ter)
c.2031T>A (p.Tyr677Ter)
n.2453T>A
c.1920T>A (p.Tyr640Ter)
n.2433T>A
n.2259T>A
c.1722T>A (p.Tyr574Ter)
c.1938T>A (p.Tyr646Ter)
c.1956T>A (p.Tyr652Ter)
17g.42322368T>ACA399581683STAT3c.2015A>T (p.Tyr672Phe)
c.*407A>T (n.*407A>T)
c.1988A>T (p.Tyr663Phe)
n.1468A>T
c.*403A>T (n.*403A>T)
c.2111A>T (p.Tyr704Phe)
n.2215A>T
c.1994A>T (p.Tyr665Phe)
c.1931A>T (p.Tyr644Phe)
c.2030A>T (p.Tyr677Phe)
n.2452A>T
c.1919A>T (p.Tyr640Phe)
n.2432A>T
n.2258A>T
c.1721A>T (p.Tyr574Phe)
c.1937A>T (p.Tyr646Phe)
c.1955A>T (p.Tyr652Phe)
 dbSNP gnomAD v2
17g.42322368T>CCA399581684STAT3c.2015A>G (p.Tyr672Cys)
c.*407A>G (n.*407A>G)
c.1988A>G (p.Tyr663Cys)
n.1468A>G
c.*403A>G (n.*403A>G)
c.2111A>G (p.Tyr704Cys)
n.2215A>G
c.1994A>G (p.Tyr665Cys)
c.1931A>G (p.Tyr644Cys)
c.2030A>G (p.Tyr677Cys)
n.2452A>G
c.1919A>G (p.Tyr640Cys)
n.2432A>G
n.2258A>G
c.1721A>G (p.Tyr574Cys)
c.1937A>G (p.Tyr646Cys)
c.1955A>G (p.Tyr652Cys)
 ClinVar dbSNP gnomAD v4
17g.42322368T>GCA399581686STAT3c.2015A>C (p.Tyr672Ser)
c.*407A>C (n.*407A>C)
c.1988A>C (p.Tyr663Ser)
n.1468A>C
c.*403A>C (n.*403A>C)
c.2111A>C (p.Tyr704Ser)
n.2215A>C
c.1994A>C (p.Tyr665Ser)
c.1931A>C (p.Tyr644Ser)
c.2030A>C (p.Tyr677Ser)
n.2452A>C
c.1919A>C (p.Tyr640Ser)
n.2432A>C
n.2258A>C
c.1721A>C (p.Tyr574Ser)
c.1937A>C (p.Tyr646Ser)
c.1955A>C (p.Tyr652Ser)
17g.42322368T=CA2260430717STAT3c.2015A= (p.Tyr672=)
c.*407A= (n.*407A=)
c.1988A= (p.Tyr663=)
n.1468A=
c.*403A= (n.*403A=)
c.2111A= (p.Tyr704=)
n.2215A=
c.1994A= (p.Tyr665=)
c.1931A= (p.Tyr644=)
c.2030A= (p.Tyr677=)
n.2452A=
c.1919A= (p.Tyr640=)
n.2432A=
n.2258A=
c.1721A= (p.Tyr574=)
c.1937A= (p.Tyr646=)
c.1955A= (p.Tyr652=)
17g.42322369A>CCA399581689STAT3c.2014T>G (p.Tyr672Asp)
c.*406T>G (n.*406T>G)
c.1987T>G (p.Tyr663Asp)
n.1467T>G
c.*402T>G (n.*402T>G)
c.2110T>G (p.Tyr704Asp)
n.2214T>G
c.1993T>G (p.Tyr665Asp)
c.1930T>G (p.Tyr644Asp)
c.2029T>G (p.Tyr677Asp)
n.2451T>G
c.1918T>G (p.Tyr640Asp)
n.2431T>G
n.2257T>G
c.1720T>G (p.Tyr574Asp)
c.1936T>G (p.Tyr646Asp)
c.1954T>G (p.Tyr652Asp)
17g.42322369A>GCA399581692STAT3c.2014T>C (p.Tyr672His)
c.*406T>C (n.*406T>C)
c.1987T>C (p.Tyr663His)
n.1467T>C
c.*402T>C (n.*402T>C)
c.2110T>C (p.Tyr704His)
n.2214T>C
c.1993T>C (p.Tyr665His)
c.1930T>C (p.Tyr644His)
c.2029T>C (p.Tyr677His)
n.2451T>C
c.1918T>C (p.Tyr640His)
n.2431T>C
n.2257T>C
c.1720T>C (p.Tyr574His)
c.1936T>C (p.Tyr646His)
c.1954T>C (p.Tyr652His)
 dbSNP gnomAD v4
17g.42322369A>TCA399581695STAT3c.2014T>A (p.Tyr672Asn)
c.*406T>A (n.*406T>A)
c.1987T>A (p.Tyr663Asn)
n.1467T>A
c.*402T>A (n.*402T>A)
c.2110T>A (p.Tyr704Asn)
n.2214T>A
c.1993T>A (p.Tyr665Asn)
c.1930T>A (p.Tyr644Asn)
c.2029T>A (p.Tyr677Asn)
n.2451T>A
c.1918T>A (p.Tyr640Asn)
n.2431T>A
n.2257T>A
c.1720T>A (p.Tyr574Asn)
c.1936T>A (p.Tyr646Asn)
c.1954T>A (p.Tyr652Asn)
 dbSNP
17g.42322370G>ACA500061050STAT3c.2013C>T (p.Val671=)
c.*405C>T (n.*405C>T)
c.1986C>T (p.Val662=)
n.1466C>T
c.*401C>T (n.*401C>T)
c.2109C>T (p.Val703=)
n.2213C>T
c.1992C>T (p.Val664=)
c.1929C>T (p.Val643=)
c.2028C>T (p.Val676=)
n.2450C>T
c.1917C>T (p.Val639=)
n.2430C>T
n.2256C>T
c.1719C>T (p.Val573=)
c.1935C>T (p.Val645=)
c.1953C>T (p.Val651=)
 dbSNP gnomAD v4
17g.42322370G>CCA500061051STAT3c.2013C>G (p.Val671=)
c.*405C>G (n.*405C>G)
c.1986C>G (p.Val662=)
n.1466C>G
c.*401C>G (n.*401C>G)
c.2109C>G (p.Val703=)
n.2213C>G
c.1992C>G (p.Val664=)
c.1929C>G (p.Val643=)
c.2028C>G (p.Val676=)
n.2450C>G
c.1917C>G (p.Val639=)
n.2430C>G
n.2256C>G
c.1719C>G (p.Val573=)
c.1935C>G (p.Val645=)
c.1953C>G (p.Val651=)
 dbSNP
17g.42322370G>TCA500061052STAT3c.2013C>A (p.Val671=)
c.*405C>A (n.*405C>A)
c.1986C>A (p.Val662=)
n.1466C>A
c.*401C>A (n.*401C>A)
c.2109C>A (p.Val703=)
n.2213C>A
c.1992C>A (p.Val664=)
c.1929C>A (p.Val643=)
c.2028C>A (p.Val676=)
n.2450C>A
c.1917C>A (p.Val639=)
n.2430C>A
n.2256C>A
c.1719C>A (p.Val573=)
c.1935C>A (p.Val645=)
c.1953C>A (p.Val651=)
17g.42322371A>CCA399581700STAT3c.2012T>G (p.Val671Gly)
c.*404T>G (n.*404T>G)
c.1985T>G (p.Val662Gly)
n.1465T>G
c.*400T>G (n.*400T>G)
c.2108T>G (p.Val703Gly)
n.2212T>G
c.1991T>G (p.Val664Gly)
c.1928T>G (p.Val643Gly)
c.2027T>G (p.Val676Gly)
n.2449T>G
c.1916T>G (p.Val639Gly)
n.2429T>G
n.2255T>G
c.1718T>G (p.Val573Gly)
c.1934T>G (p.Val645Gly)
c.1952T>G (p.Val651Gly)
17g.42322371A>GCA399581701STAT3c.2012T>C (p.Val671Ala)
c.*404T>C (n.*404T>C)
c.1985T>C (p.Val662Ala)
n.1465T>C
c.*400T>C (n.*400T>C)
c.2108T>C (p.Val703Ala)
n.2212T>C
c.1991T>C (p.Val664Ala)
c.1928T>C (p.Val643Ala)
c.2027T>C (p.Val676Ala)
n.2449T>C
c.1916T>C (p.Val639Ala)
n.2429T>C
n.2255T>C
c.1718T>C (p.Val573Ala)
c.1934T>C (p.Val645Ala)
c.1952T>C (p.Val651Ala)
 dbSNP
17g.42322371A>TCA399581698STAT3c.2012T>A (p.Val671Asp)
c.*404T>A (n.*404T>A)
c.1985T>A (p.Val662Asp)
n.1465T>A
c.*400T>A (n.*400T>A)
c.2108T>A (p.Val703Asp)
n.2212T>A
c.1991T>A (p.Val664Asp)
c.1928T>A (p.Val643Asp)
c.2027T>A (p.Val676Asp)
n.2449T>A
c.1916T>A (p.Val639Asp)
n.2429T>A
n.2255T>A
c.1718T>A (p.Val573Asp)
c.1934T>A (p.Val645Asp)
c.1952T>A (p.Val651Asp)
 dbSNP
17g.42322372C>ACA399581704STAT3c.2011G>T (p.Val671Phe)
c.*403G>T (n.*403G>T)
c.1984G>T (p.Val662Phe)
n.1464G>T
c.*399G>T (n.*399G>T)
c.2107G>T (p.Val703Phe)
n.2211G>T
c.1990G>T (p.Val664Phe)
c.1927G>T (p.Val643Phe)
c.2026G>T (p.Val676Phe)
n.2448G>T
c.1915G>T (p.Val639Phe)
n.2428G>T
n.2254G>T
c.1717G>T (p.Val573Phe)
c.1933G>T (p.Val645Phe)
c.1951G>T (p.Val651Phe)
 dbSNP
17g.42322372C>GCA399581707STAT3c.2011G>C (p.Val671Leu)
c.*403G>C (n.*403G>C)
c.1984G>C (p.Val662Leu)
n.1464G>C
c.*399G>C (n.*399G>C)
c.2107G>C (p.Val703Leu)
n.2211G>C
c.1990G>C (p.Val664Leu)
c.1927G>C (p.Val643Leu)
c.2026G>C (p.Val676Leu)
n.2448G>C
c.1915G>C (p.Val639Leu)
n.2428G>C
n.2254G>C
c.1717G>C (p.Val573Leu)
c.1933G>C (p.Val645Leu)
c.1951G>C (p.Val651Leu)
 dbSNP
17g.42322372C>TCA399581710STAT3c.2011G>A (p.Val671Ile)
c.*403G>A (n.*403G>A)
c.1984G>A (p.Val662Ile)
n.1464G>A
c.*399G>A (n.*399G>A)
c.2107G>A (p.Val703Ile)
n.2211G>A
c.1990G>A (p.Val664Ile)
c.1927G>A (p.Val643Ile)
c.2026G>A (p.Val676Ile)
n.2448G>A
c.1915G>A (p.Val639Ile)
n.2428G>A
n.2254G>A
c.1717G>A (p.Val573Ile)
c.1933G>A (p.Val645Ile)
c.1951G>A (p.Val651Ile)
 dbSNP
17g.42322373C>ACA500061055STAT3c.2010G>T (p.Leu670=)
c.*402G>T (n.*402G>T)
c.1983G>T (p.Leu661=)
n.1463G>T
c.*398G>T (n.*398G>T)
c.2106G>T (p.Leu702=)
n.2210G>T
c.1989G>T (p.Leu663=)
c.1926G>T (p.Leu642=)
c.2025G>T (p.Leu675=)
n.2447G>T
c.1914G>T (p.Leu638=)
n.2427G>T
n.2253G>T
c.1716G>T (p.Leu572=)
c.1932G>T (p.Leu644=)
c.1950G>T (p.Leu650=)
 dbSNP
17g.42322373C>GCA500061053STAT3c.2010G>C (p.Leu670=)
c.*402G>C (n.*402G>C)
c.1983G>C (p.Leu661=)
n.1463G>C
c.*398G>C (n.*398G>C)
c.2106G>C (p.Leu702=)
n.2210G>C
c.1989G>C (p.Leu663=)
c.1926G>C (p.Leu642=)
c.2025G>C (p.Leu675=)
n.2447G>C
c.1914G>C (p.Leu638=)
n.2427G>C
n.2253G>C
c.1716G>C (p.Leu572=)
c.1932G>C (p.Leu644=)
c.1950G>C (p.Leu650=)
 dbSNP
17g.42322373C>TCA500061054STAT3c.2010G>A (p.Leu670=)
c.*402G>A (n.*402G>A)
c.1983G>A (p.Leu661=)
n.1463G>A
c.*398G>A (n.*398G>A)
c.2106G>A (p.Leu702=)
n.2210G>A
c.1989G>A (p.Leu663=)
c.1926G>A (p.Leu642=)
c.2025G>A (p.Leu675=)
n.2447G>A
c.1914G>A (p.Leu638=)
n.2427G>A
n.2253G>A
c.1716G>A (p.Leu572=)
c.1932G>A (p.Leu644=)
c.1950G>A (p.Leu650=)
 dbSNP
17g.42322374A>CCA399581712STAT3c.2009T>G (p.Leu670Arg)
c.*401T>G (n.*401T>G)
c.1982T>G (p.Leu661Arg)
n.1462T>G
c.*397T>G (n.*397T>G)
c.2105T>G (p.Leu702Arg)
n.2209T>G
c.1988T>G (p.Leu663Arg)
c.1925T>G (p.Leu642Arg)
c.2024T>G (p.Leu675Arg)
n.2446T>G
c.1913T>G (p.Leu638Arg)
n.2426T>G
n.2252T>G
c.1715T>G (p.Leu572Arg)
c.1931T>G (p.Leu644Arg)
c.1949T>G (p.Leu650Arg)
17g.42322374A>GCA399581714STAT3c.2009T>C (p.Leu670Pro)
c.*401T>C (n.*401T>C)
c.1982T>C (p.Leu661Pro)
n.1462T>C
c.*397T>C (n.*397T>C)
c.2105T>C (p.Leu702Pro)
n.2209T>C
c.1988T>C (p.Leu663Pro)
c.1925T>C (p.Leu642Pro)
c.2024T>C (p.Leu675Pro)
n.2446T>C
c.1913T>C (p.Leu638Pro)
n.2426T>C
n.2252T>C
c.1715T>C (p.Leu572Pro)
c.1931T>C (p.Leu644Pro)
c.1949T>C (p.Leu650Pro)
17g.42322374A>TCA399581716STAT3c.2009T>A (p.Leu670Gln)
c.*401T>A (n.*401T>A)
c.1982T>A (p.Leu661Gln)
n.1462T>A
c.*397T>A (n.*397T>A)
c.2105T>A (p.Leu702Gln)
n.2209T>A
c.1988T>A (p.Leu663Gln)
c.1925T>A (p.Leu642Gln)
c.2024T>A (p.Leu675Gln)
n.2446T>A
c.1913T>A (p.Leu638Gln)
n.2426T>A
n.2252T>A
c.1715T>A (p.Leu572Gln)
c.1931T>A (p.Leu644Gln)
c.1949T>A (p.Leu650Gln)
 dbSNP
17g.42322375G>ACA500061056STAT3c.2008C>T (p.Leu670=)
c.*400C>T (n.*400C>T)
c.1981C>T (p.Leu661=)
n.1461C>T
c.*396C>T (n.*396C>T)
c.2104C>T (p.Leu702=)
n.2208C>T
c.1987C>T (p.Leu663=)
c.1924C>T (p.Leu642=)
c.2023C>T (p.Leu675=)
n.2445C>T
c.1912C>T (p.Leu638=)
n.2425C>T
n.2251C>T
c.1714C>T (p.Leu572=)
c.1930C>T (p.Leu644=)
c.1948C>T (p.Leu650=)
 dbSNP gnomAD v4
17g.42322375G>CCA399581722STAT3c.2008C>G (p.Leu670Val)
c.*400C>G (n.*400C>G)
c.1981C>G (p.Leu661Val)
n.1461C>G
c.*396C>G (n.*396C>G)
c.2104C>G (p.Leu702Val)
n.2208C>G
c.1987C>G (p.Leu663Val)
c.1924C>G (p.Leu642Val)
c.2023C>G (p.Leu675Val)
n.2445C>G
c.1912C>G (p.Leu638Val)
n.2425C>G
n.2251C>G
c.1714C>G (p.Leu572Val)
c.1930C>G (p.Leu644Val)
c.1948C>G (p.Leu650Val)
 dbSNP
17g.42322375G>TCA399581725STAT3c.2008C>A (p.Leu670Met)
c.*400C>A (n.*400C>A)
c.1981C>A (p.Leu661Met)
n.1461C>A
c.*396C>A (n.*396C>A)
c.2104C>A (p.Leu702Met)
n.2208C>A
c.1987C>A (p.Leu663Met)
c.1924C>A (p.Leu642Met)
c.2023C>A (p.Leu675Met)
n.2445C>A
c.1912C>A (p.Leu638Met)
n.2425C>A
n.2251C>A
c.1714C>A (p.Leu572Met)
c.1930C>A (p.Leu644Met)
c.1948C>A (p.Leu650Met)
17g.42322376T>ACA500061058STAT3c.2007A>T (p.Pro669=)
c.*399A>T (n.*399A>T)
c.1980A>T (p.Pro660=)
n.1460A>T
c.*395A>T (n.*395A>T)
c.2103A>T (p.Pro701=)
n.2207A>T
c.1986A>T (p.Pro662=)
c.1923A>T (p.Pro641=)
c.2022A>T (p.Pro674=)
n.2444A>T
c.1911A>T (p.Pro637=)
n.2424A>T
n.2250A>T
c.1713A>T (p.Pro571=)
c.1929A>T (p.Pro643=)
c.1947A>T (p.Pro649=)
17g.42322376T>CCA500061059STAT3c.2007A>G (p.Pro669=)
c.*399A>G (n.*399A>G)
c.1980A>G (p.Pro660=)
n.1460A>G
c.*395A>G (n.*395A>G)
c.2103A>G (p.Pro701=)
n.2207A>G
c.1986A>G (p.Pro662=)
c.1923A>G (p.Pro641=)
c.2022A>G (p.Pro674=)
n.2444A>G
c.1911A>G (p.Pro637=)
n.2424A>G
n.2250A>G
c.1713A>G (p.Pro571=)
c.1929A>G (p.Pro643=)
c.1947A>G (p.Pro649=)
17g.42322376T>GCA500061057STAT3c.2007A>C (p.Pro669=)
c.*399A>C (n.*399A>C)
c.1980A>C (p.Pro660=)
n.1460A>C
c.*395A>C (n.*395A>C)
c.2103A>C (p.Pro701=)
n.2207A>C
c.1986A>C (p.Pro662=)
c.1923A>C (p.Pro641=)
c.2022A>C (p.Pro674=)
n.2444A>C
c.1911A>C (p.Pro637=)
n.2424A>C
n.2250A>C
c.1713A>C (p.Pro571=)
c.1929A>C (p.Pro643=)
c.1947A>C (p.Pro649=)
 ClinVar
17g.42322377G>ACA399581728STAT3c.2006C>T (p.Pro669Leu)
c.*398C>T (n.*398C>T)
c.1979C>T (p.Pro660Leu)
n.1459C>T
c.*394C>T (n.*394C>T)
c.2102C>T (p.Pro701Leu)
n.2206C>T
c.1985C>T (p.Pro662Leu)
c.1922C>T (p.Pro641Leu)
c.2021C>T (p.Pro674Leu)
n.2443C>T
c.1910C>T (p.Pro637Leu)
n.2423C>T
n.2249C>T
c.1712C>T (p.Pro571Leu)
c.1928C>T (p.Pro643Leu)
c.1946C>T (p.Pro649Leu)
 dbSNP
17g.42322377G>CCA399581730STAT3c.2006C>G (p.Pro669Arg)
c.*398C>G (n.*398C>G)
c.1979C>G (p.Pro660Arg)
n.1459C>G
c.*394C>G (n.*394C>G)
c.2102C>G (p.Pro701Arg)
n.2206C>G
c.1985C>G (p.Pro662Arg)
c.1922C>G (p.Pro641Arg)
c.2021C>G (p.Pro674Arg)
n.2443C>G
c.1910C>G (p.Pro637Arg)
n.2423C>G
n.2249C>G
c.1712C>G (p.Pro571Arg)
c.1928C>G (p.Pro643Arg)
c.1946C>G (p.Pro649Arg)
 dbSNP
17g.42322377G>TCA399581732STAT3c.2006C>A (p.Pro669Gln)
c.*398C>A (n.*398C>A)
c.1979C>A (p.Pro660Gln)
n.1459C>A
c.*394C>A (n.*394C>A)
c.2102C>A (p.Pro701Gln)
n.2206C>A
c.1985C>A (p.Pro662Gln)
c.1922C>A (p.Pro641Gln)
c.2021C>A (p.Pro674Gln)
n.2443C>A
c.1910C>A (p.Pro637Gln)
n.2423C>A
n.2249C>A
c.1712C>A (p.Pro571Gln)
c.1928C>A (p.Pro643Gln)
c.1946C>A (p.Pro649Gln)
 dbSNP
17g.42322378G>ACA399581735STAT3c.2005C>T (p.Pro669Ser)
c.*397C>T (n.*397C>T)
c.1978C>T (p.Pro660Ser)
n.1458C>T
c.*393C>T (n.*393C>T)
c.2101C>T (p.Pro701Ser)
n.2205C>T
c.1984C>T (p.Pro662Ser)
c.1921C>T (p.Pro641Ser)
c.2020C>T (p.Pro674Ser)
n.2442C>T
c.1909C>T (p.Pro637Ser)
n.2422C>T
n.2248C>T
c.1711C>T (p.Pro571Ser)
c.1927C>T (p.Pro643Ser)
c.1945C>T (p.Pro649Ser)
 ClinVar dbSNP
17g.42322378G>CCA399581736STAT3c.2005C>G (p.Pro669Ala)
c.*397C>G (n.*397C>G)
c.1978C>G (p.Pro660Ala)
n.1458C>G
c.*393C>G (n.*393C>G)
c.2101C>G (p.Pro701Ala)
n.2205C>G
c.1984C>G (p.Pro662Ala)
c.1921C>G (p.Pro641Ala)
c.2020C>G (p.Pro674Ala)
n.2442C>G
c.1909C>G (p.Pro637Ala)
n.2422C>G
n.2248C>G
c.1711C>G (p.Pro571Ala)
c.1927C>G (p.Pro643Ala)
c.1945C>G (p.Pro649Ala)
 dbSNP
17g.42322378G>TCA399581737STAT3c.2005C>A (p.Pro669Thr)
c.*397C>A (n.*397C>A)
c.1978C>A (p.Pro660Thr)
n.1458C>A
c.*393C>A (n.*393C>A)
c.2101C>A (p.Pro701Thr)
n.2205C>A
c.1984C>A (p.Pro662Thr)
c.1921C>A (p.Pro641Thr)
c.2020C>A (p.Pro674Thr)
n.2442C>A
c.1909C>A (p.Pro637Thr)
n.2422C>A
n.2248C>A
c.1711C>A (p.Pro571Thr)
c.1927C>A (p.Pro643Thr)
c.1945C>A (p.Pro649Thr)
 dbSNP
17g.42322379A=CA2260430718STAT3c.2004T= (p.Ser668=)
c.*396T= (n.*396T=)
c.1977T= (p.Ser659=)
n.1457T=
c.*392T= (n.*392T=)
c.2100T= (p.Ser700=)
n.2204T=
c.1983T= (p.Ser661=)
c.1920T= (p.Ser640=)
c.2019T= (p.Ser673=)
n.2441T=
c.1908T= (p.Ser636=)
n.2421T=
n.2247T=
c.1710T= (p.Ser570=)
c.1926T= (p.Ser642=)
c.1944T= (p.Ser648=)
17g.42322379A>CCA500061060STAT3c.2004T>G (p.Ser668=)
c.*396T>G (n.*396T>G)
c.1977T>G (p.Ser659=)
n.1457T>G
c.*392T>G (n.*392T>G)
c.2100T>G (p.Ser700=)
n.2204T>G
c.1983T>G (p.Ser661=)
c.1920T>G (p.Ser640=)
c.2019T>G (p.Ser673=)
n.2441T>G
c.1908T>G (p.Ser636=)
n.2421T>G
n.2247T>G
c.1710T>G (p.Ser570=)
c.1926T>G (p.Ser642=)
c.1944T>G (p.Ser648=)
17g.42322379A>GCA8575177STAT3c.2004T>C (p.Ser668=)
c.*396T>C (n.*396T>C)
c.1977T>C (p.Ser659=)
n.1457T>C
c.*392T>C (n.*392T>C)
c.2100T>C (p.Ser700=)
n.2204T>C
c.1983T>C (p.Ser661=)
c.1920T>C (p.Ser640=)
c.2019T>C (p.Ser673=)
n.2441T>C
c.1908T>C (p.Ser636=)
n.2421T>C
n.2247T>C
c.1710T>C (p.Ser570=)
c.1926T>C (p.Ser642=)
c.1944T>C (p.Ser648=)
 dbSNP ExAC gnomAD v2 gnomAD v4
17g.42322379A>TCA500061061STAT3c.2004T>A (p.Ser668=)
c.*396T>A (n.*396T>A)
c.1977T>A (p.Ser659=)
n.1457T>A
c.*392T>A (n.*392T>A)
c.2100T>A (p.Ser700=)
n.2204T>A
c.1983T>A (p.Ser661=)
c.1920T>A (p.Ser640=)
c.2019T>A (p.Ser673=)
n.2441T>A
c.1908T>A (p.Ser636=)
n.2421T>A
n.2247T>A
c.1710T>A (p.Ser570=)
c.1926T>A (p.Ser642=)
c.1944T>A (p.Ser648=)
 dbSNP
17g.42322380G>ACA399581738STAT3c.2003C>T (p.Ser668Phe)
c.*395C>T (n.*395C>T)
c.1976C>T (p.Ser659Phe)
n.1456C>T
c.*391C>T (n.*391C>T)
c.2099C>T (p.Ser700Phe)
n.2203C>T
c.1982C>T (p.Ser661Phe)
c.1919C>T (p.Ser640Phe)
c.2018C>T (p.Ser673Phe)
n.2440C>T
c.1907C>T (p.Ser636Phe)
n.2420C>T
n.2246C>T
c.1709C>T (p.Ser570Phe)
c.1925C>T (p.Ser642Phe)
c.1943C>T (p.Ser648Phe)
 dbSNP
17g.42322380G>CCA399581739STAT3c.2003C>G (p.Ser668Cys)
c.*395C>G (n.*395C>G)
c.1976C>G (p.Ser659Cys)
n.1456C>G
c.*391C>G (n.*391C>G)
c.2099C>G (p.Ser700Cys)
n.2203C>G
c.1982C>G (p.Ser661Cys)
c.1919C>G (p.Ser640Cys)
c.2018C>G (p.Ser673Cys)
n.2440C>G
c.1907C>G (p.Ser636Cys)
n.2420C>G
n.2246C>G
c.1709C>G (p.Ser570Cys)
c.1925C>G (p.Ser642Cys)
c.1943C>G (p.Ser648Cys)
 dbSNP
17g.42322380G>TCA399581741STAT3c.2003C>A (p.Ser668Tyr)
c.*395C>A (n.*395C>A)
c.1976C>A (p.Ser659Tyr)
n.1456C>A
c.*391C>A (n.*391C>A)
c.2099C>A (p.Ser700Tyr)
n.2203C>A
c.1982C>A (p.Ser661Tyr)
c.1919C>A (p.Ser640Tyr)
c.2018C>A (p.Ser673Tyr)
n.2440C>A
c.1907C>A (p.Ser636Tyr)
n.2420C>A
n.2246C>A
c.1709C>A (p.Ser570Tyr)
c.1925C>A (p.Ser642Tyr)
c.1943C>A (p.Ser648Tyr)
17g.42322381A>CCA399581745STAT3c.2002T>G (p.Ser668Ala)
c.*394T>G (n.*394T>G)
c.1975T>G (p.Ser659Ala)
n.1455T>G
c.*390T>G (n.*390T>G)
c.2098T>G (p.Ser700Ala)
n.2202T>G
c.1981T>G (p.Ser661Ala)
c.1918T>G (p.Ser640Ala)
c.2017T>G (p.Ser673Ala)
n.2439T>G
c.1906T>G (p.Ser636Ala)
n.2419T>G
n.2245T>G
c.1708T>G (p.Ser570Ala)
c.1924T>G (p.Ser642Ala)
c.1942T>G (p.Ser648Ala)
17g.42322381A>GCA399581748STAT3c.2002T>C (p.Ser668Pro)
c.*394T>C (n.*394T>C)
c.1975T>C (p.Ser659Pro)
n.1455T>C
c.*390T>C (n.*390T>C)
c.2098T>C (p.Ser700Pro)
n.2202T>C
c.1981T>C (p.Ser661Pro)
c.1918T>C (p.Ser640Pro)
c.2017T>C (p.Ser673Pro)
n.2439T>C
c.1906T>C (p.Ser636Pro)
n.2419T>C
n.2245T>C
c.1708T>C (p.Ser570Pro)
c.1924T>C (p.Ser642Pro)
c.1942T>C (p.Ser648Pro)
 dbSNP
17g.42322381A>TCA399581751STAT3c.2002T>A (p.Ser668Thr)
c.*394T>A (n.*394T>A)
c.1975T>A (p.Ser659Thr)
n.1455T>A
c.*390T>A (n.*390T>A)
c.2098T>A (p.Ser700Thr)
n.2202T>A
c.1981T>A (p.Ser661Thr)
c.1918T>A (p.Ser640Thr)
c.2017T>A (p.Ser673Thr)
n.2439T>A
c.1906T>A (p.Ser636Thr)
n.2419T>A
n.2245T>A
c.1708T>A (p.Ser570Thr)
c.1924T>A (p.Ser642Thr)
c.1942T>A (p.Ser648Thr)
 dbSNP
17g.42322382C>ACA500061062STAT3c.2001G>T (p.Val667=)
c.*393G>T (n.*393G>T)
c.1974G>T (p.Val658=)
n.1454G>T
c.*389G>T (n.*389G>T)
c.2097G>T (p.Val699=)
n.2201G>T
c.1980G>T (p.Val660=)
c.1917G>T (p.Val639=)
c.2016G>T (p.Val672=)
n.2438G>T
c.1905G>T (p.Val635=)
n.2418G>T
n.2244G>T
c.1707G>T (p.Val569=)
c.1923G>T (p.Val641=)
c.1941G>T (p.Val647=)
17g.42322382C>GCA500061065STAT3c.2001G>C (p.Val667=)
c.*393G>C (n.*393G>C)
c.1974G>C (p.Val658=)
n.1454G>C
c.*389G>C (n.*389G>C)
c.2097G>C (p.Val699=)
n.2201G>C
c.1980G>C (p.Val660=)
c.1917G>C (p.Val639=)
c.2016G>C (p.Val672=)
n.2438G>C
c.1905G>C (p.Val635=)
n.2418G>C
n.2244G>C
c.1707G>C (p.Val569=)
c.1923G>C (p.Val641=)
c.1941G>C (p.Val647=)
 dbSNP
17g.42322382C>TCA500061063STAT3c.2001G>A (p.Val667=)
c.*393G>A (n.*393G>A)
c.1974G>A (p.Val658=)
n.1454G>A
c.*389G>A (n.*389G>A)
c.2097G>A (p.Val699=)
n.2201G>A
c.1980G>A (p.Val660=)
c.1917G>A (p.Val639=)
c.2016G>A (p.Val672=)
n.2438G>A
c.1905G>A (p.Val635=)
n.2418G>A
n.2244G>A
c.1707G>A (p.Val569=)
c.1923G>A (p.Val641=)
c.1941G>A (p.Val647=)
 dbSNP
17g.42322383A=CA2260430719STAT3c.2000T= (p.Val667=)
c.*392T= (n.*392T=)
c.1973T= (p.Val658=)
n.1453T=
c.*388T= (n.*388T=)
c.2096T= (p.Val699=)
n.2200T=
c.1979T= (p.Val660=)
c.1916T= (p.Val639=)
c.2015T= (p.Val672=)
n.2437T=
c.1904T= (p.Val635=)
n.2417T=
n.2243T=
c.1706T= (p.Val569=)
c.1922T= (p.Val641=)
c.1940T= (p.Val647=)
17g.42322383A>CCA399581753STAT3c.2000T>G (p.Val667Gly)
c.*392T>G (n.*392T>G)
c.1973T>G (p.Val658Gly)
n.1453T>G
c.*388T>G (n.*388T>G)
c.2096T>G (p.Val699Gly)
n.2200T>G
c.1979T>G (p.Val660Gly)
c.1916T>G (p.Val639Gly)
c.2015T>G (p.Val672Gly)
n.2437T>G
c.1904T>G (p.Val635Gly)
n.2417T>G
n.2243T>G
c.1706T>G (p.Val569Gly)
c.1922T>G (p.Val641Gly)
c.1940T>G (p.Val647Gly)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
17g.42322383A>GCA399581755STAT3c.2000T>C (p.Val667Ala)
c.*392T>C (n.*392T>C)
c.1973T>C (p.Val658Ala)
n.1453T>C
c.*388T>C (n.*388T>C)
c.2096T>C (p.Val699Ala)
n.2200T>C
c.1979T>C (p.Val660Ala)
c.1916T>C (p.Val639Ala)
c.2015T>C (p.Val672Ala)
n.2437T>C
c.1904T>C (p.Val635Ala)
n.2417T>C
n.2243T>C
c.1706T>C (p.Val569Ala)
c.1922T>C (p.Val641Ala)
c.1940T>C (p.Val647Ala)
 dbSNP
17g.42322383A>TCA399581758STAT3c.2000T>A (p.Val667Glu)
c.*392T>A (n.*392T>A)
c.1973T>A (p.Val658Glu)
n.1453T>A
c.*388T>A (n.*388T>A)
c.2096T>A (p.Val699Glu)
n.2200T>A
c.1979T>A (p.Val660Glu)
c.1916T>A (p.Val639Glu)
c.2015T>A (p.Val672Glu)
n.2437T>A
c.1904T>A (p.Val635Glu)
n.2417T>A
n.2243T>A
c.1706T>A (p.Val569Glu)
c.1922T>A (p.Val641Glu)
c.1940T>A (p.Val647Glu)
17g.42322384C>ACA399581762STAT3c.1999G>T (p.Val667Leu)
c.*391G>T (n.*391G>T)
c.1972G>T (p.Val658Leu)
n.1452G>T
c.*387G>T (n.*387G>T)
c.2095G>T (p.Val699Leu)
n.2199G>T
c.1978G>T (p.Val660Leu)
c.1915G>T (p.Val639Leu)
c.2014G>T (p.Val672Leu)
n.2436G>T
c.1903G>T (p.Val635Leu)
n.2416G>T
n.2242G>T
c.1705G>T (p.Val569Leu)
c.1921G>T (p.Val641Leu)
c.1939G>T (p.Val647Leu)
 dbSNP gnomAD v2 gnomAD v3 gnomAD v4
17g.42322384C=CA2260430720STAT3c.1999G= (p.Val667=)
c.*391G= (n.*391G=)
c.1972G= (p.Val658=)
n.1452G=
c.*387G= (n.*387G=)
c.2095G= (p.Val699=)
n.2199G=
c.1978G= (p.Val660=)
c.1915G= (p.Val639=)
c.2014G= (p.Val672=)
n.2436G=
c.1903G= (p.Val635=)
n.2416G=
n.2242G=
c.1705G= (p.Val569=)
c.1921G= (p.Val641=)
c.1939G= (p.Val647=)
17g.42322384C>GCA399581764STAT3c.1999G>C (p.Val667Leu)
c.*391G>C (n.*391G>C)
c.1972G>C (p.Val658Leu)
n.1452G>C
c.*387G>C (n.*387G>C)
c.2095G>C (p.Val699Leu)
n.2199G>C
c.1978G>C (p.Val660Leu)
c.1915G>C (p.Val639Leu)
c.2014G>C (p.Val672Leu)
n.2436G>C
c.1903G>C (p.Val635Leu)
n.2416G>C
n.2242G>C
c.1705G>C (p.Val569Leu)
c.1921G>C (p.Val641Leu)
c.1939G>C (p.Val647Leu)
 dbSNP
17g.42322384C>TCA399581768STAT3c.1999G>A (p.Val667Met)
c.*391G>A (n.*391G>A)
c.1972G>A (p.Val658Met)
n.1452G>A
c.*387G>A (n.*387G>A)
c.2095G>A (p.Val699Met)
n.2199G>A
c.1978G>A (p.Val660Met)
c.1915G>A (p.Val639Met)
c.2014G>A (p.Val672Met)
n.2436G>A
c.1903G>A (p.Val635Met)
n.2416G>A
n.2242G>A
c.1705G>A (p.Val569Met)
c.1921G>A (p.Val641Met)
c.1939G>A (p.Val647Met)
 dbSNP
17g.42322385delCA2733835225STAT3c.1999del (p.Val667CysfsTer?)
c.*391del (n.*391del)
c.1972del (p.Val658CysfsTer?)
n.1452del
c.*387del (n.*387del)
c.2095del (p.Val699CysfsTer?)
n.2199del
c.1978del (p.Val660CysfsTer?)
c.1915del (p.Val639CysfsTer?)
c.2014del (p.Val672CysfsTer?)
n.2436del
c.1903del (p.Val635CysfsTer?)
n.2416del
n.2242del
c.1705del (p.Val569CysfsTer?)
c.1921del (p.Val641CysfsTer?)
c.1939del (p.Val647CysfsTer?)
 dbSNP
17g.42322385C>ACA500061068STAT3c.1998G>T (p.Leu666=)
c.*390G>T (n.*390G>T)
c.1971G>T (p.Leu657=)
n.1451G>T
c.*386G>T (n.*386G>T)
c.2094G>T (p.Leu698=)
n.2198G>T
c.1977G>T (p.Leu659=)
c.1914G>T (p.Leu638=)
c.2013G>T (p.Leu671=)
n.2435G>T
c.1902G>T (p.Leu634=)
n.2415G>T
n.2241G>T
c.1704G>T (p.Leu568=)
c.1920G>T (p.Leu640=)
c.1938G>T (p.Leu646=)
17g.42322385C=CA2260430721STAT3c.1998G= (p.Leu666=)
c.*390G= (n.*390G=)
c.1971G= (p.Leu657=)
n.1451G=
c.*386G= (n.*386G=)
c.2094G= (p.Leu698=)
n.2198G=
c.1977G= (p.Leu659=)
c.1914G= (p.Leu638=)
c.2013G= (p.Leu671=)
n.2435G=
c.1902G= (p.Leu634=)
n.2415G=
n.2241G=
c.1704G= (p.Leu568=)
c.1920G= (p.Leu640=)
c.1938G= (p.Leu646=)
17g.42322385C>GCA500061067STAT3c.1998G>C (p.Leu666=)
c.*390G>C (n.*390G>C)
c.1971G>C (p.Leu657=)
n.1451G>C
c.*386G>C (n.*386G>C)
c.2094G>C (p.Leu698=)
n.2198G>C
c.1977G>C (p.Leu659=)
c.1914G>C (p.Leu638=)
c.2013G>C (p.Leu671=)
n.2435G>C
c.1902G>C (p.Leu634=)
n.2415G>C
n.2241G>C
c.1704G>C (p.Leu568=)
c.1920G>C (p.Leu640=)
c.1938G>C (p.Leu646=)
 dbSNP gnomAD v2 gnomAD v4
17g.42322385C>TCA500061069STAT3c.1998G>A (p.Leu666=)
c.*390G>A (n.*390G>A)
c.1971G>A (p.Leu657=)
n.1451G>A
c.*386G>A (n.*386G>A)
c.2094G>A (p.Leu698=)
n.2198G>A
c.1977G>A (p.Leu659=)
c.1914G>A (p.Leu638=)
c.2013G>A (p.Leu671=)
n.2435G>A
c.1902G>A (p.Leu634=)
n.2415G>A
n.2241G>A
c.1704G>A (p.Leu568=)
c.1920G>A (p.Leu640=)
c.1938G>A (p.Leu646=)
 dbSNP gnomAD v3 gnomAD v4
17g.42322386A>CCA399581770STAT3c.1997T>G (p.Leu666Arg)
c.*389T>G (n.*389T>G)
c.1970T>G (p.Leu657Arg)
n.1450T>G
c.*385T>G (n.*385T>G)
c.2093T>G (p.Leu698Arg)
n.2197T>G
c.1976T>G (p.Leu659Arg)
c.1913T>G (p.Leu638Arg)
c.2012T>G (p.Leu671Arg)
n.2434T>G
c.1901T>G (p.Leu634Arg)
n.2414T>G
n.2240T>G
c.1703T>G (p.Leu568Arg)
c.1919T>G (p.Leu640Arg)
c.1937T>G (p.Leu646Arg)
17g.42322386A>GCA399581774STAT3c.1997T>C (p.Leu666Pro)
c.*389T>C (n.*389T>C)
c.1970T>C (p.Leu657Pro)
n.1450T>C
c.*385T>C (n.*385T>C)
c.2093T>C (p.Leu698Pro)
n.2197T>C
c.1976T>C (p.Leu659Pro)
c.1913T>C (p.Leu638Pro)
c.2012T>C (p.Leu671Pro)
n.2434T>C
c.1901T>C (p.Leu634Pro)
n.2414T>C
n.2240T>C
c.1703T>C (p.Leu568Pro)
c.1919T>C (p.Leu640Pro)
c.1937T>C (p.Leu646Pro)
 dbSNP
17g.42322386A>TCA399581771STAT3c.1997T>A (p.Leu666Gln)
c.*389T>A (n.*389T>A)
c.1970T>A (p.Leu657Gln)
n.1450T>A
c.*385T>A (n.*385T>A)
c.2093T>A (p.Leu698Gln)
n.2197T>A
c.1976T>A (p.Leu659Gln)
c.1913T>A (p.Leu638Gln)
c.2012T>A (p.Leu671Gln)
n.2434T>A
c.1901T>A (p.Leu634Gln)
n.2414T>A
n.2240T>A
c.1703T>A (p.Leu568Gln)
c.1919T>A (p.Leu640Gln)
c.1937T>A (p.Leu646Gln)
 dbSNP
17g.42322387G>ACA500061070STAT3c.1996C>T (p.Leu666=)
c.*388C>T (n.*388C>T)
c.1969C>T (p.Leu657=)
n.1449C>T
c.*384C>T (n.*384C>T)
c.2092C>T (p.Leu698=)
n.2196C>T
c.1975C>T (p.Leu659=)
c.1912C>T (p.Leu638=)
c.2011C>T (p.Leu671=)
n.2433C>T
c.1900C>T (p.Leu634=)
n.2413C>T
n.2239C>T
c.1702C>T (p.Leu568=)
c.1918C>T (p.Leu640=)
c.1936C>T (p.Leu646=)
 dbSNP
17g.42322387G>CCA399581776STAT3c.1996C>G (p.Leu666Val)
c.*388C>G (n.*388C>G)
c.1969C>G (p.Leu657Val)
n.1449C>G
c.*384C>G (n.*384C>G)
c.2092C>G (p.Leu698Val)
n.2196C>G
c.1975C>G (p.Leu659Val)
c.1912C>G (p.Leu638Val)
c.2011C>G (p.Leu671Val)
n.2433C>G
c.1900C>G (p.Leu634Val)
n.2413C>G
n.2239C>G
c.1702C>G (p.Leu568Val)
c.1918C>G (p.Leu640Val)
c.1936C>G (p.Leu646Val)
 dbSNP
17g.42322387G>TCA399581777STAT3c.1996C>A (p.Leu666Met)
c.*388C>A (n.*388C>A)
c.1969C>A (p.Leu657Met)
n.1449C>A
c.*384C>A (n.*384C>A)
c.2092C>A (p.Leu698Met)
n.2196C>A
c.1975C>A (p.Leu659Met)
c.1912C>A (p.Leu638Met)
c.2011C>A (p.Leu671Met)
n.2433C>A
c.1900C>A (p.Leu634Met)
n.2413C>A
n.2239C>A
c.1702C>A (p.Leu568Met)
c.1918C>A (p.Leu640Met)
c.1936C>A (p.Leu646Met)
 dbSNP COSMIC
17g.42322388G>ACA500061072STAT3c.1995C>T (p.Ile665=)
c.*387C>T (n.*387C>T)
c.1968C>T (p.Ile656=)
n.1448C>T
c.*383C>T (n.*383C>T)
c.2091C>T (p.Ile697=)
n.2195C>T
c.1974C>T (p.Ile658=)
c.1911C>T (p.Ile637=)
c.2010C>T (p.Ile670=)
n.2432C>T
c.1899C>T (p.Ile633=)
n.2412C>T
n.2238C>T
c.1701C>T (p.Ile567=)
c.1917C>T (p.Ile639=)
c.1935C>T (p.Ile645=)
 dbSNP gnomAD v3 gnomAD v4 COSMIC
17g.42322388G>CCA399581779STAT3c.1995C>G (p.Ile665Met)
c.*387C>G (n.*387C>G)
c.1968C>G (p.Ile656Met)
n.1448C>G
c.*383C>G (n.*383C>G)
c.2091C>G (p.Ile697Met)
n.2195C>G
c.1974C>G (p.Ile658Met)
c.1911C>G (p.Ile637Met)
c.2010C>G (p.Ile670Met)
n.2432C>G
c.1899C>G (p.Ile633Met)
n.2412C>G
n.2238C>G
c.1701C>G (p.Ile567Met)
c.1917C>G (p.Ile639Met)
c.1935C>G (p.Ile645Met)
 dbSNP
17g.42322388G=CA2260430722STAT3c.1995C= (p.Ile665=)
c.*387C= (n.*387C=)
c.1968C= (p.Ile656=)
n.1448C=
c.*383C= (n.*383C=)
c.2091C= (p.Ile697=)
n.2195C=
c.1974C= (p.Ile658=)
c.1911C= (p.Ile637=)
c.2010C= (p.Ile670=)
n.2432C=
c.1899C= (p.Ile633=)
n.2412C=
n.2238C=
c.1701C= (p.Ile567=)
c.1917C= (p.Ile639=)
c.1935C= (p.Ile645=)
17g.42322388G>TCA500061071STAT3c.1995C>A (p.Ile665=)
c.*387C>A (n.*387C>A)
c.1968C>A (p.Ile656=)
n.1448C>A
c.*383C>A (n.*383C>A)
c.2091C>A (p.Ile697=)
n.2195C>A
c.1974C>A (p.Ile658=)
c.1911C>A (p.Ile637=)
c.2010C>A (p.Ile670=)
n.2432C>A
c.1899C>A (p.Ile633=)
n.2412C>A
n.2238C>A
c.1701C>A (p.Ile567=)
c.1917C>A (p.Ile639=)
c.1935C>A (p.Ile645=)
 dbSNP
17g.42322389A>CCA399581784STAT3c.1994T>G (p.Ile665Ser)
c.*386T>G (n.*386T>G)
c.1967T>G (p.Ile656Ser)
n.1447T>G
c.*382T>G (n.*382T>G)
c.2090T>G (p.Ile697Ser)
n.2194T>G
c.1973T>G (p.Ile658Ser)
c.1910T>G (p.Ile637Ser)
c.2009T>G (p.Ile670Ser)
n.2431T>G
c.1898T>G (p.Ile633Ser)
n.2411T>G
n.2237T>G
c.1700T>G (p.Ile567Ser)
c.1916T>G (p.Ile639Ser)
c.1934T>G (p.Ile645Ser)
17g.42322389A>GCA399581786STAT3c.1994T>C (p.Ile665Thr)
c.*386T>C (n.*386T>C)
c.1967T>C (p.Ile656Thr)
n.1447T>C
c.*382T>C (n.*382T>C)
c.2090T>C (p.Ile697Thr)
n.2194T>C
c.1973T>C (p.Ile658Thr)
c.1910T>C (p.Ile637Thr)
c.2009T>C (p.Ile670Thr)
n.2431T>C
c.1898T>C (p.Ile633Thr)
n.2411T>C
n.2237T>C
c.1700T>C (p.Ile567Thr)
c.1916T>C (p.Ile639Thr)
c.1934T>C (p.Ile645Thr)
 dbSNP
17g.42322389A>TCA399581787STAT3c.1994T>A (p.Ile665Asn)
c.*386T>A (n.*386T>A)
c.1967T>A (p.Ile656Asn)
n.1447T>A
c.*382T>A (n.*382T>A)
c.2090T>A (p.Ile697Asn)
n.2194T>A
c.1973T>A (p.Ile658Asn)
c.1910T>A (p.Ile637Asn)
c.2009T>A (p.Ile670Asn)
n.2431T>A
c.1898T>A (p.Ile633Asn)
n.2411T>A
n.2237T>A
c.1700T>A (p.Ile567Asn)
c.1916T>A (p.Ile639Asn)
c.1934T>A (p.Ile645Asn)
17g.42322390T>ACA399581788STAT3c.1993A>T (p.Ile665Phe)
c.*385A>T (n.*385A>T)
c.1966A>T (p.Ile656Phe)
n.1446A>T
c.*381A>T (n.*381A>T)
c.2089A>T (p.Ile697Phe)
n.2193A>T
c.1972A>T (p.Ile658Phe)
c.1909A>T (p.Ile637Phe)
c.2008A>T (p.Ile670Phe)
n.2430A>T
c.1897A>T (p.Ile633Phe)
n.2410A>T
n.2236A>T
c.1699A>T (p.Ile567Phe)
c.1915A>T (p.Ile639Phe)
c.1933A>T (p.Ile645Phe)
 ClinVar dbSNP
17g.42322390T>CCA399581789STAT3c.1993A>G (p.Ile665Val)
c.*385A>G (n.*385A>G)
c.1966A>G (p.Ile656Val)
n.1446A>G
c.*381A>G (n.*381A>G)
c.2089A>G (p.Ile697Val)
n.2193A>G
c.1972A>G (p.Ile658Val)
c.1909A>G (p.Ile637Val)
c.2008A>G (p.Ile670Val)
n.2430A>G
c.1897A>G (p.Ile633Val)
n.2410A>G
n.2236A>G
c.1699A>G (p.Ile567Val)
c.1915A>G (p.Ile639Val)
c.1933A>G (p.Ile645Val)
17g.42322390T>GCA399581791STAT3c.1993A>C (p.Ile665Leu)
c.*385A>C (n.*385A>C)
c.1966A>C (p.Ile656Leu)
n.1446A>C
c.*381A>C (n.*381A>C)
c.2089A>C (p.Ile697Leu)
n.2193A>C
c.1972A>C (p.Ile658Leu)
c.1909A>C (p.Ile637Leu)
c.2008A>C (p.Ile670Leu)
n.2430A>C
c.1897A>C (p.Ile633Leu)
n.2410A>C
n.2236A>C
c.1699A>C (p.Ile567Leu)
c.1915A>C (p.Ile639Leu)
c.1933A>C (p.Ile645Leu)
 dbSNP
17g.42322390T=CA2260430723STAT3c.1993A= (p.Ile665=)
c.*385A= (n.*385A=)
c.1966A= (p.Ile656=)
n.1446A=
c.*381A= (n.*381A=)
c.2089A= (p.Ile697=)
n.2193A=
c.1972A= (p.Ile658=)
c.1909A= (p.Ile637=)
c.2008A= (p.Ile670=)
n.2430A=
c.1897A= (p.Ile633=)
n.2410A=
n.2236A=
c.1699A= (p.Ile567=)
c.1915A= (p.Ile639=)
c.1933A= (p.Ile645=)
17g.42322391A>CCA399581792STAT3c.1992T>G (p.Asn664Lys)
c.*384T>G (n.*384T>G)
c.1965T>G (p.Asn655Lys)
n.1445T>G
c.*380T>G (n.*380T>G)
c.2088T>G (p.Asn696Lys)
n.2192T>G
c.1971T>G (p.Asn657Lys)
c.1908T>G (p.Asn636Lys)
c.2007T>G (p.Asn669Lys)
n.2429T>G
c.1896T>G (p.Asn632Lys)
n.2409T>G
n.2235T>G
c.1698T>G (p.Asn566Lys)
c.1914T>G (p.Asn638Lys)
c.1932T>G (p.Asn644Lys)
17g.42322391A>GCA500061074STAT3c.1992T>C (p.Asn664=)
c.*384T>C (n.*384T>C)
c.1965T>C (p.Asn655=)
n.1445T>C
c.*380T>C (n.*380T>C)
c.2088T>C (p.Asn696=)
n.2192T>C
c.1971T>C (p.Asn657=)
c.1908T>C (p.Asn636=)
c.2007T>C (p.Asn669=)
n.2429T>C
c.1896T>C (p.Asn632=)
n.2409T>C
n.2235T>C
c.1698T>C (p.Asn566=)
c.1914T>C (p.Asn638=)
c.1932T>C (p.Asn644=)
 gnomAD v4 COSMIC
17g.42322391A>TCA399581793STAT3c.1992T>A (p.Asn664Lys)
c.*384T>A (n.*384T>A)
c.1965T>A (p.Asn655Lys)
n.1445T>A
c.*380T>A (n.*380T>A)
c.2088T>A (p.Asn696Lys)
n.2192T>A
c.1971T>A (p.Asn657Lys)
c.1908T>A (p.Asn636Lys)
c.2007T>A (p.Asn669Lys)
n.2429T>A
c.1896T>A (p.Asn632Lys)
n.2409T>A
n.2235T>A
c.1698T>A (p.Asn566Lys)
c.1914T>A (p.Asn638Lys)
c.1932T>A (p.Asn644Lys)
 dbSNP
17g.42322392T>ACA399581794STAT3c.1991A>T (p.Asn664Ile)
c.*383A>T (n.*383A>T)
c.1964A>T (p.Asn655Ile)
n.1444A>T
c.*379A>T (n.*379A>T)
c.2087A>T (p.Asn696Ile)
n.2191A>T
c.1970A>T (p.Asn657Ile)
c.1907A>T (p.Asn636Ile)
c.2006A>T (p.Asn669Ile)
n.2428A>T
c.1895A>T (p.Asn632Ile)
n.2408A>T
n.2234A>T
c.1697A>T (p.Asn566Ile)
c.1913A>T (p.Asn638Ile)
c.1931A>T (p.Asn644Ile)
 dbSNP
17g.42322392T>CCA399581795STAT3c.1991A>G (p.Asn664Ser)
c.*383A>G (n.*383A>G)
c.1964A>G (p.Asn655Ser)
n.1444A>G
c.*379A>G (n.*379A>G)
c.2087A>G (p.Asn696Ser)
n.2191A>G
c.1970A>G (p.Asn657Ser)
c.1907A>G (p.Asn636Ser)
c.2006A>G (p.Asn669Ser)
n.2428A>G
c.1895A>G (p.Asn632Ser)
n.2408A>G
n.2234A>G
c.1697A>G (p.Asn566Ser)
c.1913A>G (p.Asn638Ser)
c.1931A>G (p.Asn644Ser)
17g.42322392T>GCA399581796STAT3c.1991A>C (p.Asn664Thr)
c.*383A>C (n.*383A>C)
c.1964A>C (p.Asn655Thr)
n.1444A>C
c.*379A>C (n.*379A>C)
c.2087A>C (p.Asn696Thr)
n.2191A>C
c.1970A>C (p.Asn657Thr)
c.1907A>C (p.Asn636Thr)
c.2006A>C (p.Asn669Thr)
n.2428A>C
c.1895A>C (p.Asn632Thr)
n.2408A>C
n.2234A>C
c.1697A>C (p.Asn566Thr)
c.1913A>C (p.Asn638Thr)
c.1931A>C (p.Asn644Thr)
17g.42322393T>ACA399581803STAT3c.1990A>T (p.Asn664Tyr)
c.*382A>T (n.*382A>T)
c.1963A>T (p.Asn655Tyr)
n.1443A>T
c.*378A>T (n.*378A>T)
c.2086A>T (p.Asn696Tyr)
n.2190A>T
c.1969A>T (p.Asn657Tyr)
c.1906A>T (p.Asn636Tyr)
c.2005A>T (p.Asn669Tyr)
n.2427A>T
c.1894A>T (p.Asn632Tyr)
n.2407A>T
n.2233A>T
c.1696A>T (p.Asn566Tyr)
c.1912A>T (p.Asn638Tyr)
c.1930A>T (p.Asn644Tyr)
17g.42322393T>CCA399581798STAT3c.1990A>G (p.Asn664Asp)
c.*382A>G (n.*382A>G)
c.1963A>G (p.Asn655Asp)
n.1443A>G
c.*378A>G (n.*378A>G)
c.2086A>G (p.Asn696Asp)
n.2190A>G
c.1969A>G (p.Asn657Asp)
c.1906A>G (p.Asn636Asp)
c.2005A>G (p.Asn669Asp)
n.2427A>G
c.1894A>G (p.Asn632Asp)
n.2407A>G
n.2233A>G
c.1696A>G (p.Asn566Asp)
c.1912A>G (p.Asn638Asp)
c.1930A>G (p.Asn644Asp)
17g.42322393T>GCA399581801STAT3c.1990A>C (p.Asn664His)
c.*382A>C (n.*382A>C)
c.1963A>C (p.Asn655His)
n.1443A>C
c.*378A>C (n.*378A>C)
c.2086A>C (p.Asn696His)
n.2190A>C
c.1969A>C (p.Asn657His)
c.1906A>C (p.Asn636His)
c.2005A>C (p.Asn669His)
n.2427A>C
c.1894A>C (p.Asn632His)
n.2407A>C
n.2233A>C
c.1696A>C (p.Asn566His)
c.1912A>C (p.Asn638His)
c.1930A>C (p.Asn644His)
17g.42322394G>ACA500061075STAT3c.1989C>T (p.Thr663=)
c.*381C>T (n.*381C>T)
c.1962C>T (p.Thr654=)
n.1442C>T
c.*377C>T (n.*377C>T)
c.2085C>T (p.Thr695=)
n.2189C>T
c.1968C>T (p.Thr656=)
c.1905C>T (p.Thr635=)
c.2004C>T (p.Thr668=)
n.2426C>T
c.1893C>T (p.Thr631=)
n.2406C>T
n.2232C>T
c.1695C>T (p.Thr565=)
c.1911C>T (p.Thr637=)
c.1929C>T (p.Thr643=)
 dbSNP gnomAD v3 gnomAD v4
17g.42322394G>CCA500061077STAT3c.1989C>G (p.Thr663=)
c.*381C>G (n.*381C>G)
c.1962C>G (p.Thr654=)
n.1442C>G
c.*377C>G (n.*377C>G)
c.2085C>G (p.Thr695=)
n.2189C>G
c.1968C>G (p.Thr656=)
c.1905C>G (p.Thr635=)
c.2004C>G (p.Thr668=)
n.2426C>G
c.1893C>G (p.Thr631=)
n.2406C>G
n.2232C>G
c.1695C>G (p.Thr565=)
c.1911C>G (p.Thr637=)
c.1929C>G (p.Thr643=)
 dbSNP
17g.42322394G=CA2260430724STAT3c.1989C= (p.Thr663=)
c.*381C= (n.*381C=)
c.1962C= (p.Thr654=)
n.1442C=
c.*377C= (n.*377C=)
c.2085C= (p.Thr695=)
n.2189C=
c.1968C= (p.Thr656=)
c.1905C= (p.Thr635=)
c.2004C= (p.Thr668=)
n.2426C=
c.1893C= (p.Thr631=)
n.2406C=
n.2232C=
c.1695C= (p.Thr565=)
c.1911C= (p.Thr637=)
c.1929C= (p.Thr643=)
17g.42322394G>TCA500061076STAT3c.1989C>A (p.Thr663=)
c.*381C>A (n.*381C>A)
c.1962C>A (p.Thr654=)
n.1442C>A
c.*377C>A (n.*377C>A)
c.2085C>A (p.Thr695=)
n.2189C>A
c.1968C>A (p.Thr656=)
c.1905C>A (p.Thr635=)
c.2004C>A (p.Thr668=)
n.2426C>A
c.1893C>A (p.Thr631=)
n.2406C>A
n.2232C>A
c.1695C>A (p.Thr565=)
c.1911C>A (p.Thr637=)
c.1929C>A (p.Thr643=)
 dbSNP gnomAD v4
17g.42322394_42322395delinsAACA645589633STAT3c.1988_1989delinsTT (p.Thr663Ile)
c.*380_*381delinsTT (n.*380_*381delinsTT)
c.1961_1962delinsTT (p.Thr654Ile)
n.1441_1442delinsTT
c.*376_*377delinsTT (n.*376_*377delinsTT)
c.2084_2085delinsTT (p.Thr695Ile)
n.2188_2189delinsTT
c.1967_1968delinsTT (p.Thr656Ile)
c.1904_1905delinsTT (p.Thr635Ile)
c.2003_2004delinsTT (p.Thr668Ile)
n.2425_2426delinsTT
c.1892_1893delinsTT (p.Thr631Ile)
n.2405_2406delinsTT
n.2231_2232delinsTT
c.1694_1695delinsTT (p.Thr565Ile)
c.1910_1911delinsTT (p.Thr637Ile)
c.1928_1929delinsTT (p.Thr643Ile)
 COSMIC
17g.42322395delCA2733835544STAT3c.1989del (p.Asn664IlefsTer?)
c.*381del (n.*381del)
c.1962del (p.Asn655IlefsTer?)
n.1442del
c.*377del (n.*377del)
c.2085del (p.Asn696IlefsTer?)
n.2189del
c.1968del (p.Asn657IlefsTer?)
c.1905del (p.Asn636IlefsTer?)
c.2004del (p.Asn669IlefsTer?)
n.2426del
c.1893del (p.Asn632IlefsTer?)
n.2406del
n.2232del
c.1695del (p.Asn566IlefsTer?)
c.1911del (p.Asn638IlefsTer?)
c.1929del (p.Asn644IlefsTer?)
 dbSNP
17g.42322395G>ACA357959STAT3c.1988C>T (p.Thr663Ile)
c.*380C>T (n.*380C>T)
c.1961C>T (p.Thr654Ile)
n.1441C>T
c.*376C>T (n.*376C>T)
c.2084C>T (p.Thr695Ile)
n.2188C>T
c.1967C>T (p.Thr656Ile)
c.1904C>T (p.Thr635Ile)
c.2003C>T (p.Thr668Ile)
n.2425C>T
c.1892C>T (p.Thr631Ile)
n.2405C>T
n.2231C>T
c.1694C>T (p.Thr565Ile)
c.1910C>T (p.Thr637Ile)
c.1928C>T (p.Thr643Ile)
 ClinVar dbSNP
17g.42322395G>CCA399581808STAT3c.1988C>G (p.Thr663Ser)
c.*380C>G (n.*380C>G)
c.1961C>G (p.Thr654Ser)
n.1441C>G
c.*376C>G (n.*376C>G)
c.2084C>G (p.Thr695Ser)
n.2188C>G
c.1967C>G (p.Thr656Ser)
c.1904C>G (p.Thr635Ser)
c.2003C>G (p.Thr668Ser)
n.2425C>G
c.1892C>G (p.Thr631Ser)
n.2405C>G
n.2231C>G
c.1694C>G (p.Thr565Ser)
c.1910C>G (p.Thr637Ser)
c.1928C>G (p.Thr643Ser)
 dbSNP
17g.42322395G=CA2260430725STAT3c.1988C= (p.Thr663=)
c.*380C= (n.*380C=)
c.1961C= (p.Thr654=)
n.1441C=
c.*376C= (n.*376C=)
c.2084C= (p.Thr695=)
n.2188C=
c.1967C= (p.Thr656=)
c.1904C= (p.Thr635=)
c.2003C= (p.Thr668=)
n.2425C=
c.1892C= (p.Thr631=)
n.2405C=
n.2231C=
c.1694C= (p.Thr565=)
c.1910C= (p.Thr637=)
c.1928C= (p.Thr643=)
17g.42322395G>TCA399581811STAT3c.1988C>A (p.Thr663Asn)
c.*380C>A (n.*380C>A)
c.1961C>A (p.Thr654Asn)
n.1441C>A
c.*376C>A (n.*376C>A)
c.2084C>A (p.Thr695Asn)
n.2188C>A
c.1967C>A (p.Thr656Asn)
c.1904C>A (p.Thr635Asn)
c.2003C>A (p.Thr668Asn)
n.2425C>A
c.1892C>A (p.Thr631Asn)
n.2405C>A
n.2231C>A
c.1694C>A (p.Thr565Asn)
c.1910C>A (p.Thr637Asn)
c.1928C>A (p.Thr643Asn)
 dbSNP
17g.42322395_42322396delinsAGCA2740095340STAT3c.1987_1988delinsCT (p.Thr663Leu)
c.*379_*380delinsCT (n.*379_*380delinsCT)
c.1960_1961delinsCT (p.Thr654Leu)
n.1440_1441delinsCT
c.*375_*376delinsCT (n.*375_*376delinsCT)
c.2083_2084delinsCT (p.Thr695Leu)
n.2187_2188delinsCT
c.1966_1967delinsCT (p.Thr656Leu)
c.1903_1904delinsCT (p.Thr635Leu)
c.2002_2003delinsCT (p.Thr668Leu)
n.2424_2425delinsCT
c.1891_1892delinsCT (p.Thr631Leu)
n.2404_2405delinsCT
n.2230_2231delinsCT
c.1693_1694delinsCT (p.Thr565Leu)
c.1909_1910delinsCT (p.Thr637Leu)
c.1927_1928delinsCT (p.Thr643Leu)
 ClinVar
17g.42322396T>ACA399581817STAT3c.1987A>T (p.Thr663Ser)
c.*379A>T (n.*379A>T)
c.1960A>T (p.Thr654Ser)
n.1440A>T
c.*375A>T (n.*375A>T)
c.2083A>T (p.Thr695Ser)
n.2187A>T
c.1966A>T (p.Thr656Ser)
c.1903A>T (p.Thr635Ser)
c.2002A>T (p.Thr668Ser)
n.2424A>T
c.1891A>T (p.Thr631Ser)
n.2404A>T
n.2230A>T
c.1693A>T (p.Thr565Ser)
c.1909A>T (p.Thr637Ser)
c.1927A>T (p.Thr643Ser)
 dbSNP
17g.42322396T>CCA399581820STAT3c.1987A>G (p.Thr663Ala)
c.*379A>G (n.*379A>G)
c.1960A>G (p.Thr654Ala)
n.1440A>G
c.*375A>G (n.*375A>G)
c.2083A>G (p.Thr695Ala)
n.2187A>G
c.1966A>G (p.Thr656Ala)
c.1903A>G (p.Thr635Ala)
c.2002A>G (p.Thr668Ala)
n.2424A>G
c.1891A>G (p.Thr631Ala)
n.2404A>G
n.2230A>G
c.1693A>G (p.Thr565Ala)
c.1909A>G (p.Thr637Ala)
c.1927A>G (p.Thr643Ala)
17g.42322396T>GCA399581822STAT3c.1987A>C (p.Thr663Pro)
c.*379A>C (n.*379A>C)
c.1960A>C (p.Thr654Pro)
n.1440A>C
c.*375A>C (n.*375A>C)
c.2083A>C (p.Thr695Pro)
n.2187A>C
c.1966A>C (p.Thr656Pro)
c.1903A>C (p.Thr635Pro)
c.2002A>C (p.Thr668Pro)
n.2424A>C
c.1891A>C (p.Thr631Pro)
n.2404A>C
n.2230A>C
c.1693A>C (p.Thr565Pro)
c.1909A>C (p.Thr637Pro)
c.1927A>C (p.Thr643Pro)
 dbSNP
17g.42322397A>CCA500061080STAT3c.1986T>G (p.Ala662=)
c.*378T>G (n.*378T>G)
c.1959T>G (p.Ala653=)
n.1439T>G
c.*374T>G (n.*374T>G)
c.2082T>G (p.Ala694=)
n.2186T>G
c.1965T>G (p.Ala655=)
c.1902T>G (p.Ala634=)
c.2001T>G (p.Ala667=)
n.2423T>G
c.1890T>G (p.Ala630=)
n.2403T>G
n.2229T>G
c.1692T>G (p.Ala564=)
c.1908T>G (p.Ala636=)
c.1926T>G (p.Ala642=)
 COSMIC
17g.42322397A>GCA500061078STAT3c.1986T>C (p.Ala662=)
c.*378T>C (n.*378T>C)
c.1959T>C (p.Ala653=)
n.1439T>C
c.*374T>C (n.*374T>C)
c.2082T>C (p.Ala694=)
n.2186T>C
c.1965T>C (p.Ala655=)
c.1902T>C (p.Ala634=)
c.2001T>C (p.Ala667=)
n.2423T>C
c.1890T>C (p.Ala630=)
n.2403T>C
n.2229T>C
c.1692T>C (p.Ala564=)
c.1908T>C (p.Ala636=)
c.1926T>C (p.Ala642=)
 dbSNP
17g.42322397A>TCA500061079STAT3c.1986T>A (p.Ala662=)
c.*378T>A (n.*378T>A)
c.1959T>A (p.Ala653=)
n.1439T>A
c.*374T>A (n.*374T>A)
c.2082T>A (p.Ala694=)
n.2186T>A
c.1965T>A (p.Ala655=)
c.1902T>A (p.Ala634=)
c.2001T>A (p.Ala667=)
n.2423T>A
c.1890T>A (p.Ala630=)
n.2403T>A
n.2229T>A
c.1692T>A (p.Ala564=)
c.1908T>A (p.Ala636=)
c.1926T>A (p.Ala642=)
 dbSNP
17g.42322398G>ACA399581827STAT3c.1985C>T (p.Ala662Val)
c.*377C>T (n.*377C>T)
c.1958C>T (p.Ala653Val)
n.1438C>T
c.*373C>T (n.*373C>T)
c.2081C>T (p.Ala694Val)
n.2185C>T
c.1964C>T (p.Ala655Val)
c.1901C>T (p.Ala634Val)
c.2000C>T (p.Ala667Val)
n.2422C>T
c.1889C>T (p.Ala630Val)
n.2402C>T
n.2228C>T
c.1691C>T (p.Ala564Val)
c.1907C>T (p.Ala636Val)
c.1925C>T (p.Ala642Val)
 dbSNP
17g.42322398G>CCA399581829STAT3c.1985C>G (p.Ala662Gly)
c.*377C>G (n.*377C>G)
c.1958C>G (p.Ala653Gly)
n.1438C>G
c.*373C>G (n.*373C>G)
c.2081C>G (p.Ala694Gly)
n.2185C>G
c.1964C>G (p.Ala655Gly)
c.1901C>G (p.Ala634Gly)
c.2000C>G (p.Ala667Gly)
n.2422C>G
c.1889C>G (p.Ala630Gly)
n.2402C>G
n.2228C>G
c.1691C>G (p.Ala564Gly)
c.1907C>G (p.Ala636Gly)
c.1925C>G (p.Ala642Gly)
 dbSNP
17g.42322398G>TCA399581832STAT3c.1985C>A (p.Ala662Asp)
c.*377C>A (n.*377C>A)
c.1958C>A (p.Ala653Asp)
n.1438C>A
c.*373C>A (n.*373C>A)
c.2081C>A (p.Ala694Asp)
n.2185C>A
c.1964C>A (p.Ala655Asp)
c.1901C>A (p.Ala634Asp)
c.2000C>A (p.Ala667Asp)
n.2422C>A
c.1889C>A (p.Ala630Asp)
n.2402C>A
n.2228C>A
c.1691C>A (p.Ala564Asp)
c.1907C>A (p.Ala636Asp)
c.1925C>A (p.Ala642Asp)
17g.42322399C>ACA399581848STAT3c.1984G>T (p.Ala662Ser)
c.*376G>T (n.*376G>T)
c.1957G>T (p.Ala653Ser)
n.1437G>T
c.*372G>T (n.*372G>T)
c.2080G>T (p.Ala694Ser)
n.2184G>T
c.1963G>T (p.Ala655Ser)
c.1900G>T (p.Ala634Ser)
c.1999G>T (p.Ala667Ser)
n.2421G>T
c.1888G>T (p.Ala630Ser)
n.2401G>T
n.2227G>T
c.1690G>T (p.Ala564Ser)
c.1906G>T (p.Ala636Ser)
c.1924G>T (p.Ala642Ser)
 dbSNP
17g.42322399C>GCA399581855STAT3c.1984G>C (p.Ala662Pro)
c.*376G>C (n.*376G>C)
c.1957G>C (p.Ala653Pro)
n.1437G>C
c.*372G>C (n.*372G>C)
c.2080G>C (p.Ala694Pro)
n.2184G>C
c.1963G>C (p.Ala655Pro)
c.1900G>C (p.Ala634Pro)
c.1999G>C (p.Ala667Pro)
n.2421G>C
c.1888G>C (p.Ala630Pro)
n.2401G>C
n.2227G>C
c.1690G>C (p.Ala564Pro)
c.1906G>C (p.Ala636Pro)
c.1924G>C (p.Ala642Pro)
 dbSNP
17g.42322399C>TCA399581857STAT3c.1984G>A (p.Ala662Thr)
c.*376G>A (n.*376G>A)
c.1957G>A (p.Ala653Thr)
n.1437G>A
c.*372G>A (n.*372G>A)
c.2080G>A (p.Ala694Thr)
n.2184G>A
c.1963G>A (p.Ala655Thr)
c.1900G>A (p.Ala634Thr)
c.1999G>A (p.Ala667Thr)
n.2421G>A
c.1888G>A (p.Ala630Thr)
n.2401G>A
n.2227G>A
c.1690G>A (p.Ala564Thr)
c.1906G>A (p.Ala636Thr)
c.1924G>A (p.Ala642Thr)
 ClinVar dbSNP
17g.42322400A=CA2260430726STAT3c.1983T= (p.Asp661=)
c.*375T= (n.*375T=)
c.1956T= (p.Asp652=)
n.1436T=
c.*371T= (n.*371T=)
c.2079T= (p.Asp693=)
n.2183T=
c.1962T= (p.Asp654=)
c.1899T= (p.Asp633=)
c.1998T= (p.Asp666=)
n.2420T=
c.1887T= (p.Asp629=)
n.2400T=
n.2226T=
c.1689T= (p.Asp563=)
c.1905T= (p.Asp635=)
c.1923T= (p.Asp641=)
17g.42322400A>CCA399581860STAT3c.1983T>G (p.Asp661Glu)
c.*375T>G (n.*375T>G)
c.1956T>G (p.Asp652Glu)
n.1436T>G
c.*371T>G (n.*371T>G)
c.2079T>G (p.Asp693Glu)
n.2183T>G
c.1962T>G (p.Asp654Glu)
c.1899T>G (p.Asp633Glu)
c.1998T>G (p.Asp666Glu)
n.2420T>G
c.1887T>G (p.Asp629Glu)
n.2400T>G
n.2226T>G
c.1689T>G (p.Asp563Glu)
c.1905T>G (p.Asp635Glu)
c.1923T>G (p.Asp641Glu)
17g.42322400A>GCA290732193STAT3c.1983T>C (p.Asp661=)
c.*375T>C (n.*375T>C)
c.1956T>C (p.Asp652=)
n.1436T>C
c.*371T>C (n.*371T>C)
c.2079T>C (p.Asp693=)
n.2183T>C
c.1962T>C (p.Asp654=)
c.1899T>C (p.Asp633=)
c.1998T>C (p.Asp666=)
n.2420T>C
c.1887T>C (p.Asp629=)
n.2400T>C
n.2226T>C
c.1689T>C (p.Asp563=)
c.1905T>C (p.Asp635=)
c.1923T>C (p.Asp641=)
 dbSNP
17g.42322400A>TCA399581863STAT3c.1983T>A (p.Asp661Glu)
c.*375T>A (n.*375T>A)
c.1956T>A (p.Asp652Glu)
n.1436T>A
c.*371T>A (n.*371T>A)
c.2079T>A (p.Asp693Glu)
n.2183T>A
c.1962T>A (p.Asp654Glu)
c.1899T>A (p.Asp633Glu)
c.1998T>A (p.Asp666Glu)
n.2420T>A
c.1887T>A (p.Asp629Glu)
n.2400T>A
n.2226T>A
c.1689T>A (p.Asp563Glu)
c.1905T>A (p.Asp635Glu)
c.1923T>A (p.Asp641Glu)
 dbSNP
17g.42322401T>ACA399581866STAT3c.1982A>T (p.Asp661Val)
c.*374A>T (n.*374A>T)
c.1955A>T (p.Asp652Val)
n.1435A>T
c.*370A>T (n.*370A>T)
c.2078A>T (p.Asp693Val)
n.2182A>T
c.1961A>T (p.Asp654Val)
c.1898A>T (p.Asp633Val)
c.1997A>T (p.Asp666Val)
n.2419A>T
c.1886A>T (p.Asp629Val)
n.2399A>T
n.2225A>T
c.1688A>T (p.Asp563Val)
c.1904A>T (p.Asp635Val)
c.1922A>T (p.Asp641Val)
 ClinVar dbSNP gnomAD v4 COSMIC
17g.42322401T>CCA399581870STAT3c.1982A>G (p.Asp661Gly)
c.*374A>G (n.*374A>G)
c.1955A>G (p.Asp652Gly)
n.1435A>G
c.*370A>G (n.*370A>G)
c.2078A>G (p.Asp693Gly)
n.2182A>G
c.1961A>G (p.Asp654Gly)
c.1898A>G (p.Asp633Gly)
c.1997A>G (p.Asp666Gly)
n.2419A>G
c.1886A>G (p.Asp629Gly)
n.2399A>G
n.2225A>G
c.1688A>G (p.Asp563Gly)
c.1904A>G (p.Asp635Gly)
c.1922A>G (p.Asp641Gly)
 dbSNP
17g.42322401T>GCA399581880STAT3c.1982A>C (p.Asp661Ala)
c.*374A>C (n.*374A>C)
c.1955A>C (p.Asp652Ala)
n.1435A>C
c.*370A>C (n.*370A>C)
c.2078A>C (p.Asp693Ala)
n.2182A>C
c.1961A>C (p.Asp654Ala)
c.1898A>C (p.Asp633Ala)
c.1997A>C (p.Asp666Ala)
n.2419A>C
c.1886A>C (p.Asp629Ala)
n.2399A>C
n.2225A>C
c.1688A>C (p.Asp563Ala)
c.1904A>C (p.Asp635Ala)
c.1922A>C (p.Asp641Ala)
17g.42322401T=CA2260430727STAT3c.1982A= (p.Asp661=)
c.*374A= (n.*374A=)
c.1955A= (p.Asp652=)
n.1435A=
c.*370A= (n.*370A=)
c.2078A= (p.Asp693=)
n.2182A=
c.1961A= (p.Asp654=)
c.1898A= (p.Asp633=)
c.1997A= (p.Asp666=)
n.2419A=
c.1886A= (p.Asp629=)
n.2399A=
n.2225A=
c.1688A= (p.Asp563=)
c.1904A= (p.Asp635=)
c.1922A= (p.Asp641=)
17g.42322402C>ACA8575178STAT3c.1981G>T (p.Asp661Tyr)
c.*373G>T (n.*373G>T)
c.1954G>T (p.Asp652Tyr)
n.1434G>T
c.*369G>T (n.*369G>T)
c.2077G>T (p.Asp693Tyr)
n.2181G>T
c.1960G>T (p.Asp654Tyr)
c.1897G>T (p.Asp633Tyr)
c.1996G>T (p.Asp666Tyr)
n.2418G>T
c.1885G>T (p.Asp629Tyr)
n.2398G>T
n.2224G>T
c.1687G>T (p.Asp563Tyr)
c.1903G>T (p.Asp635Tyr)
c.1921G>T (p.Asp641Tyr)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v3 gnomAD v4
17g.42322402C=CA2260430728STAT3c.1981G= (p.Asp661=)
c.*373G= (n.*373G=)
c.1954G= (p.Asp652=)
n.1434G=
c.*369G= (n.*369G=)
c.2077G= (p.Asp693=)
n.2181G=
c.1960G= (p.Asp654=)
c.1897G= (p.Asp633=)
c.1996G= (p.Asp666=)
n.2418G=
c.1885G= (p.Asp629=)
n.2398G=
n.2224G=
c.1687G= (p.Asp563=)
c.1903G= (p.Asp635=)
c.1921G= (p.Asp641=)
17g.42322402C>GCA399581896STAT3c.1981G>C (p.Asp661His)
c.*373G>C (n.*373G>C)
c.1954G>C (p.Asp652His)
n.1434G>C
c.*369G>C (n.*369G>C)
c.2077G>C (p.Asp693His)
n.2181G>C
c.1960G>C (p.Asp654His)
c.1897G>C (p.Asp633His)
c.1996G>C (p.Asp666His)
n.2418G>C
c.1885G>C (p.Asp629His)
n.2398G>C
n.2224G>C
c.1687G>C (p.Asp563His)
c.1903G>C (p.Asp635His)
c.1921G>C (p.Asp641His)
 dbSNP COSMIC
17g.42322402C>TCA399581901STAT3c.1981G>A (p.Asp661Asn)
c.*373G>A (n.*373G>A)
c.1954G>A (p.Asp652Asn)
n.1434G>A
c.*369G>A (n.*369G>A)
c.2077G>A (p.Asp693Asn)
n.2181G>A
c.1960G>A (p.Asp654Asn)
c.1897G>A (p.Asp633Asn)
c.1996G>A (p.Asp666Asn)
n.2418G>A
c.1885G>A (p.Asp629Asn)
n.2398G>A
n.2224G>A
c.1687G>A (p.Asp563Asn)
c.1903G>A (p.Asp635Asn)
c.1921G>A (p.Asp641Asn)
 dbSNP COSMIC
17g.42322409_42322423delCA2695225852STAT3c.1967_1981del (p.Gly656_Met660del)
c.*359_*373del (n.*359_*373del)
c.1940_1954del (p.Gly647_Met651del)
n.1420_1434del
c.*355_*369del (n.*355_*369del)
c.2063_2077del (p.Gly688_Met692del)
n.2167_2181del
c.1946_1960del (p.Gly649_Met653del)
c.1883_1897del (p.Gly628_Met632del)
c.1982_1996del (p.Gly661_Met665del)
n.2404_2418del
c.1871_1885del (p.Gly624_Met628del)
n.2384_2398del
n.2210_2224del
c.1673_1687del (p.Gly558_Met562del)
c.1889_1903del (p.Gly630_Met634del)
c.1907_1921del (p.Gly636_Met640del)
17g.42322403C>ACA399581905STAT3c.1980G>T (p.Met660Ile)
c.*372G>T (n.*372G>T)
c.1953G>T (p.Met651Ile)
n.1433G>T
c.*368G>T (n.*368G>T)
c.2076G>T (p.Met692Ile)
n.2180G>T
c.1959G>T (p.Met653Ile)
c.1896G>T (p.Met632Ile)
c.1995G>T (p.Met665Ile)
n.2417G>T
c.1884G>T (p.Met628Ile)
n.2397G>T
n.2223G>T
c.1686G>T (p.Met562Ile)
c.1902G>T (p.Met634Ile)
c.1920G>T (p.Met640Ile)
 dbSNP
17g.42322403C>GCA399581911STAT3c.1980G>C (p.Met660Ile)
c.*372G>C (n.*372G>C)
c.1953G>C (p.Met651Ile)
n.1433G>C
c.*368G>C (n.*368G>C)
c.2076G>C (p.Met692Ile)
n.2180G>C
c.1959G>C (p.Met653Ile)
c.1896G>C (p.Met632Ile)
c.1995G>C (p.Met665Ile)
n.2417G>C
c.1884G>C (p.Met628Ile)
n.2397G>C
n.2223G>C
c.1686G>C (p.Met562Ile)
c.1902G>C (p.Met634Ile)
c.1920G>C (p.Met640Ile)
 dbSNP
17g.42322403C>TCA399581913STAT3c.1980G>A (p.Met660Ile)
c.*372G>A (n.*372G>A)
c.1953G>A (p.Met651Ile)
n.1433G>A
c.*368G>A (n.*368G>A)
c.2076G>A (p.Met692Ile)
n.2180G>A
c.1959G>A (p.Met653Ile)
c.1896G>A (p.Met632Ile)
c.1995G>A (p.Met665Ile)
n.2417G>A
c.1884G>A (p.Met628Ile)
n.2397G>A
n.2223G>A
c.1686G>A (p.Met562Ile)
c.1902G>A (p.Met634Ile)
c.1920G>A (p.Met640Ile)
 dbSNP
17g.42322403_42322414dupCA645589634STAT3c.1969_1980dup (p.Met660_Asp661insTyrLysIleMet)
c.*361_*372dup (n.*361_*372dup)
c.1942_1953dup (p.Met651_Asp652insTyrLysIleMet)
n.1422_1433dup
c.*357_*368dup (n.*357_*368dup)
c.2065_2076dup (p.Met692_Asp693insTyrLysIleMet)
n.2169_2180dup
c.1948_1959dup (p.Met653_Asp654insTyrLysIleMet)
c.1885_1896dup (p.Met632_Asp633insTyrLysIleMet)
c.1984_1995dup (p.Met665_Asp666insTyrLysIleMet)
n.2406_2417dup
c.1873_1884dup (p.Met628_Asp629insTyrLysIleMet)
n.2386_2397dup
n.2212_2223dup
c.1675_1686dup (p.Met562_Asp563insTyrLysIleMet)
c.1891_1902dup (p.Met634_Asp635insTyrLysIleMet)
c.1909_1920dup (p.Met640_Asp641insTyrLysIleMet)
 COSMIC
17g.42322404A=CA2260430729STAT3c.1979T= (p.Met660=)
c.*371T= (n.*371T=)
c.1952T= (p.Met651=)
n.1432T=
c.*367T= (n.*367T=)
c.2075T= (p.Met692=)
n.2179T=
c.1958T= (p.Met653=)
c.1895T= (p.Met632=)
c.1994T= (p.Met665=)
n.2416T=
c.1883T= (p.Met628=)
n.2396T=
n.2222T=
c.1685T= (p.Met562=)
c.1901T= (p.Met634=)
c.1919T= (p.Met640=)
17g.42322404A>CCA399581916STAT3c.1979T>G (p.Met660Arg)
c.*371T>G (n.*371T>G)
c.1952T>G (p.Met651Arg)
n.1432T>G
c.*367T>G (n.*367T>G)
c.2075T>G (p.Met692Arg)
n.2179T>G
c.1958T>G (p.Met653Arg)
c.1895T>G (p.Met632Arg)
c.1994T>G (p.Met665Arg)
n.2416T>G
c.1883T>G (p.Met628Arg)
n.2396T>G
n.2222T>G
c.1685T>G (p.Met562Arg)
c.1901T>G (p.Met634Arg)
c.1919T>G (p.Met640Arg)
17g.42322404A>GCA10588650STAT3c.1979T>C (p.Met660Thr)
c.*371T>C (n.*371T>C)
c.1952T>C (p.Met651Thr)
n.1432T>C
c.*367T>C (n.*367T>C)
c.2075T>C (p.Met692Thr)
n.2179T>C
c.1958T>C (p.Met653Thr)
c.1895T>C (p.Met632Thr)
c.1994T>C (p.Met665Thr)
n.2416T>C
c.1883T>C (p.Met628Thr)
n.2396T>C
n.2222T>C
c.1685T>C (p.Met562Thr)
c.1901T>C (p.Met634Thr)
c.1919T>C (p.Met640Thr)
 ClinVar dbSNP
17g.42322404A>TCA399581922STAT3c.1979T>A (p.Met660Lys)
c.*371T>A (n.*371T>A)
c.1952T>A (p.Met651Lys)
n.1432T>A
c.*367T>A (n.*367T>A)
c.2075T>A (p.Met692Lys)
n.2179T>A
c.1958T>A (p.Met653Lys)
c.1895T>A (p.Met632Lys)
c.1994T>A (p.Met665Lys)
n.2416T>A
c.1883T>A (p.Met628Lys)
n.2396T>A
n.2222T>A
c.1685T>A (p.Met562Lys)
c.1901T>A (p.Met634Lys)
c.1919T>A (p.Met640Lys)
 dbSNP
17g.42322405T>ACA399581930STAT3c.1978A>T (p.Met660Leu)
c.*370A>T (n.*370A>T)
c.1951A>T (p.Met651Leu)
n.1431A>T
c.*366A>T (n.*366A>T)
c.2074A>T (p.Met692Leu)
n.2178A>T
c.1957A>T (p.Met653Leu)
c.1894A>T (p.Met632Leu)
c.1993A>T (p.Met665Leu)
n.2415A>T
c.1882A>T (p.Met628Leu)
n.2395A>T
n.2221A>T
c.1684A>T (p.Met562Leu)
c.1900A>T (p.Met634Leu)
c.1918A>T (p.Met640Leu)
 dbSNP
17g.42322405T>CCA399581928STAT3c.1978A>G (p.Met660Val)
c.*370A>G (n.*370A>G)
c.1951A>G (p.Met651Val)
n.1431A>G
c.*366A>G (n.*366A>G)
c.2074A>G (p.Met692Val)
n.2178A>G
c.1957A>G (p.Met653Val)
c.1894A>G (p.Met632Val)
c.1993A>G (p.Met665Val)
n.2415A>G
c.1882A>G (p.Met628Val)
n.2395A>G
n.2221A>G
c.1684A>G (p.Met562Val)
c.1900A>G (p.Met634Val)
c.1918A>G (p.Met640Val)
 dbSNP
17g.42322405T>GCA399581925STAT3c.1978A>C (p.Met660Leu)
c.*370A>C (n.*370A>C)
c.1951A>C (p.Met651Leu)
n.1431A>C
c.*366A>C (n.*366A>C)
c.2074A>C (p.Met692Leu)
n.2178A>C
c.1957A>C (p.Met653Leu)
c.1894A>C (p.Met632Leu)
c.1993A>C (p.Met665Leu)
n.2415A>C
c.1882A>C (p.Met628Leu)
n.2395A>C
n.2221A>C
c.1684A>C (p.Met562Leu)
c.1900A>C (p.Met634Leu)
c.1918A>C (p.Met640Leu)
 gnomAD v4
17g.42322406G>ACA8575179STAT3c.1977C>T (p.Ile659=)
c.*369C>T (n.*369C>T)
c.1950C>T (p.Ile650=)
n.1430C>T
c.*365C>T (n.*365C>T)
c.2073C>T (p.Ile691=)
n.2177C>T
c.1956C>T (p.Ile652=)
c.1893C>T (p.Ile631=)
c.1992C>T (p.Ile664=)
n.2414C>T
c.1881C>T (p.Ile627=)
n.2394C>T
n.2220C>T
c.1683C>T (p.Ile561=)
c.1899C>T (p.Ile633=)
c.1917C>T (p.Ile639=)
 dbSNP ExAC gnomAD v2 gnomAD v4
17g.42322406G>CCA399581935STAT3c.1977C>G (p.Ile659Met)
c.*369C>G (n.*369C>G)
c.1950C>G (p.Ile650Met)
n.1430C>G
c.*365C>G (n.*365C>G)
c.2073C>G (p.Ile691Met)
n.2177C>G
c.1956C>G (p.Ile652Met)
c.1893C>G (p.Ile631Met)
c.1992C>G (p.Ile664Met)
n.2414C>G
c.1881C>G (p.Ile627Met)
n.2394C>G
n.2220C>G
c.1683C>G (p.Ile561Met)
c.1899C>G (p.Ile633Met)
c.1917C>G (p.Ile639Met)
 dbSNP
17g.42322406G=CA2260430730STAT3c.1977C= (p.Ile659=)
c.*369C= (n.*369C=)
c.1950C= (p.Ile650=)
n.1430C=
c.*365C= (n.*365C=)
c.2073C= (p.Ile691=)
n.2177C=
c.1956C= (p.Ile652=)
c.1893C= (p.Ile631=)
c.1992C= (p.Ile664=)
n.2414C=
c.1881C= (p.Ile627=)
n.2394C=
n.2220C=
c.1683C= (p.Ile561=)
c.1899C= (p.Ile633=)
c.1917C= (p.Ile639=)
17g.42322406G>TCA500061081STAT3c.1977C>A (p.Ile659=)
c.*369C>A (n.*369C>A)
c.1950C>A (p.Ile650=)
n.1430C>A
c.*365C>A (n.*365C>A)
c.2073C>A (p.Ile691=)
n.2177C>A
c.1956C>A (p.Ile652=)
c.1893C>A (p.Ile631=)
c.1992C>A (p.Ile664=)
n.2414C>A
c.1881C>A (p.Ile627=)
n.2394C>A
n.2220C>A
c.1683C>A (p.Ile561=)
c.1899C>A (p.Ile633=)
c.1917C>A (p.Ile639=)
 dbSNP
17g.42322407A=CA2260430731STAT3c.1976T= (p.Ile659=)
c.*368T= (n.*368T=)
c.1949T= (p.Ile650=)
n.1429T=
c.*364T= (n.*364T=)
c.2072T= (p.Ile691=)
n.2176T=
c.1955T= (p.Ile652=)
c.1892T= (p.Ile631=)
c.1991T= (p.Ile664=)
n.2413T=
c.1880T= (p.Ile627=)
n.2393T=
n.2219T=
c.1682T= (p.Ile561=)
c.1898T= (p.Ile633=)
c.1916T= (p.Ile639=)
17g.42322407A>CCA399581936STAT3c.1976T>G (p.Ile659Ser)
c.*368T>G (n.*368T>G)
c.1949T>G (p.Ile650Ser)
n.1429T>G
c.*364T>G (n.*364T>G)
c.2072T>G (p.Ile691Ser)
n.2176T>G
c.1955T>G (p.Ile652Ser)
c.1892T>G (p.Ile631Ser)
c.1991T>G (p.Ile664Ser)
n.2413T>G
c.1880T>G (p.Ile627Ser)
n.2393T>G
n.2219T>G
c.1682T>G (p.Ile561Ser)
c.1898T>G (p.Ile633Ser)
c.1916T>G (p.Ile639Ser)
17g.42322407A>GCA399581937STAT3c.1976T>C (p.Ile659Thr)
c.*368T>C (n.*368T>C)
c.1949T>C (p.Ile650Thr)
n.1429T>C
c.*364T>C (n.*364T>C)
c.2072T>C (p.Ile691Thr)
n.2176T>C
c.1955T>C (p.Ile652Thr)
c.1892T>C (p.Ile631Thr)
c.1991T>C (p.Ile664Thr)
n.2413T>C
c.1880T>C (p.Ile627Thr)
n.2393T>C
n.2219T>C
c.1682T>C (p.Ile561Thr)
c.1898T>C (p.Ile633Thr)
c.1916T>C (p.Ile639Thr)
17g.42322407A>TCA399581938STAT3c.1976T>A (p.Ile659Asn)
c.*368T>A (n.*368T>A)
c.1949T>A (p.Ile650Asn)
n.1429T>A
c.*364T>A (n.*364T>A)
c.2072T>A (p.Ile691Asn)
n.2176T>A
c.1955T>A (p.Ile652Asn)
c.1892T>A (p.Ile631Asn)
c.1991T>A (p.Ile664Asn)
n.2413T>A
c.1880T>A (p.Ile627Asn)
n.2393T>A
n.2219T>A
c.1682T>A (p.Ile561Asn)
c.1898T>A (p.Ile633Asn)
c.1916T>A (p.Ile639Asn)
 ClinVar dbSNP
17g.42322408T>ACA399581941STAT3c.1975A>T (p.Ile659Phe)
c.*367A>T (n.*367A>T)
c.1948A>T (p.Ile650Phe)
n.1428A>T
c.*363A>T (n.*363A>T)
c.2071A>T (p.Ile691Phe)
n.2175A>T
c.1954A>T (p.Ile652Phe)
c.1891A>T (p.Ile631Phe)
c.1990A>T (p.Ile664Phe)
n.2412A>T
c.1879A>T (p.Ile627Phe)
n.2392A>T
n.2218A>T
c.1681A>T (p.Ile561Phe)
c.1897A>T (p.Ile633Phe)
c.1915A>T (p.Ile639Phe)
 dbSNP
17g.42322408T>CCA399581944STAT3c.1975A>G (p.Ile659Val)
c.*367A>G (n.*367A>G)
c.1948A>G (p.Ile650Val)
n.1428A>G
c.*363A>G (n.*363A>G)
c.2071A>G (p.Ile691Val)
n.2175A>G
c.1954A>G (p.Ile652Val)
c.1891A>G (p.Ile631Val)
c.1990A>G (p.Ile664Val)
n.2412A>G
c.1879A>G (p.Ile627Val)
n.2392A>G
n.2218A>G
c.1681A>G (p.Ile561Val)
c.1897A>G (p.Ile633Val)
c.1915A>G (p.Ile639Val)
 dbSNP
17g.42322408T>GCA399581946STAT3c.1975A>C (p.Ile659Leu)
c.*367A>C (n.*367A>C)
c.1948A>C (p.Ile650Leu)
n.1428A>C
c.*363A>C (n.*363A>C)
c.2071A>C (p.Ile691Leu)
n.2175A>C
c.1954A>C (p.Ile652Leu)
c.1891A>C (p.Ile631Leu)
c.1990A>C (p.Ile664Leu)
n.2412A>C
c.1879A>C (p.Ile627Leu)
n.2392A>C
n.2218A>C
c.1681A>C (p.Ile561Leu)
c.1897A>C (p.Ile633Leu)
c.1915A>C (p.Ile639Leu)
 dbSNP gnomAD v4 COSMIC
17g.42322409C>ACA399581949STAT3c.1974G>T (p.Lys658Asn)
c.*366G>T (n.*366G>T)
c.1947G>T (p.Lys649Asn)
n.1427G>T
c.*362G>T (n.*362G>T)
c.2070G>T (p.Lys690Asn)
n.2174G>T
c.1953G>T (p.Lys651Asn)
c.1890G>T (p.Lys630Asn)
c.1989G>T (p.Lys663Asn)
n.2411G>T
c.1878G>T (p.Lys626Asn)
n.2391G>T
n.2217G>T
c.1680G>T (p.Lys560Asn)
c.1896G>T (p.Lys632Asn)
c.1914G>T (p.Lys638Asn)
 ClinVar dbSNP COSMIC
17g.42322409C=CA2260430732STAT3c.1974G= (p.Lys658=)
c.*366G= (n.*366G=)
c.1947G= (p.Lys649=)
n.1427G=
c.*362G= (n.*362G=)
c.2070G= (p.Lys690=)
n.2174G=
c.1953G= (p.Lys651=)
c.1890G= (p.Lys630=)
c.1989G= (p.Lys663=)
n.2411G=
c.1878G= (p.Lys626=)
n.2391G=
n.2217G=
c.1680G= (p.Lys560=)
c.1896G= (p.Lys632=)
c.1914G= (p.Lys638=)
17g.42322409C>GCA170590STAT3c.1974G>C (p.Lys658Asn)
c.*366G>C (n.*366G>C)
c.1947G>C (p.Lys649Asn)
n.1427G>C
c.*362G>C (n.*362G>C)
c.2070G>C (p.Lys690Asn)
n.2174G>C
c.1953G>C (p.Lys651Asn)
c.1890G>C (p.Lys630Asn)
c.1989G>C (p.Lys663Asn)
n.2411G>C
c.1878G>C (p.Lys626Asn)
n.2391G>C
n.2217G>C
c.1680G>C (p.Lys560Asn)
c.1896G>C (p.Lys632Asn)
c.1914G>C (p.Lys638Asn)
 ClinVar dbSNP
17g.42322409C>TCA500061082STAT3c.1974G>A (p.Lys658=)
c.*366G>A (n.*366G>A)
c.1947G>A (p.Lys649=)
n.1427G>A
c.*362G>A (n.*362G>A)
c.2070G>A (p.Lys690=)
n.2174G>A
c.1953G>A (p.Lys651=)
c.1890G>A (p.Lys630=)
c.1989G>A (p.Lys663=)
n.2411G>A
c.1878G>A (p.Lys626=)
n.2391G>A
n.2217G>A
c.1680G>A (p.Lys560=)
c.1896G>A (p.Lys632=)
c.1914G>A (p.Lys638=)
 gnomAD v4
17g.42322409_42322411delinsATACA645589635STAT3c.1972_1974delinsTAT (p.Lys658Tyr)
c.*364_*366delinsTAT (n.*364_*366delinsTAT)
c.1945_1947delinsTAT (p.Lys649Tyr)
n.1425_1427delinsTAT
c.*360_*362delinsTAT (n.*360_*362delinsTAT)
c.2068_2070delinsTAT (p.Lys690Tyr)
n.2172_2174delinsTAT
c.1951_1953delinsTAT (p.Lys651Tyr)
c.1888_1890delinsTAT (p.Lys630Tyr)
c.1987_1989delinsTAT (p.Lys663Tyr)
n.2409_2411delinsTAT
c.1876_1878delinsTAT (p.Lys626Tyr)
n.2389_2391delinsTAT
n.2215_2217delinsTAT
c.1678_1680delinsTAT (p.Lys560Tyr)
c.1894_1896delinsTAT (p.Lys632Tyr)
c.1912_1914delinsTAT (p.Lys638Tyr)
 COSMIC
17g.42322409_42322411delinsGTGCA645589636STAT3c.1972_1974delinsCAC (p.Lys658His)
c.*364_*366delinsCAC (n.*364_*366delinsCAC)
c.1945_1947delinsCAC (p.Lys649His)
n.1425_1427delinsCAC
c.*360_*362delinsCAC (n.*360_*362delinsCAC)
c.2068_2070delinsCAC (p.Lys690His)
n.2172_2174delinsCAC
c.1951_1953delinsCAC (p.Lys651His)
c.1888_1890delinsCAC (p.Lys630His)
c.1987_1989delinsCAC (p.Lys663His)
n.2409_2411delinsCAC
c.1876_1878delinsCAC (p.Lys626His)
n.2389_2391delinsCAC
n.2215_2217delinsCAC
c.1678_1680delinsCAC (p.Lys560His)
c.1894_1896delinsCAC (p.Lys632His)
c.1912_1914delinsCAC (p.Lys638His)
 COSMIC
17g.42322410T>ACA399581955STAT3c.1973A>T (p.Lys658Met)
c.*365A>T (n.*365A>T)
c.1946A>T (p.Lys649Met)
n.1426A>T
c.*361A>T (n.*361A>T)
c.2069A>T (p.Lys690Met)
n.2173A>T
c.1952A>T (p.Lys651Met)
c.1889A>T (p.Lys630Met)
c.1988A>T (p.Lys663Met)
n.2410A>T
c.1877A>T (p.Lys626Met)
n.2390A>T
n.2216A>T
c.1679A>T (p.Lys560Met)
c.1895A>T (p.Lys632Met)
c.1913A>T (p.Lys638Met)
17g.42322410T>CCA399581976STAT3c.1973A>G (p.Lys658Arg)
c.*365A>G (n.*365A>G)
c.1946A>G (p.Lys649Arg)
n.1426A>G
c.*361A>G (n.*361A>G)
c.2069A>G (p.Lys690Arg)
n.2173A>G
c.1952A>G (p.Lys651Arg)
c.1889A>G (p.Lys630Arg)
c.1988A>G (p.Lys663Arg)
n.2410A>G
c.1877A>G (p.Lys626Arg)
n.2390A>G
n.2216A>G
c.1679A>G (p.Lys560Arg)
c.1895A>G (p.Lys632Arg)
c.1913A>G (p.Lys638Arg)
 ClinVar dbSNP gnomAD v4 COSMIC
17g.42322410T>GCA399581986STAT3c.1973A>C (p.Lys658Thr)
c.*365A>C (n.*365A>C)
c.1946A>C (p.Lys649Thr)
n.1426A>C
c.*361A>C (n.*361A>C)
c.2069A>C (p.Lys690Thr)
n.2173A>C
c.1952A>C (p.Lys651Thr)
c.1889A>C (p.Lys630Thr)
c.1988A>C (p.Lys663Thr)
n.2410A>C
c.1877A>C (p.Lys626Thr)
n.2390A>C
n.2216A>C
c.1679A>C (p.Lys560Thr)
c.1895A>C (p.Lys632Thr)
c.1913A>C (p.Lys638Thr)
17g.42322410T=CA2260430733STAT3c.1973A= (p.Lys658=)
c.*365A= (n.*365A=)
c.1946A= (p.Lys649=)
n.1426A=
c.*361A= (n.*361A=)
c.2069A= (p.Lys690=)
n.2173A=
c.1952A= (p.Lys651=)
c.1889A= (p.Lys630=)
c.1988A= (p.Lys663=)
n.2410A=
c.1877A= (p.Lys626=)
n.2390A=
n.2216A=
c.1679A= (p.Lys560=)
c.1895A= (p.Lys632=)
c.1913A= (p.Lys638=)
17g.42322411T>ACA399581994STAT3c.1972A>T (p.Lys658Ter)
c.*364A>T (n.*364A>T)
c.1945A>T (p.Lys649Ter)
n.1425A>T
c.*360A>T (n.*360A>T)
c.2068A>T (p.Lys690Ter)
n.2172A>T
c.1951A>T (p.Lys651Ter)
c.1888A>T (p.Lys630Ter)
c.1987A>T (p.Lys663Ter)
n.2409A>T
c.1876A>T (p.Lys626Ter)
n.2389A>T
n.2215A>T
c.1678A>T (p.Lys560Ter)
c.1894A>T (p.Lys632Ter)
c.1912A>T (p.Lys638Ter)
 dbSNP
17g.42322411T>CCA399581996STAT3c.1972A>G (p.Lys658Glu)
c.*364A>G (n.*364A>G)
c.1945A>G (p.Lys649Glu)
n.1425A>G
c.*360A>G (n.*360A>G)
c.2068A>G (p.Lys690Glu)
n.2172A>G
c.1951A>G (p.Lys651Glu)
c.1888A>G (p.Lys630Glu)
c.1987A>G (p.Lys663Glu)
n.2409A>G
c.1876A>G (p.Lys626Glu)
n.2389A>G
n.2215A>G
c.1678A>G (p.Lys560Glu)
c.1894A>G (p.Lys632Glu)
c.1912A>G (p.Lys638Glu)
 dbSNP
17g.42322411T>GCA399581991STAT3c.1972A>C (p.Lys658Gln)
c.*364A>C (n.*364A>C)
c.1945A>C (p.Lys649Gln)
n.1425A>C
c.*360A>C (n.*360A>C)
c.2068A>C (p.Lys690Gln)
n.2172A>C
c.1951A>C (p.Lys651Gln)
c.1888A>C (p.Lys630Gln)
c.1987A>C (p.Lys663Gln)
n.2409A>C
c.1876A>C (p.Lys626Gln)
n.2389A>C
n.2215A>C
c.1678A>C (p.Lys560Gln)
c.1894A>C (p.Lys632Gln)
c.1912A>C (p.Lys638Gln)
 dbSNP
17g.42322411T=CA2260430734STAT3c.1972A= (p.Lys658=)
c.*364A= (n.*364A=)
c.1945A= (p.Lys649=)
n.1425A=
c.*360A= (n.*360A=)
c.2068A= (p.Lys690=)
n.2172A=
c.1951A= (p.Lys651=)
c.1888A= (p.Lys630=)
c.1987A= (p.Lys663=)
n.2409A=
c.1876A= (p.Lys626=)
n.2389A=
n.2215A=
c.1678A= (p.Lys560=)
c.1894A= (p.Lys632=)
c.1912A= (p.Lys638=)
17g.42322412delCA2695225853STAT3c.1971del (p.Tyr657Ter)
c.*363del (n.*363del)
c.1944del (p.Tyr648Ter)
n.1424del
c.*359del (n.*359del)
c.2067del (p.Tyr689Ter)
n.2171del
c.1950del (p.Tyr650Ter)
c.1887del (p.Tyr629Ter)
c.1986del (p.Tyr662Ter)
n.2408del
c.1875del (p.Tyr625Ter)
n.2388del
n.2214del
c.1677del (p.Tyr559Ter)
c.1893del (p.Tyr631Ter)
c.1911del (p.Tyr637Ter)
17g.42322412A>CCA399582003STAT3c.1971T>G (p.Tyr657Ter)
c.*363T>G (n.*363T>G)
c.1944T>G (p.Tyr648Ter)
n.1424T>G
c.*359T>G (n.*359T>G)
c.2067T>G (p.Tyr689Ter)
n.2171T>G
c.1950T>G (p.Tyr650Ter)
c.1887T>G (p.Tyr629Ter)
c.1986T>G (p.Tyr662Ter)
n.2408T>G
c.1875T>G (p.Tyr625Ter)
n.2388T>G
n.2214T>G
c.1677T>G (p.Tyr559Ter)
c.1893T>G (p.Tyr631Ter)
c.1911T>G (p.Tyr637Ter)
 dbSNP
17g.42322412A>GCA500061083STAT3c.1971T>C (p.Tyr657=)
c.*363T>C (n.*363T>C)
c.1944T>C (p.Tyr648=)
n.1424T>C
c.*359T>C (n.*359T>C)
c.2067T>C (p.Tyr689=)
n.2171T>C
c.1950T>C (p.Tyr650=)
c.1887T>C (p.Tyr629=)
c.1986T>C (p.Tyr662=)
n.2408T>C
c.1875T>C (p.Tyr625=)
n.2388T>C
n.2214T>C
c.1677T>C (p.Tyr559=)
c.1893T>C (p.Tyr631=)
c.1911T>C (p.Tyr637=)
 dbSNP
17g.42322412A>TCA399581999STAT3c.1971T>A (p.Tyr657Ter)
c.*363T>A (n.*363T>A)
c.1944T>A (p.Tyr648Ter)
n.1424T>A
c.*359T>A (n.*359T>A)
c.2067T>A (p.Tyr689Ter)
n.2171T>A
c.1950T>A (p.Tyr650Ter)
c.1887T>A (p.Tyr629Ter)
c.1986T>A (p.Tyr662Ter)
n.2408T>A
c.1875T>A (p.Tyr625Ter)
n.2388T>A
n.2214T>A
c.1677T>A (p.Tyr559Ter)
c.1893T>A (p.Tyr631Ter)
c.1911T>A (p.Tyr637Ter)
 dbSNP
17g.42322412_42322414delinsATACA2260430735STAT3c.1969_1971delinsTAT (p.Tyr657=)
c.*361_*363delinsTAT (n.*361_*363delinsTAT)
c.1942_1944delinsTAT (p.Tyr648=)
n.1422_1424delinsTAT
c.*357_*359delinsTAT (n.*357_*359delinsTAT)
c.2065_2067delinsTAT (p.Tyr689=)
n.2169_2171delinsTAT
c.1948_1950delinsTAT (p.Tyr650=)
c.1885_1887delinsTAT (p.Tyr629=)
c.1984_1986delinsTAT (p.Tyr662=)
n.2406_2408delinsTAT
c.1873_1875delinsTAT (p.Tyr625=)
n.2386_2388delinsTAT
n.2212_2214delinsTAT
c.1675_1677delinsTAT (p.Tyr559=)
c.1891_1893delinsTAT (p.Tyr631=)
c.1909_1911delinsTAT (p.Tyr637=)
17g.42322412_42322414delinsCTGCA16620409STAT3c.1969_1971delinsCAG (p.Tyr657Gln)
c.*361_*363delinsCAG (n.*361_*363delinsCAG)
c.1942_1944delinsCAG (p.Tyr648Gln)
n.1422_1424delinsCAG
c.*357_*359delinsCAG (n.*357_*359delinsCAG)
c.2065_2067delinsCAG (p.Tyr689Gln)
n.2169_2171delinsCAG
c.1948_1950delinsCAG (p.Tyr650Gln)
c.1885_1887delinsCAG (p.Tyr629Gln)
c.1984_1986delinsCAG (p.Tyr662Gln)
n.2406_2408delinsCAG
c.1873_1875delinsCAG (p.Tyr625Gln)
n.2386_2388delinsCAG
n.2212_2214delinsCAG
c.1675_1677delinsCAG (p.Tyr559Gln)
c.1891_1893delinsCAG (p.Tyr631Gln)
c.1909_1911delinsCAG (p.Tyr637Gln)
 ClinVar dbSNP
17g.42322412_42322414dupCA645589637STAT3c.1969_1971dup (p.Tyr657_Lys658insTyr)
c.*361_*363dup (n.*361_*363dup)
c.1942_1944dup (p.Tyr648_Lys649insTyr)
n.1422_1424dup
c.*357_*359dup (n.*357_*359dup)
c.2065_2067dup (p.Tyr689_Lys690insTyr)
n.2169_2171dup
c.1948_1950dup (p.Tyr650_Lys651insTyr)
c.1885_1887dup (p.Tyr629_Lys630insTyr)
c.1984_1986dup (p.Tyr662_Lys663insTyr)
n.2406_2408dup
c.1873_1875dup (p.Tyr625_Lys626insTyr)
n.2386_2388dup
n.2212_2214dup
c.1675_1677dup (p.Tyr559_Lys560insTyr)
c.1891_1893dup (p.Tyr631_Lys632insTyr)
c.1909_1911dup (p.Tyr637_Lys638insTyr)
 ClinVar dbSNP gnomAD v3 gnomAD v4 COSMIC
17g.42322413T>ACA399582030STAT3c.1970A>T (p.Tyr657Phe)
c.*362A>T (n.*362A>T)
c.1943A>T (p.Tyr648Phe)
n.1423A>T
c.*358A>T (n.*358A>T)
c.2066A>T (p.Tyr689Phe)
n.2170A>T
c.1949A>T (p.Tyr650Phe)
c.1886A>T (p.Tyr629Phe)
c.1985A>T (p.Tyr662Phe)
n.2407A>T
c.1874A>T (p.Tyr625Phe)
n.2387A>T
n.2213A>T
c.1676A>T (p.Tyr559Phe)
c.1892A>T (p.Tyr631Phe)
c.1910A>T (p.Tyr637Phe)
 dbSNP
17g.42322413T>CCA260546STAT3c.1970A>G (p.Tyr657Cys)
c.*362A>G (n.*362A>G)
c.1943A>G (p.Tyr648Cys)
n.1423A>G
c.*358A>G (n.*358A>G)
c.2066A>G (p.Tyr689Cys)
n.2170A>G
c.1949A>G (p.Tyr650Cys)
c.1886A>G (p.Tyr629Cys)
c.1985A>G (p.Tyr662Cys)
n.2407A>G
c.1874A>G (p.Tyr625Cys)
n.2387A>G
n.2213A>G
c.1676A>G (p.Tyr559Cys)
c.1892A>G (p.Tyr631Cys)
c.1910A>G (p.Tyr637Cys)
 ClinVar dbSNP
17g.42322413T>GCA399582026STAT3c.1970A>C (p.Tyr657Ser)
c.*362A>C (n.*362A>C)
c.1943A>C (p.Tyr648Ser)
n.1423A>C
c.*358A>C (n.*358A>C)
c.2066A>C (p.Tyr689Ser)
n.2170A>C
c.1949A>C (p.Tyr650Ser)
c.1886A>C (p.Tyr629Ser)
c.1985A>C (p.Tyr662Ser)
n.2407A>C
c.1874A>C (p.Tyr625Ser)
n.2387A>C
n.2213A>C
c.1676A>C (p.Tyr559Ser)
c.1892A>C (p.Tyr631Ser)
c.1910A>C (p.Tyr637Ser)
 dbSNP
17g.42322413T=CA2260430736STAT3c.1970A= (p.Tyr657=)
c.*362A= (n.*362A=)
c.1943A= (p.Tyr648=)
n.1423A=
c.*358A= (n.*358A=)
c.2066A= (p.Tyr689=)
n.2170A=
c.1949A= (p.Tyr650=)
c.1886A= (p.Tyr629=)
c.1985A= (p.Tyr662=)
n.2407A=
c.1874A= (p.Tyr625=)
n.2387A=
n.2213A=
c.1676A= (p.Tyr559=)
c.1892A= (p.Tyr631=)
c.1910A= (p.Tyr637=)
17g.42322414A>CCA399582031STAT3c.1969T>G (p.Tyr657Asp)
c.*361T>G (n.*361T>G)
c.1942T>G (p.Tyr648Asp)
n.1422T>G
c.*357T>G (n.*357T>G)
c.2065T>G (p.Tyr689Asp)
n.2169T>G
c.1948T>G (p.Tyr650Asp)
c.1885T>G (p.Tyr629Asp)
c.1984T>G (p.Tyr662Asp)
n.2406T>G
c.1873T>G (p.Tyr625Asp)
n.2386T>G
n.2212T>G
c.1675T>G (p.Tyr559Asp)
c.1891T>G (p.Tyr631Asp)
c.1909T>G (p.Tyr637Asp)
17g.42322414A>GCA399582032STAT3c.1969T>C (p.Tyr657His)
c.*361T>C (n.*361T>C)
c.1942T>C (p.Tyr648His)
n.1422T>C
c.*357T>C (n.*357T>C)
c.2065T>C (p.Tyr689His)
n.2169T>C
c.1948T>C (p.Tyr650His)
c.1885T>C (p.Tyr629His)
c.1984T>C (p.Tyr662His)
n.2406T>C
c.1873T>C (p.Tyr625His)
n.2386T>C
n.2212T>C
c.1675T>C (p.Tyr559His)
c.1891T>C (p.Tyr631His)
c.1909T>C (p.Tyr637His)
17g.42322414A>TCA399582033STAT3c.1969T>A (p.Tyr657Asn)
c.*361T>A (n.*361T>A)
c.1942T>A (p.Tyr648Asn)
n.1422T>A
c.*357T>A (n.*357T>A)
c.2065T>A (p.Tyr689Asn)
n.2169T>A
c.1948T>A (p.Tyr650Asn)
c.1885T>A (p.Tyr629Asn)
c.1984T>A (p.Tyr662Asn)
n.2406T>A
c.1873T>A (p.Tyr625Asn)
n.2386T>A
n.2212T>A
c.1675T>A (p.Tyr559Asn)
c.1891T>A (p.Tyr631Asn)
c.1909T>A (p.Tyr637Asn)
 dbSNP
17g.42322414_42322415insAAACA2637932881STAT3c.1969_1970insTTT (p.Gly656_Tyr657insPhe)
c.*361_*362insTTT (n.*361_*362insTTT)
c.1942_1943insTTT (p.Gly647_Tyr648insPhe)
n.1422_1423insTTT
c.*357_*358insTTT (n.*357_*358insTTT)
c.2065_2066insTTT (p.Gly688_Tyr689insPhe)
n.2169_2170insTTT
c.1948_1949insTTT (p.Gly649_Tyr650insPhe)
c.1885_1886insTTT (p.Gly628_Tyr629insPhe)
c.1984_1985insTTT (p.Gly661_Tyr662insPhe)
n.2406_2407insTTT
c.1873_1874insTTT (p.Gly624_Tyr625insPhe)
n.2386_2387insTTT
n.2212_2213insTTT
c.1675_1676insTTT (p.Gly558_Tyr559insPhe)
c.1891_1892insTTT (p.Gly630_Tyr631insPhe)
c.1909_1910insTTT (p.Gly636_Tyr637insPhe)
 ClinVar gnomAD v4
17g.42322415G>ACA8575180STAT3c.1968C>T (p.Gly656=)
c.*360C>T (n.*360C>T)
c.1941C>T (p.Gly647=)
n.1421C>T
c.*356C>T (n.*356C>T)
c.2064C>T (p.Gly688=)
n.2168C>T
c.1947C>T (p.Gly649=)
c.1884C>T (p.Gly628=)
c.1983C>T (p.Gly661=)
n.2405C>T
c.1872C>T (p.Gly624=)
n.2385C>T
n.2211C>T
c.1674C>T (p.Gly558=)
c.1890C>T (p.Gly630=)
c.1908C>T (p.Gly636=)
 ClinVar dbSNP ExAC gnomAD v2 gnomAD v4
17g.42322415G>CCA500061084STAT3c.1968C>G (p.Gly656=)
c.*360C>G (n.*360C>G)
c.1941C>G (p.Gly647=)
n.1421C>G
c.*356C>G (n.*356C>G)
c.2064C>G (p.Gly688=)
n.2168C>G
c.1947C>G (p.Gly649=)
c.1884C>G (p.Gly628=)
c.1983C>G (p.Gly661=)
n.2405C>G
c.1872C>G (p.Gly624=)
n.2385C>G
n.2211C>G
c.1674C>G (p.Gly558=)
c.1890C>G (p.Gly630=)
c.1908C>G (p.Gly636=)
 dbSNP
17g.42322415G=CA2260430737STAT3c.1968C= (p.Gly656=)
c.*360C= (n.*360C=)
c.1941C= (p.Gly647=)
n.1421C=
c.*356C= (n.*356C=)
c.2064C= (p.Gly688=)
n.2168C=
c.1947C= (p.Gly649=)
c.1884C= (p.Gly628=)
c.1983C= (p.Gly661=)
n.2405C=
c.1872C= (p.Gly624=)
n.2385C=
n.2211C=
c.1674C= (p.Gly558=)
c.1890C= (p.Gly630=)
c.1908C= (p.Gly636=)
17g.42322415G>TCA500061085STAT3c.1968C>A (p.Gly656=)
c.*360C>A (n.*360C>A)
c.1941C>A (p.Gly647=)
n.1421C>A
c.*356C>A (n.*356C>A)
c.2064C>A (p.Gly688=)
n.2168C>A
c.1947C>A (p.Gly649=)
c.1884C>A (p.Gly628=)
c.1983C>A (p.Gly661=)
n.2405C>A
c.1872C>A (p.Gly624=)
n.2385C>A
n.2211C>A
c.1674C>A (p.Gly558=)
c.1890C>A (p.Gly630=)
c.1908C>A (p.Gly636=)
 dbSNP gnomAD v4
17g.42322415delinsAAAACA645589638STAT3c.1968delinsTTTT (p.Gly656_Tyr657insPhe)
c.*360delinsTTTT (n.*360delinsTTTT)
c.1941delinsTTTT (p.Gly647_Tyr648insPhe)
n.1421delinsTTTT
c.*356delinsTTTT (n.*356delinsTTTT)
c.2064delinsTTTT (p.Gly688_Tyr689insPhe)
n.2168delinsTTTT
c.1947delinsTTTT (p.Gly649_Tyr650insPhe)
c.1884delinsTTTT (p.Gly628_Tyr629insPhe)
c.1983delinsTTTT (p.Gly661_Tyr662insPhe)
n.2405delinsTTTT
c.1872delinsTTTT (p.Gly624_Tyr625insPhe)
n.2385delinsTTTT
n.2211delinsTTTT
c.1674delinsTTTT (p.Gly558_Tyr559insPhe)
c.1890delinsTTTT (p.Gly630_Tyr631insPhe)
c.1908delinsTTTT (p.Gly636_Tyr637insPhe)
 COSMIC
17g.42322416C>ACA399582036STAT3c.1967G>T (p.Gly656Val)
c.*359G>T (n.*359G>T)
c.1940G>T (p.Gly647Val)
n.1420G>T
c.*355G>T (n.*355G>T)
c.2063G>T (p.Gly688Val)
n.2167G>T
c.1946G>T (p.Gly649Val)
c.1883G>T (p.Gly628Val)
c.1982G>T (p.Gly661Val)
n.2404G>T
c.1871G>T (p.Gly624Val)
n.2384G>T
n.2210G>T
c.1673G>T (p.Gly558Val)
c.1889G>T (p.Gly630Val)
c.1907G>T (p.Gly636Val)
 dbSNP
17g.42322416C>GCA399582040STAT3c.1967G>C (p.Gly656Ala)
c.*359G>C (n.*359G>C)
c.1940G>C (p.Gly647Ala)
n.1420G>C
c.*355G>C (n.*355G>C)
c.2063G>C (p.Gly688Ala)
n.2167G>C
c.1946G>C (p.Gly649Ala)
c.1883G>C (p.Gly628Ala)
c.1982G>C (p.Gly661Ala)
n.2404G>C
c.1871G>C (p.Gly624Ala)
n.2384G>C
n.2210G>C
c.1673G>C (p.Gly558Ala)
c.1889G>C (p.Gly630Ala)
c.1907G>C (p.Gly636Ala)
 dbSNP
17g.42322416C>TCA399582048STAT3c.1967G>A (p.Gly656Asp)
c.*359G>A (n.*359G>A)
c.1940G>A (p.Gly647Asp)
n.1420G>A
c.*355G>A (n.*355G>A)
c.2063G>A (p.Gly688Asp)
n.2167G>A
c.1946G>A (p.Gly649Asp)
c.1883G>A (p.Gly628Asp)
c.1982G>A (p.Gly661Asp)
n.2404G>A
c.1871G>A (p.Gly624Asp)
n.2384G>A
n.2210G>A
c.1673G>A (p.Gly558Asp)
c.1889G>A (p.Gly630Asp)
c.1907G>A (p.Gly636Asp)
 dbSNP COSMIC
17g.42322417C>ACA399582051STAT3c.1966G>T (p.Gly656Cys)
c.*358G>T (n.*358G>T)
c.1939G>T (p.Gly647Cys)
n.1419G>T
c.*354G>T (n.*354G>T)
c.2062G>T (p.Gly688Cys)
n.2166G>T
c.1945G>T (p.Gly649Cys)
c.1882G>T (p.Gly628Cys)
c.1981G>T (p.Gly661Cys)
n.2403G>T
c.1870G>T (p.Gly624Cys)
n.2383G>T
n.2209G>T
c.1672G>T (p.Gly558Cys)
c.1888G>T (p.Gly630Cys)
c.1906G>T (p.Gly636Cys)
 dbSNP
17g.42322417C>GCA399582070STAT3c.1966G>C (p.Gly656Arg)
c.*358G>C (n.*358G>C)
c.1939G>C (p.Gly647Arg)
n.1419G>C
c.*354G>C (n.*354G>C)
c.2062G>C (p.Gly688Arg)
n.2166G>C
c.1945G>C (p.Gly649Arg)
c.1882G>C (p.Gly628Arg)
c.1981G>C (p.Gly661Arg)
n.2403G>C
c.1870G>C (p.Gly624Arg)
n.2383G>C
n.2209G>C
c.1672G>C (p.Gly558Arg)
c.1888G>C (p.Gly630Arg)
c.1906G>C (p.Gly636Arg)
 ClinVar dbSNP
17g.42322417C>TCA399582074STAT3c.1966G>A (p.Gly656Ser)
c.*358G>A (n.*358G>A)
c.1939G>A (p.Gly647Ser)
n.1419G>A
c.*354G>A (n.*354G>A)
c.2062G>A (p.Gly688Ser)
n.2166G>A
c.1945G>A (p.Gly649Ser)
c.1882G>A (p.Gly628Ser)
c.1981G>A (p.Gly661Ser)
n.2403G>A
c.1870G>A (p.Gly624Ser)
n.2383G>A
n.2209G>A
c.1672G>A (p.Gly558Ser)
c.1888G>A (p.Gly630Ser)
c.1906G>A (p.Gly636Ser)
 dbSNP
17g.42322418C>ACA399582089STAT3c.1965G>T (p.Met655Ile)
c.*357G>T (n.*357G>T)
c.1938G>T (p.Met646Ile)
n.1418G>T
c.*353G>T (n.*353G>T)
c.2061G>T (p.Met687Ile)
n.2165G>T
c.1944G>T (p.Met648Ile)
c.1881G>T (p.Met627Ile)
c.1980G>T (p.Met660Ile)
n.2402G>T
c.1869G>T (p.Met623Ile)
n.2382G>T
n.2208G>T
c.1671G>T (p.Met557Ile)
c.1887G>T (p.Met629Ile)
c.1905G>T (p.Met635Ile)
 dbSNP
17g.42322418C>GCA399582086STAT3c.1965G>C (p.Met655Ile)
c.*357G>C (n.*357G>C)
c.1938G>C (p.Met646Ile)
n.1418G>C
c.*353G>C (n.*353G>C)
c.2061G>C (p.Met687Ile)
n.2165G>C
c.1944G>C (p.Met648Ile)
c.1881G>C (p.Met627Ile)
c.1980G>C (p.Met660Ile)
n.2402G>C
c.1869G>C (p.Met623Ile)
n.2382G>C
n.2208G>C
c.1671G>C (p.Met557Ile)
c.1887G>C (p.Met629Ile)
c.1905G>C (p.Met635Ile)
 dbSNP
17g.42322418C>TCA399582088STAT3c.1965G>A (p.Met655Ile)
c.*357G>A (n.*357G>A)
c.1938G>A (p.Met646Ile)
n.1418G>A
c.*353G>A (n.*353G>A)
c.2061G>A (p.Met687Ile)
n.2165G>A
c.1944G>A (p.Met648Ile)
c.1881G>A (p.Met627Ile)
c.1980G>A (p.Met660Ile)
n.2402G>A
c.1869G>A (p.Met623Ile)
n.2382G>A
n.2208G>A
c.1671G>A (p.Met557Ile)
c.1887G>A (p.Met629Ile)
c.1905G>A (p.Met635Ile)
 dbSNP COSMIC
17g.42322419A>CCA399582090STAT3c.1964T>G (p.Met655Arg)
c.*356T>G (n.*356T>G)
c.1937T>G (p.Met646Arg)
n.1417T>G
c.*352T>G (n.*352T>G)
c.2060T>G (p.Met687Arg)
n.2164T>G
c.1943T>G (p.Met648Arg)
c.1880T>G (p.Met627Arg)
c.1979T>G (p.Met660Arg)
n.2401T>G
c.1868T>G (p.Met623Arg)
n.2381T>G
n.2207T>G
c.1670T>G (p.Met557Arg)
c.1886T>G (p.Met629Arg)
c.1904T>G (p.Met635Arg)
17g.42322419A>GCA399582092STAT3c.1964T>C (p.Met655Thr)
c.*356T>C (n.*356T>C)
c.1937T>C (p.Met646Thr)
n.1417T>C
c.*352T>C (n.*352T>C)
c.2060T>C (p.Met687Thr)
n.2164T>C
c.1943T>C (p.Met648Thr)
c.1880T>C (p.Met627Thr)
c.1979T>C (p.Met660Thr)
n.2401T>C
c.1868T>C (p.Met623Thr)
n.2381T>C
n.2207T>C
c.1670T>C (p.Met557Thr)
c.1886T>C (p.Met629Thr)
c.1904T>C (p.Met635Thr)
 dbSNP
17g.42322419A>TCA399582094STAT3c.1964T>A (p.Met655Lys)
c.*356T>A (n.*356T>A)
c.1937T>A (p.Met646Lys)
n.1417T>A
c.*352T>A (n.*352T>A)
c.2060T>A (p.Met687Lys)
n.2164T>A
c.1943T>A (p.Met648Lys)
c.1880T>A (p.Met627Lys)
c.1979T>A (p.Met660Lys)
n.2401T>A
c.1868T>A (p.Met623Lys)
n.2381T>A
n.2207T>A
c.1670T>A (p.Met557Lys)
c.1886T>A (p.Met629Lys)
c.1904T>A (p.Met635Lys)
 dbSNP COSMIC
17g.42322424_42322426delCA2695225854STAT3c.1962_1964del (p.Ile654del)
c.*354_*356del (n.*354_*356del)
c.1935_1937del (p.Ile645del)
n.1415_1417del
c.*350_*352del (n.*350_*352del)
c.2058_2060del (p.Ile686del)
n.2162_2164del
c.1941_1943del (p.Ile647del)
c.1878_1880del (p.Ile626del)
c.1977_1979del (p.Ile659del)
n.2399_2401del
c.1866_1868del (p.Ile622del)
n.2379_2381del
n.2205_2207del
c.1668_1670del (p.Ile556del)
c.1884_1886del (p.Ile628del)
c.1902_1904del (p.Ile634del)
17g.42322420T>ACA399582099STAT3c.1963A>T (p.Met655Leu)
c.*355A>T (n.*355A>T)
c.1936A>T (p.Met646Leu)
n.1416A>T
c.*351A>T (n.*351A>T)
c.2059A>T (p.Met687Leu)
n.2163A>T
c.1942A>T (p.Met648Leu)
c.1879A>T (p.Met627Leu)
c.1978A>T (p.Met660Leu)
n.2400A>T
c.1867A>T (p.Met623Leu)
n.2380A>T
n.2206A>T
c.1669A>T (p.Met557Leu)
c.1885A>T (p.Met629Leu)
c.1903A>T (p.Met635Leu)
 ClinVar dbSNP
17g.42322420T>CCA399582105STAT3c.1963A>G (p.Met655Val)
c.*355A>G (n.*355A>G)
c.1936A>G (p.Met646Val)
n.1416A>G
c.*351A>G (n.*351A>G)
c.2059A>G (p.Met687Val)
n.2163A>G
c.1942A>G (p.Met648Val)
c.1879A>G (p.Met627Val)
c.1978A>G (p.Met660Val)
n.2400A>G
c.1867A>G (p.Met623Val)
n.2380A>G
n.2206A>G
c.1669A>G (p.Met557Val)
c.1885A>G (p.Met629Val)
c.1903A>G (p.Met635Val)
 dbSNP
17g.42322420T>GCA399582132STAT3c.1963A>C (p.Met655Leu)
c.*355A>C (n.*355A>C)
c.1936A>C (p.Met646Leu)
n.1416A>C
c.*351A>C (n.*351A>C)
c.2059A>C (p.Met687Leu)
n.2163A>C
c.1942A>C (p.Met648Leu)
c.1879A>C (p.Met627Leu)
c.1978A>C (p.Met660Leu)
n.2400A>C
c.1867A>C (p.Met623Leu)
n.2380A>C
n.2206A>C
c.1669A>C (p.Met557Leu)
c.1885A>C (p.Met629Leu)
c.1903A>C (p.Met635Leu)
17g.42322420T=CA2260430738STAT3c.1963A= (p.Met655=)
c.*355A= (n.*355A=)
c.1936A= (p.Met646=)
n.1416A=
c.*351A= (n.*351A=)
c.2059A= (p.Met687=)
n.2163A=
c.1942A= (p.Met648=)
c.1879A= (p.Met627=)
c.1978A= (p.Met660=)
n.2400A=
c.1867A= (p.Met623=)
n.2380A=
n.2206A=
c.1669A= (p.Met557=)
c.1885A= (p.Met629=)
c.1903A= (p.Met635=)
17g.42322421G>ACA8575181STAT3c.1962C>T (p.Ile654=)
c.*354C>T (n.*354C>T)
c.1935C>T (p.Ile645=)
n.1415C>T
c.*350C>T (n.*350C>T)
c.2058C>T (p.Ile686=)
n.2162C>T
c.1941C>T (p.Ile647=)
c.1878C>T (p.Ile626=)
c.1977C>T (p.Ile659=)
n.2399C>T
c.1866C>T (p.Ile622=)
n.2379C>T
n.2205C>T
c.1668C>T (p.Ile556=)
c.1884C>T (p.Ile628=)
c.1902C>T (p.Ile634=)
 dbSNP ExAC gnomAD v2 gnomAD v4
17g.42322421G>CCA399582138STAT3c.1962C>G (p.Ile654Met)
c.*354C>G (n.*354C>G)
c.1935C>G (p.Ile645Met)
n.1415C>G
c.*350C>G (n.*350C>G)
c.2058C>G (p.Ile686Met)
n.2162C>G
c.1941C>G (p.Ile647Met)
c.1878C>G (p.Ile626Met)
c.1977C>G (p.Ile659Met)
n.2399C>G
c.1866C>G (p.Ile622Met)
n.2379C>G
n.2205C>G
c.1668C>G (p.Ile556Met)
c.1884C>G (p.Ile628Met)
c.1902C>G (p.Ile634Met)
 dbSNP
17g.42322421G=CA2260430739STAT3c.1962C= (p.Ile654=)
c.*354C= (n.*354C=)
c.1935C= (p.Ile645=)
n.1415C=
c.*350C= (n.*350C=)
c.2058C= (p.Ile686=)
n.2162C=
c.1941C= (p.Ile647=)
c.1878C= (p.Ile626=)
c.1977C= (p.Ile659=)
n.2399C=
c.1866C= (p.Ile622=)
n.2379C=
n.2205C=
c.1668C= (p.Ile556=)
c.1884C= (p.Ile628=)
c.1902C= (p.Ile634=)
17g.42322421G>TCA500061086STAT3c.1962C>A (p.Ile654=)
c.*354C>A (n.*354C>A)
c.1935C>A (p.Ile645=)
n.1415C>A
c.*350C>A (n.*350C>A)
c.2058C>A (p.Ile686=)
n.2162C>A
c.1941C>A (p.Ile647=)
c.1878C>A (p.Ile626=)
c.1977C>A (p.Ile659=)
n.2399C>A
c.1866C>A (p.Ile622=)
n.2379C>A
n.2205C>A
c.1668C>A (p.Ile556=)
c.1884C>A (p.Ile628=)
c.1902C>A (p.Ile634=)
 dbSNP
17g.42322422A>CCA399582146STAT3c.1961T>G (p.Ile654Ser)
c.*353T>G (n.*353T>G)
c.1934T>G (p.Ile645Ser)
n.1414T>G
c.*349T>G (n.*349T>G)
c.2057T>G (p.Ile686Ser)
n.2161T>G
c.1940T>G (p.Ile647Ser)
c.1877T>G (p.Ile626Ser)
c.1976T>G (p.Ile659Ser)
n.2398T>G
c.1865T>G (p.Ile622Ser)
n.2378T>G
n.2204T>G
c.1667T>G (p.Ile556Ser)
c.1883T>G (p.Ile628Ser)
c.1901T>G (p.Ile634Ser)
17g.42322422A>GCA399582149STAT3c.1961T>C (p.Ile654Thr)
c.*353T>C (n.*353T>C)
c.1934T>C (p.Ile645Thr)
n.1414T>C
c.*349T>C (n.*349T>C)
c.2057T>C (p.Ile686Thr)
n.2161T>C
c.1940T>C (p.Ile647Thr)
c.1877T>C (p.Ile626Thr)
c.1976T>C (p.Ile659Thr)
n.2398T>C
c.1865T>C (p.Ile622Thr)
n.2378T>C
n.2204T>C
c.1667T>C (p.Ile556Thr)
c.1883T>C (p.Ile628Thr)
c.1901T>C (p.Ile634Thr)
 dbSNP COSMIC
17g.42322422A>TCA399582152STAT3c.1961T>A (p.Ile654Asn)
c.*353T>A (n.*353T>A)
c.1934T>A (p.Ile645Asn)
n.1414T>A
c.*349T>A (n.*349T>A)
c.2057T>A (p.Ile686Asn)
n.2161T>A
c.1940T>A (p.Ile647Asn)
c.1877T>A (p.Ile626Asn)
c.1976T>A (p.Ile659Asn)
n.2398T>A
c.1865T>A (p.Ile622Asn)
n.2378T>A
n.2204T>A
c.1667T>A (p.Ile556Asn)
c.1883T>A (p.Ile628Asn)
c.1901T>A (p.Ile634Asn)
 dbSNP
17g.42322423T>ACA399582159STAT3c.1960A>T (p.Ile654Phe)
c.*352A>T (n.*352A>T)
c.1933A>T (p.Ile645Phe)
n.1413A>T
c.*348A>T (n.*348A>T)
c.2056A>T (p.Ile686Phe)
n.2160A>T
c.1939A>T (p.Ile647Phe)
c.1876A>T (p.Ile626Phe)
c.1975A>T (p.Ile659Phe)
n.2397A>T
c.1864A>T (p.Ile622Phe)
n.2377A>T
n.2203A>T
c.1666A>T (p.Ile556Phe)
c.1882A>T (p.Ile628Phe)
c.1900A>T (p.Ile634Phe)
 dbSNP
17g.42322423T>CCA399582162STAT3c.1960A>G (p.Ile654Val)
c.*352A>G (n.*352A>G)
c.1933A>G (p.Ile645Val)
n.1413A>G
c.*348A>G (n.*348A>G)
c.2056A>G (p.Ile686Val)
n.2160A>G
c.1939A>G (p.Ile647Val)
c.1876A>G (p.Ile626Val)
c.1975A>G (p.Ile659Val)
n.2397A>G
c.1864A>G (p.Ile622Val)
n.2377A>G
n.2203A>G
c.1666A>G (p.Ile556Val)
c.1882A>G (p.Ile628Val)
c.1900A>G (p.Ile634Val)
 dbSNP
17g.42322423T>GCA399582155STAT3c.1960A>C (p.Ile654Leu)
c.*352A>C (n.*352A>C)
c.1933A>C (p.Ile645Leu)
n.1413A>C
c.*348A>C (n.*348A>C)
c.2056A>C (p.Ile686Leu)
n.2160A>C
c.1939A>C (p.Ile647Leu)
c.1876A>C (p.Ile626Leu)
c.1975A>C (p.Ile659Leu)
n.2397A>C
c.1864A>C (p.Ile622Leu)
n.2377A>C
n.2203A>C
c.1666A>C (p.Ile556Leu)
c.1882A>C (p.Ile628Leu)
c.1900A>C (p.Ile634Leu)
17g.42322424G>ACA500061088STAT3c.1959C>T (p.Ile653=)
c.*351C>T (n.*351C>T)
c.1932C>T (p.Ile644=)
n.1412C>T
c.*347C>T (n.*347C>T)
c.2055C>T (p.Ile685=)
n.2159C>T
c.1938C>T (p.Ile646=)
c.1875C>T (p.Ile625=)
c.1974C>T (p.Ile658=)
n.2396C>T
c.1863C>T (p.Ile621=)
n.2376C>T
n.2202C>T
c.1665C>T (p.Ile555=)
c.1881C>T (p.Ile627=)
c.1899C>T (p.Ile633=)
 dbSNP gnomAD v4
17g.42322424G>CCA399582164STAT3c.1959C>G (p.Ile653Met)
c.*351C>G (n.*351C>G)
c.1932C>G (p.Ile644Met)
n.1412C>G
c.*347C>G (n.*347C>G)
c.2055C>G (p.Ile685Met)
n.2159C>G
c.1938C>G (p.Ile646Met)
c.1875C>G (p.Ile625Met)
c.1974C>G (p.Ile658Met)
n.2396C>G
c.1863C>G (p.Ile621Met)
n.2376C>G
n.2202C>G
c.1665C>G (p.Ile555Met)
c.1881C>G (p.Ile627Met)
c.1899C>G (p.Ile633Met)
 dbSNP
17g.42322424G>TCA500061087STAT3c.1959C>A (p.Ile653=)
c.*351C>A (n.*351C>A)
c.1932C>A (p.Ile644=)
n.1412C>A
c.*347C>A (n.*347C>A)
c.2055C>A (p.Ile685=)
n.2159C>A
c.1938C>A (p.Ile646=)
c.1875C>A (p.Ile625=)
c.1974C>A (p.Ile658=)
n.2396C>A
c.1863C>A (p.Ile621=)
n.2376C>A
n.2202C>A
c.1665C>A (p.Ile555=)
c.1881C>A (p.Ile627=)
c.1899C>A (p.Ile633=)
 dbSNP
17g.42322425A>CCA399582168STAT3c.1958T>G (p.Ile653Ser)
c.*350T>G (n.*350T>G)
c.1931T>G (p.Ile644Ser)
n.1411T>G
c.*346T>G (n.*346T>G)
c.2054T>G (p.Ile685Ser)
n.2158T>G
c.1937T>G (p.Ile646Ser)
c.1874T>G (p.Ile625Ser)
c.1973T>G (p.Ile658Ser)
n.2395T>G
c.1862T>G (p.Ile621Ser)
n.2375T>G
n.2201T>G
c.1664T>G (p.Ile555Ser)
c.1880T>G (p.Ile627Ser)
c.1898T>G (p.Ile633Ser)
 dbSNP
17g.42322425A>GCA399582169STAT3c.1958T>C (p.Ile653Thr)
c.*350T>C (n.*350T>C)
c.1931T>C (p.Ile644Thr)
n.1411T>C
c.*346T>C (n.*346T>C)
c.2054T>C (p.Ile685Thr)
n.2158T>C
c.1937T>C (p.Ile646Thr)
c.1874T>C (p.Ile625Thr)
c.1973T>C (p.Ile658Thr)
n.2395T>C
c.1862T>C (p.Ile621Thr)
n.2375T>C
n.2201T>C
c.1664T>C (p.Ile555Thr)
c.1880T>C (p.Ile627Thr)
c.1898T>C (p.Ile633Thr)
17g.42322425A>TCA399582170STAT3c.1958T>A (p.Ile653Asn)
c.*350T>A (n.*350T>A)
c.1931T>A (p.Ile644Asn)
n.1411T>A
c.*346T>A (n.*346T>A)
c.2054T>A (p.Ile685Asn)
n.2158T>A
c.1937T>A (p.Ile646Asn)
c.1874T>A (p.Ile625Asn)
c.1973T>A (p.Ile658Asn)
n.2395T>A
c.1862T>A (p.Ile621Asn)
n.2375T>A
n.2201T>A
c.1664T>A (p.Ile555Asn)
c.1880T>A (p.Ile627Asn)
c.1898T>A (p.Ile633Asn)
 dbSNP
17g.42322426T>ACA399582171STAT3c.1957A>T (p.Ile653Phe)
c.*349A>T (n.*349A>T)
c.1930A>T (p.Ile644Phe)
n.1410A>T
c.*345A>T (n.*345A>T)
c.2053A>T (p.Ile685Phe)
n.2157A>T
c.1936A>T (p.Ile646Phe)
c.1873A>T (p.Ile625Phe)
c.1972A>T (p.Ile658Phe)
n.2394A>T
c.1861A>T (p.Ile621Phe)
n.2374A>T
n.2200A>T
c.1663A>T (p.Ile555Phe)
c.1879A>T (p.Ile627Phe)
c.1897A>T (p.Ile633Phe)
 dbSNP COSMIC
17g.42322426T>CCA399582173STAT3c.1957A>G (p.Ile653Val)
c.*349A>G (n.*349A>G)
c.1930A>G (p.Ile644Val)
n.1410A>G
c.*345A>G (n.*345A>G)
c.2053A>G (p.Ile685Val)
n.2157A>G
c.1936A>G (p.Ile646Val)
c.1873A>G (p.Ile625Val)
c.1972A>G (p.Ile658Val)
n.2394A>G
c.1861A>G (p.Ile621Val)
n.2374A>G
n.2200A>G
c.1663A>G (p.Ile555Val)
c.1879A>G (p.Ile627Val)
c.1897A>G (p.Ile633Val)
 COSMIC
17g.42322426T>GCA399582175STAT3c.1957A>C (p.Ile653Leu)
c.*349A>C (n.*349A>C)
c.1930A>C (p.Ile644Leu)
n.1410A>C
c.*345A>C (n.*345A>C)
c.2053A>C (p.Ile685Leu)
n.2157A>C
c.1936A>C (p.Ile646Leu)
c.1873A>C (p.Ile625Leu)
c.1972A>C (p.Ile658Leu)
n.2394A>C
c.1861A>C (p.Ile621Leu)
n.2374A>C
n.2200A>C
c.1663A>C (p.Ile555Leu)
c.1879A>C (p.Ile627Leu)
c.1897A>C (p.Ile633Leu)
 dbSNP
17g.42322427T>ACA399582181STAT3c.1956A>T (p.Glu652Asp)
c.*348A>T (n.*348A>T)
c.1929A>T (p.Glu643Asp)
n.1409A>T
c.*344A>T (n.*344A>T)
c.2052A>T (p.Glu684Asp)
n.2156A>T
c.1935A>T (p.Glu645Asp)
c.1872A>T (p.Glu624Asp)
c.1971A>T (p.Glu657Asp)
n.2393A>T
c.1860A>T (p.Glu620Asp)
n.2373A>T
n.2199A>T
c.1662A>T (p.Glu554Asp)
c.1878A>T (p.Glu626Asp)
c.1896A>T (p.Glu632Asp)
 dbSNP
17g.42322427T>CCA500061089STAT3c.1956A>G (p.Glu652=)
c.*348A>G (n.*348A>G)
c.1929A>G (p.Glu643=)
n.1409A>G
c.*344A>G (n.*344A>G)
c.2052A>G (p.Glu684=)
n.2156A>G
c.1935A>G (p.Glu645=)
c.1872A>G (p.Glu624=)
c.1971A>G (p.Glu657=)
n.2393A>G
c.1860A>G (p.Glu620=)
n.2373A>G
n.2199A>G
c.1662A>G (p.Glu554=)
c.1878A>G (p.Glu626=)
c.1896A>G (p.Glu632=)
17g.42322427T>GCA399582184STAT3c.1956A>C (p.Glu652Asp)
c.*348A>C (n.*348A>C)
c.1929A>C (p.Glu643Asp)
n.1409A>C
c.*344A>C (n.*344A>C)
c.2052A>C (p.Glu684Asp)
n.2156A>C
c.1935A>C (p.Glu645Asp)
c.1872A>C (p.Glu624Asp)
c.1971A>C (p.Glu657Asp)
n.2393A>C
c.1860A>C (p.Glu620Asp)
n.2373A>C
n.2199A>C
c.1662A>C (p.Glu554Asp)
c.1878A>C (p.Glu626Asp)
c.1896A>C (p.Glu632Asp)
17g.42322428T>ACA399582187STAT3c.1955A>T (p.Glu652Val)
c.*347A>T (n.*347A>T)
c.1928A>T (p.Glu643Val)
n.1408A>T
c.*343A>T (n.*343A>T)
c.2051A>T (p.Glu684Val)
n.2155A>T
c.1934A>T (p.Glu645Val)
c.1871A>T (p.Glu624Val)
c.1970A>T (p.Glu657Val)
n.2392A>T
c.1859A>T (p.Glu620Val)
n.2372A>T
n.2198A>T
c.1661A>T (p.Glu554Val)
c.1877A>T (p.Glu626Val)
c.1895A>T (p.Glu632Val)
 dbSNP
17g.42322428T>CCA399582191STAT3c.1955A>G (p.Glu652Gly)
c.*347A>G (n.*347A>G)
c.1928A>G (p.Glu643Gly)
n.1408A>G
c.*343A>G (n.*343A>G)
c.2051A>G (p.Glu684Gly)
n.2155A>G
c.1934A>G (p.Glu645Gly)
c.1871A>G (p.Glu624Gly)
c.1970A>G (p.Glu657Gly)
n.2392A>G
c.1859A>G (p.Glu620Gly)
n.2372A>G
n.2198A>G
c.1661A>G (p.Glu554Gly)
c.1877A>G (p.Glu626Gly)
c.1895A>G (p.Glu632Gly)
 ClinVar
17g.42322428T>GCA399582195STAT3c.1955A>C (p.Glu652Ala)
c.*347A>C (n.*347A>C)
c.1928A>C (p.Glu643Ala)
n.1408A>C
c.*343A>C (n.*343A>C)
c.2051A>C (p.Glu684Ala)
n.2155A>C
c.1934A>C (p.Glu645Ala)
c.1871A>C (p.Glu624Ala)
c.1970A>C (p.Glu657Ala)
n.2392A>C
c.1859A>C (p.Glu620Ala)
n.2372A>C
n.2198A>C
c.1661A>C (p.Glu554Ala)
c.1877A>C (p.Glu626Ala)
c.1895A>C (p.Glu632Ala)
17g.42322429C>ACA399582204STAT3c.1954G>T (p.Glu652Ter)
c.*346G>T (n.*346G>T)
c.1927G>T (p.Glu643Ter)
n.1407G>T
c.*342G>T (n.*342G>T)
c.2050G>T (p.Glu684Ter)
n.2154G>T
c.1933G>T (p.Glu645Ter)
c.1870G>T (p.Glu624Ter)
c.1969G>T (p.Glu657Ter)
n.2391G>T
c.1858G>T (p.Glu620Ter)
n.2371G>T
n.2197G>T
c.1660G>T (p.Glu554Ter)
c.1876G>T (p.Glu626Ter)
c.1894G>T (p.Glu632Ter)
 dbSNP
17g.42322429C=CA2260430740STAT3c.1954G= (p.Glu652=)
c.*346G= (n.*346G=)
c.1927G= (p.Glu643=)
n.1407G=
c.*342G= (n.*342G=)
c.2050G= (p.Glu684=)
n.2154G=
c.1933G= (p.Glu645=)
c.1870G= (p.Glu624=)
c.1969G= (p.Glu657=)
n.2391G=
c.1858G= (p.Glu620=)
n.2371G=
n.2197G=
c.1660G= (p.Glu554=)
c.1876G= (p.Glu626=)
c.1894G= (p.Glu632=)
17g.42322429C>GCA399582207STAT3c.1954G>C (p.Glu652Gln)
c.*346G>C (n.*346G>C)
c.1927G>C (p.Glu643Gln)
n.1407G>C
c.*342G>C (n.*342G>C)
c.2050G>C (p.Glu684Gln)
n.2154G>C
c.1933G>C (p.Glu645Gln)
c.1870G>C (p.Glu624Gln)
c.1969G>C (p.Glu657Gln)
n.2391G>C
c.1858G>C (p.Glu620Gln)
n.2371G>C
n.2197G>C
c.1660G>C (p.Glu554Gln)
c.1876G>C (p.Glu626Gln)
c.1894G>C (p.Glu632Gln)
 dbSNP
17g.42322429C>TCA399582201STAT3c.1954G>A (p.Glu652Lys)
c.*346G>A (n.*346G>A)
c.1927G>A (p.Glu643Lys)
n.1407G>A
c.*342G>A (n.*342G>A)
c.2050G>A (p.Glu684Lys)
n.2154G>A
c.1933G>A (p.Glu645Lys)
c.1870G>A (p.Glu624Lys)
c.1969G>A (p.Glu657Lys)
n.2391G>A
c.1858G>A (p.Glu620Lys)
n.2371G>A
n.2197G>A
c.1660G>A (p.Glu554Lys)
c.1876G>A (p.Glu626Lys)
c.1894G>A (p.Glu632Lys)
 dbSNP COSMIC
17g.42322430A>CCA500061090STAT3c.1953T>G (p.Ala651=)
c.*345T>G (n.*345T>G)
c.1926T>G (p.Ala642=)
n.1406T>G
c.*341T>G (n.*341T>G)
c.2049T>G (p.Ala683=)
n.2153T>G
c.1932T>G (p.Ala644=)
c.1869T>G (p.Ala623=)
c.1968T>G (p.Ala656=)
n.2390T>G
c.1857T>G (p.Ala619=)
n.2370T>G
n.2196T>G
c.1659T>G (p.Ala553=)
c.1875T>G (p.Ala625=)
c.1893T>G (p.Ala631=)
17g.42322430A>GCA500061092STAT3c.1953T>C (p.Ala651=)
c.*345T>C (n.*345T>C)
c.1926T>C (p.Ala642=)
n.1406T>C
c.*341T>C (n.*341T>C)
c.2049T>C (p.Ala683=)
n.2153T>C
c.1932T>C (p.Ala644=)
c.1869T>C (p.Ala623=)
c.1968T>C (p.Ala656=)
n.2390T>C
c.1857T>C (p.Ala619=)
n.2370T>C
n.2196T>C
c.1659T>C (p.Ala553=)
c.1875T>C (p.Ala625=)
c.1893T>C (p.Ala631=)
 dbSNP COSMIC
17g.42322430A>TCA500061091STAT3c.1953T>A (p.Ala651=)
c.*345T>A (n.*345T>A)
c.1926T>A (p.Ala642=)
n.1406T>A
c.*341T>A (n.*341T>A)
c.2049T>A (p.Ala683=)
n.2153T>A
c.1932T>A (p.Ala644=)
c.1869T>A (p.Ala623=)
c.1968T>A (p.Ala656=)
n.2390T>A
c.1857T>A (p.Ala619=)
n.2370T>A
n.2196T>A
c.1659T>A (p.Ala553=)
c.1875T>A (p.Ala625=)
c.1893T>A (p.Ala631=)
 dbSNP
17g.42322431G>ACA399582216STAT3c.1952C>T (p.Ala651Val)
c.*344C>T (n.*344C>T)
c.1925C>T (p.Ala642Val)
n.1405C>T
c.*340C>T (n.*340C>T)
c.2048C>T (p.Ala683Val)
n.2152C>T
c.1931C>T (p.Ala644Val)
c.1868C>T (p.Ala623Val)
c.1967C>T (p.Ala656Val)
n.2389C>T
c.1856C>T (p.Ala619Val)
n.2369C>T
n.2195C>T
c.1658C>T (p.Ala553Val)
c.1874C>T (p.Ala625Val)
c.1892C>T (p.Ala631Val)
 dbSNP
17g.42322431G>CCA399582217STAT3c.1952C>G (p.Ala651Gly)
c.*344C>G (n.*344C>G)
c.1925C>G (p.Ala642Gly)
n.1405C>G
c.*340C>G (n.*340C>G)
c.2048C>G (p.Ala683Gly)
n.2152C>G
c.1931C>G (p.Ala644Gly)
c.1868C>G (p.Ala623Gly)
c.1967C>G (p.Ala656Gly)
n.2389C>G
c.1856C>G (p.Ala619Gly)
n.2369C>G
n.2195C>G
c.1658C>G (p.Ala553Gly)
c.1874C>G (p.Ala625Gly)
c.1892C>G (p.Ala631Gly)
 dbSNP gnomAD v4
17g.42322431G>TCA399582218STAT3c.1952C>A (p.Ala651Asp)
c.*344C>A (n.*344C>A)
c.1925C>A (p.Ala642Asp)
n.1405C>A
c.*340C>A (n.*340C>A)
c.2048C>A (p.Ala683Asp)
n.2152C>A
c.1931C>A (p.Ala644Asp)
c.1868C>A (p.Ala623Asp)
c.1967C>A (p.Ala656Asp)
n.2389C>A
c.1856C>A (p.Ala619Asp)
n.2369C>A
n.2195C>A
c.1658C>A (p.Ala553Asp)
c.1874C>A (p.Ala625Asp)
c.1892C>A (p.Ala631Asp)
 dbSNP
17g.42322432C>ACA399582219STAT3c.1951G>T (p.Ala651Ser)
c.*343G>T (n.*343G>T)
c.1924G>T (p.Ala642Ser)
n.1404G>T
c.*339G>T (n.*339G>T)
c.2047G>T (p.Ala683Ser)
n.2151G>T
c.1930G>T (p.Ala644Ser)
c.1867G>T (p.Ala623Ser)
c.1966G>T (p.Ala656Ser)
n.2388G>T
c.1855G>T (p.Ala619Ser)
n.2368G>T
n.2194G>T
c.1657G>T (p.Ala553Ser)
c.1873G>T (p.Ala625Ser)
c.1891G>T (p.Ala631Ser)
17g.42322432C>GCA399582221STAT3c.1951G>C (p.Ala651Pro)
c.*343G>C (n.*343G>C)
c.1924G>C (p.Ala642Pro)
n.1404G>C
c.*339G>C (n.*339G>C)
c.2047G>C (p.Ala683Pro)
n.2151G>C
c.1930G>C (p.Ala644Pro)
c.1867G>C (p.Ala623Pro)
c.1966G>C (p.Ala656Pro)
n.2388G>C
c.1855G>C (p.Ala619Pro)
n.2368G>C
n.2194G>C
c.1657G>C (p.Ala553Pro)
c.1873G>C (p.Ala625Pro)
c.1891G>C (p.Ala631Pro)
17g.42322432C>TCA399582223STAT3c.1951G>A (p.Ala651Thr)
c.*343G>A (n.*343G>A)
c.1924G>A (p.Ala642Thr)
n.1404G>A
c.*339G>A (n.*339G>A)
c.2047G>A (p.Ala683Thr)
n.2151G>A
c.1930G>A (p.Ala644Thr)
c.1867G>A (p.Ala623Thr)
c.1966G>A (p.Ala656Thr)
n.2388G>A
c.1855G>A (p.Ala619Thr)
n.2368G>A
n.2194G>A
c.1657G>A (p.Ala553Thr)
c.1873G>A (p.Ala625Thr)
c.1891G>A (p.Ala631Thr)
17g.42322433A>CCA399582224STAT3c.1950T>G (p.Phe650Leu)
c.*342T>G (n.*342T>G)
c.1923T>G (p.Phe641Leu)
n.1403T>G
c.*338T>G (n.*338T>G)
c.2046T>G (p.Phe682Leu)
n.2150T>G
c.1929T>G (p.Phe643Leu)
c.1866T>G (p.Phe622Leu)
c.1965T>G (p.Phe655Leu)
n.2387T>G
c.1854T>G (p.Phe618Leu)
n.2367T>G
n.2193T>G
c.1656T>G (p.Phe552Leu)
c.1872T>G (p.Phe624Leu)
c.1890T>G (p.Phe630Leu)
17g.42322433A>GCA500061093STAT3c.1950T>C (p.Phe650=)
c.*342T>C (n.*342T>C)
c.1923T>C (p.Phe641=)
n.1403T>C
c.*338T>C (n.*338T>C)
c.2046T>C (p.Phe682=)
n.2150T>C
c.1929T>C (p.Phe643=)
c.1866T>C (p.Phe622=)
c.1965T>C (p.Phe655=)
n.2387T>C
c.1854T>C (p.Phe618=)
n.2367T>C
n.2193T>C
c.1656T>C (p.Phe552=)
c.1872T>C (p.Phe624=)
c.1890T>C (p.Phe630=)
17g.42322433A>TCA399582225STAT3c.1950T>A (p.Phe650Leu)
c.*342T>A (n.*342T>A)
c.1923T>A (p.Phe641Leu)
n.1403T>A
c.*338T>A (n.*338T>A)
c.2046T>A (p.Phe682Leu)
n.2150T>A
c.1929T>A (p.Phe643Leu)
c.1866T>A (p.Phe622Leu)
c.1965T>A (p.Phe655Leu)
n.2387T>A
c.1854T>A (p.Phe618Leu)
n.2367T>A
n.2193T>A
c.1656T>A (p.Phe552Leu)
c.1872T>A (p.Phe624Leu)
c.1890T>A (p.Phe630Leu)
17g.42322434A>CCA399582228STAT3c.1949T>G (p.Phe650Cys)
c.*341T>G (n.*341T>G)
c.1922T>G (p.Phe641Cys)
n.1402T>G
c.*337T>G (n.*337T>G)
c.2045T>G (p.Phe682Cys)
n.2149T>G
c.1928T>G (p.Phe643Cys)
c.1865T>G (p.Phe622Cys)
c.1964T>G (p.Phe655Cys)
n.2386T>G
c.1853T>G (p.Phe618Cys)
n.2366T>G
n.2192T>G
c.1655T>G (p.Phe552Cys)
c.1871T>G (p.Phe624Cys)
c.1889T>G (p.Phe630Cys)
17g.42322434A>GCA399582230STAT3c.1949T>C (p.Phe650Ser)
c.*341T>C (n.*341T>C)
c.1922T>C (p.Phe641Ser)
n.1402T>C
c.*337T>C (n.*337T>C)
c.2045T>C (p.Phe682Ser)
n.2149T>C
c.1928T>C (p.Phe643Ser)
c.1865T>C (p.Phe622Ser)
c.1964T>C (p.Phe655Ser)
n.2386T>C
c.1853T>C (p.Phe618Ser)
n.2366T>C
n.2192T>C
c.1655T>C (p.Phe552Ser)
c.1871T>C (p.Phe624Ser)
c.1889T>C (p.Phe630Ser)
17g.42322434A>TCA399582234STAT3c.1949T>A (p.Phe650Tyr)
c.*341T>A (n.*341T>A)
c.1922T>A (p.Phe641Tyr)
n.1402T>A
c.*337T>A (n.*337T>A)
c.2045T>A (p.Phe682Tyr)
n.2149T>A
c.1928T>A (p.Phe643Tyr)
c.1865T>A (p.Phe622Tyr)
c.1964T>A (p.Phe655Tyr)
n.2386T>A
c.1853T>A (p.Phe618Tyr)
n.2366T>A
n.2192T>A
c.1655T>A (p.Phe552Tyr)
c.1871T>A (p.Phe624Tyr)
c.1889T>A (p.Phe630Tyr)
 dbSNP
17g.42322435A>CCA399582236STAT3c.1948T>G (p.Phe650Val)
c.*340T>G (n.*340T>G)
c.1921T>G (p.Phe641Val)
n.1401T>G
c.*336T>G (n.*336T>G)
c.2044T>G (p.Phe682Val)
n.2148T>G
c.1927T>G (p.Phe643Val)
c.1864T>G (p.Phe622Val)
c.1963T>G (p.Phe655Val)
n.2385T>G
c.1852T>G (p.Phe618Val)
n.2365T>G
n.2191T>G
c.1654T>G (p.Phe552Val)
c.1870T>G (p.Phe624Val)
c.1888T>G (p.Phe630Val)
 dbSNP
17g.42322435A>GCA399582238STAT3c.1948T>C (p.Phe650Leu)
c.*340T>C (n.*340T>C)
c.1921T>C (p.Phe641Leu)
n.1401T>C
c.*336T>C (n.*336T>C)
c.2044T>C (p.Phe682Leu)
n.2148T>C
c.1927T>C (p.Phe643Leu)
c.1864T>C (p.Phe622Leu)
c.1963T>C (p.Phe655Leu)
n.2385T>C
c.1852T>C (p.Phe618Leu)
n.2365T>C
n.2191T>C
c.1654T>C (p.Phe552Leu)
c.1870T>C (p.Phe624Leu)
c.1888T>C (p.Phe630Leu)
17g.42322435A>TCA399582242STAT3c.1948T>A (p.Phe650Ile)
c.*340T>A (n.*340T>A)
c.1921T>A (p.Phe641Ile)
n.1401T>A
c.*336T>A (n.*336T>A)
c.2044T>A (p.Phe682Ile)
n.2148T>A
c.1927T>A (p.Phe643Ile)
c.1864T>A (p.Phe622Ile)
c.1963T>A (p.Phe655Ile)
n.2385T>A
c.1852T>A (p.Phe618Ile)
n.2365T>A
n.2191T>A
c.1654T>A (p.Phe552Ile)
c.1870T>A (p.Phe624Ile)
c.1888T>A (p.Phe630Ile)
 dbSNP
17g.42322436T>ACA500061096STAT3c.1947A>T (p.Ser649=)
c.*339A>T (n.*339A>T)
c.1920A>T (p.Ser640=)
n.1400A>T
c.*335A>T (n.*335A>T)
c.2043A>T (p.Ser681=)
n.2147A>T
c.1926A>T (p.Ser642=)
c.1863A>T (p.Ser621=)
c.1962A>T (p.Ser654=)
n.2384A>T
c.1851A>T (p.Ser617=)
n.2364A>T
n.2190A>T
c.1653A>T (p.Ser551=)
c.1869A>T (p.Ser623=)
c.1887A>T (p.Ser629=)
 dbSNP gnomAD v3 gnomAD v4
17g.42322436T>CCA500061094STAT3c.1947A>G (p.Ser649=)
c.*339A>G (n.*339A>G)
c.1920A>G (p.Ser640=)
n.1400A>G
c.*335A>G (n.*335A>G)
c.2043A>G (p.Ser681=)
n.2147A>G
c.1926A>G (p.Ser642=)
c.1863A>G (p.Ser621=)
c.1962A>G (p.Ser654=)
n.2384A>G
c.1851A>G (p.Ser617=)
n.2364A>G
n.2190A>G
c.1653A>G (p.Ser551=)
c.1869A>G (p.Ser623=)
c.1887A>G (p.Ser629=)
 dbSNP
17g.42322436T>GCA500061095STAT3c.1947A>C (p.Ser649=)
c.*339A>C (n.*339A>C)
c.1920A>C (p.Ser640=)
n.1400A>C
c.*335A>C (n.*335A>C)
c.2043A>C (p.Ser681=)
n.2147A>C
c.1926A>C (p.Ser642=)
c.1863A>C (p.Ser621=)
c.1962A>C (p.Ser654=)
n.2384A>C
c.1851A>C (p.Ser617=)
n.2364A>C
n.2190A>C
c.1653A>C (p.Ser551=)
c.1869A>C (p.Ser623=)
c.1887A>C (p.Ser629=)
 dbSNP
17g.42322436T=CA2260430741STAT3c.1947A= (p.Ser649=)
c.*339A= (n.*339A=)
c.1920A= (p.Ser640=)
n.1400A=
c.*335A= (n.*335A=)
c.2043A= (p.Ser681=)
n.2147A=
c.1926A= (p.Ser642=)
c.1863A= (p.Ser621=)
c.1962A= (p.Ser654=)
n.2384A=
c.1851A= (p.Ser617=)
n.2364A=
n.2190A=
c.1653A= (p.Ser551=)
c.1869A= (p.Ser623=)
c.1887A= (p.Ser629=)
17g.42322437G>ACA399582250STAT3c.1946C>T (p.Ser649Leu)
c.*338C>T (n.*338C>T)
c.1919C>T (p.Ser640Leu)
n.1399C>T
c.*334C>T (n.*334C>T)
c.2042C>T (p.Ser681Leu)
n.2146C>T
c.1925C>T (p.Ser642Leu)
c.1862C>T (p.Ser621Leu)
c.1961C>T (p.Ser654Leu)
n.2383C>T
c.1850C>T (p.Ser617Leu)
n.2363C>T
n.2189C>T
c.1652C>T (p.Ser551Leu)
c.1868C>T (p.Ser623Leu)
c.1886C>T (p.Ser629Leu)
 dbSNP COSMIC
17g.42322437G>CCA399582252STAT3c.1946C>G (p.Ser649Ter)
c.*338C>G (n.*338C>G)
c.1919C>G (p.Ser640Ter)
n.1399C>G
c.*334C>G (n.*334C>G)
c.2042C>G (p.Ser681Ter)
n.2146C>G
c.1925C>G (p.Ser642Ter)
c.1862C>G (p.Ser621Ter)
c.1961C>G (p.Ser654Ter)
n.2383C>G
c.1850C>G (p.Ser617Ter)
n.2363C>G
n.2189C>G
c.1652C>G (p.Ser551Ter)
c.1868C>G (p.Ser623Ter)
c.1886C>G (p.Ser629Ter)
 dbSNP COSMIC
17g.42322437G>TCA399582247STAT3c.1946C>A (p.Ser649Ter)
c.*338C>A (n.*338C>A)
c.1919C>A (p.Ser640Ter)
n.1399C>A
c.*334C>A (n.*334C>A)
c.2042C>A (p.Ser681Ter)
n.2146C>A
c.1925C>A (p.Ser642Ter)
c.1862C>A (p.Ser621Ter)
c.1961C>A (p.Ser654Ter)
n.2383C>A
c.1850C>A (p.Ser617Ter)
n.2363C>A
n.2189C>A
c.1652C>A (p.Ser551Ter)
c.1868C>A (p.Ser623Ter)
c.1886C>A (p.Ser629Ter)
17g.42322438A>CCA399582262STAT3c.1945T>G (p.Ser649Ala)
c.*337T>G (n.*337T>G)
c.1918T>G (p.Ser640Ala)
n.1398T>G
c.*333T>G (n.*333T>G)
c.2041T>G (p.Ser681Ala)
n.2145T>G
c.1924T>G (p.Ser642Ala)
c.1861T>G (p.Ser621Ala)
c.1960T>G (p.Ser654Ala)
n.2382T>G
c.1849T>G (p.Ser617Ala)
n.2362T>G
n.2188T>G
c.1651T>G (p.Ser551Ala)
c.1867T>G (p.Ser623Ala)
c.1885T>G (p.Ser629Ala)
 dbSNP
17g.42322438A>GCA399582256STAT3c.1945T>C (p.Ser649Pro)
c.*337T>C (n.*337T>C)
c.1918T>C (p.Ser640Pro)
n.1398T>C
c.*333T>C (n.*333T>C)
c.2041T>C (p.Ser681Pro)
n.2145T>C
c.1924T>C (p.Ser642Pro)
c.1861T>C (p.Ser621Pro)
c.1960T>C (p.Ser654Pro)
n.2382T>C
c.1849T>C (p.Ser617Pro)
n.2362T>C
n.2188T>C
c.1651T>C (p.Ser551Pro)
c.1867T>C (p.Ser623Pro)
c.1885T>C (p.Ser629Pro)
 ClinVar dbSNP
17g.42322438A>TCA399582258STAT3c.1945T>A (p.Ser649Thr)
c.*337T>A (n.*337T>A)
c.1918T>A (p.Ser640Thr)
n.1398T>A
c.*333T>A (n.*333T>A)
c.2041T>A (p.Ser681Thr)
n.2145T>A
c.1924T>A (p.Ser642Thr)
c.1861T>A (p.Ser621Thr)
c.1960T>A (p.Ser654Thr)
n.2382T>A
c.1849T>A (p.Ser617Thr)
n.2362T>A
n.2188T>A
c.1651T>A (p.Ser551Thr)
c.1867T>A (p.Ser623Thr)
c.1885T>A (p.Ser629Thr)
 dbSNP
17g.42322439C>ACA399582267STAT3c.1944G>T (p.Met648Ile)
c.*336G>T (n.*336G>T)
c.1917G>T (p.Met639Ile)
n.1397G>T
c.*332G>T (n.*332G>T)
c.2040G>T (p.Met680Ile)
n.2144G>T
c.1923G>T (p.Met641Ile)
c.1860G>T (p.Met620Ile)
c.1959G>T (p.Met653Ile)
n.2381G>T
c.1848G>T (p.Met616Ile)
n.2361G>T
n.2187G>T
c.1650G>T (p.Met550Ile)
c.1866G>T (p.Met622Ile)
c.1884G>T (p.Met628Ile)
 dbSNP
17g.42322439C>GCA399582270STAT3c.1944G>C (p.Met648Ile)
c.*336G>C (n.*336G>C)
c.1917G>C (p.Met639Ile)
n.1397G>C
c.*332G>C (n.*332G>C)
c.2040G>C (p.Met680Ile)
n.2144G>C
c.1923G>C (p.Met641Ile)
c.1860G>C (p.Met620Ile)
c.1959G>C (p.Met653Ile)
n.2381G>C
c.1848G>C (p.Met616Ile)
n.2361G>C
n.2187G>C
c.1650G>C (p.Met550Ile)
c.1866G>C (p.Met622Ile)
c.1884G>C (p.Met628Ile)
 dbSNP
17g.42322439C>TCA399582274STAT3c.1944G>A (p.Met648Ile)
c.*336G>A (n.*336G>A)
c.1917G>A (p.Met639Ile)
n.1397G>A
c.*332G>A (n.*332G>A)
c.2040G>A (p.Met680Ile)
n.2144G>A
c.1923G>A (p.Met641Ile)
c.1860G>A (p.Met620Ile)
c.1959G>A (p.Met653Ile)
n.2381G>A
c.1848G>A (p.Met616Ile)
n.2361G>A
n.2187G>A
c.1650G>A (p.Met550Ile)
c.1866G>A (p.Met622Ile)
c.1884G>A (p.Met628Ile)
17g.42322440A=CA2260430742STAT3c.1943T= (p.Met648=)
c.*335T= (n.*335T=)
c.1916T= (p.Met639=)
n.1396T=
c.*331T= (n.*331T=)
c.2039T= (p.Met680=)
n.2143T=
c.1922T= (p.Met641=)
c.1859T= (p.Met620=)
c.1958T= (p.Met653=)
n.2380T=
c.1847T= (p.Met616=)
n.2360T=
n.2186T=
c.1649T= (p.Met550=)
c.1865T= (p.Met622=)
c.1883T= (p.Met628=)
17g.42322440A>CCA399582279STAT3c.1943T>G (p.Met648Arg)
c.*335T>G (n.*335T>G)
c.1916T>G (p.Met639Arg)
n.1396T>G
c.*331T>G (n.*331T>G)
c.2039T>G (p.Met680Arg)
n.2143T>G
c.1922T>G (p.Met641Arg)
c.1859T>G (p.Met620Arg)
c.1958T>G (p.Met653Arg)
n.2380T>G
c.1847T>G (p.Met616Arg)
n.2360T>G
n.2186T>G
c.1649T>G (p.Met550Arg)
c.1865T>G (p.Met622Arg)
c.1883T>G (p.Met628Arg)
17g.42322440A>GCA399582284STAT3c.1943T>C (p.Met648Thr)
c.*335T>C (n.*335T>C)
c.1916T>C (p.Met639Thr)
n.1396T>C
c.*331T>C (n.*331T>C)
c.2039T>C (p.Met680Thr)
n.2143T>C
c.1922T>C (p.Met641Thr)
c.1859T>C (p.Met620Thr)
c.1958T>C (p.Met653Thr)
n.2380T>C
c.1847T>C (p.Met616Thr)
n.2360T>C
n.2186T>C
c.1649T>C (p.Met550Thr)
c.1865T>C (p.Met622Thr)
c.1883T>C (p.Met628Thr)
 ClinVar
17g.42322440A>TCA16620410STAT3c.1943T>A (p.Met648Lys)
c.*335T>A (n.*335T>A)
c.1916T>A (p.Met639Lys)
n.1396T>A
c.*331T>A (n.*331T>A)
c.2039T>A (p.Met680Lys)
n.2143T>A
c.1922T>A (p.Met641Lys)
c.1859T>A (p.Met620Lys)
c.1958T>A (p.Met653Lys)
n.2380T>A
c.1847T>A (p.Met616Lys)
n.2360T>A
n.2186T>A
c.1649T>A (p.Met550Lys)
c.1865T>A (p.Met622Lys)
c.1883T>A (p.Met628Lys)
 ClinVar dbSNP
17g.42322441T>ACA399582289STAT3c.1942A>T (p.Met648Leu)
c.*334A>T (n.*334A>T)
c.1915A>T (p.Met639Leu)
n.1395A>T
c.*330A>T (n.*330A>T)
c.2038A>T (p.Met680Leu)
n.2142A>T
c.1921A>T (p.Met641Leu)
c.1858A>T (p.Met620Leu)
c.1957A>T (p.Met653Leu)
n.2379A>T
c.1846A>T (p.Met616Leu)
n.2359A>T
n.2185A>T
c.1648A>T (p.Met550Leu)
c.1864A>T (p.Met622Leu)
c.1882A>T (p.Met628Leu)
 dbSNP
17g.42322441T>CCA399582307STAT3c.1942A>G (p.Met648Val)
c.*334A>G (n.*334A>G)
c.1915A>G (p.Met639Val)
n.1395A>G
c.*330A>G (n.*330A>G)
c.2038A>G (p.Met680Val)
n.2142A>G
c.1921A>G (p.Met641Val)
c.1858A>G (p.Met620Val)
c.1957A>G (p.Met653Val)
n.2379A>G
c.1846A>G (p.Met616Val)
n.2359A>G
n.2185A>G
c.1648A>G (p.Met550Val)
c.1864A>G (p.Met622Val)
c.1882A>G (p.Met628Val)
 dbSNP
17g.42322441T>GCA399582310STAT3c.1942A>C (p.Met648Leu)
c.*334A>C (n.*334A>C)
c.1915A>C (p.Met639Leu)
n.1395A>C
c.*330A>C (n.*330A>C)
c.2038A>C (p.Met680Leu)
n.2142A>C
c.1921A>C (p.Met641Leu)
c.1858A>C (p.Met620Leu)
c.1957A>C (p.Met653Leu)
n.2379A>C
c.1846A>C (p.Met616Leu)
n.2359A>C
n.2185A>C
c.1648A>C (p.Met550Leu)
c.1864A>C (p.Met622Leu)
c.1882A>C (p.Met628Leu)

Number of alleles fetched