Canonical Allele Identifier: CA378532810

Gene: TCF7L2

Linked Data

• dbSNP Id: rs2135617475
• gnomAD v3: 10-113089503-A-T
• gnomAD v4: 10-113089503-A-T
• MyVariant Identifiers: chr10:g.114849262A>T (hg19) ; chr10:g.113089503A>T (hg38)

Genomic Alleles

HGVS	Genome Assembly
NC_000010.11:g.113089503A>T , CM000672.2:g.113089503A>T	GRCh38
NC_000010.10:g.114849262A>T , CM000672.1:g.114849262A>T	GRCh37
NC_000010.9:g.114839252A>T	NCBI36
NG_012631.1:g.144254A>T

Transcript Alleles

HGVS	Amino-acid Change
ENST00000277945.12:c.483+49377A>T	ENSP00000277945.8:n.483+49377A>T
ENST00000355995.9:c.552+49377A>T MANE Select	ENSP00000348274.4:n.552+49377A>T
ENST00000704414.1:c.483+49377A>T	ENSP00000515891.1:n.483+49377A>T
ENST00000352065.10:c.483+49377A>T	ENSP00000344823.5:n.483+49377A>T
ENST00000355717.9:c.587A>T	ENSP00000347949.4:p.His196Leu
ENST00000369395.6:c.483+49377A>T	ENSP00000358402.2:n.483+49377A>T
ENST00000545257.6:c.483+49377A>T	ENSP00000440547.2:n.483+49377A>T
ENST00000627217.3:c.552+49377A>T	ENSP00000486891.1:n.552+49377A>T
ENST00000346198.5:c.497A>T	ENSP00000345640.4:p.His166Leu
ENST00000349937.6:c.552+49377A>T	ENSP00000298692.4:n.552+49377A>T
ENST00000352065.9:c.483+49377A>T	ENSP00000344823.5:n.483+49377A>T
ENST00000355717.8:c.587A>T	ENSP00000347949.4:p.His196Leu
ENST00000355995.8:c.552+49377A>T	ENSP00000348274.4:n.552+49377A>T
ENST00000369395.5:c.590A>T	ENSP00000358402.1:p.His197Leu
ENST00000369397.8:c.483+49377A>T	ENSP00000358404.4:n.483+49377A>T
ENST00000534894.5:c.382-51681A>T	ENSP00000443626.2:n.382-51681A>T
ENST00000536810.5:c.483+49377A>T	ENSP00000446238.2:n.483+49377A>T
ENST00000538897.5:c.552+49377A>T	ENSP00000446172.1:n.552+49377A>T
ENST00000542695.5:c.272A>T	ENSP00000443883.2:p.His91Leu
ENST00000543371.5:c.552+49377A>T	ENSP00000444972.2:n.552+49377A>T
ENST00000545257.5:c.483+49377A>T	ENSP00000440547.2:n.483+49377A>T
ENST00000627217.2:c.552+49377A>T	ENSP00000486891.1:n.552+49377A>T
ENST00000629706.2:c.483+49377A>T	ENSP00000487507.1:n.483+49377A>T
NM_001146274.1:c.552+49377A>T	NP_001139746.1:n.552+49377A>T
NM_001146283.1:c.587A>T	NP_001139755.1:p.His196Leu
NM_001146284.1:c.483+49377A>T	NP_001139756.1:n.483+49377A>T
NM_001146285.1:c.483+49377A>T	NP_001139757.1:n.483+49377A>T
NM_001146286.1:c.483+49377A>T	NP_001139758.1:n.483+49377A>T
NM_001198525.1:c.483+49377A>T	NP_001185454.1:n.483+49377A>T
NM_001198526.1:c.483+49377A>T	NP_001185455.1:n.483+49377A>T
NM_001198527.1:c.483+49377A>T	NP_001185456.1:n.483+49377A>T
NM_001198528.1:c.483+49377A>T	NP_001185457.1:n.483+49377A>T
NM_001198529.1:c.483+49377A>T	NP_001185458.1:n.483+49377A>T
NM_001198530.1:c.382-51681A>T	NP_001185459.1:n.382-51681A>T
NM_001198531.1:c.552+49377A>T	NP_001185460.1:n.552+49377A>T
NM_030756.4:c.483+49377A>T	NP_110383.2:n.483+49377A>T
XM_005270071.1:c.659A>T	XP_005270128.1:p.His220Leu
XM_005270073.1:c.656A>T	XP_005270130.1:p.His219Leu
XM_005270074.1:c.659A>T	XP_005270131.1:p.His220Leu
XM_005270075.1:c.659A>T	XP_005270132.1:p.His220Leu
XM_005270077.1:c.659A>T	XP_005270134.1:p.His220Leu
XM_005270078.1:c.659A>T	XP_005270135.1:p.His220Leu
XM_005270079.1:c.659A>T	XP_005270136.1:p.His220Leu
XM_005270080.1:c.590A>T	XP_005270137.1:p.His197Leu
XM_005270082.1:c.552+49377A>T	XP_005270139.1:n.552+49377A>T
XM_005270083.1:c.552+49377A>T	XP_005270140.1:n.552+49377A>T
XM_005270084.1:c.552+49377A>T	XP_005270141.1:n.552+49377A>T
XM_005270085.1:c.552+49377A>T	XP_005270142.1:n.552+49377A>T
XM_005270086.1:c.483+49377A>T	XP_005270143.1:n.483+49377A>T
XM_005270088.1:c.483+49377A>T	XP_005270145.1:n.483+49377A>T
XM_005270089.1:c.483+49377A>T	XP_005270146.1:n.483+49377A>T
XM_005270091.2:c.659A>T	XP_005270148.1:p.His220Leu
XM_005270092.1:c.659A>T	XP_005270149.1:p.His220Leu
XM_005270093.1:c.659A>T	XP_005270150.1:p.His220Leu
XM_005270094.1:c.656A>T	XP_005270151.1:p.His219Leu
XM_005270095.1:c.659A>T	XP_005270152.1:p.His220Leu
XM_005270096.1:c.552+49377A>T	XP_005270153.1:n.552+49377A>T
XM_005270100.1:c.552+49377A>T	XP_005270157.1:n.552+49377A>T
XM_005270101.1:c.483+49377A>T	XP_005270158.1:n.483+49377A>T
XM_005270102.1:c.552+49377A>T	XP_005270159.1:n.552+49377A>T
XM_005270103.1:c.483+49377A>T	XP_005270160.1:n.483+49377A>T
XM_005270104.1:c.483+49377A>T	XP_005270161.1:n.483+49377A>T
XM_006717956.2:c.200A>T	XP_006718019.1:p.His67Leu
XM_011540109.1:c.659A>T	XP_011538411.1:p.His220Leu
XM_011540110.1:c.590A>T	XP_011538412.1:p.His197Leu
XM_011540111.1:c.483+49377A>T	XP_011538413.1:n.483+49377A>T
XM_011540112.1:c.659A>T	XP_011538414.1:p.His220Leu
XM_011540113.1:c.659A>T	XP_011538415.1:p.His220Leu
XM_011540114.1:c.659A>T	XP_011538416.1:p.His220Leu
XM_011540115.1:c.659A>T	XP_011538417.1:p.His220Leu
XM_011540116.1:c.659A>T	XP_011538418.1:p.His220Leu
XM_011540117.1:c.659A>T	XP_011538419.1:p.His220Leu
XM_011540118.1:c.659A>T	XP_011538420.1:p.His220Leu
XM_011540119.1:c.659A>T	XP_011538421.1:p.His220Leu
NM_001363501.1:c.552+49377A>T	NP_001350430.1:n.552+49377A>T
XM_005270071.2:c.659A>T	XP_005270128.1:p.His220Leu
XM_005270075.2:c.659A>T	XP_005270132.1:p.His220Leu
XM_005270077.2:c.659A>T	XP_005270134.1:p.His220Leu
XM_005270078.2:c.659A>T	XP_005270135.1:p.His220Leu
XM_005270079.2:c.659A>T	XP_005270136.1:p.His220Leu
XM_005270080.2:c.590A>T	XP_005270137.1:p.His197Leu
XM_005270084.2:c.552+49377A>T	XP_005270141.1:n.552+49377A>T
XM_005270085.2:c.552+49377A>T	XP_005270142.1:n.552+49377A>T
XM_005270086.2:c.483+49377A>T	XP_005270143.1:n.483+49377A>T
XM_005270088.2:c.483+49377A>T	XP_005270145.1:n.483+49377A>T
XM_005270089.2:c.483+49377A>T	XP_005270146.1:n.483+49377A>T
XM_005270091.3:c.659A>T	XP_005270148.1:p.His220Leu
XM_005270092.2:c.659A>T	XP_005270149.1:p.His220Leu
XM_005270093.3:c.659A>T	XP_005270150.1:p.His220Leu
XM_005270094.3:c.656A>T	XP_005270151.1:p.His219Leu
XM_005270095.2:c.659A>T	XP_005270152.1:p.His220Leu
XM_005270100.2:c.552+49377A>T	XP_005270157.1:n.552+49377A>T
XM_005270101.3:c.483+49377A>T	XP_005270158.1:n.483+49377A>T
XM_005270102.2:c.552+49377A>T	XP_005270159.1:n.552+49377A>T
XM_005270103.2:c.483+49377A>T	XP_005270160.1:n.483+49377A>T
XM_005270104.2:c.483+49377A>T	XP_005270161.1:n.483+49377A>T
XM_011540109.2:c.659A>T	XP_011538411.1:p.His220Leu
XM_011540110.2:c.590A>T	XP_011538412.1:p.His197Leu
XM_011540111.2:c.483+49377A>T	XP_011538413.1:n.483+49377A>T
XM_011540116.2:c.659A>T	XP_011538418.1:p.His220Leu
XM_017016584.2:c.656A>T	XP_016872073.1:p.His219Leu
XM_017016585.2:c.659A>T	XP_016872074.1:p.His220Leu
XM_017016586.2:c.659A>T	XP_016872075.1:p.His220Leu
XM_017016587.2:c.659A>T	XP_016872076.1:p.His220Leu
XM_017016588.2:c.590A>T	XP_016872077.1:p.His197Leu
XM_017016589.2:c.659A>T	XP_016872078.1:p.His220Leu
XM_017016590.2:c.552+49377A>T	XP_016872079.1:n.552+49377A>T
XM_017016591.2:c.552+49377A>T	XP_016872080.1:n.552+49377A>T
XM_017016592.2:c.552+49377A>T	XP_016872081.1:n.552+49377A>T
XM_017016593.2:c.552+49377A>T	XP_016872082.1:n.552+49377A>T
XM_017016594.2:c.483+49377A>T	XP_016872083.1:n.483+49377A>T
XM_017016595.2:c.659A>T	XP_016872084.1:p.His220Leu
XM_017016596.2:c.552+49377A>T	XP_016872085.1:n.552+49377A>T
XM_024448150.1:c.587A>T	XP_024303918.1:p.His196Leu
NM_001146274.2:c.552+49377A>T	NP_001139746.1:n.552+49377A>T
NM_001367943.1:c.552+49377A>T MANE Select	NP_001354872.1:n.552+49377A>T
NM_001146283.2:c.587A>T	NP_001139755.1:p.His196Leu
NM_001146284.2:c.483+49377A>T	NP_001139756.1:n.483+49377A>T
NM_001146286.2:c.483+49377A>T	NP_001139758.1:n.483+49377A>T
NM_001198525.2:c.483+49377A>T	NP_001185454.1:n.483+49377A>T
NM_001198526.2:c.483+49377A>T	NP_001185455.1:n.483+49377A>T
NM_001198527.2:c.483+49377A>T	NP_001185456.1:n.483+49377A>T
NM_001198528.2:c.483+49377A>T	NP_001185457.1:n.483+49377A>T
NM_001198529.2:c.483+49377A>T	NP_001185458.1:n.483+49377A>T
NM_001198531.2:c.552+49377A>T	NP_001185460.1:n.552+49377A>T
NM_030756.5:c.483+49377A>T	NP_110383.2:n.483+49377A>T
NM_001146285.2:c.483+49377A>T	NP_001139757.1:n.483+49377A>T
NM_001198530.2:c.382-51681A>T	NP_001185459.1:n.382-51681A>T
NM_001363501.2:c.552+49377A>T	NP_001350430.1:n.552+49377A>T