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      "hgvs": [
        "NM_001077490.3:c.1014G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_001070958.1:p.Pro338="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS711767"
    },
    {
      "coordinates": [
        {
          "allele": "A",
          "end": 1139,
          "endIntronDirection": "+",
          "endIntronOffset": 13580,
          "referenceAllele": "G",
          "start": 1139,
          "startIntronDirection": "+",
          "startIntronOffset": 13579
        }
      ],
      "gene": "http://reg.genome.network/gene/GN004392",
      "geneNCBI_id": 2778,
      "geneSymbol": "GNAS",
      "hgvs": [
        "NM_016592.5:c.*42+13580G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_057676.1:n.*42+13580G>A"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS728196",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Plus Clinical",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000371075.7:c.*42+13580G>A"
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          "RefSeq": {
            "hgvs": "NM_016592.5:c.*42+13580G>A"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000360115.3:n.*42+13580G>A"
          },
          "RefSeq": {
            "hgvs": "NP_057676.1:n.*42+13580G>A"
          }
        }
      }
    },
    {
      "@id": "http://reg.genome.network/allele/PA2830155859",
      "coordinates": [
        {
          "allele": "A",
          "end": 1751,
          "referenceAllele": "G",
          "start": 1750
        }
      ],
      "gene": "http://reg.genome.network/gene/GN004392",
      "geneNCBI_id": 2778,
      "geneSymbol": "GNAS",
      "hgvs": [
        "NM_080425.4:c.1201G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_536350.2:p.Asp401Asn",
        "hgvsWellDefined": "NP_536350.2:p.Asp401Asn"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS729035",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Plus Clinical",
        "nucleotide": {
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            "hgvs": "ENST00000371100.9:c.1201G>A"
          },
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        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000360141.3:p.Asp401Asn"
          },
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            "hgvs": "NP_536350.2:p.Asp401Asn"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}