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      ],
      "gene": "http://reg.genome.network/gene/GN009175",
      "geneNCBI_id": 5424,
      "geneSymbol": "POLD1",
      "hgvs": [
        "XM_005259008.4:c.3233del"
      ],
      "proteinEffect": {
        "hgvs": "XP_005259065.1:p.Pro1078LeufsTer22",
        "hgvsWellDefined": "XP_005259065.1:p.[Pro1077_Pro1078insLeuAspLeuArg;Pro1080_Glu1081delinsAspLeu;Ala1082_Trp1083insSerIlePro;Trp1083_Ter1084insGlyGlyGlyGlyThrArgGluAsn]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS534923"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3451,
          "referenceAllele": "C",
          "start": 3450
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      ],
      "gene": "http://reg.genome.network/gene/GN009175",
      "geneNCBI_id": 5424,
      "geneSymbol": "POLD1",
      "hgvs": [
        "XM_017026881.1:c.3305del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016882370.1:p.Pro1102LeufsTer22",
        "hgvsWellDefined": "XP_016882370.1:p.[Pro1101_Pro1102insLeuAspLeuArg;Pro1104_Glu1105delinsAspLeu;Ala1106_Trp1107insSerIlePro;Trp1107_Ter1108insGlyGlyGlyGlyThrArgGluAsn]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS576925"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3296,
          "referenceAllele": "C",
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      ],
      "gene": "http://reg.genome.network/gene/GN009175",
      "geneNCBI_id": 5424,
      "geneSymbol": "POLD1",
      "hgvs": [
        "XM_017026882.2:c.3233del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016882371.1:p.Pro1078LeufsTer22",
        "hgvsWellDefined": "XP_016882371.1:p.[Pro1077_Pro1078insLeuAspLeuArg;Pro1080_Glu1081delinsAspLeu;Ala1082_Trp1083insSerIlePro;Trp1083_Ter1084insGlyGlyGlyGlyThrArgGluAsn]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS576926"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3350,
          "referenceAllele": "C",
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      ],
      "gene": "http://reg.genome.network/gene/GN009175",
      "geneNCBI_id": 5424,
      "geneSymbol": "POLD1",
      "hgvs": [
        "NM_002691.4:c.3305del"
      ],
      "proteinEffect": {
        "hgvs": "NP_002682.2:p.Pro1102LeufsTer22",
        "hgvsWellDefined": "NP_002682.2:p.[Pro1101_Pro1102insLeuAspLeuArg;Pro1104_Glu1105delinsAspLeu;Ala1106_Trp1107insSerIlePro;Trp1107_Ter1108insGlyGlyGlyGlyThrArgGluAsn]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS695609",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000440232.7:c.3305del"
          },
          "RefSeq": {
            "hgvs": "NM_002691.4:c.3305del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000406046.1:p.Pro1102LeufsTer22"
          },
          "RefSeq": {
            "hgvs": "NP_002682.2:p.Pro1102LeufsTer22"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3247,
          "referenceAllele": "C",
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      ],
      "gene": "http://reg.genome.network/gene/GN009175",
      "geneNCBI_id": 5424,
      "geneSymbol": "POLD1",
      "hgvs": [
        "NR_046402.2:n.3247del"
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      "referenceSequence": "http://reg.genome.network/refseq/RS702488"
    }
  ],
  "type": "nucleotide"
}