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        "hgvs": "XP_011544248.1:p.Glu572ArgfsTer29",
        "hgvsWellDefined": "XP_011544248.1:p.[Glu572_Tyr582delinsArgIleProPheLeuGlyValIleVal;Ser584_Phe594delinsIleTyrProTrpMetMetMetLeuSerArgLeu;Arg596_Asp597delinsPheIle;Leu600_Ser601delinsGluCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556315"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 2677,
          "referenceAllele": "A",
          "start": 2676
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545947.2:c.1713del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544249.1:p.Glu572ArgfsTer29",
        "hgvsWellDefined": "XP_011544249.1:p.[Glu572_Tyr582delinsArgIleProPheLeuGlyValIleVal;Ser584_Phe594delinsIleTyrProTrpMetMetMetLeuSerArgLeu;Arg596_Asp597delinsPheIle;Leu600_Ser601delinsGluCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556316"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1999,
          "referenceAllele": "A",
          "start": 1998
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545948.2:c.822del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544250.1:p.Glu275ArgfsTer29",
        "hgvsWellDefined": "XP_011544250.1:p.[Glu275_Tyr285delinsArgIleProPheLeuGlyValIleVal;Ser287_Phe297delinsIleTyrProTrpMetMetMetLeuSerArgLeu;Arg299_Asp300delinsPheIle;Leu303_Ser304delinsGluCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556317"
    },
    {
      "coordinates": [
        {
          "allele": "",
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      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023671.1:c.1713del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879160.1:p.Glu572ArgfsTer29",
        "hgvsWellDefined": "XP_016879160.1:p.[Glu572_Tyr582delinsArgIleProPheLeuGlyValIleVal;Ser584_Phe594delinsIleTyrProTrpMetMetMetLeuSerArgLeu;Arg596_Asp597delinsPheIle;Leu600_Ser601delinsGluCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574393"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1887,
          "referenceAllele": "A",
          "start": 1886
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023672.2:c.1707del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879161.1:p.Glu570ArgfsTer29",
        "hgvsWellDefined": "XP_016879161.1:p.[Glu570_Tyr580delinsArgIleProPheLeuGlyValIleVal;Ser582_Phe592delinsIleTyrProTrpMetMetMetLeuSerArgLeu;Arg594_Asp595delinsPheIle;Leu598_Ser599delinsGluCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574394"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1887,
          "referenceAllele": "A",
          "start": 1886
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023673.2:c.1707del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879162.1:p.Glu570ArgfsTer29",
        "hgvsWellDefined": "XP_016879162.1:p.[Glu570_Tyr580delinsArgIleProPheLeuGlyValIleVal;Ser582_Phe592delinsIleTyrProTrpMetMetMetLeuSerArgLeu;Arg594_Asp595delinsPheIle;Leu598_Ser599delinsGluCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574395"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1860,
          "referenceAllele": "A",
          "start": 1859
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "NM_024675.4:c.1707del"
      ],
      "proteinEffect": {
        "hgvs": "NP_078951.2:p.Glu570ArgfsTer29",
        "hgvsWellDefined": "NP_078951.2:p.[Glu570_Tyr580delinsArgIleProPheLeuGlyValIleVal;Ser582_Phe592delinsIleTyrProTrpMetMetMetLeuSerArgLeu;Arg594_Asp595delinsPheIle;Leu598_Ser599delinsGluCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698739",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000261584.9:c.1707del"
          },
          "RefSeq": {
            "hgvs": "NM_024675.4:c.1707del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000261584.4:p.Glu570ArgfsTer29"
          },
          "RefSeq": {
            "hgvs": "NP_078951.2:p.Glu570ArgfsTer29"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}