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      "hgvs": [
        "NM_001369804.2:c.841dup"
      ],
      "proteinEffect": {
        "hgvs": "NP_001356733.1:p.His281ProfsTer?",
        "hgvsWellDefined": "NP_001356733.1:p.[His281_Leu287delinsProGlnCysGlyLeuProIle;Gly288_Leu289insSer;Phe290_Pro292delinsArgAlaArg;Asp294_Tyr297delinsHisAlaValArgAla;Leu299_Asn300delinsGlnGluGln;Asn302_Asn303delinsAspGlyPro;Asp306_Ser308del;Ser310del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS691986"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1073,
          "referenceAllele": "",
          "start": 1073
        }
      ],
      "gene": "http://reg.genome.network/gene/GN000438",
      "geneNCBI_id": 249,
      "geneSymbol": "ALPL",
      "hgvs": [
        "NM_001369805.2:c.841dup"
      ],
      "proteinEffect": {
        "hgvs": "NP_001356734.1:p.His281ProfsTer?",
        "hgvsWellDefined": "NP_001356734.1:p.[His281_Leu287delinsProGlnCysGlyLeuProIle;Gly288_Leu289insSer;Phe290_Pro292delinsArgAlaArg;Asp294_Tyr297delinsHisAlaValArgAla;Leu299_Asn300delinsGlnGluGln;Asn302_Asn303delinsAspGlyPro;Asp306_Ser308del;Ser310del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS691987"
    }
  ],
  "type": "nucleotide"
}