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      "hgvs": [
        "XM_017019774.1:c.2458+11G>A"
      ],
      "proteinEffect": {
        "hgvs": "XP_016875263.1:n.2458+11G>A"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS571368"
    },
    {
      "coordinates": [
        {
          "allele": "A",
          "end": 2538,
          "endIntronDirection": "+",
          "endIntronOffset": 11,
          "referenceAllele": "G",
          "start": 2538,
          "startIntronDirection": "+",
          "startIntronOffset": 10
        }
      ],
      "gene": "http://reg.genome.network/gene/GN018083",
      "geneNCBI_id": 59341,
      "geneSymbol": "TRPV4",
      "hgvs": [
        "NM_021625.5:c.2458+11G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_067638.3:n.2458+11G>A"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698429",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000261740.7:c.2458+11G>A"
          },
          "RefSeq": {
            "hgvs": "NM_021625.5:c.2458+11G>A"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000261740.2:n.2458+11G>A"
          },
          "RefSeq": {
            "hgvs": "NP_067638.3:n.2458+11G>A"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}