{
  "@context": "http://reg.genome.network/schema/allele.jsonld",
  "@id": "http://reg.genome.network/allele/CA614273519",
  "communityStandardTitle": [
    "NM_020937.4(FANCM):c.1397-16_1397-15del"
  ],
  "externalRecords": {
    "MyVariantInfo_hg19": [
      {
        "@id": "http://myvariant.info/v1/variant/chr14:g.45628280_45628281del?assembly=hg19",
        "id": "chr14:g.45628280_45628281del"
      }
    ],
    "dbSNP": [
      {
        "@id": "http://www.ncbi.nlm.nih.gov/snp/875989813",
        "rs": 875989813
      }
    ],
    "gnomAD_2": [
      {
        "@id": "http://gnomad.broadinstitute.org/variant/14-45628279-GTT-G?dataset=gnomad_r2_1",
        "id": "14-45628279-GTT-G",
        "variant": "14:45628279 GTT / G"
      }
    ],
    "gnomAD_4": [
      {
        "@id": "http://gnomad.broadinstitute.org/variant/14-45159076-GTT-G?dataset=gnomad_r4",
        "id": "14-45159076-GTT-G",
        "variant": "14:45159076 GTT / G"
      }
    ]
  },
  "genomicAlleles": [
    {
      "chromosome": "14",
      "coordinates": [
        {
          "allele": "",
          "end": 45159081,
          "referenceAllele": "TT",
          "start": 45159079
        }
      ],
      "hgvs": [
        "NC_000014.9:g.45159080_45159081del",
        "CM000676.2:g.45159080_45159081del"
      ],
      "referenceGenome": "GRCh38",
      "referenceSequence": "http://reg.genome.network/refseq/RS000062"
    },
    {
      "chromosome": "14",
      "coordinates": [
        {
          "allele": "",
          "end": 45628284,
          "referenceAllele": "TT",
          "start": 45628282
        }
      ],
      "hgvs": [
        "NC_000014.8:g.45628283_45628284del",
        "CM000676.1:g.45628283_45628284del"
      ],
      "referenceGenome": "GRCh37",
      "referenceSequence": "http://reg.genome.network/refseq/RS000038"
    },
    {
      "chromosome": "14",
      "coordinates": [
        {
          "allele": "",
          "end": 44698034,
          "referenceAllele": "TT",
          "start": 44698032
        }
      ],
      "hgvs": [
        "NC_000014.7:g.44698033_44698034del"
      ],
      "referenceGenome": "NCBI36",
      "referenceSequence": "http://reg.genome.network/refseq/RS000014"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 28149,
          "referenceAllele": "TT",
          "start": 28147
        }
      ],
      "hgvs": [
        "NG_007417.1:g.28148_28149del",
        "LRG_502:g.28148_28149del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS000573"
    }
  ],
  "transcriptAlleles": [
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1496,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1496,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000556036.6:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000450596.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS905872"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1498,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1498,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000556250.6:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000452033.2:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS905875"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1339,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1339,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696641.1:c.1238-16_1238-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512774.1:n.1238-16_1238-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908087"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1302,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1302,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696642.1:c.*208-16_*208-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512775.1:n.*208-16_*208-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908088"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1422,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1422,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696643.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512776.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908089"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1277,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1277,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696646.1:c.*208-16_*208-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512777.1:n.*208-16_*208-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908092"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1475,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1475,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696647.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512778.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908093"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1425,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1425,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696648.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512779.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908094"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1425,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1425,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696649.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512780.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908095"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1344,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1344,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696650.1:n.1345-16_1345-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908096"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1946,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1946,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696658.1:n.1947-16_1947-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908104"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1347,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1347,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696662.1:c.1319-16_1319-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512788.1:n.1319-16_1319-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908107"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 213,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 213,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696663.1:c.214-16_214-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908108"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 213,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 213,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696664.1:c.214-16_214-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908109"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1457,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1457,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696675.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512799.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908120"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1293,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1293,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696680.1:c.1265-16_1265-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512803.1:n.1265-16_1265-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908125"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1292,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1292,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696681.1:c.*208-16_*208-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512804.1:n.*208-16_*208-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908126"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1417,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1417,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696682.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000512805.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908127"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 213,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 213,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696683.1:c.214-16_214-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908128"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 213,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 213,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696684.1:c.214-16_214-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908129"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 213,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 213,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000696685.1:c.214-16_214-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908130"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1498,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1498,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000267430.10:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000267430.5:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS742993",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000267430.10:c.1397-16_1397-15del"
          },
          "RefSeq": {
            "hgvs": "NM_020937.4:c.1397-16_1397-15del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000267430.5:n.1397-16_1397-15del"
          },
          "RefSeq": {
            "hgvs": "NP_065988.1:n.1397-16_1397-15del"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1481,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1481,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000267430.9:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000267430.5:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS251992"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1396,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1396,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000542564.6:c.1319-16_1319-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000442493.2:n.1319-16_1319-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS363528"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000556036.5:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000450596.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS371909"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 151,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 151,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "ENST00000556250.5:c.152-16_152-15del"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000452033.1:n.152-16_152-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS372072"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1411,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1411,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "NM_001308133.1:c.1319-16_1319-15del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001295062.1:n.1319-16_1319-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS026161"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1489,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1489,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "NM_001308134.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001295063.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS026162"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1495,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1495,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "NM_020937.2:c.1397-16_1397-15del",
        "LRG_502t1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "NP_065988.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS036705"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1489,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1489,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "NM_020937.3:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "NP_065988.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS036706"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_011537034.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011535336.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS104004"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1410,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1410,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_011537035.1:c.1319-16_1319-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011535337.1:n.1319-16_1319-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS104005"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_011537036.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011535338.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS104006"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_011537034.2:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011535336.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS552724"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1410,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1410,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_011537035.3:c.1319-16_1319-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011535337.1:n.1319-16_1319-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS552725"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_017021523.1:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016877012.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS572701"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 710,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 710,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_017021524.2:c.434-16_434-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016877013.1:n.434-16_434-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS572702"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1277,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1277,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_017021525.2:c.212-16_212-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016877014.1:n.212-16_212-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS572703"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 521,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 521,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_017021526.2:c.212-16_212-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016877015.1:n.212-16_212-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS572704"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1302,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1302,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XM_017021527.1:c.212-16_212-15del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016877016.1:n.212-16_212-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS572705"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XR_001750470.1:n.1489-16_1489-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS597745"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XR_001750471.2:n.1489-16_1489-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS597746"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1488,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1488,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "XR_001750472.1:n.1489-16_1489-15del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS597747"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1498,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1498,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "NM_020937.4:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "NP_065988.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS670157",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000267430.10:c.1397-16_1397-15del"
          },
          "RefSeq": {
            "hgvs": "NM_020937.4:c.1397-16_1397-15del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000267430.5:n.1397-16_1397-15del"
          },
          "RefSeq": {
            "hgvs": "NP_065988.1:n.1397-16_1397-15del"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1420,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1420,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "NM_001308133.2:c.1319-16_1319-15del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001295062.1:n.1319-16_1319-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS683939"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1498,
          "endIntronDirection": "-",
          "endIntronOffset": 14,
          "referenceAllele": "TT",
          "start": 1498,
          "startIntronDirection": "-",
          "startIntronOffset": 16
        }
      ],
      "gene": "http://reg.genome.network/gene/GN023168",
      "geneNCBI_id": 57697,
      "geneSymbol": "FANCM",
      "hgvs": [
        "NM_001308134.2:c.1397-16_1397-15del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001295063.1:n.1397-16_1397-15del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS717231"
    }
  ],
  "type": "nucleotide"
}