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      "gene": "http://reg.genome.network/gene/GN002638",
      "geneNCBI_id": 1577,
      "geneSymbol": "CYP3A5",
      "hgvs": [
        "NM_001291829.2:c.-390C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001278758.1:n.-390C>T"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS682873"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 442,
          "referenceAllele": "C",
          "start": 441
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002638",
      "geneNCBI_id": 1577,
      "geneSymbol": "CYP3A5",
      "hgvs": [
        "NM_001291830.2:c.52C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001278759.1:p.Arg18Cys",
        "hgvsWellDefined": "NP_001278759.1:p.Arg18Cys"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS682874"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 550,
          "referenceAllele": "C",
          "start": 549
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002638",
      "geneNCBI_id": 1577,
      "geneSymbol": "CYP3A5",
      "hgvs": [
        "NR_033807.3:n.550C>T"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS702171"
    }
  ],
  "type": "nucleotide"
}