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          "referenceAllele": "T",
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      "gene": "http://reg.genome.network/gene/GN000620",
      "geneNCBI_id": 351,
      "geneSymbol": "APP",
      "hgvs": [
        "NM_201414.3:c.1846T>C"
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      "proteinEffect": {
        "hgvs": "NP_958817.1:p.Phe616Leu",
        "hgvsWellDefined": "NP_958817.1:p.Phe616Leu"
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      "referenceSequence": "http://reg.genome.network/refseq/RS701542"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1933,
          "referenceAllele": "T",
          "start": 1932
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      ],
      "gene": "http://reg.genome.network/gene/GN000620",
      "geneNCBI_id": 351,
      "geneSymbol": "APP",
      "hgvs": [
        "NM_001136131.3:c.1741T>C"
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      "proteinEffect": {
        "hgvs": "NP_001129603.1:p.Phe581Leu",
        "hgvsWellDefined": "NP_001129603.1:p.Phe581Leu"
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      "referenceSequence": "http://reg.genome.network/refseq/RS712494"
    },
    {
      "coordinates": [
        {
          "allele": "C",
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          "referenceAllele": "T",
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      "geneNCBI_id": 351,
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      "referenceSequence": "http://reg.genome.network/refseq/RS723592"
    }
  ],
  "type": "nucleotide"
}