{
  "@context": "http://reg.genome.network/schema/allele.jsonld",
  "@id": "http://reg.genome.network/allele/CA400345564",
  "communityStandardTitle": [
    "NM_058216.3(RAD51C):c.571+1G>C"
  ],
  "externalRecords": {
    "ClinVarAlleles": [
      {
        "@id": "http://www.ncbi.nlm.nih.gov/clinvar/?term=3829778[alleleid]",
        "alleleId": 3829778,
        "preferredName": "NM_058216.3(RAD51C):c.571+1G>C"
      }
    ],
    "ClinVarVariations": [
      {
        "@id": "http://www.ncbi.nlm.nih.gov/clinvar/variation/3698184",
        "RCV": [
          "RCV005177486"
        ],
        "variationId": 3698184
      }
    ],
    "MyVariantInfo_hg19": [
      {
        "@id": "http://myvariant.info/v1/variant/chr17:g.56774221G>C?assembly=hg19",
        "id": "chr17:g.56774221G>C"
      }
    ],
    "MyVariantInfo_hg38": [
      {
        "@id": "http://myvariant.info/v1/variant/chr17:g.58696860G>C?assembly=hg38",
        "id": "chr17:g.58696860G>C"
      }
    ],
    "dbSNP": [
      {
        "@id": "http://www.ncbi.nlm.nih.gov/snp/746870368",
        "rs": 746870368
      }
    ]
  },
  "genomicAlleles": [
    {
      "chromosome": "17",
      "coordinates": [
        {
          "allele": "C",
          "end": 58696860,
          "referenceAllele": "G",
          "start": 58696859
        }
      ],
      "hgvs": [
        "NC_000017.11:g.58696860G>C",
        "CM000679.2:g.58696860G>C"
      ],
      "referenceGenome": "GRCh38",
      "referenceSequence": "http://reg.genome.network/refseq/RS000065"
    },
    {
      "chromosome": "17",
      "coordinates": [
        {
          "allele": "C",
          "end": 56774221,
          "referenceAllele": "G",
          "start": 56774220
        }
      ],
      "hgvs": [
        "NC_000017.10:g.56774221G>C",
        "CM000679.1:g.56774221G>C"
      ],
      "referenceGenome": "GRCh37",
      "referenceSequence": "http://reg.genome.network/refseq/RS000041"
    },
    {
      "chromosome": "17",
      "coordinates": [
        {
          "allele": "C",
          "end": 54129220,
          "referenceAllele": "G",
          "start": 54129219
        }
      ],
      "hgvs": [
        "NC_000017.9:g.54129220G>C"
      ],
      "referenceGenome": "NCBI36",
      "referenceSequence": "http://reg.genome.network/refseq/RS000017"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 9259,
          "referenceAllele": "G",
          "start": 9258
        }
      ],
      "hgvs": [
        "NG_023199.1:g.9259G>C",
        "LRG_314:g.9259G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS003709"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 220,
          "referenceAllele": "C",
          "start": 219
        }
      ],
      "hgvs": [
        "NG_047169.1:g.220C>G"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS616688"
    }
  ],
  "transcriptAlleles": [
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 539,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 539,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000461271.6:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000464056.2:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS905081"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 3169,
          "referenceAllele": "G",
          "start": 3168
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697675.1:n.3169G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908896"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 631,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 631,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697676.1:n.631+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908897"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1652,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1652,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697677.1:n.1652+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908898"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 473,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 473,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697678.1:n.473+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908899"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1645,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1645,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697679.1:n.1645+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908900"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1645,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1645,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697680.1:c.*1435+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513392.1:n.*1435+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908901"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1672,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1672,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697681.1:c.*1462+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513393.1:n.*1462+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908902"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1659,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1659,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697683.1:c.*1435+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513395.1:n.*1435+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908904"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 631,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 631,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697684.1:n.631+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908905"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1478,
          "endIntronDirection": "+",
          "endIntronOffset": 1671,
          "referenceAllele": "G",
          "start": 1478,
          "startIntronDirection": "+",
          "startIntronOffset": 1670
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697685.1:c.*1268+1671G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513396.1:n.*1268+1671G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908906"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 463,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 463,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697686.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513397.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908907"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 450,
          "endIntronDirection": "+",
          "endIntronOffset": 1671,
          "referenceAllele": "G",
          "start": 450,
          "startIntronDirection": "+",
          "startIntronOffset": 1670
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697687.1:n.450+1671G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908908"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 617,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 617,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697688.1:n.617+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908909"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1308,
          "endIntronDirection": "+",
          "endIntronOffset": 1671,
          "referenceAllele": "G",
          "start": 1308,
          "startIntronDirection": "+",
          "startIntronOffset": 1670
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697689.1:c.*1107+1671G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513398.1:n.*1107+1671G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908910"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 613,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 613,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697690.1:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513399.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908911"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 795,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 795,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697691.1:c.*543+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513400.1:n.*543+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908912"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 754,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 754,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697692.1:c.*583+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513401.1:n.*583+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908913"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 663,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 663,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697694.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000513402.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS908915"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1178,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1178,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000697695.1:n.1178+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS908916"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 613,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 613,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000337432.9:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000336701.4:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS747657",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000337432.9:c.571+1G>C"
          },
          "RefSeq": {
            "hgvs": "NM_058216.3:c.571+1G>C"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000336701.4:n.571+1G>C"
          },
          "RefSeq": {
            "hgvs": "NP_478123.1:n.571+1G>C"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 642,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 642,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000337432.8:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000336701.4:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS260473"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 209,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 209,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000413590.5:c.209+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS283140"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 367,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 367,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000425173.5:c.367+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000407282.1:n.367+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS288633"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 539,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 539,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000461271.5:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000464056.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS305821"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1475,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1475,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000475762.5:c.*1274+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000432421.1:n.*1274+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS316969"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 433,
          "endIntronDirection": "+",
          "endIntronOffset": 1671,
          "referenceAllele": "G",
          "start": 433,
          "startIntronDirection": "+",
          "startIntronOffset": 1670
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000482007.5:c.404+1671G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000433332.1:n.404+1671G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS321806"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 442,
          "endIntronDirection": "+",
          "endIntronOffset": 1671,
          "referenceAllele": "G",
          "start": 442,
          "startIntronDirection": "+",
          "startIntronOffset": 1670
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000487525.5:c.404+1671G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000431637.1:n.404+1671G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS326071"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 483,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 483,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000487921.5:n.483+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS326367"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 642,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 642,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000583539.5:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000463121.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS387804"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 293,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 293,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000584617.5:c.293+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS388304"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 307,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 307,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "ENST00000622327.4:c.307+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000482326.1:n.307+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS405675"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 642,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 642,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "NM_058216.2:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_478123.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS040100"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 475,
          "endIntronDirection": "+",
          "endIntronOffset": 1671,
          "referenceAllele": "G",
          "start": 475,
          "startIntronDirection": "+",
          "startIntronOffset": 1670
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "NR_103872.1:n.475+1671G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS053118"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 644,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 644,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722001.2:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722064.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS074366"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 644,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 644,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722002.2:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722065.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS074367"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 536,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 536,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722004.2:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722067.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS074368"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 523,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 523,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722005.2:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722068.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS074369"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 822,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 822,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_011525092.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_011523394.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS092211"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 983,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 983,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_011525093.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_011523395.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS092212"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 584,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 584,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_011525094.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_011523396.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS092213"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 644,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 644,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XR_934513.1:n.644+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS129822"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 644,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 644,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XR_934514.1:n.644+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS129823"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1075,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1075,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722001.4:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722064.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS540440"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1075,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1075,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722002.4:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722065.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS540441"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 535,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 535,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722004.3:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722067.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS540442"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 521,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 521,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_006722005.3:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_006722068.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS540443"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 741,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 741,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_011525092.2:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_011523394.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS547728"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 902,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 902,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_011525093.2:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_011523395.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS547729"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 590,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 590,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_011525094.2:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_011523396.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS547730"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 535,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 535,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_017024914.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_016880403.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS575355"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 887,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 887,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_017024915.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_016880404.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS575356"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 795,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 795,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_017024916.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_016880405.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS575357"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 520,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 520,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_017024917.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_016880406.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS575358"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 753,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 753,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_017024918.2:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_016880407.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS575359"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 902,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 902,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XM_017024919.1:c.220+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_016880408.1:n.220+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS575360"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1075,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1075,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XR_934513.3:n.1075+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS610716"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 1075,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 1075,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "XR_934514.3:n.1075+1G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS610717"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 613,
          "endIntronDirection": "+",
          "endIntronOffset": 1,
          "referenceAllele": "G",
          "start": 613,
          "startIntronDirection": "+",
          "startIntronOffset": 0
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "NM_058216.3:c.571+1G>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_478123.1:n.571+1G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS671701",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000337432.9:c.571+1G>C"
          },
          "RefSeq": {
            "hgvs": "NM_058216.3:c.571+1G>C"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000336701.4:n.571+1G>C"
          },
          "RefSeq": {
            "hgvs": "NP_478123.1:n.571+1G>C"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 446,
          "endIntronDirection": "+",
          "endIntronOffset": 1671,
          "referenceAllele": "G",
          "start": 446,
          "startIntronDirection": "+",
          "startIntronOffset": 1670
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009820",
      "geneNCBI_id": 5889,
      "geneSymbol": "RAD51C",
      "hgvs": [
        "NR_103872.2:n.446+1671G>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS702892"
    }
  ],
  "type": "nucleotide"
}