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          "start": 6790,
          "startIntronDirection": "-",
          "startIntronOffset": 2
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007765",
      "geneNCBI_id": 4763,
      "geneSymbol": "NF1",
      "hgvs": [
        "XM_011524857.1:c.6458-2A>C"
      ],
      "proteinEffect": {
        "hgvs": "XP_011523159.1:n.6458-2A>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS091977"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 6760,
          "endIntronDirection": "-",
          "endIntronOffset": 1,
          "referenceAllele": "A",
          "start": 6760,
          "startIntronDirection": "-",
          "startIntronOffset": 2
        }
      ],
      "gene": "http://reg.genome.network/gene/GN007765",
      "geneNCBI_id": 4763,
      "geneSymbol": "NF1",
      "hgvs": [
        "NM_001042492.3:c.6428-2A>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_001035957.1:n.6428-2A>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS676037",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000358273.9:c.6428-2A>C"
          },
          "RefSeq": {
            "hgvs": "NM_001042492.3:c.6428-2A>C"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000351015.4:n.6428-2A>C"
          },
          "RefSeq": {
            "hgvs": "NP_001035957.1:n.6428-2A>C"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}