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        "NM_001378891.1:c.1121G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_001365820.1:p.Gly374Asp",
        "hgvsWellDefined": "NP_001365820.1:p.Gly374Asp"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS721857"
    },
    {
      "coordinates": [
        {
          "allele": "A",
          "end": 1407,
          "referenceAllele": "G",
          "start": 1406
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010261",
      "geneNCBI_id": 6098,
      "geneSymbol": "ROS1",
      "hgvs": [
        "NM_001378902.1:c.1121G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_001365831.1:p.Gly374Asp",
        "hgvsWellDefined": "NP_001365831.1:p.Gly374Asp"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS721858",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000368507.8:c.1121G>A"
          },
          "RefSeq": {
            "hgvs": "NM_001378902.1:c.1121G>A"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000357493.3:p.Gly374Asp"
          },
          "RefSeq": {
            "hgvs": "NP_001365831.1:p.Gly374Asp"
          }
        }
      }
    },
    {
      "@id": "http://reg.genome.network/allele/PA3072140192",
      "coordinates": [
        {
          "allele": "A",
          "end": 1380,
          "referenceAllele": "G",
          "start": 1379
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010261",
      "geneNCBI_id": 6098,
      "geneSymbol": "ROS1",
      "hgvs": [
        "NM_002944.3:c.1094G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_002935.2:p.Gly365Asp",
        "hgvsWellDefined": "NP_002935.2:p.Gly365Asp"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS727338"
    }
  ],
  "type": "nucleotide"
}