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        "XM_011538635.2:c.2004C>G"
      ],
      "proteinEffect": {
        "hgvs": "XP_011536937.1:p.Phe668Leu",
        "hgvsWellDefined": "XP_011536937.1:p.Phe668Leu"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS553339"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 2673,
          "referenceAllele": "C",
          "start": 2672
        }
      ],
      "gene": "http://reg.genome.network/gene/GN018083",
      "geneNCBI_id": 59341,
      "geneSymbol": "TRPV4",
      "hgvs": [
        "XM_017019774.1:c.1851C>G"
      ],
      "proteinEffect": {
        "hgvs": "XP_016875263.1:p.Phe617Leu",
        "hgvsWellDefined": "XP_016875263.1:p.Phe617Leu"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS571368"
    },
    {
      "@id": "http://reg.genome.network/allele/PA108589",
      "coordinates": [
        {
          "allele": "G",
          "end": 1931,
          "referenceAllele": "C",
          "start": 1930
        }
      ],
      "gene": "http://reg.genome.network/gene/GN018083",
      "geneNCBI_id": 59341,
      "geneSymbol": "TRPV4",
      "hgvs": [
        "NM_021625.5:c.1851C>G"
      ],
      "proteinEffect": {
        "hgvs": "NP_067638.3:p.Phe617Leu",
        "hgvsWellDefined": "NP_067638.3:p.Phe617Leu"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698429",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000261740.7:c.1851C>G"
          },
          "RefSeq": {
            "hgvs": "NM_021625.5:c.1851C>G"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000261740.2:p.Phe617Leu"
          },
          "RefSeq": {
            "hgvs": "NP_067638.3:p.Phe617Leu"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}