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      "proteinEffect": {
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        "hgvsWellDefined": "NP_001230714.1:p.Arg148_Asp527delinsGlyLysSerMetGlyValLeuPheGlyGlyArgSerTyrMetProSerThrHisArgThrThrGluLysTrpAsnSerValAlaAspCysLeuProCysValPheLeuValAspPheGluPheGlyCysAlaThrSerTyrIleLeuProGluLeuGlnAspGlyLeuSerPheHisValSerIleAlaLysAsnAspThrIleTyrIleLeuGlyGlyHisSerLeuAlaAsnAsnIleArgProAlaAsnLeuTyrArgIleArgValAspLeuProLeuGlySerProAlaValAsnCysThrValLeuProGlyGlyIleSerValSerSerAlaIleLeuThrGlnThrAsnAsnAspGluPheValIleValGlyGlyTyrGlnLeuGluAsnGlnLysArgMetIleCysAsnIleIleSerLeuGluAspAsnLysIleGluIleArgGluMetGluThrProAspTrpThrProAspIleLysHisSerLysIleTrpPheGlySerAsnMetGlyAsnGlyThrValPheLeuGlyIleProGlyAspAsnLysGlnValValSerGluGlyPheTyrPheTyrMetLeuLysCysAlaGluAspAspThrAsnGluGluGlnThrThrPheThrAsnSerGlnThrSerThrGluAspProGlyAspSerThrProPheGluAspSerGluGluPheCysPheSerAlaGluAlaAsnSerPheAspGlyAspAspGluPheAspThrTyrAsnGluAspAspGluGluAspGluSerGluThrGlyTyrTrpIleThrCysCysProThrCysAspValAspIleAsnThrTrpValProPheTyrSerThrGluLeuAsnLysProAlaMetIleTyrCysSerHisGlyAspGlyHisTrpValHisAlaGlnCysMetAspLeuAlaGluArgThrLeuIleHisLeuSerAlaGlySerAsnLysTyrTyrCysAsnGluHisValGluIleAlaArgAlaLeuHisThrProGlnArgValLeuProLeuLysLysProProMetLysSerLeuArgLysLysGlySerGlyLysIleLeuThrProAlaLysLysSerPheLeuArgArgLeuPheAspTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS018614"
    },
    {
      "@id": "http://reg.genome.network/allele/PA2499242519",
      "coordinates": [
        {
          "allele": "T",
          "end": 1036,
          "referenceAllele": "C",
          "start": 1035
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009832",
      "geneNCBI_id": 5897,
      "geneSymbol": "RAG2",
      "hgvs": [
        "NM_001243786.1:c.442C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001230715.1:p.Arg148Ter",
        "hgvsWellDefined": "NP_001230715.1:p.Arg148_Asp527delinsGlyLysSerMetGlyValLeuPheGlyGlyArgSerTyrMetProSerThrHisArgThrThrGluLysTrpAsnSerValAlaAspCysLeuProCysValPheLeuValAspPheGluPheGlyCysAlaThrSerTyrIleLeuProGluLeuGlnAspGlyLeuSerPheHisValSerIleAlaLysAsnAspThrIleTyrIleLeuGlyGlyHisSerLeuAlaAsnAsnIleArgProAlaAsnLeuTyrArgIleArgValAspLeuProLeuGlySerProAlaValAsnCysThrValLeuProGlyGlyIleSerValSerSerAlaIleLeuThrGlnThrAsnAsnAspGluPheValIleValGlyGlyTyrGlnLeuGluAsnGlnLysArgMetIleCysAsnIleIleSerLeuGluAspAsnLysIleGluIleArgGluMetGluThrProAspTrpThrProAspIleLysHisSerLysIleTrpPheGlySerAsnMetGlyAsnGlyThrValPheLeuGlyIleProGlyAspAsnLysGlnValValSerGluGlyPheTyrPheTyrMetLeuLysCysAlaGluAspAspThrAsnGluGluGlnThrThrPheThrAsnSerGlnThrSerThrGluAspProGlyAspSerThrProPheGluAspSerGluGluPheCysPheSerAlaGluAlaAsnSerPheAspGlyAspAspGluPheAspThrTyrAsnGluAspAspGluGluAspGluSerGluThrGlyTyrTrpIleThrCysCysProThrCysAspValAspIleAsnThrTrpValProPheTyrSerThrGluLeuAsnLysProAlaMetIleTyrCysSerHisGlyAspGlyHisTrpValHisAlaGlnCysMetAspLeuAlaGluArgThrLeuIleHisLeuSerAlaGlySerAsnLysTyrTyrCysAsnGluHisValGluIleAlaArgAlaLeuHisThrProGlnArgValLeuProLeuLysLysProProMetLysSerLeuArgLysLysGlySerGlyLysIleLeuThrProAlaLysLysSerPheLeuArgArgLeuPheAspTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS018615"
    },
    {
      "@id": "http://reg.genome.network/allele/PA2825193934",
      "coordinates": [
        {
          "allele": "T",
          "end": 604,
          "referenceAllele": "C",
          "start": 603
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009832",
      "geneNCBI_id": 5897,
      "geneSymbol": "RAG2",
      "hgvs": [
        "NM_000536.4:c.442C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_000527.2:p.Arg148Ter",
        "hgvsWellDefined": "NP_000527.2:p.Arg148_Asp527delinsGlyLysSerMetGlyValLeuPheGlyGlyArgSerTyrMetProSerThrHisArgThrThrGluLysTrpAsnSerValAlaAspCysLeuProCysValPheLeuValAspPheGluPheGlyCysAlaThrSerTyrIleLeuProGluLeuGlnAspGlyLeuSerPheHisValSerIleAlaLysAsnAspThrIleTyrIleLeuGlyGlyHisSerLeuAlaAsnAsnIleArgProAlaAsnLeuTyrArgIleArgValAspLeuProLeuGlySerProAlaValAsnCysThrValLeuProGlyGlyIleSerValSerSerAlaIleLeuThrGlnThrAsnAsnAspGluPheValIleValGlyGlyTyrGlnLeuGluAsnGlnLysArgMetIleCysAsnIleIleSerLeuGluAspAsnLysIleGluIleArgGluMetGluThrProAspTrpThrProAspIleLysHisSerLysIleTrpPheGlySerAsnMetGlyAsnGlyThrValPheLeuGlyIleProGlyAspAsnLysGlnValValSerGluGlyPheTyrPheTyrMetLeuLysCysAlaGluAspAspThrAsnGluGluGlnThrThrPheThrAsnSerGlnThrSerThrGluAspProGlyAspSerThrProPheGluAspSerGluGluPheCysPheSerAlaGluAlaAsnSerPheAspGlyAspAspGluPheAspThrTyrAsnGluAspAspGluGluAspGluSerGluThrGlyTyrTrpIleThrCysCysProThrCysAspValAspIleAsnThrTrpValProPheTyrSerThrGluLeuAsnLysProAlaMetIleTyrCysSerHisGlyAspGlyHisTrpValHisAlaGlnCysMetAspLeuAlaGluArgThrLeuIleHisLeuSerAlaGlySerAsnLysTyrTyrCysAsnGluHisValGluIleAlaArgAlaLeuHisThrProGlnArgValLeuProLeuLysLysProProMetLysSerLeuArgLysLysGlySerGlyLysIleLeuThrProAlaLysLysSerPheLeuArgArgLeuPheAspTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS674882",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000311485.8:c.442C>T"
          },
          "RefSeq": {
            "hgvs": "NM_000536.4:c.442C>T"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000308620.4:p.Arg148Ter"
          },
          "RefSeq": {
            "hgvs": "NP_000527.2:p.Arg148Ter"
          }
        }
      }
    },
    {
      "@id": "http://reg.genome.network/allele/PA2826339003",
      "coordinates": [
        {
          "allele": "T",
          "end": 799,
          "referenceAllele": "C",
          "start": 798
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009832",
      "geneNCBI_id": 5897,
      "geneSymbol": "RAG2",
      "hgvs": [
        "NM_001243785.2:c.442C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001230714.1:p.Arg148Ter",
        "hgvsWellDefined": "NP_001230714.1:p.Arg148_Asp527delinsGlyLysSerMetGlyValLeuPheGlyGlyArgSerTyrMetProSerThrHisArgThrThrGluLysTrpAsnSerValAlaAspCysLeuProCysValPheLeuValAspPheGluPheGlyCysAlaThrSerTyrIleLeuProGluLeuGlnAspGlyLeuSerPheHisValSerIleAlaLysAsnAspThrIleTyrIleLeuGlyGlyHisSerLeuAlaAsnAsnIleArgProAlaAsnLeuTyrArgIleArgValAspLeuProLeuGlySerProAlaValAsnCysThrValLeuProGlyGlyIleSerValSerSerAlaIleLeuThrGlnThrAsnAsnAspGluPheValIleValGlyGlyTyrGlnLeuGluAsnGlnLysArgMetIleCysAsnIleIleSerLeuGluAspAsnLysIleGluIleArgGluMetGluThrProAspTrpThrProAspIleLysHisSerLysIleTrpPheGlySerAsnMetGlyAsnGlyThrValPheLeuGlyIleProGlyAspAsnLysGlnValValSerGluGlyPheTyrPheTyrMetLeuLysCysAlaGluAspAspThrAsnGluGluGlnThrThrPheThrAsnSerGlnThrSerThrGluAspProGlyAspSerThrProPheGluAspSerGluGluPheCysPheSerAlaGluAlaAsnSerPheAspGlyAspAspGluPheAspThrTyrAsnGluAspAspGluGluAspGluSerGluThrGlyTyrTrpIleThrCysCysProThrCysAspValAspIleAsnThrTrpValProPheTyrSerThrGluLeuAsnLysProAlaMetIleTyrCysSerHisGlyAspGlyHisTrpValHisAlaGlnCysMetAspLeuAlaGluArgThrLeuIleHisLeuSerAlaGlySerAsnLysTyrTyrCysAsnGluHisValGluIleAlaArgAlaLeuHisThrProGlnArgValLeuProLeuLysLysProProMetLysSerLeuArgLysLysGlySerGlyLysIleLeuThrProAlaLysLysSerPheLeuArgArgLeuPheAspTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS680268"
    },
    {
      "@id": "http://reg.genome.network/allele/PA2499242519",
      "coordinates": [
        {
          "allele": "T",
          "end": 993,
          "referenceAllele": "C",
          "start": 992
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009832",
      "geneNCBI_id": 5897,
      "geneSymbol": "RAG2",
      "hgvs": [
        "NM_001243786.2:c.442C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001230715.1:p.Arg148Ter",
        "hgvsWellDefined": "NP_001230715.1:p.Arg148_Asp527delinsGlyLysSerMetGlyValLeuPheGlyGlyArgSerTyrMetProSerThrHisArgThrThrGluLysTrpAsnSerValAlaAspCysLeuProCysValPheLeuValAspPheGluPheGlyCysAlaThrSerTyrIleLeuProGluLeuGlnAspGlyLeuSerPheHisValSerIleAlaLysAsnAspThrIleTyrIleLeuGlyGlyHisSerLeuAlaAsnAsnIleArgProAlaAsnLeuTyrArgIleArgValAspLeuProLeuGlySerProAlaValAsnCysThrValLeuProGlyGlyIleSerValSerSerAlaIleLeuThrGlnThrAsnAsnAspGluPheValIleValGlyGlyTyrGlnLeuGluAsnGlnLysArgMetIleCysAsnIleIleSerLeuGluAspAsnLysIleGluIleArgGluMetGluThrProAspTrpThrProAspIleLysHisSerLysIleTrpPheGlySerAsnMetGlyAsnGlyThrValPheLeuGlyIleProGlyAspAsnLysGlnValValSerGluGlyPheTyrPheTyrMetLeuLysCysAlaGluAspAspThrAsnGluGluGlnThrThrPheThrAsnSerGlnThrSerThrGluAspProGlyAspSerThrProPheGluAspSerGluGluPheCysPheSerAlaGluAlaAsnSerPheAspGlyAspAspGluPheAspThrTyrAsnGluAspAspGluGluAspGluSerGluThrGlyTyrTrpIleThrCysCysProThrCysAspValAspIleAsnThrTrpValProPheTyrSerThrGluLeuAsnLysProAlaMetIleTyrCysSerHisGlyAspGlyHisTrpValHisAlaGlnCysMetAspLeuAlaGluArgThrLeuIleHisLeuSerAlaGlySerAsnLysTyrTyrCysAsnGluHisValGluIleAlaArgAlaLeuHisThrProGlnArgValLeuProLeuLysLysProProMetLysSerLeuArgLysLysGlySerGlyLysIleLeuThrProAlaLysLysSerPheLeuArgArgLeuPheAspTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS714525"
    }
  ],
  "type": "nucleotide"
}