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  "communityStandardTitle": [
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        "hgvsWellDefined": "NP_001160022.1:p.Glu184_Pro460delinsAspValGlnAlaLeuAsnIleSerValProTyrGlyProIleProValAspPheGlnArgLysIleArgGlnSerTyrPheAlaSerValSerTyrLeuAspThrGlnValGlyArgLeuLeuSerAlaLeuAspAspLeuGlnLeuAlaAsnSerThrIleIleAlaPheThrSerAspHisGlyTrpAlaLeuGlyGluHisGlyGluTrpAlaLysTyrSerAsnPheAspValAlaThrHisValProLeuIlePheTyrValProGlyArgThrAlaSerLeuProGluAlaGlyGluLysLeuPheProTyrLeuAspProPheAspSerAlaSerGlnLeuMetGluProGlyArgGlnSerMetAspLeuValGluLeuValSerLeuPheProThrLeuAlaGlyLeuAlaGlyLeuGlnValProProArgCysProValProSerPheHisValGluLeuCysArgGluGlyLysAsnLeuLeuLysHisPheArgPheArgAspLeuGluGluAspProTyrLeuProGlyAsnProArgGluLeuIleAlaTyrSerGlnTyrProArgProSerAspIleProGlnTrpAsnSerAspLysProSerLeuLysAspIleLysIleMetGlyTyrSerIleArgThrIleAspTyrArgTyrThrValTrpValGlyPheAsnProAspGluPheLeuAlaAsnPheSerAspIleHisAlaGlyGluLeuTyrPheValAspSerAspProLeuGlnAspHisAsnMetTyrAsnAspSerGlnGlyGlyAspLeuPheGlnLeuLeuMetProTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS511678"
    },
    {
      "@id": "http://reg.genome.network/allele/PA349094",
      "coordinates": [
        {
          "allele": "T",
          "end": 989,
          "referenceAllele": "G",
          "start": 988
        }
      ],
      "gene": "http://reg.genome.network/gene/GN005389",
      "geneNCBI_id": 3423,
      "geneSymbol": "IDS",
      "hgvs": [
        "NM_000202.8:c.820G>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_000193.1:p.Glu274Ter",
        "hgvsWellDefined": "NP_000193.1:p.Glu274_Pro550delinsAspValGlnAlaLeuAsnIleSerValProTyrGlyProIleProValAspPheGlnArgLysIleArgGlnSerTyrPheAlaSerValSerTyrLeuAspThrGlnValGlyArgLeuLeuSerAlaLeuAspAspLeuGlnLeuAlaAsnSerThrIleIleAlaPheThrSerAspHisGlyTrpAlaLeuGlyGluHisGlyGluTrpAlaLysTyrSerAsnPheAspValAlaThrHisValProLeuIlePheTyrValProGlyArgThrAlaSerLeuProGluAlaGlyGluLysLeuPheProTyrLeuAspProPheAspSerAlaSerGlnLeuMetGluProGlyArgGlnSerMetAspLeuValGluLeuValSerLeuPheProThrLeuAlaGlyLeuAlaGlyLeuGlnValProProArgCysProValProSerPheHisValGluLeuCysArgGluGlyLysAsnLeuLeuLysHisPheArgPheArgAspLeuGluGluAspProTyrLeuProGlyAsnProArgGluLeuIleAlaTyrSerGlnTyrProArgProSerAspIleProGlnTrpAsnSerAspLysProSerLeuLysAspIleLysIleMetGlyTyrSerIleArgThrIleAspTyrArgTyrThrValTrpValGlyPheAsnProAspGluPheLeuAlaAsnPheSerAspIleHisAlaGlyGluLeuTyrPheValAspSerAspProLeuGlnAspHisAsnMetTyrAsnAspSerGlnGlyGlyAspLeuPheGlnLeuLeuMetProTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662355",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000340855.11:c.820G>T"
          },
          "RefSeq": {
            "hgvs": "NM_000202.8:c.820G>T"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000339801.6:p.Glu274Ter"
          },
          "RefSeq": {
            "hgvs": "NP_000193.1:p.Glu274Ter"
          }
        }
      }
    },
    {
      "@id": "http://reg.genome.network/allele/PA2826033144",
      "coordinates": [
        {
          "allele": "T",
          "end": 945,
          "referenceAllele": "G",
          "start": 944
        }
      ],
      "gene": "http://reg.genome.network/gene/GN005389",
      "geneNCBI_id": 3423,
      "geneSymbol": "IDS",
      "hgvs": [
        "NM_001166550.4:c.550G>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_001160022.1:p.Glu184Ter",
        "hgvsWellDefined": "NP_001160022.1:p.Glu184_Pro460delinsAspValGlnAlaLeuAsnIleSerValProTyrGlyProIleProValAspPheGlnArgLysIleArgGlnSerTyrPheAlaSerValSerTyrLeuAspThrGlnValGlyArgLeuLeuSerAlaLeuAspAspLeuGlnLeuAlaAsnSerThrIleIleAlaPheThrSerAspHisGlyTrpAlaLeuGlyGluHisGlyGluTrpAlaLysTyrSerAsnPheAspValAlaThrHisValProLeuIlePheTyrValProGlyArgThrAlaSerLeuProGluAlaGlyGluLysLeuPheProTyrLeuAspProPheAspSerAlaSerGlnLeuMetGluProGlyArgGlnSerMetAspLeuValGluLeuValSerLeuPheProThrLeuAlaGlyLeuAlaGlyLeuGlnValProProArgCysProValProSerPheHisValGluLeuCysArgGluGlyLysAsnLeuLeuLysHisPheArgPheArgAspLeuGluGluAspProTyrLeuProGlyAsnProArgGluLeuIleAlaTyrSerGlnTyrProArgProSerAspIleProGlnTrpAsnSerAspLysProSerLeuLysAspIleLysIleMetGlyTyrSerIleArgThrIleAspTyrArgTyrThrValTrpValGlyPheAsnProAspGluPheLeuAlaAsnPheSerAspIleHisAlaGlyGluLeuTyrPheValAspSerAspProLeuGlnAspHisAsnMetTyrAsnAspSerGlnGlyGlyAspLeuPheGlnLeuLeuMetProTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS678512"
    },
    {
      "@id": "http://reg.genome.network/allele/PA916012792",
      "coordinates": [
        {
          "allele": "T",
          "end": 989,
          "referenceAllele": "G",
          "start": 988
        }
      ],
      "gene": "http://reg.genome.network/gene/GN005389",
      "geneNCBI_id": 3423,
      "geneSymbol": "IDS",
      "hgvs": [
        "NM_006123.5:c.820G>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_006114.1:p.Glu274Ter",
        "hgvsWellDefined": "NP_006114.1:p.Glu274_Thr343delinsAspValGlnAlaLeuAsnIleSerValProTyrGlyProIleProValAspPheGlnArgLysIleArgGlnSerTyrPheAlaSerValSerTyrLeuAspThrGlnValGlyArgLeuLeuSerAlaLeuAspAspLeuGlnLeuAlaAsnSerThrIleIleAlaPheThrSerAspHisGlyPheLeuMetArgThrAsnThrTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS696619"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 989,
          "referenceAllele": "G",
          "start": 988
        }
      ],
      "gene": "http://reg.genome.network/gene/GN005389",
      "geneNCBI_id": 3423,
      "geneSymbol": "IDS",
      "hgvs": [
        "NR_104128.2:n.989G>T"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS702935"
    }
  ],
  "type": "nucleotide"
}