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          "start": 1561
        }
      ],
      "gene": "http://reg.genome.network/gene/GN000443",
      "geneNCBI_id": 57679,
      "geneSymbol": "ALS2",
      "hgvs": [
        "XR_001738867.2:n.1562_1563del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS589307"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 681,
          "referenceAllele": "AG",
          "start": 679
        }
      ],
      "gene": "http://reg.genome.network/gene/GN000443",
      "geneNCBI_id": 57679,
      "geneSymbol": "ALS2",
      "hgvs": [
        "XR_002959320.1:n.680_681del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS605253"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1545,
          "referenceAllele": "AG",
          "start": 1543
        }
      ],
      "gene": "http://reg.genome.network/gene/GN000443",
      "geneNCBI_id": 57679,
      "geneSymbol": "ALS2",
      "hgvs": [
        "NM_020919.4:c.1427_1428del"
      ],
      "proteinEffect": {
        "hgvs": "NP_065970.2:p.Glu476GlyfsTer?"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS670148",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000264276.11:c.1427_1428del"
          },
          "RefSeq": {
            "hgvs": "NM_020919.4:c.1427_1428del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000264276.6:p.Glu476GlyfsTer?"
          },
          "RefSeq": {
            "hgvs": "NP_065970.2:p.Glu476GlyfsTer?"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}