{
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  "communityStandardTitle": [
    "NM_005236.3(ERCC4):c.2305_2377del (p.Leu769PhefsTer24)"
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      "referenceSequence": "http://reg.genome.network/refseq/RS828925"
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    {
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      },
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    {
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS256598"
    },
    {
      "coordinates": [
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          "start": 1581
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      "gene": "http://reg.genome.network/gene/GN003436",
      "geneNCBI_id": 2072,
      "geneSymbol": "ERCC4",
      "hgvs": [
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      "referenceSequence": "http://reg.genome.network/refseq/RS274156"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "CTCACTTCCCGAGGTGCCTTGTTTCAGGAGATCTCCAGCAATGACATTAGTTCCAAACTCACTCTTCTTACAC",
          "start": 617
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      ],
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      "hgvs": [
        "ENST00000462862.1:c.618_690del"
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      "proteinEffect": {
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      "referenceSequence": "http://reg.genome.network/refseq/RS307027"
    },
    {
      "coordinates": [
        {
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          "referenceAllele": "CTCACTTCCCGAGGTGCCTTGTTTCAGGAGATCTCCAGCAATGACATTAGTTCCAAACTCACTCTTCTTACAC",
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      ],
      "gene": "http://reg.genome.network/gene/GN003436",
      "geneNCBI_id": 2072,
      "geneSymbol": "ERCC4",
      "hgvs": [
        "NM_005236.2:c.2305_2377del",
        "LRG_463t1:c.2305_2377del"
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        "hgvsWellDefined": "NP_005227.1:p.[Leu769Phe;Arg772_Leu775delinsProAspTyrGly;Gln777_Ile779del;Ser781_Lys787delinsGlyAlaPro;Thr789del;Leu791_Pro796delinsMetGln;Leu798del;Ile800_Trp802delinsSer;Pro804_Glu811del;Phe813_Gln818delinsArg;Lys820_Gln822del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS030348"
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    {
      "coordinates": [
        {
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          "referenceAllele": "CTCACTTCCCGAGGTGCCTTGTTTCAGGAGATCTCCAGCAATGACATTAGTTCCAAACTCACTCTTCTTACAC",
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      "gene": "http://reg.genome.network/gene/GN003436",
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        "hgvsWellDefined": "XP_011520726.1:p.[Leu815Phe;Arg818_Leu821delinsProAspTyrGly;Gln823_Ile825del;Ser827_Lys833delinsGlyAlaPro;Thr835del;Leu837_Pro842delinsMetGln;Leu844del;Ile846_Trp848delinsSer;Pro850_Glu857del;Phe859_Gln864delinsArg;Lys866_Gln868del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS089576"
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    {
      "coordinates": [
        {
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          "referenceAllele": "CTCACTTCCCGAGGTGCCTTGTTTCAGGAGATCTCCAGCAATGACATTAGTTCCAAACTCACTCTTCTTACAC",
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      "hgvs": [
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      "proteinEffect": {
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        "hgvsWellDefined": "XP_011520727.1:p.[Leu588Phe;Arg591_Leu594delinsProAspTyrGly;Gln596_Ile598del;Ser600_Lys606delinsGlyAlaPro;Thr608del;Leu610_Pro615delinsMetGln;Leu617del;Ile619_Trp621delinsSer;Pro623_Glu630del;Phe632_Gln637delinsArg;Lys639_Gln641del]"
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      "referenceSequence": "http://reg.genome.network/refseq/RS089577"
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    {
      "coordinates": [
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        "hgvsWellDefined": "XP_011520728.1:p.[Leu506Phe;Arg509_Leu512delinsProAspTyrGly;Gln514_Ile516del;Ser518_Lys524delinsGlyAlaPro;Thr526del;Leu528_Pro533delinsMetGln;Leu535del;Ile537_Trp539delinsSer;Pro541_Glu548del;Phe550_Gln555delinsArg;Lys557_Gln559del]"
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      "referenceSequence": "http://reg.genome.network/refseq/RS089578"
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    {
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      "proteinEffect": {
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        "hgvsWellDefined": "XP_011520729.1:p.[Leu319Phe;Arg322_Leu325delinsProAspTyrGly;Gln327_Ile329del;Ser331_Lys337delinsGlyAlaPro;Thr339del;Leu341_Pro346delinsMetGln;Leu348del;Ile350_Trp352delinsSer;Pro354_Glu361del;Phe363_Gln368delinsArg;Lys370_Gln372del]"
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      "referenceSequence": "http://reg.genome.network/refseq/RS089579"
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    {
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      "referenceSequence": "http://reg.genome.network/refseq/RS128721"
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    {
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      "referenceSequence": "http://reg.genome.network/refseq/RS546577"
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    {
      "coordinates": [
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      "referenceSequence": "http://reg.genome.network/refseq/RS573869"
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    {
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      "proteinEffect": {
        "hgvs": "NP_005227.1:p.Leu769PhefsTer24",
        "hgvsWellDefined": "NP_005227.1:p.[Leu769Phe;Arg772_Leu775delinsProAspTyrGly;Gln777_Ile779del;Ser781_Lys787delinsGlyAlaPro;Thr789del;Leu791_Pro796delinsMetGln;Leu798del;Ile800_Trp802delinsSer;Pro804_Glu811del;Phe813_Gln818delinsArg;Lys820_Gln822del]"
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      "referenceSequence": "http://reg.genome.network/refseq/RS696357",
      "MANE": {
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        "maneStatus": "MANE Select",
        "nucleotide": {
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            "hgvs": "ENST00000311895.8:c.2305_2377del"
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          "RefSeq": {
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        "protein": {
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            "hgvs": "NP_005227.1:p.Leu769PhefsTer24"
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    }
  ],
  "type": "nucleotide"
}