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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556316"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3790,
          "referenceAllele": "GT",
          "start": 3788
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545948.2:c.2612_2613del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544250.1:p.Gly871AspfsTer23",
        "hgvsWellDefined": "XP_011544250.1:p.[Gly871_Asp873delinsAspArgLeu;His875_Leu877delinsPhe;Gln880delinsTrpThr;Asp882_Asn884delinsArgTrpLysTyr;Phe886_Tyr890delinsCysIleProLeuPheIle]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556317"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 4231,
          "referenceAllele": "GT",
          "start": 4229
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023671.1:c.3266_3267del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879160.1:p.Gly1089AspfsTer23",
        "hgvsWellDefined": "XP_016879160.1:p.[Gly1089_Asp1091delinsAspArgLeu;His1093_Leu1095delinsPhe;Gln1098delinsTrpThr;Asp1100_Asn1102delinsArgTrpLysTyr;Phe1104_Tyr1108delinsCysIleProLeuPheIle]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574393"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3441,
          "referenceAllele": "GT",
          "start": 3439
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023672.2:c.3260_3261del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879161.1:p.Gly1087AspfsTer23",
        "hgvsWellDefined": "XP_016879161.1:p.[Gly1087_Asp1089delinsAspArgLeu;His1091_Leu1093delinsPhe;Gln1096delinsTrpThr;Asp1098_Asn1100delinsArgTrpLysTyr;Phe1102_Tyr1106delinsCysIleProLeuPheIle]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574394"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3529,
          "referenceAllele": "GT",
          "start": 3527
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023673.2:c.*132_*133del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879162.1:n.*132_*133del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574395"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3651,
          "referenceAllele": "GT",
          "start": 3649
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "NM_024675.4:c.3497_3498del"
      ],
      "proteinEffect": {
        "hgvs": "NP_078951.2:p.Gly1166AspfsTer23",
        "hgvsWellDefined": "NP_078951.2:p.[Gly1166_Asp1168delinsAspArgLeu;His1170_Leu1172delinsPhe;Gln1175delinsTrpThr;Asp1177_Asn1179delinsArgTrpLysTyr;Phe1181_Tyr1185delinsCysIleProLeuPheIle]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698739",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000261584.9:c.3497_3498del"
          },
          "RefSeq": {
            "hgvs": "NM_024675.4:c.3497_3498del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000261584.4:p.Gly1166AspfsTer23"
          },
          "RefSeq": {
            "hgvs": "NP_078951.2:p.Gly1166AspfsTer23"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}