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      "geneNCBI_id": 4204,
      "geneSymbol": "MECP2",
      "hgvs": [
        "NM_001369393.2:c.873_916del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001356322.1:p.Pro292HisfsTer5",
        "hgvsWellDefined": "NP_001356322.1:p.[Pro292_Leu293delinsHisGln;Pro296_Gly335del]"
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      "referenceSequence": "http://reg.genome.network/refseq/RS691618"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "CCCTGCCCCCACCTCCACCTGAGCCCGAGAGCTCCGAGGACCAC",
          "start": 1282
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      "geneSymbol": "MECP2",
      "hgvs": [
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      ],
      "proteinEffect": {
        "hgvs": "NP_001356323.1:p.Pro292HisfsTer5",
        "hgvsWellDefined": "NP_001356323.1:p.[Pro292_Leu293delinsHisGln;Pro296_Gly335del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS691619"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1326,
          "referenceAllele": "CCCTGCCCCCACCTCCACCTGAGCCCGAGAGCTCCGAGGACCAC",
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      ],
      "gene": "http://reg.genome.network/gene/GN006990",
      "geneNCBI_id": 4204,
      "geneSymbol": "MECP2",
      "hgvs": [
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      "proteinEffect": {
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        "hgvsWellDefined": "NP_001356323.1:p.[Pro292_Leu293delinsHisGln;Pro296_Gly335del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS721143"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "CCCTGCCCCCACCTCCACCTGAGCCCGAGAGCTCCGAGGACCAC",
          "start": 1366
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      "gene": "http://reg.genome.network/gene/GN006990",
      "geneNCBI_id": 4204,
      "geneSymbol": "MECP2",
      "hgvs": [
        "NM_001386137.1:c.483_526del"
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      "proteinEffect": {
        "hgvs": "NP_001373066.1:p.Pro162HisfsTer5",
        "hgvsWellDefined": "NP_001373066.1:p.[Pro162_Leu163delinsHisGln;Pro166_Gly205del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS724415"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1298,
          "referenceAllele": "CCCTGCCCCCACCTCCACCTGAGCCCGAGAGCTCCGAGGACCAC",
          "start": 1254
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      ],
      "gene": "http://reg.genome.network/gene/GN006990",
      "geneNCBI_id": 4204,
      "geneSymbol": "MECP2",
      "hgvs": [
        "NM_001386138.1:c.483_526del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001373067.1:p.Pro162HisfsTer5",
        "hgvsWellDefined": "NP_001373067.1:p.[Pro162_Leu163delinsHisGln;Pro166_Gly205del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS724416"
    },
    {
      "coordinates": [
        {
          "allele": "",
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          "referenceAllele": "CCCTGCCCCCACCTCCACCTGAGCCCGAGAGCTCCGAGGACCAC",
          "start": 1130
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006990",
      "geneNCBI_id": 4204,
      "geneSymbol": "MECP2",
      "hgvs": [
        "NM_001386139.1:c.483_526del"
      ],
      "proteinEffect": {
        "hgvs": "NP_001373068.1:p.Pro162HisfsTer5",
        "hgvsWellDefined": "NP_001373068.1:p.[Pro162_Leu163delinsHisGln;Pro166_Gly205del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS724417"
    },
    {
      "coordinates": [
        {
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          "referenceAllele": "CCCTGCCCCCACCTCCACCTGAGCCCGAGAGCTCCGAGGACCAC",
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      "gene": "http://reg.genome.network/gene/GN006990",
      "geneNCBI_id": 4204,
      "geneSymbol": "MECP2",
      "hgvs": [
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      ],
      "proteinEffect": {
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        "hgvsWellDefined": "NP_004983.1:p.[Pro385_Leu386delinsHisGln;Pro389_Gly428del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS727571",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Plus Clinical",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000303391.11:c.1152_1195del"
          },
          "RefSeq": {
            "hgvs": "NM_004992.4:c.1152_1195del"
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        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000301948.6:p.Pro385HisfsTer5"
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    }
  ],
  "type": "nucleotide"
}