{
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  "communityStandardTitle": [
    "NM_000025.3(ADRB3):c.884dup (p.Leu296SerfsTer?)"
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        "@id": "http://www.ncbi.nlm.nih.gov/snp/2487766703",
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          "start": 37965588
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      "referenceSequence": "http://reg.genome.network/refseq/RS000056"
    },
    {
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          "referenceAllele": "",
          "start": 37823106
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      "referenceSequence": "http://reg.genome.network/refseq/RS000032"
    },
    {
      "chromosome": "8",
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          "referenceAllele": "",
          "start": 37942263
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      "referenceGenome": "NCBI36",
      "referenceSequence": "http://reg.genome.network/refseq/RS000008"
    },
    {
      "coordinates": [
        {
          "allele": "G",
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          "referenceAllele": "",
          "start": 6081
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      "hgvs": [
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      "referenceSequence": "http://reg.genome.network/refseq/RS002062"
    }
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      "coordinates": [
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          "referenceAllele": "",
          "start": 1014
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      ],
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          }
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        "protein": {
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    {
      "coordinates": [
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          "referenceAllele": "",
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      "referenceSequence": "http://reg.genome.network/refseq/RS758684"
    },
    {
      "coordinates": [
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          "start": 368
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      "hgvs": [
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      "proteinEffect": {
        "hgvs": "ENSP00000497740.1:p.Leu124SerfsTer?",
        "hgvsWellDefined": "ENSP00000497740.1:p.[Leu124_Met126delinsSerHisHis;Thr128_Thr130delinsHis;Cys132_Trp133delinsHisSer;Pro135_Phe137delinsLeuValAla;Ala139_Leu142delinsLeuSerGlyGln;Leu145delinsAlaArgPro;Ser149_Val151delinsLeuSerSer;Gly153dup]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS769701"
    },
    {
      "coordinates": [
        {
          "allele": "G",
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          "referenceAllele": "",
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      "gene": "http://reg.genome.network/gene/GN000288",
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        "ENST00000345060.4:c.884dup"
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        "hgvs": "ENSP00000343782.3:p.Leu296SerfsTer?",
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS262124"
    },
    {
      "coordinates": [
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          "referenceAllele": "",
          "start": 159
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      "gene": "http://reg.genome.network/gene/GN000288",
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      "geneSymbol": "ADRB3",
      "hgvs": [
        "ENST00000520341.1:n.159dup"
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      "referenceSequence": "http://reg.genome.network/refseq/RS347406"
    },
    {
      "coordinates": [
        {
          "allele": "G",
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          "referenceAllele": "",
          "start": 1081
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      ],
      "gene": "http://reg.genome.network/gene/GN000288",
      "geneNCBI_id": 155,
      "geneSymbol": "ADRB3",
      "hgvs": [
        "ENST00000614635.1:c.884dup"
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000480325.1:p.Leu296SerfsTer?",
        "hgvsWellDefined": "ENSP00000480325.1:p.[Leu296_Met298delinsSerHisHis;Thr300_Thr302delinsHis;Cys304_Trp305delinsHisSer;Pro307_Phe309delinsLeuValAla;Ala311_Leu314delinsLeuSerGlyGln;Leu317delinsAlaArgPro;Ser321_Val323delinsLeuSerSer;Gly325dup]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS402283"
    },
    {
      "coordinates": [
        {
          "allele": "G",
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          "referenceAllele": "",
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      "gene": "http://reg.genome.network/gene/GN000288",
      "geneNCBI_id": 155,
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      "hgvs": [
        "NM_000025.2:c.884dup"
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      "proteinEffect": {
        "hgvs": "NP_000016.1:p.Leu296SerfsTer?",
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS006090"
    },
    {
      "coordinates": [
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          "referenceAllele": "",
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      "gene": "http://reg.genome.network/gene/GN000288",
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      "hgvs": [
        "NM_000025.3:c.884dup"
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      "proteinEffect": {
        "hgvs": "NP_000016.1:p.Leu296SerfsTer?",
        "hgvsWellDefined": "NP_000016.1:p.[Leu296_Met298delinsSerHisHis;Thr300_Thr302delinsHis;Cys304_Trp305delinsHisSer;Pro307_Phe309delinsLeuValAla;Ala311_Leu314delinsLeuSerGlyGln;Leu317delinsAlaArgPro;Ser321_Val323delinsLeuSerSer;Gly325dup]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662288",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000345060.5:c.884dup"
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          "RefSeq": {
            "hgvs": "NM_000025.3:c.884dup"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000343782.3:p.Leu296SerfsTer?"
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          "RefSeq": {
            "hgvs": "NP_000016.1:p.Leu296SerfsTer?"
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        }
      }
    }
  ],
  "type": "nucleotide"
}