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      "proteinEffect": {
        "hgvs": "NP_001341624.1:p.Leu137SerfsTer26",
        "hgvsWellDefined": "NP_001341624.1:p.[Leu137del;Gln139Pro;Gln141Gly;Ser143_Thr146delinsGlyArgHis;Asn148_His150delinsHisLeu;Val152del;Thr155_Ala166delinsTrpSerAlaProProCysLeuTrpThrAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720551"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1082,
          "referenceAllele": "C",
          "start": 1081
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009829",
      "geneNCBI_id": 5894,
      "geneSymbol": "RAF1",
      "hgvs": [
        "NM_002880.4:c.751del"
      ],
      "proteinEffect": {
        "hgvs": "NP_002871.1:p.Leu251SerfsTer26",
        "hgvsWellDefined": "NP_002871.1:p.[Leu251del;Gln253Pro;Gln255Gly;Ser257_Thr260delinsGlyArgHis;Asn262_His264delinsHisLeu;Val266del;Thr269_Ala280delinsTrpSerAlaProProCysLeuTrpThrAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS727324",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000251849.9:c.751del"
          },
          "RefSeq": {
            "hgvs": "NM_002880.4:c.751del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000251849.4:p.Leu251SerfsTer26"
          },
          "RefSeq": {
            "hgvs": "NP_002871.1:p.Leu251SerfsTer26"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1082,
          "referenceAllele": "C",
          "start": 1081
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009829",
      "geneNCBI_id": 5894,
      "geneSymbol": "RAF1",
      "hgvs": [
        "NR_148940.3:n.1082del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS731498"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1082,
          "referenceAllele": "C",
          "start": 1081
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009829",
      "geneNCBI_id": 5894,
      "geneSymbol": "RAF1",
      "hgvs": [
        "NR_148941.3:n.1082del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS731499"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 1082,
          "referenceAllele": "C",
          "start": 1081
        }
      ],
      "gene": "http://reg.genome.network/gene/GN009829",
      "geneNCBI_id": 5894,
      "geneSymbol": "RAF1",
      "hgvs": [
        "NR_148942.3:n.1082del"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS731500"
    }
  ],
  "type": "nucleotide"
}