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      "referenceSequence": "http://reg.genome.network/refseq/RS082962"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 2942,
          "referenceAllele": "",
          "start": 2942
        }
      ],
      "gene": "http://reg.genome.network/gene/GN001884",
      "geneNCBI_id": 1080,
      "geneSymbol": "CFTR",
      "hgvs": [
        "XM_011515752.1:c.2900dup"
      ],
      "proteinEffect": {
        "hgvs": "XP_011514054.1:p.Val968GlyfsTer?",
        "hgvsWellDefined": "XP_011514054.1:p.[Val968_Val974delinsGlyAlaTyrSerAsnHis;Lys976_Ser985delinsValGluAsnPheThrProGlnAsn;Leu987_Met991delinsThrPheCysSerSer;Leu994delinsTyrVal;Thr996delinsProGlnHisVal]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS082963"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 3032,
          "referenceAllele": "",
          "start": 3032
        }
      ],
      "gene": "http://reg.genome.network/gene/GN001884",
      "geneNCBI_id": 1080,
      "geneSymbol": "CFTR",
      "hgvs": [
        "XM_011515753.1:c.2567dup"
      ],
      "proteinEffect": {
        "hgvs": "XP_011514055.1:p.Val857GlyfsTer?",
        "hgvsWellDefined": "XP_011514055.1:p.[Val857_Val863delinsGlyAlaTyrSerAsnHis;Lys865_Ser874delinsValGluAsnPheThrProGlnAsn;Leu876_Met880delinsThrPheCysSerSer;Leu883delinsTyrVal;Thr885delinsProGlnHisVal]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS082964"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 3950,
          "referenceAllele": "",
          "start": 3950
        }
      ],
      "gene": "http://reg.genome.network/gene/GN001884",
      "geneNCBI_id": 1080,
      "geneSymbol": "CFTR",
      "hgvs": [
        "XM_011515754.1:c.2567dup"
      ],
      "proteinEffect": {
        "hgvs": "XP_011514056.1:p.Val857GlyfsTer?",
        "hgvsWellDefined": "XP_011514056.1:p.[Val857_Val863delinsGlyAlaTyrSerAsnHis;Lys865_Ser874delinsValGluAsnPheThrProGlnAsn;Leu876_Met880delinsThrPheCysSerSer;Leu883delinsTyrVal;Thr885delinsProGlnHisVal]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS082965"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 2880,
          "referenceAllele": "",
          "start": 2880
        }
      ],
      "gene": "http://reg.genome.network/gene/GN001884",
      "geneNCBI_id": 1080,
      "geneSymbol": "CFTR",
      "hgvs": [
        "NM_000492.4:c.2810dup"
      ],
      "proteinEffect": {
        "hgvs": "NP_000483.3:p.Val938GlyfsTer?",
        "hgvsWellDefined": "NP_000483.3:p.[Val938_Val944delinsGlyAlaTyrSerAsnHis;Lys946_Ser955delinsValGluAsnPheThrProGlnAsn;Leu957_Met961delinsThrPheCysSerSer;Leu964delinsTyrVal;Thr966delinsProGlnHisVal]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS674867",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000003084.11:c.2810dup"
          },
          "RefSeq": {
            "hgvs": "NM_000492.4:c.2810dup"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000003084.6:p.Val938GlyfsTer?"
          },
          "RefSeq": {
            "hgvs": "NP_000483.3:p.Val938GlyfsTer?"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}