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          "allele": "C",
          "end": 578,
          "endIntronDirection": "-",
          "endIntronOffset": 236,
          "referenceAllele": "A",
          "start": 578,
          "startIntronDirection": "-",
          "startIntronOffset": 237
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002638",
      "geneNCBI_id": 1577,
      "geneSymbol": "CYP3A5",
      "hgvs": [
        "NM_001291830.2:c.189-237A>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_001278759.1:n.189-237A>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS682874"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 686,
          "endIntronDirection": "-",
          "endIntronOffset": 0,
          "referenceAllele": "A",
          "start": 686,
          "startIntronDirection": "-",
          "startIntronOffset": 1
        }
      ],
      "gene": "http://reg.genome.network/gene/GN002638",
      "geneNCBI_id": 1577,
      "geneSymbol": "CYP3A5",
      "hgvs": [
        "NR_033807.3:n.687-1A>C"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS702171"
    }
  ],
  "type": "nucleotide"
}