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        "hgvsWellDefined": "XP_016877114.1:p.Arg360_Lys398delinsLysLysGluIleGluGluSerLysGluProGlyValGluAspThrGluTrpSerAsnThrGlnThrGluGluAlaIleGlnThrArgSerArgThrArgLysArgValGlnLysTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS572775"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 1019,
          "referenceAllele": "C",
          "start": 1018
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012718",
      "geneNCBI_id": 7443,
      "geneSymbol": "VRK1",
      "hgvs": [
        "XR_001750539.2:n.1019C>T"
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS597768"
    },
    {
      "@id": "http://reg.genome.network/allele/PA248459",
      "coordinates": [
        {
          "allele": "T",
          "end": 1143,
          "referenceAllele": "C",
          "start": 1142
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012718",
      "geneNCBI_id": 7443,
      "geneSymbol": "VRK1",
      "hgvs": [
        "NM_003384.3:c.1072C>T"
      ],
      "proteinEffect": {
        "hgvs": "NP_003375.1:p.Arg358Ter",
        "hgvsWellDefined": "NP_003375.1:p.Arg358_Lys396delinsLysLysGluIleGluGluSerLysGluProGlyValGluAspThrGluTrpSerAsnThrGlnThrGluGluAlaIleGlnThrArgSerArgThrArgLysArgValGlnLysTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS666018",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000216639.8:c.1072C>T"
          },
          "RefSeq": {
            "hgvs": "NM_003384.3:c.1072C>T"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000216639.3:p.Arg358Ter"
          },
          "RefSeq": {
            "hgvs": "NP_003375.1:p.Arg358Ter"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}