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      "proteinEffect": {
        "hgvs": "NP_001333152.1:n.203+433G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS517396"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 328,
          "endIntronDirection": "+",
          "endIntronOffset": 433,
          "referenceAllele": "G",
          "start": 328,
          "startIntronDirection": "+",
          "startIntronOffset": 432
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006009",
      "geneNCBI_id": 3560,
      "geneSymbol": "IL2RB",
      "hgvs": [
        "NM_000878.5:c.203+433G>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_000869.1:n.203+433G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662622",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000216223.10:c.203+433G>C"
          },
          "RefSeq": {
            "hgvs": "NM_000878.5:c.203+433G>C"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000216223.5:n.203+433G>C"
          },
          "RefSeq": {
            "hgvs": "NP_000869.1:n.203+433G>C"
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 335,
          "endIntronDirection": "+",
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          "referenceAllele": "G",
          "start": 335,
          "startIntronDirection": "+",
          "startIntronOffset": 432
        }
      ],
      "gene": "http://reg.genome.network/gene/GN006009",
      "geneNCBI_id": 3560,
      "geneSymbol": "IL2RB",
      "hgvs": [
        "NM_001346223.2:c.203+433G>C"
      ],
      "proteinEffect": {
        "hgvs": "NP_001333152.1:n.203+433G>C"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS687263"
    }
  ],
  "type": "nucleotide"
}