{ "@context": "http://reg.genome.network/schema/allele.jsonld", "@id": "http://reg.genome.network/allele/CA2305058107", "communityStandardTitle": [ "NM_001083962.2(TCF4):c.500-1G=" ], "externalRecords": { "dbSNP": [ { "@id": "http://www.ncbi.nlm.nih.gov/snp/1057518864", "rs": 1057518864 } ] }, "genomicAlleles": [ { "chromosome": "18", "coordinates": [ { "allele": "C", "end": 55350409, "referenceAllele": "C", "start": 55350408 } ], "hgvs": [ "NC_000018.10:g.55350409C=", "CM000680.2:g.55350409C=" ], "referenceGenome": "GRCh38", "referenceSequence": "http://reg.genome.network/refseq/RS000066" }, { "chromosome": "18", "coordinates": [ { "allele": "C", "end": 53017640, "referenceAllele": "C", "start": 53017639 } ], "hgvs": [ "NC_000018.9:g.53017640C=", "CM000680.1:g.53017640C=" ], "referenceGenome": "GRCh37", "referenceSequence": "http://reg.genome.network/refseq/RS000042" }, { "chromosome": "18", "coordinates": [ { "allele": "C", "end": 51168638, "referenceAllele": "C", "start": 51168637 } ], "hgvs": [ "NC_000018.8:g.51168638C=" ], "referenceGenome": "NCBI36", "referenceSequence": "http://reg.genome.network/refseq/RS000018" }, { "coordinates": [ { "allele": "G", "end": 243221, "referenceAllele": "G", "start": 243220 } ], "hgvs": [ "NG_011716.1:g.243221G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS001922" }, { "coordinates": [ { "allele": "G", "end": 290585, "referenceAllele": "G", "start": 290584 } ], "hgvs": [ "NG_011716.2:g.290585G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS616147" } ], "transcriptAlleles": [ { "coordinates": [ { "allele": "G", "end": 674, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 674, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000354452.8:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000346440.3:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS748567", "MANE": { "maneVersion": "1.3", "maneStatus": "MANE Select", "nucleotide": { "Ensembl": { "hgvs": "ENST00000354452.8:c.500-1G=" }, "RefSeq": { "hgvs": "NM_001083962.2:c.500-1G=" } }, "protein": { "Ensembl": { "hgvs": "ENSP00000346440.3:n.500-1G=" }, "RefSeq": { "hgvs": "NP_001077431.1:n.500-1G=" } } } }, { "coordinates": [ { "allele": "G", "end": 708, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 708, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000635822.2:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000490451.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS762662" }, { "coordinates": [ { "allele": "G", "end": 179, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 179, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000635990.2:n.180-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS762789" }, { "coordinates": [ { "allele": "G", "end": 1125, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1125, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000636400.2:c.428-1G=" ], "proteinEffect": { "hgvs": "ENSP00000490006.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS763085" }, { "coordinates": [ { "allele": "G", "end": 1066, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1066, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000636751.2:c.*208-1G=" ], "proteinEffect": { "hgvs": "ENSP00000489783.1:n.*208-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS763352" }, { "coordinates": [ { "allele": "G", "end": 423, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 423, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000636822.2:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000490883.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS763407" }, { "coordinates": [ { "allele": "G", "end": 678, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 678, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000637115.2:c.*390-1G=" ], "proteinEffect": { "hgvs": "ENSP00000490234.1:n.*390-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS763626" }, { "coordinates": [ { "allele": "G", "end": 566, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 566, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000637239.2:n.567-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS763719" }, { "coordinates": [ { "allele": "G", "end": 193, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 193, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000637250.2:n.194-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS763727" }, { "coordinates": [ { "allele": "G", "end": 732, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 732, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000638154.3:c.530-1G=" ], "proteinEffect": { "hgvs": "ENSP00000490625.2:n.530-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS764384" }, { "coordinates": [ { "allele": "G", "end": 359, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 359, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000643689.1:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000494380.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS767412" }, { "coordinates": [ { "allele": "G", "end": 392, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 392, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000674764.1:c.*111-1G=" ], "proteinEffect": { "hgvs": "ENSP00000502213.1:n.*111-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS774681" }, { "coordinates": [ { "allele": "G", "end": 239, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 239, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000675707.1:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000501758.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS775490" }, { "coordinates": [ { "allele": "G", "end": 714, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 714, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000354452.7:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000346440.3:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS263131" }, { "coordinates": [ { "allele": "G", "end": 1111, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1111, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000356073.8:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000348374.4:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS263636" }, { "coordinates": [ { "allele": "G", "end": 935, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 935, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000398339.5:c.806-1G=" ], "proteinEffect": { "hgvs": "ENSP00000381382.1:n.806-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS278231" }, { "coordinates": [ { "allele": "G", "end": 967, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 967, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000537578.5:c.428-1G=" ], "proteinEffect": { "hgvs": "ENSP00000440731.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS360846" }, { "coordinates": [ { "allele": "G", "end": 305, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 305, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000537856.7:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000439827.2:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS360997" }, { "coordinates": [ { "allele": "G", "end": 722, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 722, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000540999.5:c.428-1G=" ], "proteinEffect": { "hgvs": "ENSP00000445202.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS362707" }, { "coordinates": [ { "allele": "G", "end": 548, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 548, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000543082.5:c.374-1G=" ], "proteinEffect": { "hgvs": "ENSP00000439656.1:n.374-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS363812" }, { "coordinates": [ { "allele": "G", "end": 567, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 567, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000544241.6:c.287-1G=" ], "proteinEffect": { "hgvs": "ENSP00000441562.2:n.287-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS364455" }, { "coordinates": [ { "allele": "G", "end": 508, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 508, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000561992.5:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455179.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS376488" }, { "coordinates": [ { "allele": "G", "end": 655, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 655, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000562030.3:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000456220.2:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS376512" }, { "coordinates": [ { "allele": "G", "end": 220, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 220, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000562607.5:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455071.2:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS376899" }, { "coordinates": [ { "allele": "G", "end": 154, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 154, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000562638.5:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000456802.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS376919" }, { "coordinates": [ { "allele": "G", "end": 590, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 590, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000562680.5:n.591-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS376940" }, { "coordinates": [ { "allele": "G", "end": 354, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 354, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000563686.5:n.355-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS377592" }, { "coordinates": [ { "allele": "G", "end": 848, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 848, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000563824.5:c.428-1G=" ], "proteinEffect": { "hgvs": "ENSP00000457113.2:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS377672" }, { "coordinates": [ { "allele": "G", "end": 556, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 556, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000563888.6:c.425-1G=" ], "proteinEffect": { "hgvs": "ENSP00000457747.3:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS377716" }, { "coordinates": [ { "allele": "G", "end": 286, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 286, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000564228.5:c.287-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455261.1:n.287-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS377953" }, { "coordinates": [ { "allele": "G", "end": 1062, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1062, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000564403.6:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000457263.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS378069" }, { "coordinates": [ { "allele": "G", "end": 696, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 696, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000564999.5:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000457649.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS378480" }, { "coordinates": [ { "allele": "G", "end": 778, "endIntronDirection": "+", "endIntronOffset": 53045, "referenceAllele": "G", "start": 778, "startIntronDirection": "+", "startIntronOffset": 53044 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000565018.6:c.297+53045G=" ], "proteinEffect": { "hgvs": "ENSP00000455984.2:n.297+53045G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS378492" }, { "coordinates": [ { "allele": "G", "end": 298, "endIntronDirection": "+", "endIntronOffset": 53045, "referenceAllele": "G", "start": 298, "startIntronDirection": "+", "startIntronOffset": 53044 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000565580.3:n.298+53045G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS378847" }, { "coordinates": [ { "allele": "G", "end": 603, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 603, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000565908.6:c.428-1G=" ], "proteinEffect": { "hgvs": "ENSP00000454584.2:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS379055" }, { "coordinates": [ { "allele": "G", "end": 537, "endIntronDirection": "+", "endIntronOffset": 53045, "referenceAllele": "G", "start": 537, "startIntronDirection": "+", "startIntronOffset": 53044 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000566279.5:c.369+53045G=" ], "proteinEffect": { "hgvs": "ENSP00000456125.1:n.369+53045G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS379326" }, { "coordinates": [ { "allele": "G", "end": 493, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 493, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000566286.5:c.494-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455418.2:n.494-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS379331" }, { "coordinates": [ { "allele": "G", "end": 179, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 179, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000566376.3:n.180-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS379393" }, { "coordinates": [ { "allele": "G", "end": 566, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 566, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000566514.5:c.461-1G=" ], "proteinEffect": { "hgvs": "ENSP00000456983.2:n.461-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS379494" }, { "coordinates": [ { "allele": "G", "end": 359, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 359, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000566777.5:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000457245.2:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS379677" }, { "coordinates": [ { "allele": "G", "end": 369, "endIntronDirection": "+", "endIntronOffset": 53045, "referenceAllele": "G", "start": 369, "startIntronDirection": "+", "startIntronOffset": 53044 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000567880.5:c.369+53045G=" ], "proteinEffect": { "hgvs": "ENSP00000454366.1:n.369+53045G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS380404" }, { "coordinates": [ { "allele": "G", "end": 517, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 517, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000568147.5:c.464-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455163.2:n.464-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS380577" }, { "coordinates": [ { "allele": "G", "end": 540, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 540, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000568169.5:c.512-1G=" ], "proteinEffect": { "hgvs": "ENSP00000457392.1:n.512-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS380591" }, { "coordinates": [ { "allele": "G", "end": 334, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 334, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000568186.5:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000458122.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS380603" }, { "coordinates": [ { "allele": "G", "end": 525, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 525, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000568673.5:c.428-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455135.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS380953" }, { "coordinates": [ { "allele": "G", "end": 934, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 934, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000568740.5:c.425-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455346.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS380991" }, { "coordinates": [ { "allele": "G", "end": 182, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 182, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000569012.5:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000455304.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS381177" }, { "coordinates": [ { "allele": "G", "end": 316, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 316, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000570177.6:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000454647.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS381959" }, { "coordinates": [ { "allele": "G", "end": 312, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 312, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000590810.5:c.146-1G=" ], "proteinEffect": { "hgvs": "ENSP00000468277.2:n.146-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS392451" }, { "coordinates": [ { "allele": "G", "end": 981, "endIntronDirection": "+", "endIntronOffset": 53045, "referenceAllele": "G", "start": 981, "startIntronDirection": "+", "startIntronOffset": 53044 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000616053.4:c.297+53045G=" ], "proteinEffect": { "hgvs": "ENSP00000478549.1:n.297+53045G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS402894" }, { "coordinates": [ { "allele": "G", "end": 359, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 359, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000625849.2:n.360-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS406633" }, { "coordinates": [ { "allele": "G", "end": 310, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 310, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000625925.2:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000487413.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS406647" }, { "coordinates": [ { "allele": "G", "end": 466, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 466, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000626425.2:c.425-1G=" ], "proteinEffect": { "hgvs": "ENSP00000486111.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS406738" }, { "coordinates": [ { "allele": "G", "end": 246, "endIntronDirection": "+", "endIntronOffset": 53045, "referenceAllele": "G", "start": 246, "startIntronDirection": "+", "startIntronOffset": 53044 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000626584.2:c.-100+53045G=" ], "proteinEffect": { "hgvs": "ENSP00000486072.1:n.-100+53045G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS406758" }, { "coordinates": [ { "allele": "G", "end": 669, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 669, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000626595.2:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000487415.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS406760" }, { "coordinates": [ { "allele": "G", "end": 473, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 473, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000627136.2:n.474-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS406843" }, { "coordinates": [ { "allele": "G", "end": 697, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 697, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000627685.2:c.428-1G=" ], "proteinEffect": { "hgvs": "ENSP00000487171.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS406937" }, { "coordinates": [ { "allele": "G", "end": 764, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 764, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000628078.2:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000486909.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS406988" }, { "coordinates": [ { "allele": "G", "end": 261, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 261, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000628636.2:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000485755.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS407083" }, { "coordinates": [ { "allele": "G", "end": 207, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 207, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000629343.2:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000486148.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS407207" }, { "coordinates": [ { "allele": "G", "end": 1030, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1030, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000629387.2:c.500-1G=" ], "proteinEffect": { "hgvs": "ENSP00000486670.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS407217" }, { "coordinates": [ { "allele": "G", "end": 279, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 279, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000630268.2:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000486405.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS407344" }, { "coordinates": [ { "allele": "G", "end": 397, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 397, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000630319.2:c.269-1G=" ], "proteinEffect": { "hgvs": "ENSP00000486215.1:n.269-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS407355" }, { "coordinates": [ { "allele": "G", "end": 554, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 554, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000630712.2:c.110-1G=" ], "proteinEffect": { "hgvs": "ENSP00000487419.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS407407" }, { "coordinates": [ { "allele": "G", "end": 339, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 339, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000630828.2:c.290-1G=" ], "proteinEffect": { "hgvs": "ENSP00000486974.1:n.290-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS407428" }, { "coordinates": [ { "allele": "G", "end": 298, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 298, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "ENST00000631043.2:n.299-1G=" ], "referenceSequence": "http://reg.genome.network/refseq/RS407465" }, { "coordinates": [ { "allele": "G", "end": 1111, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1111, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001083962.1:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001077431.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS010431" }, { "coordinates": [ { "allele": "G", "end": 901, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 901, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243226.2:c.806-1G=" ], "proteinEffect": { "hgvs": "NP_001230155.2:n.806-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS018449" }, { "coordinates": [ { "allele": "G", "end": 945, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 945, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243227.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001230156.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS018450" }, { "coordinates": [ { "allele": "G", "end": 1037, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1037, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243228.1:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001230157.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS018451" }, { "coordinates": [ { "allele": "G", "end": 587, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 587, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243230.1:c.494-1G=" ], "proteinEffect": { "hgvs": "NP_001230159.1:n.494-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS018452" }, { "coordinates": [ { "allele": "G", "end": 545, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 545, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243231.1:c.374-1G=" ], "proteinEffect": { "hgvs": "NP_001230160.1:n.374-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS018453" }, { "coordinates": [ { "allele": "G", "end": 567, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 567, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243232.1:c.287-1G=" ], "proteinEffect": { "hgvs": "NP_001230161.1:n.287-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS018454" }, { "coordinates": [ { "allele": "G", "end": 508, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 508, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243233.1:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001230162.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS018455" }, { "coordinates": [ { "allele": "G", "end": 736, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 736, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001306207.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001293136.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS026030" }, { "coordinates": [ { "allele": "G", "end": 567, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 567, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001306208.1:c.287-1G=" ], "proteinEffect": { "hgvs": "NP_001293137.1:n.287-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS026031" }, { "coordinates": [ { "allele": "G", "end": 1111, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1111, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_003199.2:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_003190.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS028464" }, { "coordinates": [ { "allele": "G", "end": 751, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 751, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266739.3:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_005266796.2:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065157" }, { "coordinates": [ { "allele": "G", "end": 711, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 711, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266741.3:c.497-1G=" ], "proteinEffect": { "hgvs": "XP_005266798.1:n.497-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065158" }, { "coordinates": [ { "allele": "G", "end": 569, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 569, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266743.3:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_005266800.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065159" }, { "coordinates": [ { "allele": "G", "end": 692, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 692, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266744.3:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_005266801.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065160" }, { "coordinates": [ { "allele": "G", "end": 554, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 554, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266745.3:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_005266802.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065161" }, { "coordinates": [ { "allele": "G", "end": 548, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 548, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266747.3:c.374-1G=" ], "proteinEffect": { "hgvs": "XP_005266804.1:n.374-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065162" }, { "coordinates": [ { "allele": "G", "end": 339, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 339, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266749.3:c.290-1G=" ], "proteinEffect": { "hgvs": "XP_005266806.1:n.290-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065163" }, { "coordinates": [ { "allele": "G", "end": 503, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 503, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266752.3:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_005266809.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065164" }, { "coordinates": [ { "allele": "G", "end": 333, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 333, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266754.3:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_005266811.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065165" }, { "coordinates": [ { "allele": "G", "end": 306, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 306, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266755.3:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_005266812.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS065166" }, { "coordinates": [ { "allele": "G", "end": 1034, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1034, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722536.2:c.500-1G=" ], "proteinEffect": { "hgvs": "XP_006722599.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS074600" }, { "coordinates": [ { "allele": "G", "end": 667, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 667, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722537.2:c.500-1G=" ], "proteinEffect": { "hgvs": "XP_006722600.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS074601" }, { "coordinates": [ { "allele": "G", "end": 689, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 689, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722538.2:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_006722601.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS074602" }, { "coordinates": [ { "allele": "G", "end": 238, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 238, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722539.2:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_006722602.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS074603" }, { "coordinates": [ { "allele": "G", "end": 238, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 238, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722540.2:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_006722603.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS074604" }, { "coordinates": [ { "allele": "G", "end": 862, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 862, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526154.1:c.803-1G=" ], "proteinEffect": { "hgvs": "XP_011524456.1:n.803-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093261" }, { "coordinates": [ { "allele": "G", "end": 865, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 865, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526155.1:c.806-1G=" ], "proteinEffect": { "hgvs": "XP_011524457.1:n.806-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093262" }, { "coordinates": [ { "allele": "G", "end": 865, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 865, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526156.1:c.806-1G=" ], "proteinEffect": { "hgvs": "XP_011524458.1:n.806-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093263" }, { "coordinates": [ { "allele": "G", "end": 862, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 862, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526157.1:c.803-1G=" ], "proteinEffect": { "hgvs": "XP_011524459.1:n.803-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093264" }, { "coordinates": [ { "allele": "G", "end": 569, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 569, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526158.1:c.494-1G=" ], "proteinEffect": { "hgvs": "XP_011524460.1:n.494-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093265" }, { "coordinates": [ { "allele": "G", "end": 354, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 354, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526159.1:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_011524461.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093266" }, { "coordinates": [ { "allele": "G", "end": 650, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 650, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526160.1:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_011524462.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093267" }, { "coordinates": [ { "allele": "G", "end": 311, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 311, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526161.1:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_011524463.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093268" }, { "coordinates": [ { "allele": "G", "end": 328, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 328, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526162.1:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_011524464.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093269" }, { "coordinates": [ { "allele": "G", "end": 274, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 274, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526163.1:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_011524465.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093270" }, { "coordinates": [ { "allele": "G", "end": 311, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 311, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_011526164.1:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_011524466.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS093271" }, { "coordinates": [ { "allele": "G", "end": 1111, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1111, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001330604.2:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001317533.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS516949" }, { "coordinates": [ { "allele": "G", "end": 528, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 528, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001330605.2:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001317534.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS516950" }, { "coordinates": [ { "allele": "G", "end": 545, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 545, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348211.1:c.374-1G=" ], "proteinEffect": { "hgvs": "NP_001335140.1:n.374-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS518066" }, { "coordinates": [ { "allele": "G", "end": 493, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 493, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348212.1:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001335141.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS518067" }, { "coordinates": [ { "allele": "G", "end": 496, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 496, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348213.1:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001335142.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS518068" }, { "coordinates": [ { "allele": "G", "end": 736, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 736, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348217.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001335146.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS518072" }, { "coordinates": [ { "allele": "G", "end": 574, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 574, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348218.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001335147.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS518073" }, { "coordinates": [ { "allele": "G", "end": 574, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 574, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348219.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001335148.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS518074" }, { "coordinates": [ { "allele": "G", "end": 733, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 733, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348220.1:c.425-1G=" ], "proteinEffect": { "hgvs": "NP_001335149.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS518075" }, { "coordinates": [ { "allele": "G", "end": 751, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 751, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266739.4:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_005266796.2:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS536280" }, { "coordinates": [ { "allele": "G", "end": 711, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 711, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266741.4:c.497-1G=" ], "proteinEffect": { "hgvs": "XP_005266798.1:n.497-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS536281" }, { "coordinates": [ { "allele": "G", "end": 555, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 555, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266745.4:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_005266802.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS536282" }, { "coordinates": [ { "allele": "G", "end": 339, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 339, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266749.4:c.290-1G=" ], "proteinEffect": { "hgvs": "XP_005266806.1:n.290-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS536283" }, { "coordinates": [ { "allele": "G", "end": 910, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 910, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266752.5:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_005266809.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS536284" }, { "coordinates": [ { "allele": "G", "end": 367, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 367, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_005266755.5:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_005266812.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS536285" }, { "coordinates": [ { "allele": "G", "end": 1028, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1028, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722536.3:c.500-1G=" ], "proteinEffect": { "hgvs": "XP_006722599.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS540562" }, { "coordinates": [ { "allele": "G", "end": 667, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 667, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722537.3:c.500-1G=" ], "proteinEffect": { "hgvs": "XP_006722600.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS540563" }, { "coordinates": [ { "allele": "G", "end": 689, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 689, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_006722538.3:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_006722601.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS540564" }, { "coordinates": [ { "allele": "G", "end": 748, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 748, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025934.2:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_016881423.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576166" }, { "coordinates": [ { "allele": "G", "end": 751, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 751, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025935.2:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_016881424.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576167" }, { "coordinates": [ { "allele": "G", "end": 751, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 751, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025936.2:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_016881425.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576168" }, { "coordinates": [ { "allele": "G", "end": 505, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 505, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025937.2:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_016881426.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576169" }, { "coordinates": [ { "allele": "G", "end": 664, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 664, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025938.2:c.497-1G=" ], "proteinEffect": { "hgvs": "XP_016881427.1:n.497-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576170" }, { "coordinates": [ { "allele": "G", "end": 1028, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1028, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025940.2:c.500-1G=" ], "proteinEffect": { "hgvs": "XP_016881429.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576171" }, { "coordinates": [ { "allele": "G", "end": 667, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 667, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025941.2:c.500-1G=" ], "proteinEffect": { "hgvs": "XP_016881430.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576172" }, { "coordinates": [ { "allele": "G", "end": 711, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 711, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025942.2:c.497-1G=" ], "proteinEffect": { "hgvs": "XP_016881431.1:n.497-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576173" }, { "coordinates": [ { "allele": "G", "end": 714, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 714, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025943.2:c.500-1G=" ], "proteinEffect": { "hgvs": "XP_016881432.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576174" }, { "coordinates": [ { "allele": "G", "end": 973, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 973, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025944.2:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_016881433.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576175" }, { "coordinates": [ { "allele": "G", "end": 976, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 976, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025945.2:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_016881434.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576176" }, { "coordinates": [ { "allele": "G", "end": 986, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 986, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025946.2:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_016881435.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576177" }, { "coordinates": [ { "allele": "G", "end": 973, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 973, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025948.2:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_016881437.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576178" }, { "coordinates": [ { "allele": "G", "end": 973, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 973, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025950.2:c.425-1G=" ], "proteinEffect": { "hgvs": "XP_016881439.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576179" }, { "coordinates": [ { "allele": "G", "end": 548, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 548, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025951.2:c.374-1G=" ], "proteinEffect": { "hgvs": "XP_016881440.1:n.374-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576180" }, { "coordinates": [ { "allele": "G", "end": 562, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 562, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025952.2:c.287-1G=" ], "proteinEffect": { "hgvs": "XP_016881441.1:n.287-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576181" }, { "coordinates": [ { "allele": "G", "end": 339, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 339, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025953.2:c.290-1G=" ], "proteinEffect": { "hgvs": "XP_016881442.1:n.290-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576182" }, { "coordinates": [ { "allele": "G", "end": 923, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 923, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025954.2:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_016881443.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576183" }, { "coordinates": [ { "allele": "G", "end": 333, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 333, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_017025956.2:c.110-1G=" ], "proteinEffect": { "hgvs": "XP_016881445.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS576184" }, { "coordinates": [ { "allele": "G", "end": 569, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 569, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_024451240.1:c.428-1G=" ], "proteinEffect": { "hgvs": "XP_024307008.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS584759" }, { "coordinates": [ { "allele": "G", "end": 365, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 365, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "XM_024451241.1:c.263-1G=" ], "proteinEffect": { "hgvs": "XP_024307009.1:n.263-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS584760" }, { "coordinates": [ { "allele": "G", "end": 674, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 674, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001083962.2:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001077431.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS676369", "MANE": { "maneVersion": "1.3", "maneStatus": "MANE Select", "nucleotide": { "Ensembl": { "hgvs": "ENST00000354452.8:c.500-1G=" }, "RefSeq": { "hgvs": "NM_001083962.2:c.500-1G=" } }, "protein": { "Ensembl": { "hgvs": "ENSP00000346440.3:n.500-1G=" }, "RefSeq": { "hgvs": "NP_001077431.1:n.500-1G=" } } } }, { "coordinates": [ { "allele": "G", "end": 865, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 865, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243226.3:c.806-1G=" ], "proteinEffect": { "hgvs": "NP_001230155.2:n.806-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS680199" }, { "coordinates": [ { "allele": "G", "end": 942, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 942, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243227.2:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001230156.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS680200" }, { "coordinates": [ { "allele": "G", "end": 1034, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1034, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243228.2:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001230157.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS680201" }, { "coordinates": [ { "allele": "G", "end": 548, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 548, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243231.2:c.374-1G=" ], "proteinEffect": { "hgvs": "NP_001230160.1:n.374-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS680202" }, { "coordinates": [ { "allele": "G", "end": 313, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 313, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243233.2:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001230162.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS680203" }, { "coordinates": [ { "allele": "G", "end": 674, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 674, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001330604.3:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001317533.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS687027" }, { "coordinates": [ { "allele": "G", "end": 239, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 239, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001330605.3:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001317534.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS687028" }, { "coordinates": [ { "allele": "G", "end": 548, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 548, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348211.2:c.374-1G=" ], "proteinEffect": { "hgvs": "NP_001335140.1:n.374-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS687607" }, { "coordinates": [ { "allele": "G", "end": 298, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 298, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348212.2:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001335141.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS687608" }, { "coordinates": [ { "allele": "G", "end": 301, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 301, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348213.2:c.110-1G=" ], "proteinEffect": { "hgvs": "NP_001335142.1:n.110-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS687609" }, { "coordinates": [ { "allele": "G", "end": 577, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 577, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348218.2:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001335147.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS687613" }, { "coordinates": [ { "allele": "G", "end": 577, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 577, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001348219.2:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001335148.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS687614" }, { "coordinates": [ { "allele": "G", "end": 1034, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1034, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369567.1:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001356496.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691778" }, { "coordinates": [ { "allele": "G", "end": 667, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 667, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369568.1:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001356497.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691779" }, { "coordinates": [ { "allele": "G", "end": 664, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 664, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369569.1:c.497-1G=" ], "proteinEffect": { "hgvs": "NP_001356498.1:n.497-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691780" }, { "coordinates": [ { "allele": "G", "end": 671, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 671, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369570.1:c.497-1G=" ], "proteinEffect": { "hgvs": "NP_001356499.1:n.497-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691781" }, { "coordinates": [ { "allele": "G", "end": 1034, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 1034, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369571.1:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001356500.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691782" }, { "coordinates": [ { "allele": "G", "end": 667, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 667, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369572.1:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001356501.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691783" }, { "coordinates": [ { "allele": "G", "end": 671, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 671, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369573.1:c.497-1G=" ], "proteinEffect": { "hgvs": "NP_001356502.1:n.497-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691784" }, { "coordinates": [ { "allele": "G", "end": 674, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 674, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369574.1:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_001356503.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691785" }, { "coordinates": [ { "allele": "G", "end": 582, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 582, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369575.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001356504.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691786" }, { "coordinates": [ { "allele": "G", "end": 939, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 939, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369576.1:c.425-1G=" ], "proteinEffect": { "hgvs": "NP_001356505.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691787" }, { "coordinates": [ { "allele": "G", "end": 942, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 942, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369577.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001356506.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691788" }, { "coordinates": [ { "allele": "G", "end": 579, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 579, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369578.1:c.425-1G=" ], "proteinEffect": { "hgvs": "NP_001356507.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691789" }, { "coordinates": [ { "allele": "G", "end": 582, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 582, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369579.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001356508.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691790" }, { "coordinates": [ { "allele": "G", "end": 577, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 577, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369580.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001356509.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691791" }, { "coordinates": [ { "allele": "G", "end": 574, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 574, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369581.1:c.425-1G=" ], "proteinEffect": { "hgvs": "NP_001356510.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691792" }, { "coordinates": [ { "allele": "G", "end": 942, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 942, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369582.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001356511.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691793" }, { "coordinates": [ { "allele": "G", "end": 582, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 582, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369583.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001356512.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691794" }, { "coordinates": [ { "allele": "G", "end": 939, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 939, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369584.1:c.425-1G=" ], "proteinEffect": { "hgvs": "NP_001356513.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691795" }, { "coordinates": [ { "allele": "G", "end": 579, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 579, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369585.1:c.425-1G=" ], "proteinEffect": { "hgvs": "NP_001356514.1:n.425-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691796" }, { "coordinates": [ { "allele": "G", "end": 942, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 942, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001369586.1:c.428-1G=" ], "proteinEffect": { "hgvs": "NP_001356515.1:n.428-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS691797" }, { "coordinates": [ { "allele": "G", "end": 674, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 674, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_003199.3:c.500-1G=" ], "proteinEffect": { "hgvs": "NP_003190.1:n.500-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS695755" }, { "coordinates": [ { "allele": "G", "end": 575, "endIntronDirection": "-", "endIntronOffset": 0, "referenceAllele": "G", "start": 575, "startIntronDirection": "-", "startIntronOffset": 1 } ], "gene": "http://reg.genome.network/gene/GN011634", "geneNCBI_id": 6925, "geneSymbol": "TCF4", "hgvs": [ "NM_001243230.2:c.494-1G=" ], "proteinEffect": { "hgvs": "NP_001230159.1:n.494-1G=" }, "referenceSequence": "http://reg.genome.network/refseq/RS714455" } ], "type": "nucleotide" }