{
  "@context": "http://reg.genome.network/schema/allele.jsonld",
  "@id": "http://reg.genome.network/allele/CA2181323828",
  "communityStandardTitle": [
    "NM_134261.3(RORA):c.196+11805G="
  ],
  "externalRecords": {
    "dbSNP": [
      {
        "@id": "http://www.ncbi.nlm.nih.gov/snp/339972",
        "rs": 339972
      }
    ]
  },
  "genomicAlleles": [
    {
      "chromosome": "15",
      "coordinates": [
        {
          "allele": "C",
          "end": 60666852,
          "referenceAllele": "C",
          "start": 60666851
        }
      ],
      "hgvs": [
        "NC_000015.10:g.60666852C=",
        "CM000677.2:g.60666852C="
      ],
      "referenceGenome": "GRCh38",
      "referenceSequence": "http://reg.genome.network/refseq/RS000063"
    },
    {
      "chromosome": "15",
      "coordinates": [
        {
          "allele": "C",
          "end": 60959051,
          "referenceAllele": "C",
          "start": 60959050
        }
      ],
      "hgvs": [
        "NC_000015.9:g.60959051C=",
        "CM000677.1:g.60959051C="
      ],
      "referenceGenome": "GRCh37",
      "referenceSequence": "http://reg.genome.network/refseq/RS000039"
    },
    {
      "chromosome": "15",
      "coordinates": [
        {
          "allele": "C",
          "end": 58746343,
          "referenceAllele": "C",
          "start": 58746342
        }
      ],
      "hgvs": [
        "NC_000015.8:g.58746343C="
      ],
      "referenceGenome": "NCBI36",
      "referenceSequence": "http://reg.genome.network/refseq/RS000015"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 567452,
          "referenceAllele": "G",
          "start": 567451
        }
      ],
      "hgvs": [
        "NG_029246.1:g.567452G="
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS004341"
    }
  ],
  "transcriptAlleles": [
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 280,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 280,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "ENST00000335670.11:c.196+11805G="
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000335087.6:n.196+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS747514",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000335670.11:c.196+11805G="
          },
          "RefSeq": {
            "hgvs": "NM_134261.3:c.196+11805G="
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000335087.6:n.196+11805G="
          },
          "RefSeq": {
            "hgvs": "NP_599023.1:n.196+11805G="
          }
        }
      }
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 297,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 297,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "ENST00000335670.10:c.196+11805G="
      ],
      "proteinEffect": {
        "hgvs": "ENSP00000335087.6:n.196+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS260170"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 193,
          "endIntronDirection": "+",
          "endIntronOffset": 10299,
          "referenceAllele": "G",
          "start": 193,
          "startIntronDirection": "+",
          "startIntronOffset": 10298
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "ENST00000551975.5:c.193+10299G="
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS368976"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 221,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 221,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "ENST00000557822.5:n.221+11805G="
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS373335"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 285,
          "endIntronDirection": "+",
          "endIntronOffset": 10299,
          "referenceAllele": "G",
          "start": 285,
          "startIntronDirection": "+",
          "startIntronOffset": 10298
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "ENST00000559145.1:n.285+10299G="
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS374349"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 151,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 151,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "ENST00000560004.5:n.151+11805G="
      ],
      "referenceSequence": "http://reg.genome.network/refseq/RS375023"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 281,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 281,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "NM_134261.2:c.196+11805G="
      ],
      "proteinEffect": {
        "hgvs": "NP_599023.1:n.196+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS040585"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 73,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 73,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "XM_005254584.3:c.58+11805G="
      ],
      "proteinEffect": {
        "hgvs": "XP_005254641.1:n.58+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS060676"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 151,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 151,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "XM_011521875.1:c.139+11805G="
      ],
      "proteinEffect": {
        "hgvs": "XP_011520177.1:n.139+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS089034"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 175,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 175,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "XM_011521876.1:c.64+11805G="
      ],
      "proteinEffect": {
        "hgvs": "XP_011520178.1:n.64+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS089035"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 193,
          "endIntronDirection": "+",
          "endIntronOffset": 10299,
          "referenceAllele": "G",
          "start": 193,
          "startIntronDirection": "+",
          "startIntronOffset": 10298
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "XM_011521878.1:c.-216+10299G="
      ],
      "proteinEffect": {
        "hgvs": "XP_011520180.1:n.-216+10299G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS089037"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 4742,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 4742,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "XM_005254584.5:c.58+11805G="
      ],
      "proteinEffect": {
        "hgvs": "XP_005254641.1:n.58+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS534144"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 151,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 151,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "XM_011521875.2:c.139+11805G="
      ],
      "proteinEffect": {
        "hgvs": "XP_011520177.1:n.139+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS546357"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 193,
          "endIntronDirection": "+",
          "endIntronOffset": 10299,
          "referenceAllele": "G",
          "start": 193,
          "startIntronDirection": "+",
          "startIntronOffset": 10298
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "XM_011521878.2:c.-216+10299G="
      ],
      "proteinEffect": {
        "hgvs": "XP_011520180.1:n.-216+10299G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS546359"
    },
    {
      "coordinates": [
        {
          "allele": "G",
          "end": 280,
          "endIntronDirection": "+",
          "endIntronOffset": 11805,
          "referenceAllele": "G",
          "start": 280,
          "startIntronDirection": "+",
          "startIntronOffset": 11804
        }
      ],
      "gene": "http://reg.genome.network/gene/GN010258",
      "geneNCBI_id": 6095,
      "geneSymbol": "RORA",
      "hgvs": [
        "NM_134261.3:c.196+11805G="
      ],
      "proteinEffect": {
        "hgvs": "NP_599023.1:n.196+11805G="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS671851",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000335670.11:c.196+11805G="
          },
          "RefSeq": {
            "hgvs": "NM_134261.3:c.196+11805G="
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000335087.6:n.196+11805G="
          },
          "RefSeq": {
            "hgvs": "NP_599023.1:n.196+11805G="
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}