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    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 804,
          "endIntronDirection": "-",
          "endIntronOffset": 250,
          "referenceAllele": "C",
          "start": 804,
          "startIntronDirection": "-",
          "startIntronOffset": 251
        }
      ],
      "gene": "http://reg.genome.network/gene/GN004982",
      "geneNCBI_id": 3145,
      "geneSymbol": "HMBS",
      "hgvs": [
        "NM_001258208.2:c.652-251C="
      ],
      "proteinEffect": {
        "hgvs": "NP_001245137.1:n.652-251C="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS714913"
    },
    {
      "coordinates": [
        {
          "allele": "C",
          "end": 895,
          "endIntronDirection": "-",
          "endIntronOffset": 250,
          "referenceAllele": "C",
          "start": 895,
          "startIntronDirection": "-",
          "startIntronOffset": 251
        }
      ],
      "gene": "http://reg.genome.network/gene/GN004982",
      "geneNCBI_id": 3145,
      "geneSymbol": "HMBS",
      "hgvs": [
        "NM_001258209.2:c.601-251C="
      ],
      "proteinEffect": {
        "hgvs": "NP_001245138.1:n.601-251C="
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS714914"
    }
  ],
  "type": "nucleotide"
}