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          "start": 4430
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545946.2:c.3432_3435del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544248.1:p.Leu1144PhefsTer20",
        "hgvsWellDefined": "XP_011544248.1:p.[Leu1144_Ala1151delinsPheSerValSerVal;Leu1153del;Pro1155_Val1156delinsSer;Asp1158_Gln1159del;Trp1161Leu;Phe1163_Ser1167delinsLeuThrAsnIle;Thr1169_His1172del;Ala1175del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556315"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 4250,
          "referenceAllele": "ACTT",
          "start": 4246
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545947.2:c.*61_*64del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544249.1:n.*61_*64del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556316"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3721,
          "referenceAllele": "ACTT",
          "start": 3717
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_011545948.2:c.2541_2544del"
      ],
      "proteinEffect": {
        "hgvs": "XP_011544250.1:p.Leu847PhefsTer20",
        "hgvsWellDefined": "XP_011544250.1:p.[Leu847_Ala854delinsPheSerValSerVal;Leu856del;Pro858_Val859delinsSer;Asp861_Gln862del;Trp864Leu;Phe866_Ser870delinsLeuThrAsnIle;Thr872_His875del;Ala878del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS556317"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 4162,
          "referenceAllele": "ACTT",
          "start": 4158
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023671.1:c.3195_3198del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879160.1:p.Leu1065PhefsTer20",
        "hgvsWellDefined": "XP_016879160.1:p.[Leu1065_Ala1072delinsPheSerValSerVal;Leu1074del;Pro1076_Val1077delinsSer;Asp1079_Gln1080del;Trp1082Leu;Phe1084_Ser1088delinsLeuThrAsnIle;Thr1090_His1093del;Ala1096del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574393"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3372,
          "referenceAllele": "ACTT",
          "start": 3368
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      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023672.2:c.3189_3192del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879161.1:p.Leu1063PhefsTer20",
        "hgvsWellDefined": "XP_016879161.1:p.[Leu1063_Ala1070delinsPheSerValSerVal;Leu1072del;Pro1074_Val1075delinsSer;Asp1077_Gln1078del;Trp1080Leu;Phe1082_Ser1086delinsLeuThrAsnIle;Thr1088_His1091del;Ala1094del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574394"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3460,
          "referenceAllele": "ACTT",
          "start": 3456
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "XM_017023673.2:c.*61_*64del"
      ],
      "proteinEffect": {
        "hgvs": "XP_016879162.1:n.*61_*64del"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS574395"
    },
    {
      "coordinates": [
        {
          "allele": "",
          "end": 3582,
          "referenceAllele": "ACTT",
          "start": 3578
        }
      ],
      "gene": "http://reg.genome.network/gene/GN026144",
      "geneNCBI_id": 79728,
      "geneSymbol": "PALB2",
      "hgvs": [
        "NM_024675.4:c.3426_3429del"
      ],
      "proteinEffect": {
        "hgvs": "NP_078951.2:p.Leu1142PhefsTer20",
        "hgvsWellDefined": "NP_078951.2:p.[Leu1142_Ala1149delinsPheSerValSerVal;Leu1151del;Pro1153_Val1154delinsSer;Asp1156_Gln1157del;Trp1159Leu;Phe1161_Ser1165delinsLeuThrAsnIle;Thr1167_His1170del;Ala1173del]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS698739",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000261584.9:c.3426_3429del"
          },
          "RefSeq": {
            "hgvs": "NM_024675.4:c.3426_3429del"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000261584.4:p.Leu1142PhefsTer20"
          },
          "RefSeq": {
            "hgvs": "NP_078951.2:p.Leu1142PhefsTer20"
          }
        }
      }
    }
  ],
  "type": "nucleotide"
}