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      "hgvs": [
        "XM_011523104.3:c.1005G>A"
      ],
      "proteinEffect": {
        "hgvs": "XP_011521406.1:p.Trp335Ter",
        "hgvsWellDefined": "XP_011521406.1:p.Trp336_Asp353delinsValTyrThrLeuLeuPheThrLeuAlaArgProPheThrLysSerMetAspTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS546893"
    },
    {
      "@id": "http://reg.genome.network/allele/PA645497351",
      "coordinates": [
        {
          "allele": "A",
          "end": 1130,
          "referenceAllele": "G",
          "start": 1129
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012799",
      "geneNCBI_id": 51741,
      "geneSymbol": "WWOX",
      "hgvs": [
        "NM_016373.4:c.1005G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_057457.1:p.Trp335Ter",
        "hgvsWellDefined": "NP_057457.1:p.Trp336_Gly414delinsValTyrThrLeuLeuPheThrLeuAlaArgProPheThrLysSerMetGlnGlnGlyAlaAlaThrThrValTyrCysAlaAlaValProGluLeuGluGlyLeuGlyGlyMetTyrPheAsnAsnCysCysArgCysMetProSerProGluAlaGlnSerGluGluThrAlaArgThrLeuTrpAlaLeuSerGluArgLeuIleGlnGluArgLeuGlySerGlnSerGlyTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS669107",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
            "hgvs": "ENST00000566780.6:c.1005G>A"
          },
          "RefSeq": {
            "hgvs": "NM_016373.4:c.1005G>A"
          }
        },
        "protein": {
          "Ensembl": {
            "hgvs": "ENSP00000457230.1:p.Trp335Ter"
          },
          "RefSeq": {
            "hgvs": "NP_057457.1:p.Trp335Ter"
          }
        }
      }
    },
    {
      "@id": "http://reg.genome.network/allele/PA2826816245",
      "coordinates": [
        {
          "allele": "A",
          "end": 1065,
          "referenceAllele": "G",
          "start": 1064
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012799",
      "geneNCBI_id": 51741,
      "geneSymbol": "WWOX",
      "hgvs": [
        "NM_001291997.2:c.666G>A"
      ],
      "proteinEffect": {
        "hgvs": "NP_001278926.1:p.Trp222Ter",
        "hgvsWellDefined": "NP_001278926.1:p.Trp223_Gly301delinsValTyrThrLeuLeuPheThrLeuAlaArgProPheThrLysSerMetGlnGlnGlyAlaAlaThrThrValTyrCysAlaAlaValProGluLeuGluGlyLeuGlyGlyMetTyrPheAsnAsnCysCysArgCysMetProSerProGluAlaGlnSerGluGluThrAlaArgThrLeuTrpAlaLeuSerGluArgLeuIleGlnGluArgLeuGlySerGlnSerGlyTer"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS682940"
    }
  ],
  "type": "nucleotide"
}