{
  "@context": "http://reg.genome.network/schema/allele.jsonld",
  "@id": "http://reg.genome.network/allele/CA175070359",
  "communityStandardTitle": [
    "NM_000025.3(ADRB3):c.1175_1184dup (p.Arg395SerfsTer29)"
  ],
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      {
        "@id": "http://myvariant.info/v1/variant/chr8:g.37822803_37822804insCTGGGCTGCG?assembly=hg19",
        "id": "chr8:g.37822803_37822804insCTGGGCTGCG"
      }
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      {
        "@id": "http://myvariant.info/v1/variant/chr8:g.37965285_37965286insCTGGGCTGCG?assembly=hg38",
        "id": "chr8:g.37965285_37965286insCTGGGCTGCG"
      }
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        "@id": "http://www.ncbi.nlm.nih.gov/snp/928008261",
        "rs": 928008261
      }
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        "id": "8-37822803-C-CCTGGGCTGCG",
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      }
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    "gnomAD_3": [
      {
        "@id": "http://gnomad.broadinstitute.org/variant/8-37965285-C-CCTGGGCTGCG?dataset=gnomad_r3",
        "id": "8-37965285-C-CCTGGGCTGCG",
        "variant": "8:37965285 C / CCTGGGCTGCG"
      }
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    "gnomAD_4": [
      {
        "@id": "http://gnomad.broadinstitute.org/variant/8-37965285-C-CCTGGGCTGCG?dataset=gnomad_r4",
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      }
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      "chromosome": "8",
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        {
          "allele": "GCTGGGCTGC",
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          "referenceAllele": "",
          "start": 37965304
        }
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        "CM000670.2:g.37965295_37965304dup"
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      "referenceSequence": "http://reg.genome.network/refseq/RS000056"
    },
    {
      "chromosome": "8",
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        {
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          "referenceAllele": "",
          "start": 37822822
        }
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      "referenceSequence": "http://reg.genome.network/refseq/RS000032"
    },
    {
      "chromosome": "8",
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        {
          "allele": "GCTGGGCTGC",
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          "referenceAllele": "",
          "start": 37941979
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      "hgvs": [
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      "referenceGenome": "NCBI36",
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    },
    {
      "coordinates": [
        {
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          "referenceAllele": "",
          "start": 6381
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      "referenceSequence": "http://reg.genome.network/refseq/RS002062"
    }
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          "referenceAllele": "",
          "start": 1314
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS748270",
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        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
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            "hgvs": "NP_000016.1:p.Arg395SerfsTer29"
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    {
      "coordinates": [
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          "start": 1312
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      "referenceSequence": "http://reg.genome.network/refseq/RS758684"
    },
    {
      "coordinates": [
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          "referenceAllele": "",
          "start": 668
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        "hgvs": "ENSP00000497740.1:p.Arg223SerfsTer?",
        "hgvsWellDefined": "ENSP00000497740.1:p.[Arg223_Cys225delinsSerAlaAla;Arg227Ala;Asp229_Lys235delinsProThrAlaArgArgGluAla;Val237_Val248delinsSerLysArgSerCysArgGluHisHisAlaAsnGlnGly;Lys249_Glu250insSer;Lys251_Leu252delinsGlyGluThrPro]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS769701"
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    {
      "coordinates": [
        {
          "allele": "GCGCAGCCCA",
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          "referenceAllele": "",
          "start": 1680
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      },
      "referenceSequence": "http://reg.genome.network/refseq/RS262124"
    },
    {
      "coordinates": [
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          "allele": "GCGCAGCCCA",
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          "referenceAllele": "",
          "start": 459
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      "hgvs": [
        "ENST00000520341.1:n.450_459dup"
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      "referenceSequence": "http://reg.genome.network/refseq/RS347406"
    },
    {
      "coordinates": [
        {
          "allele": "GCGCAGCCCA",
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          "referenceAllele": "",
          "start": 1381
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      "gene": "http://reg.genome.network/gene/GN000288",
      "geneNCBI_id": 155,
      "geneSymbol": "ADRB3",
      "hgvs": [
        "ENST00000614635.1:c.1175_1184dup"
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      "proteinEffect": {
        "hgvs": "ENSP00000480325.1:p.Arg395SerfsTer29",
        "hgvsWellDefined": "ENSP00000480325.1:p.[Arg395_Cys397delinsSerAlaAla;Arg399Ala;Asp401_Gly402delinsProThr;Ser404_Trp405delinsArgArg;Val407delinsPheLeuGly;Ser408_Ter409insPheLeuGlyLeuLysAspLysLysGlnGlnLeuCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS402283"
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    {
      "coordinates": [
        {
          "allele": "GCGCAGCCCA",
          "end": 1381,
          "referenceAllele": "",
          "start": 1381
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      "gene": "http://reg.genome.network/gene/GN000288",
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      "hgvs": [
        "NM_000025.2:c.1175_1184dup"
      ],
      "proteinEffect": {
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        "hgvsWellDefined": "NP_000016.1:p.[Arg395_Cys397delinsSerAlaAla;Arg399Ala;Asp401_Gly402delinsProThr;Ser404_Trp405delinsArgArg;Val407delinsPheLeuGly;Ser408_Ter409insPheLeuGlyLeuLysAspLysLysGlnGlnLeuCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS006090"
    },
    {
      "coordinates": [
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      "hgvs": [
        "NM_000025.3:c.1175_1184dup"
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      "proteinEffect": {
        "hgvs": "NP_000016.1:p.Arg395SerfsTer29",
        "hgvsWellDefined": "NP_000016.1:p.[Arg395_Cys397delinsSerAlaAla;Arg399Ala;Asp401_Gly402delinsProThr;Ser404_Trp405delinsArgArg;Val407delinsPheLeuGly;Ser408_Ter409insPheLeuGlyLeuLysAspLysLysGlnGlnLeuCys]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS662288",
      "MANE": {
        "maneVersion": "1.3",
        "maneStatus": "MANE Select",
        "nucleotide": {
          "Ensembl": {
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          "Ensembl": {
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          "RefSeq": {
            "hgvs": "NP_000016.1:p.Arg395SerfsTer29"
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        }
      }
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  ],
  "type": "nucleotide"
}