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      "proteinEffect": {
        "hgvs": "NP_001107854.1:p.Gly1344ValfsTer?",
        "hgvsWellDefined": "NP_001107854.1:p.[Gly1344_Arg1346delinsValTrp;Ser1348_Asp1350delinsAla;Ser1352_Gln1354delinsCysGly;Ser1356_Gln1357delinsLeuLeu;Pro1358_Leu1359insAla;Ser1360_Glu1367delinsAlaAlaProGluGlnValGlnLeu;Gln1369_Gln1372delinsSerArgAlaAla;Asp1373_Ile1374insSerAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS712126"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 3900,
          "referenceAllele": "",
          "start": 3900
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012363",
      "geneNCBI_id": 7249,
      "geneSymbol": "TSC2",
      "hgvs": [
        "NM_001318827.2:c.3790_3791insT"
      ],
      "proteinEffect": {
        "hgvs": "NP_001305756.1:p.Gly1264ValfsTer?",
        "hgvsWellDefined": "NP_001305756.1:p.[Gly1264_Arg1266delinsValTrp;Ser1268_Asp1270delinsAla;Ser1272_Gln1274delinsCysGly;Ser1276_Gln1277delinsLeuLeu;Pro1278_Leu1279insAla;Ser1280_Glu1287delinsAlaAlaProGluGlnValGlnLeu;Gln1289_Gln1292delinsSerArgAlaAla;Asp1293_Ile1294insSerAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS717605"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 3844,
          "referenceAllele": "",
          "start": 3844
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012363",
      "geneNCBI_id": 7249,
      "geneSymbol": "TSC2",
      "hgvs": [
        "NM_001318829.2:c.3754_3755insT"
      ],
      "proteinEffect": {
        "hgvs": "NP_001305758.1:p.Gly1252ValfsTer?",
        "hgvsWellDefined": "NP_001305758.1:p.[Gly1252_Arg1254delinsValTrp;Ser1256_Asp1258delinsAla;Ser1260_Gln1262delinsCysGly;Ser1264_Gln1265delinsLeuLeu;Pro1266_Leu1267insAla;Ser1268_Glu1275delinsAlaAlaProGluGlnValGlnLeu;Gln1277_Gln1280delinsSerArgAlaAla;Asp1281_Ile1282insSerAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS717607"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 3703,
          "referenceAllele": "",
          "start": 3703
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012363",
      "geneNCBI_id": 7249,
      "geneSymbol": "TSC2",
      "hgvs": [
        "NM_001318831.2:c.3367_3368insT"
      ],
      "proteinEffect": {
        "hgvs": "NP_001305760.1:p.Gly1123ValfsTer?",
        "hgvsWellDefined": "NP_001305760.1:p.[Gly1123_Arg1125delinsValTrp;Ser1127_Asp1129delinsAla;Ser1131_Gln1133delinsCysGly;Ser1135_Gln1136delinsLeuLeu;Pro1137_Leu1138insAla;Ser1139_Glu1146delinsAlaAlaProGluGlnValGlnLeu;Gln1148_Gln1151delinsSerArgAlaAla;Asp1152_Ile1153insSerAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS717609"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 3999,
          "referenceAllele": "",
          "start": 3999
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012363",
      "geneNCBI_id": 7249,
      "geneSymbol": "TSC2",
      "hgvs": [
        "NM_001318832.2:c.3931_3932insT"
      ],
      "proteinEffect": {
        "hgvs": "NP_001305761.1:p.Gly1311ValfsTer?",
        "hgvsWellDefined": "NP_001305761.1:p.[Gly1311_Arg1313delinsValTrp;Ser1315_Asp1317delinsAla;Ser1319_Gln1321delinsCysGly;Ser1323_Gln1324delinsLeuLeu;Pro1325_Leu1326insAla;Ser1327_Glu1334delinsAlaAlaProGluGlnValGlnLeu;Gln1336_Gln1339delinsSerArgAlaAla;Asp1340_Ile1341insSerAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS717610"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 4011,
          "referenceAllele": "",
          "start": 4011
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012363",
      "geneNCBI_id": 7249,
      "geneSymbol": "TSC2",
      "hgvs": [
        "NM_001363528.2:c.3901_3902insT"
      ],
      "proteinEffect": {
        "hgvs": "NP_001350457.1:p.Gly1301ValfsTer?",
        "hgvsWellDefined": "NP_001350457.1:p.[Gly1301_Arg1303delinsValTrp;Ser1305_Asp1307delinsAla;Ser1309_Gln1311delinsCysGly;Ser1313_Gln1314delinsLeuLeu;Pro1315_Leu1316insAla;Ser1317_Glu1324delinsAlaAlaProGluGlnValGlnLeu;Gln1326_Gln1329delinsSerArgAlaAla;Asp1330_Ile1331insSerAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS720739"
    },
    {
      "coordinates": [
        {
          "allele": "T",
          "end": 4080,
          "referenceAllele": "",
          "start": 4080
        }
      ],
      "gene": "http://reg.genome.network/gene/GN012363",
      "geneNCBI_id": 7249,
      "geneSymbol": "TSC2",
      "hgvs": [
        "NM_021055.3:c.3970_3971insT"
      ],
      "proteinEffect": {
        "hgvs": "NP_066399.2:p.Gly1324ValfsTer?",
        "hgvsWellDefined": "NP_066399.2:p.[Gly1324_Arg1326delinsValTrp;Ser1328_Asp1330delinsAla;Ser1332_Gln1334delinsCysGly;Ser1336_Gln1337delinsLeuLeu;Pro1338_Leu1339insAla;Ser1340_Glu1347delinsAlaAlaProGluGlnValGlnLeu;Gln1349_Gln1352delinsSerArgAlaAla;Asp1353_Ile1354insSerAlaGly]"
      },
      "referenceSequence": "http://reg.genome.network/refseq/RS728502"
    }
  ],
  "type": "nucleotide"
}